| GO term name | GO category | Gene symbols |
|---|
| 'de novo' pyrimidine nucleobase biosynthetic process | biological_process | MTOR |
| 3'-phosphoadenosine 5'-phosphosulfate metabolic process | biological_process | SULT1E1 |
| 3'-UTR-mediated mRNA stabilization | biological_process | ELAVL1 |
| 5-methylcytosine catabolic process | biological_process | TET2 |
| 5-methylcytosine metabolic process | biological_process | TET2 |
| 9-cis-retinoic acid biosynthetic process | biological_process | CYP1A1 |
| acetaldehyde metabolic process | biological_process | RELA |
| acetyl-CoA biosynthetic process | biological_process | ACLY |
| acetyl-CoA metabolic process | biological_process | ACLY |
| acid secretion | biological_process | DRD2 |
| acrosome reaction | biological_process | TRIM36 |
| actin cytoskeleton organization | biological_process | BCL6, SHC1, CFL1, CXCL1, PDGFA, KRAS, CDC42, RAC1, LIMK1, RND3, TMOD3, RHOA |
| actin cytoskeleton reorganization | biological_process | KIT, SHC1, ANXA1, PAK1, RHOA |
| actin filament branching | biological_process | CDC42 |
| actin filament bundle assembly | biological_process | ACTN4, CDC42, AIF1 |
| actin filament depolymerization | biological_process | CFL1 |
| actin filament organization | biological_process | BCL2, CTNNA1, CDC42, RAC1, CRHR2, TMOD3, CCL11 |
| actin filament polymerization | biological_process | ANG, RAC1, AIF1 |
| actin filament-based process | biological_process | SELE |
| actin polymerization or depolymerization | biological_process | GHRL |
| activated T cell proliferation | biological_process | FYN, CADM1 |
| activation of adenylate cyclase activity | biological_process | FSHR, CRHR1, EDNRA, LHCGR |
| activation of blood coagulation via clotting cascade | biological_process | F3 |
| activation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | XDH, HSPD1, F2R, PPARG, F3, CASP1, TNFSF10, CDKN1B, CASP3, FASLG, FAS, NGF, TNF, PDCD6, BCL2L11, SMAD3, BAX, NOD1, CDKN2A |
| activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | biological_process | CASP3, BAX |
| activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological_process | TNFSF10, FASLG, FAS, SMAD3, BAX |
| activation of GTPase activity | biological_process | WNT5A, CCL21, CXCL13, CCR7 |
| activation of innate immune response | biological_process | HMGB1, TLR4 |
| activation of JAK2 kinase activity | biological_process | PRLR |
| activation of JUN kinase activity | biological_process | CD40LG, WNT5A, MAP2K7, CCL19 |
| activation of MAPK activity | biological_process | FGF2, WNT5A, MAPK1, KIT, SHC1, FPR1, HGF, SAA1, TDGF1, EFNA1, INSR, IGF1, FGF1, MAP3K7, SOD1, TNF, TLR4, THBS1, IL1B, EGF, C5, CD74, NRG1, CXCR4, NOD2, GHRL, NOD1, PROK1, LPAR3 |
| activation of MAPK activity involved in innate immune response | biological_process | NOD2, ADAM8 |
| activation of MAPKK activity | biological_process | CRK, BMP4, F2R, BRAF, FLT1, EGFR, MAP3K7, NGF, EGF, KISS1R |
| activation of MAPKKK activity | biological_process | TNF |
| activation of meiosis involved in egg activation | biological_process | PLCB1 |
| activation of NF-kappaB-inducing kinase activity | biological_process | CHI3L1, MAP3K7, TLR3 |
| activation of phospholipase A2 activity | biological_process | ANG |
| activation of phospholipase A2 activity by calcium-mediated signaling | biological_process | EGFR |
| activation of phospholipase C activity | biological_process | EDNRA, SELE, EGFR, ANG |
| activation of phospholipase D activity | biological_process | CCL5 |
| activation of plasma proteins involved in acute inflammatory response | biological_process | F3 |
| activation of protein kinase A activity | biological_process | UCN |
| activation of protein kinase activity | biological_process | VEGFA, HMGB1, DRD2, PIK3CA, INSR, ITGB3, TGFB2 |
| activation of protein kinase B activity | biological_process | SRC, TXN, WNT5A, INSR, IGF1, FGF1, ANG, NRG1, PARK7, GAS6 |
| activation of protein kinase C activity | biological_process | LEP |
| activation of signaling protein activity involved in unfolded protein response | biological_process | BAX |
| activation of transmembrane receptor protein tyrosine kinase activity | biological_process | PRLR, GREM1, EGF, NRG1, ANGPT1 |
| activation-induced cell death of T cells | biological_process | AKT1, FAS, IL2RA |
| active induction of host immune response by virus | biological_process | TGFB1 |
| activin receptor signaling pathway | biological_process | INHBA, SMAD3, SMAD2 |
| acute inflammatory response | biological_process | VCAM1, TACR1, APOA2, PTGES, DEFB1, OGG1 |
| acute inflammatory response to antigenic stimulus | biological_process | OPRM1, ICAM1 |
| acute-phase response | biological_process | STAT3, MBL2, IL6R, SAA1, IL1RN, FN1, FGA, SERPINA1, AHSG, CRP, HP, APCS, IL6, HIF1A, IL22 |
| adaptive immune response | biological_process | HMGB1, CD79A, HLA-E, CTLA4, IFNG, ANXA1, FGA, PRKCB, CD4, FYN, TNFRSF21, CD74, C1QBP, MICA, IL2, MICB, CD1A, KLRK1, LILRB1 |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological_process | TGFB1 |
| adenohypophysis development | biological_process | DRD2, SOX2, GHRH |
| adenosine catabolic process | biological_process | ADA |
| adenosine metabolic process | biological_process | ADA |
| adenylate cyclase-activating adrenergic receptor signaling pathway | biological_process | DRD2 |
| adenylate cyclase-activating dopamine receptor signaling pathway | biological_process | OPRM1 |
| adenylate cyclase-activating G-protein coupled receptor signaling pathway | biological_process | FSHR, LHCGR, PTGER2, GHRH, UCN2 |
| adenylate cyclase-inhibiting dopamine receptor signaling pathway | biological_process | DRD2 |
| adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway | biological_process | HRH4 |
| adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | biological_process | OPRM1, SSTR5, PSAP |
| adenylate cyclase-inhibiting opioid receptor signaling pathway | biological_process | OPRM1 |
| adenylate cyclase-modulating G-protein coupled receptor signaling pathway | biological_process | PTGER4, DRD2, FPR1, CRHR2, RXFP1 |
| adherens junction assembly | biological_process | CTNNB1, SMAD7 |
| adherens junction organization | biological_process | SRC, CDH1, CTNNB1, CTNNA1, CDH3, ANG, CDC42, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
| adhesion of symbiont to host | biological_process | ICAM1, SCARB1 |
| adiponectin-activated signaling pathway | biological_process | ADIPOQ, ADIPOR2, ADIPOR1 |
| adipose tissue development | biological_process | LEP, ATF2, PIK3CA, ID2 |
| adrenal cortex formation | biological_process | WT1 |
| adrenal gland development | biological_process | WT1, MDK, INSR, CYP17A1, FSTL3, APOA1, CRH, NR5A1, WNT4 |
| adult behavior | biological_process | DRD2, PCDH17, PTEN |
| adult feeding behavior | biological_process | LEP, GHRL, NPY |
| adult heart development | biological_process | GJA1 |
| adult locomotory behavior | biological_process | NTF4, CXCL12, SNCG, PARK7, ID2, ADAM22 |
| adult walking behavior | biological_process | DRD2, UCHL1 |
| aerobic respiration | biological_process | CAT, UCN |
| aggressive behavior | biological_process | TACR1 |
| aging | biological_process | GSK3B, STAT3, DNMT1, PLA2G4A, CCL5, IGFBP2, CLU, APEX1, F3, IL10, AKT1, SHC1, SERPINF1, TNFRSF1B, CTNNA1, EDNRA, MMP7, FAS, CCL2, IL15, VCAM1, TIMP2, PTGS1, ADM, TIMP3, CCR2, IGF1, JUN, CRYAB, TGFB1, SOD1, TIMP1, SOCS3, FOS, IL1B, CP, ITGB2, ADA, AMH, CAT, CYP1A1, MPO, IL6, PTEN, RELA, DNMT3A, NTRK2, BAX, NFKB2, PAX2, CX3CL1, RETN, OGG1, DCN |
| aldosterone secretion | biological_process | AGTR2 |
| alkaloid metabolic process | biological_process | CYP1A2 |
| alpha-beta T cell differentiation | biological_process | BRAF, ANXA1 |
| ameboidal-type cell migration | biological_process | WNT5A |
| amelogenesis | biological_process | ITGA6, ATF2 |
| amine metabolic process | biological_process | VCAM1, CYP1A1 |
| AMPA glutamate receptor clustering | biological_process | APOE |
| amygdala development | biological_process | ESR2 |
| amyloid fibril formation | biological_process | CD36 |
| anaphase-promoting complex-dependent catabolic process | biological_process | CCNB1, PSMD9, AURKA, PSMD10, PLK1 |
| anatomical structure arrangement | biological_process | RAC1 |
| anatomical structure development | biological_process | WNT4 |
| anatomical structure formation involved in morphogenesis | biological_process | GATA3, BMP4, TP63, DLX5, NODAL, GATA5 |
| anatomical structure morphogenesis | biological_process | GATA3, F2R, HOXA11, FGF1, CYR61, RAC1, POU5F1, ERVW-1 |
| anatomical structure regression | biological_process | BMP4 |
| androgen biosynthetic process | biological_process | HSD3B2, SRD5A2, HSD17B3, CYP17A1, SCARB1, WNT4, SRD5A1 |
| androgen metabolic process | biological_process | AKR1D1, CYP19A1, SRD5A2, ADM, ESR1, SRD5A1 |
| androgen receptor signaling pathway | biological_process | CTNNB1, BRCA1, AR, RB1, ARID1A, TGFB1I1, FKBP4 |
| angiogenesis | biological_process | FGFR1, FGF2, VEGFA, BMP4, FGFR2, LEP, CXCL8, SHC1, NOTCH1, KDR, ID1, PLCD1, FLT4, CXCR3, ENG, COL4A2, FLT1, HMOX1, LEPR, CCL2, MMP14, TYMP, EFNA1, PIK3CA, NOS3, PTGS2, VEGFC, COL18A1, FN1, ATP5B, GREM1, JUN, FGF1, ITGAV, ANG, PDGFA, PDCD6, MEIS1, WNT7A, NRP1, ANGPT2, LAMA5, ANXA2, SERPINE1, FIGF, NRP2, EGF, PLAU, COL4A1, MMP2, PTEN, TGFB2, PTK2, HIF1A, TEK, HEY1, IL18, SIRT1, ADAM8, NAA15, JAG1, DLL4, PROK1, ANGPT1, CYP1B1, PLCD3 |
| angiogenesis involved in coronary vascular morphogenesis | biological_process | NRP1 |
| angiogenesis involved in wound healing | biological_process | ITGB3, GPX1, HPSE, CX3CL1 |
| angiotensin catabolic process in blood | biological_process | ACE |
| angiotensin maturation | biological_process | MME, ACE, CMA1, CTSG |
| angiotensin-activated signaling pathway | biological_process | AGTR1, AGTR2, CA2 |
| angiotensin-activated signaling pathway involved in heart process | biological_process | SRC |
| angiotensin-mediated drinking behavior | biological_process | TACR1 |
| angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure | biological_process | AGTR2 |
| animal organ development | biological_process | CTNNB1, ZEB1, PAX2 |
| animal organ formation | biological_process | GATA6 |
| animal organ morphogenesis | biological_process | GSK3B, BCL2, GATA3, FGF2, CDX1, MAPK1, FGFR2, VDR, BRAF, ITGA2, GATA2, CCL2, VEGFC, COL18A1, INSR, GREM1, TNF, PDGFA, NRP1, LAMA5, RELA, TP63, JAG1, GATA5, DCN |
| animal organ regeneration | biological_process | CCND1, PPARG, IGF2R, SHC1, NOTCH1, CDKN1A, HGF, GSTP1, CCL2, LIF, LIFR, FLT3, ADM, MKI67, CXCL12, TGFB1, APOA1, APOA2, SOCS3, ANGPT2, WNT1, GAS6, TEK, NR0B2 |
| anion transmembrane transport | biological_process | ABCC4, SLC26A8 |
| anion transport | biological_process | SLC26A8 |
| anterior neural tube closure | biological_process | FOLR1 |
| anterior/posterior axis specification | biological_process | BMP4, CDX1, CTNNB1, AURKA, NODAL |
| anterior/posterior axis specification, embryo | biological_process | WNT5A, TDGF1 |
| anterior/posterior pattern specification | biological_process | NR2F2, CDX1, WNT5A, HOXB2, HOXA10, HNF1B, HOXA11, SMAD2, SMAD4, PCSK5, EMX2, NODAL |
| anterograde axonal transport | biological_process | SOD1 |
| anti-Mullerian hormone signaling pathway | biological_process | AMHR2 |
| antibacterial humoral response | biological_process | HLA-E, ADM, ANG, LTF, SLPI, DEFB1, NPY |
| antibacterial peptide production | biological_process | KLK3 |
| antifungal humoral response | biological_process | ADM, ANG, LTF, NPY |
| antigen processing and presentation | biological_process | HLA-DRB1, HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, IFNG, HLA-B, HLA-DQA1, CD74, HLA-DPB1, MICA, MICB, ULBP2, HLA-DRA |
| antigen processing and presentation of endogenous antigen | biological_process | CD74 |
| antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent | biological_process | ABCB1 |
| antigen processing and presentation of endogenous peptide antigen via MHC class Ib | biological_process | HLA-E |
| antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent | biological_process | ABCB1 |
| antigen processing and presentation of exogenous peptide antigen via MHC class I | biological_process | FCER1G |
| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological_process | CD36, ITGB5, HLA-C, HLA-E, HLA-G, HLA-A, PSMD9, ITGAV, PSMD10, HLA-B |
| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | biological_process | HLA-C, HLA-E, HLA-G, HLA-A, HLA-B |
| antigen processing and presentation of exogenous peptide antigen via MHC class II | biological_process | HLA-DRB1, FCER1G, HLA-DQA1, CD74, HLA-DPB1, CTSD, KIFAP3, HLA-DRA |
| antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent | biological_process | ABCB1 |
| antigen processing and presentation of peptide antigen via MHC class I | biological_process | ACE, HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, HLA-B |
| antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological_process | HLA-DRB1, HLA-DQA1, HLA-DPB1, HLA-DRA |
| antigen processing and presentation, exogenous lipid antigen via MHC class Ib | biological_process | CD1A |
| antral ovarian follicle growth | biological_process | ESR1 |
| aorta development | biological_process | PRDM1, LOXL1 |
| aorta morphogenesis | biological_process | JAG1 |
| aortic valve morphogenesis | biological_process | GATA3, NOTCH1, EFNA1, TWIST1 |
| apical junction assembly | biological_process | CTNNA1, RHOC, RHOA |
| apolipoprotein A-I-mediated signaling pathway | biological_process | ITGB3, ITGAV, RHOA |
| apoptotic cell clearance | biological_process | HMGB1, CD36, ALOX15, AXL, ITGAV, GAS6, TYRO3 |
| apoptotic chromosome condensation | biological_process | GPER1 |
| apoptotic DNA fragmentation | biological_process | HMGB1, CASP3, DICER1, FOXL2 |
| apoptotic mitochondrial changes | biological_process | GCLC, BCL2, NDUFS1, AKT1, BCL2L1, BAX, MCL1, CDKN2A |
| apoptotic process | biological_process | BCL2, TNFRSF1A, MAPK1, FGFR2, CLU, GJA1, IGFBP3, CHI3L1, AKT1, BRCA1, NFKB1, CASP1, TNFSF10, AHR, CASP3, FASLG, CXCR3, TNFRSF1B, LGALS1, TIA1, PAEP, HMOX1, G0S2, FAS, CHEK2, GREM1, IFNG, MAP3K7, PRKCB, IL1A, TP53, BIRC5, TLR2, PDCD6, SGK1, TNFRSF11B, RB1, KLF11, MAP2K7, NR3C1, BCL2L11, TNFRSF21, PSMD10, IL1B, PAK4, GPX1, ITGB2, LTA, IL2RA, C1QBP, PTEN, BCL2L1, FOXO1, BAX, CXCR4, PAK1, MCL1, SIRT1, ATM, NOD1, GPER1, DAPK1, PIM2, CADM1, IL24, CDKN2A, CSE1L, TP63, DAD1, SEMA3A, IL17A, FHIT, SRA1 |
| apoptotic process in bone marrow | biological_process | BCL2L1 |
| apoptotic process involved in blood vessel morphogenesis | biological_process | BAX |
| apoptotic process involved in embryonic digit morphogenesis | biological_process | NOTCH1, BCL2L11, BAX |
| apoptotic process involved in heart morphogenesis | biological_process | CYR61 |
| apoptotic process involved in morphogenesis | biological_process | CRYAB |
| apoptotic signaling pathway | biological_process | CASP3, FASLG, TNFRSF1B, CD40, FAS, TNF, TLR4, PDCD6, TNFRSF11B, TLR3, TNFRSF21, BAX, DAPK1 |
| arachidonic acid metabolic process | biological_process | PLA2G4A, ALOX15, CYP1B1 |
| arachidonic acid secretion | biological_process | PLA2G4A, ACE, DRD2, ANXA1, KISS1R |
| arginine catabolic process | biological_process | NOS2, NOS3 |
| arginine metabolic process | biological_process | ARG2 |
| aromatic amino acid family metabolic process | biological_process | GSTZ1 |
| aromatic compound catabolic process | biological_process | PON1, EPHX1 |
| arterial endothelial cell differentiation | biological_process | NOTCH1, HEY1 |
| artery morphogenesis | biological_process | VEGFA, ENG, APOE, SMAD7, NRP1, PRDM1 |
| artery smooth muscle contraction | biological_process | EDNRA, EDN1 |
| associative learning | biological_process | DRD2, TACR1, NPTX2, CRH, UCN |
| astrocyte activation | biological_process | CNTF |
| astrocyte cell migration | biological_process | CCL3, CCL2, MMP14 |
| astrocyte development | biological_process | VIM, TLR4 |
| astrocyte differentiation | biological_process | STAT3, NOTCH1, LIF, HES5 |
| asymmetric protein localization | biological_process | WNT7A |
| ATP biosynthetic process | biological_process | ATP5A1, ATP5B, TGFB1 |
| ATP hydrolysis coupled proton transport | biological_process | ATP5A1, ATP5B |
| ATP metabolic process | biological_process | NDUFS1, ATP5A1, ATP5B |
| ATP synthesis coupled electron transport | biological_process | NDUFS1 |
| ATP synthesis coupled proton transport | biological_process | ATP5A1, ATP5B |
| ATP transport | biological_process | GJA1 |
| ATP-dependent chromatin remodeling | biological_process | ARID1A, HDAC2, ACTB, HDAC1, MBD2 |
| atrial cardiac muscle cell action potential | biological_process | GJA1 |
| atrial cardiac muscle tissue morphogenesis | biological_process | WNT2 |
| atrial septum morphogenesis | biological_process | CYR61 |
| atrial ventricular junction remodeling | biological_process | GJA1 |
| atrioventricular canal development | biological_process | SMAD4 |
| atrioventricular node development | biological_process | NOTCH1 |
| atrioventricular valve formation | biological_process | HEY1, SMAD4, OLFM1 |
| atrioventricular valve morphogenesis | biological_process | NOTCH1, CYR61 |
| attachment of GPI anchor to protein | biological_process | PLAUR |
| auditory behavior | biological_process | DRD2 |
| auditory receptor cell development | biological_process | FGFR1 |
| auditory receptor cell differentiation | biological_process | HES5, JAG1 |
| auditory receptor cell fate commitment | biological_process | NOTCH1 |
| auditory receptor cell fate determination | biological_process | HES5 |
| auditory receptor cell morphogenesis | biological_process | RAC1 |
| auditory receptor cell stereocilium organization | biological_process | SOD1 |
| autophagic cell death | biological_process | CDKN1B |
| autophagosome assembly | biological_process | GABARAPL1 |
| autophagy | biological_process | HMGB1, CTSB, CTSD, PARK7, FOXO1, GABARAPL1, PTPN22 |
| axial mesodermal cell fate specification | biological_process | NODAL |
| axis elongation | biological_process | WNT5A |
| axon ensheathment | biological_process | NRG1 |
| axon extension | biological_process | ITGB1 |
| axon extension involved in axon guidance | biological_process | NRP1, NRP2, SEMA3A |
| axon guidance | biological_process | GATA3, WNT5A, MAPK1, NCAM1, EFNA1, BDNF, L1CAM, CXCL12, FYN, NRP1, NRP2, NRAS, KRAS, CSF1R, RAC1, TGFB2, PTK2, DPYSL2, NECTIN1, SMAD4, DLX5, SEMA3A, SEMA3C, NTN4 |
| axon regeneration | biological_process | BCL2, FOLR1, CTNNA1, JUN |
| axon target recognition | biological_process | UCHL1 |
| axonal fasciculation | biological_process | NRP1, SEMA3A |
| axonal transport of mitochondrion | biological_process | UCHL1, HIF1A |
| axonogenesis | biological_process | GSK3B, BCL2, WNT5A, FGFR2, NOTCH1, DRD2, UCHL1, STMN1, PRELP, S100A6, WNT7A, PAK1, TLR9, PAX2, DLX5 |
| axonogenesis involved in innervation | biological_process | NRP1, SEMA3A |
| B cell activation | biological_process | HSPD1, CD40, CD79A, PRKCB, IL4 |
| B cell apoptotic process | biological_process | BCL2L11, TNFRSF21, BAX |
| B cell chemotaxis | biological_process | CXCL13, GAS6 |
| B cell chemotaxis across high endothelial venule | biological_process | CXCL13 |
| B cell costimulation | biological_process | IL4 |
| B cell cytokine production | biological_process | HSPD1 |
| B cell differentiation | biological_process | MSH2, BCL2, BCL6, CD40LG, PIK3R1, IL10, CD79A, VCAM1, IL11, FLT3, ITGB1, IL4, ADAM17 |
| B cell homeostasis | biological_process | BCL2, CASP3, BCL2L11, BAX, FOXP3 |
| B cell homeostatic proliferation | biological_process | BAX |
| B cell lineage commitment | biological_process | BCL2 |
| B cell mediated immunity | biological_process | MSH2, FAS |
| B cell negative selection | biological_process | BAX |
| B cell proliferation | biological_process | BCL2, HSPD1, CD40LG, IL10, CD40, CD79A |
| B cell proliferation involved in immune response | biological_process | TLR4 |
| B cell receptor apoptotic signaling pathway | biological_process | BAX |
| B cell receptor signaling pathway | biological_process | BCL2, MAPK1, CD79A, CTLA4, PRKCB |
| B-1 B cell homeostasis | biological_process | HIF1A |
| baculum development | biological_process | ESR1 |
| base-excision repair | biological_process | HMGA2, HMGB1, APEX1, HMGA1, XRCC1, TP53, OGG1 |
| base-excision repair, base-free sugar-phosphate removal | biological_process | APEX1 |
| base-excision repair, DNA ligation | biological_process | XRCC1 |
| basement membrane organization | biological_process | MMP11, COL4A1 |
| basophil chemotaxis | biological_process | VEGFA |
| behavior | biological_process | CCL3, NPY |
| behavioral fear response | biological_process | BCL2, MDK, ESR2 |
| behavioral response to cocaine | biological_process | DRD2 |
| behavioral response to ethanol | biological_process | OPRM1, DRD2, CRHBP, HDAC2 |
| behavioral response to formalin induced pain | biological_process | P2RX3 |
| behavioral response to nicotine | biological_process | PPARA |
| behavioral response to pain | biological_process | TACR1, THBS1, P2RX3 |
| behavioral response to starvation | biological_process | SIRT1 |
| benzene metabolic process | biological_process | CYP2E1 |
| Bergmann glial cell differentiation | biological_process | MAPK1, VIM |
| beta-amyloid metabolic process | biological_process | MME, ACE |
| beta-catenin destruction complex assembly | biological_process | GSK3B |
| beta-catenin destruction complex disassembly | biological_process | GSK3B, CTNNB1, WNT1 |
| beta-catenin-TCF complex assembly | biological_process | CTNNB1, TERT, MYC, HDAC1 |
| bicarbonate transport | biological_process | CFTR, CA2, SLC26A8 |
| bicellular tight junction assembly | biological_process | ITGB1, ACTN4, CLDN3 |
| bile acid and bile salt transport | biological_process | AKR1C1 |
| bile acid biosynthetic process | biological_process | AKR1D1, STAR |
| bile acid catabolic process | biological_process | AKR1D1 |
| bile acid metabolic process | biological_process | LEP, NR5A2, AKR1C1 |
| bile acid signaling pathway | biological_process | VDR |
| binding of sperm to zona pellucida | biological_process | OVGP1 |
| biological_process | biological_process | BGN, ABCC4, A1BG, NRM, NUDT6, IL22RA1, TIMP4, HRH4, RETN, MST1 |
| biomineral tissue development | biological_process | SPP1 |
| biphenyl metabolic process | biological_process | SRD5A2, STAR, CYP17A1 |
| blastocyst development | biological_process | POU5F1, DAD1 |
| bleb assembly | biological_process | LPAR3 |
| blood circulation | biological_process | MTHFR, HOXB2, ADM, CXCL12, CXCL10, DLL4, NPY |
| blood coagulation | biological_process | GATA3, F2R, CD36, F3, ANXA5, ITGA2, GATA2, FCER1G, ITGB3, FGA, SERPINA1, PLAT, C3, FYN, PLAU, CDC42, RAC1, HDAC2, GAS6, PLAUR, F2RL1, HDAC1, HIST2H3A, GATA6, P2RX3, CPB2, GATA5 |
| blood coagulation, common pathway | biological_process | FGA |
| blood coagulation, extrinsic pathway | biological_process | F3 |
| blood coagulation, fibrin clot formation | biological_process | FBLN1, FGA |
| blood coagulation, intrinsic pathway | biological_process | A2M, C1QBP |
| blood vessel development | biological_process | BMP4, AHR, ITGAV, TGFB2, PTK2, HIF1A, FOXO1, ATP7A |
| blood vessel endothelial cell migration | biological_process | ID1, APOA1, GPX1, SCARB1 |
| blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological_process | BMP4 |
| blood vessel lumenization | biological_process | DLL4 |
| blood vessel maturation | biological_process | MMP2 |
| blood vessel morphogenesis | biological_process | FGFR1, NR2F2, GJA1, ID1, FLT4, FLT1, MEIS1, ANGPT2, COL4A1, EDN1, HIF1A, CYP1B1 |
| blood vessel remodeling | biological_process | BGN, ACE, AXL, AGTR2, LIF, NOS3, CCR2, TGFB2, BAX, ATP7A, JAG1, DLL4, SEMA3C |
| BMP signaling pathway | biological_process | EGR1, BMP4, ID1, ENG, BMP6, BMPR1B, SMAD7, GDF9, SMAD4, DLX5, NODAL |
| BMP signaling pathway involved in heart induction | biological_process | BMP4, POU5F1 |
| BMP signaling pathway involved in nephric duct formation | biological_process | BMP4 |
| BMP signaling pathway involved in renal system segmentation | biological_process | BMP4 |
| BMP signaling pathway involved in ureter morphogenesis | biological_process | BMP4 |
| body fluid secretion | biological_process | ANXA2, EDN1 |
| bone development | biological_process | BMP4, FGFR2, PTGER4, SPARC, HSD17B1, MMP14, SRD5A2, WNT1, TWIST1, SRD5A1, STC1 |
| bone growth | biological_process | LEP, LEPR |
| bone mineralization | biological_process | MMP13, FGFR2, ALOX15, PTN, PTGS2, KLF10 |
| bone mineralization involved in bone maturation | biological_process | LEP, IGF1 |
| bone morphogenesis | biological_process | CDX1, MMP13, FGFR2, LTF, DLX5 |
| bone regeneration | biological_process | POSTN |
| bone remodeling | biological_process | RASSF2, IL6 |
| bone resorption | biological_process | SRC, CTNNB1, RAC1 |
| bone trabecula formation | biological_process | MMP2 |
| brain development | biological_process | FGFR1, BMP4, DNMT1, BRCA1, SLC6A4, NOTCH1, ID1, AGTR2, BRCA2, FAS, STMN1, PTN, MTOR, STAR, CXCL12, BCL2L11, COL4A1, NRG1, HES5, DPYSL2, BAX, PLCB1, ATM, AGER, EMX2, IRS2, PAFAH1B2, NODAL |
| brain morphogenesis | biological_process | SLC6A4, PTEN, PAX2 |
| brain renin-angiotensin system | biological_process | AGTR2 |
| brain-derived neurotrophic factor receptor signaling pathway | biological_process | BDNF, NTRK2 |
| brainstem development | biological_process | SMAD4 |
| branch elongation involved in mammary gland duct branching | biological_process | TGFB1 |
| branch elongation involved in salivary gland morphogenesis | biological_process | FGFR2 |
| branch elongation involved in ureteric bud branching | biological_process | FGF1 |
| branching involved in blood vessel morphogenesis | biological_process | VEGFA, CTNNB1, ENG, EDNRA, NRP1, COL4A1, EDN1, DLL4, NOTCH4 |
| branching involved in labyrinthine layer morphogenesis | biological_process | FGFR2, IL10, ADM, SOCS3 |
| branching involved in mammary gland duct morphogenesis | biological_process | SRC, CSF1, CCL11 |
| branching involved in prostate gland morphogenesis | biological_process | BMP4, FGFR2 |
| branching involved in salivary gland morphogenesis | biological_process | FGFR1, FGFR2, LAMA5, IL6 |
| branching involved in ureteric bud morphogenesis | biological_process | BCL2, FGF2, BMP4, CTNNB1, WT1, HOXA11, GREM1, MYC, LAMA5, WNT1, SMAD4, PAX2, WNT4 |
| branching morphogenesis of a nerve | biological_process | FGFR2, DRD2 |
| branching morphogenesis of an epithelial tube | biological_process | VEGFA, MET, BMP4, NOTCH1, MMP14, HNF1B, LAMA5, SPRY2, EGF, PAK1, WNT4 |
| branchiomotor neuron axon guidance | biological_process | NRP1, SEMA3A |
| bronchus development | biological_process | BMP4 |
| brown fat cell differentiation | biological_process | ITGA6, PTGS2, ADIPOQ, RARRES2 |
| bud dilation involved in lung branching | biological_process | BMP4 |
| bud elongation involved in lung branching | biological_process | YAP1, BMP4, FGFR2, SPRY2 |
| bud outgrowth involved in lung branching | biological_process | TNC |
| bundle of His development | biological_process | ID2 |
| C-5 methylation of cytosine | biological_process | DNMT1, DNMT3A, DNMT3B |
| C-terminal protein deglutamylation | biological_process | FOLH1 |
| C21-steroid hormone biosynthetic process | biological_process | AKR1B1, STAR, CYP11A1 |
| C21-steroid hormone metabolic process | biological_process | AKR1D1, CYP11A1 |
| calcium ion homeostasis | biological_process | ADM, AGER |
| calcium ion transmembrane transport | biological_process | OPRM1, ANXA5, ITGAV, GAS6, TRPV1 |
| calcium ion transport | biological_process | CCL5, CCL3, CCR1, CCR5, VDR, PRKCB, FYN, TRPV1, NPY |
| calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | biological_process | CLDN5, CLDN4, CLDN3, CLDN7 |
| calcium-independent cell-matrix adhesion | biological_process | FN1, ITGB1 |
| calcium-mediated signaling | biological_process | CXCL8, CCL3, CCR5, CXCR3, AGTR1, SELE, EDN1, CXCR4, KISS1R |
| calcium-mediated signaling using intracellular calcium source | biological_process | KDR, VCAM1, SELP, PTGFR, NTRK2 |
| camera-type eye development | biological_process | BMP4, WT1, CRYAB, BMPR1B, CYP1A1, HES5, JAG1, PAX2 |
| camera-type eye morphogenesis | biological_process | VEGFA, BMP4, HIF1A, NECTIN1, AQP5 |
| camera-type eye photoreceptor cell differentiation | biological_process | PROM1 |
| cAMP biosynthetic process | biological_process | ADM, UCN2 |
| cAMP-mediated signaling | biological_process | ADM, GHRH, KSR1 |
| canonical glycolysis | biological_process | ENO2, ENO1 |
| canonical Wnt signaling pathway | biological_process | GSK3B, CCND1, WNT5A, CTNNB1, WNT2, SDC1, CDH3, MYC, WNT7A, EGF, WNT1, CDC42, PTEN, WNT4 |
| canonical Wnt signaling pathway involved in metanephric kidney development | biological_process | GATA3 |
| canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological_process | WNT1 |
| canonical Wnt signaling pathway involved in negative regulation of apoptotic process | biological_process | CTNNB1, WNT1 |
| canonical Wnt signaling pathway involved in positive regulation of apoptotic process | biological_process | GSK3B |
| canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation | biological_process | CTNNB1 |
| canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | biological_process | CTNNB1 |
| carbohydrate catabolic process | biological_process | AMY2A |
| carbohydrate metabolic process | biological_process | GSK3B, AKR1B1, PGM1, CHI3L1, AKT1, INSR, IGF2, AMY2A, GALT, HPSE, GBGT1, CHST6, CHST2, OVGP1 |
| carbohydrate transport | biological_process | AKT1 |
| carbon catabolite regulation of transcription | biological_process | USF1 |
| carbon dioxide transport | biological_process | CA2, AQP5 |
| carbon tetrachloride metabolic process | biological_process | CYP2E1 |
| carboxylic acid catabolic process | biological_process | PON1 |
| carboxylic acid metabolic process | biological_process | MIF |
| cardiac atrium morphogenesis | biological_process | NOTCH1, DLL4 |
| cardiac cell development | biological_process | MTOR |
| cardiac cell fate determination | biological_process | POU5F1 |
| cardiac chamber development | biological_process | ARID1A |
| cardiac chamber formation | biological_process | NOTCH1 |
| cardiac conduction | biological_process | GJA1 |
| cardiac conduction system development | biological_process | CDC42, NRG1 |
| cardiac epithelial to mesenchymal transition | biological_process | WNT2, NOTCH1, TGFB2, HEY1, OLFM1 |
| cardiac left ventricle morphogenesis | biological_process | NOTCH1 |
| cardiac muscle cell apoptotic process | biological_process | HSP90AA1 |
| cardiac muscle cell development | biological_process | MTOR |
| cardiac muscle cell differentiation | biological_process | ITGB1, ARID1A, NRG1, GATA6 |
| cardiac muscle cell fate commitment | biological_process | WT1 |
| cardiac muscle cell myoblast differentiation | biological_process | NRG1 |
| cardiac muscle cell proliferation | biological_process | NOTCH1, TGFB2 |
| cardiac muscle contraction | biological_process | PIK3CA, MTOR, CXCR4 |
| cardiac muscle fiber development | biological_process | VEGFA |
| cardiac muscle hypertrophy | biological_process | LEP, HDAC2 |
| cardiac muscle hypertrophy in response to stress | biological_process | GATA6 |
| cardiac muscle tissue development | biological_process | MTOR, ITGB1, PTEN, GATA6 |
| cardiac muscle tissue morphogenesis | biological_process | NOTCH1 |
| cardiac myofibril assembly | biological_process | PDGFRA |
| cardiac neural crest cell development involved in heart development | biological_process | MAPK1 |
| cardiac neural crest cell development involved in outflow tract morphogenesis | biological_process | TWIST1, JAG1 |
| cardiac neural crest cell migration involved in outflow tract morphogenesis | biological_process | FOLR1, TWIST1 |
| cardiac right atrium morphogenesis | biological_process | NOTCH1 |
| cardiac right ventricle formation | biological_process | NOTCH1 |
| cardiac right ventricle morphogenesis | biological_process | GATA3, JAG1, SEMA3C |
| cardiac septum development | biological_process | BMP4, PRDM1, SMAD4, PCSK5 |
| cardiac septum morphogenesis | biological_process | NOTCH1, HEY1, JAG1 |
| cardiac vascular smooth muscle cell development | biological_process | VEGFA, NOTCH1 |
| cardiac vascular smooth muscle cell differentiation | biological_process | GATA6 |
| cardiac ventricle morphogenesis | biological_process | NOTCH1, HIF1A, HEY1, DLL4 |
| cardioblast differentiation | biological_process | TGFB2 |
| cardiolipin acyl-chain remodeling | biological_process | PLA2G4A |
| cardiovascular system development | biological_process | APOE |
| cartilage condensation | biological_process | BMPR1B, WNT7A, TGFB2 |
| cartilage development | biological_process | BMP4, WNT5A, MMP13, CHI3L1, CD44, BMP6, ZEB1, TIMP1, BMPR1B, WNT7A, EDN1, HIF1A, HES5, GHRL, ATP7A, IHH, IL17F |
| cartilage development involved in endochondral bone morphogenesis | biological_process | HOXA11 |
| cartilage morphogenesis | biological_process | SNAI1 |
| catagen | biological_process | TGFB2 |
| catechol-containing compound metabolic process | biological_process | COMT |
| catecholamine biosynthetic process | biological_process | CRHR2 |
| catecholamine metabolic process | biological_process | MAOA, COMT, ATP7A |
| catenin import into nucleus | biological_process | CTNNB1 |
| cation transmembrane transport | biological_process | P2RX3 |
| cation transport | biological_process | ATP7A, P2RX3 |
| caveolin-mediated endocytosis | biological_process | MAPK1 |
| CD4-positive, alpha-beta T cell activation | biological_process | STOML2 |
| CD4-positive, alpha-beta T cell differentiation | biological_process | BRAF |
| CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | biological_process | FOXP3 |
| CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment | biological_process | FOXP3 |
| CD8-positive, alpha-beta T cell activation | biological_process | HLA-E |
| CD8-positive, alpha-beta T cell differentiation involved in immune response | biological_process | IFNG |
| CD8-positive, alpha-beta T cell lineage commitment | biological_process | BCL2 |
| cell activation | biological_process | GATA3, CCL3, PDGFRA, FN1, IGF1, TGFB1, TIMP1, PDGFA |
| cell adhesion | biological_process | SRC, CDH1, ITGA6, ITGA3, CD36, CTNNB1, SPP1, CCR1, CXCR3, CTNNA1, ENG, ITGA2, ITGB5, LAMA1, CD44, KITLG, AZGP1, PECAM1, CCL2, NCAM1, VCAN, VCAM1, SELP, SELE, ITGB6, CDH3, TNC, L1CAM, COL18A1, CXCL12, FN1, ITGB3, ITGB1, ITGAV, CD4, CYR61, PCDH17, TGFB1I1, LAMA5, THBS1, NRP2, ITGB2, ADA, ICAM1, RAC1, HPSE, HES5, GAS6, TYRO3, NECTIN1, ADAM17, NECTIN3, CADM1, ADAM22, IGFBP7, RND3, CX3CL1, IL2, TRO, MUC16, LAMC2, POSTN, NECTIN4, CYP1B1, OLFM4, CADM2, MUC4, MMP24, LAMC1, CCL11, CCR8 |
| cell adhesion mediated by integrin | biological_process | ITGA6, ITGA2, ICAM1, ADAM17 |
| cell aging | biological_process | BCL2, MIF, BRCA2, MTOR, PRELP, SOD1, TP53, ICAM1, SIRT1, TP63 |
| cell chemotaxis | biological_process | KIT, PDGFRA, AGTR1, ENG, HGF, CXCL1, VCAM1, CXCL2, CXCL5, CXCL12, CCL25, CCL21, CCL22, CXCL14, C5, CX3CL1, CXCL6, CCL27 |
| cell communication | biological_process | GJA1, ANG, CCL16, NRG1, CCL19, JAG1, DLL4 |
| cell communication by chemical coupling | biological_process | GJA1 |
| cell communication by electrical coupling | biological_process | GJA1 |
| cell communication by electrical coupling involved in cardiac conduction | biological_process | GJA1 |
| cell cycle | biological_process | H2AFX, MLH1, SRC, CCND1, HMGA2, MAPK1, CCNB1, BRCA1, AHR, CDKN1B, RASSF2, CDKN1A, CDKN2A, BRCA2, MKI67, CHEK2, AURKA, TP53, SUV39H1, BIRC5, LATS1, RB1, NR3C1, PAK4, PLK1, KAT2B, ATM, GPER1, PIM2, SUV39H2, Sep-09, FSD1, RHOA, TET2, SMPD3 |
| cell cycle arrest | biological_process | MSH2, INHBA, IL12B, CXCL8, CDKN1B, CDKN1A, CDKN2A, IL12A, MTOR, SOX2, IFNG, TGFB1, INHA, TP53, MYC, RB1, THBS1, TGFB2, SMAD3, GAS6, KAT2B, ATM, CAB39L, RPRM |
| cell cycle checkpoint | biological_process | RB1 |
| cell death | biological_process | CLU, CDKN1B, HMOX1, PTGER3, TGFB2, IL17A |
| cell development | biological_process | INHBA, INHA, MSTN, GDF9, ID2, GATA6, GDF15, GATA5, MAF |
| cell differentiation | biological_process | GSK3B, INHBA, FGF2, VEGFA, BMP4, CDX1, WNT5A, LGALS3, AKT1, CTNNB1, NOTCH1, NME1, KDR, SPP1, CSF1, BRAF, AXL, JAK1, GATA2, TYK2, FLT1, CNTF, TDGF1, STMN1, TYMP, MDK, BMP6, ARNT, FLT3, SRD5A2, L1CAM, VEGFC, ZEB1, FGF1, ANG, INHA, TP53, SUV39H1, FYN, BMPR1B, SOX15, NRP1, TGFB1I1, ANGPT2, LAMA5, FIGF, NRP2, AMH, PRM1, CDC42, FOXL2, NTRK2, HIF1A, HES5, FOXO1, DPYSL2, NR5A1, MCL1, RARRES2, SIRT1, TWIST1, GPER1, CADM1, TP63, NAA15, SLC26A8, SUV39H2, PAX2, WNT4, DLL4, ANGPT1, SEMA3A, SFRP4, NOTCH4, CHD5, SEMA3C, NANOG, SRD5A1, KLRK1, SRA1 |
| cell differentiation in hindbrain | biological_process | GATA2 |
| cell differentiation in spinal cord | biological_process | NOTCH1 |
| cell differentiation involved in embryonic placenta development | biological_process | KRT19 |
| cell division | biological_process | CCND1, HMGA2, CCNB1, CHEK2, AURKA, BIRC5, LATS1, RB1, NR3C1, PLK1, Sep-09, FSD1, RHOA |
| cell fate commitment | biological_process | GATA3, BMP4, WNT5A, PPARG, FGFR2, WNT2, NOTCH1, CASP3, WNT7A, TGFB1I1, SPRY2, PRDM1, WNT1, SMAD2, GATA6, WNT4, NODAL, GATA5 |
| cell fate commitment involved in formation of primary germ layer | biological_process | POU5F1 |
| cell fate determination | biological_process | GATA3, CTNNB1, GATA2, MCL1, JAG1, PAX2, NOTCH4 |
| cell fate specification | biological_process | CTNNB1, NOTCH1, ITGB1 |
| cell growth | biological_process | BCL2, AR, MTOR, ITGB3, ITGAV, TGFB1, PAK4, IL6, EDN1, TGFB2, ATAD3A |
| cell growth involved in cardiac muscle cell development | biological_process | AGTR2 |
| cell junction assembly | biological_process | ACTB |
| cell maturation | biological_process | FGFR1, GATA3, VEGFA, PPARG, CTNNB1, AXL, GATA2, IL15, CCL21, HES5, CCL19, ID2 |
| cell migration | biological_process | GSK3B, FGFR1, SRC, WNT5A, IL12B, SDC4, ENG, JAK1, TYK2, FLT1, MMP14, SDC1, EFNA1, MDK, IL12A, ITGB3, ITGB1, ITGAV, ANG, TGFB1, FYN, SNAI1, NRP1, LAMA5, THBS1, PAK4, RAC1, PTEN, TGFB2, NRG1, GAS6, CXCR4, NODAL, LAMC1, RHOA |
| cell migration involved in endocardial cushion formation | biological_process | NOTCH1, ENG |
| cell migration involved in gastrulation | biological_process | NODAL |
| cell migration involved in sprouting angiogenesis | biological_process | FGF2, VEGFA, KDR, TDGF1, GREM1, ITGB1, NRP1 |
| cell morphogenesis | biological_process | BCL2, GATA3, YAP1, BCL6, CLU, VDR, HGF, GREM1, EGFR, TGFB2, NRG1, ADAM8 |
| cell morphogenesis involved in differentiation | biological_process | CTNNB1, DKK1 |
| cell morphogenesis involved in neuron differentiation | biological_process | RB1, ID2 |
| cell motility | biological_process | ENG, RAC1, PTK2, ADAM17 |
| cell projection assembly | biological_process | PDGFA |
| cell projection organization | biological_process | AKT1, MTOR, AURKA |
| cell proliferation | biological_process | BCL2, SRC, TXN, YAP1, MET, STAT3, PCNA, MIF, AKT1, CTNNB1, SERPINF1, AR, CSF1, UCHL1, BRCA2, EDNRA, ITGA2, HGF, CXCL1, KITLG, IGFBP4, ZEB1, MKI67, IGF1, EGFR, FGF1, TGFB1, IL1A, TP53, ERBB2, CYR61, LAMA5, FIGF, PAK4, GPX1, PRL, IL2RA, CD74, CYP1A1, CSF1R, RAC1, PTEN, PLK1, TGFB2, NRG1, BCL2L1, GAS6, BAX, TNFSF13B, SMAD4, PIM2, CSE1L, KLF10, IGSF8, IRS2, DLX5, ISG20, NANOG, NPY, UCN2, SRA1, PEMT |
| cell proliferation in bone marrow | biological_process | ACE |
| cell proliferation in forebrain | biological_process | WNT7A, EMX2 |
| cell proliferation in midbrain | biological_process | WNT2, WNT1 |
| cell proliferation involved in heart valve development | biological_process | TWIST1 |
| cell recognition | biological_process | PECAM1, VCAN, LAMA5, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
| cell redox homeostasis | biological_process | GCLC, TXN, NOS2, APEX1, NOS3, LTF, GPX1, IL6, NFE2L2, PTGES2 |
| cell surface receptor signaling pathway | biological_process | INHBA, MET, CRHR1, TNFRSF1A, CD36, IL12B, MIF, TNFSF10, CCR1, CCR5, CXCR3, TNFRSF1B, AGTR2, PRLR, LAMA1, IL1R1, CXCR1, CXCR2, CD79A, LEPR, CCL2, KLRC1, LIFR, TACR2, TACR1, CD82, FCER1G, OXTR, SSTR1, BSG, EGFR, IFNG, ANXA1, INHA, CXCL10, ERBB2, CD4, CCL25, FYN, CXCL13, C5, PRL, IL2RA, EDN1, AGER, KLRD1, TRPV1, SST, CRHR2, IL17A |
| cell-abiotic substrate adhesion | biological_process | ID1 |
| cell-cell adhesion | biological_process | EPCAM, MMP24 |
| cell-cell adhesion mediated by cadherin | biological_process | MMP24 |
| cell-cell adhesion mediated by integrin | biological_process | ITGB1 |
| cell-cell junction assembly | biological_process | CLDN5 |
| cell-cell junction maintenance | biological_process | CSF1R |
| cell-cell junction organization | biological_process | GJA1, TGFB1, RAC1, TGFB2, SMAD3 |
| cell-cell signaling | biological_process | TXN, INHBA, CCL5, FGFR2, GJA1, IL10, CCL3, AR, WNT2, TNFSF10, FASLG, CCR1, CCR5, IL15, IL11, EFNA1, BDNF, SSTR1, SRD5A2, NTF4, IL13, ADM, CXCL5, GREM1, INHA, NGF, CXCL10, PDGFA, CCL21, CYR61, CCL22, NRP1, CCL16, CXCL13, PGR, IL1B, CXCL14, ITGB2, CGA, LHB, GHRH, LTA, AMH, WNT1, EDN1, TGFB2, NR5A1, TEK, ESR2, IL18, PCSK5, KLF10, CCL7, IL2, SST, CXCL6, IHH, IL17A, IL22, CCL17, GDF15, CCL27 |
| cell-matrix adhesion | biological_process | ITGA6, ITGA3, CTNNB1, ITGA2, ITGB5, CD44, VCAM1, ITGB6, FN1, ITGB3, ITGB1, ITGAV, FGA, BCL2L11, ITGB2, RAC1, HPSE, MUC4 |
| cell-substrate adhesion | biological_process | ITGA6, ITGA2, ITGB3, ITGB1, ITGAV, GAS6, ANGPT1 |
| cell-substrate junction assembly | biological_process | ITGA6, FN1, ITGB3 |
| cellular aldehyde metabolic process | biological_process | ALDH3A2 |
| cellular amino acid biosynthetic process | biological_process | ADI1, FOLH1 |
| cellular amino acid metabolic process | biological_process | MTHFR |
| cellular aromatic compound metabolic process | biological_process | CYP1A2, EPHX1, CYP1B1 |
| cellular biogenic amine metabolic process | biological_process | MAOA |
| cellular calcium ion homeostasis | biological_process | BCL2, CCL5, CCL3, DRD2, CCR1, VDR, CD40, CCL2, CCR2, CXCL12, ITGB1, TGFB1, PRKCB, APOE, STOML2, CCL19, CCL7, CCL11, STC1 |
| cellular chloride ion homeostasis | biological_process | FASLG |
| cellular component disassembly involved in execution phase of apoptosis | biological_process | CASP3, PTK2 |
| cellular copper ion homeostasis | biological_process | CCDC22, ATP7A |
| cellular defense response | biological_process | CCR5, CXCR2, HLA-G, CCR2, CCR9, ITGB1, NCR1, IL4, RELA |
| cellular detoxification of nitrogen compound | biological_process | GSTM1 |
| cellular developmental process | biological_process | PRDM1 |
| cellular extravasation | biological_process | TNF, ITGB2 |
| cellular glucose homeostasis | biological_process | PIK3R1, FOXO1, SIRT1 |
| cellular heat acclimation | biological_process | HSPA6 |
| cellular homeostasis | biological_process | CCL2, CCR2, MCL1, MUC17 |
| cellular hyperosmotic response | biological_process | ERRFI1 |
| cellular iron ion homeostasis | biological_process | HMOX1, BMP6, HMOX2, SOD1, MYC, CP, TF, HPX, HIF1A, SMAD4, ABCG2, HAMP |
| cellular ketone metabolic process | biological_process | CYP2B6 |
| cellular lipid metabolic process | biological_process | STAR, PPARA |
| cellular oxidant detoxification | biological_process | PRDX6, GPX3, LPO, PTGS1, GSTT1, PTGS2, GSTZ1, APOE, GPX1, HP, CAT, PARK7 |
| cellular process | biological_process | CTNNB1, JUN |
| cellular process regulating host cell cycle in response to virus | biological_process | BCL2L11, BCL2L1 |
| cellular protein catabolic process | biological_process | CHEK2 |
| cellular protein complex assembly | biological_process | CCL5, FGA, MBD2 |
| cellular protein complex disassembly | biological_process | NRG1 |
| cellular protein complex localization | biological_process | SMAD7 |
| cellular protein localization | biological_process | WNT5A, CTNNB1, CTNNA1, TP53, LATS1, CDC42 |
| cellular protein metabolic process | biological_process | MMP13, IGFBP2, IGFBP3, CSF2RB, IGFBP5, IGFBP1, SAA1, IGFBP4, IGF1, FGA, APOA1, LTF, PRL, IGF2, APCS, MMP1, KLK3, MMP2, CTSG, HIST2H3A, GATA6, PAPPA, SFTPA1 |
| cellular protein modification process | biological_process | AKT1, PLAT |
| cellular respiration | biological_process | NDUFS1, CYP1A2, BAX |
| cellular response to alkaloid | biological_process | STAR, ICAM1, BCL2L1, TRPV1 |
| cellular response to alkyl hydroperoxide | biological_process | CCL5 |
| cellular response to amino acid starvation | biological_process | CDKN1A |
| cellular response to amino acid stimulus | biological_process | DNMT1, CCL5, ZEB1, EGFR, TNF, COL4A1, COL5A2, MMP2, BCL2L1, DNMT3A, NTRK2 |
| cellular response to antibiotic | biological_process | PLA2G4A, CDKN1B, STAR, CYP17A1, IL1B |
| cellular response to arsenic-containing substance | biological_process | HMOX1 |
| cellular response to ATP | biological_process | CCL2, PTGS2, SOD1, TRPV1 |
| cellular response to bacterial lipopeptide | biological_process | CD36, TLR2 |
| cellular response to bisphenol A | biological_process | CHEK2 |
| cellular response to BMP stimulus | biological_process | GATA3, BMP4, BMP6, FN1, BMPR1B, SMAD4, GATA6, DLX5, GATA5 |
| cellular response to brain-derived neurotrophic factor stimulus | biological_process | NFKB1, NTRK2 |
| cellular response to cadmium ion | biological_process | HMOX1, AKR1C3, STAR, SOD1, CYP1A2, OGG1 |
| cellular response to calcium ion | biological_process | WNT5A, ALOX15, BRAF, CRHBP, AKR1C3, JUN, FOS, EDN1 |
| cellular response to cAMP | biological_process | CFTR, APEX1, IGFBP5, CRHBP, WT1, STAR, AQP8, ADIPOQ, SRD5A1, STC1 |
| cellular response to carbohydrate stimulus | biological_process | NFKB1, PRKCB |
| cellular response to carbon monoxide | biological_process | HIF1A |
| cellular response to cell-matrix adhesion | biological_process | GSTP1 |
| cellular response to cGMP | biological_process | SLC6A4 |
| cellular response to cholesterol | biological_process | INHBA |
| cellular response to cobalt ion | biological_process | SERPINF1, FAS, HIF1A |
| cellular response to cocaine | biological_process | CRHBP, CRH |
| cellular response to cold | biological_process | FOXO1 |
| cellular response to copper ion | biological_process | AQP2 |
| cellular response to corticosteroid stimulus | biological_process | AKR1C3 |
| cellular response to corticotropin-releasing hormone stimulus | biological_process | CRHR1, CRHR2 |
| cellular response to cortisol stimulus | biological_process | KLF9 |
| cellular response to cyanide | biological_process | HIF1A |
| cellular response to cytokine stimulus | biological_process | GATA3, STAT3, MME, CCL5, FAS, FLT3, IL13, FGA, CSF1R, CXCR4, CCR7 |
| cellular response to decreased oxygen levels | biological_process | AKT1, PTEN |
| cellular response to dexamethasone stimulus | biological_process | SERPINF1, AGTR2, CCL2, STAR, TGFB1, MSTN, IL6, CRH, FOXO1, ERRFI1, DNMT3B, ABCG2, SRD5A1 |
| cellular response to diacyl bacterial lipopeptide | biological_process | CD36, TLR2 |
| cellular response to diterpene | biological_process | NFKB1 |
| cellular response to DNA damage stimulus | biological_process | MSH2, MSH6, H2AFX, MLH1, BCL2, YAP1, CCND1, BCL6, PCNA, MAPK1, HMGB1, APEX1, AKT1, ATF2, BRCA1, CASP3, CDKN1A, XRCC1, BRCA2, CTLA4, CHEK2, XRCC3, CLOCK, TP53, SUV39H1, MYC, SGK1, XRCC4, FOXO1, BAX, SIRT1, ATM, TP63, MICA, PMS2, OGG1 |
| cellular response to dopamine | biological_process | GSK3B, ID1, HDAC2 |
| cellular response to drug | biological_process | NOS2, NME1, BRAF, CRHBP, CCL2, CHEK2, TP53, MYC, TLR3, IL1B, EDN1, HIF1A, GAS6, ADIPOQ, NFE2L2, ESR2, AGER, CD69 |
| cellular response to dsRNA | biological_process | NFKB1, TLR3 |
| cellular response to electrical stimulus | biological_process | IGF1, HIF1A |
| cellular response to epidermal growth factor stimulus | biological_process | AKT1, ID1, GSTP1, TDGF1, EGFR, ERRFI1, PAX2 |
| cellular response to epinephrine stimulus | biological_process | STAR, ADIPOQ, SRD5A1 |
| cellular response to erythropoietin | biological_process | GSK3B |
| cellular response to estradiol stimulus | biological_process | IL10, ITGA2, CRHBP, SSTR1, ESR1, IGF1, EGFR, ESR2, GPER1, SRD5A1 |
| cellular response to estrogen stimulus | biological_process | CRHBP, FAS, ESR1 |
| cellular response to ethanol | biological_process | CCL5, DNMT3A, CCL7 |
| cellular response to exogenous dsRNA | biological_process | TLR3 |
| cellular response to extracellular stimulus | biological_process | ITGA6, CDKN1A, AXL, FOS, AIF1 |
| cellular response to fatty acid | biological_process | SRC, CCNB1, NME1, IL1B, EDN1, AGER |
| cellular response to fibroblast growth factor stimulus | biological_process | CCL5, CXCL8, CTNNB1, CD44, TDGF1, CCL2, STAR, DLL4, POSTN |
| cellular response to fluid shear stress | biological_process | SRC, MMP13, PTGS2, CA2, PLAU, NFE2L2 |
| cellular response to folic acid | biological_process | FOLR1 |
| cellular response to follicle-stimulating hormone stimulus | biological_process | INHBA, NOTCH1, STAR |
| cellular response to forskolin | biological_process | PTGER3 |
| cellular response to gamma radiation | biological_process | H2AFX, EGR1, YAP1, CRYAB, BCL2L1, ATM |
| cellular response to glucocorticoid stimulus | biological_process | AHR, GSTP1, FLT3, SSTR5, ANXA1, EDN1, HEY1, CRHR2, IL17A, STC1, UCN2 |
| cellular response to glucose starvation | biological_process | BCL2, TP53, NFE2L2 |
| cellular response to glucose stimulus | biological_process | PTGER4, SERPINF1, NME1, LGALS1, IL1R1, FAS, PIK3CA, CMA1, STAR, FN1, IL1B, PLAU, ICAM1, HIF1A, GAS6, AGER, GPER1, PAX2, IRS2, CPB2 |
| cellular response to glucoside | biological_process | NFKB1 |
| cellular response to glyoxal | biological_process | PARK7 |
| cellular response to gonadotropin stimulus | biological_process | WT1, LHCGR, STAR, CYP17A1, GATA6 |
| cellular response to gonadotropin-releasing hormone | biological_process | ANXA5, CRHBP |
| cellular response to granulocyte colony-stimulating factor | biological_process | FGA |
| cellular response to granulocyte macrophage colony-stimulating factor stimulus | biological_process | MAPK1, AKT1 |
| cellular response to growth factor stimulus | biological_process | BMP4, CLU, AKT1, SHC1, CTNNB1, TNFRSF1B, SPARC, INSR, TGFB1, ERBB2, FYN, ANGPT2, CAT, GAS6, TWIST1, SRD5A1 |
| cellular response to growth hormone stimulus | biological_process | STAR |
| cellular response to heat | biological_process | CDKN1A, HSPA6, HMOX1, MKI67, FGF1, IL1A, CXCL10, PDCD6, THBS1, HDAC2, HSF1 |
| cellular response to heparin | biological_process | EGR1 |
| cellular response to hepatocyte growth factor stimulus | biological_process | GSK3B, IL10, HGF, TDGF1, NRP1, PLAU, IL6, RELA |
| cellular response to high density lipoprotein particle stimulus | biological_process | CCL5, CCL2 |
| cellular response to hormone stimulus | biological_process | STAT3, IGFBP2, LIPC, OXTR, JUN, FOS, AIF1 |
| cellular response to hydrogen peroxide | biological_process | GSK3B, AKR1B1, APEX1, F3, FAS, STAT6, ANXA1, IL6, HDAC2, RELA, PARK7, HIF1A, FOXO1, NFE2L2, EZH2, SIRT1, AGER, PAX2, CYP1B1 |
| cellular response to hydroperoxide | biological_process | CD36, AIF1 |
| cellular response to hydrostatic pressure | biological_process | FAS |
| cellular response to hyperoxia | biological_process | PPARG, FAS, FOXO1, DNMT3B |
| cellular response to hypoxia | biological_process | BCL2, SRC, VEGFA, AKT1, CCNB1, HMOX1, FAS, PTN, MTOR, PTGS2, TP53, SUV39H1, TERT, PLAU, ICAM1, EDN1, PTEN, DNMT3A, HIF1A, EIF4EBP1, SIRT1, TWIST1, ADAM8, GATA6, SUV39H2, STC1, UCN2 |
| cellular response to indole-3-methanol | biological_process | CDH1, CTNNB1, BRCA1, CTNNA1 |
| cellular response to insulin stimulus | biological_process | SRC, PPARG, PIK3R1, AKT1, SHC1, GSTP1, USF1, CCL2, STAR, INSR, IGF1, HIF1A, FOXO1, PAK1, ADIPOQ, KAT2B, ERRFI1, IRS2, SRD5A1 |
| cellular response to insulin-like growth factor stimulus | biological_process | CTNNB1 |
| cellular response to interferon-alpha | biological_process | GATA3, AXL, STAR, GAS6 |
| cellular response to interferon-beta | biological_process | TLR3 |
| cellular response to interferon-gamma | biological_process | NOS2, WNT5A, CCL5, IL12B, CCL3, TDGF1, CCL2, MRC1, STAR, LGALS9, CCL25, CCL21, CCL22, TLR3, CCL16, EDN1, AIF1, CCL19, DAPK1, CCL7, CX3CL1, CCL17, CCL11 |
| cellular response to interleukin-1 | biological_process | CCL5, CHI3L1, CXCL8, PTGER4, CCL3, NFKB1, FAS, CCL2, PTGER3, FN1, CCL25, CCL21, CCL22, CCL16, ICAM1, IL6, EDN1, RELA, HIF1A, CCL19, CCL7, CX3CL1, IL17A, CCL17, CCL11 |
| cellular response to interleukin-13 | biological_process | ALOX15 |
| cellular response to interleukin-18 | biological_process | IFNG |
| cellular response to interleukin-3 | biological_process | GSK3B, CSF2RB |
| cellular response to interleukin-4 | biological_process | GATA3, MRC1, IL24 |
| cellular response to interleukin-6 | biological_process | NFKB1, TDGF1, CCL2, FGA, RELA |
| cellular response to ionizing radiation | biological_process | CDKN1A, ITGB1, CLOCK, TP53, SIRT1 |
| cellular response to iron ion | biological_process | BMP6, TF |
| cellular response to iron(II) ion | biological_process | GSK3B |
| cellular response to iron(III) ion | biological_process | CCNB1 |
| cellular response to jasmonic acid stimulus | biological_process | AKR1C3, AKR1C2, AKR1C1 |
| cellular response to L-ascorbic acid | biological_process | LEP |
| cellular response to laminar fluid shear stress | biological_process | NFE2L2 |
| cellular response to lead ion | biological_process | DNMT1, ANXA5 |
| cellular response to leptin stimulus | biological_process | STAT3, LEP |
| cellular response to light stimulus | biological_process | HIF1A |
| cellular response to lipid | biological_process | CCL5, IL1B, HIF1A |
| cellular response to lipopolysaccharide | biological_process | SRC, NOS2, WNT5A, CCL5, CD36, IL10, IL12B, CXCL8, NFKB1, CCR5, TNFRSF1B, CD40, AXL, GSTP1, CCL2, MRC1, IL12A, PTGER3, STAR, FN1, CYP17A1, IFNG, TNF, CXCL10, TLR4, SERPINE1, IL1B, PLAU, ICAM1, CSF2, IL6, RELA, HIF1A, IL24, CXCL16, KLRK1, LILRB1 |
| cellular response to lipoprotein particle stimulus | biological_process | CCL2 |
| cellular response to lipoteichoic acid | biological_process | CD36, TLR2, TLR4 |
| cellular response to lithium ion | biological_process | GSK3B, CDH1, CTNNB1, CDKN1B, FAS, XRCC4, ID2 |
| cellular response to low-density lipoprotein particle stimulus | biological_process | CD36, FCER1G, ITGB1, ITGB2 |
| cellular response to luteinizing hormone stimulus | biological_process | STAR |
| cellular response to macrophage colony-stimulating factor stimulus | biological_process | CCL2, CSF1R |
| cellular response to magnetism | biological_process | ESR2 |
| cellular response to mechanical stimulus | biological_process | GSK3B, BMP4, TNFRSF1A, GJA1, AKT1, CTNNB1, PTGER4, NFKB1, CASP1, CD40, EDNRA, ITGA2, MMP7, FAS, BMP6, IL13, PTGS2, ITGB1, TLR4, TLR3, CTSB, IL1B, IGF2, RAC1, HIF1A |
| cellular response to mercury ion | biological_process | AQP2, FN1, IL4 |
| cellular response to metal ion | biological_process | HSD17B1, STAR, FSTL3 |
| cellular response to methotrexate | biological_process | IL1B |
| cellular response to methylglyoxal | biological_process | AKR1B1 |
| cellular response to mineralocorticoid stimulus | biological_process | EDN1, GPER1 |
| cellular response to molecule of bacterial origin | biological_process | WNT5A |
| cellular response to morphine | biological_process | CCL5, OPRM1, AIF1 |
| cellular response to muramyl dipeptide | biological_process | NOD2, NOD1, PTPN22 |
| cellular response to mycophenolic acid | biological_process | EGR1 |
| cellular response to nerve growth factor stimulus | biological_process | DNMT1, AKT1, ID1, NTRK2 |
| cellular response to nicotine | biological_process | NFKB1, TNF, RELA |
| cellular response to nitric oxide | biological_process | MMP3, FOXO1 |
| cellular response to nitrite | biological_process | HIF1A |
| cellular response to nitrogen starvation | biological_process | GABARAPL1 |
| cellular response to nitrosative stress | biological_process | ATM |
| cellular response to nutrient | biological_process | HMOX1 |
| cellular response to nutrient levels | biological_process | MTOR, ICAM1, UCN2 |
| cellular response to organic cyclic compound | biological_process | STAT3, CCL5, AKT1, CCNB1, CCL3, NFKB1, CDKN1B, CASP3, IGFBP5, ITGA2, LGALS1, FAS, CCL2, PTN, STAR, TGFB1, FGA, TNF, IL1B, PAK4, CYP1A1, HIF1A, ESR2, IL18, AGER, CYP1B1, SRD5A1 |
| cellular response to organic substance | biological_process | BCL2, EGR1, CCND1, MAPK1, SLC6A4, CASP1, CASP3, TIMP3, IL1B, PLAU, ICAM1, PSAP, SYP, BAX, TBX21 |
| cellular response to organonitrogen compound | biological_process | APEX1 |
| cellular response to oxidative stress | biological_process | BMP4, SOD1, GPX1, PARK7, FOXO1, NFE2L2, KAT2B |
| cellular response to parathyroid hormone stimulus | biological_process | KAT2B |
| cellular response to peptide | biological_process | AKR1B1, AKT1, NFKB1, ID1, IL1RL1, KLF10, IRS2 |
| cellular response to peptide hormone stimulus | biological_process | SRC, APEX1, NFKB1, CYP11A1, FYN, WNT1, EDN1, RELA, GPER1 |
| cellular response to phenylalanine | biological_process | FAS |
| cellular response to phosphate starvation | biological_process | COMT |
| cellular response to platelet-derived growth factor stimulus | biological_process | SRC, DNMT1, CCL2, PTN, FN1, FYN, ERRFI1 |
| cellular response to potassium ion | biological_process | CRHBP, SOD1 |
| cellular response to potassium ion starvation | biological_process | JUN |
| cellular response to progesterone stimulus | biological_process | SRC |
| cellular response to prostaglandin D stimulus | biological_process | TNC, AKR1C3, PTGFR, AKR1C2 |
| cellular response to prostaglandin E stimulus | biological_process | PPARG, AKT1, PTGER4, PTGER2, FN1 |
| cellular response to prostaglandin stimulus | biological_process | PPARG, AKR1C3 |
| cellular response to reactive nitrogen species | biological_process | STAT6 |
| cellular response to reactive oxygen species | biological_process | SRC, PDGFRA, AKR1C3, FOS, PARK7 |
| cellular response to retinoic acid | biological_process | YAP1, WNT5A, PPARG, LEP, SERPINF1, SLC6A4, WNT2, CCL2, TNC, HDAC2, PAX2 |
| cellular response to sorbitol | biological_process | MAP2K7 |
| cellular response to starvation | biological_process | AKR1C3, FOXO1, GAS6, SIRT1, EHMT2, KLF10, WNT4, SRD5A1 |
| cellular response to staurosporine | biological_process | PLAU |
| cellular response to steroid hormone stimulus | biological_process | NR3C1 |
| cellular response to stress | biological_process | OPRM1, CRHBP |
| cellular response to testosterone stimulus | biological_process | SRD5A1 |
| cellular response to thyroid hormone stimulus | biological_process | BMP4, KIT, CTSB, KLF9 |
| cellular response to toxic substance | biological_process | HIF1A |
| cellular response to transforming growth factor beta stimulus | biological_process | SRC, DNMT1, WNT5A, CCL5, WNT2, ID1, COL4A2, STAR, FN1, TGFB1, FYN, SMAD7, WNT7A, EDN1, PTK2, HDAC2, WNT4, POSTN |
| cellular response to triacyl bacterial lipopeptide | biological_process | TLR2 |
| cellular response to tumor necrosis factor | biological_process | GATA3, CCL5, CHI3L1, CXCL8, BRCA1, CCL3, NFKB1, CRHBP, FAS, TDGF1, CCL2, VCAM1, CCL25, CCL21, CCL22, CCL16, TNFRSF21, ICAM1, IL6, EDN1, RELA, NTRK2, NFE2L2, CCL19, SIRT1, GPER1, CCL7, CX3CL1, POSTN, CCL17, CCL11 |
| cellular response to UV | biological_process | PCNA, PIK3R1, PTN, PTGS2, TP53, MYC, BAX, TP63 |
| cellular response to UV-A | biological_process | MME |
| cellular response to UV-B | biological_process | MME, CDKN1A |
| cellular response to vascular endothelial growth factor stimulus | biological_process | VEGFA, AKT1, NOTCH1, KDR, FLT4, FLT1, VCAM1, FN1, HSPB1, NRP1, DLL4 |
| cellular response to virus | biological_process | IL12A, LGALS9, CCL19 |
| cellular response to vitamin D | biological_process | IL15, PTN, TNC, ITGB1 |
| cellular response to vitamin E | biological_process | PPARG |
| cellular response to vitamin K | biological_process | CCL5, GAS6, POSTN |
| cellular response to water deprivation | biological_process | AQP2 |
| cellular response to xenobiotic stimulus | biological_process | RB1 |
| cellular senescence | biological_process | H2AFX, CDKN1A, CDKN2A, ID2 |
| cellular sodium ion homeostasis | biological_process | AGTR2, SGK1 |
| cellular triglyceride homeostasis | biological_process | SIRT1 |
| cellular water homeostasis | biological_process | AQP2, AQP8, AQP5 |
| central nervous system development | biological_process | SRC, GSTP1, VCAN, TIMP2, TIMP3, ZEB1, ALDH3A2, FYN, PTEN, ADAM22, TIMP4 |
| central nervous system morphogenesis | biological_process | WNT1 |
| central nervous system myelin maintenance | biological_process | CLU, PTEN |
| central nervous system myelination | biological_process | HES5 |
| central nervous system neuron axonogenesis | biological_process | PTEN, PTK2 |
| central nervous system neuron development | biological_process | FGFR1, LEP, GATA2, MAP2, NTRK2, ATP7A, NPY |
| central nervous system vasculogenesis | biological_process | CTNNB1, ENG, WNT7A |
| centrosome cycle | biological_process | BRCA1 |
| centrosome duplication | biological_process | BRCA2 |
| centrosome localization | biological_process | AURKA |
| centrosome organization | biological_process | AURKA, PLK1 |
| cerebellar cortex development | biological_process | AGTR2, EZH2 |
| cerebellar granular layer development | biological_process | MDK |
| cerebellar granule cell differentiation | biological_process | WNT7A |
| cerebellar Purkinje cell differentiation | biological_process | ATP7A |
| cerebellar Purkinje cell layer development | biological_process | NAGLU |
| cerebellum development | biological_process | PTN, SSTR1, WNT1, ESR2, CRHR2 |
| cerebellum formation | biological_process | WNT1 |
| cerebral cortex cell migration | biological_process | EGFR |
| cerebral cortex development | biological_process | H2AFX, MDK, NTRK2, HIF1A, BAX, PLCB1, EMX2, NPY, SRD5A1 |
| cerebral cortex GABAergic interneuron development | biological_process | RAC1 |
| cerebral cortex GABAergic interneuron migration | biological_process | DRD2 |
| cerebral cortex neuron differentiation | biological_process | CHD5 |
| cerebral cortex radially oriented cell migration | biological_process | RAC1 |
| cerebral cortex regionalization | biological_process | EMX2 |
| cervix development | biological_process | WNT5A |
| cGMP-mediated signaling | biological_process | CD36, APOE |
| chaperone mediated protein folding requiring cofactor | biological_process | CD74 |
| chaperone-mediated autophagy | biological_process | HSP90AA1 |
| chaperone-mediated protein complex assembly | biological_process | HSPD1, CLU, HSPA4, HSP90AA1, APCS |
| chaperone-mediated protein folding | biological_process | CLU, FKBP4, FKBP5 |
| chemical synaptic transmission | biological_process | MAPK1, OPRM1, CTNNB1, SLC6A4, TACR2, TACR1, SLC6A2, SSTR1, SSTR5, NPTX2, SNCG, CRH, P2RX3, SST, PLCB3, LPAR3, NPY |
| chemical synaptic transmission, postsynaptic | biological_process | GSK3B, AKT1, DRD2 |
| chemoattraction of serotonergic neuron axon | biological_process | WNT5A |
| chemokine (C-C motif) ligand 11 production | biological_process | CXCR3 |
| chemokine (C-C motif) ligand 19 signaling pathway | biological_process | CCR7 |
| chemokine (C-C motif) ligand 2 secretion | biological_process | FOXP1, F2RL1 |
| chemokine (C-C motif) ligand 21 signaling pathway | biological_process | CCR7 |
| chemokine biosynthetic process | biological_process | IL18 |
| chemokine secretion | biological_process | F2RL1 |
| chemokine-mediated signaling pathway | biological_process | CCL5, CXCL8, CCL3, CCR1, CCR5, CXCR3, CXCL1, CXCR1, CXCR2, CCL2, CXCL2, CCR2, CXCL5, CXCL12, CCR9, CXCL10, CCL25, CXCR6, CCL21, CCL22, CCL16, CXCL13, CXCR4, CCL19, CCL7, CX3CL1, CXCL6, CCL17, CCR7, CCL11, CCR8 |
| chemokinesis | biological_process | PTGER4 |
| chemorepulsion involved in interneuron migration from the subpallium to the cortex | biological_process | NRG1 |
| chemorepulsion of dopaminergic neuron axon | biological_process | WNT5A |
| chemosensory behavior | biological_process | TRPV1 |
| chemotaxis | biological_process | FGF2, CCL5, MAPK1, HMGB1, CXCL8, CCL3, FPR1, CCR1, CCR5, CXCR3, PDGFRA, FLT1, CXCL1, CXCR1, CXCR2, CCL2, CXCL2, TYMP, L1CAM, CCR2, CXCL5, CXCL12, CCR9, CXCL10, LGALS9, CCL25, CXCR6, CCL21, CYR61, CCL22, DEFB4A, CCL16, CXCL13, CXCL14, PLAU, C5, IL4, RAC1, PLAUR, CXCR4, CCL19, RARRES2, CCL7, CX3CL1, DEFB1, CXCL6, IL16, CCL17, CXCL16, CCL27, CCR7, CCL11, CCR8 |
| chitin catabolic process | biological_process | CHI3L1, OVGP1 |
| chloride transmembrane transport | biological_process | CFTR, CLCN3, SLC26A8 |
| chloride transport | biological_process | CFTR, CLCN3, SLC26A8 |
| cholangiocyte proliferation | biological_process | MKI67 |
| cholesterol biosynthetic process | biological_process | CFTR, APOA1, ACLY, HSD17B7 |
| cholesterol catabolic process | biological_process | AKR1D1, APOE, SCARB1 |
| cholesterol efflux | biological_process | APOA1, APOA2, APOE, SCARB1 |
| cholesterol homeostasis | biological_process | CETP, LIPC, APOA1, APOA2, APOE, NR5A2, SIRT1, SCARB1, AKR1C1 |
| cholesterol import | biological_process | CD36, APOA1, SCARB1 |
| cholesterol metabolic process | biological_process | CETP, LEP, LIPC, LEPR, PON1, STAR, CYP11A1, APOA1, APOA2, APOE, CAT, IL4, NR0B2 |
| cholesterol transport | biological_process | CETP, CFTR, CD36, LIPC, APOA1, APOA2, SCARB1 |
| choline metabolic process | biological_process | BCHE |
| chondroblast differentiation | biological_process | FGF2, CYR61 |
| chondrocyte development | biological_process | BMPR1B |
| chondrocyte differentiation | biological_process | FGFR1, BMP4, HMGA2, TGFB1, BMPR1B, WNT7A, RUNX3, HES5 |
| chondrocyte proliferation | biological_process | HMGA2, MMP14, STC1 |
| chondroitin sulfate biosynthetic process | biological_process | BGN, VCAN, XYLT2, DCN |
| chondroitin sulfate catabolic process | biological_process | BGN, VCAN, DCN |
| chondroitin sulfate proteoglycan biosynthetic process | biological_process | XYLT2 |
| chordate embryonic development | biological_process | FGFR1, BRCA1, BRCA2, FAS |
| chorio-allantoic fusion | biological_process | CYR61 |
| chorionic trophoblast cell differentiation | biological_process | HTRA1 |
| chromatin assembly | biological_process | HMGB1, TP53 |
| chromatin assembly or disassembly | biological_process | SUV39H2 |
| chromatin organization | biological_process | HMGA2, SOX2, SUV39H1, ARID1A, SOX15, EZH2, SIRT1 |
| chromatin remodeling | biological_process | GATA3, ESR1, MYC, RB1, ARID1A, HDAC2, KAT2B, HDAC1, FOXP3, TP63, SUV39H2 |
| chromatin silencing | biological_process | H2AFX, SIRT1 |
| chromatin silencing at rDNA | biological_process | SUV39H1, SIRT1, HIST2H3A, MBD2 |
| chromatin-mediated maintenance of transcription | biological_process | CTNNB1, ARID1A |
| chromosome breakage | biological_process | HMGA2, BRCA1, BRCA2 |
| chromosome condensation | biological_process | HMGA2, PRM1 |
| chromosome organization | biological_process | BRCA2, MYC |
| chromosome segregation | biological_process | BRCA1, BIRC5, NR3C1, CEP85 |
| chronic inflammatory response | biological_process | CCL5, GJA1, VCAM1, PTGES, THBS1, CXCL13, CCL11 |
| chronic inflammatory response to antigenic stimulus | biological_process | TNF, IL1B |
| chronological cell aging | biological_process | ENG, SERPINE1 |
| chylomicron remnant clearance | biological_process | LIPC, APOE |
| chylomicron remodeling | biological_process | LIPC |
| ciliary body morphogenesis | biological_process | JAG1 |
| ciliary neurotrophic factor-mediated signaling pathway | biological_process | IL6R, IL6ST, CNTF, LIFR |
| cilium assembly | biological_process | NOTCH1 |
| circadian behavior | biological_process | TP53 |
| circadian regulation of gene expression | biological_process | AHR, DRD2, HNF1B, CLOCK, HDAC2, PPARA, HDAC1, SIRT1, ID2 |
| circadian rhythm | biological_process | GSK3B, NOS2, LEP, SLC6A4, ID1, LIPC, FAS, STAR, JUN, CLOCK, CLDN4, SERPINE1, NTRK2, ADIPOQ, SIRT1, ID2, KLF10, PROK1, KLF9 |
| circadian sleep/wake cycle, REM sleep | biological_process | STAR, SRD5A1 |
| citrate metabolic process | biological_process | ACLY |
| Clara cell differentiation | biological_process | GATA6 |
| cleavage furrow formation | biological_process | RHOA |
| cloacal septation | biological_process | BMP4, TP63 |
| cocaine metabolic process | biological_process | BCHE |
| cochlea development | biological_process | PAX2 |
| cochlea morphogenesis | biological_process | WNT5A, ZEB1, RAC1, PAX2 |
| cochlear nucleus development | biological_process | BCL2 |
| cognition | biological_process | LHCGR, HLA-DRA |
| collagen catabolic process | biological_process | MMP13, MMP9, COL4A2, MMP7, MMP10, MMP14, MMP11, COL18A1, MMP12, CTSB, COL4A1, MMP1, CTSD, COL5A2, MMP2, MMP3 |
| collagen fibril organization | biological_process | MMP11, GREM1, ANXA2, COL5A2, TGFB2, ATP7A, CYP1B1 |
| collagen metabolic process | biological_process | ID1, HIF1A |
| collagen-activated signaling pathway | biological_process | ITGA2 |
| collateral sprouting | biological_process | BDNF |
| collecting duct development | biological_process | NOTCH1 |
| comma-shaped body morphogenesis | biological_process | HES5 |
| commissural neuron axon guidance | biological_process | VEGFA, NRP1 |
| commitment of neuronal cell to specific neuron type in forebrain | biological_process | GATA2 |
| common myeloid progenitor cell proliferation | biological_process | GSTP1, FLT3 |
| common-partner SMAD protein phosphorylation | biological_process | BMP4, TGFB1, SMAD2 |
| compartment pattern specification | biological_process | NOTCH1 |
| complement activation | biological_process | CLU, MBL2, C4A, C3, C5 |
| complement activation, alternative pathway | biological_process | C3, C5 |
| complement activation, classical pathway | biological_process | CLU, MBL2, C4A, C3, C5, C4BPA, C1QBP |
| complement activation, lectin pathway | biological_process | MBL2, KRT1 |
| conditioned taste aversion | biological_process | FOS |
| connective tissue growth factor biosynthetic process | biological_process | IL4 |
| connective tissue replacement involved in inflammatory response wound healing | biological_process | F2R, TGFB1, IL1A, HIF1A |
| contact inhibition | biological_process | YAP1 |
| convergent extension | biological_process | WNT5A |
| convergent extension involved in axis elongation | biological_process | WNT5A |
| convergent extension involved in organogenesis | biological_process | WNT5A |
| conversion of ds siRNA to ss siRNA | biological_process | DICER1 |
| conversion of ds siRNA to ss siRNA involved in RNA interference | biological_process | DICER1 |
| COPII vesicle coating | biological_process | FOLR1, SERPINA1, STX5 |
| copper ion export | biological_process | ATP7A |
| copper ion import | biological_process | ATP7A |
| copper ion transport | biological_process | CP, FKBP4, ATP7A |
| coronary artery morphogenesis | biological_process | VEGFA, NOTCH1, NRP1 |
| coronary vasculature development | biological_process | PRDM1, PCSK5 |
| coronary vein morphogenesis | biological_process | VEGFA, NOTCH1 |
| cortical actin cytoskeleton organization | biological_process | TNF |
| corticotropin secretion | biological_process | CRHR1 |
| cortisol metabolic process | biological_process | CYP11A1 |
| cortisol secretion | biological_process | GHRL |
| coumarin catabolic process | biological_process | CYP2A6 |
| coumarin metabolic process | biological_process | CYP2A6, CYP1A1 |
| cranial ganglion development | biological_process | CTNNB1 |
| cranial nerve development | biological_process | ERBB3 |
| cranial suture morphogenesis | biological_process | BMP4, TWIST1 |
| craniofacial suture morphogenesis | biological_process | MMP14 |
| CRD-mediated mRNA stabilization | biological_process | YBX1 |
| creatinine metabolic process | biological_process | MME |
| CTP biosynthetic process | biological_process | NME1 |
| cullin deneddylation | biological_process | COPS5 |
| cyclooxygenase pathway | biological_process | PTGDS, PTGS1, PTGS2, AKR1C3, PTGES |
| cysteine metabolic process | biological_process | GCLC |
| cytokine biosynthetic process | biological_process | PCSK5, IL17F |
| cytokine production | biological_process | CD4, FOXP3, MAF |
| cytokine production involved in immune response | biological_process | NOD2 |
| cytokine production involved in inflammatory response | biological_process | IDO1 |
| cytokine secretion | biological_process | S100A13 |
| cytokine secretion involved in immune response | biological_process | TLR2, NOD2 |
| cytokine-mediated signaling pathway | biological_process | STAT3, TNFRSF1A, BGN, F3, KIT, IL12B, CCR1, CSF2RB, IL6R, IL6ST, IL1R1, CCL2, IL2RB, LIFR, STAT6, IL1R2, FLT3, CCR2, IL1A, SOCS3, IL1B, KRAS, IL5, IL6, CSF1R, RELA, CX3CL1, IL10RB, IL22RA1, IL11RA, IL20RB, IL1RAP, IL37, IL20RA, DCN |
| cytokinesis | biological_process | BRCA2, RHOC, BIRC5, PLK1, BCL2L1 |
| cytolysis | biological_process | C5, MICA, MICB |
| cytoplasmic sequestering of NF-kappaB | biological_process | IL10, CCDC22, PSMD10 |
| cytoplasmic sequestering of protein | biological_process | LATS1 |
| cytosine metabolic process | biological_process | MAPK1, TET2 |
| cytoskeleton organization | biological_process | CFL1, CCL3, CCL2, APOE, LAMA5, PAK4, RAC1, DPYSL2, CCL7, KISS1, CCL11 |
| dATP catabolic process | biological_process | ADA |
| daunorubicin metabolic process | biological_process | AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
| death-inducing signaling complex assembly | biological_process | TNFRSF1A, TNF |
| decidualization | biological_process | PLA2G4A, SPP1, VDR, LIF, PTGS2, BSG, ESR1, CTSB, GHRL, STC1 |
| defecation | biological_process | MDK |
| defense response | biological_process | GATA3, INHBA, TNFRSF1A, TNF, DEFB4A, TLR3, HP, CD74, MPO, RELA, HSF1, NOD2, MST1R, NOD1, TPSAB1, CX3CL1, DEFB1, CD83, TFF3 |
| defense response to bacterium | biological_process | NOS2, TNFRSF1A, IL10, MBL2, LPO, FCER1G, CCR2, IFNG, LTF, TNF, TLR4, SLPI, DEFB4A, TLR3, CXCL13, HP, CTSG, TLR9, NOD2, NOD1, MICA, DEFB1, CXCL6, HAMP |
| defense response to fungus | biological_process | MPO, CTSG, HAMP, IL17A |
| defense response to fungus, incompatible interaction | biological_process | TGFB1 |
| defense response to Gram-negative bacterium | biological_process | NOS2, IL12B, IL6R, SELP, ADM, TLR4, CD4, SERPINE1, IL6, TLR9, IL23A, IL22RA1, NPY |
| defense response to Gram-positive bacterium | biological_process | CD36, MBL2, IL6R, HLA-E, PLA2G2A, IL12A, ADM, ANG, TNF, TLR2, CRP, LTA, IL6, CTSG, NOD1, ADAM17, DEFB1, NPY, KLRK1 |
| defense response to protozoan | biological_process | IL10, IL12B, CD40, IL12A, IFNG, IL4, IL6 |
| defense response to virus | biological_process | BCL2, IL12B, CD40, IFNG, CXCL10, TLR3, IL33, IL6, RELA, F2RL1, MICA, IL23A, IL10RB, ISG20, LILRB1 |
| definitive hemopoiesis | biological_process | GATA2, MEIS1, TEK |
| deltoid tuberosity development | biological_process | BMP4 |
| demethylation | biological_process | CYP1A1 |
| dendrite development | biological_process | NRP1, RAC1, HDAC2, GHRL |
| dendrite morphogenesis | biological_process | MAP2, ITGB1, FYN, RAC1, SEMA3A |
| dendrite regeneration | biological_process | FAS |
| dendritic cell chemotaxis | biological_process | CCL5, HMGB1, CCR1, CCR5, CXCR1, CXCR2, CCR2, CCL21, CXCR4, CCL19, CCR7 |
| dendritic cell cytokine production | biological_process | KIT |
| dendritic cell dendrite assembly | biological_process | CCL21 |
| dendritic cell differentiation | biological_process | AXL, FLT3, CSF2, IL4, GAS6, LILRB1 |
| dendritic cell migration | biological_process | CDC42 |
| dendritic spine development | biological_process | PAK4 |
| dendritic spine maintenance | biological_process | ITGA3 |
| dendritic spine morphogenesis | biological_process | WNT7A, PTEN |
| dentate gyrus development | biological_process | MDK, PTEN, EMX2 |
| dentinogenesis | biological_process | HTRA1 |
| deoxyadenosine catabolic process | biological_process | ADA |
| dephosphorylation | biological_process | PON1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR, SGPP2 |
| depurination | biological_process | OGG1 |
| depyrimidination | biological_process | OGG1 |
| dermatan sulfate biosynthetic process | biological_process | BGN, VCAN, DCN |
| desensitization of G-protein coupled receptor protein signaling pathway | biological_process | PTGER3 |
| desmosome organization | biological_process | NECTIN1 |
| detection of abiotic stimulus | biological_process | TACR1 |
| detection of bacterium | biological_process | HLA-DRB1, HLA-A, NOD2, NOD1 |
| detection of biotic stimulus | biological_process | NOD2, NOD1 |
| detection of chemical stimulus involved in sensory perception of bitter taste | biological_process | AZGP1, LPO |
| detection of diacyl bacterial lipopeptide | biological_process | TLR2 |
| detection of fungus | biological_process | TLR4 |
| detection of hypoxia | biological_process | ENG |
| detection of lipopolysaccharide | biological_process | TLR4, SCARB1 |
| detection of mechanical stimulus involved in sensory perception | biological_process | IGF1 |
| detection of mechanical stimulus involved in sensory perception of pain | biological_process | ITGA2, FYN |
| detection of mechanical stimulus involved in sensory perception of sound | biological_process | KIT |
| detection of muramyl dipeptide | biological_process | NOD2 |
| detection of oxidative stress | biological_process | ADIPOQ |
| detection of stimulus | biological_process | CADM1 |
| detection of temperature stimulus involved in sensory perception of pain | biological_process | MMP24 |
| detection of triacyl bacterial lipopeptide | biological_process | TLR2 |
| detection of virus | biological_process | TLR3 |
| determination of adult lifespan | biological_process | MSH2, MSH6, TP53, ATM |
| determination of dorsal identity | biological_process | GREM1 |
| determination of left/right symmetry | biological_process | WNT5A, NOTCH1, PCSK5, NODAL |
| detoxification of copper ion | biological_process | PARK7, ATP7A |
| detoxification of mercury ion | biological_process | PARK7 |
| development of primary male sexual characteristics | biological_process | WNT5A |
| development of secondary sexual characteristics | biological_process | BAX |
| developmental growth | biological_process | BCL2, GATA3, LIPC, HOXA11, ADM, PSAP, SMAD3, SMAD2, SMAD4 |
| developmental pigmentation | biological_process | BCL2, KIT, BCL2L11 |
| developmental process | biological_process | COMT, CYP1A1, TP63, IL11RA |
| developmental process involved in reproduction | biological_process | CSF1 |
| diacylglycerol biosynthetic process | biological_process | ANG |
| diacylglycerol catabolic process | biological_process | APOA2 |
| diapedesis | biological_process | PECAM1 |
| diaphragm development | biological_process | WT1 |
| dibenzo-p-dioxin catabolic process | biological_process | CYP1A1 |
| dibenzo-p-dioxin metabolic process | biological_process | CCL5, SRD5A2, STAR, CYP17A1, CYP1A2, CYP1A1 |
| dichotomous subdivision of terminal units involved in salivary gland branching | biological_process | NRP1, SEMA3A, SEMA3C |
| diencephalon development | biological_process | WNT1 |
| digestion | biological_process | AKR1D1, SSTR1, AKR1C2, AKR1C1, SST, NPY, TFF3, UCN2 |
| digestive system development | biological_process | NODAL |
| digestive tract development | biological_process | GATA3, ITGA6, FGFR2, KIT, CCNB1, GATA2, OXTR, TGFB1, RB1, CYP1A1 |
| digestive tract morphogenesis | biological_process | BCL2, WNT5A, EGFR, AGR2, HIF1A, NODAL |
| distal tubule development | biological_process | NOTCH1, JAG1 |
| diterpenoid metabolic process | biological_process | STAR, CRH, SRD5A1 |
| DNA biosynthetic process | biological_process | TERT |
| DNA catabolic process, exonucleolytic | biological_process | ISG20 |
| DNA damage checkpoint | biological_process | H2AFX, CHEK2, CLOCK, ATM |
| DNA damage induced protein phosphorylation | biological_process | CHEK2, ATM |
| DNA damage response, detection of DNA damage | biological_process | PCNA, HMGA2 |
| DNA damage response, signal transduction by p53 class mediator | biological_process | MIF, TP53 |
| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | biological_process | PCNA, CCNB1, CDKN1B, CDKN1A, MUC1, CHEK2, AURKA, TP53, BAX, ATM |
| DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological_process | BRCA1, MUC1, BRCA2, TP53, TP63 |
| DNA demethylation | biological_process | APEX1, TET3, TET2, TET1 |
| DNA demethylation of male pronucleus | biological_process | TET3 |
| DNA double-strand break processing | biological_process | BRCA1, ATM |
| DNA duplex unwinding | biological_process | ANXA1 |
| DNA geometric change | biological_process | HMGB1 |
| DNA hypermethylation | biological_process | DNMT1 |
| DNA ligation involved in DNA repair | biological_process | HMGB1, XRCC4 |
| DNA metabolic process | biological_process | NME1, IGFBP4, MKI67 |
| DNA methylation | biological_process | DNMT1, FOS, DNMT3A, EZH2, EHMT2, DNMT3B, DNMT3L |
| DNA methylation involved in embryo development | biological_process | DNMT3A |
| DNA methylation involved in gamete generation | biological_process | DNMT3A |
| DNA methylation on cytosine | biological_process | DNMT1, DNMT3A |
| DNA methylation on cytosine within a CG sequence | biological_process | DNMT1, DNMT3A, DNMT3B |
| DNA packaging | biological_process | PRM1 |
| DNA recombination | biological_process | H2AFX, HMGB1, APEX1, BRCA1, BRCA2, XRCC3, XRCC4 |
| DNA repair | biological_process | MSH2, MSH6, H2AFX, MLH1, PCNA, HMGB1, APEX1, BRCA1, XRCC1, BRCA2, MTOR, CHEK2, XRCC3, XRCC4, SIRT1, ATM, PMS2, OGG1 |
| DNA replication | biological_process | PCNA, BRCA1, TYMP, IGF1, EGF, SET, SIRT1, ATM |
| DNA rewinding | biological_process | ANXA1 |
| DNA strand elongation | biological_process | TERT |
| DNA strand elongation involved in DNA replication | biological_process | PCNA |
| DNA strand renaturation | biological_process | ANXA1, TP53 |
| DNA synthesis involved in DNA repair | biological_process | BRCA1, BRCA2, XRCC3, SIRT1, ATM |
| DNA topological change | biological_process | HMGB1 |
| DNA unwinding involved in DNA replication | biological_process | HMGA1 |
| DNA-templated transcription, initiation | biological_process | TBPL2 |
| dopamine biosynthetic process | biological_process | AGTR2, TGFB2 |
| dopamine catabolic process | biological_process | MAOA, COMT |
| dopamine metabolic process | biological_process | DRD2, COMT, ATP7A |
| dopamine receptor signaling pathway | biological_process | GSK3B, DRD2 |
| dopamine uptake involved in synaptic transmission | biological_process | SLC6A2, PARK7 |
| dopaminergic neuron differentiation | biological_process | VEGFA, WNT5A, CTNNB1, FIGF, WNT1, RAC1, HIF1A |
| dorsal aorta morphogenesis | biological_process | HEY1, DLL4 |
| dorsal root ganglion development | biological_process | CTNNB1 |
| dorsal root ganglion morphogenesis | biological_process | NRP1 |
| dorsal/ventral axis specification | biological_process | CTNNB1 |
| dorsal/ventral neural tube patterning | biological_process | BMP4 |
| dorsal/ventral pattern formation | biological_process | CTNNB1, HOXB2, HOXA11, BMPR1B, WNT7A, EDN1 |
| dosage compensation by inactivation of X chromosome | biological_process | BRCA1 |
| double-strand break repair | biological_process | MSH2, H2AFX, BRCA1, BRCA2, CHEK2, XRCC4 |
| double-strand break repair via homologous recombination | biological_process | H2AFX, BRCA1, XRCC1, BRCA2, XRCC3, ATM |
| double-strand break repair via nonhomologous end joining | biological_process | H2AFX, MLH1, BRCA1, XRCC4, ATM, HIST3H3 |
| doxorubicin metabolic process | biological_process | AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
| drinking behavior | biological_process | UCN |
| drug catabolic process | biological_process | CYP1A2 |
| drug export | biological_process | ABCG2 |
| drug metabolic process | biological_process | CYP2A6, CYP2B6, CYP2C19, CYP2E1, CYP1A2, CYP1A1 |
| drug transmembrane transport | biological_process | ABCB1, ABCG2 |
| drug transport | biological_process | ABCG2 |
| ductus arteriosus closure | biological_process | HPGD, PTGER4 |
| ear development | biological_process | BCL2, GATA3, BCL2L11, DLX5 |
| early endosome to Golgi transport | biological_process | STX5 |
| eating behavior | biological_process | STAT3, LEP, OPRM1, UCHL1, TACR1, OXTR |
| ectoderm and mesoderm interaction | biological_process | TP63 |
| ectoderm development | biological_process | CTNNB1 |
| ectodermal cell differentiation | biological_process | ITGA6 |
| ectopic germ cell programmed cell death | biological_process | KIT, KITLG, IL1A, IL1B, BAX |
| elastic fiber assembly | biological_process | ATP7A |
| elastin biosynthetic process | biological_process | ATP7A |
| elastin metabolic process | biological_process | HIF1A |
| electron transport chain | biological_process | MT-CO2 |
| embryo development | biological_process | ATP5A1, TDGF1, NR5A2, LAMA5, TGFB2, PTK2, NRG1, NOTCH4 |
| embryo development ending in birth or egg hatching | biological_process | CYP1A1 |
| embryo implantation | biological_process | FBLN1, MMP9, SPP1, PRLR, LIF, PTGS2, BSG, SOD1, IL1B, PLAU, MMP2, FKBP4, PCSK5, TRO, IL11RA, STC1 |
| embryonic axis specification | biological_process | CTNNB1, WNT7A, WNT1 |
| embryonic brain development | biological_process | CTNNB1, WNT1 |
| embryonic camera-type eye formation | biological_process | TWIST1 |
| embryonic camera-type eye morphogenesis | biological_process | ZEB1 |
| embryonic cranial skeleton morphogenesis | biological_process | BMP4, FGFR2, CTNNB1, PDGFRA, MMP14, SMAD3, SMAD2, TWIST1, NODAL |
| embryonic digestive tract development | biological_process | CXCL8, TNF, ADA, TGFB2, RARRES2, PCSK5 |
| embryonic digestive tract morphogenesis | biological_process | FGFR2, PDGFRA, HNF1B, ID2 |
| embryonic digit morphogenesis | biological_process | BMP4, WNT5A, GJA1, CTNNB1, HOXA11, WNT7A, HDAC2, HDAC1, SMAD4, TWIST1, IHH |
| embryonic epithelial tube formation | biological_process | WNT4 |
| embryonic eye morphogenesis | biological_process | FOXL2 |
| embryonic foregut morphogenesis | biological_process | CTNNB1, SMAD3, SMAD2 |
| embryonic forelimb morphogenesis | biological_process | CTNNB1, HOXA11, WNT7A, TWIST1 |
| embryonic heart tube development | biological_process | GJA1, CTNNB1, NODAL |
| embryonic heart tube morphogenesis | biological_process | YAP1 |
| embryonic hemopoiesis | biological_process | GATA3, KIT, KDR, KITLG, HIF1A |
| embryonic hindlimb morphogenesis | biological_process | BMP4, MMP13, CTNNB1, NOTCH1, WNT7A, TWIST1 |
| embryonic limb morphogenesis | biological_process | FGFR1, BMP4, WNT5A, NOTCH1, HOXA10, HOXA11, GREM1, WNT7A, DKK1, TWIST1, TP63, DLX5 |
| embryonic lung development | biological_process | PDGFA |
| embryonic morphogenesis | biological_process | FGF2, BMP4, FLT1, HNF1B, ZEB1 |
| embryonic olfactory bulb interneuron precursor migration | biological_process | RAC1 |
| embryonic organ development | biological_process | GATA3, FGFR2 |
| embryonic organ morphogenesis | biological_process | FGFR2 |
| embryonic pattern specification | biological_process | FGFR2, SMAD3, SMAD2, NODAL |
| embryonic placenta development | biological_process | GATA2, ARNT, EGFR, PRDM1, CSF2, HIF1A, HSF1, NODAL |
| embryonic process involved in female pregnancy | biological_process | HSF1, ABCG2, NODAL |
| embryonic skeletal joint morphogenesis | biological_process | BMP4, HOXA11 |
| embryonic skeletal limb joint morphogenesis | biological_process | CTNNB1 |
| embryonic skeletal system development | biological_process | BMP4, WNT5A, PCSK5 |
| embryonic skeletal system morphogenesis | biological_process | BMP4, PDGFRA, HOXB2, ZEB1, TWIST1 |
| enamel mineralization | biological_process | FOXO1, PPARA, NECTIN1 |
| endocardial cell differentiation | biological_process | NOTCH1, NRG1, SMAD4 |
| endocardial cushion cell development | biological_process | JAG1 |
| endocardial cushion development | biological_process | BMP4, ERBB3, NOTCH1 |
| endocardial cushion morphogenesis | biological_process | NOTCH1, TGFB2, HEY1, TWIST1 |
| endocardial cushion to mesenchymal transition involved in heart valve formation | biological_process | EFNA1 |
| endocardium development | biological_process | NOTCH1 |
| endocardium morphogenesis | biological_process | NOTCH1 |
| endochondral bone morphogenesis | biological_process | BMPR1B |
| endochondral ossification | biological_process | BMP4, MMP13, MMP14, BMP6, TEK, DLX5 |
| endocrine pancreas development | biological_process | CLU, AKT1, IL6R, HNF1B, ANXA1, IL6, FOXO1 |
| endocrine signaling | biological_process | KRAS |
| endocytosis | biological_process | NME1, MRC1, SYP, CDC42, RAC1, BCL2L1, DPYSL2 |
| endoderm development | biological_process | NOTCH1, HNF1B, TGFB1, DKK1, SMAD3, SMAD2, SMAD4, NODAL, LAMC1 |
| endoderm formation | biological_process | CTNNB1, DKK1, SMAD2, DUSP2 |
| endodermal cell differentiation | biological_process | INHBA, HMGA2, MMP9, COL4A2, ITGB5, MMP14, FN1, ITGAV, ITGB2, MMP2, GATA6, NODAL |
| endodermal cell fate commitment | biological_process | CTNNB1 |
| endodermal cell fate determination | biological_process | GATA6 |
| endodermal cell fate specification | biological_process | HNF1B, SOX2, POU5F1, NANOG |
| endodermal digestive tract morphogenesis | biological_process | ID2 |
| endoplasmic reticulum calcium ion homeostasis | biological_process | BCL2, BAX |
| endoplasmic reticulum unfolded protein response | biological_process | CCND1, IFNG, NFE2L2, CREB3L1 |
| endosomal lumen acidification | biological_process | CLCN3, FASLG |
| endothelial cell activation | biological_process | CXCL10, FOXP1, SMAD4 |
| endothelial cell chemotaxis | biological_process | VEGFA, HMGB1, NRP1 |
| endothelial cell chemotaxis to fibroblast growth factor | biological_process | CXCL13 |
| endothelial cell development | biological_process | GPX1 |
| endothelial cell differentiation | biological_process | PTN, LAMA5, JAG1, NOTCH4 |
| endothelial cell migration | biological_process | S100P, PIK3CA, NOS3, GREM1, PTP4A3, ITGB2, PTEN, PTK2, CYP1B1, RHOA |
| endothelial cell morphogenesis | biological_process | MET, ID1, COL18A1, NOTCH4, STC1 |
| endothelial cell proliferation | biological_process | HMGB1, HMOX1, MMP14, APOA1, TEK, SCARB1 |
| endothelial cell-cell adhesion | biological_process | CYP1B1 |
| endothelial tip cell fate specification | biological_process | NRP1 |
| endothelial tube lumen extension | biological_process | RHOA |
| endothelial tube morphogenesis | biological_process | CTNNB1 |
| endothelin receptor signaling pathway | biological_process | EDNRA |
| endothelium development | biological_process | GJA1, KDR |
| energy homeostasis | biological_process | STAT3, LEPR, PIK3CA |
| energy reserve metabolic process | biological_process | LEP, LEPR, MTOR, MYC |
| engulfment of apoptotic cell | biological_process | THBS1, RAC1 |
| enteric nervous system development | biological_process | EDNRA |
| entrainment of circadian clock | biological_process | CLOCK, ID2 |
| entrainment of circadian clock by photoperiod | biological_process | TP53, ID2 |
| entry into host cell | biological_process | CCR5, CD4, CXCR4 |
| entry of symbiont into host cell by promotion of host phagocytosis | biological_process | ITGAV |
| enucleate erythrocyte differentiation | biological_process | RB1, ID2 |
| enzyme active site formation via L-cysteine sulfinic acid | biological_process | PARK7 |
| enzyme linked receptor protein signaling pathway | biological_process | AXL, ERBB2, CD4, GAS6 |
| eosinophil chemotaxis | biological_process | CCL5, LGALS3, CCL3, CCL7, CCL11 |
| eosinophil degranulation | biological_process | CCL3 |
| eosinophil fate commitment | biological_process | GATA2 |
| ephrin receptor signaling pathway | biological_process | CRK, SRC, MMP9, EFNA1, FYN, KALRN, MMP2, CDC42, RAC1, PTK2, ACTB, PAK1, RHOA |
| epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification | biological_process | NODAL |
| epidermal cell differentiation | biological_process | HDAC2, HDAC1 |
| epidermal cell division | biological_process | TP63 |
| epidermal growth factor receptor signaling pathway | biological_process | SRC, PIK3R1, SHC1, TDGF1, PIK3CA, EGFR, TGFB1, EGF, NRAS, KRAS, PTK2, ADAM17 |
| epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade | biological_process | RASSF2 |
| epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway | biological_process | ADAM17 |
| epidermis development | biological_process | NOTCH1, STS, NTF4, ALDH3A2, INSR, EGFR, PPARA, TP63, LAMC2 |
| epidermis morphogenesis | biological_process | FGFR2, CDC42 |
| epinephrine metabolic process | biological_process | ATP7A |
| epithelial cell development | biological_process | ESR1, CXCR4, TP63 |
| epithelial cell differentiation | biological_process | VEGFA, PCNA, PPARG, FGFR2, LGALS3, ANXA4, WT1, AKR1C2, NR5A2, TGFB1I1, CTSB, COL4A1, TP63, GATA6, TAGLN, AKR1C1, DLX5, CRHR2 |
| epithelial cell differentiation involved in mammary gland alveolus development | biological_process | HIF1A, ID2 |
| epithelial cell differentiation involved in prostate gland development | biological_process | CTNNB1, PSAP |
| epithelial cell maturation | biological_process | GJA1 |
| epithelial cell morphogenesis | biological_process | CLDN3, RAC1 |
| epithelial cell proliferation | biological_process | KIT, HNF1B |
| epithelial cell proliferation involved in lung morphogenesis | biological_process | BMP4 |
| epithelial cell proliferation involved in mammary gland duct elongation | biological_process | WNT5A, ESR1 |
| epithelial cell proliferation involved in renal tubule morphogenesis | biological_process | LGR5 |
| epithelial cell proliferation involved in salivary gland morphogenesis | biological_process | FGFR2, TNF, IL6 |
| epithelial cell-cell adhesion | biological_process | CTNNA1, ITGB5, CDC42 |
| epithelial fluid transport | biological_process | CSF2, EDN1 |
| epithelial to mesenchymal transition | biological_process | GSK3B, WNT5A, HMGA2, FGFR2, CTNNB1, NOTCH1, HGF, TGFB1, SNAI1, TGFB2, HIF1A, WNT4 |
| epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | NOTCH1, SNAI1, HEY1, SMAD4 |
| epithelial tube branching involved in lung morphogenesis | biological_process | BMP4, CTNNB1, KRAS |
| epithelial-mesenchymal cell signaling | biological_process | BMP4, CDC42 |
| epithelium development | biological_process | BMP4, HNF1B |
| epoxygenase P450 pathway | biological_process | CYP2A6, CYP2B6, CYP2C19, CYP2E1, CYP1A2, CYP1A1, CYP1B1 |
| ER overload response | biological_process | GSK3B, TP53 |
| ER to Golgi vesicle-mediated transport | biological_process | FOLR1, SERPINA1, GAS6, STX5 |
| ERBB signaling pathway | biological_process | MAPK1, NRG1 |
| ERBB2 signaling pathway | biological_process | SRC, PIK3R1, AKT1, SHC1, ERBB3, PIK3CA, HSP90AA1, EGFR, ERBB2, EGF, NRAS, KRAS, NRG1, PTPRR |
| ERK1 and ERK2 cascade | biological_process | MAPK1, PTGER4, OXTR, IGF1, ITGAV, APOA1, LGALS9, EGF, CCL11 |
| error-free translesion synthesis | biological_process | PCNA |
| error-prone translesion synthesis | biological_process | PCNA |
| erythrocyte development | biological_process | BCL6, TMOD3 |
| erythrocyte differentiation | biological_process | GATA3, INHBA, BMP4, KIT, CASP3, INHA |
| erythrocyte homeostasis | biological_process | AXL, HMOX1 |
| erythropoietin-mediated signaling pathway | biological_process | KIT |
| establishment of cell polarity | biological_process | GSK3B, WNT7A, PTK2 |
| establishment of chromatin silencing | biological_process | SIRT1 |
| establishment of chromosome localization | biological_process | BIRC5 |
| establishment of endothelial barrier | biological_process | ICAM1, F2RL1 |
| establishment of epithelial cell apical/basal polarity | biological_process | WNT5A |
| establishment of epithelial cell polarity | biological_process | HES5 |
| establishment of Golgi localization | biological_process | CDC42 |
| establishment of integrated proviral latency | biological_process | HMGA1, XRCC4 |
| establishment of macromolecular complex localization to telomere | biological_process | ATM |
| establishment of mitotic spindle orientation | biological_process | SPRY2 |
| establishment of nucleus localization | biological_process | PTK2 |
| establishment of planar polarity | biological_process | WNT5A, TP63 |
| establishment of protein localization | biological_process | ITGA2, PLK1 |
| establishment of protein localization to Golgi | biological_process | NRAS |
| establishment of protein localization to membrane | biological_process | BRAF |
| establishment of protein localization to mitochondrion | biological_process | AKT1 |
| establishment of protein localization to plasma membrane | biological_process | CDH1, TNFRSF1A, TNF, LAMA5, WNT4 |
| establishment of protein localization to telomere | biological_process | BRCA2, TERT |
| establishment of RNA localization to telomere | biological_process | ATM |
| establishment of Sertoli cell barrier | biological_process | ICAM1 |
| establishment of skin barrier | biological_process | CLDN4, KRT1, TP63 |
| establishment of synaptic specificity at neuromuscular junction | biological_process | F2R |
| establishment of T cell polarity | biological_process | CCL21, CCL19, CCR7 |
| establishment or maintenance of apical/basal cell polarity | biological_process | CDC42 |
| establishment or maintenance of cell polarity | biological_process | GSK3B, CTNNA1, CDC42 |
| establishment or maintenance of transmembrane electrochemical gradient | biological_process | BAX |
| estrogen biosynthetic process | biological_process | CYP19A1, HSD17B1, STAR, HSD17B7 |
| estrogen metabolic process | biological_process | HSD17B1, COMT, IL1B, CYP1B1, SULT1E1 |
| estrous cycle | biological_process | WNT5A, MMP13, CLU, OPRM1, MMP7, PTN, OXTR, ANXA1, ESR2 |
| ethylene metabolic process | biological_process | CYP1A1 |
| evasion or tolerance of host defenses by virus | biological_process | TGFB1, SMAD3 |
| excitatory postsynaptic potential | biological_process | OPRM1, GHRL |
| excitatory synapse assembly | biological_process | WNT5A, WNT7A |
| excretion | biological_process | HMOX1, TACR2, AQP2, AQP5 |
| execution phase of apoptosis | biological_process | AKT1, CASP3 |
| exocrine pancreas development | biological_process | INSR |
| exocytosis | biological_process | CCL5, CCL3, CCR1, PAK1 |
| exogenous drug catabolic process | biological_process | CYP2A6, CYP2B6, CYP2C19, CYP1A2 |
| exosomal secretion | biological_process | COPS5 |
| exploration behavior | biological_process | ITGA3, AGTR2 |
| extracellular matrix assembly | biological_process | TGFB1, GAS6 |
| extracellular matrix constituent secretion | biological_process | CREB3L1 |
| extracellular matrix disassembly | biological_process | CDH1, MMP13, MMP9, SPP1, ENG, MMP7, MMP10, CD44, TIMP2, MMP14, CMA1, MMP11, BSG, MMP12, FN1, A2M, TIMP1, MMP1, MMP2, MMP3, CTSG, ADAM8, TPSAB1, LAMC2, HTRA1, DCN, LAMC1 |
| extracellular matrix organization | biological_process | CDH1, ITGA6, FGF2, ITGA3, FBLN1, BGN, MMP9, KDR, SPP1, COL4A2, ITGA2, ITGB5, LAMA1, SPARC, CD44, PECAM1, VCAN, VCAM1, ITGB6, MMP11, TNC, BSG, COL18A1, FN1, ITGB3, ITGB1, ITGAV, FGA, TNF, PDGFA, TNFRSF11B, CYR61, LAMA5, SERPINE1, THBS1, ITGB2, COL4A1, ICAM1, COL5A2, TGFB2, PTK2, ATP7A, NFKB2, LOXL1, LAMC2, POSTN, SPOCK2, SMOC2, DCN, LAMC1, CRISPLD2 |
| extracellular negative regulation of signal transduction | biological_process | AGTR2, DKK1, ESR2 |
| extraocular skeletal muscle development | biological_process | FOXL2 |
| extrathymic T cell selection | biological_process | IL15 |
| extrinsic apoptotic signaling pathway | biological_process | INHBA, FASLG, TNFRSF1B, IL6R, G0S2, FAS, IL12A, IFNG, TGFB1, TNF, TLR3, IL33, TGFB2, SMAD3, BAX |
| extrinsic apoptotic signaling pathway in absence of ligand | biological_process | GSK3B, BCL2, ERBB3, CASP3, KITLG, FAS, ITGAV, IL1A, BCL2L11, IL1B, IL4, BCL2L1, BAX, MCL1, IL2 |
| extrinsic apoptotic signaling pathway via death domain receptors | biological_process | BCL2, TNFRSF1A, PIK3R1, FASLG, FAS, NGF, TNF, BAX, DAPK1 |
| eye development | biological_process | HMGB1, BMP6, SOX2, BMPR1B, TGFB2 |
| eye morphogenesis | biological_process | COL5A2 |
| eye photoreceptor cell development | biological_process | VEGFA, PRDM1 |
| eye photoreceptor cell differentiation | biological_process | STAT3 |
| eyelid development in camera-type eye | biological_process | INHBA, EGFR, JUN, HDAC2, HDAC1, TWIST1 |
| face development | biological_process | WNT5A, MAPK1, BRAF |
| face morphogenesis | biological_process | TGFB1, CLDN5, DKK1, MMP2, TGFB2, DLX5, CRISPLD2 |
| facial nerve structural organization | biological_process | HOXB2, NRP1, SEMA3A |
| facioacoustic ganglion development | biological_process | NRP1, SEMA3A |
| farnesol catabolic process | biological_process | AKR1C3 |
| fat cell differentiation | biological_process | GSK3B, CCND1, HMGA2, ATF2, IL11, CCR2, INSR, GPX1, FOXO1, PLCB1, RETN |
| fatty acid alpha-oxidation | biological_process | ALDH3A2 |
| fatty acid beta-oxidation | biological_process | LEP, ADIPOQ |
| fatty acid biosynthetic process | biological_process | PTGDS, BRCA1, LIPC, PTGS1, PTGS2, PTGES, ACLY, PTGES2 |
| fatty acid catabolic process | biological_process | LEP |
| fatty acid homeostasis | biological_process | APOE, SIRT1 |
| fatty acid metabolic process | biological_process | PTGDS, ALOX15, HPGD, BRCA1, LIPC, PTGS1, PTGS2, C3, PTGES, PPARA, PTGES2, ADIPOR2, ADIPOR1 |
| fatty acid oxidation | biological_process | PPARG, ADIPOQ, ADIPOR2, ADIPOR1 |
| fatty acid transport | biological_process | PPARA |
| Fc receptor mediated inhibitory signaling pathway | biological_process | LILRB1 |
| Fc receptor mediated stimulatory signaling pathway | biological_process | FCER1G |
| Fc receptor signaling pathway | biological_process | KIT |
| Fc-epsilon receptor signaling pathway | biological_process | MAPK1, PIK3R1, SHC1, NFKB1, PIK3CA, FCER1G, PSMD9, JUN, MAP3K7, MAP2K7, FOS, PSMD10, NRAS, KRAS, RAC1, RELA, PAK1 |
| Fc-gamma receptor signaling pathway | biological_process | FCER1G |
| Fc-gamma receptor signaling pathway involved in phagocytosis | biological_process | CRK, SRC, MAPK1, PIK3R1, PIK3CA, HSP90AA1, FYN, CDC42, RAC1, PTK2, ACTB, PAK1, LIMK1 |
| feeding behavior | biological_process | DRD2, FYN, NTRK2, UCN, NPY |
| female gamete generation | biological_process | FSHR, GDF9, FSHB, ATM |
| female genitalia development | biological_process | SRD5A2, SRD5A1 |
| female genitalia morphogenesis | biological_process | TP63 |
| female gonad development | biological_process | FSHR, BRCA2, FOXL2, NR5A1, ESR2, SMAD4, AMHR2, WNT4 |
| female gonad morphogenesis | biological_process | SMAD4 |
| female meiosis chromosome segregation | biological_process | MLH1, PLK1 |
| female meiotic division | biological_process | HSF1 |
| female pregnancy | biological_process | BCL2, CRHR1, IGFBP2, LEP, HPGD, PTGER4, IGFBP5, ITGA2, CRHBP, STS, IDO1, COMT, OXTR, ADM, PTGER3, IGF1, TGFB1, LGALS9, CLDN4, FOS, FSHB, PRL, IGF2, GC, RLN1, IL4, CRH, PCSK5, UCN, HSD11B2, PAPPA, OVGP1, ADIPOR2 |
| female sex determination | biological_process | WNT4 |
| female somatic sex determination | biological_process | FOXL2 |
| ferrous iron import into cell | biological_process | TF |
| fertilization | biological_process | NR2F2, BCL2L1, BAX, NECTIN3 |
| fever generation | biological_process | IL1A, IL1B |
| fibrinolysis | biological_process | FGA, PLAT, ANXA2, SERPINE1, PLAU, KRT1, SERPINB2, PLAUR, CPB2 |
| fibroblast activation | biological_process | IL17A |
| fibroblast apoptotic process | biological_process | MYC |
| fibroblast growth factor receptor signaling pathway | biological_process | FGFR1, FGF2, MAPK1, FGFR2, TIA1, FGF1 |
| fibroblast growth factor receptor signaling pathway involved in hemopoiesis | biological_process | FGFR2 |
| fibroblast growth factor receptor signaling pathway involved in mammary gland specification | biological_process | FGFR2 |
| fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow | biological_process | FGFR2 |
| fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development | biological_process | FGFR1, FGFR2 |
| fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow | biological_process | FGFR2 |
| fibroblast proliferation | biological_process | EDNRA |
| filopodium assembly | biological_process | ITGA6, CDC42 |
| flagellated sperm motility | biological_process | SLC26A8 |
| flavonoid metabolic process | biological_process | CYP1A1 |
| floor plate morphogenesis | biological_process | NODAL |
| focal adhesion assembly | biological_process | BCL2, ITGA2, LAMA5 |
| folic acid metabolic process | biological_process | FOLR1, MTHFR |
| folic acid transport | biological_process | FOLR1 |
| folic acid-containing compound metabolic process | biological_process | FOLH1 |
| follicle-stimulating hormone signaling pathway | biological_process | FSHR, FSHB |
| follicular dendritic cell differentiation | biological_process | NFKB2 |
| forebrain anterior/posterior pattern specification | biological_process | WNT1 |
| forebrain astrocyte development | biological_process | KRAS |
| forebrain cell migration | biological_process | AXL, TYRO3, EMX2 |
| forebrain development | biological_process | SRC, NR2F2, BMP4, CTNNB1, NOTCH1, DRD2, SSTR1, SOX2, CCR2, FYN, ARID1A, DKK1, EMX2 |
| forebrain morphogenesis | biological_process | PTEN |
| forebrain neuron differentiation | biological_process | CSF1R |
| forebrain radial glial cell differentiation | biological_process | HES5 |
| foregut morphogenesis | biological_process | NOTCH1 |
| formaldehyde metabolic process | biological_process | ALDH3A2 |
| formation of anatomical boundary | biological_process | SMAD4, NODAL |
| formation of radial glial scaffolds | biological_process | ITGB1 |
| formation of translation preinitiation complex | biological_process | EIF3E |
| frontal suture morphogenesis | biological_process | TGFB1 |
| fructose biosynthetic process | biological_process | AKR1B1 |
| fungiform papilla formation | biological_process | CTNNB1, HDAC2, HDAC1 |
| fusion of virus membrane with host plasma membrane | biological_process | CCR5, CD4, GAS6, CXCR4 |
| G-protein coupled acetylcholine receptor signaling pathway | biological_process | PLCB1 |
| G-protein coupled receptor internalization | biological_process | DRD2, ADM |
| G-protein coupled receptor signaling pathway | biological_process | FSHR, CRHR1, F2R, PPARG, CCL5, IGF2R, CXCL8, OPRM1, AKT1, PTGER4, CCL3, DRD2, FPR1, CCR1, CCR5, CXCR3, AGTR1, AGTR2, EDNRA, CXCL1, CXCR1, CXCR2, CCL2, CXCL2, TACR2, TACR1, LHCGR, OXTR, SSTR1, SSTR5, CCR2, AKR1C3, CXCL5, PTGFR, PTGER3, PTGER2, CXCL12, CCR9, AKR1C2, INSR, LGR5, APOA1, APOE, CXCL10, C3, CCL25, CXCR6, CCL21, CCL22, DEFB4A, CCL16, CXCL13, C5, EDN1, RAC1, CXCR4, F2RL1, GHRL, CCL19, GPER1, UCN, CCL7, CX3CL1, DEFB1, IL2, SST, PLCB3, KISS1R, CXCL6, CRHR2, SFRP4, CCL17, HRH4, LPAR3, CCR7, CCL11, CCR8, ADIPOR2, ADIPOR1, RXFP1 |
| G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger | biological_process | AGTR2 |
| G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | biological_process | OPRM1, CCR1, CCL2, LHCGR, SSTR1, SSTR5, ANXA1, LPAR3, NPY |
| G1 to G0 transition | biological_process | EZH2 |
| G1/S transition of mitotic cell cycle | biological_process | INHBA, CCND1, PCNA, CDKN1B, CDKN1A, CDKN2A, ITGB1, LATS1, RB1, EIF4EBP1, PIM2 |
| G2 DNA damage checkpoint | biological_process | BRCA1, PLK1 |
| G2/M transition of mitotic cell cycle | biological_process | CCNB1, CDKN1A, CHEK2, AURKA, HSP90AA1, BIRC5, LATS1, ABCB1, PLK1, PLCB1 |
| GABAergic neuron differentiation | biological_process | INHBA, GATA2 |
| galactose catabolic process | biological_process | PGM1, GALT |
| galactose metabolic process | biological_process | GALT |
| gamete generation | biological_process | WNT4 |
| gamma-delta T cell activation | biological_process | MICA, MICB |
| ganglion mother cell fate determination | biological_process | NTF4 |
| gap junction assembly | biological_process | GJA1, CTNNA1 |
| gastric acid secretion | biological_process | GHRL |
| gastric emptying | biological_process | UCN |
| gastric motility | biological_process | CRHR2 |
| gastrulation | biological_process | CFC1B, SMAD3, SMAD2, SMAD4, NODAL |
| gastrulation with mouth forming second | biological_process | CTNNB1, SMAD4, NODAL |
| gene expression | biological_process | FAS |
| gene silencing | biological_process | DNMT1 |
| gene silencing by RNA | biological_process | DICER1, HIST2H3A |
| generation of neurons | biological_process | FGFR1, TGFB2 |
| generation of ovulation cycle rhythm | biological_process | KISS1 |
| generation of precursor metabolites and energy | biological_process | ATP5B, ADIPOQ |
| genitalia development | biological_process | WNT5A, HNF1B |
| genitalia morphogenesis | biological_process | CTNNB1 |
| germ cell development | biological_process | MSH2, BMP4, AKT1, WT1, MTOR, ANGPT2, PRDM1, BCL2L1, BAX |
| germ cell migration | biological_process | KIT, ITGB1, TGFB1 |
| germinal center B cell differentiation | biological_process | ADA |
| germinal center formation | biological_process | BCL6, CXCL13, NFKB2, ADAM17 |
| gland morphogenesis | biological_process | BCL2, FGFR2 |
| glial cell apoptotic process | biological_process | CASP3, RB1, BAX |
| glial cell differentiation | biological_process | NOTCH1, NRG1, PAX2, MMP24 |
| glial cell fate commitment | biological_process | SOX2, NRG1, HES5 |
| glial cell fate determination | biological_process | CTNNB1 |
| glial cell migration | biological_process | CCL2, VCAN, FN1, TGFB2 |
| gliogenesis | biological_process | ANXA1, ADAM22 |
| glomerular basement membrane development | biological_process | WT1 |
| glomerular capillary formation | biological_process | BMP4 |
| glomerular endothelium development | biological_process | PECAM1 |
| glomerular filtration | biological_process | EDNRA |
| glomerular mesangial cell development | biological_process | NOTCH1 |
| glomerular mesangial cell proliferation | biological_process | EGR1 |
| glomerular parietal epithelial cell differentiation | biological_process | PROM1 |
| glomerular visceral epithelial cell development | biological_process | BMP4, JAG1 |
| glomerular visceral epithelial cell differentiation | biological_process | WT1, PROM1 |
| glomerulus development | biological_process | BCL2, WT1 |
| glomerulus vasculature development | biological_process | ANGPT2, ANGPT1 |
| glucagon secretion | biological_process | IL6 |
| glucocorticoid biosynthetic process | biological_process | HSD3B2, CYP17A1, CYP11A1, CRH, HSD11B2 |
| glucocorticoid catabolic process | biological_process | YWHAH |
| glucocorticoid mediated signaling pathway | biological_process | SGK1, NR3C1 |
| glucocorticoid metabolic process | biological_process | STAR, SERPINA6, APOA1, HSD11B2 |
| glucocorticoid receptor signaling pathway | biological_process | ARID1A, NR3C1, YWHAH |
| gluconeogenesis | biological_process | PGM1, ENO2, ENO1 |
| glucose homeostasis | biological_process | STAT3, PPARG, LEP, AKT1, IGFBP5, USF1, LEPR, SSTR5, INSR, IL6, HIF1A, FOXO1, ADIPOQ, ADIPOR2, ADIPOR1 |
| glucose metabolic process | biological_process | PGM1, LEP, AKT1, IGFBP5, USF1, PIK3CA, TNF, IGF2, ADIPOQ, GHRL, IRS2 |
| glucose transport | biological_process | AKT1, BRAF, EDNRA, EDN1, NRG1 |
| glutamate metabolic process | biological_process | GCLC |
| glutamate receptor signaling pathway | biological_process | SSTR1, PLCB1 |
| glutamate secretion | biological_process | NTRK2 |
| glutathione biosynthetic process | biological_process | GCLC |
| glutathione derivative biosynthetic process | biological_process | GSTP1, GSTM1, GSTT1, GSTZ1 |
| glutathione metabolic process | biological_process | GCLC, GSTP1, GSTM1, GSTT1, GSTZ1, SOD1, GPX1 |
| glycerol biosynthetic process | biological_process | LEP |
| glycerol ether metabolic process | biological_process | TXN |
| glycerol transport | biological_process | AQP2, AQP8, AQP5 |
| glycerophospholipid catabolic process | biological_process | LIPC |
| glycerophospholipid metabolic process | biological_process | PEMT |
| glycogen biosynthetic process | biological_process | PGM1, AKT1 |
| glycogen catabolic process | biological_process | PGM1 |
| glycogen cell differentiation involved in embryonic placenta development | biological_process | AKT1 |
| glycogen metabolic process | biological_process | GSK3B, AKT1, IL6ST |
| glycolate biosynthetic process | biological_process | PARK7 |
| glycolate metabolic process | biological_process | IGF1 |
| glycolipid biosynthetic process | biological_process | GBGT1 |
| glycolytic process | biological_process | PGM1, ENO2, ENO1 |
| glycoprotein metabolic process | biological_process | IL1B, AGER |
| glycosaminoglycan biosynthetic process | biological_process | SDC4, SDC1, XYLT2 |
| glycosaminoglycan catabolic process | biological_process | SDC4, SDC1, HPSE, NAGLU |
| glycosaminoglycan metabolic process | biological_process | BGN, SDC4, VCAN, SDC1, DCN |
| glycosphingolipid metabolic process | biological_process | KIT, STS, PSAP, BAX, ARSH, SMPD3 |
| glyoxal catabolic process | biological_process | PARK7 |
| Golgi disassembly | biological_process | STX5 |
| Golgi organization | biological_process | CDC42 |
| Golgi to plasma membrane transport | biological_process | CCDC22 |
| gonad development | biological_process | FSHR, WT1, AMH |
| gonadal mesoderm development | biological_process | AMH |
| gonadotrophin-releasing hormone neuronal migration to the hypothalamus | biological_process | NRP1, SEMA3A |
| granulocyte chemotaxis | biological_process | CCL3, ANXA1 |
| granulocyte macrophage colony-stimulating factor biosynthetic process | biological_process | IL18 |
| granulosa cell differentiation | biological_process | CAPN5, FOXL2 |
| grooming behavior | biological_process | DRD2 |
| growth | biological_process | BCL2, INHBA, VEGFA, BMP4, CNTF, BMP6, MTOR, TGFB1, MSTN, TGFB2, BCL2L1 |
| growth factor dependent regulation of skeletal muscle satellite cell proliferation | biological_process | FGF2 |
| growth hormone receptor signaling pathway | biological_process | STAT3, PIK3R1, PTK2 |
| growth hormone secretion | biological_process | GHRH, GHRL |
| growth involved in heart morphogenesis | biological_process | NOTCH1 |
| growth plate cartilage axis specification | biological_process | STC1 |
| growth plate cartilage development | biological_process | MMP13 |
| GTP biosynthetic process | biological_process | NME1 |
| hair cell differentiation | biological_process | CTNNB1 |
| hair cycle | biological_process | PTGS2 |
| hair cycle process | biological_process | CTNNB1, CDH3 |
| hair follicle development | biological_process | INHBA, EGFR, LGR5, PDGFA, LAMA5, DKK1, TGFB2, RELA, TP63 |
| hair follicle morphogenesis | biological_process | BCL2, FGFR2, CTNNB1, NOTCH1, IGFBP5, SNAI1, CDC42, TGFB2, ATP7A, TP63 |
| hair follicle placode formation | biological_process | CTNNB1, CDC42, HDAC2, HDAC1 |
| halogenated hydrocarbon metabolic process | biological_process | CYP2E1 |
| head development | biological_process | EDNRA, DLX5, IL11RA |
| head morphogenesis | biological_process | BRAF, DKK1 |
| heart contraction | biological_process | ACE, SOD1, GPX1, CDC42 |
| heart development | biological_process | GATA3, BMP4, PCNA, ITGA3, PPARG, MMP13, MAPK1, GJA1, SHC1, CTNNB1, ERBB3, NOTCH1, ID1, CASP3, ENG, EDNRA, GATA2, SPARC, TDGF1, WT1, PTN, OXTR, ADM, ERBB2, NRP1, EDN1, PTEN, TGFB2, NRG1, TEK, SMAD2, PPARA, ID2, ATM, PCSK5, NODAL, SEMA3C, GATA5, ADIPOR2 |
| heart looping | biological_process | WNT5A, FOLR1, GJA1, NOTCH1, ENG, SMAD3, HIF1A, IHH, NODAL |
| heart morphogenesis | biological_process | VEGFA, MTOR, INSR, TGFB2, PTK2 |
| heart trabecula formation | biological_process | TEK, HEY1 |
| heart trabecula morphogenesis | biological_process | NOTCH1 |
| heart valve development | biological_process | PRDM1 |
| heart valve morphogenesis | biological_process | MTOR, TGFB2 |
| heat acclimation | biological_process | IL1R1 |
| helper T cell enhancement of adaptive immune response | biological_process | CD4 |
| helper T cell extravasation | biological_process | CCL2 |
| hematopoietic progenitor cell differentiation | biological_process | INHBA, BMP4, FST, TGFB1, FSTL3, SMPD3 |
| hematopoietic stem cell differentiation | biological_process | ACE |
| hematopoietic stem cell homeostasis | biological_process | TET2 |
| hematopoietic stem cell migration | biological_process | KIT |
| hematopoietic stem cell migration to bone marrow | biological_process | GAS6 |
| hematopoietic stem cell proliferation | biological_process | WNT5A, WNT1 |
| heme catabolic process | biological_process | HMOX1, HMOX2 |
| heme metabolic process | biological_process | HMOX1, HPX |
| heme oxidation | biological_process | HMOX1, HMOX2 |
| heme transport | biological_process | HPX, ABCG2 |
| hemidesmosome assembly | biological_process | ITGA6, LAMC2, LAMC1 |
| hemoglobin biosynthetic process | biological_process | INHBA, INHA, HIF1A |
| hemoglobin metabolic process | biological_process | HPX, CAT, TET2 |
| hemopoiesis | biological_process | BCL2, IL10, KIT, CTNNB1, CSF1, BRCA2, GATA2, FLT3, MEIS1, CSF1R, RUNX3, TGFB2, JAG1, ANGPT1, NOTCH4, TET2 |
| hemostasis | biological_process | F2R, F3, ANXA5, FGA, SERPINA1, PLAU, CPB2 |
| heparan sulfate proteoglycan biosynthetic process | biological_process | LIPC, XYLT2 |
| heparan sulfate proteoglycan catabolic process | biological_process | HPSE |
| heparin biosynthetic process | biological_process | XYLT2, ANGPT1 |
| hepatic immune response | biological_process | IL6R, IL6 |
| hepatoblast differentiation | biological_process | HNF1B |
| hepatocyte apoptotic process | biological_process | FAS, RB1, BCL2L1, DNMT3A |
| hepatocyte differentiation | biological_process | ITGA2, HNF1B, ANXA1, WNT1, CYP1A1 |
| hepatocyte growth factor receptor signaling pathway | biological_process | MET, HGF, NRP1, MST1R, MST1 |
| hepatocyte proliferation | biological_process | MKI67 |
| hepoxilin biosynthetic process | biological_process | ALOX15 |
| heterochromatin assembly | biological_process | HMGA2 |
| heterochromatin maintenance | biological_process | MTHFR |
| heterocycle metabolic process | biological_process | CYP2C19, CYP2E1, CYP1A2, CYP1A1 |
| heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | biological_process | VCAM1, SELP, SELE, ICAM1, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
| heterotypic cell-cell adhesion | biological_process | ITGB3, ITGB1, ITGAV, ITGB2 |
| high-density lipoprotein particle assembly | biological_process | APOA1, APOA2, APOE |
| high-density lipoprotein particle clearance | biological_process | APOA1, APOA2, APOE, SCARB1 |
| high-density lipoprotein particle remodeling | biological_process | CETP, LIPC, APOA1, APOA2, APOE, SCARB1 |
| hindbrain development | biological_process | CTNNB1, HNF1B, PTN |
| hindgut morphogenesis | biological_process | WNT5A |
| hindlimb morphogenesis | biological_process | TWIST1 |
| hippo signaling | biological_process | YAP1, CASP3, LATS1 |
| hippocampus development | biological_process | GSK3B, NME1, CASP3, MDK, SRD5A2, CYP17A1, EZH2, SRD5A1 |
| histamine secretion | biological_process | EDNRA, ADA, EDN1 |
| histone acetylation | biological_process | ATF2, CLOCK, KAT2B |
| histone deacetylation | biological_process | HDAC2, HDAC1, SIRT1 |
| histone H2A-S139 phosphorylation | biological_process | HMGA2 |
| histone H3 acetylation | biological_process | BRCA2, MAP3K7, KAT2B |
| histone H3 deacetylation | biological_process | HDAC2, HDAC1, SIRT1 |
| histone H3-K27 methylation | biological_process | EZH2, EHMT2 |
| histone H3-K27 trimethylation | biological_process | CHD5 |
| histone H3-K4 trimethylation | biological_process | TET3, TET2 |
| histone H3-K9 acetylation | biological_process | KAT2B |
| histone H3-K9 deacetylation | biological_process | SIRT1 |
| histone H3-K9 dimethylation | biological_process | SUV39H1, SUV39H2 |
| histone H3-K9 methylation | biological_process | EHMT2 |
| histone H3-K9 modification | biological_process | SIRT1 |
| histone H3-K9 trimethylation | biological_process | SUV39H1, SUV39H2 |
| histone H3-S10 phosphorylation involved in chromosome condensation | biological_process | CCNB1 |
| histone H3-T6 phosphorylation | biological_process | PRKCB |
| histone H4 acetylation | biological_process | BRCA2, CHD5 |
| histone H4 deacetylation | biological_process | HDAC2, HDAC1 |
| histone lysine methylation | biological_process | SUV39H1, EHMT2, SUV39H2 |
| histone methylation | biological_process | EZH2, EHMT2 |
| histone mRNA catabolic process | biological_process | ATM |
| histone phosphorylation | biological_process | ATM |
| histone-serine phosphorylation | biological_process | AURKA |
| homeostasis of number of cells | biological_process | GATA3, RASSF2, BAX, CCR7, TET2 |
| homeostasis of number of cells within a tissue | biological_process | BCL2, F2R, CSF1, GATA2, KRAS, RAC1, BAX, IL20RB |
| homeostatic process | biological_process | ANG, NR5A2 |
| homocysteine metabolic process | biological_process | MTHFR |
| homologous chromosome orientation involved in meiotic metaphase I plate congression | biological_process | BRCA2 |
| homologous chromosome segregation | biological_process | MLH1, PLK1 |
| homophilic cell adhesion via plasma membrane adhesion molecules | biological_process | CDH1, CDH3, ITGB1, PCDH17, NECTIN1, NECTIN3, CADM1, TRO, NECTIN4, CADM2 |
| hormone biosynthetic process | biological_process | CYP17A1 |
| hormone catabolic process | biological_process | ACE |
| hormone metabolic process | biological_process | LEP, CRHBP, NR5A1, WNT4 |
| hormone secretion | biological_process | ADM |
| hormone-mediated apoptotic signaling pathway | biological_process | CRH, SST |
| hormone-mediated signaling pathway | biological_process | FSHR, CRHBP, LHCGR, LATS1, NR5A2, NR5A1, GHRL, CRHR2, ADIPOR2, ADIPOR1 |
| humoral immune response | biological_process | BCL2, GATA3, NOTCH1, CCL2, IFNG, LTF, TNF, TNFRSF21, LTA, IL6, CD83 |
| humoral immune response mediated by circulating immunoglobulin | biological_process | HLA-DRB1 |
| hyaluronan biosynthetic process | biological_process | IL1B |
| hyaluronan catabolic process | biological_process | FGF2, CD44, TGFB1 |
| hyaluronan metabolic process | biological_process | AKT1, HGF, IL15, MKI67 |
| hydrogen ion transmembrane transport | biological_process | MT-CO2 |
| hydrogen peroxide biosynthetic process | biological_process | SOD1, CYP1A2, CYP1A1 |
| hydrogen peroxide catabolic process | biological_process | PRDX6, GPX3, LPO, GPX1, CAT, MPO |
| hydrogen peroxide metabolic process | biological_process | PARK7 |
| hypermethylation of CpG island | biological_process | GSK3B, DNMT3A |
| hyperosmotic response | biological_process | TLR3, RAC1, SST |
| hypochlorous acid biosynthetic process | biological_process | MPO |
| hypomethylation of CpG island | biological_process | PIK3CA |
| hypophysis morphogenesis | biological_process | WNT5A |
| hypothalamus development | biological_process | SRD5A2, CRH, BAX, ESR2, CRHR2, SRD5A1 |
| hypotonic response | biological_process | ITGA2 |
| hypoxanthine biosynthetic process | biological_process | ADA |
| hypoxanthine salvage | biological_process | ADA |
| hypoxia-inducible factor-1alpha signaling pathway | biological_process | HIF1A |
| I-kappaB kinase/NF-kappaB signaling | biological_process | TNFRSF1A, NFKB1, MAP3K7, TNF, TLR4, TLR3, NFKB2 |
| I-kappaB phosphorylation | biological_process | MAP3K7, TLR2, TLR4, TLR3, TLR9 |
| icosanoid biosynthetic process | biological_process | PLA2G4A |
| icosanoid metabolic process | biological_process | PLA2G4A |
| immature B cell differentiation | biological_process | KIT |
| immature T cell proliferation in thymus | biological_process | WNT4 |
| immune response | biological_process | CRHR1, CD40LG, TNFRSF1A, CCL5, CD36, IL10, CXCL8, PTGER4, CCL3, TNFSF10, NOTCH1, FASLG, CCR1, CCR5, TNFRSF1B, CD40, HLA-DRB1, CXCL1, IL1R1, HLA-C, AZGP1, FAS, CCL2, HLA-E, IL15, LIF, IL9, CTLA4, HLA-G, IL1RN, IL1R2, CXCL2, BMP6, CMA1, KIR2DL1, KIR2DL3, IL12A, HLA-A, IL13, ZEB1, CCR2, CXCL5, KIR3DL1, CXCL12, CCR9, IFNG, IGF1R, IL1A, TNF, CXCL10, C3, TLR2, TLR4, CD4, CCL25, TNFRSF11B, CCL21, CCL22, SLPI, DEFB4A, CCL16, THBS1, CXCL13, TNFRSF21, IL1B, CXCL14, PNP, LTA, IL2RA, HLA-B, HLA-DQA1, CSF2, CD74, HLA-DPB1, IL4, IL5, IL6, CTSG, C1QBP, SMAD3, IL18, CCL19, NECTIN1, TNFSF13B, IL1RL1, IL24, MICA, IL23A, CCL7, CX3CL1, DEFB1, IL2, CXCL6, HAMP, IL10RB, IL16, KIR2DS5, IL17A, MICB, IL22, CCL17, SEMA3C, ULBP2, IL1RAP, IL37, CCL27, HLA-DRA, CD1A, CCR7, CCL11, CCR8, KIR3DS1 |
| immune response to tumor cell | biological_process | MICA |
| immune response-activating cell surface receptor signaling pathway | biological_process | MICB |
| immune response-inhibiting cell surface receptor signaling pathway | biological_process | HLA-G, LILRB1 |
| immune response-inhibiting signal transduction | biological_process | IL20RB |
| immune response-regulating cell surface receptor signaling pathway | biological_process | CD40 |
| immune system development | biological_process | BCL2, SMAD3 |
| immune system process | biological_process | SRC, GATA3, BCL6, HMGB1, LGALS3, CLU, MIF, MBL2, CSF1, CD40, AXL, HLA-DRB1, C4A, HLA-C, CD79A, HLA-E, IDO1, CTLA4, HLA-G, HLA-A, ANXA1, FGA, PRKCB, LTF, C3, LGALS9, TLR2, TLR4, CD4, FYN, SLPI, TLR3, TNFRSF21, HP, C5, IL2RA, HLA-B, HLA-DQA1, C4BPA, CD74, HLA-DPB1, CSF1R, C1QBP, F2RL1, TLR9, NOD2, TNFSF13B, MST1R, NOD1, PTPN22, GPER1, CADM1, MICA, IL23A, IL2, MICB, IL27, ISG20, IL1RAP, HLA-DRA, CD1A, KLRK1, LILRB1 |
| immunoglobulin mediated immune response | biological_process | FCER1G, CD74 |
| immunoglobulin production | biological_process | FAS |
| immunoglobulin production involved in immunoglobulin mediated immune response | biological_process | HLA-DRB1 |
| immunoglobulin secretion | biological_process | CD40LG |
| immunological synapse formation | biological_process | CCL21, CCL19 |
| in utero embryonic development | biological_process | MSH2, FGFR1, GATA3, VEGFA, NR2F2, FGFR2, GJA1, CTNNB1, CCNB1, NOTCH1, EDNRA, NOS3, HSD17B2, ITGB1, ENO1, BCL2L11, PRDM1, ADA, C5, EDN1, SMAD3, BCL2L1, HSF1, SMAD2, ATP7A, RARRES2, SMAD4, TWIST1, GATA6, PTPRR, ANGPT1, NODAL |
| inactivation of MAPK activity | biological_process | DUSP2 |
| inactivation of MAPKK activity | biological_process | IGF1R |
| induction by virus of host cell-cell fusion | biological_process | CD4 |
| induction of bacterial agglutination | biological_process | FGA |
| induction of positive chemotaxis | biological_process | VEGFA, CXCL8, VEGFC, CXCL12, FIGF, IL16 |
| inflammatory cell apoptotic process | biological_process | FASLG, FAS, IFNG |
| inflammatory response | biological_process | BCL6, CD40LG, F2R, TNFRSF1A, CCL5, HMGB1, ALOX15, CHI3L1, IL10, KIT, CXCL8, MIF, AKT1, CCL3, NFKB1, SPP1, CSF1, CCR1, CCR5, CXCR3, TNFRSF1B, CD40, AXL, AGTR2, CRHBP, CXCL1, C4A, CXCR1, CXCR2, FAS, CCL2, IL15, IDO1, IL9, SELP, SELE, ITGB6, SDC1, CXCL2, TACR1, BMP6, IGFBP4, PTGS1, PTX3, IL13, PTGS2, CCR2, CXCL5, TGFB1, ANXA1, IL1A, TNF, CXCL10, C3, LGALS9, TLR2, TLR4, CCL25, BMPR1B, TNFRSF11B, CXCR6, CCL21, CRP, CCL22, FOS, TLR3, CCL16, THBS1, CXCL13, TNFRSF21, IL1B, ITGB2, C5, IL2RA, IL5, IL6, CRH, CSF1R, RAC1, RELA, PARK7, NTRK2, CXCR4, F2RL1, TLR9, NFE2L2, AIF1, IL18, CCL19, NFKB2, RARRES2, NOD1, AGER, GPER1, ADAM8, IL24, UCN, IL23A, CCL7, CXCL6, IL10RB, IL17A, IL22, IL27, CCL17, IL17F, HRH4, IL1RAP, IL37, CHST2, CCR7, CCL11 |
| inflammatory response to antigenic stimulus | biological_process | HMGB1, NOTCH1, HLA-DRB1, CCR2, IL2RA, IL20RB |
| inhibition of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | BIRC5 |
| inhibition of neuroepithelial cell differentiation | biological_process | NODAL |
| inhibitory postsynaptic potential | biological_process | CX3CL1 |
| inhibitory synapse assembly | biological_process | WNT5A |
| innate immune response | biological_process | SRC, GATA3, PPARG, HMGB1, LGALS3, CLU, MIF, NFKB1, MBL2, CSF1, AXL, JAK1, TYK2, C4A, SAA1, HLA-E, PTX3, FCER1G, KIR2DS4, ANG, ANXA1, FGA, C3, TLR2, TLR4, FYN, SLPI, DEFB4A, TLR3, C5, APCS, C4BPA, CSF1R, C1QBP, PTK2, F2RL1, TLR9, NOD2, NFKB2, MST1R, NOD1, AGER, GPER1, KLRD1, IL23A, DEFB1, KIR2DS5, IL27, ISG20, IL1RAP, NPY, KLRK1, KIR3DS1 |
| innate immune response in mucosa | biological_process | NOS2, LTF, IL4, DEFB1 |
| inner cell mass cell differentiation | biological_process | HNF1B, TET1 |
| inner cell mass cell fate commitment | biological_process | LATS1 |
| inner cell mass cell proliferation | biological_process | BRCA2 |
| inner cell mass cellular morphogenesis | biological_process | LATS1 |
| inner ear development | biological_process | CDKN1B, SPARC, SOX2, TGFB1, LGR5, PDGFA, CXCL14, JAG1, MAF |
| inner ear morphogenesis | biological_process | FGFR1, GATA3, WNT5A, FGFR2, GATA2, SPRY2, WNT1, PAX2, DLX5 |
| inner ear receptor cell development | biological_process | NAGLU |
| inner ear receptor cell differentiation | biological_process | BMP4 |
| inner ear receptor stereocilium organization | biological_process | SDC4, HES5 |
| inner medullary collecting duct development | biological_process | AKR1B1 |
| inner mitochondrial membrane organization | biological_process | BAX |
| innervation | biological_process | NTF4 |
| inosine biosynthetic process | biological_process | ADA |
| inosine catabolic process | biological_process | PNP |
| inositol phosphate biosynthetic process | biological_process | FGF2 |
| inositol phosphate dephosphorylation | biological_process | PTEN |
| inositol phosphate metabolic process | biological_process | PLCD1, PTEN, PLCB1, PLCB3, PLCD3 |
| inositol phosphate-mediated signaling | biological_process | EDN1 |
| insecticide metabolic process | biological_process | STAR, CYP1A1 |
| insulin receptor signaling pathway | biological_process | PIK3R1, AKT1, SHC1, IGFBP1, INSR, IGF1R, IGF2, FOXO1, EIF4EBP1, IRS2 |
| insulin receptor signaling pathway via phosphatidylinositol 3-kinase | biological_process | PIK3CA, IGF2 |
| insulin secretion | biological_process | LEP, IL1RN, HNF1B, ANXA1, SMAD2 |
| insulin-like growth factor receptor signaling pathway | biological_process | IGF2R, PIK3R1, AKT1, IGF1, IGF1R, PLCB1 |
| integrin activation | biological_process | FN1, CX3CL1 |
| integrin-mediated signaling pathway | biological_process | SRC, ITGA6, ITGA3, FBLN1, ITGA2, ITGB5, ITGB6, FCER1G, ITGB3, ITGB1, ITGAV, APOA1, LAMA5, ITGB2, PTK2 |
| intein-mediated protein splicing | biological_process | IHH |
| interaction with symbiont | biological_process | GPX1 |
| interferon-gamma biosynthetic process | biological_process | IL12B, IL18 |
| interferon-gamma production | biological_process | TLR4, LILRB1 |
| interferon-gamma secretion | biological_process | GATA3, F2RL1, LILRB1 |
| interferon-gamma-mediated signaling pathway | biological_process | HLA-DRB1, JAK1, HLA-C, CD44, NCAM1, HLA-E, VCAM1, HLA-G, HLA-A, IFNG, HLA-B, HLA-DQA1, ICAM1, HLA-DPB1, HLA-DRA |
| interleukin-1 alpha secretion | biological_process | S100A13 |
| interleukin-1 beta biosynthetic process | biological_process | CMA1 |
| interleukin-1 beta production | biological_process | CASP1, IL1B |
| interleukin-1 beta secretion | biological_process | CD36, TLR4, F2RL1 |
| interleukin-1-mediated signaling pathway | biological_process | EGR1, IL1R1, PLCB1 |
| interleukin-10 production | biological_process | TLR2 |
| interleukin-10 secretion | biological_process | F2RL1 |
| interleukin-11-mediated signaling pathway | biological_process | IL6ST |
| interleukin-12 secretion | biological_process | CCL19, CCR7 |
| interleukin-12-mediated signaling pathway | biological_process | PLCB1 |
| interleukin-13 biosynthetic process | biological_process | IL18 |
| interleukin-15-mediated signaling pathway | biological_process | PLCB1 |
| interleukin-2 biosynthetic process | biological_process | IL18 |
| interleukin-2 production | biological_process | STOML2 |
| interleukin-2 secretion | biological_process | PNP |
| interleukin-2-mediated signaling pathway | biological_process | JAK1, IL2RB, IL2RA |
| interleukin-21 secretion | biological_process | FOXP1 |
| interleukin-27-mediated signaling pathway | biological_process | IL6ST |
| interleukin-3-mediated signaling pathway | biological_process | CSF2RB |
| interleukin-33-mediated signaling pathway | biological_process | IL1RL1 |
| interleukin-4 secretion | biological_process | GATA3, NOTCH1 |
| interleukin-4-mediated signaling pathway | biological_process | STAT6 |
| interleukin-5-mediated signaling pathway | biological_process | CSF2RB |
| interleukin-6 secretion | biological_process | NOS2, LEP |
| interleukin-6-mediated signaling pathway | biological_process | STAT3, IL6R, IL6ST, IL6, SMAD4 |
| interleukin-8 biosynthetic process | biological_process | NOD1 |
| interleukin-8 secretion | biological_process | NOS2, CHI3L1, LEP |
| interleukin-8-mediated signaling pathway | biological_process | CXCR1, CXCR2 |
| intermediate filament organization | biological_process | VIM |
| intermediate filament-based process | biological_process | VIM |
| intermediate mesodermal cell differentiation | biological_process | BMP4 |
| intermediate-density lipoprotein particle remodeling | biological_process | LIPC |
| internal peptidyl-lysine acetylation | biological_process | KAT2B |
| intestinal absorption | biological_process | CD36, LEP, VDR, SCARB1 |
| intestinal cholesterol absorption | biological_process | CD36, AKR1C1 |
| intestinal epithelial cell development | biological_process | PRDM1 |
| intestinal epithelial cell differentiation | biological_process | GATA6, GATA5 |
| intestinal epithelial cell maturation | biological_process | CDKN1A, HIF1A |
| intestinal epithelial structure maintenance | biological_process | TLR4 |
| intestine smooth muscle contraction | biological_process | TACR2, PTGER3 |
| intra-S DNA damage checkpoint | biological_process | MSH2, ATF2 |
| intracellular cholesterol transport | biological_process | STAR |
| intracellular estrogen receptor signaling pathway | biological_process | SRC, ESR1, ARID1A, ESR2 |
| intracellular pH elevation | biological_process | CFTR |
| intracellular protein transport | biological_process | PDCD6, CD74, YWHAH, STX5, CSE1L, IPO13 |
| intracellular receptor signaling pathway | biological_process | STAT3, NR2F2, AR, AHR, FLT1, ARNT, PTGER3, NR5A2, NR5A1, PPARA |
| intracellular signal transduction | biological_process | GSK3B, SRC, MAPK1, KIT, LEP, CXCL8, AKT1, SHC1, DRD2, CASP3, PLCD1, BRAF, AGTR2, JAK1, IGFBP5, TYK2, CXCL1, HMOX1, STMN1, PRKCB, HSPB1, FYN, SGK1, SMAD7, SOCS3, KALRN, EDN1, RAC1, NRG1, PLCB1, TEK, SMAD2, NOD2, NOD1, SMAD4, DAPK1, PLCB3, KSR1, PLCD3 |
| intracellular steroid hormone receptor signaling pathway | biological_process | ESR1, ESR2, GPER1 |
| intracellular transport | biological_process | APOE |
| intramembranous ossification | biological_process | MMP2 |
| intrinsic apoptotic signaling pathway | biological_process | MSH6, CLU, CDKN1A, TP53, BAX |
| intrinsic apoptotic signaling pathway by p53 class mediator | biological_process | TP53, BAX, FHIT |
| intrinsic apoptotic signaling pathway in response to DNA damage | biological_process | MSH2, MSH6, MLH1, BCL2, TNFRSF1A, PIK3R1, BRCA1, TNFRSF1B, BRCA2, HMOX1, CHEK2, TNF, BCL2L11, BCL2L1, BAX, MCL1, SIRT1, ATM |
| intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological_process | MSH2, CDKN1A, BRCA2, TP53, SIRT1, TP63 |
| intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological_process | GSK3B, BCL2, BAX |
| intrinsic apoptotic signaling pathway in response to oxidative stress | biological_process | BCL2, GPX1, CYP1B1 |
| intussusceptive angiogenesis | biological_process | CYR61 |
| ion homeostasis | biological_process | CRH |
| ion transmembrane transport | biological_process | GJA1, CLCN3, AQP2, S100A6, SGK1, ABCC4, AQP8, ATP7A, AQP5 |
| ion transport | biological_process | ATP5A1, CFTR, CLCN3, ATP5B, LTF, SLC22A23, CP, TF, ATP7A, SLC26A8, TRPV1, P2RX3, SLCO4A1 |
| IRE1-mediated unfolded protein response | biological_process | SHC1 |
| IRES-dependent translational initiation | biological_process | EIF4EBP1 |
| iris morphogenesis | biological_process | WNT2, HIF1A |
| iron assimilation by chelation and transport | biological_process | LTF |
| iron ion homeostasis | biological_process | HMOX1, LTF, TF |
| iron ion transport | biological_process | TF, NECTIN1 |
| isotype switching | biological_process | MSH2, MSH6, MLH1, CD40LG |
| isotype switching to IgG isotypes | biological_process | HSPD1 |
| JAK-STAT cascade | biological_process | STAT3, PRLR, CCL2, CCR2, SOCS3, STAT4, AGER |
| JAK-STAT cascade involved in growth hormone signaling pathway | biological_process | STAT3, MAPK1, PRLR, PRL |
| JNK cascade | biological_process | WNT5A, PTGER4, MAP3K7, TNF, MAP2K7, NOD2, NOD1 |
| keratan sulfate biosynthetic process | biological_process | PRELP, CHST6, CHST2 |
| keratan sulfate catabolic process | biological_process | PRELP |
| keratinization | biological_process | CDH3, CDC42 |
| keratinocyte development | biological_process | CDC42 |
| keratinocyte differentiation | biological_process | YAP1, WNT5A, NOTCH1, CASP3, AKR1C3, ANXA1, LATS1, TP63, JAG1 |
| keratinocyte proliferation | biological_process | TP63 |
| kidney development | biological_process | BCL2, GATA3, VEGFA, BMP4, MME, CTNNB1, SERPINF1, ACE, AGTR1, AGTR2, WT1, HNF1B, BMP6, CA2, FSTL3, BCL2L11, CAT, BAX, SMAD4, PCSK5, WNT4, DCN, TET2 |
| kidney morphogenesis | biological_process | AGTR2, HNF1B, WNT4 |
| killing by host of symbiont cells | biological_process | MBL2 |
| killing of cells of other organism | biological_process | HAMP |
| Kit signaling pathway | biological_process | KIT |
| kynurenic acid biosynthetic process | biological_process | IDO1 |
| L-ascorbic acid metabolic process | biological_process | GCLC |
| L-methionine biosynthetic process from methylthioadenosine | biological_process | ADI1 |
| L-phenylalanine catabolic process | biological_process | GSTZ1 |
| labyrinthine layer blood vessel development | biological_process | MAPK1, AKT1, WNT2, PLCD1, CYR61, HEY1, PLCD3 |
| lacrimal gland development | biological_process | FGFR2 |
| lactate biosynthetic process | biological_process | PARK7 |
| lactate metabolic process | biological_process | HIF1A |
| lactation | biological_process | XDH, CCND1, VEGFA, NME1, VDR, PRLR, OXTR, MT-CO2, PRL, GC, HIF1A, ATP7A, USF2 |
| lamellipodium assembly | biological_process | KIT, RAC1 |
| late viral transcription | biological_process | USF1, USF2 |
| lateral mesoderm development | biological_process | YAP1 |
| lateral sprouting from an epithelium | biological_process | FGFR2 |
| lateral sprouting involved in mammary gland duct morphogenesis | biological_process | WNT5A |
| layer formation in cerebral cortex | biological_process | CTNNB1 |
| leading edge cell differentiation | biological_process | JUN |
| leading strand elongation | biological_process | PCNA |
| learning | biological_process | PTN, COMT, PTGS1, PTGS2, JUN, BCHE, FYN, CLDN5, NTRK2 |
| learning or memory | biological_process | CASP3, CRHBP, STS, TACR1, EGFR, IL1B, CRH, PTEN, ESR2, UCN |
| left lung morphogenesis | biological_process | NODAL |
| left/right axis specification | biological_process | NOTCH1 |
| left/right pattern formation | biological_process | SNAI1 |
| lens development in camera-type eye | biological_process | GATA3, WNT5A, GJA1, WNT2, CRYAB, MAF |
| lens fiber cell development | biological_process | VIM, WNT7A |
| lens fiber cell differentiation | biological_process | TGFB1, SMAD3, MAF |
| lens induction in camera-type eye | biological_process | BMP4 |
| lens morphogenesis in camera-type eye | biological_process | CTNNB1, MEIS1, NECTIN1, NECTIN3 |
| leptin-mediated signaling pathway | biological_process | STAT3, LEP, LEPR, SIRT1, ADIPOR1 |
| leukemia inhibitory factor signaling pathway | biological_process | IL6ST, LIF, LIFR |
| leukocyte activation | biological_process | EDN1 |
| leukocyte adhesive activation | biological_process | CX3CL1 |
| leukocyte cell-cell adhesion | biological_process | CD40LG, CCL5, VCAM1, SELP, SELE, ITGB1, ITGB2, ICAM1 |
| leukocyte chemotaxis | biological_process | IL10, CX3CL1, IL16 |
| leukocyte differentiation | biological_process | ID2 |
| leukocyte homeostasis | biological_process | BCL2, FLT3, BCL2L11, BAX |
| leukocyte migration | biological_process | SRC, ITGA6, ITGA3, PIK3R1, MMP9, MIF, SHC1, CD44, PECAM1, SELP, SELE, PIK3CA, FCER1G, L1CAM, BSG, FN1, ITGB3, ITGB1, ITGAV, TNF, CCL25, FYN, ANGPT2, IL1B, ITGB2, NRAS, KRAS, ICAM1, MMP1, CD74, GAS6, TEK, F2RL1, ANGPT1, GRB14 |
| leukocyte migration involved in inflammatory response | biological_process | CCL2, SELE, ITGB2, ADAM8, CX3CL1 |
| leukocyte proliferation | biological_process | F2RL1 |
| leukocyte tethering or rolling | biological_process | LEP, VCAM1, SELP, SELE, ITGB1, TNF |
| leukotriene metabolic process | biological_process | ALOX15 |
| Leydig cell differentiation | biological_process | CCND1, CYP17A1 |
| limb bud formation | biological_process | FGFR2, SEMA3C |
| limb development | biological_process | NR2F2, CTNNB1, GREM1, WNT7A |
| limb morphogenesis | biological_process | WNT5A, BMPR1B, BAX, PCSK5 |
| lipid biosynthetic process | biological_process | ACLY |
| lipid catabolic process | biological_process | AKR1D1, PLA2G4A, PRDX6, PLCD1, LIPC, PLA2G2A, PLCB1, RARRES3, PLA2G16, PLCB3, PAFAH1B2, PLCD3 |
| lipid digestion | biological_process | LIPC |
| lipid homeostasis | biological_process | CETP, PPARG, USF1, APOE, USF2, IRS2 |
| lipid localization | biological_process | STOML2 |
| lipid metabolic process | biological_process | ATP5A1, AKR1D1, CETP, NR2F2, PLA2G4A, PTGDS, PPARG, PRDX6, CLU, CD36, ALOX15, LEP, HPGD, BRCA1, PLCD1, STS, LIPC, HSD17B1, PLA2G2A, IL1RN, PTGS1, PON1, SRD5A2, PTGS2, HSD17B3, HSD17B2, AKR1C2, ATP5B, CYP11A1, APOA1, APOE, C3, PTGES, CYP1A2, GPX1, PSAP, PTEN, PLCB1, ACLY, PPARA, RARRES3, PLA2G16, HSD17B7, PLCB3, PAFAH1B2, PTGES2, PLCD3, SRD5A1, ADIPOR2, ADIPOR1, SMPD3, PEMT |
| lipid storage | biological_process | CD36, APOA1 |
| lipid transport | biological_process | CETP, STAR, APOA1, APOA2, APOE, PSAP, SCARB1, SFTPA1, SLCO2A1 |
| lipopolysaccharide transport | biological_process | SCARB1 |
| lipopolysaccharide-mediated signaling pathway | biological_process | CCL5, MAPK1, AKT1, CCL3, CCL2, NOS3, TGFB1, TNF, TLR2, TLR4, IL1B, IL18, PTPN22, SCARB1 |
| lipoprotein biosynthetic process | biological_process | APOA1, APOA2, APOE |
| lipoprotein catabolic process | biological_process | APOE, ATM |
| lipoprotein metabolic process | biological_process | CETP, SDC1, APOA1, APOA2, APOE, PPARA, SCARB1 |
| lipoprotein transport | biological_process | PPARG, CD36, PRKCB |
| lipoxin A4 biosynthetic process | biological_process | ALOX15 |
| lipoxin metabolic process | biological_process | HPGD |
| lipoxygenase pathway | biological_process | ALOX15, HPGD, PTGS2, GPX1 |
| liver development | biological_process | CCND1, IGF2R, CTNNB1, NOTCH1, HGF, LIPC, HNF1B, PTN, PIK3CA, JUN, CP, ADA, CYP1A1, SMAD3, RELA, GATA6, WNT4, NODAL, SRD5A1 |
| liver morphogenesis | biological_process | TET2 |
| liver regeneration | biological_process | CCND1, FAS, FGA, CPB2 |
| localization within membrane | biological_process | RAC1 |
| locomotor rhythm | biological_process | PTEN, ID2, NAGLU |
| locomotory behavior | biological_process | OPRM1, DRD2, SOD1, MEIS1, PTEN, NRG1, ATP7A |
| locomotory exploration behavior | biological_process | CRH |
| long term synaptic depression | biological_process | PTEN |
| long-chain fatty acid import | biological_process | CD36 |
| long-chain fatty acid transport | biological_process | PPARG, APOE |
| long-chain fatty-acyl-CoA biosynthetic process | biological_process | ACLY |
| long-term memory | biological_process | DRD2, TACR1, MTOR, NTF4, SGK1, NTRK2 |
| long-term synaptic potentiation | biological_process | MAPK1, BRAF, PTN, CRH, PTEN, NTRK2, CRHR2 |
| loop of Henle development | biological_process | JAG1 |
| low-density lipoprotein particle clearance | biological_process | CD36, HMOX1, LIPC, ADIPOQ, SCARB1 |
| low-density lipoprotein particle mediated signaling | biological_process | CD36 |
| low-density lipoprotein particle receptor biosynthetic process | biological_process | PPARG |
| low-density lipoprotein particle remodeling | biological_process | CETP, AGTR1, LIPC, PLA2G2A, APOA2, APOE, MPO |
| lung alveolus development | biological_process | BMP4, WNT5A, FGFR2, IGFBP5, LIF, PDGFA, ADA, ATP7A, ERRFI1 |
| lung cell differentiation | biological_process | CTNNB1 |
| lung development | biological_process | FGFR1, VEGFA, BMP4, WNT5A, ITGA3, FGFR2, HMGB1, CHI3L1, CTNNB1, WNT2, NOTCH1, SPARC, LIF, MMP14, PTN, NOS3, FGF1, FSTL3, CYP1A2, LAMA5, SPRY2, CP, ADA, CRH, EIF4EBP1, SMAD2, AGER, NODAL, CRISPLD2 |
| lung epithelial cell differentiation | biological_process | YAP1 |
| lung epithelium development | biological_process | ERRFI1 |
| lung goblet cell differentiation | biological_process | AGR2 |
| lung growth | biological_process | SPRY2 |
| lung induction | biological_process | CTNNB1, WNT2 |
| lung lobe development | biological_process | BMP4 |
| lung lobe morphogenesis | biological_process | FGFR2, LIF |
| lung morphogenesis | biological_process | BMP4, MAPK1, ID1, SPRY2 |
| lung saccule development | biological_process | GATA6 |
| lung vasculature development | biological_process | ID1, LIF, ERRFI1 |
| lung-associated mesenchyme development | biological_process | FGFR1, FGFR2, CTNNB1 |
| luteinization | biological_process | PDGFRA, CAPN5, NR5A1 |
| luteinizing hormone signaling pathway | biological_process | LHCGR |
| luteolysis | biological_process | PLA2G4A, MMP13 |
| lymph node development | biological_process | IL15, TGFB1, CXCL13, LTA |
| lymph vessel development | biological_process | NR2F2, FLT4 |
| lymph vessel morphogenesis | biological_process | VEGFA |
| lymphangiogenesis | biological_process | FLT4 |
| lymphocyte chemotaxis | biological_process | CCL5, CCL3, SAA1, CCL2, CCL25, CCL21, CCL22, CCL16, CCL19, ADAM8, CX3CL1, CCL17, CXCL16, CCL11 |
| lymphocyte chemotaxis across high endothelial venule | biological_process | CXCL13 |
| lymphocyte homeostasis | biological_process | BCL2, BCL2L11 |
| lymphocyte migration | biological_process | GATA3, TBX21 |
| lymphocyte migration into lymph node | biological_process | CCR7 |
| lymphocyte proliferation | biological_process | FLT3 |
| lymphoid progenitor cell differentiation | biological_process | BCL2, BMP4, KIT |
| lymphotoxin A biosynthetic process | biological_process | IL17F |
| lysosome organization | biological_process | NAGLU |
| macroautophagy | biological_process | MTOR, GABARAPL1 |
| macrophage activation | biological_process | TLR4, CSF2, FOXP1 |
| macrophage activation involved in immune response | biological_process | HMGB1 |
| macrophage chemotaxis | biological_process | CCL5, LGALS3, CCL3, SAA1, CCL2, CX3CL1 |
| macrophage colony-stimulating factor signaling pathway | biological_process | CSF1, CSF1R, MST1R |
| macrophage cytokine production | biological_process | GAS6, SIRT1 |
| macrophage derived foam cell differentiation | biological_process | TGFB1 |
| macrophage differentiation | biological_process | VEGFA, BMP4, MMP9, CSF1, CSF1R, CDC42, SIRT1 |
| macrophage migration inhibitory factor signaling pathway | biological_process | CD74 |
| maintenance of chromatin silencing | biological_process | ARID1A, HDAC2, SIRT1 |
| maintenance of DNA methylation | biological_process | DNMT1 |
| maintenance of DNA repeat elements | biological_process | MSH2, MSH6 |
| maintenance of gastrointestinal epithelium | biological_process | TLR9, NOD2, MUC4 |
| maintenance of location in cell | biological_process | APOE |
| maintenance of mitotic sister chromatid cohesion | biological_process | RB1 |
| maintenance of permeability of blood-brain barrier | biological_process | PTGS1, PTGS2 |
| maintenance of protein location in cell | biological_process | CD4 |
| maintenance of protein location in mitochondrion | biological_process | AKT1 |
| maintenance of protein location in nucleus | biological_process | NR5A1 |
| male genitalia development | biological_process | CTNNB1, WT1, BMP6, LHCGR, SRD5A2, HSD17B3, SRD5A1 |
| male gonad development | biological_process | MSH2, BCL2, GATA3, INHBA, FSHR, WNT5A, KIT, CTNNA1, KITLG, MMP14, HOXA10, WT1, LHCGR, SRD5A2, HOXA11, AKR1C3, STAR, ESR1, INSR, CYP17A1, INHA, FSTL3, SOX15, TLR3, BCL2L11, LHB, BCL2L1, BAX, NR5A1, ESR2, SMAD4, AMHR2, GATA6, WNT4, SRD5A1 |
| male mating behavior | biological_process | PTEN |
| male meiosis | biological_process | MLH1, PIM2 |
| male meiosis chromosome segregation | biological_process | MLH1 |
| male meiosis I | biological_process | BRCA2 |
| male sex determination | biological_process | INSR |
| male sex differentiation | biological_process | FKBP4 |
| mammary duct terminal end bud growth | biological_process | CSF1, CCL11 |
| mammary gland alveolus development | biological_process | CCND1, VEGFA, PRLR, ESR1, EGF, ID2 |
| mammary gland branching involved in pregnancy | biological_process | VDR, ESR1 |
| mammary gland branching involved in thelarche | biological_process | WNT5A, TGFB1 |
| mammary gland bud formation | biological_process | FGFR2 |
| mammary gland development | biological_process | NME1, BRCA2, ITGA2, TDGF1, TGFB1, BCL2L11, NRG1, IRS2, NOTCH4 |
| mammary gland duct morphogenesis | biological_process | CSF1R |
| mammary gland epithelial cell differentiation | biological_process | AKT1, PRLR |
| mammary gland epithelial cell proliferation | biological_process | CCND1, MAPK1, STAT6, ID2 |
| mammary gland epithelium development | biological_process | WNT2, PRLR, WNT4 |
| mammary gland fat development | biological_process | CSF1 |
| mammary gland formation | biological_process | BMP4 |
| mammary gland involution | biological_process | IGFBP5 |
| mammary gland morphogenesis | biological_process | STAT6 |
| MAPK cascade | biological_process | FGFR1, FGF2, CCL5, MAPK1, FGFR2, KIT, SHC1, CCL3, ERBB3, CCR5, CSF2RB, BRAF, PDGFRA, JAK1, KITLG, CCL2, NCAM1, IL2RB, PSMD9, EGFR, FGF1, TGFB1, TNF, MYC, PDGFA, ERBB2, FYN, PSMD10, IL1B, EGF, NRAS, KRAS, IL2RA, CSF2, IL5, PTK2, NRG1, TEK, PAK1, IL18, IRS2, IL2, ANGPT1, KSR1 |
| MAPK import into nucleus | biological_process | MAPK1 |
| mast cell activation | biological_process | FCER1G |
| mast cell chemotaxis | biological_process | KIT, RAC1, CCL11 |
| mast cell cytokine production | biological_process | KIT |
| mast cell degranulation | biological_process | KIT, GATA2, S100A13 |
| mast cell differentiation | biological_process | GATA3, KIT |
| mast cell proliferation | biological_process | KIT |
| maternal aggressive behavior | biological_process | CRHBP |
| maternal behavior | biological_process | OXTR, PTEN, MBD2 |
| maternal placenta development | biological_process | NR2F2, AKT1, PRDM1, NODAL |
| maternal process involved in female pregnancy | biological_process | AKR1B1, ITGA3, MMP7, FAS, CCL2, LIF, MTOR, ITGB1, LGALS9, ANGPT2, HIF1A, IHH |
| maternal process involved in parturition | biological_process | PTGER4, EDNRA, CCL2, OXTR, PTGER3, CYP1A1, EDN1, NODAL |
| mature conventional dendritic cell differentiation | biological_process | LGALS9, F2RL1, CCL19, CCR7 |
| mature ribosome assembly | biological_process | C1QBP |
| mechanoreceptor differentiation | biological_process | NTF4, NTRK2 |
| megakaryocyte development | biological_process | KIT, MEIS1 |
| megakaryocyte differentiation | biological_process | IL11 |
| meiosis I | biological_process | BCL2L11 |
| meiotic cell cycle | biological_process | H2AFX, AURKA, SLC26A8 |
| meiotic chromosome segregation | biological_process | MLH1 |
| meiotic DNA recombinase assembly | biological_process | XRCC3 |
| meiotic gene conversion | biological_process | MSH2 |
| meiotic metaphase I plate congression | biological_process | MLH1 |
| meiotic mismatch repair | biological_process | MSH2, MSH6 |
| meiotic nuclear division | biological_process | MLH1, MKI67, AURKA |
| meiotic spindle midzone assembly | biological_process | MLH1 |
| meiotic spindle organization | biological_process | AURKA |
| meiotic telomere clustering | biological_process | MLH1, ATM |
| melanin metabolic process | biological_process | BCL2 |
| melanocyte adhesion | biological_process | KIT |
| melanocyte differentiation | biological_process | BCL2, KIT |
| melanocyte migration | biological_process | KIT |
| melanocyte proliferation | biological_process | WNT5A |
| membrane budding | biological_process | ANXA2 |
| membrane depolarization | biological_process | JUN, EDN1, PARK7, ADIPOQ |
| membrane depolarization during action potential | biological_process | YWHAH |
| membrane hyperpolarization | biological_process | CFTR, CASP1, PARK7, ADIPOQ |
| membrane lipid catabolic process | biological_process | CYP1B1 |
| membrane organization | biological_process | YWHAH |
| membrane protein ectodomain proteolysis | biological_process | ADAM17 |
| membrane protein intracellular domain proteolysis | biological_process | NFKB1, RELA, ADAM17 |
| membrane raft assembly | biological_process | ANXA2 |
| membrane to membrane docking | biological_process | VCAM1, ICAM1 |
| membranous septum morphogenesis | biological_process | FGFR2, ID2 |
| memory | biological_process | ITGA3, SLC6A4, PTGS1, OXTR, PTGS2, IGF1, IL1B, IGF2, PTEN, PLCB1, KAT2B |
| menstruation | biological_process | FOXL2 |
| mesangial cell-matrix adhesion | biological_process | CCL21 |
| mesenchymal cell development | biological_process | BCL2, NOTCH1 |
| mesenchymal cell differentiation | biological_process | FGFR1, HMGA2, FGFR2 |
| mesenchymal cell differentiation involved in kidney development | biological_process | BMP4 |
| mesenchymal cell differentiation involved in lung development | biological_process | FGFR2 |
| mesenchymal cell differentiation involved in renal system development | biological_process | BMP4 |
| mesenchymal cell proliferation involved in lung development | biological_process | FGFR2, CTNNB1 |
| mesenchymal cell proliferation involved in ureter development | biological_process | BMP4 |
| mesenchymal cell proliferation involved in ureteric bud development | biological_process | BMP4 |
| mesenchymal to epithelial transition | biological_process | GATA3, WT1, PAX2, WNT4 |
| mesenchymal to epithelial transition involved in metanephros morphogenesis | biological_process | BMP4, GREM1, PAX2 |
| mesenchymal-epithelial cell signaling | biological_process | WNT5A |
| mesenchymal-epithelial cell signaling involved in prostate gland development | biological_process | TNC |
| mesendoderm development | biological_process | NODAL |
| mesoderm development | biological_process | VEGFA, SNAI1, SMAD4 |
| mesoderm formation | biological_process | INHBA, BMP4, SNAI1, DKK1, SMAD3, SMAD2, NODAL |
| mesodermal cell differentiation | biological_process | INHBA, BMP4, HMGA2, ITGA3, FGFR2, ITGA2, ITGB3, ITGB1 |
| mesodermal cell fate determination | biological_process | BMP4 |
| mesodermal cell fate specification | biological_process | HOXA11, PAX2 |
| mesodermal to mesenchymal transition involved in gastrulation | biological_process | WNT5A |
| mesodermal-endodermal cell signaling | biological_process | HMGA2 |
| mesonephric duct development | biological_process | HNF1B |
| mesonephric duct formation | biological_process | HNF1B |
| mesonephric epithelium development | biological_process | FGF1 |
| mesonephric tubule development | biological_process | HNF1B, WNT4 |
| mesonephros development | biological_process | GATA3, BMP4, PAX2, WNT4 |
| metabolic process | biological_process | PLA2G4A, PRDX6, MTHFR, STS, GSTP1, GSTM1, NAT2, HSD3B2, TYMP, ALDH3A2, GSTZ1, CYP26A1, AMY2A, PAK1, ACLY, NAGLU, FOLH1, ARSH, OGG1 |
| metal ion transport | biological_process | ATP7A |
| metanephric collecting duct development | biological_process | BMP4, AQP2, PAX2 |
| metanephric distal convoluted tubule development | biological_process | PAX2 |
| metanephric epithelium development | biological_process | WT1, PAX2 |
| metanephric glomerular capillary formation | biological_process | PDGFRA |
| metanephric mesenchymal cell differentiation | biological_process | PAX2, WNT4 |
| metanephric mesenchyme development | biological_process | WT1, PAX2 |
| metanephric mesenchyme morphogenesis | biological_process | SMAD4 |
| metanephric nephron development | biological_process | WNT4 |
| metanephric nephron morphogenesis | biological_process | WNT4 |
| metanephric nephron tubule formation | biological_process | PAX2 |
| metanephric nephron tubule morphogenesis | biological_process | HES5 |
| metanephric S-shaped body morphogenesis | biological_process | WT1 |
| metanephric tubule formation | biological_process | WNT4 |
| metanephros development | biological_process | BCL2, BMP4, HOXA11, ID2, WNT4 |
| metanephros morphogenesis | biological_process | CTNNB1 |
| metencephalon development | biological_process | WNT1 |
| methionine biosynthetic process | biological_process | ADI1 |
| methionine metabolic process | biological_process | MTHFR |
| methylation | biological_process | DNMT1, COMT, MAT2A, SUV39H1, CYP1A2, PRDM1, DNMT3A, EZH2, EHMT2, DNMT3B, SUV39H2, PEMT |
| methylation-dependent chromatin silencing | biological_process | DNMT3A, SIRT1, MBD2 |
| methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione | biological_process | PARK7 |
| microglial cell activation | biological_process | CLU, IL13, JUN, TLR3, IL4, AIF1, CX3CL1 |
| microglial cell activation involved in immune response | biological_process | TLR3 |
| microglial cell proliferation | biological_process | CLU |
| microtubule bundle formation | biological_process | MAP2, PLK1 |
| microtubule cytoskeleton organization | biological_process | MAP2, AURKA, PTK2 |
| microtubule depolymerization | biological_process | STMN1, SGK1 |
| microtubule polymerization or depolymerization | biological_process | CRYAB |
| microtubule-based movement | biological_process | NGF, KIFAP3 |
| microtubule-based process | biological_process | KIFAP3 |
| midbrain development | biological_process | FGFR1, WNT5A, FGFR2, CTNNB1, CMA1, WNT1 |
| midbrain dopaminergic neuron differentiation | biological_process | WNT2 |
| midbrain morphogenesis | biological_process | DKK1 |
| midbrain-hindbrain boundary development | biological_process | WNT1 |
| midbrain-hindbrain boundary maturation during brain development | biological_process | WNT1 |
| middle ear morphogenesis | biological_process | FGFR1, EDN1, NAGLU |
| midgut development | biological_process | WNT5A, CTNNB1 |
| milk ejection reflex | biological_process | GJA1 |
| mineralocorticoid biosynthetic process | biological_process | HSD3B2 |
| mineralocorticoid receptor signaling pathway | biological_process | GPER1 |
| miRNA loading onto RISC involved in gene silencing by miRNA | biological_process | DICER1 |
| miRNA mediated inhibition of translation | biological_process | STAT3 |
| mismatch repair | biological_process | MSH2, MSH6, MLH1, PCNA, PMS2 |
| mitochondrial ATP synthesis coupled proton transport | biological_process | ATP5A1, ATP5B, STOML2 |
| mitochondrial calcium ion transport | biological_process | STOML2 |
| mitochondrial depolarization | biological_process | CASP1, CDKN2A |
| mitochondrial electron transport, cytochrome c to oxygen | biological_process | MT-CO2 |
| mitochondrial electron transport, NADH to ubiquinone | biological_process | NDUFS1 |
| mitochondrial fragmentation involved in apoptotic process | biological_process | BAX |
| mitochondrial fusion | biological_process | BAX |
| mitochondrial genome maintenance | biological_process | TYMP |
| mitochondrial protein processing | biological_process | STOML2 |
| mitochondrial respiratory chain complex I assembly | biological_process | NDUFS1 |
| mitochondrial transport | biological_process | HSP90AA1 |
| mitochondrion morphogenesis | biological_process | BCL2L1, BAX |
| mitochondrion organization | biological_process | NOS3, ATP5B, TERT, PARK7, STOML2, ATP7A, PPRC1 |
| mitophagy | biological_process | GABARAPL1, CDKN2A |
| mitophagy in response to mitochondrial depolarization | biological_process | ANXA5, PIK3CA, MSTN, C5, SFRP4 |
| mitotic cell cycle | biological_process | CCNB1, AURKA, PAK4, DNMT3A, PAK1 |
| mitotic cell cycle arrest | biological_process | CDKN1B, CDKN1A |
| mitotic cell cycle checkpoint | biological_process | TGFB1, RB1, BCL2L1 |
| mitotic centrosome separation | biological_process | AURKA |
| mitotic cleavage furrow formation | biological_process | RHOA |
| mitotic cytokinesis | biological_process | STMN1, PLK1 |
| mitotic G1 DNA damage checkpoint | biological_process | CCND1, TP53, TP63 |
| mitotic G2 DNA damage checkpoint | biological_process | HMGA2 |
| mitotic metaphase plate congression | biological_process | CCNB1 |
| mitotic nuclear division | biological_process | HMGA2, CCNB1, HGF, CHEK2, AURKA, BIRC5, LATS1, NR3C1, PLK1, FSD1 |
| mitotic nuclear envelope disassembly | biological_process | CCNB1, PRKCB, PLK1 |
| mitotic recombination-dependent replication fork processing | biological_process | BRCA2 |
| mitotic sister chromatid segregation | biological_process | PLK1 |
| mitotic spindle assembly | biological_process | CHEK2, BIRC5, RHOA |
| mitotic spindle assembly checkpoint | biological_process | PLK1, ATM |
| mitotic spindle organization | biological_process | CCNB1, STMN1, AURKA |
| mitotic telomere maintenance via semi-conservative replication | biological_process | PCNA |
| mitral valve formation | biological_process | NOTCH1 |
| mitral valve morphogenesis | biological_process | EFNA1, TWIST1 |
| modulation of synaptic transmission | biological_process | DRD2 |
| monoamine transport | biological_process | SLC6A4, SLC6A2 |
| monocarboxylic acid metabolic process | biological_process | CYP1A2 |
| monocarboxylic acid transport | biological_process | BSG |
| monocyte activation | biological_process | CSF1, FOXP1 |
| monocyte aggregation | biological_process | CD44, IL1B |
| monocyte chemotaxis | biological_process | CCL5, LGALS3, CCL3, IL6R, FLT1, CCL2, ANXA1, CCL25, CCL21, CCL22, CCL16, IL6, CCL19, CCL7, CX3CL1, CCL17, CCL11 |
| monocyte differentiation | biological_process | VEGFA, BMP4, PPARG, JUN, CSF1R |
| mononuclear cell migration | biological_process | LGALS3 |
| mononuclear cell proliferation | biological_process | ACE, TGFB1 |
| monosaccharide metabolic process | biological_process | AKR1B1 |
| monoterpenoid metabolic process | biological_process | CYP2C19, CYP2E1, CYP1A2 |
| monovalent inorganic cation transport | biological_process | ATP1B4 |
| morphogenesis of a branching structure | biological_process | TDGF1, TGFB1, PRDM1, NOTCH4 |
| morphogenesis of a polarized epithelium | biological_process | LAMA5, TP63 |
| morphogenesis of an epithelial fold | biological_process | EGFR |
| morphogenesis of an epithelial sheet | biological_process | HOXB2, JAG1 |
| morphogenesis of an epithelium | biological_process | WNT5A, CA2 |
| morphogenesis of embryonic epithelium | biological_process | FGFR2, CTNNB1, VEGFC, TGFB1I1, LAMA5 |
| motogenic signaling involved in postnatal olfactory bulb interneuron migration | biological_process | FGFR1 |
| motor learning | biological_process | DKK1 |
| motor neuron apoptotic process | biological_process | FAS |
| motor neuron axon guidance | biological_process | ERBB2, NRP1, SEMA3A |
| movement of cell or subcellular component | biological_process | TXN, STAT3, VIM, CXCL8, FPR1, CXCR3, IL13, PTGS2, IGF1, IFNG, HSPB1, TPM3, PAK4, RAC1, PLAUR, ACTB, MST1R, IGSF8, NPY, CALD1 |
| mRNA processing | biological_process | LGALS3, C1QBP, YBX1 |
| mRNA splicing, via spliceosome | biological_process | YBX1, ELAVL1 |
| mRNA stabilization | biological_process | MTOR, ELAVL1 |
| mRNA transcription | biological_process | HSF1 |
| mRNA transcription from RNA polymerase II promoter | biological_process | ARNT, HIF1A, POU5F1 |
| mucus secretion | biological_process | AGR2 |
| Mullerian duct regression | biological_process | AMH, AMHR2 |
| multicellular organism aging | biological_process | EDN1, NR5A1, TP63 |
| multicellular organism development | biological_process | GSK3B, FGF2, VEGFA, BMP4, CDX1, WNT5A, HMGA2, AKT1, SERPINF1, WNT2, NOTCH1, KDR, ID1, VDR, TNFRSF1B, CD40, PDGFRA, FLT1, CNTF, PAEP, CFC1B, LEPR, VCAN, HOXB2, LIF, STMN1, HOXA10, TYMP, MDK, BMP6, MMP11, HOXA11, L1CAM, SOX2, VEGFC, EGFR, FGF1, ANG, TP53, TNF, PDGFA, FYN, MEIS1, WNT7A, SNAI1, NRP1, ANGPT2, SPRY2, FIGF, NRP2, DKK1, IGF2, PRM1, WNT1, CSF1R, PTK2, NTRK2, HES5, DPYSL2, HEY1, MCL1, POU5F1, ELAVL1, SIRT1, ID2, TWIST1, CADM1, TP63, EMX2, NAA15, SLC26A8, JAG1, PAX2, DLX5, WNT4, DLL4, ANGPT1, SEMA3A, IHH, SFRP4, TBPL2, NOTCH4, CCL17, NODAL, OLFM1, SEMA3C, NANOG, TBX21, CHST2, TET3, CREB3L1, SMPD3 |
| multicellular organism growth | biological_process | FGFR2, BRCA2, MTOR, CDC42 |
| multicellular organismal iron ion homeostasis | biological_process | BMP6, HAMP |
| multicellular organismal macromolecule metabolic process | biological_process | AKR1C3 |
| multicellular organismal reproductive process | biological_process | COMT |
| multicellular organismal response to stress | biological_process | LGALS1, IDO1, PTEN |
| muscle cell cellular homeostasis | biological_process | SOD1, MSTN, IL6, HIF1A |
| muscle contraction | biological_process | GJA1, ITGB5, TACR2, OXTR, CRYAB, TPM3, TMOD3, CALD1 |
| muscle fiber development | biological_process | UCHL1 |
| muscle filament sliding | biological_process | VIM, TPM3 |
| muscle hypertrophy | biological_process | IGF1 |
| muscle organ development | biological_process | IGF1, CRYAB, CXCL10, MSTN, LAMA5, NRG1, SIRT1, TWIST1, TAGLN |
| muscle organ morphogenesis | biological_process | CNTF, LIF |
| MyD88-dependent toll-like receptor signaling pathway | biological_process | HSPD1, CD36, MAP3K7, TLR2, TLR4, TLR9 |
| MyD88-independent toll-like receptor signaling pathway | biological_process | TLR4, TLR3 |
| myelin maintenance | biological_process | CXCR4 |
| myelination | biological_process | TGFB1, ERBB2, TNFRSF21, NRG1 |
| myelination in peripheral nervous system | biological_process | ADAM22 |
| myeloid cell differentiation | biological_process | BCL6, TET2 |
| myeloid cell homeostasis | biological_process | SOD1, BCL2L11, IL6, BAX, FOXP3 |
| myeloid dendritic cell activation | biological_process | HMGB1 |
| myeloid dendritic cell chemotaxis | biological_process | CCL19, CCR7 |
| myeloid dendritic cell differentiation | biological_process | TGFB1, CSF2, IL4 |
| myeloid leukocyte differentiation | biological_process | KIT |
| myeloid progenitor cell differentiation | biological_process | KIT, BRAF, FLT3, TET2 |
| myoblast development | biological_process | SDC1, SOX15 |
| myoblast differentiation | biological_process | CTNNB1, LGALS1, IGF1, RB1, JAG1 |
| myoblast fusion | biological_process | GSK3B, WNT1 |
| myoblast migration involved in skeletal muscle regeneration | biological_process | ANXA1 |
| myoblast proliferation | biological_process | HGF, IGF1, GPX1 |
| myofibril assembly | biological_process | TMOD3 |
| myotube cell development | biological_process | IGF1 |
| myotube differentiation | biological_process | GSK3B, GPX1, WNT1 |
| N-acetylglucosamine metabolic process | biological_process | CHST6, CHST2 |
| N-terminal peptidyl-lysine acetylation | biological_process | KAT2B |
| N-terminal peptidyl-methionine acetylation | biological_process | NAA15 |
| N-terminal protein amino acid acetylation | biological_process | NAA15 |
| NAD biosynthesis via nicotinamide riboside salvage pathway | biological_process | PNP |
| nail development | biological_process | ITGA6 |
| naphthalene metabolic process | biological_process | AKR1B1 |
| natural killer cell activation | biological_process | IL12B, IL2RB, NCR1, ITGB2, IL18, IL2, ULBP2, KLRK1, KIR3DS1 |
| natural killer cell activation involved in immune response | biological_process | IL12B |
| natural killer cell differentiation | biological_process | AXL, IL15, TYRO3, ID2 |
| natural killer cell inhibitory signaling pathway | biological_process | KIR2DL1 |
| natural killer cell mediated cytotoxicity | biological_process | KIR3DL1, MICA, MICB, ULBP2 |
| natural killer cell mediated immunity | biological_process | KLRD1 |
| natural killer cell tolerance induction | biological_process | LGALS9 |
| necroptotic process | biological_process | FASLG, TLR4, TLR3 |
| necroptotic signaling pathway | biological_process | FASLG, FAS, TNF, TLR3 |
| negative chemotaxis | biological_process | WNT5A, ITGB3, ITGAV, APOA1, PDGFA, SEMA3A, SEMA3C, RHOA |
| negative regulation by host of viral exo-alpha-sialidase activity | biological_process | PTX3, APCS |
| negative regulation by host of viral glycoprotein metabolic process | biological_process | PTX3, APCS |
| negative regulation by host of viral process | biological_process | LTF |
| negative regulation by host of viral transcription | biological_process | HMGA2, CCL5, CCL3, JUN, HDAC1 |
| negative regulation of activated T cell proliferation | biological_process | CASP3, LGALS9, FOXP3 |
| negative regulation of activin receptor signaling pathway | biological_process | FST, FSTL3 |
| negative regulation of acute inflammatory response | biological_process | PPARG, GSTP1, APCS, IL4 |
| negative regulation of adaptive immune response | biological_process | ALOX15 |
| negative regulation of adenosine receptor signaling pathway | biological_process | ADA |
| negative regulation of adenylate cyclase activity | biological_process | OPRM1, DRD2, CCR2 |
| negative regulation of adiponectin secretion | biological_process | IL1B |
| negative regulation of alkaline phosphatase activity | biological_process | TNF, TGFB2 |
| negative regulation of alpha-beta T cell activation | biological_process | LILRB1 |
| negative regulation of alpha-beta T cell differentiation | biological_process | IHH |
| negative regulation of androgen receptor signaling pathway | biological_process | FOXP1, HDAC1, SIRT1, NODAL |
| negative regulation of angiogenesis | biological_process | SERPINF1, FASLG, CXCR3, COL4A2, SPARC, CCL2, LIF, PTN, CCR2, CXCL10, ANGPT2, THBS1, KLK3, TEK, GHRL, IL17F, DCN |
| negative regulation of anoikis | biological_process | BCL2, SRC, NOTCH1, PIK3CA, ITGB1, PTK2, BCL2L1, NTRK2, MCL1 |
| negative regulation of anti-Mullerian hormone signaling pathway | biological_process | AMHR2 |
| negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological_process | THBS1 |
| negative regulation of apoptotic cell clearance | biological_process | HMGB1 |
| negative regulation of apoptotic process | biological_process | GCLC, GSK3B, BCL2, HSPD1, SRC, VEGFA, BCL6, STAT3, BMP4, CD40LG, WNT5A, HMGA2, CLU, PIK3R1, IL10, LEP, MMP9, MIF, ANXA5, AKT1, EPCAM, CFL1, NFKB1, CDKN1B, KDR, ID1, CASP3, FLT4, CDKN1A, BRAF, CTNNA1, AXL, ANXA4, PRLR, IL6ST, EDNRA, HGF, GSTP1, CD44, KITLG, FAS, TDGF1, IL2RB, WT1, HNF1B, PTGFR, FN1, AURKA, IGF1, GREM1, EGFR, JUN, CRYAB, ANXA1, SOD1, IGF1R, NGF, TIMP1, LTF, TP53, MYC, HSPB1, BIRC5, SGK1, CYR61, WNT7A, SOCS3, SPRY2, THBS1, PSMD10, CLDN7, GPX1, ADA, CAT, CD74, IL4, SERPINB2, MPO, IL6, CSF1R, PTEN, PLK1, PTK2, HDAC2, SMAD3, RELA, BCL2L1, PARK7, HIF1A, FOXO1, GAS6, PLAUR, TEK, GHRL, AIF1, MCL1, HDAC1, KIFAP3, SIRT1, TWIST1, DAPK1, PIM2, TP63, GATA6, NAA15, PAX2, UCN, IL2, DAD1, ANGPT1, IHH, ATAD3A, OGG1 |
| negative regulation of apoptotic process involved in metanephric collecting duct development | biological_process | PAX2 |
| negative regulation of apoptotic process involved in metanephric nephron tubule development | biological_process | PAX2 |
| negative regulation of apoptotic signaling pathway | biological_process | BCL2, CTNNB1, HSPB1, BAX, WNT4 |
| negative regulation of appetite | biological_process | LEP, PPARA, UCN |
| negative regulation of appetite by leptin-mediated signaling pathway | biological_process | LEP |
| negative regulation of astrocyte differentiation | biological_process | HES5 |
| negative regulation of ATPase activity | biological_process | LTF |
| negative regulation of auditory receptor cell differentiation | biological_process | NOTCH1 |
| negative regulation of autophagy | biological_process | BCL2, MET, LEP, AKT1, HGF, LEPR, MTOR, BCL2L1, PTPN22 |
| negative regulation of axon extension | biological_process | CCR2, NRP1, SEMA3A |
| negative regulation of axon extension involved in axon guidance | biological_process | WNT5A, NRP1, SEMA3A, SEMA3C |
| negative regulation of axonogenesis | biological_process | PTEN, PTK2, RHOA |
| negative regulation of B cell activation | biological_process | FAS |
| negative regulation of B cell apoptotic process | biological_process | BCL6, FOXP1, IRS2, IL2 |
| negative regulation of B cell differentiation | biological_process | INHBA, INHA, ID2 |
| negative regulation of B cell proliferation | biological_process | IL10, CASP3, CTLA4, TNFRSF21, PRDM1, ATM, CDKN2A |
| negative regulation of behavior | biological_process | ESR2 |
| negative regulation of beta-amyloid formation | biological_process | CLU, APOE |
| negative regulation of bicellular tight junction assembly | biological_process | TNF |
| negative regulation of binding of sperm to zona pellucida | biological_process | OVGP1 |
| negative regulation of biomineral tissue development | biological_process | AHSG, GAS6 |
| negative regulation of biosynthetic process | biological_process | GSTP1 |
| negative regulation of blood coagulation | biological_process | ANXA5, APOE, SERPINE1, EDN1 |
| negative regulation of blood coagulation, common pathway | biological_process | FGA |
| negative regulation of blood pressure | biological_process | NOS2, DRD2, NOS3, VEGFC, CRH, ADIPOQ, PPARA, UCN |
| negative regulation of blood vessel endothelial cell migration | biological_process | FGF2, HMGB1, AGTR2, TGFB1, APOE, ANGPT2, THBS1, DLL4 |
| negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological_process | DLL4 |
| negative regulation of BMP signaling pathway | biological_process | WNT5A, TOB1, NOTCH1, GREM1, FSTL3, SMAD7, DKK1, WNT1, HTRA1 |
| negative regulation of bone mineralization | biological_process | CCL3, CCR1, GREM1, AHSG, HIF1A |
| negative regulation of bone mineralization involved in bone maturation | biological_process | GREM1 |
| negative regulation of bone remodeling | biological_process | GREM1 |
| negative regulation of bone resorption | biological_process | TNFRSF11B |
| negative regulation of bone trabecula formation | biological_process | GREM1 |
| negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway | biological_process | BMP4 |
| negative regulation of branching involved in lung morphogenesis | biological_process | TNF |
| negative regulation of branching involved in ureteric bud morphogenesis | biological_process | BMP4, GREM1 |
| negative regulation of branching morphogenesis of a nerve | biological_process | IL1B |
| negative regulation of calcidiol 1-monooxygenase activity | biological_process | NFKB1 |
| negative regulation of calcium ion import | biological_process | SPINK1, CRHR2 |
| negative regulation of calcium ion transmembrane transport | biological_process | PTGER3 |
| negative regulation of calcium ion transport | biological_process | NOS3, PTGS2, ICAM1, STC1, LILRB1 |
| negative regulation of calcium ion transport into cytosol | biological_process | BCL2 |
| negative regulation of calcium ion-dependent exocytosis | biological_process | NOTCH1 |
| negative regulation of calcium-transporting ATPase activity | biological_process | TLR9 |
| negative regulation of cAMP biosynthetic process | biological_process | OPRM1, EDNRA, PTGER3, EDN1, CRHR2 |
| negative regulation of cAMP-dependent protein kinase activity | biological_process | SIRT1 |
| negative regulation of cAMP-mediated signaling | biological_process | OPRM1 |
| negative regulation of canonical Wnt signaling pathway | biological_process | GSK3B, EGR1, WNT5A, IGFBP2, NOTCH1, IGFBP1, IGFBP4, SOX2, PSMD9, GREM1, APOE, LATS1, DKK1, PSMD10, FOXO1, HDAC1, WNT4, SFRP4 |
| negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | biological_process | DKK1 |
| negative regulation of cardiac muscle cell apoptotic process | biological_process | NRG1 |
| negative regulation of cardiac muscle cell differentiation | biological_process | DKK1 |
| negative regulation of cardiac muscle cell proliferation | biological_process | GJA1 |
| negative regulation of cardiac muscle hypertrophy | biological_process | GSK3B |
| negative regulation of cardiac muscle hypertrophy in response to stress | biological_process | ERRFI1 |
| negative regulation of cartilage development | biological_process | LEP, TGFB2 |
| negative regulation of catagen | biological_process | CDH3 |
| negative regulation of catalytic activity | biological_process | ANXA5, NOTCH1, ANXA4, PTN, TIMP1, ANXA2, SET, ATP7A, TIMP4 |
| negative regulation of cation channel activity | biological_process | MMP9 |
| negative regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | HMGB1 |
| negative regulation of CD4-positive, alpha-beta T cell proliferation | biological_process | LGALS9 |
| negative regulation of CD8-positive, alpha-beta T cell activation | biological_process | LILRB1 |
| negative regulation of cell adhesion | biological_process | FBLN1, PIK3R1, ERBB3, TNC, CLDN7, AGER, ADAM22, ANGPT1 |
| negative regulation of cell adhesion involved in substrate-bound cell migration | biological_process | ATP5B |
| negative regulation of cell adhesion mediated by integrin | biological_process | MUC1, SERPINE1, CYP1B1 |
| negative regulation of cell adhesion molecule production | biological_process | APOA1 |
| negative regulation of cell aging | biological_process | MIF, WNT1, PTEN |
| negative regulation of cell cycle | biological_process | GATA3, INHBA, BMP4, HPGD, CASP3, PTGS2, TGFB1, INHA, RB1, RUNX3, PLA2G16, LILRB1 |
| negative regulation of cell cycle arrest | biological_process | CCND1, MIF, CHEK2, GPER1 |
| negative regulation of cell cycle process | biological_process | GPER1 |
| negative regulation of cell death | biological_process | FGF2, STAT3, BMP4, CCL5, NOTCH1, NTF4, CYR61, CTSB, AGR2, CRH, PARK7, NFE2L2, ESR2, SMAD4, UCN |
| negative regulation of cell development | biological_process | NODAL |
| negative regulation of cell differentiation | biological_process | BCL6, MAPK1, CTNNB1, NOTCH1, ITGB1, TGFB1, KRAS, WNT1, TWIST1, JAG1, WNT4, NOTCH4, NODAL |
| negative regulation of cell differentiation involved in embryonic placenta development | biological_process | SNAI1 |
| negative regulation of cell division | biological_process | MYC |
| negative regulation of cell growth | biological_process | BCL2, INHBA, BCL6, PPARG, GJA1, CDKN1B, CDKN1A, CDKN2A, AGTR2, WT1, GREM1, CRYAB, TGFB1, TP53, ENO1, GDF9, TGFB2, SMAD3, ESR2, SIRT1, SMAD4, TRO, ADIPOR2, ADIPOR1, RERG |
| negative regulation of cell migration | biological_process | BCL2, DRD2, ENG, IGFBP5, PTN, CCR2, SMAD7, SERPINE1, PTEN, ADIPOQ, IL24, WNT4, CYP1B1, STC1 |
| negative regulation of cell migration involved in sprouting angiogenesis | biological_process | NOTCH1, DLL4, RHOA |
| negative regulation of cell motility | biological_process | GATA3, FBLN1, CTNNA1 |
| negative regulation of cell projection organization | biological_process | ITGA3, ITGB1, SPRY2 |
| negative regulation of cell proliferation | biological_process | BCL2, GATA3, INHBA, BCL6, STAT3, BMP4, F2R, PPARG, GJA1, IGFBP3, CXCL8, OPRM1, CTNNB1, HMGA1, AR, TOB1, CDKN1B, NOTCH1, NME1, DRD2, CDKN1A, CDKN2A, VDR, CXCL1, HMOX1, AZGP1, LIF, TIMP2, WT1, NOS3, SSTR1, ADM, SSTR5, PTGS2, VEGFC, ZEB1, COL18A1, RARRES1, ITGB1, JUN, IFNG, TGFB1, IL1A, BCHE, TP53, PTGES, RB1, KLF11, TGFB1I1, SPRY2, IL1B, IL6, CSF1R, PTEN, TGFB2, SMAD3, BAX, HSF1, SMAD2, KAT2B, FOXP3, KIFAP3, SMAD4, RARRES3, GPER1, PIM2, IL1RL1, IL24, IGFBP7, KLF10, DLL4, SST, KISS1R, KISS1, CYP1B1, SFRP4, CHD5, RERG, PEMT |
| negative regulation of cell proliferation in midbrain | biological_process | WNT5A |
| negative regulation of cell proliferation involved in contact inhibition | biological_process | PAK1 |
| negative regulation of cell proliferation involved in heart morphogenesis | biological_process | BMP4 |
| negative regulation of cell proliferation involved in mesonephros development | biological_process | GATA3 |
| negative regulation of cell size | biological_process | AKT1, MTOR, PTEN, UCN |
| negative regulation of cell volume | biological_process | CLCN3 |
| negative regulation of cell-cell adhesion | biological_process | CDH1, TGFB1, WNT1, PTK2 |
| negative regulation of cell-cell adhesion mediated by cadherin | biological_process | EPCAM |
| negative regulation of cell-matrix adhesion | biological_process | BCL6, PIK3R1, CDKN2A, THBS1, POSTN |
| negative regulation of cell-substrate adhesion | biological_process | NOTCH1, LGALS1, ANGPT2, WNT1 |
| negative regulation of cellular component movement | biological_process | CDKN1B, ACTN4 |
| negative regulation of cellular pH reduction | biological_process | BCL2 |
| negative regulation of cellular protein metabolic process | biological_process | MIF, NFKB1, EDN1 |
| negative regulation of cellular response to testosterone stimulus | biological_process | SIRT1 |
| negative regulation of cellular senescence | biological_process | BCL6, TERT, SIRT1, TWIST1, TP63 |
| negative regulation of centriole replication | biological_process | BRCA1 |
| negative regulation of cerebellar granule cell precursor proliferation | biological_process | SLC6A4 |
| negative regulation of cGMP-mediated signaling | biological_process | THBS1 |
| negative regulation of chemokine (C-C motif) ligand 5 production | biological_process | IL10 |
| negative regulation of chemokine biosynthetic process | biological_process | IL6 |
| negative regulation of chemokine production | biological_process | LGALS9 |
| negative regulation of chemokine secretion | biological_process | F2RL1 |
| negative regulation of chemokine-mediated signaling pathway | biological_process | CCL5 |
| negative regulation of cholangiocyte apoptotic process | biological_process | MTOR, IGF1 |
| negative regulation of cholesterol biosynthetic process | biological_process | SOD1, APOE |
| negative regulation of cholesterol efflux | biological_process | APOE, EGF |
| negative regulation of cholesterol import | biological_process | APOA2 |
| negative regulation of cholesterol storage | biological_process | PPARG, PPARA |
| negative regulation of cholesterol transport | biological_process | NFKB1, APOA2 |
| negative regulation of cholesterol transporter activity | biological_process | APOA2 |
| negative regulation of chondrocyte differentiation | biological_process | BMP4, CTNNB1, GREM1 |
| negative regulation of chondrocyte proliferation | biological_process | BMPR1B |
| negative regulation of chorionic trophoblast cell proliferation | biological_process | NODAL |
| negative regulation of chromatin silencing | biological_process | HMGA1 |
| negative regulation of chronic inflammatory response | biological_process | CYP19A1, IL4, FOXP3 |
| negative regulation of chronic inflammatory response to antigenic stimulus | biological_process | IL10 |
| negative regulation of circadian rhythm | biological_process | SUV39H1, SUV39H2 |
| negative regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | ADA |
| negative regulation of circadian sleep/wake cycle, REM sleep | biological_process | PTGER4, CRH, GHRL |
| negative regulation of circadian sleep/wake cycle, sleep | biological_process | DRD2 |
| negative regulation of circadian sleep/wake cycle, wakefulness | biological_process | PTGER3 |
| negative regulation of coagulation | biological_process | ANXA5 |
| negative regulation of collagen biosynthetic process | biological_process | PPARG, IL6R, IL6, ERRFI1, AGER |
| negative regulation of collateral sprouting of intact axon in response to injury | biological_process | SPP1 |
| negative regulation of complement activation, classical pathway | biological_process | C4BPA |
| negative regulation of complement activation, lectin pathway | biological_process | A2M |
| negative regulation of complement-dependent cytotoxicity | biological_process | IL13, IL4 |
| negative regulation of corticotropin secretion | biological_process | CRHBP |
| negative regulation of corticotropin-releasing hormone receptor activity | biological_process | CRHBP |
| negative regulation of CREB transcription factor activity | biological_process | FOXP3 |
| negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological_process | NR2F2, CDKN1B, CASP3, CDKN1A, CDKN2A, LATS1, PLK1, KAT2B |
| negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological_process | PTEN |
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | SRC, VEGFA, AKT1, HGF, CD44, CRYAB, NGF, BIRC5, THBS1, GPX1, IL6, GAS6, PAX2 |
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological_process | MMP9, PARK7, PLAUR |
| negative regulation of cytokine activity | biological_process | IL10 |
| negative regulation of cytokine biosynthetic process | biological_process | TIA1, FOXP3 |
| negative regulation of cytokine production | biological_process | IL10, NFKB1 |
| negative regulation of cytokine secretion | biological_process | PTGER4, IL6, FOXP3, CX3CL1 |
| negative regulation of cytokine secretion involved in immune response | biological_process | IL10, APOA1, APOA2, TNF, ANGPT1, LILRB1 |
| negative regulation of cytokine-mediated signaling pathway | biological_process | IL1RN |
| negative regulation of cytolysis | biological_process | CSF2, PAX2 |
| negative regulation of cytosolic calcium ion concentration | biological_process | OPRM1, DRD2 |
| negative regulation of death-inducing signaling complex assembly | biological_process | PARK7 |
| negative regulation of defecation | biological_process | CRHR2 |
| negative regulation of defense response to virus | biological_process | IL2RA, C1QBP, HTRA1 |
| negative regulation of defense response to virus by host | biological_process | MICB |
| negative regulation of dendrite development | biological_process | GSK3B |
| negative regulation of dendrite morphogenesis | biological_process | GSK3B, ID1, YWHAH |
| negative regulation of dendritic cell antigen processing and presentation | biological_process | THBS1 |
| negative regulation of dendritic cell apoptotic process | biological_process | AXL, GAS6, LILRB1 |
| negative regulation of dendritic cell dendrite assembly | biological_process | CCL21 |
| negative regulation of dendritic cell differentiation | biological_process | HLA-G, LILRB1 |
| negative regulation of dendritic spine development | biological_process | APOE, HDAC2 |
| negative regulation of dendritic spine maintenance | biological_process | APOE |
| negative regulation of dendritic spine morphogenesis | biological_process | EFNA1, PTEN |
| negative regulation of DNA binding | biological_process | HMGA2, ID1, HMOX1, JUN, HDAC2, ID2 |
| negative regulation of DNA biosynthetic process | biological_process | GJA1, ADIPOQ |
| negative regulation of DNA damage checkpoint | biological_process | CHEK2 |
| negative regulation of DNA damage response, signal transduction by p53 class mediator | biological_process | MIF, CD44, SNAI1, PSMD10, CD74, SIRT1, TWIST1 |
| negative regulation of DNA demethylation | biological_process | GATA3 |
| negative regulation of DNA metabolic process | biological_process | GPER1 |
| negative regulation of DNA recombination | biological_process | MSH2, MSH6 |
| negative regulation of DNA replication | biological_process | TGFB1 |
| negative regulation of dopamine metabolic process | biological_process | COMT |
| negative regulation of dopamine receptor signaling pathway | biological_process | DRD2 |
| negative regulation of dopamine secretion | biological_process | DRD2 |
| negative regulation of dopaminergic neuron differentiation | biological_process | GSK3B |
| negative regulation of double-strand break repair | biological_process | TWIST1 |
| negative regulation of double-strand break repair via nonhomologous end joining | biological_process | HMGA2 |
| negative regulation of double-strand break repair via single-strand annealing | biological_process | OGG1 |
| negative regulation of ductus arteriosus closure | biological_process | PTGER4 |
| negative regulation of endocytosis | biological_process | LGALS3, LILRB1 |
| negative regulation of endodermal cell differentiation | biological_process | COL5A2 |
| negative regulation of endopeptidase activity | biological_process | AKT1, SERPINF1, C4A, TIMP2, SERPINA6, A2M, SERPINA1, AHSG, TIMP1, C3, SLPI, SERPINE1, C5, SERPINB2, WFDC2, TIMP4 |
| negative regulation of endoplasmic reticulum calcium ion concentration | biological_process | BAX |
| negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological_process | PARK7, CREB3L1 |
| negative regulation of endothelial cell apoptotic process | biological_process | GATA3, IL10, KDR, BRAF, IL11, IL13, FGA, SERPINE1, ICAM1, IL4, GAS6, TEK, NFE2L2, ANGPT1 |
| negative regulation of endothelial cell chemotaxis | biological_process | NOTCH1, THBS1 |
| negative regulation of endothelial cell chemotaxis to fibroblast growth factor | biological_process | CXCL13 |
| negative regulation of endothelial cell differentiation | biological_process | XDH, ID1, NOTCH4 |
| negative regulation of endothelial cell migration | biological_process | NR2F2, SERPINF1, THBS1, AGER, DLL4, DCN, STC1 |
| negative regulation of endothelial cell proliferation | biological_process | XDH, ATP5A1, NR2F2, GJA1, CXCR3, ENG, SPARC, APOE, THBS1, GHRL, AGER |
| negative regulation of endothelin secretion | biological_process | PTGER4 |
| negative regulation of energy homeostasis | biological_process | GHRL |
| negative regulation of entry of bacterium into host cell | biological_process | ITGAV |
| negative regulation of eosinophil degranulation | biological_process | CCR2 |
| negative regulation of eosinophil extravasation | biological_process | PTGER4 |
| negative regulation of epidermal cell differentiation | biological_process | EZH2 |
| negative regulation of epidermal growth factor receptor signaling pathway | biological_process | EGFR, SPRY2, EGF, CDC42, ERRFI1 |
| negative regulation of epidermal growth factor-activated receptor activity | biological_process | ERRFI1 |
| negative regulation of epinephrine secretion | biological_process | PTGS1, CRH, CRHR2 |
| negative regulation of epithelial cell differentiation | biological_process | YAP1, CCND1, ZEB1, IFNG |
| negative regulation of epithelial cell migration | biological_process | IL4, PTPRR, SEMA3A |
| negative regulation of epithelial cell proliferation | biological_process | BMP4, WNT5A, FGFR2, ATF2, CDKN1B, PTN, SOX2, TGFB1, RB1, PTEN, RUNX3, TGFB2, ESR2 |
| negative regulation of epithelial cell proliferation involved in prostate gland development | biological_process | SERPINF1, CDKN1B |
| negative regulation of epithelial to mesenchymal transition | biological_process | EFNA1, SMAD7 |
| negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | TGFB2 |
| negative regulation of ERK1 and ERK2 cascade | biological_process | FBLN1, GSTP1, LIF, TIMP3, TLR4, SPRY2, PTEN, ADIPOQ, ERRFI1, GPER1, PTPRR |
| negative regulation of establishment of protein localization to plasma membrane | biological_process | BCL2L1 |
| negative regulation of excitatory postsynaptic potential | biological_process | PTEN |
| negative regulation of execution phase of apoptosis | biological_process | CXCR3, BCL2L1 |
| negative regulation of exo-alpha-sialidase activity | biological_process | PTX3, APCS |
| negative regulation of exocytosis | biological_process | ANXA1 |
| negative regulation of extracellular matrix disassembly | biological_process | TGFB1 |
| negative regulation of extrinsic apoptotic signaling pathway | biological_process | GCLC, SRC, ITGA6, YAP1, LGALS3, AR, GSTP1, IGF1, ITGAV, NRP1, THBS1, IL4, RELA, PARK7 |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological_process | BCL2, AKT1, CTNNA1, IL1A, TNF, TERT, FYN, IL1B, CSF2, NRG1, BCL2L1, MCL1, CX3CL1 |
| negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological_process | BRCA1, TNFSF10, FASLG, HGF, HMOX1, FAS, NOS3, FGA, SERPINE1, GPX1, ICAM1, DAPK1 |
| negative regulation of fat cell differentiation | biological_process | GATA3, WNT5A, GATA2, MMP11, TGFB1, TNF, TGFB1I1, WNT1, IL6, SMAD3, FOXO1, ADIPOQ, SIRT1, GPER1, JAG1 |
| negative regulation of fat cell proliferation | biological_process | GATA2 |
| negative regulation of fatty acid beta-oxidation | biological_process | AKT1 |
| negative regulation of fatty acid biosynthetic process | biological_process | BRCA1 |
| negative regulation of feeding behavior | biological_process | ESR2, UCN, CRHR2, RETN |
| negative regulation of female gonad development | biological_process | WT1, NR5A1 |
| negative regulation of ferrous iron export | biological_process | HAMP |
| negative regulation of fibrinolysis | biological_process | USF1, SERPINE1, THBS1, CPB2 |
| negative regulation of fibroblast apoptotic process | biological_process | PIK3CA, GAS6 |
| negative regulation of fibroblast growth factor receptor signaling pathway | biological_process | WNT5A, SPRY2, THBS1, WNT4 |
| negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | biological_process | GATA3 |
| negative regulation of fibroblast migration | biological_process | FGF2, BRAF |
| negative regulation of fibroblast proliferation | biological_process | AGTR2, GSTP1, TP53, MYC, LTA, BAX |
| negative regulation of focal adhesion assembly | biological_process | SRC, MMP14, THBS1, PTEN |
| negative regulation of follicle-stimulating hormone secretion | biological_process | INHBA, INHA, CRHR2, UCN2 |
| negative regulation of forebrain neuron differentiation | biological_process | PTGER3, HES5 |
| negative regulation of G-protein coupled receptor protein signaling pathway | biological_process | CCL5, CXCL8 |
| negative regulation of G1/S transition of mitotic cell cycle | biological_process | BCL2, CDKN1A, RB1, PTEN, EZH2 |
| negative regulation of gap junction assembly | biological_process | ACE |
| negative regulation of gastric acid secretion | biological_process | OXTR, PTGER3, UCN |
| negative regulation of gastrin-induced gastric acid secretion | biological_process | PTGER3 |
| negative regulation of gene expression | biological_process | XDH, FGFR1, GATA3, NOS2, BMP4, GJA1, CD36, MIF, AKT1, CTNNB1, CCNB1, CCL3, SERPINF1, NME1, ID1, CCR1, CDKN1A, ESR1, INSR, IFNG, CRYAB, TGFB1, TNF, TERT, LGALS9, FYN, RB1, PRDM1, PGR, IL1B, CRH, CDC42, TGFB2, PARK7, SMAD2, AIF1, HDAC1, EZH2, SIRT1, ID2, PTPN22, GPER1, NR0B2, UCN, WNT4, DLL4, CRHR2, OLFM1, UCN2 |
| negative regulation of gene expression, epigenetic | biological_process | DNMT1, DNMT3A, EZH2, DNMT3B, HIST2H3A |
| negative regulation of gene silencing by miRNA | biological_process | TGFB1, POU5F1 |
| negative regulation of glial cell apoptotic process | biological_process | CCL2 |
| negative regulation of glial cell proliferation | biological_process | NOTCH1, PTN |
| negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation | biological_process | GATA3 |
| negative regulation of glomerular filtration | biological_process | F2R |
| negative regulation of glomerular mesangial cell proliferation | biological_process | BMP4 |
| negative regulation of glomerulus development | biological_process | BMP4 |
| negative regulation of glucagon secretion | biological_process | LEP, CRH |
| negative regulation of glucocorticoid receptor signaling pathway | biological_process | CLOCK |
| negative regulation of gluconeogenesis | biological_process | LEPR, IL6, ADIPOQ, MST1 |
| negative regulation of glucose import | biological_process | LEP, ESR1, TNF |
| negative regulation of glucose transport | biological_process | PRKCB, IL1B |
| negative regulation of glutamate secretion | biological_process | IL1B |
| negative regulation of glutamine transport | biological_process | LEP |
| negative regulation of glycogen (starch) synthase activity | biological_process | GSK3B |
| negative regulation of glycogen biosynthetic process | biological_process | GSK3B |
| negative regulation of glycolytic process | biological_process | STAT3, PPARA |
| negative regulation of glycoprotein metabolic process | biological_process | PTX3, APCS |
| negative regulation of granulocyte differentiation | biological_process | ADIPOQ |
| negative regulation of growth | biological_process | IGFBP5, HIF1A |
| negative regulation of growth of symbiont in host | biological_process | CD36, IL10, IL12B, MBL2, IFNG, TNF, LTA, MPO, CTSG |
| negative regulation of growth of symbiont involved in interaction with host | biological_process | IFNG |
| negative regulation of GTPase activity | biological_process | SPRY2, KLRK1 |
| negative regulation of heart contraction | biological_process | IL2 |
| negative regulation of heart rate | biological_process | AGTR2 |
| negative regulation of helicase activity | biological_process | TP53, SIRT1 |
| negative regulation of hematopoietic stem cell differentiation | biological_process | NFE2L2 |
| negative regulation of hepatocyte proliferation | biological_process | CPB2 |
| negative regulation of heterotypic cell-cell adhesion | biological_process | IL1RN, APOA1, ADIPOQ |
| negative regulation of histone acetylation | biological_process | BRCA1, SET, FOXP3, TWIST1 |
| negative regulation of histone deacetylation | biological_process | FOXP3, UCN |
| negative regulation of histone H3-K14 acetylation | biological_process | SIRT1 |
| negative regulation of histone H3-K4 methylation | biological_process | BRCA1 |
| negative regulation of histone H3-K9 methylation | biological_process | DNMT1, BRCA1, DNMT3B |
| negative regulation of histone H4-K16 acetylation | biological_process | SIRT1 |
| negative regulation of histone phosphorylation | biological_process | TWIST1 |
| negative regulation of hormone secretion | biological_process | LIF, IL11, IL6, EDN1, ADIPOQ, UCN |
| negative regulation of hyaluronan biosynthetic process | biological_process | TGFB1 |
| negative regulation of hydrogen peroxide biosynthetic process | biological_process | STAT3 |
| negative regulation of hydrogen peroxide catabolic process | biological_process | HP |
| negative regulation of hydrogen peroxide metabolic process | biological_process | PTGER4, MMP3 |
| negative regulation of hydrogen peroxide-induced cell death | biological_process | TXN, PSAP, PARK7, NFE2L2 |
| negative regulation of hydrogen peroxide-induced neuron death | biological_process | PARK7 |
| negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway | biological_process | PARK7 |
| negative regulation of hydrogen peroxide-mediated programmed cell death | biological_process | MET, HGF |
| negative regulation of hydrolase activity | biological_process | LEPR, NOS3, APOA1 |
| negative regulation of I-kappaB kinase/NF-kappaB signaling | biological_process | GSTP1, ESR1, CCDC22, ADIPOQ, SIRT1, IL1RL1 |
| negative regulation of icosanoid secretion | biological_process | AGTR2 |
| negative regulation of immature T cell proliferation in thymus | biological_process | BMP4, ERBB2, CDKN2A, IHH |
| negative regulation of immune response | biological_process | HLA-G, TGFB1, IL2RA, TGFB2, FOXP3 |
| negative regulation of immunoglobulin secretion | biological_process | IL33 |
| negative regulation of immunological synapse formation | biological_process | LGALS3 |
| negative regulation of inflammatory response | biological_process | GATA3, TNFRSF1A, IL10, PTGER4, SERPINF1, NFKB1, TNFRSF1B, HGF, SAA1, APOA1, APOE, SOCS3, ADA, KRT1, IL2RA, SMAD3, TYRO3, TEK, ADIPOQ, GHRL, PPARA, FOXP3, GPER1, IL2 |
| negative regulation of inflammatory response to antigenic stimulus | biological_process | IL12B, GPX1 |
| negative regulation of innate immune response | biological_process | DRD2, TYRO3 |
| negative regulation of inner ear receptor cell differentiation | biological_process | HES5 |
| negative regulation of insulin receptor signaling pathway | biological_process | PRKCB, AHSG, SOCS3, MSTN, IL1B, RELA |
| negative regulation of insulin secretion | biological_process | DRD2, PTGER3, PSMD9, GHRL |
| negative regulation of insulin secretion involved in cellular response to glucose stimulus | biological_process | CRHR2 |
| negative regulation of insulin-like growth factor receptor signaling pathway | biological_process | IGFBP5 |
| negative regulation of integrin activation | biological_process | PTGER4 |
| negative regulation of integrin biosynthetic process | biological_process | AR |
| negative regulation of integrin-mediated signaling pathway | biological_process | CTNNA1 |
| negative regulation of interferon-alpha biosynthetic process | biological_process | IL10 |
| negative regulation of interferon-beta secretion | biological_process | LILRB1 |
| negative regulation of interferon-gamma biosynthetic process | biological_process | INHBA, INHA, FOXP3, LILRB1 |
| negative regulation of interferon-gamma production | biological_process | GATA3, HMGB1, IL10, AXL, HLA-DRB1, LGALS9, TLR4, IL33, C1QBP, GAS6, FOXP3, IL1RL1, IL20RB, LILRB1 |
| negative regulation of interferon-gamma-mediated signaling pathway | biological_process | PPARG |
| negative regulation of interleukin-1 alpha secretion | biological_process | PTGER4 |
| negative regulation of interleukin-1 beta production | biological_process | GSTP1, GHRL, ERRFI1 |
| negative regulation of interleukin-1 beta secretion | biological_process | APOA1 |
| negative regulation of interleukin-1 production | biological_process | IL10 |
| negative regulation of interleukin-1 secretion | biological_process | GAS6 |
| negative regulation of interleukin-1-mediated signaling pathway | biological_process | IL1RN |
| negative regulation of interleukin-10 production | biological_process | IL12B, IDO1, FOXP3, AGER, IL23A |
| negative regulation of interleukin-10 secretion | biological_process | TNFRSF21, LILRB1 |
| negative regulation of interleukin-12 biosynthetic process | biological_process | NFKB1 |
| negative regulation of interleukin-12 production | biological_process | IL10, THBS1, C1QBP |
| negative regulation of interleukin-12 secretion | biological_process | LILRB1 |
| negative regulation of interleukin-13 secretion | biological_process | TNFRSF21 |
| negative regulation of interleukin-17 production | biological_process | IL12B, IL12A, IFNG, TGFB1, TLR4, FOXP3 |
| negative regulation of interleukin-18 production | biological_process | IL10 |
| negative regulation of interleukin-2 biosynthetic process | biological_process | FOXP3 |
| negative regulation of interleukin-2 production | biological_process | GATA3, FOXP3, IL20RB |
| negative regulation of interleukin-23 production | biological_process | TLR4, RAC1 |
| negative regulation of interleukin-4 production | biological_process | FOXP3, CD83 |
| negative regulation of interleukin-5 production | biological_process | FOXP3 |
| negative regulation of interleukin-5 secretion | biological_process | TNFRSF21 |
| negative regulation of interleukin-6 biosynthetic process | biological_process | GHRL |
| negative regulation of interleukin-6 production | biological_process | IL10, HGF, TNF, TLR4, GAS6, TLR9, FOXP3 |
| negative regulation of interleukin-6 secretion | biological_process | GAS6, PTPN22 |
| negative regulation of interleukin-6-mediated signaling pathway | biological_process | IL6ST |
| negative regulation of interleukin-8 production | biological_process | IL10, IL6R, TLR9 |
| negative regulation of interleukin-8 secretion | biological_process | ANXA4, ANXA1, PTPN22 |
| negative regulation of intestinal absorption | biological_process | HAMP |
| negative regulation of intracellular estrogen receptor signaling pathway | biological_process | BRCA1, ZNF366 |
| negative regulation of intracellular protein transport | biological_process | ADIPOQ |
| negative regulation of intracellular transport | biological_process | CRYAB |
| negative regulation of intrinsic apoptotic signaling pathway | biological_process | BCL2, SRC, MMP9, BCL2L1, PLAUR, MCL1 |
| negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | biological_process | CLU, CXCL12, SNAI1, BCL2L1 |
| negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological_process | MIF, MUC1, CD44, CD74, SIRT1 |
| negative regulation of iodide transmembrane transport | biological_process | MTOR |
| negative regulation of ion transmembrane transporter activity | biological_process | HAMP |
| negative regulation of iron channel activity | biological_process | HAMP |
| negative regulation of isotype switching to IgE isotypes | biological_process | BCL6, FOXP3 |
| negative regulation of JAK-STAT cascade | biological_process | BGN, SOCS3, DCN |
| negative regulation of JNK cascade | biological_process | AKT1, F2RL1 |
| negative regulation of JUN kinase activity | biological_process | GSTP1, PTPN22 |
| negative regulation of keratinocyte differentiation | biological_process | TP63 |
| negative regulation of keratinocyte proliferation | biological_process | VDR, KLF9 |
| negative regulation of kinase activity | biological_process | CDKN1B, MSTN, IRS2 |
| negative regulation of leukocyte activation | biological_process | GPER1 |
| negative regulation of leukocyte apoptotic process | biological_process | CXCL12, CCL21, CCL19, CCR7 |
| negative regulation of leukocyte cell-cell adhesion | biological_process | PPARA |
| negative regulation of leukocyte chemotaxis | biological_process | GREM1 |
| negative regulation of leukocyte migration | biological_process | HMOX1, IL33, ADA |
| negative regulation of leukocyte proliferation | biological_process | GSTP1 |
| negative regulation of leukocyte tethering or rolling | biological_process | CXCL12, CCL25, CCL21 |
| negative regulation of lipase activity | biological_process | APOA1, APOA2 |
| negative regulation of lipid biosynthetic process | biological_process | APOE, GPER1 |
| negative regulation of lipid catabolic process | biological_process | APOA2, TNF, IL1B |
| negative regulation of lipid metabolic process | biological_process | IL1B |
| negative regulation of lipid storage | biological_process | LEP, ITGB3, ITGAV, TNF, CRP, IL6 |
| negative regulation of lipid transport | biological_process | ITGB3, ITGAV |
| negative regulation of lipid transport across blood brain barrier | biological_process | APOE |
| negative regulation of lipopolysaccharide-mediated signaling pathway | biological_process | LTF, PRDM1 |
| negative regulation of lipoprotein metabolic process | biological_process | ITGB3, ITGAV |
| negative regulation of locomotion | biological_process | GHRL |
| negative regulation of low-density lipoprotein particle receptor biosynthetic process | biological_process | ITGB3, ITGAV, ADIPOQ |
| negative regulation of low-density lipoprotein particle receptor catabolic process | biological_process | ANXA2 |
| negative regulation of lung ciliated cell differentiation | biological_process | IL13 |
| negative regulation of luteinizing hormone secretion | biological_process | TACR2, CRH, CRHR2, UCN2 |
| negative regulation of lymphocyte activation | biological_process | AXL, TYRO3 |
| negative regulation of lymphocyte proliferation | biological_process | IL2RA, FOXP3, IL2 |
| negative regulation of macroautophagy | biological_process | MTOR |
| negative regulation of macrophage activation | biological_process | IL4 |
| negative regulation of macrophage apoptotic process | biological_process | CCL5, NOD2 |
| negative regulation of macrophage chemotaxis | biological_process | CYP19A1, C5 |
| negative regulation of macrophage cytokine production | biological_process | TGFB1, TGFB2 |
| negative regulation of macrophage derived foam cell differentiation | biological_process | CETP, PPARG, ITGB3, ITGAV, CRP, ADIPOQ, PPARA |
| negative regulation of macrophage differentiation | biological_process | INHBA, GATA2, INHA, ADIPOQ |
| negative regulation of male germ cell proliferation | biological_process | PTGDS |
| negative regulation of male gonad development | biological_process | WNT4 |
| negative regulation of mammary gland epithelial cell proliferation | biological_process | GATA3, BRCA2 |
| negative regulation of MAP kinase activity | biological_process | GSK3B, BMP4, UCHL1, GSTP1, APOE, SPRY2, IL1B, ADIPOQ |
| negative regulation of MAPK cascade | biological_process | GSTP1, PSMD10 |
| negative regulation of mast cell apoptotic process | biological_process | KITLG, FCER1G |
| negative regulation of mast cell cytokine production | biological_process | BCL6, HMOX1 |
| negative regulation of mast cell degranulation | biological_process | HMOX1, LGALS9 |
| negative regulation of mature B cell apoptotic process | biological_process | MIF, ADA, CD74 |
| negative regulation of MDA-5 signaling pathway | biological_process | C1QBP |
| negative regulation of meiotic nuclear division | biological_process | LIF |
| negative regulation of melanin biosynthetic process | biological_process | WNT5A |
| negative regulation of membrane potential | biological_process | PTN |
| negative regulation of membrane protein ectodomain proteolysis | biological_process | IL10, TIMP2, TIMP3, TIMP1, TIMP4 |
| negative regulation of mesenchymal cell apoptotic process | biological_process | HIF1A |
| negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis | biological_process | HNF1B |
| negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis | biological_process | PAX2 |
| negative regulation of mesenchymal cell apoptotic process involved in metanephros development | biological_process | HNF1B, PAX2 |
| negative regulation of mesenchymal cell proliferation | biological_process | WNT5A, PTN |
| negative regulation of mesenchymal cell proliferation involved in ureter development | biological_process | BMP4 |
| negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological_process | CTNNB1 |
| negative regulation of mesoderm development | biological_process | TP63 |
| negative regulation of mesodermal cell fate specification | biological_process | DKK1 |
| negative regulation of metabolic process | biological_process | LEP |
| negative regulation of metalloendopeptidase activity | biological_process | TIMP3 |
| negative regulation of metanephric comma-shaped body morphogenesis | biological_process | BMP4 |
| negative regulation of metanephric glomerular mesangial cell proliferation | biological_process | WT1 |
| negative regulation of metanephric mesenchymal cell migration | biological_process | ADIPOQ |
| negative regulation of metanephric S-shaped body morphogenesis | biological_process | BMP4 |
| negative regulation of methylation-dependent chromatin silencing | biological_process | TET1 |
| negative regulation of MHC class II biosynthetic process | biological_process | IL10, HDAC2 |
| negative regulation of microtubule polymerization | biological_process | STMN1, SGK1, FKBP4 |
| negative regulation of microtubule polymerization or depolymerization | biological_process | FKBP4 |
| negative regulation of mitochondrial depolarization | biological_process | BCL2, SRC |
| negative regulation of mitotic cell cycle | biological_process | BCL2, CDKN1B, TIMP2, TGFB1, RB1, SMAD3 |
| negative regulation of mitotic cell cycle, embryonic | biological_process | CTNNB1 |
| negative regulation of mitotic nuclear division | biological_process | BMP4 |
| negative regulation of mitotic recombination | biological_process | MLH1 |
| negative regulation of molecular function | biological_process | TWIST1 |
| negative regulation of monocyte chemotactic protein-1 production | biological_process | GSTP1 |
| negative regulation of monocyte chemotaxis | biological_process | GREM1 |
| negative regulation of monocyte differentiation | biological_process | MYC, APCS |
| negative regulation of monocyte extravasation | biological_process | PLCB1 |
| negative regulation of mononuclear cell proliferation | biological_process | LILRB1 |
| negative regulation of mRNA splicing, via spliceosome | biological_process | C1QBP |
| negative regulation of mucus secretion | biological_process | ADA |
| negative regulation of muscle atrophy | biological_process | MTOR |
| negative regulation of muscle cell apoptotic process | biological_process | HMOX1, LIFR |
| negative regulation of muscle hyperplasia | biological_process | NOS3 |
| negative regulation of muscle hypertrophy | biological_process | MSTN |
| negative regulation of muscle organ development | biological_process | IL6 |
| negative regulation of muscle tissue development | biological_process | IGFBP5 |
| negative regulation of MyD88-independent toll-like receptor signaling pathway | biological_process | TLR4, TLR3 |
| negative regulation of myelination | biological_process | IFNG, TNFRSF21, PTEN |
| negative regulation of myeloid cell apoptotic process | biological_process | BCL2, MIF |
| negative regulation of myeloid cell differentiation | biological_process | GATA2, MEIS1 |
| negative regulation of myeloid dendritic cell activation | biological_process | IL10 |
| negative regulation of myeloid leukocyte differentiation | biological_process | NME1 |
| negative regulation of myoblast differentiation | biological_process | BMP4, NOTCH1, TGFB1, TNF, CXCL10, MSTN, CXCL14, IL18, CCL17 |
| negative regulation of myoblast fusion | biological_process | CXCL10 |
| negative regulation of myoblast proliferation | biological_process | MSTN |
| negative regulation of myosin-light-chain-phosphatase activity | biological_process | TNF |
| negative regulation of myotube differentiation | biological_process | NOTCH1, HDAC1 |
| negative regulation of NAD(P)H oxidase activity | biological_process | IL13 |
| negative regulation of natural killer cell activation | biological_process | MICA |
| negative regulation of natural killer cell chemotaxis | biological_process | CCL2, KLRK1 |
| negative regulation of natural killer cell mediated cytotoxicity | biological_process | LGALS9, IGF2, MICA, LILRB1 |
| negative regulation of necrotic cell death | biological_process | UCN |
| negative regulation of neural precursor cell proliferation | biological_process | GATA2, CCR2, IL1B, ID2 |
| negative regulation of neuroblast proliferation | biological_process | CTNNA1, TGFB1 |
| negative regulation of neurogenesis | biological_process | NOTCH1, WNT7A, IL1B |
| negative regulation of neuromuscular junction development | biological_process | PTN |
| negative regulation of neuron apoptotic process | biological_process | GCLC, MSH2, BCL2, F2R, ERBB3, BRAF, AXL, CNTF, HMOX1, CCL2, MDK, PIK3CA, BDNF, NTF4, STAR, JUN, SOD1, NGF, APOE, FYN, NRP1, KRAS, BCL2L1, PARK7, NTRK2, HIF1A, TYRO3, BAX, SET, ADAM8, ANGPT1 |
| negative regulation of neuron death | biological_process | STAT3, CCL5, AKT1, CTNNB1, SERPINF1, MDK, IL13, ESR1, IGF1, APOE, IL6, PARK7, ESR2, PPARA, SIRT1, UCN |
| negative regulation of neuron differentiation | biological_process | SLC6A4, NOTCH1, SOX2, ITGB1, MEIS1, IL1B, HES5, ID2, JAG1 |
| negative regulation of neuron maturation | biological_process | GSK3B |
| negative regulation of neuron migration | biological_process | GSK3B, STAT3, NRG1 |
| negative regulation of neuron projection development | biological_process | GSK3B, VIM, LGALS1, HDAC2, FKBP4 |
| negative regulation of neurotrophin TRK receptor signaling pathway | biological_process | AGTR2, SPRY2 |
| negative regulation of NF-kappaB transcription factor activity | biological_process | CDKN2A, ANXA4, PSMD10, CAT, TLR9, FOXP3, SIRT1, CYP1B1 |
| negative regulation of NFAT protein import into nucleus | biological_process | GSK3B, MTOR |
| negative regulation of NIK/NF-kappaB signaling | biological_process | RASSF2, RELA |
| negative regulation of nitric oxide biosynthetic process | biological_process | IL10, OPRM1, IL4 |
| negative regulation of nitric oxide mediated signal transduction | biological_process | THBS1, SPINK1 |
| negative regulation of nitric-oxide synthase activity | biological_process | GSK3B, ENG |
| negative regulation of nitric-oxide synthase biosynthetic process | biological_process | PTGER4, GSTP1, EDN1 |
| negative regulation of norepinephrine secretion | biological_process | AGTR2, PTGS1, PTGER3, CRH, CRHR2 |
| negative regulation of Notch signaling pathway | biological_process | BCL6, GATA2, MMP14, HEY1, DLL4 |
| negative regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological_process | TOB1 |
| negative regulation of nucleic acid-templated transcription | biological_process | YAP1, APEX1, TOB1, NANOG |
| negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_process | PTPN22 |
| negative regulation of odontogenesis of dentin-containing tooth | biological_process | TNFRSF11B |
| negative regulation of oligodendrocyte apoptotic process | biological_process | GAS6 |
| negative regulation of oligodendrocyte differentiation | biological_process | BMP4, CTNNB1, NOTCH1, HES5, ID2 |
| negative regulation of oocyte development | biological_process | IGF1 |
| negative regulation of organ growth | biological_process | SLC6A4, PTEN, PTK2 |
| negative regulation of ossification | biological_process | BCL2, NOTCH1, TGFB1, HIF1A |
| negative regulation of osteoblast differentiation | biological_process | FGFR1, TOB1, NOTCH1, ID1, IGFBP5, TNF, SMAD3, ID2, TWIST1 |
| negative regulation of osteoblast proliferation | biological_process | BCL2, GREM1, SMAD3, AGER |
| negative regulation of osteoclast development | biological_process | LTF, LILRB1 |
| negative regulation of osteoclast differentiation | biological_process | PIK3R1, CTNNB1, CCL3, FSTL3, TLR4, TLR3, IL4 |
| negative regulation of osteoclast proliferation | biological_process | GREM1 |
| negative regulation of ovarian follicle development | biological_process | AMH |
| negative regulation of oxidative phosphorylation uncoupler activity | biological_process | TWIST1 |
| negative regulation of oxidative stress-induced cell death | biological_process | PARK7 |
| negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological_process | AKT1, HSPB1, GPX1, NFE2L2, SIRT1 |
| negative regulation of oxidative stress-induced neuron death | biological_process | PARK7 |
| negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological_process | PARK7, HIF1A |
| negative regulation of oxidoreductase activity | biological_process | HP |
| negative regulation of p38MAPK cascade | biological_process | PTPN22 |
| negative regulation of pancreatic stellate cell proliferation | biological_process | PPARG |
| negative regulation of pathway-restricted SMAD protein phosphorylation | biological_process | ENG, GREM1, SMAD7, DKK1 |
| negative regulation of penile erection | biological_process | ADA |
| negative regulation of peptidase activity | biological_process | TIMP2, TIMP3, A2M, SERPINA1, NGF, TIMP1, BIRC5, SLPI, SERPINE1, SPINK1, SERPINB2, WFDC2, TIMP4 |
| negative regulation of peptide secretion | biological_process | PTGER4, CD74 |
| negative regulation of peptidyl-lysine acetylation | biological_process | HDAC2, SIRT1 |
| negative regulation of peptidyl-serine phosphorylation | biological_process | RASSF2, HGF, SMAD7, DKK1, BAX |
| negative regulation of peptidyl-threonine phosphorylation | biological_process | SMAD7, SPRY2 |
| negative regulation of peptidyl-tyrosine phosphorylation | biological_process | SPINK1, ERRFI1 |
| negative regulation of peroxisome proliferator activated receptor signaling pathway | biological_process | TWIST1 |
| negative regulation of phagocytosis | biological_process | TGFB1, PTEN, ADIPOQ |
| negative regulation of phosphatidylinositol 3-kinase signaling | biological_process | PTEN, TWIST1 |
| negative regulation of phosphatidylinositol biosynthetic process | biological_process | PDGFA |
| negative regulation of phospholipase A2 activity | biological_process | ANXA1 |
| negative regulation of phospholipid efflux | biological_process | APOE |
| negative regulation of phosphorylation | biological_process | INHBA, BMP4, CDKN1B, CDKN1A, CDKN2A, INHA, AHSG, SIRT1 |
| negative regulation of photoreceptor cell differentiation | biological_process | NOTCH1, CNTF |
| negative regulation of plasma lipoprotein particle oxidation | biological_process | PON1 |
| negative regulation of plasma membrane long-chain fatty acid transport | biological_process | AKT1, THBS1, IRS2 |
| negative regulation of plasminogen activation | biological_process | SERPINE1, THBS1, CPB2 |
| negative regulation of platelet activation | biological_process | PDGFRA, NOS3, APOE, PDGFA |
| negative regulation of platelet aggregation | biological_process | PTGER3 |
| negative regulation of platelet-derived growth factor receptor signaling pathway | biological_process | ADIPOQ |
| negative regulation of platelet-derived growth factor receptor-alpha signaling pathway | biological_process | ADIPOQ |
| negative regulation of positive chemotaxis | biological_process | ANGPT2 |
| negative regulation of postsynaptic membrane organization | biological_process | APOE |
| negative regulation of potassium ion transmembrane transport | biological_process | PTGER3 |
| negative regulation of potassium ion transport | biological_process | NOS3 |
| negative regulation of presynaptic membrane organization | biological_process | APOE |
| negative regulation of pri-miRNA transcription from RNA polymerase II promoter | biological_process | PPARA |
| negative regulation of pro-B cell differentiation | biological_process | NOTCH1, HES5 |
| negative regulation of production of miRNAs involved in gene silencing by miRNA | biological_process | ESR1, TGFB1 |
| negative regulation of production of siRNA involved in RNA interference | biological_process | TERT |
| negative regulation of programmed cell death | biological_process | KIT, PAX2 |
| negative regulation of prolactin secretion | biological_process | ANXA5 |
| negative regulation of prostaglandin biosynthetic process | biological_process | SIRT1 |
| negative regulation of prostatic bud formation | biological_process | BMP4, WNT5A |
| negative regulation of proteasomal ubiquitin-dependent protein catabolic process | biological_process | PARK7, FHIT |
| negative regulation of protein acetylation | biological_process | PARK7, SIRT1 |
| negative regulation of protein autophosphorylation | biological_process | ENG, JUN, ADIPOQ, ERRFI1 |
| negative regulation of protein binding | biological_process | GSK3B, ID1, AURKA, SLPI, DKK1, PARK7, BAX, PPARA |
| negative regulation of protein catabolic process | biological_process | NOS2, EGFR, FYN, RELA, NRG1, PARK7 |
| negative regulation of protein complex assembly | biological_process | GSK3B, CDC42, EIF4EBP1 |
| negative regulation of protein complex disassembly | biological_process | TNF |
| negative regulation of protein export from nucleus | biological_process | TXN, PARK7 |
| negative regulation of protein homodimerization activity | biological_process | ID1 |
| negative regulation of protein homooligomerization | biological_process | SRC, CLU, CLDN7 |
| negative regulation of protein import into nucleus | biological_process | ANGPT1 |
| negative regulation of protein import into nucleus, translocation | biological_process | GAS6 |
| negative regulation of protein K48-linked deubiquitination | biological_process | PARK7 |
| negative regulation of protein kinase activity | biological_process | BGN, AKT1, GSTP1, HSPB1, RB1, SOCS3, IL6, PARK7, CDKN2A, CEP85, DCN |
| negative regulation of protein kinase activity by protein phosphorylation | biological_process | AKT1 |
| negative regulation of protein kinase B signaling | biological_process | XDH, DRD2, PDCD6, MSTN, PTEN, SIRT1, GPER1 |
| negative regulation of protein localization to cell surface | biological_process | ASTN2 |
| negative regulation of protein localization to nucleus | biological_process | GSK3B |
| negative regulation of protein localization to plasma membrane | biological_process | TGFB1 |
| negative regulation of protein oligomerization | biological_process | HIST3H3 |
| negative regulation of protein phosphorylation | biological_process | XDH, FBLN1, IGFBP3, CCNB1, MTOR, INSR, TGFB1, PTEN, PARK7, AGER, IL2, ANGPT1 |
| negative regulation of protein secretion | biological_process | DRD2, ANXA1 |
| negative regulation of protein serine/threonine kinase activity | biological_process | HSPB1 |
| negative regulation of protein sumoylation | biological_process | CTNNB1, PARK7, PIAS3 |
| negative regulation of protein ubiquitination | biological_process | GCLC, MTOR, FYN, SMAD7, PARK7 |
| negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological_process | WNT1, CDKN2A |
| negative regulation of proteolysis | biological_process | AKT1, TIMP2, TIMP3, PLAT |
| negative regulation of proteolysis involved in cellular protein catabolic process | biological_process | CDKN2A |
| negative regulation of Ras protein signal transduction | biological_process | TIMP2, SPRY2, TGFB2 |
| negative regulation of reactive oxygen species metabolic process | biological_process | BCL2, BRCA1, CRYAB, HIF1A, ESR2, PAX2 |
| negative regulation of receptor binding | biological_process | ANXA2, ADIPOQ |
| negative regulation of receptor biosynthetic process | biological_process | PPARG, PPARA |
| negative regulation of receptor internalization | biological_process | ANXA2 |
| negative regulation of receptor-mediated endocytosis | biological_process | RAC1 |
| negative regulation of reciprocal meiotic recombination | biological_process | MSH2 |
| negative regulation of regulatory T cell differentiation | biological_process | CTLA4 |
| negative regulation of release of cytochrome c from mitochondria | biological_process | AKT1, HGF, IGF1, PSMD10, GPX1, BCL2L1 |
| negative regulation of release of sequestered calcium ion into cytosol | biological_process | TGFB1 |
| negative regulation of renal albumin absorption | biological_process | GAS6 |
| negative regulation of renal phosphate excretion | biological_process | STC1 |
| negative regulation of renal sodium excretion | biological_process | COMT |
| negative regulation of renin secretion into blood stream | biological_process | F2R |
| negative regulation of response to cytokine stimulus | biological_process | APOA1 |
| negative regulation of retinal cell programmed cell death | biological_process | BCL2 |
| negative regulation of retinoic acid biosynthetic process | biological_process | AKR1C3 |
| negative regulation of retinoic acid receptor signaling pathway | biological_process | CYP26A1, EZH2 |
| negative regulation of Rho protein signal transduction | biological_process | BCL6, ITGA3, ITGB1 |
| negative regulation of ribosome biogenesis | biological_process | PTEN |
| negative regulation of RIG-I signaling pathway | biological_process | C1QBP |
| negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological_process | ID1 |
| negative regulation of RNA polymerase II transcriptional preinitiation complex assembly | biological_process | HMGB1 |
| negative regulation of satellite cell differentiation | biological_process | MSTN |
| negative regulation of Schwann cell proliferation | biological_process | DICER1 |
| negative regulation of secretion | biological_process | ERBB3, EGF, NRG1 |
| negative regulation of sequence-specific DNA binding transcription factor activity | biological_process | ID1, HMOX1, ESR1, SMAD7, RB1, HDAC2, GAS6, FOXP3, EZH2, SIRT1, ID2, TWIST1, NR0B2, SFRP4 |
| negative regulation of sequestering of triglyceride | biological_process | PPARG, PPARA |
| negative regulation of serine-type endopeptidase activity | biological_process | SPINK1 |
| negative regulation of serotonin secretion | biological_process | LILRB1 |
| negative regulation of signal transduction | biological_process | GSK3B, IGFBP3, ERBB3, SOCS3, IHH |
| negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological_process | HMGA2 |
| negative regulation of single-species biofilm formation in or on host organism | biological_process | LTF |
| negative regulation of skeletal muscle hypertrophy | biological_process | IGFBP5 |
| negative regulation of skeletal muscle satellite cell proliferation | biological_process | MSTN |
| negative regulation of skeletal muscle tissue development | biological_process | TGFB1, DKK1, TWIST1 |
| negative regulation of skeletal muscle tissue growth | biological_process | MSTN |
| negative regulation of small intestine smooth muscle contraction | biological_process | PTGER4 |
| negative regulation of smooth muscle cell apoptotic process | biological_process | GSK3B, IGF1, EDN1 |
| negative regulation of smooth muscle cell chemotaxis | biological_process | AIF1 |
| negative regulation of smooth muscle cell migration | biological_process | IGFBP3, APEX1, IGFBP5, SERPINE1, ADIPOQ |
| negative regulation of smooth muscle cell proliferation | biological_process | PPARG, IGFBP3, IL12B, IGFBP5, HMOX1, IL15, COMT, IL12A, ESR1, ANG, IFNG, ADIPOQ, AIF1, ESR2 |
| negative regulation of smooth muscle cell-matrix adhesion | biological_process | SERPINE1 |
| negative regulation of smooth muscle contraction | biological_process | PTGS2 |
| negative regulation of smoothened signaling pathway | biological_process | RB1 |
| negative regulation of sodium-dependent phosphate transport | biological_process | SFRP4 |
| negative regulation of stem cell differentiation | biological_process | YAP1, NOTCH1, HES5, JAG1 |
| negative regulation of stem cell proliferation | biological_process | FBLN1 |
| negative regulation of steroid biosynthetic process | biological_process | WNT4 |
| negative regulation of stress-activated MAPK cascade | biological_process | GSTP1, MYC, FOXO1 |
| negative regulation of striated muscle cell differentiation | biological_process | EZH2 |
| negative regulation of striated muscle tissue development | biological_process | BMP4, SOX15, TWIST1 |
| negative regulation of substrate adhesion-dependent cell spreading | biological_process | FBLN1, ACTN4, POSTN |
| negative regulation of synapse assembly | biological_process | WNT5A, DKK1, PTK2 |
| negative regulation of synaptic transmission | biological_process | BCHE, PCDH17, ADIPOQ |
| negative regulation of synaptic transmission, dopaminergic | biological_process | SLC6A4, PTGS2 |
| negative regulation of synaptic transmission, glutamatergic | biological_process | DRD2 |
| negative regulation of synaptic vesicle clustering | biological_process | PTEN |
| negative regulation of synaptic vesicle exocytosis | biological_process | BRAF |
| negative regulation of T cell activation | biological_process | TGFB1, IL4, PTPN22 |
| negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological_process | LGALS3, LILRB1 |
| negative regulation of T cell apoptotic process | biological_process | CCL5, IDO1 |
| negative regulation of T cell cytokine production | biological_process | FOXP3 |
| negative regulation of T cell differentiation | biological_process | CD74 |
| negative regulation of T cell differentiation in thymus | biological_process | BMP4, IHH |
| negative regulation of T cell mediated cytotoxicity | biological_process | LILRB1 |
| negative regulation of T cell proliferation | biological_process | IL10, HLA-DRB1, IDO1, HLA-G, TGFB1, TNFRSF21, IL2RA, FOXP3, IL20RB, LILRB1 |
| negative regulation of T cell receptor signaling pathway | biological_process | LGALS3, PTPN22 |
| negative regulation of T-helper 1 type immune response | biological_process | IL33, IL1RL1 |
| negative regulation of T-helper 17 cell differentiation | biological_process | IL4, FOXP3 |
| negative regulation of T-helper 2 cell differentiation | biological_process | BCL6, ANXA1 |
| negative regulation of telomerase activity | biological_process | SRC, PPARG, TP53 |
| negative regulation of telomere capping | biological_process | ATM |
| negative regulation of telomere maintenance via telomerase | biological_process | SRC |
| negative regulation of testicular blood vessel morphogenesis | biological_process | WNT4 |
| negative regulation of testosterone biosynthetic process | biological_process | WNT4 |
| negative regulation of thymocyte apoptotic process | biological_process | BMP4, ADA, HIF1A |
| negative regulation of toll-like receptor 3 signaling pathway | biological_process | F2RL1 |
| negative regulation of toll-like receptor signaling pathway | biological_process | TYRO3, TLR9 |
| negative regulation of TOR signaling | biological_process | PDCD6, HIF1A, SIRT1 |
| negative regulation of TORC1 signaling | biological_process | ATM |
| negative regulation of TRAIL-activated apoptotic signaling pathway | biological_process | PARK7 |
| negative regulation of transcription by competitive promoter binding | biological_process | MUC1, SMAD7 |
| negative regulation of transcription by transcription factor localization | biological_process | ID1 |
| negative regulation of transcription elongation from RNA polymerase II promoter | biological_process | EZH2 |
| negative regulation of transcription factor import into nucleus | biological_process | CD36 |
| negative regulation of transcription from RNA polymerase II promoter | biological_process | FGFR1, EGR1, TXN, GATA3, CCND1, VEGFA, BCL6, STAT3, NR2F2, BMP4, DNMT1, HMGA2, PPARG, FGFR2, HMGB1, CD36, LEP, CTNNB1, ATF2, NFKB1, NOTCH1, ID1, FASLG, VDR, ENG, FST, GATA2, STAT6, WT1, HNF1B, EFNA1, BMP6, SOX2, ZEB1, ESR1, IFNG, TGFB1, TP53, SUV39H1, TNF, MYC, ENO1, SMAD7, RB1, ARID1A, SOX15, KLF11, SNAI1, DKK1, PRDM1, PSMD10, IL1B, EDN1, C1QBP, RUNX3, PLK1, HDAC2, SMAD3, RELA, DICER1, DNMT3A, FOXL2, HIF1A, HES5, FOXO1, HSF1, SMAD2, HEY1, ESR2, PPARA, NFKB2, POU5F1, HDAC1, FOXP3, EZH2, SIRT1, ID2, SMAD4, EHMT2, TWIST1, DNMT3B, NR0B2, ZNF366, TP63, KLF10, GATA6, SUV39H2, DLL4, HAMP, NODAL, AHRR, MAF, MBD2 |
| negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle | biological_process | RB1 |
| negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological_process | JUN |
| negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | biological_process | HEY1 |
| negative regulation of transcription involved in G1/S transition of mitotic cell cycle | biological_process | RB1 |
| negative regulation of transcription regulatory region DNA binding | biological_process | HEY1, PPARA |
| negative regulation of transcription, DNA-templated | biological_process | GCLC, SRC, GATA3, BCL6, NR2F2, BMP4, DNMT1, WNT5A, HMGA2, PPARG, CTNNB1, BRCA1, NFKB1, HMGA1, AHR, CDKN1B, NOTCH1, ID1, CDKN2A, VDR, WT1, ZEB1, GREM1, JUN, TGFB1, CLOCK, TP53, SUV39H1, TNF, BIRC5, ENO1, SMAD7, RB1, KLF11, SNAI1, IL4, HDAC2, RELA, NRG1, FOXL2, FOXP1, HES5, FOXO1, GAS6, PLCB1, SMAD2, HEY1, ADIPOQ, SET, HDAC1, FOXP3, EZH2, SIRT1, ID2, SMAD4, TWIST1, DNMT3B, NR0B2, TP63, KLF10, GATA6, SUV39H2, PAX2, WNT4, DNMT3L, TBPL2, MBD2 |
| negative regulation of transformation of host cell by virus | biological_process | FBLN1 |
| negative regulation of transforming growth factor beta production | biological_process | IL13 |
| negative regulation of transforming growth factor beta receptor signaling pathway | biological_process | ENG, TGFB1, SMAD7, TGFB1I1, WNT1, SMAD3, SMAD2, SIRT1, ADAM17, HTRA1 |
| negative regulation of transforming growth factor beta1 production | biological_process | GATA6 |
| negative regulation of transforming growth factor beta2 production | biological_process | CDH3, GATA6 |
| negative regulation of transforming growth factor-beta secretion | biological_process | FBLN1, FN1, LILRB1 |
| negative regulation of translation | biological_process | TOB1, IGFBP5, TIA1, WT1, ANG, EIF4EBP1, DAPK1 |
| negative regulation of translational initiation | biological_process | EIF3E, EIF4EBP1 |
| negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological_process | FSTL3 |
| negative regulation of transporter activity | biological_process | INSR |
| negative regulation of triglyceride metabolic process | biological_process | ESR1 |
| negative regulation of trophoblast cell migration | biological_process | TIMP1, NODAL |
| negative regulation of tumor necrosis factor (ligand) superfamily member 11 production | biological_process | LTF |
| negative regulation of tumor necrosis factor biosynthetic process | biological_process | IL10, GHRL, ERRFI1, LILRB1 |
| negative regulation of tumor necrosis factor production | biological_process | IL10, PTGER4, AXL, GSTP1, LGALS9, TLR4, GAS6, HSF1, ADIPOQ, FOXP3, PTPN22, TWIST1 |
| negative regulation of tumor necrosis factor secretion | biological_process | PTGER4 |
| negative regulation of tumor necrosis factor-mediated signaling pathway | biological_process | GSTP1, APOA1, GAS6, F2RL1, ADIPOQ |
| negative regulation of type 2 immune response | biological_process | BCL6, STAT6, CCR2 |
| negative regulation of type B pancreatic cell development | biological_process | GSK3B |
| negative regulation of type IV hypersensitivity | biological_process | IL20RB |
| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | biological_process | CCNB1, PSMD9, PSMD10 |
| negative regulation of ubiquitin-protein transferase activity | biological_process | SMAD7, PARK7, LIMK1, CDKN2A |
| negative regulation of ubiquitin-specific protease activity | biological_process | PARK7 |
| negative regulation of vascular endothelial growth factor receptor signaling pathway | biological_process | PDCD6 |
| negative regulation of vascular endothelial growth factor signaling pathway | biological_process | XDH, DCN |
| negative regulation of vascular permeability | biological_process | ADM, ANGPT1 |
| negative regulation of vascular smooth muscle cell proliferation | biological_process | CDKN1B, GPER1 |
| negative regulation of vascular wound healing | biological_process | SERPINE1 |
| negative regulation of vasculogenesis | biological_process | XDH |
| negative regulation of vasoconstriction | biological_process | LEP, ADM, HIF1A, CX3CL1 |
| negative regulation of vasodilation | biological_process | CRP |
| negative regulation of very-low-density lipoprotein particle remodeling | biological_process | APOA1, APOA2 |
| negative regulation of viral entry into host cell | biological_process | PTX3, APCS |
| negative regulation of viral genome replication | biological_process | CCL5, LTF, TNF, SLPI, ISG20 |
| negative regulation of viral process | biological_process | MBL2, LTF, APCS |
| negative regulation of vitamin D biosynthetic process | biological_process | NFKB1, SNAI1 |
| negative regulation of voltage-gated calcium channel activity | biological_process | CRHR1, DRD2 |
| negative regulation of white fat cell proliferation | biological_process | IL4 |
| negative regulation of Wnt protein secretion | biological_process | OPRM1 |
| negative regulation of Wnt signaling pathway | biological_process | CCND1, DKK1, SFRP4 |
| negative regulation of Wnt-Frizzled-LRP5/6 complex assembly | biological_process | DKK1 |
| negative regulation of wound healing | biological_process | FGF2, GJA1, SERPINE1, APCS, SMAD3, WNT4 |
| negative thymic T cell selection | biological_process | FAS, CD74, CCR7 |
| nephric duct development | biological_process | HNF1B |
| nephric duct formation | biological_process | GATA3, HNF1B, PAX2 |
| nephric duct morphogenesis | biological_process | GATA3 |
| nephrogenic mesenchyme morphogenesis | biological_process | SMAD4 |
| nephron development | biological_process | ITGA3, JAG1, WNT4 |
| nephron tubule formation | biological_process | CTNNB1 |
| nerve development | biological_process | NRP1, NRP2, DICER1, SEMA3A |
| nerve growth factor processing | biological_process | NGF, PCSK5 |
| nervous system development | biological_process | GSK3B, GATA3, INHBA, FGF2, VEGFA, STAT3, AKT1, CTNNB1, NME1, CNTF, CXCL1, STMN1, PTN, MDK, BDNF, L1CAM, ZEB1, INHA, ERBB2, ARID1A, NRP1, FOS, MSI1, KALRN, NRP2, CDC42, PTEN, NRG1, NTRK2, HES5, DPYSL2, BAX, LIMK1, GPER1, JAG1, IGSF8, PTPRR, NAGLU, DLX5, DLL4, SEMA3A, CHD5, NODAL, OLFM1, SEMA3C |
| netrin-activated signaling pathway | biological_process | PTK2 |
| neural crest cell development | biological_process | MAPK1, EDNRA, EDN1, NRG1 |
| neural crest cell differentiation | biological_process | SMAD4 |
| neural crest cell migration | biological_process | KITLG, LAMA5, HIF1A, SEMA3A, SEMA3C |
| neural crest cell migration involved in autonomic nervous system development | biological_process | NRP1, SEMA3A |
| neural crest cell migration involved in heart formation | biological_process | FOLR1 |
| neural crest cell migration involved in sympathetic nervous system development | biological_process | SEMA3A |
| neural fold elevation formation | biological_process | HIF1A |
| neural fold formation | biological_process | NODAL |
| neural nucleus development | biological_process | HOXB2 |
| neural plate development | biological_process | CTNNB1 |
| neural tube closure | biological_process | BMP4, WNT5A, SDC4, ADM, ARID1A, TWIST1, PAX2 |
| neural tube development | biological_process | WNT5A, NOTCH1, HES5, SEMA3C |
| neuroblast differentiation | biological_process | BCHE |
| neurofilament cytoskeleton organization | biological_process | SOD1 |
| neurogenesis | biological_process | WNT5A, WNT2, WNT1, NRG1 |
| neurological system process involved in regulation of systemic arterial blood pressure | biological_process | DRD2 |
| neuromuscular junction development | biological_process | TNC, ERBB2, COL4A1, NTRK2 |
| neuromuscular process | biological_process | UCHL1 |
| neuromuscular synaptic transmission | biological_process | P2RX3 |
| neuron apoptotic process | biological_process | BCL2, ERBB3, CASP3, FAS, RB1, TNFRSF21, BCL2L1, BAX, ATM, TP63 |
| neuron cellular homeostasis | biological_process | TYRO3 |
| neuron death | biological_process | CCR2, PLAU |
| neuron development | biological_process | CNTF, LIF, NRP1, WNT1, TGFB2 |
| neuron differentiation | biological_process | GATA3, DNMT1, WNT5A, SHC1, CTNNB1, WNT2, NOTCH1, ID1, CASP3, GATA2, EFNA1, RB1, DNMT3A, NTRK2, HES5, EMX2, PTPRR, WNT4 |
| neuron fate commitment | biological_process | BMP4, NOTCH1, GATA2, WNT1, TGFB2, NRG1, ID2, SMAD4 |
| neuron fate determination | biological_process | WNT1, CDC42 |
| neuron maturation | biological_process | RB1 |
| neuron migration | biological_process | FGFR1, GATA3, NR2F2, ITGA3, GJA1, CTNNB1, AXL, GATA2, CXCL12, HSP90AA1, FYN, NRP1, PTK2, NTRK2, GAS6, BAX, CXCR4, TWIST1, SEMA3A |
| neuron projection development | biological_process | FGFR1, CDH1, HMGB1, SHC1, MAP2, NCAM1, STMN1, TNC, ITGB1, RB1, IL6, PTEN, AGER, UCN, NPY |
| neuron projection extension | biological_process | AURKA, POSTN |
| neuron projection morphogenesis | biological_process | WNT5A, CLU, GJA1, LIFR, NTF4, NGF, SGK1, RAC1, DICER1, PAK1, ATP7A |
| neuron projection regeneration | biological_process | ADM, APOA1, APOE |
| neuron recognition | biological_process | CXCR4 |
| neuron remodeling | biological_process | NTN4 |
| neuron-neuron synaptic transmission | biological_process | DRD2, PTEN |
| neuronal action potential | biological_process | GPER1, P2RX3 |
| neuronal signal transduction | biological_process | OLFM1 |
| neuronal stem cell population maintenance | biological_process | NOTCH1, SOX2, HES5, FOXO1, JAG1, MMP24 |
| neuropeptide signaling pathway | biological_process | OPRM1, SSTR1, UCN, KISS1R, NPY |
| neurotransmitter catabolic process | biological_process | MAOA, COMT |
| neurotransmitter metabolic process | biological_process | MAOA |
| neurotransmitter receptor metabolic process | biological_process | NRG1 |
| neurotransmitter secretion | biological_process | WNT7A |
| neurotransmitter transport | biological_process | SLC6A4, SLC6A2 |
| neurotrophin signaling pathway | biological_process | NTRK2 |
| neurotrophin TRK receptor signaling pathway | biological_process | SRC, CASP3, NGF |
| neutral lipid catabolic process | biological_process | LIPC |
| neutrophil activation | biological_process | CCL5, CXCL8, CXCR2, F2RL1 |
| neutrophil activation involved in immune response | biological_process | FCER1G |
| neutrophil apoptotic process | biological_process | IFNG, IL6 |
| neutrophil chemotaxis | biological_process | CCL5, LGALS3, CXCL8, CCL3, SAA1, CXCR2, CCL2, FCER1G, IFNG, CCL25, CCL22, CCL16, IL1B, ITGB2, EDN1, TGFB2, CCL7, CX3CL1, CCL17, CCL11 |
| neutrophil clearance | biological_process | HMGB1, ANXA1 |
| neutrophil homeostasis | biological_process | ANXA1 |
| neutrophil mediated immunity | biological_process | ACE, IL6R, CXCL5, IL6, ADAM17, CXCL6 |
| neutrophil mediated killing of gram-positive bacterium | biological_process | CTSG |
| NFAT protein import into nucleus | biological_process | PIK3R1 |
| nicotinamide metabolic process | biological_process | PTGS2 |
| nicotinamide riboside catabolic process | biological_process | PNP |
| NIK/NF-kappaB signaling | biological_process | NFKB1, PSMD9, PSMD10, NFKB2 |
| nitric oxide biosynthetic process | biological_process | NOS2, AKT1, NOS3, ARG2, CYP1B1 |
| nitric oxide mediated signal transduction | biological_process | NOS2, CD36, FPR1, AGTR2, NOS3, APOE |
| nitric oxide production involved in inflammatory response | biological_process | TLR4 |
| nitric oxide storage | biological_process | GSTP1 |
| nitric oxide transport | biological_process | EDN1 |
| nitrobenzene metabolic process | biological_process | GSTM1 |
| NK T cell proliferation | biological_process | IL15 |
| NMDA glutamate receptor clustering | biological_process | APOE |
| nodal signaling pathway | biological_process | SMAD3, SMAD2, NODAL |
| nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological_process | NODAL |
| non-canonical Wnt signaling pathway | biological_process | WNT5A, WNT7A, RAC1, WNT4, SFRP4 |
| non-canonical Wnt signaling pathway via JNK cascade | biological_process | WNT5A |
| non-canonical Wnt signaling pathway via MAPK cascade | biological_process | WNT4 |
| norepinephrine biosynthetic process | biological_process | GATA3 |
| norepinephrine metabolic process | biological_process | AKR1B1, ATP7A |
| norepinephrine transport | biological_process | SLC6A2 |
| Notch receptor processing | biological_process | ADAM17, JAG1, DLL4, NOTCH4 |
| Notch signaling involved in heart development | biological_process | NOTCH1, SNAI1, HEY1, JAG1, DLL4 |
| Notch signaling pathway | biological_process | KRT19, CDKN1B, NOTCH1, ANXA4, HNF1B, MDK, TGFB1, MYC, PTP4A3, IL2RA, FCER2, HES5, HEY1, KAT2B, ADAM17, NR0B2, TP63, JAG1, DLL4, NOTCH4, TIMP4 |
| Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation | biological_process | NOTCH1 |
| notochord development | biological_process | YAP1 |
| notochord formation | biological_process | EFNA1 |
| notochord morphogenesis | biological_process | WNT5A |
| nuclear fragmentation involved in apoptotic nuclear change | biological_process | GPER1 |
| nuclear migration | biological_process | CDC42 |
| nuclear transport | biological_process | HMGA1 |
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | biological_process | EIF3E, RPL41 |
| nuclear-transcribed mRNA poly(A) tail shortening | biological_process | MLH1 |
| nucleic acid phosphodiester bond hydrolysis | biological_process | ANG, PMS2 |
| nucleobase-containing compound metabolic process | biological_process | PNP, DPYSL2 |
| nucleobase-containing small molecule interconversion | biological_process | TXN, NME1 |
| nucleocytoplasmic transport | biological_process | SET |
| nucleoside diphosphate phosphorylation | biological_process | NME1 |
| nucleoside metabolic process | biological_process | PNP |
| nucleoside triphosphate biosynthetic process | biological_process | NME1 |
| nucleosome assembly | biological_process | H2AFX, SET, HIST3H3, HIST2H3A |
| nucleosome disassembly | biological_process | HMGA1, ARID1A, SET |
| nucleosome mobilization | biological_process | ARID1A |
| nucleotide metabolic process | biological_process | NME1, ADA, FHIT |
| nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_process | RELA, NOD2 |
| nucleotide-binding oligomerization domain containing signaling pathway | biological_process | MAP3K7, NOD2, NOD1 |
| nucleotide-excision repair | biological_process | BRCA2, TP53, OGG1 |
| nucleotide-excision repair, DNA damage recognition | biological_process | COPS5 |
| nucleotide-excision repair, DNA gap filling | biological_process | PCNA, XRCC1 |
| nucleotide-excision repair, DNA incision | biological_process | PCNA, OGG1 |
| nucleotide-excision repair, DNA incision, 5'-to lesion | biological_process | PCNA |
| nucleus localization | biological_process | CDC42 |
| nucleus organization | biological_process | PRM1 |
| O-glycan processing | biological_process | MUC1, MUC16, MUC17, MUC4 |
| obsolete transformed cell apoptotic process | biological_process | TNF, BAX |
| odontogenesis | biological_process | INHBA, BMP4, FGFR2, CSF1, SDC1, TGFB2, TWIST1, AQP5 |
| odontogenesis of dentin-containing tooth | biological_process | ITGA6, BMP4, CTNNB1, CTNNA1, TNC, ADM, BSG, CA2, LAMA5, BCL2L11, HDAC2, BAX, HDAC1, TP63 |
| olfactory bulb development | biological_process | CSF1R, DPYSL2, ID2, SEMA3A |
| olfactory bulb interneuron development | biological_process | WNT5A |
| olfactory pit development | biological_process | DLX5 |
| oligodendrocyte apoptotic process | biological_process | TP53, TNFRSF21 |
| oligodendrocyte development | biological_process | GSTP1, TGFB1, HES5, ID2 |
| oligodendrocyte differentiation | biological_process | NOTCH1, ERBB2, NRG1, NTRK2 |
| omega-hydroxylase P450 pathway | biological_process | CYP2C19, CYP1A2, CYP1A1, CYP1B1 |
| oncogene-induced cell senescence | biological_process | HMGA2, HMGA1 |
| oncostatin-M-mediated signaling pathway | biological_process | IL6ST, LIFR |
| one-carbon metabolic process | biological_process | MAT2A, CA2 |
| oocyte development | biological_process | BCL2, CTNNB1, ATM, WNT4 |
| oocyte differentiation | biological_process | LGR5 |
| oocyte growth | biological_process | GDF9, FOXL2 |
| oocyte maturation | biological_process | CCNB1, BRCA2, ANG |
| oogenesis | biological_process | MLH1, SRC |
| operant conditioning | biological_process | TACR2, TACR1 |
| opioid receptor signaling pathway | biological_process | OPRM1 |
| opsonization | biological_process | MBL2, PTX3, CRP |
| optic chiasma development | biological_process | PAX2 |
| optic cup formation involved in camera-type eye development | biological_process | WNT5A, ARID1A |
| optic cup morphogenesis involved in camera-type eye development | biological_process | PAX2 |
| optic nerve development | biological_process | PAX2 |
| optic nerve morphogenesis | biological_process | PAX2 |
| optic nerve structural organization | biological_process | PAX2 |
| orbitofrontal cortex development | biological_process | FGFR1, FGFR2, DRD2 |
| organ growth | biological_process | BCL2, FGFR2, SMAD2 |
| organ induction | biological_process | FGFR1, BMP4, HOXA11, FGF1 |
| organelle transport along microtubule | biological_process | CDC42 |
| organic acid metabolic process | biological_process | STAR, CYP17A1 |
| organic anion transport | biological_process | SLC22A23 |
| organic substance metabolic process | biological_process | PGM1 |
| organophosphate catabolic process | biological_process | PON1 |
| ossification | biological_process | BCL2, BMP4, MMP13, ALOX15, MMP9, RASSF2, SPP1, CSF1, SPARC, MMP14, PTN, BMP6, EGFR, FSTL3, AHSG, LTF, IGF2, COL5A2, RUNX3, TWIST1, DLX5, STC1 |
| ossification involved in bone maturation | biological_process | RHOA |
| ossification involved in bone remodeling | biological_process | TGFB1 |
| osteoblast development | biological_process | ESR1, SMAD3 |
| osteoblast differentiation | biological_process | BMP4, MMP13, GJA1, IGFBP3, AKT1, CCL3, SPP1, IGFBP5, VCAN, BMP6, TNC, SOX2, ATP5B, CYR61, SNAI1, CAT, SMAD3, TWIST1, DLX5, CYP24A1, CREB3L1 |
| osteoclast development | biological_process | SRC, ANXA2, FOXP1 |
| osteoclast differentiation | biological_process | CTNNB1, CSF1, TNF, CSF1R, FOXP1 |
| osteoclast proliferation | biological_process | CSF1 |
| otic placode formation | biological_process | NRP1 |
| otic vesicle development | biological_process | GATA3 |
| otic vesicle formation | biological_process | FGFR2 |
| outer ear morphogenesis | biological_process | FGFR1, MAPK1, TWIST1 |
| outer mitochondrial membrane organization | biological_process | BAX |
| outflow tract morphogenesis | biological_process | VEGFA, ATF2, JUN, CLDN5, HIF1A, SEMA3C |
| outflow tract septum morphogenesis | biological_process | FGFR2, GATA6 |
| ovarian cumulus expansion | biological_process | BMPR1B |
| ovarian follicle atresia | biological_process | FAS |
| ovarian follicle development | biological_process | BCL2, INHBA, VEGFA, BMP4, KIT, AHR, CTNNA1, KITLG, MMP14, ANG, SOD1, INHA, CAPN5, FSHB, ICAM1, BCL2L1, FOXL2, BAX, ESR2, SMAD4 |
| oviduct development | biological_process | CTNNB1, WNT7A |
| ovulation | biological_process | HPGD, IL1R1, PTGS2, CYP17A1, IL1B |
| ovulation cycle | biological_process | SERPINF1, AXL, FAS, BMPR1B, TYRO3, TIMP4 |
| ovulation cycle process | biological_process | LHCGR, MSTN |
| ovulation from ovarian follicle | biological_process | PLA2G4A, LEP, NOS3, SIRT1 |
| oxalate transport | biological_process | SLC26A8 |
| oxaloacetate metabolic process | biological_process | ACLY |
| oxidation-reduction process | biological_process | XDH, AKR1B1, NDUFS1, AKR1D1, TXN, NOS2, PRDX6, APEX1, ALOX15, GPX3, CYP19A1, HPGD, MTHFR, CYP2A6, HMOX1, HSD3B2, HSD17B1, IDO1, VCAM1, CYP2B6, MAOA, LPO, PTGS1, NOS3, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, HSD17B2, AKR1C3, ALDH3A2, AKR1C2, CYP17A1, MT-CO2, CYP2E1, CYP11A1, SOD1, CYP1A2, ABCC4, CYP26A1, CP, GPX1, CAT, CYP1A1, MPO, ADI1, LOXL4, PAX2, AKR1C1, HSD17B7, HSD11B2, LOXL1, CYP1B1, PTGES2, TET3, SRD5A1, CYP24A1, TET2, TET1 |
| oxidative deethylation | biological_process | CYP1A2 |
| oxidative demethylation | biological_process | CYP1A2 |
| oxidative phosphorylation | biological_process | MSH2 |
| oxidative stress-induced premature senescence | biological_process | TP53 |
| oxygen homeostasis | biological_process | HIF1A |
| oxygen transport | biological_process | MYC |
| p38MAPK cascade | biological_process | LGALS9 |
| palate development | biological_process | INHBA, WNT5A, CLDN5, WNT7A, SNAI1, SMAD2, SMAD4, TWIST1, DLX5 |
| pancreas development | biological_process | CTNNB1, SMAD2, GATA6 |
| pancreas morphogenesis | biological_process | NR5A2 |
| pancreatic A cell differentiation | biological_process | GATA6 |
| pancreatic juice secretion | biological_process | UCN, AQP5 |
| paramesonephric duct development | biological_process | WNT4 |
| parathyroid gland development | biological_process | GATA3 |
| parathyroid hormone secretion | biological_process | GATA3 |
| paraxial mesoderm development | biological_process | FGFR1, YAP1 |
| paraxial mesoderm formation | biological_process | WNT5A |
| paraxial mesoderm morphogenesis | biological_process | SMAD3, SMAD2 |
| parturition | biological_process | CRHR1, MMP13, HPGD, PTGFR, CRH |
| pathway-restricted SMAD protein phosphorylation | biological_process | TGFB1, SMAD7, TGFB2 |
| pattern recognition receptor signaling pathway | biological_process | CD36 |
| pattern specification process | biological_process | CDX1, ZEB1, SMAD2, TP63 |
| penile erection | biological_process | EDNRA |
| pentacyclic triterpenoid metabolic process | biological_process | IL1B |
| peptide antigen assembly with MHC class II protein complex | biological_process | HLA-DRB1, HLA-DRA |
| peptide biosynthetic process | biological_process | PCSK5 |
| peptide catabolic process | biological_process | MMP13, ACE |
| peptide cross-linking | biological_process | FN1, ANXA1, THBS1 |
| peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan | biological_process | BGN, SPOCK2, DCN |
| peptide hormone processing | biological_process | CGA, FSHB, LHB, PCSK5 |
| peptide hormone secretion | biological_process | EDN1, SMPD3 |
| peptide metabolic process | biological_process | MME, CMA1 |
| peptidyl-cysteine S-nitrosylation | biological_process | NOS2 |
| peptidyl-lysine acetylation | biological_process | KAT2B, SIRT1 |
| peptidyl-lysine deacetylation | biological_process | SIRT1 |
| peptidyl-lysine dimethylation | biological_process | EHMT2 |
| peptidyl-lysine modification | biological_process | ATP7A |
| peptidyl-methionine modification | biological_process | APOA1, APOA2 |
| peptidyl-serine autophosphorylation | biological_process | ATM |
| peptidyl-serine phosphorylation | biological_process | GSK3B, BCL2, SRC, MAPK1, AKT1, TDGF1, MTOR, CHEK2, PRKCB, SGK1, PLK1, GAS6, ATM |
| peptidyl-threonine phosphorylation | biological_process | GSK3B, BCL2, MAPK1, AKT1, MTOR |
| peptidyl-tyrosine autophosphorylation | biological_process | SRC, KDR, JAK1, TYK2, INSR, IGF1R, FYN, PTK2 |
| peptidyl-tyrosine dephosphorylation | biological_process | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR |
| peptidyl-tyrosine phosphorylation | biological_process | FGFR1, SRC, FGF2, MET, FGFR2, KIT, ERBB3, KDR, FLT4, CSF2RB, PDGFRA, AXL, FLT1, FLT3, INSR, HSP90AA1, EGFR, FGF1, ERBB2, FYN, MAP2K7, EGF, CSF2, IL5, CSF1R, PTK2, NRG1, NTRK2, TYRO3, TEK, MST1R |
| pericardium development | biological_process | SMAD3, SMAD2 |
| pericardium morphogenesis | biological_process | WNT5A, NOTCH1, DLL4 |
| peripheral nervous system axon regeneration | biological_process | TNC, APOA1 |
| peripheral nervous system development | biological_process | ERBB3, ALDH3A2, ERBB2, NRG1 |
| peripheral nervous system myelin formation | biological_process | DICER1 |
| peripheral nervous system myelin maintenance | biological_process | AKT1, SOD1 |
| peripheral nervous system neuron development | biological_process | RUNX3, NTRK2 |
| peristalsis | biological_process | DRD2, P2RX3 |
| PERK-mediated unfolded protein response | biological_process | CXCL8, IGFBP1, CCL2, NFE2L2 |
| peroxisome proliferator activated receptor signaling pathway | biological_process | PPARG, ACTN4 |
| Peyer's patch development | biological_process | ADA, ID2 |
| phagocytosis | biological_process | AXL, GATA2, PECAM1, PIK3CA, ANXA1, GAS6 |
| phagocytosis, engulfment | biological_process | FCER1G, RAC1, AIF1 |
| phagocytosis, recognition | biological_process | CD36, SCARB1 |
| pharyngeal arch artery morphogenesis | biological_process | FOLR1 |
| pharyngeal system development | biological_process | GATA3 |
| phenol-containing compound metabolic process | biological_process | STAR, CYP17A1 |
| phenylethylamine metabolic process | biological_process | MAOA |
| phosphate ion homeostasis | biological_process | SFRP4 |
| phosphate-containing compound metabolic process | biological_process | TGFB1 |
| phosphatidic acid biosynthetic process | biological_process | PLA2G4A, PLA2G2A |
| phosphatidic acid metabolic process | biological_process | LIPC, PLA2G2A |
| phosphatidylcholine acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
| phosphatidylcholine biosynthetic process | biological_process | APOA1, APOA2, PEMT |
| phosphatidylcholine catabolic process | biological_process | LIPC |
| phosphatidylcholine metabolic process | biological_process | CETP, LIPC, PON1 |
| phosphatidylethanolamine acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
| phosphatidylethanolamine biosynthetic process | biological_process | ALOX15 |
| phosphatidylethanolamine metabolic process | biological_process | LIPC |
| phosphatidylglycerol acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A |
| phosphatidylinositol 3-kinase signaling | biological_process | GATA3, PIK3R1, ERBB3, IGF1, IGF1R, ERBB2, EDN1, C1QBP, TYRO3 |
| phosphatidylinositol acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
| phosphatidylinositol biosynthetic process | biological_process | FGF2, PIK3R1, PIK3CA, PTEN |
| phosphatidylinositol dephosphorylation | biological_process | PTEN |
| phosphatidylinositol metabolic process | biological_process | DRD2, CSF1R, PLCB1 |
| phosphatidylinositol phosphorylation | biological_process | FGFR1, FGF2, FGFR2, PIK3R1, KIT, ERBB3, PDGFRA, KITLG, PIK3CA, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, NRG1, IRS2 |
| phosphatidylinositol-3-phosphate biosynthetic process | biological_process | FGFR1, FGF2, FGFR2, PIK3R1, PIK3CA, FGF1, TLR9, ATM, IRS2 |
| phosphatidylinositol-mediated signaling | biological_process | FGFR1, FGF2, FGFR2, PIK3R1, KIT, AKT1, ERBB3, PDGFRA, KITLG, PIK3CA, MTOR, IGF1, EGFR, FGF1, IGF1R, NGF, PDGFA, ERBB2, FYN, EGF, CSF1R, PTEN, NRG1, IRS2, RHOA |
| phosphatidylserine acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
| phosphatidylserine metabolic process | biological_process | LIPC |
| phosphoanandamide dephosphorylation | biological_process | PTPN22 |
| phospholipase C-activating angiotensin-activated signaling pathway | biological_process | AGTR1 |
| phospholipase C-activating dopamine receptor signaling pathway | biological_process | DRD2 |
| phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway | biological_process | HRH4 |
| phospholipase C-activating G-protein coupled receptor signaling pathway | biological_process | F2R, OPRM1, FPR1, AGTR1, CXCR2, TACR1, LHCGR, ESR1, KISS1R |
| phospholipase D-activating G-protein coupled receptor signaling pathway | biological_process | EDN1 |
| phospholipid biosynthetic process | biological_process | PLA2G16, PEMT |
| phospholipid catabolic process | biological_process | PLA2G4A, APOA2 |
| phospholipid efflux | biological_process | APOA1, APOA2, APOE |
| phospholipid homeostasis | biological_process | CETP, APOA1 |
| phospholipid metabolic process | biological_process | PLA2G4A, PLCD1, PLA2G2A, APOA1, RARRES3, GATA6, PLA2G16, PEMT |
| phospholipid transport | biological_process | CETP, APOA1, SCARB1 |
| phosphorylation | biological_process | GSK3B, FGFR1, SRC, MET, STAT3, MAPK1, FGFR2, KIT, AKT1, ERBB3, NME1, KDR, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, PIK3CA, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, PLK1, PTK2, NTRK2, TYRO3, TEK, PAK1, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2 |
| photoperiodism | biological_process | CLOCK |
| photoreceptor cell maintenance | biological_process | PROM1 |
| phthalate metabolic process | biological_process | SRD5A2, STAR, CYP17A1 |
| phytol metabolic process | biological_process | ALDH3A2 |
| pigment granule organization | biological_process | BCL2 |
| pigmentation | biological_process | BCL2, KIT, DRD2, ATP7A |
| pinocytosis | biological_process | AHSG |
| pituitary gland development | biological_process | CDH1, BMP4, GATA2, SOX2, SRD5A1 |
| placenta blood vessel development | biological_process | NR2F2, ARID1A, SOCS3 |
| placenta development | biological_process | PPARG, LEP, HSD17B2, ANG, SOD1, ADA, PTK2, HTRA1, NODAL, DCN |
| planar cell polarity pathway involved in axis elongation | biological_process | WNT5A |
| planar cell polarity pathway involved in cardiac muscle tissue morphogenesis | biological_process | WNT5A |
| planar cell polarity pathway involved in cardiac right atrium morphogenesis | biological_process | WNT5A |
| planar cell polarity pathway involved in gastrula mediolateral intercalation | biological_process | WNT5A |
| planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation | biological_process | WNT5A |
| planar cell polarity pathway involved in neural tube closure | biological_process | WNT5A |
| planar cell polarity pathway involved in outflow tract morphogenesis | biological_process | WNT5A |
| planar cell polarity pathway involved in pericardium morphogenesis | biological_process | WNT5A |
| planar cell polarity pathway involved in ventricular septum morphogenesis | biological_process | WNT5A |
| plasma cell differentiation | biological_process | LGALS1 |
| plasma lipoprotein particle clearance | biological_process | CD36 |
| plasma membrane copper ion transport | biological_process | ATP7A |
| plasmacytoid dendritic cell activation | biological_process | HMGB1 |
| plasminogen activation | biological_process | FGA, PLAT |
| platelet activating factor biosynthetic process | biological_process | PLA2G4A |
| platelet activation | biological_process | SRC, CD40LG, F2R, MAPK1, PIK3R1, AKT1, CD40, AXL, SAA1, PIK3CA, FCER1G, ITGB3, FGA, PRKCB, FYN, IL6, RAC1, GAS6, TYRO3, CX3CL1, RHOA |
| platelet aggregation | biological_process | PDGFRA, ITGB3, FGA, HSPB1, GAS6, TYRO3, ACTB |
| platelet degranulation | biological_process | VEGFA, CLU, CD36, SPARC, HGF, PECAM1, SELP, TIMP3, VEGFC, FN1, IGF1, ITGB3, TGFB1, ACTN4, A2M, SOD1, FGA, SERPINA1, AHSG, APOA1, TIMP1, PDGFA, ABCC4, SERPINE1, THBS1, FIGF, EGF, IGF2, TF, A1BG, PSAP, TGFB2, GAS6, RARRES2 |
| platelet dense granule organization | biological_process | F2R |
| platelet formation | biological_process | CASP3 |
| platelet-derived growth factor receptor signaling pathway | biological_process | SRC, PDGFRA, PLAT, PDGFA, NRP1, PTEN |
| platelet-derived growth factor receptor-alpha signaling pathway | biological_process | PDGFRA |
| plus-end-directed vesicle transport along microtubule | biological_process | KIFAP3 |
| PMA-inducible membrane protein ectodomain proteolysis | biological_process | ADAM17 |
| pointed-end actin filament capping | biological_process | TMOD3 |
| polarity specification of proximal/distal axis | biological_process | NODAL |
| polarized epithelial cell differentiation | biological_process | TP63 |
| polyketide metabolic process | biological_process | IL1B |
| polysaccharide assembly with MHC class II protein complex | biological_process | HLA-DRB1, HLA-DRA |
| polysaccharide digestion | biological_process | AMY2A |
| porphyrin-containing compound metabolic process | biological_process | CYP1A2, CYP1A1 |
| positive chemotaxis | biological_process | FGF2, VEGFA, MET, BMP4, CCL5, HMGB1, LGALS3, MIF, CCL3, HGF, SAA1, VEGFC, CXCL12, NRP1, CCL16, FIGF, ANGPT1 |
| positive regulation by host of viral process | biological_process | CFL1, APOE |
| positive regulation by host of viral transcription | biological_process | JUN |
| positive regulation of acetylcholine secretion, neurotransmission | biological_process | TACR2 |
| positive regulation of acrosome reaction | biological_process | PLCB1 |
| positive regulation of actin cytoskeleton reorganization | biological_process | TEK |
| positive regulation of actin filament bundle assembly | biological_process | ID1, LIMK1 |
| positive regulation of actin filament depolymerization | biological_process | F2RL1 |
| positive regulation of actin filament polymerization | biological_process | ALOX15, MTOR, CCL21, ICAM1, RAC1, CCR7, CCL11 |
| positive regulation of action potential | biological_process | TACR1 |
| positive regulation of activated T cell autonomous cell death | biological_process | LGALS9 |
| positive regulation of activated T cell proliferation | biological_process | HMGB1, IGFBP2, IL12B, IGF1, IGF2, IL2RA, IL4, IL18, AGER, IL23A, IL2 |
| positive regulation of activation of JAK2 kinase activity | biological_process | CCL5, IL12B, IL23A |
| positive regulation of activation of Janus kinase activity | biological_process | IL6R |
| positive regulation of activation of membrane attack complex | biological_process | C3 |
| positive regulation of activation-induced cell death of T cells | biological_process | TGFB2 |
| positive regulation of activin receptor signaling pathway | biological_process | NODAL |
| positive regulation of acute inflammatory response | biological_process | IL6ST, IL6, ADAM8 |
| positive regulation of adaptive immune response | biological_process | IL6ST, SIRT1 |
| positive regulation of adenylate cyclase activity | biological_process | TIMP2 |
| positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway | biological_process | CRHR1, GPER1 |
| positive regulation of adipose tissue development | biological_process | SIRT1 |
| positive regulation of aldosterone biosynthetic process | biological_process | BMP6, WNT4 |
| positive regulation of aldosterone secretion | biological_process | BMP6 |
| positive regulation of alkaline phosphatase activity | biological_process | ITGA2, SMAD3 |
| positive regulation of alpha-beta T cell differentiation | biological_process | PNP, ADA, IHH |
| positive regulation of alpha-beta T cell proliferation | biological_process | CCR2 |
| positive regulation of androgen receptor activity | biological_process | PARK7 |
| positive regulation of angiogenesis | biological_process | FGF2, VEGFA, WNT5A, CCL5, CHI3L1, F3, CXCL8, BRCA1, KDR, CXCR3, ENG, GATA2, HGF, FLT1, HMOX1, CMA1, NOS3, ADM, VEGFC, GREM1, FGF1, PRKCB, IL1A, C3, HSPB1, PDCD6, ANGPT2, SERPINE1, THBS1, IL1B, ITGB2, C5, HIF1A, TEK, SIRT1, TWIST1, GATA6, CX3CL1, CYP1B1, NODAL, CCL11 |
| positive regulation of anoikis | biological_process | CHEK2 |
| positive regulation of antigen processing and presentation of peptide antigen via MHC class I | biological_process | ABCB1 |
| positive regulation of antral ovarian follicle growth | biological_process | PTGER4 |
| positive regulation of apoptotic cell clearance | biological_process | C4A, CCL2, C3 |
| positive regulation of apoptotic DNA fragmentation | biological_process | BAX |
| positive regulation of apoptotic process | biological_process | GSK3B, HSPD1, SRC, ITGA6, BCL6, BMP4, PLA2G4A, HMGA2, PPARG, IGF2R, HMGB1, CLU, IGFBP3, MMP9, ANXA5, AKT1, CTNNB1, TNFSF10, NOTCH1, CASP3, RASSF2, FASLG, FAS, IDO1, CTLA4, WT1, PTN, ADM, PTGS2, ITGB1, JUN, TGFB1, ANXA1, SOD1, NGF, TP53, TNF, LATS1, CYR61, KLF11, TLR3, BCL2L11, KALRN, IL1B, LTA, IL6, RAC1, C1QBP, PTEN, BCL2L1, FOXL2, HIF1A, FOXO1, BAX, ESR2, SIRT1, ATM, AGER, GPER1, CDKN2A, CYP1B1, SFRP4, KLRK1, LILRB1 |
| positive regulation of apoptotic process by virus | biological_process | CCR2, BCL2L11 |
| positive regulation of apoptotic process involved in mammary gland involution | biological_process | VDR, BAX |
| positive regulation of apoptotic signaling pathway | biological_process | PTEN, TP63 |
| positive regulation of appetite | biological_process | OPRM1, GHRL, NPY |
| positive regulation of arachidonic acid secretion | biological_process | MIF |
| positive regulation of astrocyte chemotaxis | biological_process | CCR2 |
| positive regulation of astrocyte differentiation | biological_process | NOTCH1, IL6ST, LIF, IL1B, ID2 |
| positive regulation of ATP biosynthetic process | biological_process | STAT3 |
| positive regulation of attachment of spindle microtubules to kinetochore | biological_process | CCNB1 |
| positive regulation of autophagy | biological_process | IFNG, HIF1A, FOXO1, AGER, PIM2, DCN |
| positive regulation of axon extension | biological_process | GSK3B, L1CAM, FN1, NRG1, LIMK1 |
| positive regulation of axon extension involved in axon guidance | biological_process | VEGFA, CXCL12, NRP1 |
| positive regulation of axon regeneration | biological_process | BRAF, CNTF |
| positive regulation of axonogenesis | biological_process | BRAF, NGF, NTRK2, RHOA |
| positive regulation of B cell activation | biological_process | IL4, IL6, NOD2 |
| positive regulation of B cell apoptotic process | biological_process | IL10, BAX |
| positive regulation of B cell differentiation | biological_process | MMP14, PRDM1 |
| positive regulation of B cell proliferation | biological_process | BCL2, BCL6, MIF, CDKN1A, CD40, IL13, TLR4, ADA, CD74, IL4, IL5, TNFSF13B, IRS2, IL2 |
| positive regulation of B cell receptor signaling pathway | biological_process | PRKCB |
| positive regulation of behavioral fear response | biological_process | GJA1, CRH, UCN |
| positive regulation of beta-amyloid formation | biological_process | CLU, APOE |
| positive regulation of binding | biological_process | PON1, ENO1, ANXA2 |
| positive regulation of blood circulation | biological_process | PTGER3 |
| positive regulation of blood coagulation | biological_process | F2R, CD36, SERPINE1, THBS1, HPSE, NFE2L2 |
| positive regulation of blood microparticle formation | biological_process | CD36, TNF |
| positive regulation of blood pressure | biological_process | TACR1, OXTR, ADIPOQ, ID2, CRHR2 |
| positive regulation of blood vessel endothelial cell migration | biological_process | FGF2, VEGFA, AKT1, VEGFC, TGFB1, HSPB1, THBS1, ANGPT1 |
| positive regulation of BMP signaling pathway | biological_process | BMP4, NOTCH1, ENG, CYR61, HES5, SMAD2, SMAD4, GATA6 |
| positive regulation of bone mineralization | biological_process | BMP4, PLA2G4A, BMP6, TGFB1, BMPR1B, SMAD3, WNT4 |
| positive regulation of bone mineralization involved in bone maturation | biological_process | LTF |
| positive regulation of bone resorption | biological_process | PTGER4, SPP1, CA2, FSHB, ADAM8 |
| positive regulation of brain-derived neurotrophic factor receptor signaling pathway | biological_process | BDNF |
| positive regulation of branching involved in lung morphogenesis | biological_process | BMP4, CTNNB1 |
| positive regulation of branching involved in ureteric bud morphogenesis | biological_process | VEGFA, AGTR2, GREM1, TGFB1, PAX2 |
| positive regulation of brown fat cell differentiation | biological_process | PTGS2 |
| positive regulation of calcidiol 1-monooxygenase activity | biological_process | IFNG, TNF, IL1B |
| positive regulation of calcineurin-NFAT signaling cascade | biological_process | ERBB3, IGF1, NRG1 |
| positive regulation of calcitonin secretion | biological_process | PTGER4 |
| positive regulation of calcium ion import | biological_process | LGALS3, CCL3, CCL2, CXCL12, CRH, UCN, STC1 |
| positive regulation of calcium ion transport | biological_process | F2R, CCL5, CCL3, CCR1, EDNRA, LPAR3 |
| positive regulation of calcium ion transport into cytosol | biological_process | BMP4, CD4, BAX, P2RX3 |
| positive regulation of calcium-dependent cell-cell adhesion | biological_process | KIFAP3 |
| positive regulation of calcium-independent cell-cell adhesion | biological_process | CX3CL1 |
| positive regulation of calcium-mediated signaling | biological_process | CCL3, CD4, ADA, P2RX3 |
| positive regulation of cAMP biosynthetic process | biological_process | PTGER4, ADM, PTGER3, GHRH, CRH, GPER1, UCN, CRHR2 |
| positive regulation of cAMP metabolic process | biological_process | CXCR3, CXCL10, CRHR2 |
| positive regulation of cAMP-dependent protein kinase activity | biological_process | ADIPOQ, SIRT1 |
| positive regulation of cAMP-mediated signaling | biological_process | OPRM1, CXCR3, LHCGR, CXCL10 |
| positive regulation of canonical Wnt signaling pathway | biological_process | SRC, YAP1, FGFR2, NFKB1, WNT2, PSMD9, LGR5, WNT7A, PSMD10, WNT1, DLX5, WNT4, SFRP4 |
| positive regulation of cardiac muscle cell differentiation | biological_process | GREM1, TGFB1, NRG1 |
| positive regulation of cardiac muscle cell proliferation | biological_process | FGFR1, FGF2, FGFR2, CCNB1, WNT2, NOTCH1, NRG1, GATA6 |
| positive regulation of cardiac muscle contraction | biological_process | HSP90AA1, UCN |
| positive regulation of cardiac muscle fiber development | biological_process | BMP4 |
| positive regulation of cardiac muscle hypertrophy | biological_process | IL6ST, IGF1, EDN1 |
| positive regulation of cardiac vascular smooth muscle cell differentiation | biological_process | GPER1 |
| positive regulation of cardioblast differentiation | biological_process | TGFB2, GATA6 |
| positive regulation of cardiolipin metabolic process | biological_process | STOML2 |
| positive regulation of cartilage development | biological_process | BMP4, WNT5A, BMPR1B, CYR61 |
| positive regulation of catagen | biological_process | TGFB2 |
| positive regulation of catalytic activity | biological_process | BCL2, IGFBP3, CASP3, CXCL1, SOD1, APOA2, IGF2, PSAP, ATP7A, DNMT3L, MMP24 |
| positive regulation of catenin import into nucleus | biological_process | EGFR, EGF, POU5F1 |
| positive regulation of CD24 biosynthetic process | biological_process | PLCB1 |
| positive regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | CD83 |
| positive regulation of CD4-positive, alpha-beta T cell proliferation | biological_process | LGALS9 |
| positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | biological_process | FOXP3 |
| positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response | biological_process | IFNG, LGALS9 |
| positive regulation of CD8-positive, alpha-beta T cell extravasation | biological_process | CCR2 |
| positive regulation of CD8-positive, alpha-beta T cell proliferation | biological_process | HLA-E |
| positive regulation of cell adhesion | biological_process | SRC, VEGFA, CCL5, IL12B, PTGER4, ITGA2, SAA1, CCL2, SELP, IL12A, CXCL12, ITGAV, IFNG, TNF, ERBB2, C1QBP, NRG1, ADAM8, CX3CL1, ANGPT1, CCR7 |
| positive regulation of cell adhesion mediated by integrin | biological_process | CCL21, TGFB2 |
| positive regulation of cell adhesion molecule production | biological_process | IL1B |
| positive regulation of cell communication by chemical coupling | biological_process | GJA1 |
| positive regulation of cell cycle | biological_process | FGFR1, CCND1, FGFR2, CCNB1, SLC6A4, CDKN1B, BCL2L11, TGFB2 |
| positive regulation of cell cycle arrest | biological_process | HMGA2, BRCA1, TGFB1, TP53, ID2, CDKN2A, GATA6 |
| positive regulation of cell cycle G1/S phase transition | biological_process | TP63 |
| positive regulation of cell death | biological_process | BMP4, CDKN1B, CDKN1A, FAS, MTOR, PTGS2, AKR1C3, BCL2L11, IL1B, HP, CRH, DNMT3A, NOD1 |
| positive regulation of cell development | biological_process | HOXA11 |
| positive regulation of cell differentiation | biological_process | GATA3, BMP4, CLU, AR, SOX2, JUN, BMPR1B, CYR61, SOCS3 |
| positive regulation of cell division | biological_process | FGF2, VEGFA, FGFR2, PTN, MDK, VEGFC, FGF1, TGFB1, IL1A, PDGFA, FIGF, IL1B, IGF2, CAT, TGFB2, YBX1, PROK1 |
| positive regulation of cell fate specification | biological_process | FGF2 |
| positive regulation of cell growth | biological_process | BCL2, AKT1, IGFBP1, IL9, MMP14, IGF1, EGFR, ERBB2, SGK1, PSMD10, CDC42, TGFB2, NRG1, ADAM17, UCN, IL2, CXCL16 |
| positive regulation of cell growth involved in cardiac muscle cell development | biological_process | MTOR |
| positive regulation of cell migration | biological_process | VEGFA, BMP4, F2R, CCL5, MAPK1, PIK3R1, F3, KIT, CCL3, NOTCH1, KDR, CSF1, CCR1, PDGFRA, HGF, FLT1, TDGF1, MMP14, COL18A1, CXCL12, FN1, INSR, IGF1, ITGB1, EGFR, FGF1, ITGAV, TGFB1, ACTN4, IGF1R, CXCL10, PDGFA, CYR61, SNAI1, THBS1, PLAU, CGA, FSHB, EDN1, CSF1R, PTK2, SMAD3, PAK1, F2RL1, AIF1, ADAM17, AGER, GPER1, IRS2, CCL7, CX3CL1, SEMA3C, CXCL16, CCL11 |
| positive regulation of cell migration involved in sprouting angiogenesis | biological_process | VEGFA, PTGS2, CCR2 |
| positive regulation of cell motility | biological_process | EPCAM, CCL21, CLDN7, CSF1R, CCL19, TWIST1, CCR7 |
| positive regulation of cell projection organization | biological_process | ITGA2 |
| positive regulation of cell proliferation | biological_process | BCL2, FGFR1, YAP1, FGF2, CCND1, VEGFA, BMP4, PLA2G4A, F2R, WNT5A, MAPK1, FGFR2, CLU, KIT, LEP, SHC1, CTNNB1, EPCAM, PTGER4, AR, WNT2, CDKN1B, NOTCH1, KDR, FASLG, CSF1, FLT4, CXCR3, PDGFRA, AGTR2, IL6R, IL6ST, EDNRA, HGF, FLT1, STS, CNTF, CXCR2, KITLG, TDGF1, IL15, LIF, LIFR, IL9, IL11, PTN, TNC, FLT3, ADM, PTGS2, VEGFC, COL18A1, AKR1C3, CXCL5, PTGFR, CXCL12, AKR1C2, FN1, INSR, IGF1, GREM1, ITGB1, EGFR, JUN, FGF1, ITGAV, IFNG, TGFB1, IGF1R, TIMP1, MYC, CXCL10, PDGFA, BIRC5, WNT7A, FIGF, GDF9, CLDN7, EGF, PLAU, KRAS, CGA, FSHB, GHRH, IGF2, CSF2, WNT1, IL4, IL5, IL6, EDN1, CRH, CSF1R, PTEN, TGFB2, PTK2, HDAC2, RELA, NRG1, BCL2L1, NTRK2, HIF1A, HES5, S100A13, HDAC1, TNFSF13B, MST1R, SIRT1, ADAM17, GPER1, IL24, PAX2, IRS2, PROK1, IL2, NODAL, CLEC11A, TET1 |
| positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway | biological_process | VEGFA, PDGFRA |
| positive regulation of cell proliferation in bone marrow | biological_process | IL6 |
| positive regulation of cell proliferation involved in heart valve morphogenesis | biological_process | SMAD4 |
| positive regulation of cell size | biological_process | HSP90AA1, EDN1, HIF1A |
| positive regulation of cell-cell adhesion | biological_process | ITGA6, WNT5A, CCL2, SOX2, CCR2, FSTL3, SMAD7, NODAL |
| positive regulation of cell-cell adhesion mediated by cadherin | biological_process | WNT5A |
| positive regulation of cell-cell adhesion mediated by integrin | biological_process | CCL5, CXCL13 |
| positive regulation of cell-matrix adhesion | biological_process | GSK3B, CD36, CSF1, VEGFC, CCL25, CCL21, CCR7 |
| positive regulation of cell-substrate adhesion | biological_process | ITGA3, ALOX15, PTN, ITGB1, CYR61, AGR2, RAC1, SPOCK2, SMOC2 |
| positive regulation of cellular biosynthetic process | biological_process | CCL5 |
| positive regulation of cellular component movement | biological_process | VEGFA, BCL6, STMN1, ACTN4, ADAM17 |
| positive regulation of cellular extravasation | biological_process | CCL2, ICAM1, ADAM8 |
| positive regulation of cellular metabolic process | biological_process | ACLY |
| positive regulation of cellular pH reduction | biological_process | CA2 |
| positive regulation of cellular protein metabolic process | biological_process | INHBA, AKT1, CSF1, AGTR1, TGFB1, ADIPOQ |
| positive regulation of cellular response to X-ray | biological_process | HMGA2 |
| positive regulation of cellular senescence | biological_process | HMGA2, HMGA1, CDKN2A, SIRT1 |
| positive regulation of ceramide biosynthetic process | biological_process | TNFRSF1A, TNF, CYR61, SMPD3 |
| positive regulation of cerebellar granule cell precursor proliferation | biological_process | EGF |
| positive regulation of cGMP biosynthetic process | biological_process | APOE |
| positive regulation of cGMP metabolic process | biological_process | WNT5A |
| positive regulation of chemokine (C-C motif) ligand 2 secretion | biological_process | POSTN |
| positive regulation of chemokine (C-X-C motif) ligand 2 production | biological_process | MIF, TNF, CD74 |
| positive regulation of chemokine biosynthetic process | biological_process | WNT5A, HMOX1, IFNG, TNF, TLR3, IL1B, IL4 |
| positive regulation of chemokine production | biological_process | IL6R, TNF, TLR2, TLR4, TLR3, IL6, HIF1A, TLR9, ADAM17 |
| positive regulation of chemokine secretion | biological_process | IL33, C5, CSF1R, IL1RL1 |
| positive regulation of chemokine-mediated signaling pathway | biological_process | EDN1, HIF1A |
| positive regulation of chemokinesis | biological_process | PTGER4 |
| positive regulation of chemotaxis | biological_process | CXCR3, FN1, TGFB1, CCL21, THBS1, F2RL1, CCL19, RARRES2 |
| positive regulation of cholangiocyte proliferation | biological_process | MTOR |
| positive regulation of cholesterol biosynthetic process | biological_process | FGF1 |
| positive regulation of cholesterol efflux | biological_process | PON1, APOE, ADIPOQ, SIRT1 |
| positive regulation of cholesterol esterification | biological_process | AGTR1, APOA1, APOA2, APOE |
| positive regulation of cholesterol storage | biological_process | CD36, SCARB1 |
| positive regulation of chondrocyte differentiation | biological_process | BMP6, HOXA11, BMPR1B, SMAD3, RELA, IHH |
| positive regulation of chondrocyte proliferation | biological_process | LTF |
| positive regulation of chromatin binding | biological_process | KAT2B |
| positive regulation of chromatin silencing | biological_process | SIRT1 |
| positive regulation of chromatin-mediated maintenance of transcription | biological_process | CTNNB1 |
| positive regulation of chronic inflammatory response | biological_process | IDO1 |
| positive regulation of chronic inflammatory response to antigenic stimulus | biological_process | TNF, LTA |
| positive regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | PTGER4, PTGER3, GHRL |
| positive regulation of circadian sleep/wake cycle, REM sleep | biological_process | GHRH |
| positive regulation of circadian sleep/wake cycle, wakefulness | biological_process | CRH |
| positive regulation of collagen binding | biological_process | ITGA2 |
| positive regulation of collagen biosynthetic process | biological_process | BMP4, F2R, ITGA2, CCL2, TGFB1, HDAC2, UCN, WNT4 |
| positive regulation of collagen metabolic process | biological_process | RETN |
| positive regulation of collateral sprouting | biological_process | BDNF, LPAR3 |
| positive regulation of colon smooth muscle contraction | biological_process | PTGER3 |
| positive regulation of connective tissue growth factor production | biological_process | IL13 |
| positive regulation of corticosterone secretion | biological_process | CRH |
| positive regulation of corticotropin secretion | biological_process | LIF, CRH, GHRL, UCN |
| positive regulation of cortisol biosynthetic process | biological_process | WNT4 |
| positive regulation of cortisol secretion | biological_process | CRH, GHRL |
| positive regulation of CREB transcription factor activity | biological_process | VEGFA |
| positive regulation of cyclic nucleotide-gated ion channel activity | biological_process | CFTR |
| positive regulation of cyclin-dependent protein kinase activity | biological_process | CDKN1A |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological_process | SRC, CCND1, CDKN1B, PSMD10 |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological_process | AKT1, EGFR, ADAM17 |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | F2R, HMGB1, TNFSF10, FAS, TNF, MYC, PDCD6, CYR61, BCL2L11, FOXL2, SIRT1, NOD1, GPER1, DAPK1, NODAL |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological_process | LGALS9 |
| positive regulation of cytokine activity | biological_process | NRP1 |
| positive regulation of cytokine production | biological_process | GATA3, WNT5A, LEP, SOD1, TNF, TLR3 |
| positive regulation of cytokine production involved in inflammatory response | biological_process | NOD2, IL17A, IL17F |
| positive regulation of cytokine secretion | biological_process | SRC, IL10, MIF, PTGER4, CASP1, AGTR2, SAA1, IL1A, TNF, CADM1 |
| positive regulation of cytokine secretion involved in immune response | biological_process | WNT5A, F2RL1 |
| positive regulation of cytokine-mediated signaling pathway | biological_process | AXL, CD74, GAS6 |
| positive regulation of cytokinesis | biological_process | DRD2, SSTR5, CDC42, RHOA |
| positive regulation of cytolysis | biological_process | LILRB1 |
| positive regulation of cytosolic calcium ion concentration | biological_process | F2R, HMGB1, GJA1, CD36, OPRM1, CCR1, CCR5, CXCR3, PDGFRA, AGTR1, EDNRA, GATA2, SAA1, TACR1, OXTR, ADM, CCR2, PTGER3, CCR9, ESR1, CXCL13, IL1B, EDN1, CXCR4, F2RL1, GHRL, GPER1, IL2, KISS1, HRH4, LPAR3, CCR7, CCR8 |
| positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | biological_process | F2R, DRD2, AGTR1, EDNRA, EDN1, KISS1, LPAR3 |
| positive regulation of defense response to virus by host | biological_process | IL12B, ANXA5, MSTN, CLDN7, IL4, IL23A, LILRB1 |
| positive regulation of dendrite development | biological_process | EZH2 |
| positive regulation of dendrite morphogenesis | biological_process | SGK1 |
| positive regulation of dendritic cell antigen processing and presentation | biological_process | CCL21, CD74, NOD2, CCL19, NOD1, CCR7 |
| positive regulation of dendritic cell apoptotic process | biological_process | LGALS9 |
| positive regulation of dendritic cell chemotaxis | biological_process | IL12A, LGALS9, C1QBP, GAS6, CCR7 |
| positive regulation of dendritic cell dendrite assembly | biological_process | CCL19 |
| positive regulation of dendritic cell differentiation | biological_process | HMGB1, LGALS3, LGALS1, LGALS9, AGER |
| positive regulation of dendritic spine development | biological_process | MTOR, APOE, NRG1, IL2 |
| positive regulation of dendritic spine maintenance | biological_process | APOE |
| positive regulation of deoxyribonuclease activity | biological_process | PCNA |
| positive regulation of dermatome development | biological_process | WNT1, WNT4 |
| positive regulation of determination of dorsal identity | biological_process | CTNNB1 |
| positive regulation of developmental growth | biological_process | LEP, INSR, C3, AGR2, PLCB1 |
| positive regulation of developmental pigmentation | biological_process | BCL2, BAX |
| positive regulation of digestive system process | biological_process | CRH |
| positive regulation of dipeptide transmembrane transport | biological_process | CA2 |
| positive regulation of DNA binding | biological_process | TXN, HMGB1, MMP9, NME1, ITGA2, IGF1, EGF, PLAUR |
| positive regulation of DNA biosynthetic process | biological_process | GSK3B, SRC, HGF, MYC |
| positive regulation of DNA damage response, signal transduction by p53 class mediator | biological_process | ATM, CDKN2A |
| positive regulation of DNA ligation | biological_process | HMGB1 |
| positive regulation of DNA repair | biological_process | H2AFX, PCNA, APEX1, BRCA1, EGFR, SIRT1 |
| positive regulation of DNA replication | biological_process | PCNA, SHC1, PDGFRA, KITLG, INSR, IGF1, EGFR, JUN, IGF1R, PDGFA, CSF2, IL6, CDC42, RAC1, UCN |
| positive regulation of DNA-dependent DNA replication | biological_process | BMP4, BMP6 |
| positive regulation of DNA-templated transcription, initiation | biological_process | CTNNB1, JUN, TWIST1 |
| positive regulation of dopamine biosynthetic process | biological_process | PARK7 |
| positive regulation of dopamine secretion | biological_process | CXCL12 |
| positive regulation of dopamine uptake involved in synaptic transmission | biological_process | DRD2 |
| positive regulation of eating behavior | biological_process | MTOR |
| positive regulation of embryonic development | biological_process | PLCB1 |
| positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation | biological_process | TWIST1 |
| positive regulation of endocytosis | biological_process | WNT5A, ITGB1, CCL19 |
| positive regulation of endodeoxyribonuclease activity | biological_process | AKT1 |
| positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological_process | BCL2L11, SIRT1 |
| positive regulation of endoplasmic reticulum unfolded protein response | biological_process | PIK3R1, BAX |
| positive regulation of endothelial cell apoptotic process | biological_process | BMP4, CD40LG, FASLG, CD40, COL18A1, AKR1C3, THBS1, AGER, GPER1 |
| positive regulation of endothelial cell chemotaxis | biological_process | MET, HSPB1 |
| positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway | biological_process | VEGFA, KDR, HSPB1 |
| positive regulation of endothelial cell chemotaxis to fibroblast growth factor | biological_process | FGFR1, FGF2 |
| positive regulation of endothelial cell differentiation | biological_process | BMP4, CTNNB1, NOTCH1, BMP6 |
| positive regulation of endothelial cell migration | biological_process | GATA3, VEGFA, BMP4, WNT5A, KDR, FLT4, SPARC, TDGF1, ITGB3, FGF1, PDCD6, WNT7A, NRP1, THBS1, NRP2, EDN1, FOXP1, TEK, SCARB1, ANGPT1 |
| positive regulation of endothelial cell proliferation | biological_process | FGF2, VEGFA, BMP4, WNT5A, F3, AKT1, WNT2, KDR, FLT4, CCL2, BMP6, ARNT, MTOR, CXCL12, ITGB3, JUN, ANG, PDCD6, NRP1, NRP2, HIF1A, TEK, SIRT1, CCL11 |
| positive regulation of energy homeostasis | biological_process | GHRL |
| positive regulation of eosinophil chemotaxis | biological_process | IL4 |
| positive regulation of eosinophil degranulation | biological_process | F2RL1 |
| positive regulation of eosinophil differentiation | biological_process | IL5 |
| positive regulation of eosinophil migration | biological_process | ADAM8 |
| positive regulation of epidermal cell differentiation | biological_process | BMP4, SFRP4 |
| positive regulation of epidermal growth factor receptor signaling pathway | biological_process | MMP9, AKT1, FASLG, ESR1, AGR2, PLAUR, ESR2, GPER1 |
| positive regulation of epidermal growth factor-activated receptor activity | biological_process | EGF, ADAM17 |
| positive regulation of epithelial cell apoptotic process | biological_process | TIA1 |
| positive regulation of epithelial cell differentiation | biological_process | CTNNB1 |
| positive regulation of epithelial cell migration | biological_process | SRC, ITGA3, ITGA2, TACR1, JUN, IFNG, TGFB2, HIF1A |
| positive regulation of epithelial cell proliferation | biological_process | VEGFA, BMP4, WNT5A, CCL5, FGFR2, NOTCH1, NME1, ID1, TACR1, BMP6, VEGFC, MMP12, ESR1, IGF1, EGFR, FGF1, TGFB1, MYC, ERBB2, IL6, NOD2, TWIST1, PAX2, DLX5, IHH, HTRA1, NODAL, LAMC1 |
| positive regulation of epithelial cell proliferation involved in lung morphogenesis | biological_process | FGFR2, WNT2, CDC42 |
| positive regulation of epithelial cell proliferation involved in prostate gland development | biological_process | CTNNB1 |
| positive regulation of epithelial cell proliferation involved in wound healing | biological_process | MMP12, WNT7A |
| positive regulation of epithelial to mesenchymal transition | biological_process | CTNNB1, NOTCH1, TGFB1, SNAI1, TGFB1I1, TGFB2, HDAC2, SMAD3, SMAD2, EZH2, SMAD4, AGER, TWIST1, OLFM1 |
| positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | TGFB2 |
| positive regulation of ER-associated ubiquitin-dependent protein catabolic process | biological_process | NFE2L2 |
| positive regulation of ERK1 and ERK2 cascade | biological_process | SRC, FGF2, VEGFA, FSHR, BMP4, F2R, CCL5, FGFR2, HMGB1, CD36, ALOX15, CHI3L1, OPRM1, MIF, CCL3, DRD2, KDR, CCR1, FLT4, BRAF, PDGFRA, EDNRA, CD44, CCL2, PLA2G2A, ESR1, EGFR, JUN, FGF1, FGA, TNF, PDGFA, C3, LGALS9, TLR4, CCL25, CCL21, CCL22, NRP1, CCL16, SPRY2, IL1B, ICAM1, CD74, IL6, CSF1R, PTEN, GAS6, TEK, F2RL1, NOD2, ESR2, CCL19, NOD1, PTPN22, GPER1, CCL7, CX3CL1, ANGPT1, CCL17, NODAL, CCR7, CCL11 |
| positive regulation of erythrocyte aggregation | biological_process | LGALS1 |
| positive regulation of erythrocyte differentiation | biological_process | INHBA, GATA2, ARNT, HIF1A, ID2 |
| positive regulation of establishment of endothelial barrier | biological_process | CLDN5 |
| positive regulation of establishment of protein localization to plasma membrane | biological_process | ITGA3, PIK3R1, AKT1, ITGB1, IFNG, AGR2, GPER1 |
| positive regulation of excitatory postsynaptic potential | biological_process | GSK3B, WNT7A, PTEN |
| positive regulation of excitatory synapse assembly | biological_process | WNT7A |
| positive regulation of execution phase of apoptosis | biological_process | CXCR3, TP53 |
| positive regulation of exit from mitosis | biological_process | TGFB1, BIRC5 |
| positive regulation of exocytosis | biological_process | CFTR, FGA |
| positive regulation of exosomal secretion | biological_process | SDC4, SDC1, IFNG, SMPD3 |
| positive regulation of extracellular exosome assembly | biological_process | SDC4, SDC1 |
| positive regulation of extracellular matrix assembly | biological_process | TGFB1, SMAD3 |
| positive regulation of extracellular matrix constituent secretion | biological_process | CPB2 |
| positive regulation of extracellular matrix disassembly | biological_process | TGFB2 |
| positive regulation of extrinsic apoptotic signaling pathway | biological_process | TNFSF10, AGTR2, G0S2, FAS, GPER1 |
| positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological_process | INHBA, CTNNA1, FAS, TGFB2, BAX |
| positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological_process | BMPR1B, THBS1 |
| positive regulation of fat cell apoptotic process | biological_process | LEP |
| positive regulation of fat cell differentiation | biological_process | PPARG, AKT1, IGF1, RARRES2, ID2, SULT1E1 |
| positive regulation of fatty acid beta-oxidation | biological_process | PPARA, TWIST1, IRS2 |
| positive regulation of fatty acid biosynthetic process | biological_process | APOA1 |
| positive regulation of fatty acid metabolic process | biological_process | ADIPOQ |
| positive regulation of fatty acid oxidation | biological_process | PPARG, PPARA |
| positive regulation of fever generation | biological_process | PLA2G4A, CCL5, PTGS2, CCR2, PTGER3, TNF, IL1B |
| positive regulation of fibroblast apoptotic process | biological_process | BCL2L11, TP63 |
| positive regulation of fibroblast growth factor production | biological_process | PTGS2 |
| positive regulation of fibroblast growth factor receptor signaling pathway | biological_process | CTNNB1 |
| positive regulation of fibroblast migration | biological_process | AKT1, TGFB1, THBS1, AGER |
| positive regulation of fibroblast proliferation | biological_process | WNT5A, FBLN1, MIF, CCNB1, WNT2, CDKN1A, PDGFRA, FN1, ESR1, IGF1, EGFR, JUN, TGFB1, S100A6, MYC, PDGFA, ANXA2, CD74, WNT1, GAS6, AGER |
| positive regulation of fibronectin-dependent thymocyte migration | biological_process | ADAM8 |
| positive regulation of filopodium assembly | biological_process | CCL21, CCR7 |
| positive regulation of focal adhesion assembly | biological_process | VEGFA, KDR, SDC4, RAC1, SMAD3, TEK, WNT4 |
| positive regulation of follicle-stimulating hormone secretion | biological_process | INHBA, LEP, INHA, FOXL2, SMAD4 |
| positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity | biological_process | IFNG |
| positive regulation of fructose 1,6-bisphosphate metabolic process | biological_process | IFNG |
| positive regulation of G-protein coupled receptor protein signaling pathway | biological_process | DRD2, C3, GPER1 |
| positive regulation of G0 to G1 transition | biological_process | SOX15 |
| positive regulation of G1/S transition of mitotic cell cycle | biological_process | APEX1, ANXA1, CYP1A1, PLCB1, AIF1 |
| positive regulation of G2/M transition of mitotic cell cycle | biological_process | CCND1 |
| positive regulation of gamma-delta T cell activation | biological_process | NOD2 |
| positive regulation of gamma-delta T cell activation involved in immune response | biological_process | LILRB1 |
| positive regulation of gastric mucosal blood circulation | biological_process | PTGER3 |
| positive regulation of gene expression | biological_process | SRC, GATA3, INHBA, VEGFA, STAT3, BMP4, DNMT1, HMGA2, ITGA3, CCL5, FBLN1, GJA1, KIT, VIM, CTNNB1, BRCA1, PTGER4, CCL3, SLC6A4, NFKB1, AR, ID1, CSF1, VDR, BRAF, CNTF, LIF, HNF1B, CDH3, TNC, MTOR, CCR2, PTGFR, PTGER3, STAR, FN1, IFNG, TGFB1, IL1A, NGF, TP53, TNF, LGALS9, TLR2, TLR4, CRP, WNT7A, TLR3, SPRY2, PRDM1, IL1B, IL33, AGR2, KRAS, AMH, CSF2, IL6, CRH, CDC42, TGFB2, SMAD3, PARK7, NTRK2, HIF1A, GAS6, SMAD2, TLR9, NFE2L2, IL18, FOXP3, ID2, PTPN22, AGER, TWIST1, GPER1, DNMT3B, NR0B2, UCN, DLL4, CRHR2, SFRP4, OLFM1, MAF, LILRB1, PIAS3 |
| positive regulation of gene expression, epigenetic | biological_process | ACTB, KAT2B, HIST2H3A |
| positive regulation of gene silencing by miRNA | biological_process | STAT3 |
| positive regulation of germinal center formation | biological_process | ADA |
| positive regulation of glial cell differentiation | biological_process | NOTCH1, IL1B |
| positive regulation of glial cell proliferation | biological_process | MTOR, LTA |
| positive regulation of glial cell-derived neurotrophic factor secretion | biological_process | DRD2 |
| positive regulation of glomerular filtration | biological_process | GJA1, GAS6, F2RL1 |
| positive regulation of glomerular metanephric mesangial cell proliferation | biological_process | EGR1 |
| positive regulation of gluconeogenesis | biological_process | FOXO1, PPARA |
| positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter | biological_process | KAT2B |
| positive regulation of glucose import | biological_process | PIK3R1, AKT1, INSR, IGF1, ADIPOQ, NFE2L2, IRS2, ADIPOR2 |
| positive regulation of glucose import in response to insulin stimulus | biological_process | PIK3R1, RARRES2 |
| positive regulation of glucose metabolic process | biological_process | SRC, AKT1, IRS2 |
| positive regulation of glucose transport | biological_process | C3 |
| positive regulation of glutamate secretion | biological_process | DPYSL2 |
| positive regulation of glutathione biosynthetic process | biological_process | NFE2L2 |
| positive regulation of glycogen (starch) synthase activity | biological_process | IGF2, ADIPOQ |
| positive regulation of glycogen biosynthetic process | biological_process | AKT1, INSR, IGF1, IGF2, IRS2 |
| positive regulation of glycogen catabolic process | biological_process | HMGB1 |
| positive regulation of glycolytic process | biological_process | ARNT, INSR, IGF1, HIF1A |
| positive regulation of glycoprotein biosynthetic process | biological_process | INSR, IGF1, CCL21, CCL19 |
| positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation | biological_process | CCR7 |
| positive regulation of granulocyte macrophage colony-stimulating factor production | biological_process | IL12B, PAEP, IL1B, TLR9, IL18, IL23A |
| positive regulation of granulosa cell proliferation | biological_process | MTOR |
| positive regulation of growth factor dependent skeletal muscle satellite cell proliferation | biological_process | STAT3 |
| positive regulation of growth hormone receptor signaling pathway | biological_process | GHRL |
| positive regulation of growth hormone secretion | biological_process | DRD2, GHRH, GHRL, KISS1 |
| positive regulation of GTP binding | biological_process | TGFB2 |
| positive regulation of GTPase activity | biological_process | GSK3B, FGFR1, ITGA6, FGF2, WNT5A, CCL5, FGFR2, KIT, SHC1, CCL3, ERBB3, CSF2RB, CD40, PDGFRA, JAK1, KITLG, CCL2, NCAM1, IL2RB, ITGB1, EGFR, JUN, FGF1, A2M, PDGFA, ERBB2, CCL25, FYN, CCL22, CCL16, KALRN, EGF, IL2RA, ICAM1, CSF2, IL5, PTK2, NRG1, PLCB1, TEK, CCL19, ERRFI1, EZH2, IRS2, CCL7, CX3CL1, WNT4, IL2, ANGPT1, CCL17, CCL11 |
| positive regulation of guanylate cyclase activity | biological_process | NOS2, NOS3 |
| positive regulation of hair cycle | biological_process | TERT |
| positive regulation of hair follicle cell proliferation | biological_process | CDC42 |
| positive regulation of hair follicle development | biological_process | FST, TNF, HPSE |
| positive regulation of heart contraction | biological_process | TGFB2 |
| positive regulation of heart growth | biological_process | WT1 |
| positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway | biological_process | DKK1 |
| positive regulation of heart rate | biological_process | ADM, ADA, EDN1, CRHR2 |
| positive regulation of helicase activity | biological_process | MSH2, MSH6 |
| positive regulation of hematopoietic stem cell migration | biological_process | CCR2 |
| positive regulation of hematopoietic stem cell proliferation | biological_process | KITLG |
| positive regulation of heparan sulfate proteoglycan biosynthetic process | biological_process | CTNNB1 |
| positive regulation of hepatic stellate cell activation | biological_process | LEP |
| positive regulation of hepatocyte differentiation | biological_process | BMP4 |
| positive regulation of hepatocyte proliferation | biological_process | PTN |
| positive regulation of heterotypic cell-cell adhesion | biological_process | ALOX15, CD44, FGA, TNF, IL1B |
| positive regulation of histone acetylation | biological_process | BRCA1, TGFB1, IL1B, FOXP3 |
| positive regulation of histone deacetylase activity | biological_process | VEGFA |
| positive regulation of histone deacetylation | biological_process | BCL6, TGFB1, TP53 |
| positive regulation of histone H3-K14 acetylation | biological_process | GATA3, KAT2B |
| positive regulation of histone H3-K27 acetylation | biological_process | LIF |
| positive regulation of histone H3-K4 methylation | biological_process | DNMT1, CTNNB1, BRCA1, SMAD4, DNMT3B |
| positive regulation of histone H3-K9 acetylation | biological_process | GATA3, BRCA1, KAT2B, SMAD4 |
| positive regulation of histone H3-K9 methylation | biological_process | BRCA1, SIRT1 |
| positive regulation of histone H4 acetylation | biological_process | MUC1 |
| positive regulation of histone H4-K16 acetylation | biological_process | BRCA1 |
| positive regulation of histone H4-K20 methylation | biological_process | BRCA1 |
| positive regulation of histone methylation | biological_process | TET1 |
| positive regulation of histone phosphorylation | biological_process | CCNB1, IL1B, ATM |
| positive regulation of homocysteine metabolic process | biological_process | COMT |
| positive regulation of homotypic cell-cell adhesion | biological_process | CCL5 |
| positive regulation of hormone biosynthetic process | biological_process | ARNT, HIF1A |
| positive regulation of hormone secretion | biological_process | TACR1, GHRH, EDN1, KISS1R |
| positive regulation of humoral immune response | biological_process | CCR7 |
| positive regulation of humoral immune response mediated by circulating immunoglobulin | biological_process | TNF, LTA, HPX, FCER2 |
| positive regulation of hyaluronan biosynthetic process | biological_process | PTGER4, NFKB1, EGF |
| positive regulation of hydrolase activity | biological_process | APOA1 |
| positive regulation of hypersensitivity | biological_process | CCR7 |
| positive regulation of I-kappaB kinase/NF-kappaB signaling | biological_process | F2R, TNFRSF1A, GJA1, CD36, CTNNB1, CASP1, TNFSF10, FASLG, CD40, LGALS1, HMOX1, RHOC, MAP3K7, PRKCB, IL1A, LTF, TNF, LGALS9, TLR4, FYN, CCDC22, CCL21, TLR3, IL1B, RELA, S100A13, F2RL1, ADIPOQ, TLR9, NOD2, CCL19, NOD1, PIM2, CCR7, RHOA |
| positive regulation of immature T cell proliferation in thymus | biological_process | IL1B, FOXP3 |
| positive regulation of immune complex clearance by monocytes and macrophages | biological_process | CCL2, CCR2 |
| positive regulation of immune response | biological_process | IL15, FCER1G, CTSG, TGFB2 |
| positive regulation of immunoglobulin production | biological_process | IL13, HPX, IL4 |
| positive regulation of immunoglobulin secretion | biological_process | HLA-E, IL33, IL5, IL6, IL2 |
| positive regulation of immunological synapse formation | biological_process | CCR7 |
| positive regulation of inflammatory response | biological_process | PLA2G4A, WNT5A, TNFRSF1A, CCL5, IL12B, PTGER4, CCL3, AGTR1, EDNRA, ITGA2, CCL2, PLA2G2A, IL15, CCR2, CLOCK, TLR2, TLR4, TLR3, CCL16, SERPINE1, IL33, TLR9, IL18, AGER, ADAM8, IL1RL1, IL23A, CCL7, CX3CL1, IL2, CCL11 |
| positive regulation of inhibitory G-protein coupled receptor phosphorylation | biological_process | PTGER3 |
| positive regulation of innate immune response | biological_process | CCL5, HMGB1, MMP2 |
| positive regulation of inositol trisphosphate biosynthetic process | biological_process | LHCGR, GPER1 |
| positive regulation of insulin receptor signaling pathway | biological_process | SRC, LEP, IGF2, SIRT1, ADIPOR1 |
| positive regulation of insulin secretion | biological_process | GJA1, PSMD9, GHRL, GPER1, NR0B2, IRS2 |
| positive regulation of insulin secretion involved in cellular response to glucose stimulus | biological_process | CFTR, HLA-DRB1, CRH, HIF1A |
| positive regulation of insulin-like growth factor receptor signaling pathway | biological_process | IGFBP3, IGFBP5, CDH3, IGFBP4, IGF1, GHRH, WNT1 |
| positive regulation of integrin activation | biological_process | SRC, CXCL13 |
| positive regulation of integrin biosynthetic process | biological_process | AR, TGFB2 |
| positive regulation of interferon-alpha biosynthetic process | biological_process | TLR3, TLR9 |
| positive regulation of interferon-alpha production | biological_process | HSPD1, HMGB1, TLR4 |
| positive regulation of interferon-beta biosynthetic process | biological_process | TLR4, TLR3, TLR9 |
| positive regulation of interferon-beta production | biological_process | HMGB1, TLR2, TLR4, TLR3, TLR9 |
| positive regulation of interferon-gamma biosynthetic process | biological_process | IL12B, TLR3, TLR9, IL27 |
| positive regulation of interferon-gamma production | biological_process | HSPD1, WNT5A, IL12B, IL12A, CCR2, TNF, TLR4, IL1B, LTA, HLA-DPB1, IL18, IL23A, IL2, KLRK1 |
| positive regulation of interferon-gamma secretion | biological_process | LGALS9, PTPN22 |
| positive regulation of interferon-gamma-mediated signaling pathway | biological_process | HPX |
| positive regulation of interleukin-1 alpha secretion | biological_process | CASP1 |
| positive regulation of interleukin-1 beta production | biological_process | HSPB1, SMAD3, NOD2, NOD1 |
| positive regulation of interleukin-1 beta secretion | biological_process | WNT5A, HMGB1, CCL3, CASP1, CCR2, IFNG, LGALS9, NOD2, CCL19 |
| positive regulation of interleukin-1 production | biological_process | TLR4, HDAC2 |
| positive regulation of interleukin-1 secretion | biological_process | HMGB1, SAA1 |
| positive regulation of interleukin-10 production | biological_process | HSPD1, CD40LG, HMGB1, IL12B, HGF, FCER1G, TLR4, IL4, TLR9, NOD2, IL23A, IL20RB, CD83 |
| positive regulation of interleukin-10 secretion | biological_process | PTGER4, LGALS9 |
| positive regulation of interleukin-12 biosynthetic process | biological_process | IFNG, TLR4, RELA |
| positive regulation of interleukin-12 production | biological_process | HSPD1, CD40LG, HMGB1, CD36, IL12B, CD40, IDO1, HLA-G, IFNG, TLR2, TLR4, TLR3, PLCB1, TLR9, CCL19, AGER, IL23A, CCR7 |
| positive regulation of interleukin-12 secretion | biological_process | LGALS9 |
| positive regulation of interleukin-13 production | biological_process | GATA3, HLA-E, IL33, IL4 |
| positive regulation of interleukin-13 secretion | biological_process | GATA3, PAEP, LGALS9 |
| positive regulation of interleukin-17 production | biological_process | IL12B, IL15, TGFB1, NOD2, IL18, IL23A, IL2 |
| positive regulation of interleukin-18 production | biological_process | TLR2, TLR9 |
| positive regulation of interleukin-2 biosynthetic process | biological_process | IL1A, CD4, IL1B |
| positive regulation of interleukin-2 production | biological_process | CCR2, ANXA1, MAP3K7, CD83 |
| positive regulation of interleukin-23 production | biological_process | IFNG, CSF2, IL17A |
| positive regulation of interleukin-4 production | biological_process | GATA3, CD40LG, HLA-E, LGALS9, IL33, FOXP3, IL20RB |
| positive regulation of interleukin-5 biosynthetic process | biological_process | IL9 |
| positive regulation of interleukin-5 production | biological_process | GATA3, IL33, IL1RL1 |
| positive regulation of interleukin-5 secretion | biological_process | GATA3 |
| positive regulation of interleukin-6 biosynthetic process | biological_process | IFNG, IL1B |
| positive regulation of interleukin-6 production | biological_process | HSPD1, WNT5A, HMGB1, CD36, IL6R, FCER1G, CCR2, TNF, TLR2, TLR4, TLR3, FIGF, IL1B, IL33, IL6, TLR9, NOD2, NOD1, UCN, CRHR2 |
| positive regulation of interleukin-6 secretion | biological_process | F2R, HMGB1, PAEP, LGALS9, IL1B, F2RL1, TWIST1, IL17A, IL17F |
| positive regulation of interleukin-8 biosynthetic process | biological_process | APOA2, TNF, TLR4 |
| positive regulation of interleukin-8 production | biological_process | PTGER4, TNF, TLR2, TLR4, TLR3, SERPINE1, IL1B, PARK7, ADIPOQ, TLR9, NOD2 |
| positive regulation of interleukin-8 secretion | biological_process | F2R, WNT5A, LGALS9, F2RL1 |
| positive regulation of intracellular estrogen receptor signaling pathway | biological_process | PAK1 |
| positive regulation of intracellular protein transport | biological_process | CDC42 |
| positive regulation of intracellular signal transduction | biological_process | SRC, FGF1, TEK |
| positive regulation of intrinsic apoptotic signaling pathway | biological_process | BCL2, CLU, TP53, BCL2L11, BCL2L1, BAX, IL20RA |
| positive regulation of ion transport | biological_process | LEP, TACR2, IL13 |
| positive regulation of IRE1-mediated unfolded protein response | biological_process | BCL2L11, AGR2, BAX |
| positive regulation of isotype switching | biological_process | MSH6 |
| positive regulation of isotype switching to IgA isotypes | biological_process | TGFB1 |
| positive regulation of isotype switching to IgE isotypes | biological_process | STAT6, IL4 |
| positive regulation of isotype switching to IgG isotypes | biological_process | CD40, IFNG, IL4, IL2, TBX21 |
| positive regulation of JAK-STAT cascade | biological_process | AKR1B1, F2R, CCL5, IL10, KIT, LEP, NOTCH1, PRL, IL5, IL6, HES5, IL24, CYP1B1, IL22, ADIPOR1 |
| positive regulation of JNK cascade | biological_process | WNT5A, HMGB1, RASSF2, FLT4, IL1A, TNF, TLR4, CCL21, WNT7A, TLR3, IL1B, CDC42, PLCB1, F2RL1, TLR9, NOD2, CCL19, NOD1, CCR7 |
| positive regulation of JUN kinase activity | biological_process | WNT5A, MAP3K7, TNF, IL1B, EDN1, PAK1, TLR9 |
| positive regulation of keratinocyte apoptotic process | biological_process | SFRP4 |
| positive regulation of keratinocyte differentiation | biological_process | NOTCH1, VDR |
| positive regulation of keratinocyte migration | biological_process | MMP9 |
| positive regulation of keratinocyte proliferation | biological_process | CDH3, TP63 |
| positive regulation of kidney development | biological_process | BMP4, EDNRA |
| positive regulation of killing of cells of other organism | biological_process | NOS2, IFNG, FCER2 |
| positive regulation of L-dopa biosynthetic process | biological_process | PARK7 |
| positive regulation of L-dopa decarboxylase activity | biological_process | PARK7 |
| positive regulation of lamellipodium assembly | biological_process | MTOR, HSP90AA1, WNT1, RAC1 |
| positive regulation of lamellipodium morphogenesis | biological_process | SRC |
| positive regulation of leukocyte adhesion to arterial endothelial cell | biological_process | TNF |
| positive regulation of leukocyte chemotaxis | biological_process | IL6R, CXCL5, CXCL10, IL6, F2RL1, ADAM17, CXCL6 |
| positive regulation of leukocyte mediated cytotoxicity | biological_process | NOS2, CCL2 |
| positive regulation of leukocyte migration | biological_process | VEGFA, ITGA2, KITLG, CCL2, SELP, TACR1 |
| positive regulation of leukotriene production involved in inflammatory response | biological_process | SERPINE1 |
| positive regulation of ligase activity | biological_process | XRCC4 |
| positive regulation of lipase activity | biological_process | RHOC, RHOA |
| positive regulation of lipid biosynthetic process | biological_process | AKT1, MTOR, APOE |
| positive regulation of lipid catabolic process | biological_process | APOA2, IL1B |
| positive regulation of lipid storage | biological_process | NFKB1, C3 |
| positive regulation of lipid transport across blood brain barrier | biological_process | APOE |
| positive regulation of lipopolysaccharide-mediated signaling pathway | biological_process | MIF, BMP6 |
| positive regulation of lipoprotein lipase activity | biological_process | APOA1 |
| positive regulation of lipoprotein metabolic process | biological_process | PEMT |
| positive regulation of long-term neuronal synaptic plasticity | biological_process | KIT |
| positive regulation of long-term synaptic potentiation | biological_process | DRD2 |
| positive regulation of low-density lipoprotein particle receptor catabolic process | biological_process | APOE |
| positive regulation of lung goblet cell differentiation | biological_process | IL13 |
| positive regulation of luteinizing hormone secretion | biological_process | LEP, FOXL2, SMAD4, KISS1 |
| positive regulation of lymphangiogenesis | biological_process | VEGFC |
| positive regulation of lymphocyte apoptotic process | biological_process | FAS |
| positive regulation of lymphocyte proliferation | biological_process | IL12B, TACR1, IL12A, TLR4 |
| positive regulation of macroautophagy | biological_process | KDR, HIF1A, SIRT1, PAFAH1B2, DCN |
| positive regulation of macrophage activation | biological_process | HSPD1, WNT5A, IL13, THBS1, IL33, IL1RL1 |
| positive regulation of macrophage apoptotic process | biological_process | CDKN2A, SIRT1 |
| positive regulation of macrophage chemotaxis | biological_process | CCL5, CSF1, CCL2, THBS1, RARRES2, CX3CL1 |
| positive regulation of macrophage colony-stimulating factor signaling pathway | biological_process | CSF1 |
| positive regulation of macrophage cytokine production | biological_process | WNT5A, CD36, TLR4, CD74 |
| positive regulation of macrophage derived foam cell differentiation | biological_process | CD36, NFKB1, CSF1, AGTR1, PLA2G2A, CSF2 |
| positive regulation of macrophage differentiation | biological_process | CSF1, LIF, RB1, ID2 |
| positive regulation of male gonad development | biological_process | WT1, NR5A1, SEMA3A |
| positive regulation of mammary gland epithelial cell proliferation | biological_process | CCND1 |
| positive regulation of MAP kinase activity | biological_process | FGFR1, SRC, FGF2, VEGFA, KIT, MIF, CD40, FLT1, KITLG, FLT3, EGFR, FGF1, TGFB1, TNF, PDGFA, ERBB2, EGF, KRAS, EDN1, MST1R, EZH2 |
| positive regulation of MAPK cascade | biological_process | FGFR1, F2R, FGFR2, HMGB1, IGFBP3, CD36, KIT, LEP, CTNNB1, KDR, FLT4, TNFRSF1B, IL6R, FLT1, FAS, LIF, TIMP2, IL11, IGFBP4, FLT3, SOX2, INSR, IGF1, ITGB1, PDGFA, TNFRSF11B, IGF2, IL6, PSAP, CDC42, NTRK2, GPER1, KISS1, KSR1, LPAR3 |
| positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway | biological_process | FGFR1 |
| positive regulation of mast cell chemotaxis | biological_process | VEGFA, CCL5, VEGFC, FIGF |
| positive regulation of mast cell cytokine production | biological_process | FCER1G |
| positive regulation of mast cell degranulation | biological_process | FCER1G, IL13, IL4 |
| positive regulation of mast cell proliferation | biological_process | KITLG |
| positive regulation of matrix metallopeptidase secretion | biological_process | PTGER4 |
| positive regulation of megakaryocyte differentiation | biological_process | GATA2 |
| positive regulation of meiotic cell cycle | biological_process | INSR |
| positive regulation of meiotic nuclear division | biological_process | WNT5A, WNT4 |
| positive regulation of melanin biosynthetic process | biological_process | CDH3 |
| positive regulation of melanocyte differentiation | biological_process | BCL2, KITLG |
| positive regulation of melanosome transport | biological_process | CDH3 |
| positive regulation of membrane potential | biological_process | PIAS3 |
| positive regulation of membrane protein ectodomain proteolysis | biological_process | TNFRSF1B, IFNG, APOE, TNF, IL1B, ADAM8 |
| positive regulation of memory T cell differentiation | biological_process | IL12B, IL23A |
| positive regulation of mesenchymal cell proliferation | biological_process | FGFR1, VEGFA, WNT5A, FGFR2, CTNNB1, WNT2, MYC, PDGFA, TP63, IRS2 |
| positive regulation of mesenchymal stem cell proliferation | biological_process | BMP4 |
| positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological_process | LIF, PAX2 |
| positive regulation of metalloendopeptidase activity | biological_process | STAT3 |
| positive regulation of metanephric cap mesenchymal cell proliferation | biological_process | MYC |
| positive regulation of metanephric DCT cell differentiation | biological_process | PAX2 |
| positive regulation of metanephric glomerular visceral epithelial cell development | biological_process | ADIPOQ |
| positive regulation of metanephric glomerulus development | biological_process | AGTR2, PAX2 |
| positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological_process | PDGFA |
| positive regulation of metanephric ureteric bud development | biological_process | WT1 |
| positive regulation of methylation-dependent chromatin silencing | biological_process | DNMT1 |
| positive regulation of MHC class II biosynthetic process | biological_process | IL10, IFNG, TLR4, IL4, SIRT1 |
| positive regulation of microglial cell migration | biological_process | CSF1 |
| positive regulation of microtubule polymerization | biological_process | CDKN1B |
| positive regulation of miRNA metabolic process | biological_process | NFKB1, RELA |
| positive regulation of mismatch repair | biological_process | HMGB1 |
| positive regulation of mitochondrial depolarization | biological_process | KDR, DCN |
| positive regulation of mitochondrial DNA replication | biological_process | STOML2 |
| positive regulation of mitochondrial electron transport, NADH to ubiquinone | biological_process | PARK7 |
| positive regulation of mitochondrial fission | biological_process | KDR, DCN |
| positive regulation of mitochondrial membrane permeability involved in apoptotic process | biological_process | ATF2, BCL2L11, BAX |
| positive regulation of mitochondrial membrane potential | biological_process | GSK3B, STOML2 |
| positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological_process | GSK3B, BAX |
| positive regulation of mitochondrial translation | biological_process | C1QBP |
| positive regulation of mitophagy | biological_process | PARK7, HIF1A |
| positive regulation of mitotic cell cycle | biological_process | CCNB1, BRCA2, BIRC5, EIF4EBP1 |
| positive regulation of mitotic cell cycle phase transition | biological_process | TMOD3 |
| positive regulation of mitotic cell cycle spindle assembly checkpoint | biological_process | XRCC3 |
| positive regulation of mitotic metaphase/anaphase transition | biological_process | RB1 |
| positive regulation of mitotic nuclear division | biological_process | AURKA, INSR, IGF1, IL1A, IL1B, EGF, IGF2, EDN1 |
| positive regulation of monocyte aggregation | biological_process | CD44 |
| positive regulation of monocyte chemotactic protein-1 production | biological_process | LGALS9, IL1B, ADIPOQ, TWIST1 |
| positive regulation of monocyte chemotaxis | biological_process | CCL5, HMGB1, CCR1, CCL2, CCR2, CXCL12, CXCL10, SERPINE1, AIF1 |
| positive regulation of monocyte differentiation | biological_process | CSF1, JUN |
| positive regulation of monocyte extravasation | biological_process | CCR2 |
| positive regulation of mononuclear cell migration | biological_process | LGALS3, TNF, IL4 |
| positive regulation of mononuclear cell proliferation | biological_process | IL12B, CSF1, IL12A |
| positive regulation of monophenol monooxygenase activity | biological_process | CDH3 |
| positive regulation of mRNA 3'-end processing | biological_process | CCNB1 |
| positive regulation of mucus secretion | biological_process | PTGER4 |
| positive regulation of multicellular organism growth | biological_process | BCL2, DRD2, CSF1, GHRH, HSF1, GHRL |
| positive regulation of muscle cell differentiation | biological_process | CTNNB1, CTNNA1, CDC42 |
| positive regulation of muscle hyperplasia | biological_process | AIF1 |
| positive regulation of myelination | biological_process | HGF, NRG1, DICER1 |
| positive regulation of myeloid cell apoptotic process | biological_process | ADIPOQ |
| positive regulation of myeloid cell differentiation | biological_process | HMGB1, LEP, JAG1 |
| positive regulation of myeloid dendritic cell activation | biological_process | KLRK1 |
| positive regulation of myeloid dendritic cell chemotaxis | biological_process | CCL21 |
| positive regulation of myeloid leukocyte cytokine production involved in immune response | biological_process | MIF |
| positive regulation of myeloid leukocyte differentiation | biological_process | KITLG |
| positive regulation of myoblast differentiation | biological_process | IGFBP3, PLCB1 |
| positive regulation of myoblast fusion | biological_process | IL4, GDF15 |
| positive regulation of myoblast proliferation | biological_process | SOX15 |
| positive regulation of myofibroblast contraction | biological_process | PTGER3 |
| positive regulation of myosin light chain kinase activity | biological_process | IL1B |
| positive regulation of myotube differentiation | biological_process | MMP14, MTOR |
| positive regulation of NAD(P)H oxidase activity | biological_process | AGTR1 |
| positive regulation of NAD+ ADP-ribosyltransferase activity | biological_process | TGFB1 |
| positive regulation of natural killer cell activation | biological_process | IL12B, IL12A, IL23A |
| positive regulation of natural killer cell chemotaxis | biological_process | CCL5, CCL3, CXCL14, CCL7 |
| positive regulation of natural killer cell differentiation | biological_process | AXL, IL15, GAS6 |
| positive regulation of natural killer cell mediated cytotoxicity | biological_process | IL12A, CADM1, KLRK1 |
| positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | biological_process | IL12B, IL12A, KLRK1 |
| positive regulation of natural killer cell mediated immunity | biological_process | HLA-E |
| positive regulation of natural killer cell proliferation | biological_process | IL12B, IL15, IL18, IL23A |
| positive regulation of necrotic cell death | biological_process | IL17A |
| positive regulation of nephron tubule epithelial cell differentiation | biological_process | PROM1 |
| positive regulation of neural precursor cell proliferation | biological_process | DLL4 |
| positive regulation of neuroblast proliferation | biological_process | VEGFA, CTNNB1, NOTCH1, DRD2, VEGFC, HIF1A, CX3CL1 |
| positive regulation of neurofibrillary tangle assembly | biological_process | CLU, APOE |
| positive regulation of neurogenesis | biological_process | OPRM1, SERPINF1, WNT2, MTOR, STAR, GPER1 |
| positive regulation of neuron apoptotic process | biological_process | GSK3B, CTNNB1, ATF2, CCL3, CASP3, FASLG, JUN, TP53, MAP2K7, BCL2L11, CDC42, TGFB2, BAX, ATM, AGER |
| positive regulation of neuron death | biological_process | GSK3B, CLU, MTOR, APOE, ATM, AGER |
| positive regulation of neuron differentiation | biological_process | FGFR1, BCL6, BMP4, CCL5, GATA2, TIMP2, BMP6, ZEB1, CCR2, CXCL12, ITGB1, IFNG, IL6, DNMT3B, RHOA |
| positive regulation of neuron maturation | biological_process | BCL2, MTOR |
| positive regulation of neuron migration | biological_process | SEMA3A |
| positive regulation of neuron projection development | biological_process | FGFR1, BMP4, WNT5A, ITGA3, SERPINF1, NME1, LIF, PTN, MTOR, ITGB1, FYN, NTRK2, KAT2B |
| positive regulation of neuron projection regeneration | biological_process | HGF |
| positive regulation of neurotransmitter secretion | biological_process | GPER1 |
| positive regulation of neutrophil apoptotic process | biological_process | ANXA1 |
| positive regulation of neutrophil chemotaxis | biological_process | CXCL8, EDNRA, CXCL1, CXCL2, CCL21, IL1B, CD74, RAC1, C1QBP, CCL19, IL23A, CCR7 |
| positive regulation of neutrophil extravasation | biological_process | PTGER4, PTGER3, ADAM8 |
| positive regulation of neutrophil mediated killing of gram-negative bacterium | biological_process | F2RL1 |
| positive regulation of NF-kappaB import into nucleus | biological_process | IL12B, PTGS2, GREM1, TNF, LGALS9, TLR2, TLR4, TLR3, IL1B, TLR9, IL18, CCL19, IL23A, RHOA |
| positive regulation of NF-kappaB transcription factor activity | biological_process | CD40LG, WNT5A, CLU, NFKB1, AR, CD40, IL6R, GREM1, TGFB1, CLOCK, MAP3K7, PRKCB, LTF, TNF, LGALS9, TLR2, TLR4, TLR3, IL1B, ITGB2, KRAS, ICAM1, AMH, CAT, IL6, RELA, TLR9, NOD2, NFKB2, NOD1, AGER, ADAM8, CRHR2 |
| positive regulation of NFAT protein import into nucleus | biological_process | TNF |
| positive regulation of NIK/NF-kappaB signaling | biological_process | HMGB1, ACTN4, TNF, NOD2, NOD1 |
| positive regulation of nitric oxide biosynthetic process | biological_process | CLU, OPRM1, AKT1, AGTR2, PTX3, MTOR, PTGS2, ESR1, INSR, HSP90AA1, EGFR, IFNG, TNF, TLR4, IL1B, ITGB2, ICAM1, IL6, EDN1, AIF1, KLRK1 |
| positive regulation of nitric-oxide synthase activity | biological_process | AKT1, AGTR2, ESR1, APOE, TERT, KRAS, FCER2, HIF1A, NOD1, SCARB1 |
| positive regulation of nitric-oxide synthase biosynthetic process | biological_process | KDR, CCL2, TLR2, TLR4, FCER2, TLR9, NOD2 |
| positive regulation of NK T cell activation | biological_process | IL12B, IL12A, IL23A |
| positive regulation of NK T cell proliferation | biological_process | IL12B, IL18, IL23A |
| positive regulation of NLRP3 inflammasome complex assembly | biological_process | CD36, TLR4 |
| positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological_process | SMAD2, NODAL |
| positive regulation of non-canonical Wnt signaling pathway | biological_process | WNT5A |
| positive regulation of non-motile cilium assembly | biological_process | Sep-09 |
| positive regulation of norepinephrine secretion | biological_process | OXTR |
| positive regulation of Notch signaling pathway | biological_process | STAT3, KIT, NOTCH1, WNT1, HES5, NOD2, TP63, JAG1, DLL4 |
| positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological_process | TOB1 |
| positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological_process | TOB1 |
| positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway | biological_process | TLR4 |
| positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_process | TLR4 |
| positive regulation of odontogenesis | biological_process | EDNRA, TGFB1, EDN1 |
| positive regulation of odontogenesis of dentin-containing tooth | biological_process | CSF1 |
| positive regulation of oligodendrocyte differentiation | biological_process | PPARG, MTOR, HDAC2, CXCR4 |
| positive regulation of oocyte maturation | biological_process | AURKA |
| positive regulation of optic nerve formation | biological_process | PAX2 |
| positive regulation of organ growth | biological_process | YAP1 |
| positive regulation of ossification | biological_process | BMP4, WNT5A, PTGER4, TACR1, TGFB2 |
| positive regulation of osteoblast differentiation | biological_process | BMP4, GJA1, CTNNB1, PTGER4, IL6R, IL6ST, HGF, BMP6, IGF1, LTF, BMPR1B, CYR61, IL6, TP63, JAG1, DLX5, WNT4 |
| positive regulation of osteoblast proliferation | biological_process | ITGAV, LTF, CYR61, HPSE |
| positive regulation of osteoclast differentiation | biological_process | CCL5, IL12B, CSF1, CCR1, CA2, IFNG, TNF, FOS, CSF1R, KLF10, IL23A, IL17A |
| positive regulation of ovarian follicle development | biological_process | PTGER4 |
| positive regulation of ovulation | biological_process | INHBA, PLAU |
| positive regulation of oxidative phosphorylation uncoupler activity | biological_process | PARK7 |
| positive regulation of oxidative stress-induced cell death | biological_process | MMP3 |
| positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological_process | SOD1, PARK7 |
| positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological_process | MCL1 |
| positive regulation of oxidoreductase activity | biological_process | NOD2, ATP7A |
| positive regulation of p38MAPK cascade | biological_process | XDH, VEGFA, LEP |
| positive regulation of pancreatic stellate cell proliferation | biological_process | IL13 |
| positive regulation of pancreatic trypsinogen secretion | biological_process | MMP13 |
| positive regulation of pathway-restricted SMAD protein phosphorylation | biological_process | INHBA, BMP4, ENG, BMP6, TGFB1, INHA, MSTN, GDF9, TGFB2, SMAD4, NODAL, GDF15 |
| positive regulation of penile erection | biological_process | OXTR |
| positive regulation of peptidase activity | biological_process | FBLN1, MMP14, FN1 |
| positive regulation of peptide hormone secretion | biological_process | FGA |
| positive regulation of peptidyl-cysteine S-nitrosylation | biological_process | ACE |
| positive regulation of peptidyl-serine phosphorylation | biological_process | GSK3B, BCL2, TXN, VEGFA, WNT5A, MIF, AKT1, BRAF, CD44, LIF, IL11, PIK3CA, TGFB1, TNF, LATS1, SPRY2, IL6, CDC42, PARK7, NTRK2, GAS6, PAK1, UCN, ANGPT1 |
| positive regulation of peptidyl-serine phosphorylation of STAT protein | biological_process | LIF, IFNG |
| positive regulation of peptidyl-threonine phosphorylation | biological_process | GSK3B, WNT5A, MAPK1, CHI3L1, TGFB1, EGF, PLK1 |
| positive regulation of peptidyl-tyrosine autophosphorylation | biological_process | VEGFA, ACE, GREM1 |
| positive regulation of peptidyl-tyrosine phosphorylation | biological_process | SRC, VEGFA, CD36, MIF, IL6R, HGF, CD44, KITLG, TDGF1, LIF, IL11, EFNA1, MTOR, VEGFC, IGF1, ITGB3, ITGB1, TGFB1, TP53, CD4, NRP1, EGF, IGF2, ICAM1, CD74, IL4, IL5, IL6, NRG1, ADIPOQ, ANGPT1 |
| positive regulation of peripheral T cell tolerance induction | biological_process | FOXP3 |
| positive regulation of PERK-mediated unfolded protein response | biological_process | AGR2 |
| positive regulation of peroxisome proliferator activated receptor signaling pathway | biological_process | LEP |
| positive regulation of phagocytosis | biological_process | MBL2, GATA2, PTX3, FCER1G, AHSG, TNF, C3, IL1B, GAS6 |
| positive regulation of phagocytosis, engulfment | biological_process | PPARG, CD36, ITGA2, GATA2, F2RL1, AGER |
| positive regulation of phosphatidylinositol 3-kinase activity | biological_process | SRC, FGF2, KIT, PDGFRA, FLT1, FLT3, TGFB1, CCL21, CDC42, RAC1, PTK2, TEK, NOD2, CCL19, CCR7 |
| positive regulation of phosphatidylinositol 3-kinase signaling | biological_process | FGFR1, FSHR, F2R, CCL5, KIT, LEP, ERBB3, KDR, PDGFRA, HGF, FLT1, SELP, FLT3, IGF1, PDGFA, FYN, CAT, TGFB2, PTK2, NRG1, NTRK2, TEK, F2RL1, SIRT1, GPER1, ANGPT1, DCN |
| positive regulation of phospholipase A2 activity | biological_process | AGTR1 |
| positive regulation of phospholipase activity | biological_process | FGFR1, FGFR2, CYR61 |
| positive regulation of phospholipase C activity | biological_process | FGFR1, FGF2, KIT, PDGFRA, FLT1, ESR1 |
| positive regulation of phospholipid efflux | biological_process | APOE |
| positive regulation of phosphoprotein phosphatase activity | biological_process | AGTR2 |
| positive regulation of phosphorylation | biological_process | ITGA6, CCL5, MIF, AR, EGFR, ANG, THBS1, EGF |
| positive regulation of pinocytosis | biological_process | AXL, ACTN4 |
| positive regulation of platelet activation | biological_process | SELP, TLR4 |
| positive regulation of platelet-derived growth factor production | biological_process | PTGS2 |
| positive regulation of platelet-derived growth factor receptor signaling pathway | biological_process | SRC, F3 |
| positive regulation of podosome assembly | biological_process | SRC, TNF, CSF2, IL5 |
| positive regulation of positive chemotaxis | biological_process | VEGFA, F3, KDR, ITGA2, SMAD3, F2RL1 |
| positive regulation of postsynaptic membrane organization | biological_process | APOE |
| positive regulation of potassium ion transmembrane transporter activity | biological_process | AGER |
| positive regulation of potassium ion transport | biological_process | DPP6 |
| positive regulation of presynaptic membrane organization | biological_process | APOE |
| positive regulation of pri-miRNA transcription from RNA polymerase II promoter | biological_process | STAT3, JUN, TERT, FOS, HIF1A |
| positive regulation of production of miRNAs involved in gene silencing by miRNA | biological_process | EGFR |
| positive regulation of progesterone secretion | biological_process | RETN |
| positive regulation of programmed cell death | biological_process | CDKN1A, TNF |
| positive regulation of prostaglandin biosynthetic process | biological_process | PLA2G4A, PTGS2, ANXA1 |
| positive regulation of prostaglandin secretion | biological_process | IL1B, EDN1 |
| positive regulation of prostaglandin secretion involved in immune response | biological_process | MIF |
| positive regulation of prostaglandin-E synthase activity | biological_process | NOD2 |
| positive regulation of prostaglandin-endoperoxide synthase activity | biological_process | EDN1, NOD2 |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological_process | GCLC, GSK3B, CLU, AKT1, AURKA, SMAD7, PSMD10, IL33, PLK1 |
| positive regulation of protein autophosphorylation | biological_process | SRC, VEGFA, RASSF2, VEGFC, PDGFA |
| positive regulation of protein binding | biological_process | GSK3B, BMP4, WNT5A, TERT |
| positive regulation of protein catabolic process | biological_process | GSK3B, WNT5A, GJA1, CDKN1B, C4BPA, FOXO1, STX5 |
| positive regulation of protein complex assembly | biological_process | GSK3B, VEGFA, TGFB1, TNF |
| positive regulation of protein complex disassembly | biological_process | TNF |
| positive regulation of protein dephosphorylation | biological_process | TGFB1 |
| positive regulation of protein export from nucleus | biological_process | GSK3B, TP53, IL1B, GAS6 |
| positive regulation of protein homodimerization activity | biological_process | PARK7 |
| positive regulation of protein homooligomerization | biological_process | FAS, BCL2L11 |
| positive regulation of protein import into nucleus | biological_process | LEP, TGFB1 |
| positive regulation of protein import into nucleus, translocation | biological_process | BRCA1, IGF1, HSP90AA1, IL6 |
| positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological_process | BCL2, TP53, BCL2L11, YWHAH, TP63 |
| positive regulation of protein K63-linked ubiquitination | biological_process | PTPN22 |
| positive regulation of protein kinase A signaling | biological_process | MIF, ADIPOQ |
| positive regulation of protein kinase activity | biological_process | WNT5A, RASSF2, CSF1, SDC4, TNF, CD4, CCL21, CYR61, PTK2, NRG1, GAS6, ADIPOQ, CCL19, CCR7 |
| positive regulation of protein kinase B signaling | biological_process | SRC, TXN, GATA3, CHI3L1, F3, LEP, CCL3, AXL, IGFBP5, MTOR, AKR1C3, AKR1C2, INSR, EGFR, TGFB1, TNF, PDGFA, CCL21, SPRY2, THBS1, GPX1, IGF2, IL6, C1QBP, PTK2, NRG1, PARK7, HPSE, GAS6, TEK, CCL19, MST1R, ADAM8, ANGPT1, CCR7 |
| positive regulation of protein kinase C activity | biological_process | WNT5A |
| positive regulation of protein kinase C signaling | biological_process | VEGFA, WNT5A, FLT4, CD40 |
| positive regulation of protein kinase D signaling | biological_process | VEGFA |
| positive regulation of protein localization to cell surface | biological_process | TNF, NRG1 |
| positive regulation of protein localization to early endosome | biological_process | VEGFA |
| positive regulation of protein localization to nucleolus | biological_process | TERT |
| positive regulation of protein localization to nucleus | biological_process | AKT1, LIF, TGFB1, FYN, PLK1, TGFB2, PARK7, CDKN2A |
| positive regulation of protein localization to synapse | biological_process | WNT5A, WNT7A |
| positive regulation of protein O-linked glycosylation | biological_process | IL15 |
| positive regulation of protein oligomerization | biological_process | TP53, MMP1, MMP3, BAX |
| positive regulation of protein phosphorylation | biological_process | CCND1, VEGFA, BMP4, WNT5A, HMGB1, MMP9, MIF, AKT1, PTGER4, KDR, FLT4, CD40, ENG, EDNRA, MTOR, PTGER3, CHEK2, INSR, ITGB3, EGFR, FGF1, TGFB1, TNF, C3, ERBB2, CYR61, MAP2K7, TLR3, ANXA2, IL1B, KRAS, IGF2, WNT1, IL4, CRH, CSF1R, CDC42, RAC1, PTK2, NTRK2, GAS6, PLAUR, TEK, PAK1, ADIPOQ, AIF1, RARRES2, SIRT1, ADAM17, AGER, GPER1, UCN, IL2 |
| positive regulation of protein polyubiquitination | biological_process | HAMP |
| positive regulation of protein processing | biological_process | ADAM8 |
| positive regulation of protein secretion | biological_process | PTGER4, BMP6, IL13, VEGFC, IGF1, ANG, TGFB1, FGA, IL1A, TGFB2, ADAM8 |
| positive regulation of protein serine/threonine kinase activity | biological_process | SRC, LTF, SPRY2, IGF2, CSF1R, EZH2, RHOA |
| positive regulation of protein sumoylation | biological_process | ARNT, CDKN2A, PIAS3 |
| positive regulation of protein targeting to membrane | biological_process | CCL2, ERBB2 |
| positive regulation of protein targeting to mitochondrion | biological_process | NRG1, PEMT |
| positive regulation of protein transport | biological_process | SRC, TNF |
| positive regulation of protein tyrosine kinase activity | biological_process | CCL5, ERBB3, ACE, GREM1, CSF1R, NRG1, GAS6, GHRL |
| positive regulation of protein ubiquitination | biological_process | BRCA1, SMAD7, PSMD10, ANGPT1 |
| positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological_process | CLU, CCDC22, EGF, PTEN, PTK2 |
| positive regulation of proteolysis | biological_process | PLK1, HDAC2 |
| positive regulation of pseudopodium assembly | biological_process | KIT, CCL21, CDC42, F2RL1, CCR7 |
| positive regulation of pyrroline-5-carboxylate reductase activity | biological_process | PARK7 |
| positive regulation of Rac protein signal transduction | biological_process | KRAS |
| positive regulation of Ras protein signal transduction | biological_process | CSF1, KITLG, IGF1, NRG1 |
| positive regulation of reactive oxygen species biosynthetic process | biological_process | PARK7 |
| positive regulation of reactive oxygen species metabolic process | biological_process | XDH, CD36, LEP, CDKN1A, AGTR1, AKR1C3, TP53, THBS1, PLAU, NFE2L2, AGER |
| positive regulation of receptor activity | biological_process | GREM1, ANXA2, IGF2, SRA1 |
| positive regulation of receptor binding | biological_process | MMP9 |
| positive regulation of receptor biosynthetic process | biological_process | EDN1, HDAC2, HIF1A, HDAC1 |
| positive regulation of receptor catabolic process | biological_process | HAMP |
| positive regulation of receptor clustering | biological_process | TGFB1 |
| positive regulation of receptor internalization | biological_process | VEGFA, DRD2, SELE, GREM1, HAMP, ANGPT1, SFRP4 |
| positive regulation of receptor-mediated endocytosis | biological_process | CCL21, SERPINE1, TF, CCL19 |
| positive regulation of regulatory T cell differentiation | biological_process | HLA-G, TGFB1, FOXP3, IL2 |
| positive regulation of release of cytochrome c from mitochondria | biological_process | MMP9, TNFSF10, TP53, BCL2L11, BAX, PLAUR, GPER1 |
| positive regulation of release of sequestered calcium ion into cytosol | biological_process | F2R, CXCR3, EDNRA, IL13, CXCL10, BAX, GPER1 |
| positive regulation of renal albumin absorption | biological_process | ADIPOQ |
| positive regulation of renal sodium excretion | biological_process | PTGER4, DRD2, AGTR2, TACR1, EDN1 |
| positive regulation of renin secretion into blood stream | biological_process | F2RL1 |
| positive regulation of respiratory burst | biological_process | INSR |
| positive regulation of response to cytokine stimulus | biological_process | WNT5A |
| positive regulation of response to DNA damage stimulus | biological_process | HMGA2, MYC |
| positive regulation of response to food | biological_process | GHRL |
| positive regulation of response to interferon-gamma | biological_process | HPX |
| positive regulation of retinal ganglion cell axon guidance | biological_process | VEGFA, NRP1 |
| positive regulation of Rho protein signal transduction | biological_process | F2R, APOA1, RAC1, F2RL1 |
| positive regulation of RNA splicing | biological_process | PIK3R1 |
| positive regulation of saliva secretion | biological_process | TACR1 |
| positive regulation of sarcomere organization | biological_process | EDN1 |
| positive regulation of satellite cell activation involved in skeletal muscle regeneration | biological_process | SOX15 |
| positive regulation of Schwann cell differentiation | biological_process | RELA, DICER1 |
| positive regulation of sensory perception of pain | biological_process | MTOR, P2RX3 |
| positive regulation of sequence-specific DNA binding transcription factor activity | biological_process | PPARG, IL10, KIT, AKT1, CTNNB1, ATF2, WNT2, ESR1, TNF, IL1B, WNT1, IL4, IL5, IL6, PTEN, PARK7, ESR2, PPRC1, NODAL |
| positive regulation of serotonin secretion | biological_process | CRHR2 |
| positive regulation of signal transduction | biological_process | CRK, GATA3, TOB1, ADIPOQ, GRB14 |
| positive regulation of signal transduction by p53 class mediator | biological_process | CDKN2A, CHD5 |
| positive regulation of skeletal muscle acetylcholine-gated channel clustering | biological_process | PTN |
| positive regulation of skeletal muscle fiber development | biological_process | BCL2 |
| positive regulation of skeletal muscle hypertrophy | biological_process | MTOR |
| positive regulation of skeletal muscle tissue development | biological_process | CTNNB1 |
| positive regulation of SMAD protein import into nucleus | biological_process | BMP4, BMP6, TGFB1, POU5F1, SMAD4, NODAL |
| positive regulation of smooth muscle cell apoptotic process | biological_process | IL12B, CDKN2A, IL12A, IFNG |
| positive regulation of smooth muscle cell chemotaxis | biological_process | AIF1 |
| positive regulation of smooth muscle cell differentiation | biological_process | TGFB1 |
| positive regulation of smooth muscle cell migration | biological_process | BCL2, SRC, CCL5, F3, PTGER4, ITGA2, IGF1, NRP1, PLAU, AGER, POSTN, RETN |
| positive regulation of smooth muscle cell proliferation | biological_process | GSK3B, AKR1B1, BMP4, CCL5, FGFR2, SHC1, IL6R, ITGA2, FLT1, HMOX1, MTOR, IL13, PTGS2, IGF1, JUN, TNF, IL6, EDN1, HIF1A, FOXP1, HES5, AIF1, ID2, AGER, CX3CL1, RETN |
| positive regulation of smooth muscle contraction | biological_process | F2R, ITGA2, TACR2, TACR1, PTGS1, PTGS2, ADA, EDN1 |
| positive regulation of smooth muscle contraction involved in micturition | biological_process | PTGER3 |
| positive regulation of smoothened signaling pathway | biological_process | CTNNA1, IHH |
| positive regulation of sodium ion transport | biological_process | AKT1, SGK1 |
| positive regulation of sodium:proton antiporter activity | biological_process | ACTN4 |
| positive regulation of sprouting angiogenesis | biological_process | FGF2, HMGB1, JAK1, FGF1 |
| positive regulation of STAT protein import into nucleus | biological_process | LEP, IL6 |
| positive regulation of stem cell differentiation | biological_process | GSK3B |
| positive regulation of stem cell population maintenance | biological_process | YAP1 |
| positive regulation of stem cell proliferation | biological_process | HMGA2, EPCAM, TERT |
| positive regulation of steroid hormone biosynthetic process | biological_process | CYP17A1 |
| positive regulation of store-operated calcium channel activity | biological_process | BMP4 |
| positive regulation of stress fiber assembly | biological_process | SDC4, BRAF, TACR1, MTOR, APOA1, RAC1, SMAD3, PAK1, LIMK1, WNT4, KISS1R, RHOA |
| positive regulation of stress-activated MAPK cascade | biological_process | TLR4, IL1B, TGFB2, NOD2, NOD1, CRHR2 |
| positive regulation of striated muscle cell differentiation | biological_process | NRG1 |
| positive regulation of striated muscle tissue development | biological_process | GJA1 |
| positive regulation of substance P secretion | biological_process | PTGER4 |
| positive regulation of substance P secretion, neurotransmission | biological_process | PTGER4 |
| positive regulation of substrate adhesion-dependent cell spreading | biological_process | BRAF, FGA, APOA1, CDC42, RAC1, C1QBP, OLFM4 |
| positive regulation of substrate-dependent cell migration, cell attachment to substrate | biological_process | FBLN1, FN1 |
| positive regulation of superoxide anion generation | biological_process | GSTP1, TGFB1, SOD1, CRP, F2RL1 |
| positive regulation of superoxide dismutase activity | biological_process | TNF, PARK7 |
| positive regulation of supramolecular fiber organization | biological_process | GPX1 |
| positive regulation of synapse assembly | biological_process | BDNF, OXTR, WNT7A, NTRK2, GHRL |
| positive regulation of synapse structural plasticity | biological_process | CDC42 |
| positive regulation of synaptic plasticity | biological_process | PTGS2 |
| positive regulation of synaptic transmission | biological_process | CCL2, KISS1R, KISS1, RETN |
| positive regulation of synaptic transmission, cholinergic | biological_process | TACR1, IFNG |
| positive regulation of synaptic transmission, GABAergic | biological_process | TACR1, OXTR, CA2 |
| positive regulation of synaptic transmission, glutamatergic | biological_process | OXTR, PTGS2, NTRK2 |
| positive regulation of systemic arterial blood pressure | biological_process | ENG |
| positive regulation of T cell activation | biological_process | HSPD1, CCL2, CCR2, MAP3K7, CD4, ADA, HLA-DPB1 |
| positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological_process | LGALS9 |
| positive regulation of T cell anergy | biological_process | FOXP3 |
| positive regulation of T cell apoptotic process | biological_process | CCL5, IDO1 |
| positive regulation of T cell chemotaxis | biological_process | WNT5A, CCL5, CCR2, CXCL13, ADAM17 |
| positive regulation of T cell costimulation | biological_process | CCR7 |
| positive regulation of T cell cytokine production | biological_process | MAP3K7 |
| positive regulation of T cell differentiation | biological_process | GATA3, IL12A, ADA, IL2RA, CD74, IL4, IL2 |
| positive regulation of T cell differentiation in thymus | biological_process | ADA, ADAM8, IHH |
| positive regulation of T cell mediated cytotoxicity | biological_process | IL12B, HLA-E, IL12A, HLA-A, IL23A |
| positive regulation of T cell mediated immune response to tumor cell | biological_process | HSPD1 |
| positive regulation of T cell mediated immunity | biological_process | IL1B |
| positive regulation of T cell migration | biological_process | CCL5, CXCL12, CXCL10, CCL21, AIF1, ADAM8 |
| positive regulation of T cell proliferation | biological_process | CD40LG, CCL5, IL12B, LEP, IL6ST, IL15, VCAM1, IL12A, IFNG, ANXA1, CD4, IL1B, PNP, IL2RA, HLA-DPB1, IL4, IL6, AIF1, CCL19, IL23A, IL2 |
| positive regulation of T cell receptor signaling pathway | biological_process | ADA, CCR7 |
| positive regulation of T cell tolerance induction | biological_process | IDO1, HLA-G, FOXP3 |
| positive regulation of T-helper 1 cell differentiation | biological_process | ANXA1, CCL19 |
| positive regulation of T-helper 1 type immune response | biological_process | IL12B, CCR2, IL23A |
| positive regulation of T-helper 17 cell lineage commitment | biological_process | IL12B, IL23A |
| positive regulation of T-helper 17 type immune response | biological_process | IL12B, IL23A |
| positive regulation of T-helper 2 cell cytokine production | biological_process | GATA3 |
| positive regulation of T-helper 2 cell differentiation | biological_process | IL6 |
| positive regulation of tau-protein kinase activity | biological_process | CLU |
| positive regulation of telomerase activity | biological_process | MAPK1, CTNNB1, GREM1, MAP2K7 |
| positive regulation of telomerase catalytic core complex assembly | biological_process | ATM |
| positive regulation of telomere capping | biological_process | MAPK1, MAP2K7 |
| positive regulation of telomere maintenance via telomerase | biological_process | MAPK1, CTNNB1, MAP2K7, ATM |
| positive regulation of telomere maintenance via telomere lengthening | biological_process | ATM |
| positive regulation of thymocyte apoptotic process | biological_process | WNT5A, TP53, ADAM8 |
| positive regulation of thyroid hormone generation | biological_process | GATA3 |
| positive regulation of tissue remodeling | biological_process | IL12B, IL15, IL18, IL23A, IL2 |
| positive regulation of tolerance induction | biological_process | HLA-G |
| positive regulation of toll-like receptor 2 signaling pathway | biological_process | HMGB1, F2RL1 |
| positive regulation of toll-like receptor 3 signaling pathway | biological_process | F2RL1, PTPN22 |
| positive regulation of toll-like receptor 4 signaling pathway | biological_process | HMGB1, LTF, F2RL1, PTPN22 |
| positive regulation of toll-like receptor 9 signaling pathway | biological_process | HMGB1 |
| positive regulation of toll-like receptor signaling pathway | biological_process | TLR2, TLR3, TLR9 |
| positive regulation of TOR signaling | biological_process | LEP, GAS6 |
| positive regulation of TRAIL production | biological_process | HLA-E |
| positive regulation of TRAIL-activated apoptotic signaling pathway | biological_process | TIMP3, PTEN |
| positive regulation of transcription factor import into nucleus | biological_process | CDH1, PIK3R1, SMAD3 |
| positive regulation of transcription from RNA polymerase I promoter | biological_process | ERBB2 |
| positive regulation of transcription from RNA polymerase II promoter | biological_process | GSK3B, EGR1, GATA3, ITGA6, INHBA, YAP1, FGF2, VEGFA, MET, STAT3, BMP4, CDX1, WNT5A, HMGA2, PPARG, TNFRSF1A, FGFR2, HMGB1, PIK3R1, IL10, AKT1, CTNNB1, ATF2, EPCAM, BRCA1, NFKB1, HMGA1, AR, WNT2, AHR, NOTCH1, DRD2, CXCR3, VDR, CD40, ENG, GATA2, HGF, USF1, LIF, STAT6, HOXA10, WT1, IL11, HNF1B, BMP6, ARNT, SOX2, ZEB1, ESR1, IGF1, GREM1, EGFR, JUN, FGF1, IFNG, TGFB1, CLOCK, FSTL3, IL1A, TP53, TNF, MYC, CXCL10, TLR2, TLR4, BMPR1B, SMAD7, MEIS1, NR5A2, CYR61, RB1, WNT7A, SOX15, FOS, TLR3, NR3C1, SERPINE1, PGR, IL1B, IL33, CGA, FSHB, WNT1, IL4, IL6, EDN1, COPS5, YBX1, HDAC2, SMAD3, RELA, NRG1, FOXL2, PARK7, HIF1A, HES5, ATP1B4, FOXO1, NR5A1, HSF1, SMAD2, F2RL1, HEY1, TLR9, NFE2L2, NOD2, ESR2, PPARA, NFKB2, POU5F1, KAT2B, HDAC1, FOXP3, SIRT1, SMAD4, TWIST1, GPER1, CDKN2A, TP63, GATA6, JAG1, PAX2, USF2, UCN, IL23A, DLX5, IL2, IHH, IL17A, PPRC1, IL17F, NODAL, NANOG, GATA5, AHRR, TET3, MAF, DCN, TET2, TET1, LILRB1, CREB3L1 |
| positive regulation of transcription from RNA polymerase II promoter by glucose | biological_process | USF1, USF2 |
| positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological_process | TP53, CREB3L1 |
| positive regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological_process | VEGFA, NOTCH1, HIF1A |
| positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress | biological_process | NFE2L2 |
| positive regulation of transcription from RNA polymerase II promoter in response to stress | biological_process | MUC1, NFE2L2 |
| positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | biological_process | SMAD4, DLX5 |
| positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | biological_process | GREM1 |
| positive regulation of transcription from RNA polymerase III promoter | biological_process | AR, MTOR, ERBB2 |
| positive regulation of transcription initiation from RNA polymerase II promoter | biological_process | HNF1B |
| positive regulation of transcription involved in G1/S transition of mitotic cell cycle | biological_process | ID2 |
| positive regulation of transcription of Notch receptor target | biological_process | NOTCH1, NOTCH4 |
| positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter | biological_process | MTOR |
| positive regulation of transcription regulatory region DNA binding | biological_process | GATA3, HMGA2, IGF1, TGFB1, RB1, PARK7, TWIST1 |
| positive regulation of transcription, DNA-templated | biological_process | EGR1, SRC, CDH1, GATA3, INHBA, FGF2, STAT3, NR2F2, BMP4, F2R, WNT5A, HMGA2, PPARG, MAPK1, IL10, CTNNB1, BRCA1, NFKB1, HMGA1, AR, AHR, NOTCH1, AGTR2, BRCA2, USF1, WT1, HNF1B, MDK, ARNT, HOXA11, SOX2, CHEK2, PSMD9, ESR1, INSR, IGF1, GREM1, JUN, IFNG, TGFB1, CLOCK, TP53, TNF, MYC, NR5A2, RB1, WNT7A, ARID1A, SNAI1, MSTN, FOS, TGFB1I1, IL1B, EGF, WNT1, IL4, IL5, IL6, RUNX3, HDAC2, SMAD3, RELA, FOXL2, HIF1A, HES5, FOXO1, PLCB1, NR5A1, SMAD2, NFE2L2, ESR2, PPARA, KAT2B, HDAC1, FOXP3, ID2, SMAD4, YWHAH, PIM2, CDKN2A, TP63, GATA6, NAA15, PAX2, USF2, DLX5, WNT4, PTGES2, NOTCH4, GATA5, TBX21 |
| positive regulation of transforming growth factor beta production | biological_process | PTGS2, LGALS9 |
| positive regulation of transforming growth factor beta receptor signaling pathway | biological_process | TGFB1I1, THBS1, SMAD4, ADAM17 |
| positive regulation of transforming growth factor beta1 production | biological_process | THBS1, FOXP3, CX3CL1 |
| positive regulation of transforming growth factor beta2 production | biological_process | ATF2 |
| positive regulation of transforming growth factor beta3 production | biological_process | SMAD3 |
| positive regulation of translation | biological_process | MAPK1, ITGA2, MTOR, ERBB2, THBS1, IL6, ELAVL1, UCN |
| positive regulation of translational initiation | biological_process | CCL5 |
| positive regulation of translational initiation by iron | biological_process | TNF |
| positive regulation of transmission of nerve impulse | biological_process | ITGA2, IL6 |
| positive regulation of transporter activity | biological_process | PON1, SGK1 |
| positive regulation of triglyceride biosynthetic process | biological_process | SCARB1 |
| positive regulation of triglyceride catabolic process | biological_process | APOA1 |
| positive regulation of trophectodermal cell proliferation | biological_process | IGF1 |
| positive regulation of trophoblast cell migration | biological_process | C1QBP |
| positive regulation of tumor necrosis factor (ligand) superfamily member 11 production | biological_process | IFNG, ADAM8 |
| positive regulation of tumor necrosis factor biosynthetic process | biological_process | CCR2, HSPB1, TLR4, THBS1 |
| positive regulation of tumor necrosis factor production | biological_process | HMGB1, CLU, PIK3R1, CD36, IL12B, CCL3, CCL2, HLA-E, FCER1G, CCR2, IFNG, TLR2, TLR4, TLR3, HDAC2, TLR9, NOD2, CCL19, NOD1, TWIST1, IL23A |
| positive regulation of tumor necrosis factor secretion | biological_process | LGALS9 |
| positive regulation of type 2 immune response | biological_process | IDO1, IL33, CD74, NOD2 |
| positive regulation of type B pancreatic cell apoptotic process | biological_process | IL6, AGER |
| positive regulation of type I hypersensitivity | biological_process | FCER1G |
| positive regulation of type I interferon production | biological_process | CTNNB1, NFKB1, STAT6, TLR3, RELA, NFKB2, PTPN22 |
| positive regulation of type I interferon-mediated signaling pathway | biological_process | WNT5A |
| positive regulation of type IIa hypersensitivity | biological_process | FCER1G, C3 |
| positive regulation of type III hypersensitivity | biological_process | FCER1G |
| positive regulation of type III interferon production | biological_process | TLR3 |
| positive regulation of tyrosine 3-monooxygenase activity | biological_process | PARK7 |
| positive regulation of tyrosine phosphorylation of STAT protein | biological_process | CCL5, FLT3 |
| positive regulation of tyrosine phosphorylation of Stat1 protein | biological_process | TNFRSF1A, KIT, CD40, IL6ST, LIF, IFNG, HPX |
| positive regulation of tyrosine phosphorylation of Stat3 protein | biological_process | VEGFA, STAT3, KIT, IL12B, LEP, PTGER4, IL6R, IL6ST, CNTF, IL15, LIF, SOCS3, IL6, CSF1R, HDAC2, HES5, IL18, IL24, IL23A |
| positive regulation of tyrosine phosphorylation of Stat4 protein | biological_process | IL12B, IL12A, IL23A |
| positive regulation of tyrosine phosphorylation of Stat5 protein | biological_process | KIT, IL12B, IGF1, FYN, CSF2, IL4, IL23A, IL2 |
| positive regulation of tyrosine phosphorylation of Stat6 protein | biological_process | IL13 |
| positive regulation of ubiquitin protein ligase activity | biological_process | PTEN, PLK1 |
| positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | biological_process | CCNB1, PSMD9, PSMD10, PLK1 |
| positive regulation of ubiquitin-protein transferase activity | biological_process | PLK1 |
| positive regulation of ureteric bud formation | biological_process | GATA3 |
| positive regulation of urine volume | biological_process | PTGER4, DRD2, EDN1 |
| positive regulation of uterine smooth muscle contraction | biological_process | TACR2, TACR1, OXTR, GPER1 |
| positive regulation of vascular endothelial growth factor production | biological_process | BRCA1, FLT4, IL6ST, ARNT, PTGS2, TGFB1, IL1A, C3, IL1B, C5, HPSE, HIF1A, CYP1B1, NODAL |
| positive regulation of vascular endothelial growth factor receptor signaling pathway | biological_process | VEGFA, FLT1, ARNT, ITGB3, PRKCB, IL1B, HIF1A |
| positive regulation of vascular permeability | biological_process | VEGFA, TACR2, TACR1, TGFB1, PTP4A3, UCN |
| positive regulation of vascular smooth muscle cell differentiation | biological_process | KIT |
| positive regulation of vasculogenesis | biological_process | KDR, ADM |
| positive regulation of vasoconstriction | biological_process | F2R, GJA1, AKT1, SHC1, TACR1, PTGS1, OXTR, PTGS2, PTGER3, FGA, ICAM1 |
| positive regulation of vasodilation | biological_process | NOS2, GJA1, AGTR2, HMOX1, NOS3, ADM, F2RL1, ESR2, KAT2B, GPER1, UCN |
| positive regulation of vesicle fusion | biological_process | PLA2G4A, ANXA1, ANXA2 |
| positive regulation of viral entry into host cell | biological_process | LGALS1, LGALS9 |
| positive regulation of viral genome replication | biological_process | CCL5, NOTCH1, NR5A2 |
| positive regulation of viral transcription | biological_process | NOTCH1 |
| positive regulation of vitamin D 24-hydroxylase activity | biological_process | VDR |
| positive regulation of vitamin D biosynthetic process | biological_process | IFNG, TNF |
| positive regulation of voltage-gated chloride channel activity | biological_process | CFTR |
| positive regulation of Wnt signaling pathway | biological_process | FGFR2, TERT, TLR2, MBD2 |
| positive regulation of wound healing | biological_process | HMGB1, PTGER4, ANXA1 |
| positive regulation of xenophagy | biological_process | NOD1 |
| positive T cell selection | biological_process | BRAF |
| positive thymic T cell selection | biological_process | CD74 |
| post-anal tail morphogenesis | biological_process | WNT5A, TP63 |
| post-embryonic animal organ morphogenesis | biological_process | BCL2L11 |
| post-embryonic camera-type eye development | biological_process | VEGFA |
| post-embryonic camera-type eye morphogenesis | biological_process | BAX |
| post-embryonic development | biological_process | BCL2, GATA3, BMP4, FGFR2, IGF2R, MTOR, CYP1A2, BCL2L11, PRDM1, BAX, SMAD2, SEMA3C, TET2 |
| post-Golgi vesicle-mediated transport | biological_process | PLCB3 |
| post-translational protein modification | biological_process | STS, ARSH |
| posterior mesonephric tubule development | biological_process | WT1 |
| postreplication repair | biological_process | MSH2, BRCA1 |
| postsynaptic density assembly | biological_process | PTEN |
| potassium ion transport | biological_process | CDKN1B |
| pre-B cell allelic exclusion | biological_process | ATM |
| pre-miRNA processing | biological_process | DICER1 |
| preantral ovarian follicle growth | biological_process | AMH |
| prepulse inhibition | biological_process | DRD2, PTEN |
| presynaptic active zone assembly | biological_process | PCDH17 |
| presynaptic membrane assembly | biological_process | PTEN |
| primary miRNA processing | biological_process | SMAD3, SMAD2 |
| primary ovarian follicle growth | biological_process | FSHR |
| primary sex determination | biological_process | NR5A1 |
| primitive erythrocyte differentiation | biological_process | VEGFA |
| primitive streak formation | biological_process | WNT5A, NODAL |
| pro-B cell differentiation | biological_process | FLT3 |
| pro-T cell differentiation | biological_process | GATA3 |
| production of miRNAs involved in gene silencing by miRNA | biological_process | DICER1 |
| production of siRNA involved in RNA interference | biological_process | TERT, DICER1 |
| progesterone biosynthetic process | biological_process | ADM, STAR, FSHB, LHB |
| progesterone metabolic process | biological_process | AKR1C3, AKR1C2, CYP17A1, AKR1C1, SRD5A1 |
| progesterone receptor signaling pathway | biological_process | SRC |
| progesterone secretion | biological_process | INHBA |
| programmed cell death | biological_process | TP53 |
| programmed necrotic cell death | biological_process | CASP1 |
| prolactin secretion | biological_process | TACR2, ANXA1 |
| prolactin signaling pathway | biological_process | PRLR |
| pronephric field specification | biological_process | PAX2 |
| pronephric nephron tubule development | biological_process | HNF1B |
| pronephros development | biological_process | HNF1B, PAX2 |
| prostaglandin biosynthetic process | biological_process | PTGDS, MIF, PTGS1, PTGS2, PTGES, CD74, EDN1, PTGES2 |
| prostaglandin metabolic process | biological_process | PTGDS, TNFRSF1A, HPGD, PTGS1, PTGS2, AKR1C3, AKR1C2, PTGES, PTGES2 |
| prostaglandin receptor internalization | biological_process | PTGER3 |
| prostaglandin secretion | biological_process | NOS2, LEP, ABCC4 |
| prostaglandin transport | biological_process | SLCO2A1 |
| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | biological_process | FGFR2, ESR1 |
| prostate epithelial cord elongation | biological_process | FGFR2, ESR1 |
| prostate gland development | biological_process | WNT5A, AR, ANXA1, FKBP4, ESR2, TP63 |
| prostate gland epithelium morphogenesis | biological_process | NOTCH1, TNC |
| prostate gland growth | biological_process | CYP19A1, PRLR, PSAP, PTEN |
| prostate gland morphogenesis | biological_process | BMP4, FGFR2 |
| prostatic bud formation | biological_process | TP63 |
| proteasomal ubiquitin-independent protein catabolic process | biological_process | NFE2L2 |
| proteasome regulatory particle assembly | biological_process | PSMD9, PSMD10 |
| proteasome-mediated ubiquitin-dependent protein catabolic process | biological_process | GSK3B, CTNNB1, UCHL1, PSMD9, CLOCK, TP53, PSMD10, NFE2L2, SIRT1 |
| protection from natural killer cell mediated cytotoxicity | biological_process | HLA-E, HLA-B |
| protein acetylation | biological_process | FOXO1, KAT2B |
| protein ADP-ribosylation | biological_process | SIRT1 |
| protein autophosphorylation | biological_process | GSK3B, FGFR1, SRC, FGFR2, KIT, AKT1, KDR, FLT4, PDGFRA, JAK1, FLT1, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, IGF1R, ERBB2, FYN, CSF1R, PTK2, NTRK2, TYRO3, TEK, PAK1, ATM, DAPK1, PIM2 |
| protein autoubiquitination | biological_process | BRCA1 |
| protein catabolic process | biological_process | AKT1, MTOR, CTSD |
| protein complex assembly | biological_process | CCNB1, HMGA1, CD40, FAS, IL2RB, FGA, TP53, CD74, HES5, KIFAP3, IL1RAP, LAMC1 |
| protein complex localization | biological_process | BIRC5, FKBP4 |
| protein deacetylation | biological_process | HDAC1, SIRT1 |
| protein deamination | biological_process | LOXL1 |
| protein deglycosylation | biological_process | PARK7 |
| protein deneddylation | biological_process | COPS5 |
| protein dephosphorylation | biological_process | BCL2, ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR, ILKAP |
| protein destabilization | biological_process | SRC, ID1, PLK1, SIRT1, CDKN2A |
| protein deubiquitination | biological_process | UCHL1, COPS5 |
| protein export from nucleus | biological_process | GSK3B, TGFB1, CSE1L |
| protein folding | biological_process | HSPD1, TXN, HSP90AA1, CRYAB, APCS, FKBP4, FKBP5 |
| protein glycosylation | biological_process | DAD1, GBGT1 |
| protein heterooligomerization | biological_process | CTNNB1, BRAF, CTNNA1, CLDN3, Sep-09 |
| protein heterotetramerization | biological_process | INSR, ANXA2, HIST3H3 |
| protein heterotrimerization | biological_process | ADIPOQ |
| protein homooligomerization | biological_process | ANXA5, SLC6A4, HMOX1, FAS, CRYAB, CLDN3, BAX, ADIPOQ, AKR1C1, P2RX3, OLFM4 |
| protein homotetramerization | biological_process | GPX3, CAT, TP63 |
| protein homotrimerization | biological_process | MIF |
| protein import | biological_process | CLU, APOE |
| protein import into mitochondrial outer membrane | biological_process | HSPA4, HSP90AA1 |
| protein import into nucleus | biological_process | STAT3, CSE1L, IPO13 |
| protein import into nucleus, translocation | biological_process | BCL6, AKT1, AKR1C3, IFNG, TGFB1, TNF |
| protein insertion into membrane | biological_process | EGFR |
| protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological_process | BCL2L11, BAX |
| protein K6-linked ubiquitination | biological_process | BRCA1 |
| protein K63-linked ubiquitination | biological_process | CDKN2A |
| protein kinase B signaling | biological_process | CCL5, AKT1, CCL3, CD40, AXL, CCL2, PIK3CA, IGF1, TGFB1, TNF, IL1B, PTEN, GAS6, TYRO3, PAX2 |
| protein kinase C deactivation | biological_process | EDN1 |
| protein kinase C-activating G-protein coupled receptor signaling pathway | biological_process | F2R, EDNRA, EDN1, IL2, CRHR2 |
| protein localization | biological_process | BCL6, DRD2, TP53, KIFAP3 |
| protein localization to bicellular tight junction | biological_process | ACTN4 |
| protein localization to cell surface | biological_process | CTNNB1, ANGPT1 |
| protein localization to centrosome | biological_process | AURKA |
| protein localization to chromatin | biological_process | ESR1, PLK1, EZH2 |
| protein localization to chromosome, centromeric region | biological_process | RB1 |
| protein localization to cytoplasmic stress granule | biological_process | TIA1, YBX1 |
| protein localization to early endosome | biological_process | NRP1 |
| protein localization to microtubule | biological_process | GSK3B |
| protein localization to nucleus | biological_process | BMP4 |
| protein localization to plasma membrane | biological_process | CDH1, DPP6, FCER1G, RAC1, ADIPOQ |
| protein maturation | biological_process | HSPD1 |
| protein N-linked glycosylation via asparagine | biological_process | DAD1 |
| protein O-linked fucosylation | biological_process | THBS1 |
| protein O-linked glycosylation | biological_process | TET3, TET2, TET1 |
| protein oligomerization | biological_process | GJA1, SLC6A4, AR, LIPC, BAX, TEK, STOML2, NOD2, NOD1 |
| protein oxidation | biological_process | APOA1, APOA2, GPX1 |
| protein peptidyl-prolyl isomerization | biological_process | FKBP4, FKBP5 |
| protein phosphorylation | biological_process | GSK3B, FGFR1, SRC, CCND1, MET, WNT5A, MAPK1, FGFR2, IGFBP3, PIK3R1, KIT, AKT1, CCNB1, ERBB3, KDR, RASSF2, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, CCL2, PIK3CA, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, TGFB1, MAP3K7, IGF1R, PRKCB, BIRC5, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, CTSG, RUNX3, PLK1, TGFB2, PTK2, NTRK2, GAS6, TYRO3, TEK, HSF1, PAK1, SMAD2, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2, KSR1, CCL11 |
| protein polymerization | biological_process | FGA |
| protein polyubiquitination | biological_process | BCL2, PSMD9, PSMD10, TRIM36, CDKN2A, BLMH |
| protein processing | biological_process | CASP1, CASP3, CMA1, CTSG, PCSK5 |
| protein refolding | biological_process | HSPD1, HSPA6, HSP90AA1 |
| protein repair | biological_process | TXN |
| protein secretion | biological_process | SNCG |
| protein stabilization | biological_process | HSPD1, CLU, PIK3R1, RASSF2, CDKN1A, CHEK2, IGF1, HSP90AA1, APOA1, SMAD7, PTEN, PARK7, PIM2, CDKN2A, NAA15 |
| protein sumoylation | biological_process | PCNA, BRCA1, TP53, BIRC5, XRCC4, CDKN2A, PIAS3 |
| protein targeting to plasma membrane | biological_process | BSG, ANXA2, GAS6 |
| protein tetramerization | biological_process | CCL5, HLA-DRB1, IGF1R, TP53, CAT, TP63 |
| protein transmembrane transport | biological_process | AZGP1, MCL1 |
| protein transport | biological_process | PIK3R1, ACTN4, CCDC22, S100A13, CSE1L, IPO13 |
| protein transport within lipid bilayer | biological_process | ITGB1 |
| protein ubiquitination | biological_process | AKT1, BRCA1, BIRC5, SOCS3, CDC42, PLK1, NFE2L2, SIRT1 |
| protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological_process | CCNB1, AURKA, PLK1 |
| protein unfolding | biological_process | HSP90AA1 |
| protein-DNA complex assembly | biological_process | HNF1B |
| proteoglycan biosynthetic process | biological_process | IGF1, BMPR1B, XYLT2 |
| proteoglycan metabolic process | biological_process | HPSE |
| proteolysis | biological_process | MME, MMP13, DPP6, MMP9, CASP1, MBL2, ACE, CASP3, UCHL1, HGF, MMP7, MMP10, C4A, MMP14, CMA1, MMP11, MMP12, PLAT, LTF, C3, CAPN5, CTSB, PLAU, MMP1, CTSD, KLK3, MMP2, MMP3, CTSG, COPS5, PARK7, ADAM17, PCSK5, ADAM8, ADAM22, BLMH, TPSAB1, FOLH1, PAPPA, WFDC2, IHH, HTRA1, CPB2, MMP24, TPSB2, MST1 |
| proteolysis in other organism | biological_process | MAP2K7 |
| proteolysis involved in cellular protein catabolic process | biological_process | CTSB |
| proton transport | biological_process | ATP5A1, ATP5B |
| proximal/distal pattern formation | biological_process | CTNNB1, HOXA10, HOXA11, GREM1, TP63 |
| pulmonary artery endothelial tube morphogenesis | biological_process | BMP4 |
| pulmonary artery morphogenesis | biological_process | JAG1 |
| pulmonary myocardium development | biological_process | SEMA3C |
| pulmonary valve morphogenesis | biological_process | NOTCH1, HEY1, JAG1 |
| purine nucleobase metabolic process | biological_process | IL1B |
| purine nucleoside metabolic process | biological_process | PNP |
| purine nucleotide catabolic process | biological_process | XDH, PNP, GPX1, CAT |
| purine nucleotide metabolic process | biological_process | NME1, FHIT |
| purine nucleotide salvage | biological_process | ADA |
| purine ribonucleoside monophosphate biosynthetic process | biological_process | ADA |
| purine-containing compound salvage | biological_process | PNP, ADA |
| purinergic nucleotide receptor signaling pathway | biological_process | P2RX3 |
| pyramidal neuron development | biological_process | FGFR2, ATP7A |
| pyrimidine dimer repair by nucleotide-excision repair | biological_process | SIRT1 |
| pyrimidine nucleobase metabolic process | biological_process | TYMP |
| pyrimidine nucleoside catabolic process | biological_process | TYMP |
| pyrimidine nucleoside metabolic process | biological_process | TYMP |
| pyrimidine nucleoside salvage | biological_process | TYMP |
| pyrimidine nucleotide metabolic process | biological_process | NME1, TYMP |
| pyroptosis | biological_process | CASP1 |
| pyruvate metabolic process | biological_process | BSG |
| Rac protein signal transduction | biological_process | AIF1 |
| radial glial cell differentiation | biological_process | STAT3 |
| radial pattern formation | biological_process | NR2F2 |
| Ras protein signal transduction | biological_process | FGF2, DNMT1, SHC1, CDKN1A, CDKN2A, IGF1, JUN, TP53, RB1, NRAS, KRAS, PARK7, KSR1 |
| re-entry into mitotic cell cycle | biological_process | GSK3B, CCND1 |
| reactive oxygen species metabolic process | biological_process | BCL2, NDUFS1, SOD1, CYR61, PAX2 |
| receptor biosynthetic process | biological_process | IL10, TNF |
| receptor catabolic process | biological_process | TGFB1 |
| receptor clustering | biological_process | ITGB2 |
| receptor internalization | biological_process | CD36, CXCL8, CXCR1, CXCR2, FCER1G, ADM, PTGER3, ITGB1, ITGB2, LILRB1 |
| receptor-mediated endocytosis | biological_process | CETP, FOLR1, IGF2R, CD36, SPARC, SAA1, MRC1, HSP90AA1, APOA1, APOE, HP, HPX, LOXL4, SCARB1, CXCL16 |
| receptor-mediated virion attachment to host cell | biological_process | ICAM1, GAS6 |
| reciprocal meiotic recombination | biological_process | MSH2, MSH6, MLH1, XRCC3, ATM |
| recognition of apoptotic cell | biological_process | SCARB1 |
| regulated exocytosis | biological_process | CRHBP |
| regulation of acrosome reaction | biological_process | SPINK1 |
| regulation of actin cytoskeleton organization | biological_process | CRK, MTOR, PDGFA, TGFB2, PAK1, RHOA |
| regulation of actin cytoskeleton reorganization | biological_process | PDGFRA, TGFB1, CSF1R |
| regulation of actin filament polymerization | biological_process | LATS1 |
| regulation of actin polymerization or depolymerization | biological_process | CXCL12 |
| regulation of activated T cell proliferation | biological_process | IDO1 |
| regulation of activin receptor signaling pathway | biological_process | SMAD7 |
| regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway | biological_process | CRHR1 |
| regulation of aerobic respiration | biological_process | HIF1A |
| regulation of androgen receptor signaling pathway | biological_process | PARK7 |
| regulation of angiogenesis | biological_process | FGF2, LEP, CTNNB1, ID1, HMOX1, EFNA1, ERBB2, CXCL13, KRT1, IL6, PROK1 |
| regulation of angiotensin metabolic process | biological_process | ACE |
| regulation of animal organ formation | biological_process | WT1 |
| regulation of anion transmembrane transport | biological_process | CLCN3 |
| regulation of anion transport | biological_process | CA2, STC1 |
| regulation of apoptotic cell clearance | biological_process | ITGAV |
| regulation of apoptotic DNA fragmentation | biological_process | CDKN2A |
| regulation of apoptotic process | biological_process | BCL2, EGR1, BCL6, TNFRSF1A, IGF2R, IGFBP3, CTNNB1, BRCA1, CASP1, NME1, TNFRSF1B, AGTR2, LGALS1, FAS, BMP6, FLT3, ESR1, TGFB1, ACTN4, INHA, TP53, BIRC5, FYN, SGK1, TNFRSF11B, MSTN, BCL2L11, GDF9, CTSB, TNFRSF21, IL6, TGFB2, BCL2L1, BAX, NOD2, MCL1, ATM, NOD1, DAPK1, TP63, OLFM4, GDF15, SRA1 |
| regulation of appetite | biological_process | NPY |
| regulation of asymmetric cell division | biological_process | POU5F1 |
| regulation of atrial cardiac muscle cell membrane depolarization | biological_process | GJA1 |
| regulation of attachment of spindle microtubules to kinetochore | biological_process | CDC42 |
| regulation of auditory receptor cell differentiation | biological_process | NOTCH1, HES5 |
| regulation of autophagy | biological_process | BCL2, HMGB1, CASP1, HSPB1, PSAP, ATM, DAPK1 |
| regulation of axon diameter | biological_process | WNT7A |
| regulation of axon extension | biological_process | GSK3B, APOE, DPYSL2, OLFM1 |
| regulation of axon extension involved in axon guidance | biological_process | NRP1, SEMA3A |
| regulation of axon regeneration | biological_process | BRAF, PTEN |
| regulation of axonogenesis | biological_process | GSK3B, EFNA1, WNT7A |
| regulation of B cell apoptotic process | biological_process | PTEN |
| regulation of B cell proliferation | biological_process | AHR |
| regulation of B cell receptor signaling pathway | biological_process | PTPN22 |
| regulation of behavior | biological_process | MDK |
| regulation of beta-amyloid clearance | biological_process | CLU, APOE |
| regulation of bicellular tight junction assembly | biological_process | GJA1, SNAI1 |
| regulation of bile acid biosynthetic process | biological_process | SIRT1 |
| regulation of binding | biological_process | TGFB1, SMAD3, SMAD2, SMAD4 |
| regulation of blood coagulation | biological_process | F2R, F2RL1 |
| regulation of blood pressure | biological_process | PPARG, LEP, ACE, AGTR2, EDNRA, HMOX1, TACR1, PTGS1, NOS3, PTGS2, SOD1, SGK1, EDN1, NRG1, NPY |
| regulation of blood vessel diameter by renin-angiotensin | biological_process | AGTR1 |
| regulation of blood vessel endothelial cell migration | biological_process | EFNA1 |
| regulation of blood vessel remodeling | biological_process | FLT4, TGFB1 |
| regulation of blood vessel size | biological_process | GCLC, NOS3, EDN1 |
| regulation of blood volume by renal aldosterone | biological_process | HSD11B2 |
| regulation of BMP signaling pathway | biological_process | ITGA3 |
| regulation of bone mineralization | biological_process | GJA1, AHSG, TWIST1 |
| regulation of bone remodeling | biological_process | GJA1, LEP, LEPR |
| regulation of bone resorption | biological_process | SRC, ITGB3, CSF1R, IL20RA |
| regulation of branch elongation involved in ureteric bud branching | biological_process | HNF1B |
| regulation of branching involved in mammary gland duct morphogenesis | biological_process | WNT5A, TGFB1 |
| regulation of branching involved in prostate gland morphogenesis | biological_process | BMP4, FGFR2, ESR1 |
| regulation of branching involved in salivary gland morphogenesis | biological_process | TNF |
| regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling | biological_process | PDGFA |
| regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling | biological_process | NTN4 |
| regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling | biological_process | FGFR1, HGF |
| regulation of brown fat cell differentiation | biological_process | LEP, MTOR, SIRT1 |
| regulation of calcidiol 1-monooxygenase activity | biological_process | VDR |
| regulation of calcium ion import | biological_process | CTNNB1, EGF |
| regulation of calcium ion transport | biological_process | BCL2, GJA1, CXCL12, IGF1, CXCR4 |
| regulation of cAMP metabolic process | biological_process | DRD2 |
| regulation of cAMP-dependent protein kinase activity | biological_process | MST1 |
| regulation of canonical Wnt signaling pathway | biological_process | YAP1, FOLR1 |
| regulation of carbohydrate metabolic process | biological_process | MTOR |
| regulation of carbohydrate utilization | biological_process | MTOR |
| regulation of cardiac muscle cell contraction | biological_process | STC1 |
| regulation of cardiac muscle contraction | biological_process | SMAD7 |
| regulation of cardioblast proliferation | biological_process | NOTCH1 |
| regulation of cartilage development | biological_process | BMP4, TGFB1 |
| regulation of catalytic activity | biological_process | BCL2, HSP90AA1, SGK1, CTSB, HIF1A, DNMT3L |
| regulation of caveolin-mediated endocytosis | biological_process | SRC |
| regulation of CD4-positive, alpha-beta T cell activation | biological_process | AGER |
| regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | GATA3 |
| regulation of Cdc42 protein signal transduction | biological_process | APOA1, APOE |
| regulation of cell adhesion | biological_process | CXCL8, ENG, PRLR, LAMA1, LAMA5, ICAM1, IL18 |
| regulation of cell adhesion mediated by integrin | biological_process | EFNA1, PLAU, PTK2 |
| regulation of cell cycle | biological_process | BCL2, SRC, CCND1, STAT3, LEP, CCNB1, CDKN1A, ITGB1, JUN, INHA, SGK1, RB1, COPS5, PTEN, PLK1, BAX, PLCB1, ATM, TRIM36 |
| regulation of cell cycle checkpoint | biological_process | AKT1 |
| regulation of cell cycle G2/M phase transition | biological_process | TP53, PLK1 |
| regulation of cell cycle process | biological_process | HMGA2 |
| regulation of cell death | biological_process | JUN, CRYAB |
| regulation of cell differentiation | biological_process | FGFR1, BMP4, CTNNB1, LIF, SOCS3, SPRY2, RUNX3, NRG1, HES5, IHH, SPOCK2, NANOG |
| regulation of cell fate commitment | biological_process | BMP4, FGFR2 |
| regulation of cell growth | biological_process | IGFBP2, IGFBP3, AGTR1, IGFBP5, IGFBP1, IGFBP4, SGK1, CYR61, IGFBP7, HTRA1 |
| regulation of cell migration | biological_process | AKT1, NOTCH1, LAMA1, MMP10, ITGB3, TGFB1, SGK1, LAMA5, RAC1, CXCR4, JAG1, SST, RHOA |
| regulation of cell morphogenesis | biological_process | CFL1, SPARC, RAC1 |
| regulation of cell motility | biological_process | ERBB3, EGFR, ERBB2, EGF, NRG1, RHOA |
| regulation of cell projection assembly | biological_process | SRC, CCL19 |
| regulation of cell proliferation | biological_process | FGFR1, SRC, YAP1, BCL6, NOS2, DNMT1, PLA2G4A, TNFRSF1A, KIT, MIF, SHC1, CTNNB1, BRCA1, ERBB3, CDKN1B, NOTCH1, PLCD1, TNFRSF1B, CD40, BRAF, CTNNA1, AGTR1, ENG, JAK1, SPARC, TYK2, FAS, STAT6, CXCL2, PTGS1, TNC, PTGS2, PTGER2, IGF1, EGFR, JUN, TGFB1, ANXA1, LGR5, INHA, TNF, CXCL10, FYN, SGK1, TNFRSF11B, NR5A2, WNT7A, LAMA5, SPRY2, CXCL13, TNFRSF21, PRDM1, PLAU, CSF2, IL6, PTK2, HIF1A, FOXO1, GHRL, EZH2, SIRT1, SMAD4, JAG1, CXCL6, PLCD3, MBD2 |
| regulation of cell shape | biological_process | VEGFA, KIT, CCL3, KDR, CCL2, PTN, FN1, ANXA1, FYN, ITGB2, ICAM1, IL6, CSF1R, PTK2, S100A13, CCL7, CCL11 |
| regulation of cell size | biological_process | RAC1 |
| regulation of cell-cell adhesion | biological_process | SRC, ADAM8, WNT4 |
| regulation of cell-cell adhesion mediated by integrin | biological_process | ADA |
| regulation of cell-matrix adhesion | biological_process | BCL2 |
| regulation of cellular amino acid metabolic process | biological_process | PSMD9, PSMD10 |
| regulation of cellular component size | biological_process | PTEN |
| regulation of cellular extravasation | biological_process | SELP |
| regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter | biological_process | PPARA |
| regulation of cellular localization | biological_process | PTEN |
| regulation of cellular protein localization | biological_process | WNT5A |
| regulation of cellular respiration | biological_process | NOS2, PIK3CA |
| regulation of cellular response to drug | biological_process | HMGA2 |
| regulation of cellular response to heat | biological_process | GSK3B, MAPK1, MTOR, HSP90AA1, CRYAB, HSF1, FKBP4, SIRT1, ATM |
| regulation of cellular response to hypoxia | biological_process | HIF1A |
| regulation of cellular response to X-ray | biological_process | GATA3 |
| regulation of centriole-centriole cohesion | biological_process | CTNNB1 |
| regulation of centromere complex assembly | biological_process | RB1 |
| regulation of centromeric sister chromatid cohesion | biological_process | CTNNB1 |
| regulation of centrosome cycle | biological_process | AURKA |
| regulation of centrosome duplication | biological_process | XRCC3 |
| regulation of cGMP metabolic process | biological_process | VEGFA, THBS1 |
| regulation of chemotaxis | biological_process | PDGFRA, CXCR4 |
| regulation of chloride transport | biological_process | CA2 |
| regulation of cholesterol efflux | biological_process | CETP |
| regulation of cholesterol transporter activity | biological_process | PPARG |
| regulation of chondrocyte differentiation | biological_process | HOXA11, MAF |
| regulation of chromosome condensation | biological_process | CCNB1 |
| regulation of chronic inflammatory response | biological_process | CCL5 |
| regulation of circadian rhythm | biological_process | PPARG, PPARA, EZH2, ID2, KLF10 |
| regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | IL6 |
| regulation of circadian sleep/wake cycle, sleep | biological_process | PTGDS, ADA |
| regulation of circadian sleep/wake cycle, wakefulness | biological_process | PTGER4, PTGER3 |
| regulation of cohesin loading | biological_process | RB1 |
| regulation of collagen catabolic process | biological_process | ITGB1 |
| regulation of complement activation | biological_process | C4A, C3, C5, C4BPA, C1QBP |
| regulation of complement-dependent cytotoxicity | biological_process | IL10, IL11, TGFB2 |
| regulation of core promoter binding | biological_process | CTNNB1 |
| regulation of corticosterone secretion | biological_process | CRHR1 |
| regulation of corticotropin secretion | biological_process | CRHBP |
| regulation of cyclin-dependent protein serine/threonine kinase activity | biological_process | CDKN1B, CDKN1A, DIRAS3, PTEN |
| regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | FAS, SOX2, NGF, BAX, TP63 |
| regulation of cytokine biosynthetic process | biological_process | GATA3, IL12B |
| regulation of cytokine production | biological_process | LTF, CD83 |
| regulation of cytokine production involved in inflammatory response | biological_process | NOS2, LEP |
| regulation of cytokine secretion | biological_process | TLR2, TLR4, TLR9 |
| regulation of cytokinesis | biological_process | BRCA2, AURKA |
| regulation of cytoskeleton organization | biological_process | MAPK1, STMN1, PTK2 |
| regulation of cytosolic calcium ion concentration | biological_process | GPER1 |
| regulation of defense response to bacterium | biological_process | FOXP1 |
| regulation of defense response to virus | biological_process | IL27 |
| regulation of defense response to virus by host | biological_process | IL15 |
| regulation of defense response to virus by virus | biological_process | CD4, FYN, RAC1 |
| regulation of dendrite development | biological_process | NTRK2 |
| regulation of dendrite morphogenesis | biological_process | GSK3B |
| regulation of dendritic cell cytokine production | biological_process | TLR4, TLR3 |
| regulation of dendritic cell dendrite assembly | biological_process | CCR7 |
| regulation of dendritic cell differentiation | biological_process | HLA-B |
| regulation of dendritic spine morphogenesis | biological_process | CFL1 |
| regulation of developmental pigmentation | biological_process | BCL2, KIT, BCL2L11 |
| regulation of developmental process | biological_process | NOTCH1 |
| regulation of digestive system process | biological_process | OXTR |
| regulation of DNA binding | biological_process | TGFB1 |
| regulation of DNA biosynthetic process | biological_process | CDKN1A, PDGFA |
| regulation of DNA methylation | biological_process | BRCA1 |
| regulation of DNA replication | biological_process | PCNA, EHMT2 |
| regulation of dopamine secretion | biological_process | DRD2, SNCG |
| regulation of dopamine uptake involved in synaptic transmission | biological_process | DRD2 |
| regulation of dopaminergic neuron differentiation | biological_process | DKK1 |
| regulation of early endosome to late endosome transport | biological_process | SRC, MAPK1 |
| regulation of embryonic development | biological_process | LAMA1, INSR, LAMA5, NFE2L2 |
| regulation of endodeoxyribonuclease activity | biological_process | SIRT1 |
| regulation of endodermal cell fate specification | biological_process | HNF1B, DKK1 |
| regulation of endothelial cell apoptotic process | biological_process | TEK |
| regulation of endothelial cell chemotaxis to fibroblast growth factor | biological_process | FGF2, FGF1 |
| regulation of endothelial cell migration | biological_process | PTK2 |
| regulation of endothelial cell proliferation | biological_process | LEP, ANGPT1 |
| regulation of endothelial tube morphogenesis | biological_process | FGF1, CXCL10, FOXP1 |
| regulation of energy homeostasis | biological_process | CD36, LEPR, FOXO1 |
| regulation of engulfment of apoptotic cell | biological_process | ALOX15 |
| regulation of epidermal cell division | biological_process | TP63 |
| regulation of epidermal growth factor-activated receptor activity | biological_process | SHC1 |
| regulation of epithelial cell differentiation | biological_process | XDH, CTNNB1, PRLR |
| regulation of epithelial cell migration | biological_process | SRC, PTK2 |
| regulation of epithelial cell proliferation | biological_process | NOTCH1, EDNRA, SMAD3, HES5 |
| regulation of epithelial cell proliferation involved in prostate gland development | biological_process | NOTCH1 |
| regulation of epithelial to mesenchymal transition | biological_process | GREM1, SMAD7 |
| regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | TGFB1 |
| regulation of ERK1 and ERK2 cascade | biological_process | BMP4, FGFR2, GSTP1, FN1, ERBB2, CYR61, CRHR2 |
| regulation of establishment of cell polarity | biological_process | GATA3 |
| regulation of establishment of endothelial barrier | biological_process | TNFRSF1A, TNF, IL1B |
| regulation of establishment of protein localization to plasma membrane | biological_process | PIK3R1, AR |
| regulation of establishment or maintenance of cell polarity | biological_process | TEK |
| regulation of euchromatin binding | biological_process | CTNNB1 |
| regulation of extracellular matrix assembly | biological_process | NOTCH1 |
| regulation of extracellular matrix organization | biological_process | TGFB2 |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological_process | FGFR1 |
| regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological_process | LGALS3, TNFSF10, FASLG, FAS |
| regulation of fat cell differentiation | biological_process | PPARG, LEP |
| regulation of fatty acid beta-oxidation | biological_process | MTOR |
| regulation of fatty acid metabolic process | biological_process | PPARA |
| regulation of feeding behavior | biological_process | STAT3, LEPR |
| regulation of female gonad development | biological_process | INSR |
| regulation of fertilization | biological_process | PLCB1 |
| regulation of fibroblast growth factor receptor signaling pathway | biological_process | FGFR2 |
| regulation of fibroblast migration | biological_process | SDC4, RAC1 |
| regulation of fibroblast proliferation | biological_process | CTNNB1 |
| regulation of filopodium assembly | biological_process | CDC42 |
| regulation of flagellated sperm motility | biological_process | ANXA5 |
| regulation of focal adhesion assembly | biological_process | GREM1, PTK2 |
| regulation of follicle-stimulating hormone secretion | biological_process | INHBA |
| regulation of forebrain neuron differentiation | biological_process | GATA2 |
| regulation of G-protein coupled receptor protein signaling pathway | biological_process | ITGB1, PLCB1 |
| regulation of G1/S transition of mitotic cell cycle | biological_process | CCND1, ID2 |
| regulation of G2/M transition of mitotic cell cycle | biological_process | CDKN2A |
| regulation of gastric acid secretion | biological_process | SGK1 |
| regulation of gastrulation | biological_process | NODAL |
| regulation of gene expression | biological_process | BCL2, FGFR1, BMP4, DNMT1, IL10, CTNNB1, AHR, NOTCH1, FAS, HOXA10, PIK3CA, HOXA11, SOX2, IGF1, TGFB1, APOE, MYC, CYP1A2, CSF2, DNMT3A, HIF1A, PPARA, POU5F1, EZH2, DNMT3B, EMX2, GATA6, NANOG |
| regulation of gene expression by genetic imprinting | biological_process | GSK3B, BRCA1, DIRAS3, IGF2, DNMT3A, DNMT3L |
| regulation of gene expression, epigenetic | biological_process | GPX1 |
| regulation of genetic imprinting | biological_process | PIK3CA |
| regulation of germinal center formation | biological_process | BCL6 |
| regulation of gliogenesis | biological_process | EZH2 |
| regulation of glomerular mesangial cell proliferation | biological_process | PDGFA |
| regulation of gluconeogenesis | biological_process | LEP |
| regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter | biological_process | FOXO1 |
| regulation of glucose metabolic process | biological_process | IGFBP3, IGFBP5, IGFBP4, ADIPOQ, SIRT1, ADIPOR1 |
| regulation of glycogen biosynthetic process | biological_process | AKT1, MTOR |
| regulation of glycolytic process | biological_process | HIF1A |
| regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter | biological_process | PPARA |
| regulation of glycoprotein biosynthetic process | biological_process | BCL2 |
| regulation of Golgi inheritance | biological_process | MAPK1 |
| regulation of Golgi organization | biological_process | STX5 |
| regulation of granulocyte macrophage colony-stimulating factor biosynthetic process | biological_process | IL17F |
| regulation of growth | biological_process | HMGA2, IGFBP2, IGFBP3, SHC1, IGFBP5, IGFBP4, IFNG, SOCS3, GAS6 |
| regulation of GTPase activity | biological_process | CRK, BCL6, MTOR, SOD1, PTK2, NTRK2 |
| regulation of hair cycle | biological_process | CLOCK |
| regulation of hair cycle by canonical Wnt signaling pathway | biological_process | CDH3 |
| regulation of hair follicle development | biological_process | HPSE, SMAD4 |
| regulation of heart contraction | biological_process | GJA1 |
| regulation of heart induction by regulation of canonical Wnt signaling pathway | biological_process | POU5F1 |
| regulation of heart rate | biological_process | GJA1, DRD2, SEMA3A |
| regulation of hematopoietic stem cell proliferation | biological_process | ACE |
| regulation of hepatocyte proliferation | biological_process | IFNG, PLAU |
| regulation of histone acetylation | biological_process | GATA2 |
| regulation of histone H3-K27 methylation | biological_process | GATA3 |
| regulation of histone H3-K4 methylation | biological_process | GATA3 |
| regulation of histone methylation | biological_process | MTHFR |
| regulation of homophilic cell adhesion | biological_process | PTPRR |
| regulation of hormone secretion | biological_process | ANXA1 |
| regulation of humoral immune response | biological_process | CXCL13 |
| regulation of hydrogen peroxide metabolic process | biological_process | INSR, RAC1 |
| regulation of I-kappaB kinase/NF-kappaB signaling | biological_process | TNF, HSPB1, IL1B, F2RL1, ANGPT1 |
| regulation of immune response | biological_process | BCL6, CD40LG, CD40, HLA-C, HLA-E, KLRC1, VCAM1, HLA-G, KIR2DL1, KIR2DL3, FCER1G, HLA-A, KIR3DL1, ITGB1, IFNG, C3, NCR1, ITGB2, HLA-B, ICAM1, IL4, SMAD3, KLRD1, MICA, MICB, TBX21, CD1A, KLRK1, LILRB1 |
| regulation of immunoglobulin production | biological_process | FOXP3 |
| regulation of immunoglobulin secretion | biological_process | CD40LG, CD40, TNF |
| regulation of inflammatory response | biological_process | BCL6, CASP1, AGTR1, IL1R1, SELE, CMA1, PTGS2, ANXA1, AHSG, TLR4, IL4, RELA, PARK7, FOXP1, NOD2 |
| regulation of innate immune response | biological_process | PTPN22 |
| regulation of insulin secretion | biological_process | NOS2, CCL5, LEP, SSTR5, IFNG, CLOCK, TNF, IL1B |
| regulation of insulin-like growth factor receptor signaling pathway | biological_process | IGFBP2, IGFBP3, IGFBP1, IGFBP4 |
| regulation of integrin activation | biological_process | SELP |
| regulation of integrin-mediated signaling pathway | biological_process | TIMP1 |
| regulation of interferon-gamma production | biological_process | CCR7 |
| regulation of interferon-gamma-mediated signaling pathway | biological_process | JAK1, IFNG, SOCS3 |
| regulation of interleukin-1 beta production | biological_process | F2R |
| regulation of interleukin-1 beta secretion | biological_process | FOXP1, CCR7 |
| regulation of interleukin-1 production | biological_process | ANXA1 |
| regulation of interleukin-10 secretion | biological_process | HLA-DRB1 |
| regulation of interleukin-12 production | biological_process | HLA-B |
| regulation of interleukin-12 secretion | biological_process | FOXP1 |
| regulation of interleukin-2 biosynthetic process | biological_process | IL17F |
| regulation of interleukin-23 production | biological_process | TGFB1 |
| regulation of interleukin-4 production | biological_process | HLA-DRB1, LGALS9 |
| regulation of interleukin-5 production | biological_process | LGALS9 |
| regulation of interleukin-6 biosynthetic process | biological_process | IL17F |
| regulation of interleukin-6 production | biological_process | HLA-B |
| regulation of interleukin-8 biosynthetic process | biological_process | IL17F |
| regulation of interleukin-8 secretion | biological_process | CRP |
| regulation of intestinal cholesterol absorption | biological_process | LEP, APOA1, APOA2 |
| regulation of intracellular estrogen receptor signaling pathway | biological_process | SRC |
| regulation of intracellular pH | biological_process | ATP5B, CA2, SLC26A8 |
| regulation of ion transmembrane transport | biological_process | CLCN3 |
| regulation of IRE1-mediated unfolded protein response | biological_process | COPS5 |
| regulation of isotype switching | biological_process | IL10, IL4 |
| regulation of isotype switching to IgG isotypes | biological_process | FOXP3 |
| regulation of JNK cascade | biological_process | IGF1R, COPS5, F2RL1 |
| regulation of keratinocyte differentiation | biological_process | ERRFI1 |
| regulation of keratinocyte proliferation | biological_process | YAP1 |
| regulation of lateral mesodermal cell fate specification | biological_process | FGFR1 |
| regulation of leukocyte mediated cytotoxicity | biological_process | ICAM1 |
| regulation of leukocyte migration | biological_process | CXCR3, ANXA1 |
| regulation of lipid catabolic process | biological_process | RARRES2 |
| regulation of lipid kinase activity | biological_process | RB1 |
| regulation of lipid metabolic process | biological_process | PPARG, PSAP, ID2, IRS2, ADIPOR1 |
| regulation of lipid storage | biological_process | SIRT1 |
| regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter | biological_process | PPARA |
| regulation of lipoprotein lipid oxidation | biological_process | LEP |
| regulation of locomotion involved in locomotory behavior | biological_process | DRD2 |
| regulation of long-term neuronal synaptic plasticity | biological_process | DRD2, KRAS, SYP |
| regulation of lymphocyte differentiation | biological_process | FAS |
| regulation of macroautophagy | biological_process | CASP3, UCHL1 |
| regulation of macrophage activation | biological_process | MIF, CD74 |
| regulation of macrophage colony-stimulating factor production | biological_process | FOXP1 |
| regulation of macrophage derived foam cell differentiation | biological_process | CSF1 |
| regulation of macrophage migration inhibitory factor signaling pathway | biological_process | ANGPT1 |
| regulation of mammary gland epithelial cell proliferation | biological_process | GPX1, BAX |
| regulation of MAPK cascade | biological_process | INHBA, DRD2, ID1, BMP6, INHA, MSTN, GDF9, PSAP, GDF15, HRH4 |
| regulation of mast cell apoptotic process | biological_process | ADAM17 |
| regulation of membrane permeability | biological_process | MTOR |
| regulation of membrane potential | biological_process | SLC26A8 |
| regulation of memory T cell differentiation | biological_process | BCL6 |
| regulation of mesenchymal cell proliferation | biological_process | ZEB1 |
| regulation of mesenchymal stem cell differentiation | biological_process | PDGFRA |
| regulation of metabolic process | biological_process | LEP, NTRK2 |
| regulation of metanephric nephron tubule epithelial cell differentiation | biological_process | YAP1, LIF, PAX2 |
| regulation of metanephros size | biological_process | AGTR2, PAX2 |
| regulation of methylation-dependent chromatin silencing | biological_process | POU5F1 |
| regulation of microtubule polymerization or depolymerization | biological_process | STMN1 |
| regulation of microtubule-based process | biological_process | GSK3B, ERBB2 |
| regulation of mitochondrial depolarization | biological_process | GCLC |
| regulation of mitochondrial membrane permeability | biological_process | BCL2, STAT3, TP53, BCL2L1 |
| regulation of mitochondrial membrane permeability involved in apoptotic process | biological_process | BAX |
| regulation of mitochondrial membrane permeability involved in programmed necrotic cell death | biological_process | BAX |
| regulation of mitochondrial membrane potential | biological_process | BCL2, NDUFS1, SOD1, BCL2L1, PARK7, BAX |
| regulation of mitotic cell cycle | biological_process | CDKN1A, RB1, PLK1, SIRT1, PIM2, RPRM |
| regulation of mitotic cell cycle spindle assembly checkpoint | biological_process | CCNB1 |
| regulation of mitotic centrosome separation | biological_process | CEP85 |
| regulation of mitotic metaphase/anaphase transition | biological_process | PLK1 |
| regulation of mitotic nuclear division | biological_process | CDC42 |
| regulation of mitotic spindle assembly | biological_process | PLK1 |
| regulation of monocyte differentiation | biological_process | FOXP1 |
| regulation of morphogenesis of a branching structure | biological_process | BMP4, FGFR2 |
| regulation of mRNA splicing, via spliceosome | biological_process | TIA1 |
| regulation of mRNA stability | biological_process | APEX1, AKT1, PSMD9, HSPB1, PSMD10, SET, ELAVL1 |
| regulation of multicellular organism growth | biological_process | STAT3, FGFR2, PIK3CA, IGF1, SOD1, PRL |
| regulation of myelination | biological_process | AKT1, CTNNB1, MTOR, HES5 |
| regulation of myeloid cell apoptotic process | biological_process | PTEN |
| regulation of myeloid cell differentiation | biological_process | FAS |
| regulation of N-methyl-D-aspartate selective glutamate receptor activity | biological_process | OPRM1, CRHBP, CRH, DAPK1 |
| regulation of natural killer cell activation | biological_process | LEP |
| regulation of natural killer cell mediated cytotoxicity | biological_process | LEP, NCR1 |
| regulation of natural killer cell mediated immunity | biological_process | HLA-E |
| regulation of natural killer cell proliferation | biological_process | LEP, PTPN22 |
| regulation of necrotic cell death | biological_process | OLFM4 |
| regulation of nephron tubule epithelial cell differentiation | biological_process | GATA3, CTNNB1 |
| regulation of neural precursor cell proliferation | biological_process | FOXO1 |
| regulation of neural retina development | biological_process | DLL4 |
| regulation of neurogenesis | biological_process | YAP1, BCL6, CTNNB1, NOTCH1, HES5, EZH2, DLL4 |
| regulation of neuron apoptotic process | biological_process | GATA3, ESR1, GPX1, PARK7, BAX, ESR2, TP63 |
| regulation of neuron death | biological_process | CCL5, CLU, APOE |
| regulation of neuron differentiation | biological_process | NTF4, NGF, DPYSL2, YWHAH |
| regulation of neuron maturation | biological_process | RAC1 |
| regulation of neuron projection development | biological_process | GSK3B, GATA3, AKT1, PTEN, DPYSL2 |
| regulation of neuronal action potential | biological_process | IFNG |
| regulation of neuronal signal transduction | biological_process | CLU |
| regulation of neuronal synaptic plasticity | biological_process | GSK3B, STAR, APOE, SYP |
| regulation of neurotransmitter secretion | biological_process | SNCG, NTRK2 |
| regulation of neutrophil extravasation | biological_process | OLFM4 |
| regulation of NIK/NF-kappaB signaling | biological_process | RASSF2, PTPN22 |
| regulation of nitric-oxide synthase activity | biological_process | LEP, AKT1, NOS3, HSP90AA1, EGFR, IL1B |
| regulation of nitrogen utilization | biological_process | BCL2, BAX |
| regulation of norepinephrine secretion | biological_process | PTGER3 |
| regulation of Notch signaling pathway | biological_process | NOTCH1, IL6ST, POSTN |
| regulation of nucleic acid-templated transcription | biological_process | ACTN4, SRA1 |
| regulation of nucleotide-excision repair | biological_process | HMGB1 |
| regulation of odontogenesis of dentin-containing tooth | biological_process | BMP4 |
| regulation of oligodendrocyte differentiation | biological_process | TNFRSF21 |
| regulation of opioid receptor signaling pathway | biological_process | SYP |
| regulation of opsonization | biological_process | C4BPA |
| regulation of organ growth | biological_process | SOD1, LATS1, BCL2L11 |
| regulation of ossification | biological_process | PTGER4, CSF1 |
| regulation of osteoblast differentiation | biological_process | FGFR2, CTNNB1, RASSF2, PTK2 |
| regulation of osteoblast proliferation | biological_process | FGFR2, RHOA |
| regulation of osteoclast differentiation | biological_process | FSHR, CTNNB1, RASSF2, MTOR, TNF, FSHB |
| regulation of oxidative phosphorylation | biological_process | ATP7A |
| regulation of p38MAPK cascade | biological_process | HGF, LGALS9 |
| regulation of pathway-restricted SMAD protein phosphorylation | biological_process | BMP4 |
| regulation of peptidyl-tyrosine phosphorylation | biological_process | EFNA1, EGFR, PDGFA, ITGB2, EGF |
| regulation of peroxisome proliferator activated receptor signaling pathway | biological_process | ALOX15, SIRT1 |
| regulation of pH | biological_process | CLCN3, EDN1 |
| regulation of phagocytosis | biological_process | ITGAV, SCARB1, OLFM4 |
| regulation of phosphatidylcholine catabolic process | biological_process | SCARB1 |
| regulation of phosphatidylinositol 3-kinase activity | biological_process | PIK3R1 |
| regulation of phosphatidylinositol 3-kinase signaling | biological_process | FGFR1, FGF2, MAPK1, FGFR2, PIK3R1, KIT, AKT1, ERBB3, PDGFRA, KITLG, PIK3CA, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, NRG1, IRS2 |
| regulation of phosphoprotein phosphatase activity | biological_process | DRD2 |
| regulation of phosphorylation | biological_process | ENG, IL4 |
| regulation of plasma lipoprotein particle levels | biological_process | LIPC |
| regulation of platelet activation | biological_process | FCER1G |
| regulation of podosome assembly | biological_process | SRC |
| regulation of potassium ion transmembrane transport | biological_process | DPP6 |
| regulation of potassium ion transport | biological_process | DRD2 |
| regulation of primitive erythrocyte differentiation | biological_process | GATA2 |
| regulation of progesterone secretion | biological_process | GDF9 |
| regulation of programmed cell death | biological_process | BCL2, CXCR4 |
| regulation of pronephros size | biological_process | HNF1B |
| regulation of proteasomal protein catabolic process | biological_process | GPX1 |
| regulation of protein ADP-ribosylation | biological_process | KAT2B |
| regulation of protein binding | biological_process | SRC, PLK1, ANGPT1 |
| regulation of protein catabolic process | biological_process | CHEK2, CDC42 |
| regulation of protein complex assembly | biological_process | HSP90AA1, LATS1 |
| regulation of protein export from nucleus | biological_process | CDKN2A |
| regulation of protein heterodimerization activity | biological_process | BCL2, CDC42, NRG1, BAX |
| regulation of protein homodimerization activity | biological_process | BCL2, NRG1, BAX |
| regulation of protein import into nucleus | biological_process | BMP4, TGFB1 |
| regulation of protein import into nucleus, translocation | biological_process | TXN, CDKN1A, SIRT1, OGG1 |
| regulation of protein kinase A signaling | biological_process | FSHR |
| regulation of protein kinase activity | biological_process | HMGB1, MTOR, SOD1, CXCL10, CDC42 |
| regulation of protein kinase B signaling | biological_process | MTOR, NTRK2 |
| regulation of protein localization | biological_process | BCL2, WNT5A, AKT1 |
| regulation of protein localization to cell surface | biological_process | CTNNB1, EGF |
| regulation of protein localization to nucleus | biological_process | LEP |
| regulation of protein metabolic process | biological_process | HPX, CDC42 |
| regulation of protein phosphatase type 2A activity | biological_process | SET |
| regulation of protein phosphorylation | biological_process | LEP, FN1, APOA1, TNF, SOCS3, PTK2, EZH2 |
| regulation of protein secretion | biological_process | SAA1, TNF |
| regulation of protein serine/threonine kinase activity | biological_process | SIRT1 |
| regulation of protein stability | biological_process | BCL2, MAPK1, AURKA, APOA2, TERT, KRAS, TF, CDC42, PTEN, CDKN2A |
| regulation of protein sumoylation | biological_process | EGR1 |
| regulation of protein targeting to mitochondrion | biological_process | CDKN2A |
| regulation of protein ubiquitination | biological_process | HSP90AA1 |
| regulation of proteolysis | biological_process | PLAUR |
| regulation of proton transport | biological_process | IL13, IL4 |
| regulation of Rac protein signal transduction | biological_process | CRK |
| regulation of Rap protein signal transduction | biological_process | TIMP2 |
| regulation of reactive oxygen species metabolic process | biological_process | TNF, FOXO1, CYP1B1 |
| regulation of receptor activity | biological_process | SERPINE1, PLAU |
| regulation of receptor internalization | biological_process | DKK1 |
| regulation of regulatory T cell differentiation | biological_process | TGFB1 |
| regulation of removal of superoxide radicals | biological_process | CD36, NFE2L2 |
| regulation of renal output by angiotensin | biological_process | ACE |
| regulation of renal sodium excretion | biological_process | AGTR1 |
| regulation of respiratory burst | biological_process | RAC1 |
| regulation of response to DNA damage stimulus | biological_process | MCL1 |
| regulation of response to food | biological_process | MTOR, GHRL |
| regulation of restriction endodeoxyribonuclease activity | biological_process | HMGB1 |
| regulation of retinal cell programmed cell death | biological_process | CNTF |
| regulation of retinal ganglion cell axon guidance | biological_process | VEGFA, NRP1 |
| regulation of retinoic acid receptor signaling pathway | biological_process | AKR1C3 |
| regulation of Rho protein signal transduction | biological_process | KALRN |
| regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological_process | LIF |
| regulation of ruffle assembly | biological_process | ICAM1 |
| regulation of secondary heart field cardioblast proliferation | biological_process | CTNNB1 |
| regulation of sensory perception of pain | biological_process | FGFR1, F2R, IL10, OPRM1, CCL3, COMT, EDN1 |
| regulation of sequence-specific DNA binding transcription factor activity | biological_process | MAPK1, ATF2, HMOX1, JUN, SGK1, FOS |
| regulation of serotonin secretion | biological_process | CRH |
| regulation of short-term neuronal synaptic plasticity | biological_process | SYP |
| regulation of signal transduction | biological_process | TDGF1, BIRC5, SPRY2, NODAL |
| regulation of signal transduction by p53 class mediator | biological_process | AKT1, BRCA1, CHEK2, AURKA, TP53, HDAC2, HDAC1, ATM, EHMT2, TP63 |
| regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological_process | CXCL8 |
| regulation of skeletal muscle satellite cell proliferation | biological_process | ANGPT1 |
| regulation of SMAD protein import into nucleus | biological_process | TGFB1 |
| regulation of small GTPase mediated signal transduction | biological_process | RHOC, A2M, KALRN, CDC42, RAC1, RHOA |
| regulation of smooth muscle cell apoptotic process | biological_process | SIRT1 |
| regulation of smooth muscle cell differentiation | biological_process | BMP4, FGFR2, ZEB1 |
| regulation of smooth muscle cell migration | biological_process | ACE, TACR1, PDGFA, PLAU |
| regulation of smooth muscle cell proliferation | biological_process | BMP4, CTNNB1, TACR1 |
| regulation of smooth muscle cell-matrix adhesion | biological_process | PLAU |
| regulation of smooth muscle contraction | biological_process | FLT1 |
| regulation of smoothened signaling pathway | biological_process | FGFR2 |
| regulation of sodium ion transmembrane transporter activity | biological_process | YWHAH |
| regulation of sodium ion transport | biological_process | DRD2, NOS3, TGFB1, YWHAH |
| regulation of somitogenesis | biological_process | CDX1, NOTCH1 |
| regulation of stem cell population maintenance | biological_process | HMGA2, ELAVL1, NODAL |
| regulation of stem cell proliferation | biological_process | FGFR1, YAP1 |
| regulation of steroid biosynthetic process | biological_process | LEP, STAR, NR5A1 |
| regulation of store-operated calcium entry | biological_process | SPINK1 |
| regulation of stress fiber assembly | biological_process | PIK3R1, PTGER4 |
| regulation of stress-activated MAPK cascade | biological_process | MAPK1, GSTP1, GREM1 |
| regulation of striated muscle tissue development | biological_process | TGFB1, SMAD3 |
| regulation of substrate adhesion-dependent cell spreading | biological_process | PTK2 |
| regulation of supramolecular fiber organization | biological_process | PARK7 |
| regulation of synapse assembly | biological_process | NECTIN1 |
| regulation of synapse organization | biological_process | DKK1 |
| regulation of synapse structural plasticity | biological_process | DRD2 |
| regulation of synaptic plasticity | biological_process | NCAM1, YWHAH, P2RX3 |
| regulation of synaptic transmission, GABAergic | biological_process | DRD2, KRAS, PTEN |
| regulation of synaptic transmission, glutamatergic | biological_process | DKK1, UCN |
| regulation of synaptic vesicle clustering | biological_process | PCDH17 |
| regulation of systemic arterial blood pressure | biological_process | PLCB3, POSTN |
| regulation of systemic arterial blood pressure by circulatory renin-angiotensin | biological_process | AGTR2 |
| regulation of systemic arterial blood pressure by endothelin | biological_process | NOS3, EDN1 |
| regulation of systemic arterial blood pressure by renin-angiotensin | biological_process | ACE, AGTR1 |
| regulation of systemic arterial blood pressure by vasopressin | biological_process | OXTR |
| regulation of T cell activation | biological_process | CCL5, CD4, IL20RB |
| regulation of T cell anergy | biological_process | HLA-B, FOXP3 |
| regulation of T cell apoptotic process | biological_process | LGALS3 |
| regulation of T cell chemotaxis | biological_process | CXCL10 |
| regulation of T cell differentiation | biological_process | IL15, ADA |
| regulation of T cell differentiation in thymus | biological_process | ZEB1, SOD1 |
| regulation of T cell homeostatic proliferation | biological_process | IL2RA, IL2 |
| regulation of T cell mediated cytotoxicity | biological_process | AGER |
| regulation of T cell mediated immune response to tumor cell | biological_process | HMGB1 |
| regulation of T cell proliferation | biological_process | LGALS3, CTNNB1, IL27 |
| regulation of T cell receptor signaling pathway | biological_process | PTPN22 |
| regulation of T cell tolerance induction | biological_process | IL2RA |
| regulation of T-helper 1 cell differentiation | biological_process | IL27 |
| regulation of tau-protein kinase activity | biological_process | HGF, APOE |
| regulation of telomerase activity | biological_process | ATM |
| regulation of telomere maintenance | biological_process | MYC |
| regulation of testosterone biosynthetic process | biological_process | AKR1C3 |
| regulation of the force of heart contraction | biological_process | ADM, IFNG |
| regulation of the force of heart contraction by chemical signal | biological_process | NOS3 |
| regulation of thymocyte apoptotic process | biological_process | HIF1A |
| regulation of tolerance induction | biological_process | HMGB1 |
| regulation of TRAIL receptor biosynthetic process | biological_process | PARK7 |
| regulation of transcription factor import into nucleus | biological_process | AGTR2 |
| regulation of transcription from RNA polymerase II promoter | biological_process | CRK, GATA3, INHBA, VEGFA, BCL6, STAT3, NR2F2, PPARG, HMGB1, CTNNB1, ATF2, BRCA1, NFKB1, AHR, NOTCH1, ANXA4, USF1, STAT6, WT1, ZEB1, CLOCK, PRKCB, FSTL3, RB1, ARID1A, SOX15, SNAI1, FOS, RUNX3, SMAD3, FOXP1, FOXO1, NR5A1, NFKB2, FOXP3, EZH2, SMAD4, USF2, KLF9, MAF |
| regulation of transcription from RNA polymerase II promoter by glucose | biological_process | USF1, USF2 |
| regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological_process | EGR1, VEGFA, ARNT, HIF1A |
| regulation of transcription from RNA polymerase II promoter in response to iron | biological_process | HMOX1 |
| regulation of transcription from RNA polymerase II promoter in response to oxidative stress | biological_process | HMOX1, ARNT, HIF1A |
| regulation of transcription from RNA polymerase II promoter in response to stress | biological_process | MUC1 |
| regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | biological_process | NOTCH1 |
| regulation of transcription from RNA polymerase III promoter | biological_process | BRCA1 |
| regulation of transcription involved in cell fate commitment | biological_process | PPARG, CHD5 |
| regulation of transcription involved in G1/S transition of mitotic cell cycle | biological_process | PCNA, RB1, KLF11 |
| regulation of transcription involved in lymphatic endothelial cell fate commitment | biological_process | NR2F2 |
| regulation of transcription, DNA-templated | biological_process | FGFR1, EGR1, TXN, GATA3, YAP1, CCND1, BCL6, STAT3, NR2F2, DNMT1, CDX1, HMGA2, PPARG, MAPK1, APEX1, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, AHR, NOTCH1, ID1, FASLG, VDR, ENG, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ZEB1, CHEK2, ESR1, INSR, JUN, IFNG, CLOCK, MAP3K7, PRKCB, FSTL3, LTF, TP53, SUV39H1, MYC, BIRC5, ENO1, ERBB2, SMAD7, MEIS1, NR5A2, RB1, ARID1A, SOX15, KLF11, FOS, NR3C1, KHDRBS3, PRDM1, PGR, IGF2, C1QBP, RUNX3, YBX1, HDAC2, SMAD3, RELA, FOXL2, HIF1A, FOXP1, HES5, ATP1B4, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, NFKB2, POU5F1, KAT2B, HDAC1, FOXP3, EZH2, SIRT1, ID2, STAT4, SMAD4, TWIST1, NR0B2, ZNF366, CDKN2A, TP63, EMX2, KLF10, GATA6, NAA15, SUV39H2, PAX2, USF2, DLX5, KLF9, IL16, PPRC1, TBPL2, NOTCH4, CHD5, NANOG, GATA5, TBX21, AHRR, OGG1, MAF, FHIT, TET1, CREB3L1, SRA1, MBD2, PIAS3 |
| regulation of transforming growth factor beta receptor signaling pathway | biological_process | ITGA3, FOLR1, ENG, ZEB1, TGFB1, SMAD7, SMAD3, SMAD2, SMAD4, IL17F |
| regulation of transforming growth factor beta2 production | biological_process | TGFB2, SMAD3, HIF1A, SMAD4 |
| regulation of translation | biological_process | AKT1, IGF1, EIF4EBP1, DAPK1 |
| regulation of translational initiation | biological_process | HSPB1, EIF3E |
| regulation of transmembrane transporter activity | biological_process | BCL2 |
| regulation of triglyceride biosynthetic process | biological_process | C3 |
| regulation of tumor necrosis factor production | biological_process | LTF, FOXP1, ANGPT1 |
| regulation of tumor necrosis factor-mediated signaling pathway | biological_process | TNFRSF1A, TNF |
| regulation of type B pancreatic cell development | biological_process | CLOCK |
| regulation of type B pancreatic cell proliferation | biological_process | ERRFI1 |
| regulation of type I interferon-mediated signaling pathway | biological_process | JAK1, TYK2 |
| regulation of tyrosine phosphorylation of Stat1 protein | biological_process | IL12B, IL23A |
| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | biological_process | CCNB1, PLK1 |
| regulation of uterine smooth muscle contraction | biological_process | TACR2, TACR1 |
| regulation of vascular endothelial growth factor production | biological_process | CCL2, CCR2, IL6 |
| regulation of vascular endothelial growth factor receptor signaling pathway | biological_process | VEGFC, FIGF |
| regulation of vascular endothelial growth factor signaling pathway | biological_process | PTP4A3 |
| regulation of vascular permeability | biological_process | SRC, TEK |
| regulation of vasculature development | biological_process | ID1 |
| regulation of vasculogenesis | biological_process | HEY1 |
| regulation of vasoconstriction | biological_process | ACE, AGTR1, EDN1 |
| regulation of vasodilation | biological_process | ACE, AGTR1, AGTR2 |
| regulation of ventricular cardiac muscle cell membrane depolarization | biological_process | GJA1, SMAD7 |
| regulation of ventricular cardiac muscle cell membrane repolarization | biological_process | GJA1 |
| regulation of vesicle-mediated transport | biological_process | NRP1 |
| regulation of viral genome replication | biological_process | BCL2 |
| regulation of Wnt signaling pathway | biological_process | ITGA3, HNF1B, DKK1 |
| regulation of wound healing | biological_process | PLAU |
| regulatory T cell differentiation | biological_process | TGFB1, FOXP3 |
| relaxation of vascular smooth muscle | biological_process | SOD1 |
| release of cytochrome c from mitochondria | biological_process | BCL2, CLU, JUN, BCL2L1, BAX |
| release of matrix enzymes from mitochondria | biological_process | BAX |
| release of sequestered calcium ion into cytosol | biological_process | FGF2, F2R, DRD2, CCL21, CCL19, TRPV1, CCR7 |
| release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | biological_process | CCL3, CCR5 |
| removal of superoxide radicals | biological_process | NOS3, SOD1, MPO, ATP7A |
| renal absorption | biological_process | AKR1C3 |
| renal artery morphogenesis | biological_process | NRP1 |
| renal filtration | biological_process | ITGA3 |
| renal inner medulla development | biological_process | CTNNB1 |
| renal outer medulla development | biological_process | CTNNB1 |
| renal sodium ion absorption | biological_process | SGK1 |
| renal system development | biological_process | GATA3, ITGA6, BMP4, CTNNB1, EMX2 |
| renal system process | biological_process | BCL2, BMP4, FAS |
| renal tubule morphogenesis | biological_process | COL4A1 |
| renal vesicle formation | biological_process | CTNNB1, WNT4 |
| renal vesicle induction | biological_process | WNT4 |
| renal water homeostasis | biological_process | AQP2 |
| renal water transport | biological_process | AQP2 |
| renin secretion into blood stream | biological_process | PCSK5 |
| renin-angiotensin regulation of aldosterone production | biological_process | AGTR1, AGTR2 |
| replication fork processing | biological_process | PCNA |
| replication fork protection | biological_process | BRCA2 |
| replicative cell aging | biological_process | CHEK2, TP63 |
| replicative senescence | biological_process | MME, CDKN1A, CDKN2A, CHEK2, TP53, TERT, ATM |
| reproductive process | biological_process | NR5A1 |
| reproductive structure development | biological_process | FGFR2, FKBP4 |
| resolution of meiotic recombination intermediates | biological_process | MLH1 |
| resolution of mitotic recombination intermediates | biological_process | XRCC3 |
| respiratory burst involved in defense response | biological_process | MPO |
| respiratory gaseous exchange | biological_process | CFTR, CSF2RB, EDNRA, EDN1, SFTPA1 |
| respiratory system development | biological_process | SPRY2 |
| respiratory tube development | biological_process | PCSK5 |
| response to acetate | biological_process | LIPC, CYP17A1 |
| response to acidic pH | biological_process | SRC, SERPINF1, SST |
| response to activity | biological_process | GSK3B, DNMT1, CCL5, IL10, LEP, CTNNB1, CCL2, PTN, BMP6, STAR, INSR, IGF1, ITGB1, ANGPT2, PLAU, CAT, EDN1, HIF1A, ADIPOQ, ESR2, AGER, DNMT3B |
| response to alkaloid | biological_process | BCHE, HIF1A |
| response to amine | biological_process | NME1, ITGA2, CTSB |
| response to amino acid | biological_process | MTHFR, PTGER4, CDKN1B, CASP3, GSTP1, LIPC, CCL2, MTOR, TIMP3, ICAM1, IL6, EDN1, RELA, SST, IL17A, PEMT |
| response to amphetamine | biological_process | DRD2, OXTR, SOD1, ICAM1, HDAC2, DPYSL2 |
| response to anesthetic | biological_process | HIF1A |
| response to angiotensin | biological_process | GSK3B |
| response to anoxia | biological_process | OXTR |
| response to antibiotic | biological_process | ID1, CASP3, JAK1, CCL2, STAR, HSP90AA1, SOD1, TP53, CYP1A1, IL6 |
| response to antidepressant | biological_process | DNMT1, DNMT3A |
| response to antipsychotic drug | biological_process | SOD1 |
| response to arsenic-containing substance | biological_process | GCLC, SERPINF1, CDKN1A, TNFRSF11B, CYP1A1, PTEN |
| response to ATP | biological_process | CASP1, IL1B, PTEN, P2RX3 |
| response to auditory stimulus | biological_process | TACR1, CXCL10, IL6, NTRK2, HIF1A, UCN |
| response to axon injury | biological_process | FOLR1, DRD2, LGALS1, SOD1, BAX, AIF1 |
| response to bacterium | biological_process | NOS2, CCL5, NFKB1, CASP1, CCL2, TLR4, SOCS3, IL6, RELA, DEFB1, IL27 |
| response to bisphenol A | biological_process | ESR2 |
| response to cadmium ion | biological_process | PCNA, CTNNB1, CDKN1B, SPARC, CAT |
| response to caffeine | biological_process | DNMT1, PPARG, IGF1, IL6, HDAC2, DNMT3B |
| response to calcium ion | biological_process | CCND1, PLA2G4A, ANXA5, SPARC, LIPC, SDC1, FGA, PTGES, PDCD6, THBS1, IL6 |
| response to cAMP | biological_process | NME1, BRAF, SPARC, SDC1, BSG, CYP17A1, JUN, FOS, RELA, TEK |
| response to carbohydrate | biological_process | LIPC, HNF1B, IL1B, P2RX3 |
| response to carbon monoxide | biological_process | IL10, SOD1 |
| response to cholesterol | biological_process | CCL5, CCL3, CCR5, TGFB1, SMAD2 |
| response to ciliary neurotrophic factor | biological_process | PTN |
| response to cobalamin | biological_process | RELA |
| response to cobalt ion | biological_process | CASP3, HIF1A |
| response to cocaine | biological_process | OPRM1, DRD2, MTOR, OXTR, CRH, HDAC2, DNMT3A, DPYSL2, BAX, DNMT3B |
| response to cold | biological_process | HSPD1, PPARG, ADM, HSP90AA1, MT-CO2, CXCL10, FOS, IL6, P2RX3 |
| response to copper ion | biological_process | NFKB1, LIPC, SOD1, IL1A, CP, ICAM1, BAX, S100A13, ATP7A |
| response to corticosteroid | biological_process | NOTCH1, ANXA1 |
| response to corticosterone | biological_process | CCND1, CDKN1A, PTGS1, STAR, FOS, CRH, BAX |
| response to cycloheximide | biological_process | FAS, FGA, BCL2L1 |
| response to cytokine | biological_process | BCL2, STAT3, CCL5, CTNNB1, IL6R, IL6ST, SPARC, FAS, LIFR, TIMP2, STAT6, OXTR, PTGS2, CYP17A1, JUN, TIMP1, PTGES, SOCS3, FOS, CTSB, IL4, IL6, RELA, BCL2L1, AIF1, MCL1, NFKB2, TIMP4, CXCL16 |
| response to DDT | biological_process | CCNB1 |
| response to dexamethasone | biological_process | IL1B, EDN1, ESR2 |
| response to dietary excess | biological_process | LEP, APOE |
| response to diuretic | biological_process | PPARG, IL1B |
| response to doxorubicin | biological_process | CHEK2 |
| response to drug | biological_process | GSK3B, BCL2, SRC, CDH1, GATA3, INHBA, CCND1, STAT3, DNMT1, ITGA3, PPARG, MMP13, CCL5, IGFBP2, APEX1, IL10, CTNNB1, CCNB1, MTHFR, PTGER4, SLC6A4, CDKN1B, NME1, DRD2, CASP3, CDKN1A, XRCC1, ITGA2, LGALS1, LIPC, FAS, CCL2, TIMP2, HNF1B, PTN, MDK, COMT, CDH3, OXTR, SRD5A2, PTGS2, VEGFC, COL18A1, MMP12, PTGER3, STAR, ITGB1, CYP17A1, JUN, IFNG, TGFB1, ANXA1, CYP2E1, SOD1, APOA1, BCHE, APOA2, MYC, PDGFA, CYP1A2, FYN, TNFRSF11B, SOCS3, FOS, THBS1, IL1B, PNP, ADA, IGF2, LTA, ICAM1, AMH, CAT, CYP1A1, IL4, IL6, EDN1, CRH, ABCB1, PTEN, TGFB2, HDAC2, RELA, DNMT3A, PARK7, HIF1A, DPYSL2, BAX, ADIPOQ, ESR2, ADAM17, DNMT3B, BLMH, EMX2, GATA6, ABCG2, PMS2, SST, DAD1, HSD11B2, CPB2, TIMP4, SEMA3C, OGG1, SRD5A1, PEMT |
| response to dsRNA | biological_process | TLR3 |
| response to electrical stimulus | biological_process | SRC, TACR2, TACR1, MSTN, IL6, S100A13, AIF1 |
| response to endoplasmic reticulum stress | biological_process | PIK3R1, ALOX15, CXCL8, BCL2L11, THBS1, AGR2, NFE2L2 |
| response to epidermal growth factor | biological_process | MAPK1, IL1R1 |
| response to epinephrine | biological_process | GSK3B |
| response to estradiol | biological_process | GSK3B, CCND1, STAT3, NR2F2, BMP4, DNMT1, WNT5A, IGFBP2, F3, LEP, CTNNB1, BRCA1, SLC6A4, AHR, CDKN1B, CASP3, BRCA2, GSTP1, TACR1, PTN, OXTR, PTGS2, PTGFR, PTGER3, AURKA, ESR1, INSR, CRYAB, TGFB1, ANXA1, FGA, PDGFA, C3, CD4, CYP1A2, WNT7A, SOCS3, IL1B, IGF2, GC, CAT, PTEN, DNMT3A, HIF1A, ESR2, EZH2, DNMT3B, UCN, IHH, POSTN, OGG1, SRD5A1 |
| response to estrogen | biological_process | GATA3, CCND1, PPARG, MMP13, CCL5, MAPK1, IGFBP2, CTNNB1, BRCA1, KRT19, CTNNA1, STS, HMOX1, FAS, MMP14, TIMP3, STAR, ESR1, CA2, HSP90AA1, APOA1, APOA2, C3, TNFRSF11B, WNT7A, MSTN, CRH, HIF1A, TEK, GHRL, ESR2, ZNF366, GATA6, SRD5A1 |
| response to ethanol | biological_process | GATA3, CCND1, STAT3, DNMT1, LEP, OPRM1, DRD2, SPARC, GSTP1, CCL2, VCAM1, TACR1, TNC, IL13, STAR, INSR, CYP2E1, SOD1, FYN, MSTN, CTSB, IL1B, IGF2, ICAM1, CAT, IL4, CRH, PTEN, DNMT3A, EIF4EBP1, ADIPOQ, ESR2, IL2, OGG1, PEMT |
| response to ether | biological_process | CRH |
| response to exogenous dsRNA | biological_process | MAPK1, TLR3 |
| response to external stimulus | biological_process | PON1, INHA |
| response to fatty acid | biological_process | SRC, CD36, LIPC, PTGS1, PON1, PTGS2, CAT |
| response to fibroblast growth factor | biological_process | TNC |
| response to fluid shear stress | biological_process | GJA1, F3, AKT1, NOS3 |
| response to fluoride | biological_process | FAS, PON1, FOXO1 |
| response to folic acid | biological_process | MTHFR, TIMP3, BCHE, ABCG2, OGG1 |
| response to follicle-stimulating hormone | biological_process | SRD5A2, SRD5A1 |
| response to food | biological_process | OPRM1, AKT1, SOCS3, GHRH, CYP1A1, MPO, HSD11B2 |
| response to fructose | biological_process | PTGS2, AGER |
| response to fungicide | biological_process | STAR, CYP17A1, HIF1A, SRD5A1 |
| response to gamma radiation | biological_process | BCL2, GATA3, BRCA2, CCL2, CHEK2, TP53, MYC, CXCL10, SOCS3, IL1B, GPX1, BAX, TP63, CCL7 |
| response to genistein | biological_process | FGA, ESR2, AGER |
| response to glucocorticoid | biological_process | BCL2, CCND1, BMP4, PLA2G4A, WNT5A, PTGDS, CCL5, HMGB1, IGFBP2, IL10, SHC1, CASP3, CDKN1A, SPARC, LIPC, FAS, CCL2, IL1RN, SDC1, MDK, BMP6, ADM, PTGS2, FN1, INSR, IGF1, ANXA1, BCHE, APOA2, TNF, C3, SOCS3, MSTN, IL1B, KRAS, IL6, HIF1A, ADIPOQ, AIF1, UCN, HSD11B2, IL22 |
| response to glucose | biological_process | EGR1, GJA1, CDKN1B, CASP3, HNF1B, TGFB1, APOA2, ANGPT2, THBS1, CTSB, PTEN, HIF1A, SMAD2, ADIPOQ, NR0B2, IRS2 |
| response to gold nanoparticle | biological_process | MPO |
| response to gonadotropin | biological_process | ITGA3, STAR, ITGB1, CYP17A1, ICAM1 |
| response to gravity | biological_process | SPARC, MSTN, FOS |
| response to growth factor | biological_process | OPRM1, FASLG, FAS, SOX2, MYC, GATA6 |
| response to growth hormone | biological_process | AKT1, IGFBP5, SRD5A1 |
| response to heat | biological_process | GCLC, DNMT1, PLA2G4A, AKT1, CCL2, TACR1, NOS3, CXCL12, IGF1, HSP90AA1, SOD1, SOCS3, MAP2K7, MSTN, TGFB1I1, IL1B, IL6, HSF1, MICA, P2RX3, SST, MICB, CPB2 |
| response to hepatocyte growth factor | biological_process | PLAU |
| response to herbicide | biological_process | STAR, CYP17A1, CYP1A1 |
| response to high density lipoprotein particle | biological_process | ADAM17 |
| response to histamine | biological_process | DRD2 |
| response to hormone | biological_process | GCLC, PLA2G4A, AKT1, CTNNB1, LIPC, TIMP2, MMP14, TACR1, MDK, TIMP3, INSR, ANG, ANXA1, TIMP1, SOCS3, GHRL, ESR2, SFRP4, TIMP4, RERG, PIAS3 |
| response to human chorionic gonadotropin | biological_process | ESR2 |
| response to hydrogen peroxide | biological_process | BCL2, SRC, PLA2G4A, SHC1, CASP3, HMOX1, SDC1, STAR, JUN, CRYAB, SOD1, GPX1, HP, ADA, CAT, RELA, PARK7, SIRT1 |
| response to hydroperoxide | biological_process | GPX1 |
| response to hydrostatic pressure | biological_process | COL18A1 |
| response to hyperoxia | biological_process | WNT5A, CDKN1A, PLAU, CAT, CYP1A1, HDAC2, AGER |
| response to hypoxia | biological_process | VEGFA, NOS2, MMP13, LEP, SHC1, MTHFR, SLC6A4, CASP1, CDKN1B, DRD2, CASP3, XRCC1, ENG, EDNRA, ITGA2, FLT1, HMOX1, USF1, LIPC, FAS, CCL2, VCAM1, MMP14, ARNT, HMOX2, ADM, CXCL12, IGF1, ANG, CRYAB, TGFB1, ACTN4, PLAT, PRKCB, PDGFA, SOCS3, ANGPT2, CLDN3, THBS1, FIGF, IL1B, PLAU, ADA, LTA, ICAM1, CAT, CYP1A1, EDN1, MMP2, TGFB2, SMAD3, HIF1A, CXCR4, TEK, PAK1, ADIPOQ, PPARA, ATM, SMAD4, ADAM17, DNMT3B, CX3CL1, P2RX3, HSD11B2, POSTN |
| response to immobilization stress | biological_process | PPARG, CYP1A2, FOS, CYP1A1, CRH, UCN2 |
| response to inactivity | biological_process | IL10, DRD2, CAT |
| response to inorganic substance | biological_process | LIPC, FAS, PDGFA, TNFRSF11B, PTEN, RELA |
| response to insecticide | biological_process | STAR, CYP17A1, ESR2 |
| response to insulin | biological_process | GSK3B, EGR1, CCL5, IL10, LEP, SHC1, MTOR, ADM, INSR, SOCS3, CAT, IL6, RELA, FOXO1, PPARA, SIRT1, HSD11B2, RETN |
| response to insulin-like growth factor stimulus | biological_process | GSK3B, AKT1 |
| response to interferon-gamma | biological_process | CXCL16 |
| response to interleukin-1 | biological_process | SRC, CHI3L1, MTHFR, PTGER4, IL1R1, SELE, ANXA1, LGALS9, FIGF, RELA |
| response to interleukin-13 | biological_process | CCL11 |
| response to interleukin-4 | biological_process | CTSB, CCL11 |
| response to interleukin-6 | biological_process | CHI3L1 |
| response to ionizing radiation | biological_process | H2AFX, DNMT1, BRCA1, VCAM1, CCR2, STAR, XRCC3, CYP17A1, ICAM1, DNMT3A, BAX, ATM, DNMT3B |
| response to iron ion | biological_process | BCL2, CCND1, DRD2, BMP6, ABCG2, HAMP |
| response to iron(III) ion | biological_process | CYP1A1, ATP7A |
| response to ischemia | biological_process | BCL2, UCHL1, FN1, EIF4EBP1 |
| response to kainic acid | biological_process | PTN |
| response to L-ascorbic acid | biological_process | ITGA2, SPARC, GSTP1, IL1B, CAT |
| response to L-glutamate | biological_process | GSK3B |
| response to laminar fluid shear stress | biological_process | TGFB1, SMAD7 |
| response to lead ion | biological_process | DNMT1, SPARC, STAR, CAT, DNMT3A |
| response to leptin | biological_process | CCND1, STAT3, LEPR, STAR, EDN1, SIRT1 |
| response to light intensity | biological_process | CAT |
| response to light stimulus | biological_process | CLU, DRD2, CLOCK, FOS, NTRK2, OGG1 |
| response to linoleic acid | biological_process | CD36, ADIPOQ |
| response to lipid | biological_process | PCNA, PPARG, CD36, BRCA1, GATA2, LIPC |
| response to lipid hydroperoxide | biological_process | GPX3 |
| response to lipopolysaccharide | biological_process | NOS2, DNMT1, PLA2G4A, F2R, TNFRSF1A, CCL5, MAPK1, F3, IL10, OPRM1, PTGER4, CASP1, NOTCH1, CASP3, FASLG, TNFRSF1B, CD40, EDNRA, SPARC, CXCL1, FAS, CCL2, IDO1, VCAM1, SELP, SELE, CXCL2, COMT, IL12A, IL13, ADM, PTGS2, CCR2, CXCL5, PTGFR, PTGER2, IGF1, JUN, CXCL10, LGALS9, PTGES, TLR4, CYP1A2, TNFRSF11B, SOCS3, FOS, SLPI, CXCL13, TNFRSF21, IL1B, LTA, ICAM1, CYP1A1, MPO, IL6, EDN1, CTSG, HDAC2, RELA, FOXP1, HSF1, NFKB2, PTPN22, ADAM17, CXCL6, LOXL1, TIMP4, DCN, CCR7 |
| response to lithium ion | biological_process | GSK3B, PLA2G4A, IGFBP2, PTGS2 |
| response to low-density lipoprotein particle | biological_process | PPARG, F3 |
| response to magnesium ion | biological_process | CCND1, LIPC, BMP6, C3, TNFRSF11B, THBS1 |
| response to manganese ion | biological_process | PTGS2, INSR |
| response to mechanical stimulus | biological_process | SRC, BMP4, PPARG, MMP13, IGFBP2, CHI3L1, F3, CCNB1, PTGER4, CCL2, MMP14, TNC, IL13, TIMP3, CXCL12, IGF1, JUN, FOS, ANGPT2, CTSB, MPO, IL6, RELA, HIF1A, P2RX3, POSTN, RETN, DCN |
| response to mercury ion | biological_process | GSTP1, BSG |
| response to metal ion | biological_process | CASP3 |
| response to metformin | biological_process | PPARG |
| response to methylglyoxal | biological_process | AGER |
| response to methylmercury | biological_process | PLA2G4A, CYP17A1 |
| response to mineralocorticoid | biological_process | SRC, KRAS |
| response to misfolded protein | biological_process | CLU |
| response to molecule of bacterial origin | biological_process | IL10, CXCL8, CXCL2, TLR2, TLR9 |
| response to morphine | biological_process | OPRM1, DRD2, EDNRA, TACR1, MTOR, FGA, IL1B, ADA, RELA |
| response to muramyl dipeptide | biological_process | NOTCH1, RELA, NOD2, JAG1 |
| response to muscle activity | biological_process | ITGA2, MSTN, HIF1A, POSTN, SRD5A1 |
| response to muscle stretch | biological_process | NFKB1, JUN, FOS, EDN1, RELA |
| response to nematode | biological_process | CYP1A1 |
| response to nerve growth factor | biological_process | PTN |
| response to nicotine | biological_process | BCL2, SHC1, DRD2, CASP3, HMOX1, VCAM1, TACR1, IL13, STAR, IGF1, IGF2, EDN1, HDAC2 |
| response to nitric oxide | biological_process | BMP4, IL1R1, CCL19, CCR7 |
| response to nitrosative stress | biological_process | GCLC |
| response to nutrient | biological_process | PPARG, IGFBP2, LEP, BRCA1, SLC6A4, BRCA2, VCAM1, MTOR, SSTR1, AKR1C3, STAR, IGF1, APOA1, BCHE, TNFRSF11B, IL1B, CP, LTA, IL4, PTEN, ADIPOQ, SST, DAD1, ADIPOR2, PEMT |
| response to nutrient levels | biological_process | SRC, DNMT1, CCL5, LEP, GSTP1, MMP7, LIPC, IL15, PON1, SRD5A2, STAR, INSR, IGF1, ITGB1, CYP17A1, SOD1, IGF2, GC, IL6, DNMT3A, ADIPOQ, ESR2, PAX2 |
| response to organic cyclic compound | biological_process | CCND1, STAT3, BMP4, WNT5A, PPARG, CCL5, SHC1, CTNNB1, PTGER4, NFKB1, AHR, CDKN1B, ID1, CASP3, CDKN1A, CTNNA1, EDNRA, ITGA2, STS, LIPC, LIFR, MMP14, SELP, TACR1, HNF1B, COMT, OXTR, SRD5A2, PTGS2, TIMP3, MMP12, STAR, MKI67, IGF1, CYP17A1, JUN, TGFB1, ANXA1, PTGES, CYP1A2, SOCS3, FOS, ANGPT2, CTSB, IL1B, IGF2, ICAM1, AMH, CYP1A1, IL4, IL6, EPHX1, PTEN, RELA, ESR2, SRD5A1, STC1, CD83, TET2 |
| response to organic substance | biological_process | AKR1B1, CDH1, CCND1, STAT3, DNMT1, PLA2G4A, WNT5A, PPARG, IL10, IL12B, ANXA5, AKT1, BRCA1, SLC6A4, CASP3, SPP1, CDKN1A, XRCC1, S100P, SDC1, SRD5A2, ADM, PTGS2, TIMP3, STAR, XRCC3, IGF1, CA2, CYP17A1, JUN, TGFB1, SOD1, TIMP1, TNF, PDGFA, CYP1A2, CYP1A1, PTEN, RELA, TEK, PAK1, P2RX3, TIMP4 |
| response to organonitrogen compound | biological_process | CCND1, PLA2G4A, APEX1, CDKN1A, AGTR2, PTGS1, FLT3, PTGS2, CYP2E1, IL1B, SST |
| response to organophosphorus | biological_process | AKR1C1 |
| response to osmotic stress | biological_process | ATF2, MAP2K7 |
| response to oxidative stress | biological_process | GCLC, BCL2, GPX3, AKT1, NFKB1, MBL2, HMOX1, MMP14, LPO, PTGS1, PTGS2, SOD1, APOE, GPX1, KRT1, CAT, MPO, PARK7, SIRT1, UCN, MICB, OGG1 |
| response to ozone | biological_process | TACR1, FN1, CYP2E1, IL1B, CAT, EDN1 |
| response to pain | biological_process | TACR1, COMT, SLC6A2, CRH, UCN |
| response to parathyroid hormone | biological_process | ITGA2 |
| response to peptide | biological_process | OXTR |
| response to peptide hormone | biological_process | STAT3, GJA1, CDKN1B, BRAF, SPARC, STS, LIPC, FAS, OXTR, SRD5A2, BSG, STAR, CXCL12, ANXA1, TIMP1, SOCS3, CTSB, IL1B, TEK, TIMP4 |
| response to peptidoglycan | biological_process | IL6 |
| response to pH | biological_process | GJA1, STS, CA2 |
| response to phenylpropanoid | biological_process | CAT |
| response to potassium ion | biological_process | CLU |
| response to progesterone | biological_process | PTGER4, CCL2, TACR1, PTN, OXTR, PTGER3, PTGER2, TGFB1, C3, CLDN4, SOCS3, FOS, THBS1, TGFB2, RELA |
| response to prostaglandin E | biological_process | PTGER4, CCL21, CCL19, CCR7 |
| response to prostaglandin F | biological_process | EDN1 |
| response to purine-containing compound | biological_process | HIF1A |
| response to radiation | biological_process | BCL2, TXN, KIT, OPRM1, IL1R1, PTGS2, CXCL12, JUN, TGFB1, ANGPT2, IGF2, CAT, BCL2L1, OGG1, CCL11 |
| response to reactive oxygen species | biological_process | TXN, PRDX6, GPX3, GSTP1, ALDH3A2, SOD1, APOE, GPX1, CAT |
| response to redox state | biological_process | CLOCK |
| response to retinoic acid | biological_process | BMP4, PPARG, IGF2R, IGFBP2, BMP6, HSD17B2, CYP17A1, PDGFA, PTGES, DKK1, MICB |
| response to salt | biological_process | PTGER4, PTGER3, EDN1, ESR2 |
| response to salt stress | biological_process | CCL5, HSP90AA1, TNF, HIF1A, BAX |
| response to selenite ion | biological_process | AGER |
| response to selenium ion | biological_process | GPX1 |
| response to starvation | biological_process | PPARG, SSTR1, ADM |
| response to statin | biological_process | IL1B |
| response to steroid hormone | biological_process | BCL2, CCND1, IGFBP2, SPP1, OXTR, SRD5A2, STAR, IGF1, CA2, CYP17A1, GC, SST, HSD11B2 |
| response to stilbenoid | biological_process | CD36, IL1B |
| response to stimulus | biological_process | CDH3, TIMP3, DLL4 |
| response to stress | biological_process | AKR1B1, MAPK1, STIP1, MTOR, HSP90AA1, EGFR, SGK1, C5, ERRFI1, UCN2 |
| response to sucrose | biological_process | ADIPOQ |
| response to sulfur dioxide | biological_process | ICAM1 |
| response to superoxide | biological_process | SOD1 |
| response to symbiotic bacterium | biological_process | GPX1 |
| response to temperature stimulus | biological_process | F3, P2RX3 |
| response to testosterone | biological_process | BMP4, DNMT1, WNT5A, NME1, SRD5A2, INSR, MSTN, EDN1, ESR2, DEFB1, SRD5A1 |
| response to thyroid hormone | biological_process | AKR1B1, ANXA5, ANXA2 |
| response to toxic substance | biological_process | BCL2, CDH1, DNMT1, CCL5, MAPK1, SHC1, CCNB1, CCL3, SLC6A4, AHR, DRD2, CDKN1A, GSTP1, FAS, SDC1, PON1, STAR, CYP17A1, FOS, GPX1, CAT, CYP1A1, EPHX1, DNMT3A, BAX, DNMT3B, BLMH, CYP1B1 |
| response to transforming growth factor beta | biological_process | IL1R1, ITGB1, EDN1, RUNX3, SMAD4 |
| response to tumor necrosis factor | biological_process | CCL5, CHI3L1, CASP3, SELE, PTGS2, INSR, MAP2K7, ADIPOQ, CXCL16 |
| response to ultrasound | biological_process | GSK3B |
| response to unfolded protein | biological_process | HSPD1, HSPA6, HSPA4, HSP90AA1, HSPB1, THBS1, CREB3L1 |
| response to UV | biological_process | MSH6, CASP3, CDKN1A, USF1, MAP2K7, CAT |
| response to UV-A | biological_process | CCND1, AKT1, EGFR |
| response to UV-B | biological_process | MSH2, BCL2, IL12B, IL12A, RELA |
| response to UV-C | biological_process | BRCA2 |
| response to virus | biological_process | SRC, GATA3, HMGA2, CCL5, CLU, CFL1, HMGA1, STMN1, IL12A, CXCL12, IFNG, TNF, CXCL10, HSPB1, ENO1, CCL22, TLR3, CYP1A1, BCL2L1, CXCR4, CCL19, FOXP3, MST1R, PIM2, ISG20, TBX21, CCL11, LILRB1 |
| response to vitamin | biological_process | PEMT |
| response to vitamin A | biological_process | DNMT1, PPARG, CAT, CYP1A1, DNMT3A, AGER, DNMT3B |
| response to vitamin B2 | biological_process | MTHFR |
| response to vitamin B3 | biological_process | CCL2 |
| response to vitamin D | biological_process | PLA2G4A, SPP1, PTGS2, INSR, TGFB1, CXCL10, CD4, IL1B, STC1, CYP24A1 |
| response to vitamin E | biological_process | CCND1, LEP, ADA, CAT |
| response to water deprivation | biological_process | AKR1B1, ATF2, ESR2 |
| response to water-immersion restraint stress | biological_process | PTGER4 |
| response to wounding | biological_process | F2R, CLU, F3, CASP3, CCR1, CCL2, MDK, TNC, SOX2, ADM, CCR2, FN1, TGFB1, PDGFA, NRP1, CTSB, GPX1, WNT1, CYP1A1, IL6, RAC1, TGFB2, BAX, POU5F1, AGER |
| response to X-ray | biological_process | MSH2, CCND1, CASP3, CDKN1A, BRCA2, ANXA1, TP53, XRCC4, HIF1A, TP63 |
| response to xenobiotic stimulus | biological_process | GCLC, AHR, GPX1, AHRR |
| response to yeast | biological_process | PTX3, ADM, ANG, MPO, IL6, NPY |
| response to zinc ion | biological_process | VCAM1, CA2, PTEN, ATP7A |
| retina development in camera-type eye | biological_process | BMP4, SERPINF1, LIF, PTN, BMPR1B, IL4, NTRK2, BAX, NECTIN1 |
| retina homeostasis | biological_process | AZGP1, CDH3, SOD1, LTF, HSPB1, KRT1, TF, ACTB |
| retina layer formation | biological_process | PROM1 |
| retina morphogenesis in camera-type eye | biological_process | PROM1, NECTIN3 |
| retina vasculature development in camera-type eye | biological_process | PDGFRA, HIF1A, CYP1B1 |
| retina vasculature morphogenesis in camera-type eye | biological_process | NRP1 |
| retinal blood vessel morphogenesis | biological_process | COL4A1, CYP1B1 |
| retinal cell programmed cell death | biological_process | FASLG, BAX |
| retinal ganglion cell axon guidance | biological_process | BMPR1B, NRP1 |
| retinal metabolic process | biological_process | AKR1C3, AKR1C1, CYP1B1 |
| retinal pigment epithelium development | biological_process | PAX2 |
| retinal rod cell development | biological_process | NTRK2, NAGLU |
| retinal rod cell differentiation | biological_process | PTN |
| retinoic acid biosynthetic process | biological_process | RBP1 |
| retinoic acid catabolic process | biological_process | CYP26A1 |
| retinoic acid receptor signaling pathway | biological_process | ACTN4 |
| retinoid metabolic process | biological_process | SDC4, RBP1, SDC1, AKR1C3, APOA1, APOA2, APOE, RARRES2, AKR1C1 |
| retinol metabolic process | biological_process | AKR1C3, CYP1B1 |
| retrograde axonal transport | biological_process | SOD1 |
| retrograde transport, endosome to Golgi | biological_process | STX5 |
| retrograde vesicle-mediated transport, Golgi to ER | biological_process | KIFAP3 |
| reverse cholesterol transport | biological_process | CETP, CLU, LIPC, APOA1, APOA2, APOE, SCARB1 |
| Rho protein signal transduction | biological_process | BCL6, CFL1, AGTR1, EDNRA, LIMK1, RHOA |
| rhombomere 3 development | biological_process | HOXB2 |
| rhombomere 4 development | biological_process | HOXB2 |
| rhythmic excitation | biological_process | EDN1 |
| rhythmic process | biological_process | GSK3B, PPARG, AHR, ID1, CLOCK, TP53, SUV39H1, HDAC2, PPARA, NFKB2, KAT2B, HDAC1, EZH2, SIRT1, ID2, TWIST1, KLF10, SUV39H2, KLF9 |
| rhythmic synaptic transmission | biological_process | PTEN |
| ribosome biogenesis | biological_process | C1QBP |
| RNA biosynthetic process | biological_process | TERT |
| RNA catabolic process | biological_process | ISG20 |
| RNA destabilization | biological_process | TNFRSF1B |
| RNA phosphodiester bond hydrolysis | biological_process | AZGP1, ANG |
| RNA phosphodiester bond hydrolysis, endonucleolytic | biological_process | APEX1, DICER1 |
| RNA phosphodiester bond hydrolysis, exonucleolytic | biological_process | ISG20 |
| RNA processing | biological_process | DICER1 |
| RNA splicing | biological_process | LGALS3, WT1, C1QBP, YBX1 |
| RNA-dependent DNA biosynthetic process | biological_process | TERT |
| rod bipolar cell differentiation | biological_process | PTN |
| Roundabout signaling pathway | biological_process | RHOA |
| rRNA processing | biological_process | SUV39H1, SIRT1, CDKN2A, RPL41, ISG20 |
| rRNA transcription | biological_process | ANG |
| ruffle assembly | biological_process | RAC1, AIF1 |
| ruffle organization | biological_process | MTOR, CCL21, CSF1R, RAC1, CCR7 |
| S-adenosylhomocysteine metabolic process | biological_process | DNMT1, DNMT3A, DNMT3B, PEMT |
| S-adenosylmethioninamine metabolic process | biological_process | DNMT1, DNMT3A, DNMT3B |
| S-adenosylmethionine biosynthetic process | biological_process | MAT2A |
| S-adenosylmethionine metabolic process | biological_process | DNMT1, MTHFR, PEMT |
| S-shaped body morphogenesis | biological_process | HES5 |
| saliva secretion | biological_process | AQP5 |
| salivary gland morphogenesis | biological_process | FGFR1, EGFR, TGFB1, TGFB2 |
| sarcomere organization | biological_process | KRT19, ITGB1 |
| Schwann cell differentiation | biological_process | ERBB3, ADAM22 |
| Schwann cell proliferation | biological_process | CTNNB1 |
| sebaceous gland development | biological_process | SMAD4 |
| sebum secreting cell proliferation | biological_process | PRDM1 |
| secondary heart field specification | biological_process | BMP4 |
| secondary metabolite biosynthetic process | biological_process | CYP11A1 |
| secretion | biological_process | CA2, PTGES2 |
| secretion by cell | biological_process | AXL, TYRO3 |
| secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development | biological_process | NOTCH1 |
| semaphorin-plexin signaling pathway | biological_process | MET, NRP1, RAC1, SEMA3A, SEMA3C |
| semaphorin-plexin signaling pathway involved in axon guidance | biological_process | NRP1, SEMA3A |
| semaphorin-plexin signaling pathway involved in neuron projection guidance | biological_process | NRP1, NRP2, SEMA3A |
| semicircular canal development | biological_process | GATA2 |
| semicircular canal morphogenesis | biological_process | ZEB1 |
| seminiferous tubule development | biological_process | SMAD4 |
| senescence-associated heterochromatin focus assembly | biological_process | HMGA2, HMGA1, CDKN2A |
| sensory neuron axon guidance | biological_process | NRP1 |
| sensory organ boundary specification | biological_process | NTF4 |
| sensory perception | biological_process | OPRM1 |
| sensory perception of mechanical stimulus | biological_process | IFNG |
| sensory perception of pain | biological_process | MME, MAPK1, IL12B, OPRM1, UCHL1, EDNRA, TACR1, PTGS1, PTGS2, EDN1, CRHR2 |
| sensory perception of smell | biological_process | DRD2 |
| sensory perception of sound | biological_process | FGFR1, CDKN1B, CASP3, SOD1, SPRY2, GPX1, ICAM1, UCN |
| sensory perception of taste | biological_process | CD36, P2RX3 |
| sensory system development | biological_process | SEMA3A |
| sequestering of triglyceride | biological_process | TNF, IL1B |
| serine phosphorylation of STAT3 protein | biological_process | IL24 |
| serotonin metabolic process | biological_process | MAOA, ATP7A, SRD5A1 |
| serotonin secretion by platelet | biological_process | FCER1G |
| serotonin transport | biological_process | SLC6A4 |
| serotonin uptake | biological_process | SLC6A4 |
| Sertoli cell development | biological_process | SDC1, ESR1, ESR2 |
| Sertoli cell proliferation | biological_process | ESR1, FSHB, BAX, ESR2 |
| sesquiterpenoid metabolic process | biological_process | ALDH3A2 |
| sex determination | biological_process | WT1, AMH, SRD5A1 |
| sex differentiation | biological_process | AR, SRD5A2, CYP17A1, WNT7A, AMH, BAX, AMHR2, WNT4, SRD5A1 |
| sexual reproduction | biological_process | STAT3, IL12B, LEP, LEPR |
| short-term memory | biological_process | SERPINF1, MDK, COMT |
| signal complex assembly | biological_process | SRC, PTK2 |
| signal peptide processing | biological_process | GAS6, PCSK5 |
| signal transduction | biological_process | SRC, TXN, GATA3, FGF2, FSHR, MET, STAT3, NR2F2, CRHR1, F2R, PPARG, TNFRSF1A, MAPK1, IGF2R, IGFBP2, GJA1, PIK3R1, KIT, LEP, CXCL8, OPRM1, ANXA5, AKT1, SHC1, PTGER4, NFKB1, CASP1, AR, TNFSF10, ERBB3, DRD2, FPR1, PLCD1, RASSF2, FASLG, SDC4, CCR1, CCR5, CXCR3, CSF2RB, VDR, BRAF, AXL, AGTR1, AGTR2, ANXA4, FST, IGFBP5, IL6ST, EDNRA, CRHBP, SPARC, LGALS1, IGFBP1, CNTF, CXCL1, IL1R1, CXCR1, CXCR2, KITLG, PECAM1, FAS, CCL2, IL2RB, IL15, STMN1, STAT6, TACR2, TACR1, MDK, IGFBP4, LHCGR, MRC1, MTOR, FCER1G, OXTR, SSTR1, IL13, ADM, SSTR5, VEGFC, CCR2, CXCL5, PTGFR, PTGER3, PTGER2, KIR3DL1, CXCL12, CCR9, ESR1, IGF1, GREM1, HSP90AA1, EGFR, FGF1, CLOCK, ANXA1, MAP3K7, LGR5, FGA, IGF1R, PRKCB, INHA, S100A6, CXCL10, C3, PTGES, TLR2, TLR4, ERBB2, CD4, TNFRSF11B, CXCR6, CCL22, CLDN4, SOCS3, MAP2K7, NRP1, ANGPT2, TLR3, CAPN5, NR3C1, CLDN3, KALRN, TNFRSF21, NCR1, PGR, IL1B, DIRAS3, CXCL14, PAK4, EGF, PLAU, NRAS, KRAS, CGA, FSHB, LHB, LTA, CD74, RLN1, CRH, CSF1R, HIF1A, GAS6, TYRO3, DPYSL2, PLAUR, PLCB1, CXCR4, TEK, F2RL1, TLR9, ESR |
| signal transduction by p53 class mediator | biological_process | CDKN1A, GREM1 |
| signal transduction by protein phosphorylation | biological_process | KDR, INSR, BMPR1B, PAK4, TGFB2, TYRO3, PAK1, AMHR2 |
| signal transduction in response to DNA damage | biological_process | CHEK2, WNT1 |
| signal transduction involved in intra-S DNA damage checkpoint | biological_process | CHEK2 |
| signal transduction involved in mitotic G2 DNA damage checkpoint | biological_process | ATM |
| signal transduction involved in regulation of gene expression | biological_process | EPCAM, SMAD3, SMAD2 |
| signaling | biological_process | CCL3, CCR5 |
| single fertilization | biological_process | HOXA10, HOXA11, FOXL2, PARK7, MST1R, SMAD4, IGSF8, OVGP1 |
| single organismal cell-cell adhesion | biological_process | BCL2, SRC, CDH1, SHC1, CTNNB1, CD44, VCAM1, SELP, CDH3, EGFR, CYR61, ITGB2, ICAM1, CDC42, NECTIN1, NECTIN3, ADAM8, VEZT |
| single strand break repair | biological_process | XRCC1, SIRT1 |
| single-organism behavior | biological_process | ITGA3 |
| siRNA loading onto RISC involved in RNA interference | biological_process | DICER1 |
| sister chromatid biorientation | biological_process | RB1 |
| sister chromatid cohesion | biological_process | BIRC5, PLK1 |
| sister chromatid segregation | biological_process | LATS1 |
| skeletal muscle atrophy | biological_process | IL15, MSTN |
| skeletal muscle cell differentiation | biological_process | EGR1, NOTCH1, RB1, FOS |
| skeletal muscle contraction | biological_process | HSP90AA1 |
| skeletal muscle fiber development | biological_process | GPX1 |
| skeletal muscle satellite cell activation | biological_process | WNT7A |
| skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration | biological_process | IGF1, WNT7A, EZH2 |
| skeletal muscle satellite cell migration | biological_process | RHOC, RHOA |
| skeletal muscle tissue development | biological_process | NR2F2, CTSB, CSF1R, IGSF8, DCN |
| skeletal muscle tissue growth | biological_process | IGFBP5, CRHR2 |
| skeletal muscle tissue regeneration | biological_process | GJA1, SOX15, MSTN, GPX1, PLAU |
| skeletal system development | biological_process | FGFR1, BMP4, MMP9, CTNNB1, RASSF2, VDR, VCAN, HOXA10, BMP6, IGFBP4, HOXA11, PRELP, IGF1, INHA, AHSG, BMPR1B, TNFRSF11B, IGF2, EDN1, COL5A2, TGFB2, SMAD3, TP63, KLF10, DLX5, IHH, POSTN |
| skeletal system morphogenesis | biological_process | FGFR1, FGFR2, HOXB2, MMP2 |
| skin development | biological_process | ITGA6, ITGA3, CTNNB1, STS, PDGFA, COL5A2, ATP7A |
| skin morphogenesis | biological_process | ITGA2, ERRFI1, TP63 |
| sleep | biological_process | OXTR, FOS, IL18 |
| SMAD protein complex assembly | biological_process | TGFB1, SMAD3, SMAD2, SMAD4 |
| SMAD protein import into nucleus | biological_process | TOB1, JUN, TGFB1, TGFB2 |
| SMAD protein signal transduction | biological_process | INHBA, BMP4, VIM, BMP6, JUN, TGFB1, INHA, MSTN, FOS, GDF9, TGFB2, SMAD3, SMAD2, SMAD4, NODAL, GDF15 |
| small GTPase mediated signal transduction | biological_process | HMOX1, RHOC, DIRAS3, NRAS, KRAS, CDC42, RAC1, RND3, RHOA, RERG |
| smooth muscle adaptation | biological_process | IL1B |
| smooth muscle cell differentiation | biological_process | BMP4, CTNNB1, GATA6, WNT4 |
| smooth muscle cell migration | biological_process | ITGB3, PLAT, PLAU |
| smooth muscle cell proliferation | biological_process | EDNRA |
| smooth muscle contraction | biological_process | EDNRA |
| smooth muscle contraction involved in micturition | biological_process | TACR1 |
| smooth muscle hyperplasia | biological_process | HMOX1, NOS3 |
| smooth muscle tissue development | biological_process | BMP4, ENG, TP63 |
| smoothened signaling pathway | biological_process | BMP4, HES5, IHH |
| social behavior | biological_process | SLC6A4, MTOR, OXTR, IL1B, KRAS, PTEN, UCN |
| sodium ion transport | biological_process | SGK1 |
| sodium-independent organic anion transport | biological_process | SLCO2A1, SLCO4A1 |
| somatic hypermutation of immunoglobulin genes | biological_process | MSH2, MSH6, MLH1, PMS2 |
| somatic recombination of immunoglobulin gene segments | biological_process | MSH2, MSH6, MLH1 |
| somatic recombination of immunoglobulin genes involved in immune response | biological_process | MSH2, MLH1 |
| somatic stem cell division | biological_process | KIT, NOTCH1, WNT7A, TGFB2, CDKN2A |
| somatic stem cell population maintenance | biological_process | YAP1, FGF2, STAT3, KIT, BRAF, GATA2, TDGF1, SOX2, WNT7A, SMAD2, POU5F1, SMAD4, KLF10, NANOG |
| somatostatin signaling pathway | biological_process | SSTR1, SSTR5 |
| somatotropin secreting cell differentiation | biological_process | WNT4 |
| somite development | biological_process | WNT5A, IHH |
| somite rostral/caudal axis specification | biological_process | SMAD4 |
| somitogenesis | biological_process | WNT5A, SMAD3, ATM, SEMA3C |
| sorbitol biosynthetic process | biological_process | AKR1B1 |
| specification of animal organ position | biological_process | BMP4 |
| specification of loop of Henle identity | biological_process | HES5 |
| specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway | biological_process | BMP4 |
| Spemann organizer formation | biological_process | WNT1 |
| sperm capacitation | biological_process | CFTR, SLC26A8 |
| sperm ejaculation | biological_process | SLC6A4, TACR1, OXTR |
| spermatid development | biological_process | KIT, PRM1, NECTIN3 |
| spermatid differentiation | biological_process | BAX |
| spermatogenesis | biological_process | H2AFX, MLH1, FSHR, BCL6, IGF2R, KIT, CCNB1, NOTCH1, ACE, AXL, BRCA2, FAS, HOXA10, SSTR1, HOXA11, CLOCK, SOD1, FSTL3, BCL2L11, CTSB, KHDRBS3, PLAU, PRM1, BCL2L1, DNMT3A, TYRO3, BAX, HSF1, SIRT1, SMAD4, CADM1, TP63, SLC26A8, PAFAH1B2, DNMT3L, WFDC2, CHD5 |
| spermatogenesis, exchange of chromosomal proteins | biological_process | CHD5 |
| sphingolipid biosynthetic process | biological_process | ALDH3A2, SGPP2 |
| sphingolipid metabolic process | biological_process | PSAP, SMPD3 |
| sphingomyelin catabolic process | biological_process | SMPD3 |
| sphingomyelin metabolic process | biological_process | SMPD3 |
| sphingosine metabolic process | biological_process | SGPP2 |
| spinal cord association neuron differentiation | biological_process | WNT1 |
| spinal cord development | biological_process | AKT1, PTN, MTOR, DPYSL2, SRD5A1 |
| spindle assembly involved in female meiosis I | biological_process | AURKA |
| spindle checkpoint | biological_process | BIRC5 |
| spindle organization | biological_process | AURKA |
| spleen development | biological_process | BCL2, FAS, BCL2L11, NFKB2, ADAM17, TET2 |
| spongiotrophoblast differentiation | biological_process | LIF, SOCS3 |
| spongiotrophoblast layer development | biological_process | ADM |
| sprouting angiogenesis | biological_process | NOTCH1, FLT4, NRP1, THBS1, CDC42, TEK, ANGPT1 |
| squamous basal epithelial stem cell differentiation involved in prostate gland acinus development | biological_process | FGFR2, TP63 |
| SRP-dependent cotranslational protein targeting to membrane | biological_process | RPL41 |
| startle response | biological_process | DRD2, NRG1, UCN |
| STAT protein import into nucleus | biological_process | F2R, EGF |
| stem cell development | biological_process | WNT7A |
| stem cell differentiation | biological_process | HMGA2, KIT, EPCAM, LIF, A2M, PAX2 |
| stem cell population maintenance | biological_process | FGFR1, STAT3, KIT, CTNNB1, LIF, NODAL, NANOG, TET1 |
| stem cell proliferation | biological_process | ABCB1 |
| steroid biosynthetic process | biological_process | CYP19A1, PRLR, HSD3B2, HSD17B1, SRD5A2, HSD17B3, HSD17B2, STAR, CYP17A1, CYP11A1, HSD17B7, SRD5A1 |
| steroid catabolic process | biological_process | STS, SRD5A2, CYP1A2 |
| steroid hormone mediated signaling pathway | biological_process | NR2F2, BMP4, PPARG, AR, VDR, ESR1, NR5A2, PGRMC2, NR3C1, PGR, NR5A1, ESR2, PPARA, GPER1, NR0B2 |
| steroid hormone receptor complex assembly | biological_process | FKBP4 |
| steroid metabolic process | biological_process | AKR1D1, CETP, CYP2A6, STS, CYP2B6, SRD5A2, CYP2C19, AKR1C3, AKR1C2, CYP17A1, CYP2E1, CYP11A1, APOA1, APOE, CYP1A2, CRH, CYP1B1, SRD5A1, SULT1E1 |
| sterol metabolic process | biological_process | CYP19A1, CYP17A1, CYP11A1, CYP1B1 |
| stimulatory C-type lectin receptor signaling pathway | biological_process | SRC, NFKB1, FCER1G, PSMD9, MAP3K7, FYN, PSMD10, NRAS, KRAS, RELA, PAK1, KLRK1 |
| strand displacement | biological_process | BRCA1, BRCA2, XRCC3, ATM |
| strand invasion | biological_process | XRCC3 |
| stress fiber assembly | biological_process | SRC, ITGB5, ITGB1, RHOA |
| stress-activated MAPK cascade | biological_process | NFKB1, CRYAB, MAP3K7, MAP2K7 |
| stress-activated protein kinase signaling cascade | biological_process | AKR1B1 |
| stress-induced mitochondrial fusion | biological_process | STOML2 |
| stress-induced premature senescence | biological_process | CDKN1A, SIRT1 |
| striatal medium spiny neuron differentiation | biological_process | INHBA |
| striated muscle cell development | biological_process | SDC1 |
| striated muscle cell differentiation | biological_process | AKT1, IGFBP5, RB1, KRAS |
| striated muscle contraction | biological_process | ARG2 |
| striatum development | biological_process | DRD2 |
| submandibular salivary gland formation | biological_process | CDC42 |
| substantia nigra development | biological_process | CDC42, ACTB, YWHAH, RHOA |
| substrate adhesion-dependent cell spreading | biological_process | SRC, AXL, EFNA1, FN1, ITGB3, ITGAV, LAMA5, RAC1, TYRO3, TEK, LAMC1 |
| substrate-dependent cell migration | biological_process | ITGA2, VEGFC |
| suckling behavior | biological_process | OXTR |
| sulfate assimilation | biological_process | TXN |
| sulfate transmembrane transport | biological_process | SLC26A8 |
| sulfate transport | biological_process | SLC26A8 |
| sulfation | biological_process | SULT1E1 |
| sulfur amino acid metabolic process | biological_process | GCLC |
| sulfur compound metabolic process | biological_process | CHST6, CHST2 |
| superior temporal gyrus development | biological_process | GSK3B |
| superoxide anion generation | biological_process | SOD1, EDN1 |
| superoxide metabolic process | biological_process | NOS2, SOD1 |
| suppression by virus of host apoptotic process | biological_process | BCL2L1 |
| surfactant homeostasis | biological_process | VEGFA, PLA2G4A |
| susceptibility to natural killer cell mediated cytotoxicity | biological_process | CADM1 |
| swimming behavior | biological_process | IDO1 |
| sympathetic ganglion development | biological_process | CTNNB1, NRP1, NRP2, SEMA3A |
| sympathetic nervous system development | biological_process | GATA3, NRP1, TP63, SEMA3A |
| sympathetic neuron projection extension | biological_process | NRP1, NRP2, SEMA3A |
| sympathetic neuron projection guidance | biological_process | NRP1, NRP2, SEMA3A |
| synapse assembly | biological_process | CDH1, WNT5A, DRD2, BDNF, WNT7A, PTEN, NRG1, SPOCK2 |
| synapse maturation | biological_process | PTEN |
| synapse organization | biological_process | CTNNB1, WNT7A, SNCG |
| synapsis | biological_process | MLH1 |
| synaptic transmission, cholinergic | biological_process | APOE, HRH4 |
| synaptic transmission, dopaminergic | biological_process | DRD2, CRHBP, CRH, PARK7 |
| synaptic transmission, GABAergic | biological_process | RAC1 |
| synaptic vesicle maturation | biological_process | SYP |
| synaptic vesicle membrane organization | biological_process | SYP |
| synaptic vesicle recycling | biological_process | WNT7A |
| synaptic vesicle transport | biological_process | CTNNB1, DPYSL2 |
| synaptonemal complex disassembly | biological_process | PLK1 |
| syncytium formation | biological_process | ERVW-1 |
| T cell activation | biological_process | HSPD1, PRLR, TGFB1, CD4, FYN, ADA, IL6, SMAD3, FOXP3 |
| T cell activation involved in immune response | biological_process | F2RL1 |
| T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological_process | ICAM1 |
| T cell antigen processing and presentation | biological_process | ICAM1 |
| T cell apoptotic process | biological_process | FASLG |
| T cell chemotaxis | biological_process | CCL3, CXCR3, CXCL10, CXCL16 |
| T cell costimulation | biological_process | SRC, CD40LG, PIK3R1, AKT1, HLA-DRB1, LGALS1, CTLA4, PIK3CA, MTOR, CD4, FYN, CCL21, HLA-DQA1, HLA-DPB1, CDC42, RAC1, PAK1, CCL19, HLA-DRA, KLRK1 |
| T cell differentiation | biological_process | BCL2, EGR1, GATA3, KIT, LEP, CTNNB1, LEPR, TGFB1, CD4, PTPN22, DLL4, IL2, TBX21 |
| T cell differentiation in thymus | biological_process | BCL2, GATA3, CTNNB1, WNT1, ADAM17, WNT4 |
| T cell differentiation involved in immune response | biological_process | FCER1G |
| T cell homeostasis | biological_process | BCL2, CASP3, FAS, TGFB1, BCL2L11, IL2RA, FOXP3 |
| T cell homeostatic proliferation | biological_process | BAX |
| T cell lineage commitment | biological_process | BCL2 |
| T cell mediated cytotoxicity | biological_process | CADM1, MICA, MICB |
| T cell mediated immunity | biological_process | FOXP3, JAG1 |
| T cell proliferation | biological_process | IL23A |
| T cell proliferation involved in immune response | biological_process | LILRB1 |
| T cell receptor signaling pathway | biological_process | GATA3, MAPK1, PIK3R1, NFKB1, HLA-DRB1, PIK3CA, PSMD9, IFNG, MAP3K7, CD4, FYN, TNFRSF21, PSMD10, HLA-DQA1, HLA-DPB1, PTEN, RELA, PAK1, STOML2, FOXP3, HLA-DRA |
| T cell selection | biological_process | CD4, CD74 |
| T follicular helper cell differentiation | biological_process | FOXP1 |
| t-circle formation | biological_process | XRCC3 |
| T-helper 1 cell activation | biological_process | HMGB1 |
| T-helper 1 cell differentiation | biological_process | HMGB1 |
| T-helper 1 cell lineage commitment | biological_process | STAT6, IL4 |
| T-helper 1 type immune response | biological_process | IL12B, HLA-DRB1, TLR4, IL18 |
| T-helper 17 cell chemotaxis | biological_process | CCR2 |
| T-helper 17 cell lineage commitment | biological_process | IL6 |
| T-helper 2 cell cytokine production | biological_process | IL4 |
| T-helper 2 cell differentiation | biological_process | GATA3, IL4 |
| T-helper cell differentiation | biological_process | IL12B, PTGER4, ATP7A |
| tachykinin receptor signaling pathway | biological_process | TACR2, TACR1 |
| targeting of mRNA for destruction involved in RNA interference | biological_process | DICER1 |
| taste bud development | biological_process | NTF4 |
| telencephalon cell migration | biological_process | CXCL12, CXCR4 |
| telencephalon development | biological_process | BMP4, FAS, OXTR, HES5 |
| telencephalon regionalization | biological_process | BMP4 |
| telomere capping | biological_process | HIST3H3 |
| telomere maintenance | biological_process | PCNA, APEX1, TERT, ATM |
| telomere maintenance via recombination | biological_process | PCNA, BRCA2, XRCC3 |
| telomere maintenance via telomerase | biological_process | TERT, ATM |
| temperature homeostasis | biological_process | STAT3, DRD2, GPX1, FOXO1 |
| tendon cell differentiation | biological_process | BMP4 |
| tertiary branching involved in mammary gland duct morphogenesis | biological_process | WNT4 |
| testosterone biosynthetic process | biological_process | HSD17B1, HSD17B3, AKR1C3, STAR |
| tetrahydrofolate interconversion | biological_process | MTHFR |
| tetrahydrofolate metabolic process | biological_process | MTHFR |
| thalamus development | biological_process | SLC6A4, PTN, SRD5A1 |
| thermoception | biological_process | TRPV1 |
| thigmotaxis | biological_process | ID2 |
| thiocyanate metabolic process | biological_process | LPO |
| thorax and anterior abdomen determination | biological_process | WT1 |
| thrombin-activated receptor signaling pathway | biological_process | F2R, HPGD, F2RL1 |
| thymic T cell selection | biological_process | GATA3 |
| thymocyte apoptotic process | biological_process | BCL2L11, BAX |
| thymus development | biological_process | BCL2, GATA3, MAPK1, CTNNB1, BRAF, SOD1, BCL2L11 |
| thyroid gland development | biological_process | MAPK1, BRAF, SMAD3 |
| thyroid hormone metabolic process | biological_process | SLCO4A1 |
| thyroid hormone transport | biological_process | SLCO4A1 |
| thyroid-stimulating hormone-secreting cell differentiation | biological_process | WNT4 |
| Tie signaling pathway | biological_process | ANGPT2, TEK, ANGPT1 |
| tissue development | biological_process | BMP4, GATA2, WT1, NR5A2, NR5A1, POSTN |
| tissue homeostasis | biological_process | AKR1B1, ITGB1 |
| tissue morphogenesis | biological_process | SMAD4, NODAL |
| tissue regeneration | biological_process | CCNB1, NOTCH1, IGFBP1, SOX2, TIMP3 |
| tissue remodeling | biological_process | MMP14, IL23A |
| tolerance induction | biological_process | C3, FOXP3 |
| tolerance induction to self antigen | biological_process | TGFB1, FOXP3 |
| toll-like receptor 2 signaling pathway | biological_process | LGALS9, TLR2 |
| toll-like receptor 3 signaling pathway | biological_process | TLR3 |
| toll-like receptor 4 signaling pathway | biological_process | LGALS9, TLR4, ITGB2 |
| toll-like receptor 9 signaling pathway | biological_process | TLR9 |
| toll-like receptor signaling pathway | biological_process | TLR2, TLR4, TLR3, CTSB, TLR9 |
| toll-like receptor TLR1:TLR2 signaling pathway | biological_process | TLR2 |
| toll-like receptor TLR6:TLR2 signaling pathway | biological_process | CD36, TLR2 |
| tongue morphogenesis | biological_process | BMP4 |
| TOR signaling | biological_process | GATA3, MTOR, EIF4EBP1 |
| toxin biosynthetic process | biological_process | CYP1A2 |
| toxin metabolic process | biological_process | CYP1A2, CYP1A1, CYP1B1 |
| toxin transport | biological_process | CASP1, ARID1A, NRP1 |
| trabecula morphogenesis | biological_process | RHOA |
| trabecular meshwork development | biological_process | CYP1B1 |
| trachea development | biological_process | BMP4 |
| trachea formation | biological_process | BMP4, MAPK1, CTNNB1 |
| trachea morphogenesis | biological_process | CTNNB1 |
| transcription from RNA polymerase II promoter | biological_process | EGR1, GATA3, STAT3, CDX1, HMGA2, ATF2, NFKB1, HMGA1, AHR, NOTCH1, GATA2, USF1, HOXA10, WT1, SOX2, ESR1, JUN, CLOCK, TP53, MYC, MEIS1, NR5A2, KLF11, FOS, TGFB1I1, NR3C1, COPS5, RUNX3, YBX1, RELA, FOXL2, HIF1A, NR5A1, SMAD2, NFE2L2, PPARA, NFKB2, POU5F1, SMAD4, TP63, GATA6, PAX2, USF2, DLX5, GATA5, MAF, CREB3L1 |
| transcription initiation from RNA polymerase II promoter | biological_process | YAP1, PPARG, AR, NOTCH1, VDR, ESR1, NR5A2, NR3C1, PGR, NR5A1, ESR2, PPARA, KAT2B, NR0B2, NOTCH4 |
| transcription, DNA-templated | biological_process | FGFR1, EGR1, TXN, GATA3, YAP1, CCND1, BCL6, STAT3, NR2F2, DNMT1, CDX1, HMGA2, PPARG, MAPK1, APEX1, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, AHR, NOTCH1, ID1, FASLG, VDR, COL4A2, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ZEB1, PTGER3, CHEK2, ESR1, JUN, CLOCK, MAP3K7, PRKCB, FSTL3, LTF, TP53, SUV39H1, MYC, BIRC5, ENO1, ERBB2, SMAD7, MEIS1, NR5A2, RB1, ARID1A, KLF11, NR3C1, KHDRBS3, PRDM1, PGR, IL33, C1QBP, RUNX3, YBX1, HDAC2, SMAD3, RELA, FOXL2, HIF1A, FOXP1, HES5, ATP1B4, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, NFKB2, POU5F1, KAT2B, HDAC1, FOXP3, EZH2, SIRT1, ID2, STAT4, SMAD4, TWIST1, NR0B2, ZNF366, CDKN2A, TP63, KLF10, GATA6, NAA15, SUV39H2, PAX2, USF2, DLX5, KLF9, IL16, PPRC1, TBPL2, NOTCH4, CHD5, NANOG, GATA5, TBX21, AHRR, MAF, FHIT, TET1, CREB3L1, SRA1, MBD2, PIAS3 |
| transcription, RNA-templated | biological_process | TERT |
| transcription-coupled nucleotide-excision repair | biological_process | PCNA, XRCC1, COPS5 |
| transcytosis | biological_process | SRC |
| transdifferentiation | biological_process | LIF, SMAD3, AGER |
| transferrin transport | biological_process | TF |
| transformation of host cell by virus | biological_process | INSR |
| transforming growth factor beta receptor signaling pathway | biological_process | SRC, HPGD, ID1, ENG, ITGB5, CCL2, ITGB1, JUN, TGFB1, MAP3K7, APOA1, PDGFA, SMAD7, CLDN5, MSTN, FOS, GDF9, FSHB, TGFB2, PTK2, SMAD3, SMAD2, SMAD4, AMHR2, KLF10, GDF15, RHOA |
| transforming growth factor beta receptor signaling pathway involved in primitive streak formation | biological_process | NODAL |
| translation | biological_process | AKT1, COPS5, EIF3E, RPL41 |
| translational initiation | biological_process | COPS5, EIF3E, RPL41 |
| translesion synthesis | biological_process | PCNA |
| transmembrane receptor protein serine/threonine kinase signaling pathway | biological_process | BMPR1B, AMHR2 |
| transmembrane receptor protein tyrosine kinase signaling pathway | biological_process | MET, KIT, ERBB3, KDR, CSF1, FLT4, PDGFRA, JAK1, TYK2, FLT1, FLT3, NTF4, INSR, EGFR, IGF1R, NGF, ERBB2, CD4, FYN, CSF1R, NRG1, NTRK2, TEK, MST1R, ANGPT1 |
| transmembrane receptor protein tyrosine phosphatase signaling pathway | biological_process | PTN |
| transmembrane transport | biological_process | BCL2, GJA1, CFTR, SLC6A4, CLCN3, AZGP1, SLC6A2, APOA1, SLC22A23, ABCC4, ABCB1, SLC26A8, TRPV1 |
| transmission of nerve impulse | biological_process | SOD1 |
| transport | biological_process | ATP5A1, CETP, PTGDS, FOLR1, IGF2R, GJA1, CFTR, PIK3R1, CD36, AKT1, SLC6A4, AR, CLCN3, RBP1, PAEP, SLC6A2, AQP2, STAR, AFM, ATP5B, ACTN4, SERPINA6, APOA1, LTF, APOA2, APOE, SLC22A23, CCDC22, ABCC4, AQP8, CP, TF, GC, HPX, ABCB1, SYP, SMAD3, ATP1B4, S100A13, ATP7A, STX5, CSE1L, ABCG2, SLC26A8, TRPV1, AQP5, P2RX3, SLCO2A1, SLCO4A1, IPO13 |
| TRIF-dependent toll-like receptor signaling pathway | biological_process | TLR4, TLR3 |
| trigeminal ganglion development | biological_process | NRP1, SEMA3A |
| trigeminal nerve morphogenesis | biological_process | NRP1 |
| trigeminal nerve structural organization | biological_process | NRP1, SEMA3A |
| triglyceride catabolic process | biological_process | LIPC, APOA1, APOE |
| triglyceride homeostasis | biological_process | CETP, LIPC, APOA1, SCARB1 |
| triglyceride metabolic process | biological_process | CETP, LIPC, CYP2E1, APOA2, APOE, GPX1, CAT |
| triglyceride mobilization | biological_process | SIRT1 |
| triglyceride transport | biological_process | CETP, CD36 |
| triglyceride-rich lipoprotein particle remodeling | biological_process | APOA2 |
| trophectodermal cell differentiation | biological_process | ADA, NODAL |
| trophectodermal cellular morphogenesis | biological_process | NODAL |
| trophoblast giant cell differentiation | biological_process | NR2F2, LIF, SOCS3, SNAI1, PRDM1 |
| tryptophan catabolic process | biological_process | IDO1 |
| tryptophan catabolic process to kynurenine | biological_process | IDO1 |
| tryptophan metabolic process | biological_process | ATP7A |
| tube closure | biological_process | WNT5A |
| tube development | biological_process | ITGB3 |
| tube formation | biological_process | VEGFA, NOTCH1, BCL2L11 |
| tube morphogenesis | biological_process | GATA6, WNT4 |
| tubulin complex assembly | biological_process | CRYAB |
| tumor necrosis factor production | biological_process | TLR9 |
| tumor necrosis factor secretion | biological_process | HMGB1 |
| tumor necrosis factor-mediated signaling pathway | biological_process | CD40LG, TNFRSF1A, TNFRSF1B, CD40, FAS, PSMD9, TNF, TNFRSF11B, TNFRSF21, PSMD10, LTA, TNFSF13B, ADAM17 |
| type 2 immune response | biological_process | BCL6, IL10, IL33, IL4, IL18 |
| type B pancreatic cell development | biological_process | BMP4, WNT5A, BMP6 |
| type B pancreatic cell differentiation | biological_process | GATA6 |
| type B pancreatic cell proliferation | biological_process | IGFBP3, IGFBP5, IGFBP4 |
| type I interferon signaling pathway | biological_process | EGR1, JAK1, TYK2, HLA-C, HLA-E, HLA-G, HLA-A, HLA-B, ISG20 |
| Type II pneumocyte differentiation | biological_process | GATA6 |
| type IV hypersensitivity | biological_process | GATA3 |
| tyrosine catabolic process | biological_process | GSTZ1 |
| tyrosine phosphorylation of STAT protein | biological_process | F2R, LEP |
| tyrosine phosphorylation of Stat3 protein | biological_process | LIF |
| tyrosine phosphorylation of Stat5 protein | biological_process | IL15 |
| ubiquitin-dependent protein catabolic process | biological_process | UCHL1, PSMD9 |
| ubiquitin-dependent SMAD protein catabolic process | biological_process | TGFB1I1, WNT1 |
| UDP-glucose catabolic process | biological_process | GALT |
| umbilical cord morphogenesis | biological_process | HEY1 |
| urate biosynthetic process | biological_process | PNP |
| urate metabolic process | biological_process | ABCG2 |
| urea cycle | biological_process | ARG2 |
| ureter development | biological_process | PAX2 |
| ureter epithelial cell differentiation | biological_process | BMP4 |
| ureter maturation | biological_process | GATA3, PAX2 |
| ureter smooth muscle cell differentiation | biological_process | BMP4 |
| ureteric bud development | biological_process | BCL2, FGFR1, BMP4, FGFR2, EPCAM, SDC4, SDC1, WT1, TGFB1, SMAD7, CAT, ARG2, SMAD3, SMAD2 |
| ureteric bud elongation | biological_process | HNF1B |
| ureteric bud formation | biological_process | GATA3, GREM1 |
| urinary bladder development | biological_process | WNT5A, TP63 |
| urinary bladder smooth muscle contraction | biological_process | PTGER3, P2RX3 |
| urogenital system development | biological_process | GATA2, AMH, PAX2, SRD5A1 |
| urokinase plasminogen activator signaling pathway | biological_process | PLAUR |
| uterine wall breakdown | biological_process | TGFB2 |
| uterus development | biological_process | SRC, GATA3, WNT5A, HOXA10, HOXA11, ESR1, WNT7A, FOXL2, SMAD4 |
| uterus morphogenesis | biological_process | WNT7A |
| UTP biosynthetic process | biological_process | NME1 |
| UV protection | biological_process | GPX1, CAT |
| UV-damage excision repair | biological_process | SIRT1 |
| V(D)J recombination | biological_process | HMGB1, ATM |
| vagina development | biological_process | WNT5A, AXL, ESR1, TYRO3, BAX |
| vascular endothelial growth factor production | biological_process | HIF1A |
| vascular endothelial growth factor receptor signaling pathway | biological_process | CRK, SRC, VEGFA, PIK3R1, KDR, FLT4, AXL, FLT1, CCL2, PIK3CA, VEGFC, ITGB3, HSP90AA1, ITGAV, HSPB1, FYN, NRP1, FIGF, NRP2, CDC42, RAC1, PTK2, ACTB, RHOA |
| vascular endothelial growth factor receptor-1 signaling pathway | biological_process | FLT1 |
| vascular endothelial growth factor receptor-2 signaling pathway | biological_process | PDCD6 |
| vascular endothelial growth factor signaling pathway | biological_process | VEGFA, FLT4, FLT1, FLT3, NRP1, NRP2 |
| vascular smooth muscle cell development | biological_process | ADM |
| vascular transport | biological_process | GJA1 |
| vascular wound healing | biological_process | HPSE, ADIPOR2 |
| vasculature development | biological_process | BMP4, CTNNB1, FLT4, PIK3CA, HIF1A, NODAL |
| vasculogenesis | biological_process | YAP1, VEGFA, CTNNB1, KDR, ENG, WT1, ADM, PTK2, NTRK2 |
| vasculogenesis involved in coronary vascular morphogenesis | biological_process | NOTCH1 |
| vasoconstriction | biological_process | SLC6A4, EDNRA, EDN1 |
| vasodilation | biological_process | APOE, GPX1 |
| VEGF-activated neuropilin signaling pathway | biological_process | VEGFA, NRP1 |
| VEGF-activated neuropilin signaling pathway involved in axon guidance | biological_process | NRP1 |
| vein smooth muscle contraction | biological_process | EDN1 |
| venous blood vessel morphogenesis | biological_process | ENG |
| venous endothelial cell differentiation | biological_process | NOTCH1 |
| ventral spinal cord interneuron differentiation | biological_process | GATA2 |
| ventral spinal cord interneuron fate commitment | biological_process | DLL4 |
| ventral trunk neural crest cell migration | biological_process | NRP1, SEMA3A |
| ventricular cardiac muscle cell development | biological_process | CCNB1 |
| ventricular cardiac muscle cell differentiation | biological_process | NRG1 |
| ventricular cardiac muscle tissue morphogenesis | biological_process | FGFR2, SMAD7 |
| ventricular septum development | biological_process | GATA3, CYR61, PRDM1 |
| ventricular septum morphogenesis | biological_process | NOTCH1, SMAD7, HEY1 |
| ventricular trabecula myocardium morphogenesis | biological_process | NOTCH1, NRG1, DLL4 |
| ventricular zone neuroblast division | biological_process | FGFR1, FGFR2 |
| very-low-density lipoprotein particle clearance | biological_process | APOE |
| very-low-density lipoprotein particle remodeling | biological_process | CETP, LIPC, APOE |
| vesicle docking | biological_process | STX5 |
| vesicle docking involved in exocytosis | biological_process | CFTR |
| vesicle fusion | biological_process | STX5 |
| vesicle fusion with Golgi apparatus | biological_process | STX5 |
| vesicle transport along actin filament | biological_process | ACTN4 |
| vesicle-mediated transport | biological_process | KALRN, STX5 |
| vestibulocochlear nerve formation | biological_process | PAX2 |
| vestibulocochlear nerve structural organization | biological_process | NRP1 |
| viral entry into host cell | biological_process | AXL, ITGA2, ITGB5, NCAM1, ITGB6, MRC1, ITGB3, ITGB1, ITGAV, CTSB, ICAM1, GAS6, TYRO3, NECTIN1, SCARB1, NECTIN4 |
| viral genome replication | biological_process | CCL2, CXCR6, GAS6 |
| viral life cycle | biological_process | PCSK5 |
| viral process | biological_process | MSH6, H2AFX, HSPD1, SRC, STAT3, TNFRSF1A, FBLN1, MAPK1, PIK3R1, VIM, SHC1, HMGA1, KRT19, KDR, CCR5, PDGFRA, AXL, IL6ST, ITGA2, ITGB5, KRT7, HLA-C, NCAM1, IL2RB, VCAM1, ITGB6, MRC1, HLA-A, CCR2, ITGB3, ITGB1, ITGAV, TP53, SUV39H1, APOA2, CD4, FYN, RB1, HLA-B, ICAM1, HPX, MMP1, C1QBP, RELA, GAS6, TYRO3, BAX, CXCR4, SET, KAT2B, HDAC1, NECTIN1, SIRT1, SCARB1, MICA, IL16, NECTIN4, MICB, HLA-DRA, RHOA |
| viral transcription | biological_process | RPL41 |
| virion assembly | biological_process | APOE |
| visceral serous pericardium development | biological_process | WT1 |
| visual learning | biological_process | KIT, DRD2, BRAF, MTOR, ITGB1, SGK1, KRAS, HIF1A |
| visual perception | biological_process | CDH3, TIMP3, COL18A1, PAX2, DLL4, CYP1B1 |
| vitamin A metabolic process | biological_process | RBP1 |
| vitamin D catabolic process | biological_process | CYP24A1 |
| vitamin D metabolic process | biological_process | CYP11A1, GC, CYP1A1, CYP24A1 |
| vitamin D receptor signaling pathway | biological_process | VDR, CYP24A1 |
| vitamin metabolic process | biological_process | CYP26A1, CYP24A1 |
| vitamin transmembrane transport | biological_process | SCARB1 |
| vitamin transport | biological_process | AFM, APOA1, GC |
| voluntary musculoskeletal movement | biological_process | MTOR |
| water transport | biological_process | AQP2, AQP8, AQP5 |
| white fat cell differentiation | biological_process | PPARG, SIRT1 |
| Wnt signaling pathway | biological_process | GSK3B, CCND1, WNT5A, CTNNB1, WNT2, DRD2, WNT7A, TGFB1I1, DKK1, WNT1, WNT4, SFRP4 |
| Wnt signaling pathway involved in dorsal/ventral axis specification | biological_process | EGF |
| Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological_process | WNT5A, WNT1 |
| Wnt signaling pathway involved in somitogenesis | biological_process | DKK1 |
| Wnt signaling pathway involved in wound healing, spreading of epidermal cells | biological_process | WNT7A |
| Wnt signaling pathway, calcium modulating pathway | biological_process | WNT5A, CTNNB1, MAP3K7, PLCB1, PLCB3 |
| Wnt signaling pathway, planar cell polarity pathway | biological_process | WNT5A, PSMD9, PSMD10, WNT1, CDC42, RAC1, RHOA |
| wound healing | biological_process | FGF2, BMP4, WNT5A, ALOX15, OPRM1, ERBB3, CASP3, SDC4, PDGFRA, ENG, ITGA2, SPARC, SDC1, CDH3, TNC, MTOR, MMP12, FN1, ITGB3, TGFB1, TIMP1, PDGFA, ERBB2, WNT7A, IL1B, PLAU, IGF2, SERPINB2, IL6, TGFB2, SMAD3, NRG1, HPSE, PAK1, PPARA, IL24, SCARB1, CX3CL1, POSTN, DCN |
| wound healing involved in inflammatory response | biological_process | HMOX1 |
| wound healing, spreading of cells | biological_process | RHOC, CYR61, RHOA |
| wound healing, spreading of epidermal cells | biological_process | MMP12, ADAM17 |
| xanthine biosynthetic process | biological_process | ADA |
| xanthine catabolic process | biological_process | XDH |
| xenobiotic catabolic process | biological_process | GSTM1 |
| xenobiotic metabolic process | biological_process | AHR, GSTP1, NAT2, CYP2B6, PTGS1, CYP2C19, CYP2E1, CYP1A2, EPHX1, AKR1C1, CYP1B1 |
| xenobiotic transport | biological_process | ABCB1, ABCG2 |
| xenophagy | biological_process | ANXA5, MSTN, CLDN7 |
| zygotic specification of dorsal/ventral axis | biological_process | SMAD2 |
| zymogen activation | biological_process | MMP14 |
| A band | cellular_component | KAT2B |
| acrosomal membrane | cellular_component | BSG |
| acrosomal vesicle | cellular_component | KIT, NOTCH1, DRD2, CTNNA1, ITGB1, SPINK1, TRIM36, LOXL1, VEZT |
| actin cap | cellular_component | CALD1 |
| actin cytoskeleton | cellular_component | CRK, PGM1, CDH1, CFL1, CTNNA1, ACTN4, KALRN, STOML2, ADAM17, DAPK1, Sep-09, CALD1 |
| actin filament | cellular_component | SRC, FYN, RAC1, TEK, AIF1 |
| actin filament bundle | cellular_component | CRYAB |
| activin A complex | cellular_component | INHBA |
| activin responsive factor complex | cellular_component | SMAD2, SMAD4 |
| actomyosin | cellular_component | KAT2B |
| Ada2/Gcn5/Ada3 transcription activator complex | cellular_component | MAP3K7, KAT2B |
| adherens junction | cellular_component | CTNNB1, NOTCH1, CTNNA1, ITGB1, NECTIN1, JAG1, NECTIN4, VEZT |
| aggresome | cellular_component | CDH1, CLU |
| AIM2 inflammasome complex | cellular_component | CASP1 |
| alpha9-beta1 integrin-ADAM8 complex | cellular_component | ADAM8 |
| alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex | cellular_component | VCAM1, ADAM8 |
| alphav-beta3 integrin-IGF-1-IGF1R complex | cellular_component | IGF1, ITGB3, ITGAV, IGF1R |
| alphav-beta3 integrin-vitronectin complex | cellular_component | ITGB3 |
| anchored component of external side of plasma membrane | cellular_component | FOLR1 |
| anchored component of membrane | cellular_component | FOLR1, TDGF1, NCAM1, EFNA1, PLAUR, ULBP2 |
| anchored component of plasma membrane | cellular_component | FOLR1, EFNA1, CP, ULBP2 |
| angiogenin-PRI complex | cellular_component | ANG |
| AP-2 adaptor complex | cellular_component | EGFR |
| apical cortex | cellular_component | HAMP |
| apical dendrite | cellular_component | CLU, FAS |
| apical junction complex | cellular_component | CDH1, CTNNB1, NECTIN3, RHOA |
| apical part of cell | cellular_component | CD36, CTNNB1, VCAM1, CA2, PLAT, AQP8, CDC42, JAG1 |
| apical plasma membrane | cellular_component | FOLR1, IGFBP2, GJA1, CFTR, CD36, EPCAM, ERBB3, NOTCH1, CLCN3, MUC1, IL6R, FAS, TDGF1, OXTR, AQP2, FN1, HSP90AA1, ANXA1, ERBB2, CLDN4, PROM1, CTSB, TF, PTEN, PTK2, NRG1, TEK, TLR9, NOD1, ADAM17, ABCG2, JAG1, AQP5, KISS1, MUC17, STC1 |
| apicolateral plasma membrane | cellular_component | CLDN5, CLDN4, CLDN3, CLDN7 |
| ARC complex | cellular_component | DICER1 |
| aryl hydrocarbon receptor complex | cellular_component | AHR |
| autophagosome | cellular_component | IL1B, GABARAPL1 |
| autophagosome membrane | cellular_component | GABARAPL1 |
| axolemma | cellular_component | NRG1 |
| axon | cellular_component | GSK3B, MME, MAPK1, SERPINF1, DRD2, UCHL1, TNFRSF1B, ITGA2, CNTF, IL1R1, COMT, CA2, CYP17A1, TGFB1, NRP1, TNFRSF21, SNCG, GC, TGFB2, NRG1, DICER1, PARK7, NTRK2, DPYSL2, PAK1, GHRL, FKBP4, NECTIN1, AGER, GPER1, ADAM22, UCN, P2RX3, CRHR2, SEMA3A, CADM2, OLFM1, LPAR3 |
| axon cytoplasm | cellular_component | UCHL1, SOD1, HIF1A |
| axon hillock | cellular_component | SERPINF1, AURKA |
| axon terminus | cellular_component | ANXA5, DRD2, ITGA2, CRHBP, CCL2, NTRK2, GPER1, UCN, CRHR2 |
| axonal growth cone | cellular_component | L1CAM, FKBP4, LIMK1, OLFM1 |
| axoneme | cellular_component | KIFAP3, Sep-09 |
| azurophil granule | cellular_component | MPO, OLFM4 |
| B cell receptor complex | cellular_component | CD79A |
| BAF-type complex | cellular_component | ARID1A |
| basal lamina | cellular_component | FN1, ANG, LAMA5 |
| basal part of cell | cellular_component | ITGA6, ITGA2, TF, EDN1 |
| basal plasma membrane | cellular_component | ITGA6, MET, CLDN4, TF, TEK, AGER, AQP5 |
| basement membrane | cellular_component | ITGA6, FBLN1, SERPINF1, COL4A2, LAMA1, SPARC, PTN, TNC, TIMP3, COL18A1, FN1, ITGB1, TIMP1, LAMA5, ANXA2, COL4A1, LOXL1, LAMC2, SMOC2, NTN4, LAMC1 |
| basolateral plasma membrane | cellular_component | ITGA6, ITGA3, FOLR1, CFTR, CTNNB1, HPGD, EPCAM, ERBB3, IL6R, LEPR, LPO, AQP2, CA2, HSP90AA1, EGFR, ANXA1, ERBB2, ABCC4, ANXA2, CLDN7, TEK, TLR9, NOD2, ATP7A, NOD1, CADM1 |
| BAX complex | cellular_component | BAX |
| Bcl-2 family protein complex | cellular_component | BCL2L1, BAX, MCL1 |
| Bcl3/NF-kappaB2 complex | cellular_component | NFKB2 |
| beta-catenin destruction complex | cellular_component | GSK3B, CTNNB1 |
| beta-catenin-TCF complex | cellular_component | CTNNB1 |
| beta-catenin-TCF7L2 complex | cellular_component | CTNNB1 |
| bicellular tight junction | cellular_component | CCND1, CTNNB1, EPCAM, CLDN5, CLDN4, CLDN3, CLDN7 |
| BIM-BCL-2 complex | cellular_component | BCL2L11 |
| BIM-BCL-xl complex | cellular_component | BCL2L11 |
| blood microparticle | cellular_component | CLU, HSPA6, C4A, PON1, AFM, FN1, TGFB1, A2M, FGA, AHSG, APOA1, BCHE, APOA2, APOE, C3, CP, HP, KRT1, TF, APCS, GC, HPX, C4BPA, A1BG, ACTB |
| BRCA1-A complex | cellular_component | BRCA1 |
| BRCA1-BARD1 complex | cellular_component | BRCA1 |
| BRCA2-MAGE-D1 complex | cellular_component | BRCA2 |
| brush border | cellular_component | MME, FOLR1, ACTN4 |
| brush border membrane | cellular_component | FOLR1, CD36, PTGER3, HSP90AA1, ATP7A, PEMT |
| C-fiber | cellular_component | CCL2 |
| Cajal body | cellular_component | ISG20 |
| catenin complex | cellular_component | CDH1, CTNNB1, CTNNA1, SMAD7, NECTIN1 |
| catenin-TCF7L2 complex | cellular_component | CTNNB1 |
| caveola | cellular_component | SRC, F2R, MAPK1, FASLG, HMOX1, SELE, NOS3, PTGS2, INSR, CTSB, SCARB1 |
| CCR4-NOT complex | cellular_component | TOB1 |
| CD40 receptor complex | cellular_component | CD40 |
| CD95 death-inducing signaling complex | cellular_component | FAS |
| cell | cellular_component | OPRM1, CXCL13, CCL19, CCL7, HAMP, CPB2, OLFM1, NPY |
| cell body | cellular_component | GSK3B, BRAF, IL6ST, TACR1, COMT, NRG1, PARK7, GABARAPL1 |
| cell body fiber | cellular_component | SRD5A2, CRHR2, SRD5A1 |
| cell cortex | cellular_component | FGFR2, CTNNB1, FGF1, FGA, ANXA2, PTK2, LAMC2, RHOA |
| cell junction | cellular_component | CDH1, ITGA3, GJA1, CTNNB1, EPCAM, KDR, CTNNA1, PECAM1, ITGB3, ITGB1, ACTN4, CLDN5, CLDN4, TGFB1I1, CLDN3, CLDN7, ADA, SYP, XRCC4, COPS5, PTK2, BCL2L1, PLAUR, CXCR4, TEK, PAK1, NECTIN1, GPER1, NECTIN3, CADM1, TRPV1, PTPRR, NECTIN4, CADM2, OLFM1, VEZT, RHOA |
| cell leading edge | cellular_component | VIM, CXCR4 |
| cell periphery | cellular_component | ITGA3, CTNNB1, KRT19, NOTCH1, TACR1, FYN, CDC42, RHOA |
| cell pole | cellular_component | ASTN2 |
| cell projection | cellular_component | ITGA3, VIM, ANXA5, CFL1, SPP1, S100P, ITGA2, MDK, L1CAM, AURKA, ITGB3, ITGB1, CYP17A1, ANXA1, ANGPT2, PROM1, SPRY2, CDC42, RAC1, PTEN, PLAUR, PAK1, AIF1, FKBP4, GPER1, ADAM22, TRPV1, CX3CL1, CADM2, OLFM1, RHOA |
| cell projection cytoplasm | cellular_component | AKR1B1 |
| cell projection membrane | cellular_component | CTNNB1 |
| cell surface | cellular_component | HSPD1, ITGA6, VEGFA, MET, CD40LG, F2R, WNT5A, ITGA3, TNFRSF1A, FOLR1, FGFR2, IGF2R, HMGB1, CLU, CFTR, BGN, CD36, F3, DPP6, KIT, MIF, EPCAM, MBL2, NOTCH1, CLCN3, FASLG, SDC4, CCR5, CXCR3, CD40, AXL, ANXA4, ENG, PRLR, IL6R, ITGA2, ITGB5, SPARC, LGALS1, MMP7, IL1R1, CXCR2, HLA-C, CD44, LIPC, FAS, TDGF1, NCAM1, HLA-E, IL2RB, IL15, VCAM1, TIMP2, SDC1, TACR1, PTN, MRC1, FCER1G, HLA-A, L1CAM, CCR2, PTGER3, CCR9, ATP5B, GREM1, ITGB3, ITGB1, HSP90AA1, EGFR, ITGAV, CRYAB, TGFB1, ANXA1, FGA, PLAT, APOA1, LTF, TNF, PDGFA, TLR2, TLR4, CD4, WNT7A, NRP1, TLR3, CAPN5, ANXA2, PROM1, THBS1, CTSB, ITGB2, PLAU, ADA, TF, IL2RA, HLA-B, HLA-DRB1, ICAM1, CD74, HLA-DPB1, WNT1, CSF1R, ABCB1, CTSG, C1QBP, NTRK2, CXCR4, TEK, ADIPOQ, NOD2, MST1R, ADAM17, AGER, ADAM8, IL1RL1, SCARB1, MICA, CX3CL1, WNT4, KISS1R, FOLH1, MICB, SFRP4, NOTCH4, ULBP2, HLA-DRA, KLRK1, CCR7 |
| cell-cell adherens junction | cellular_component | CDH1, CTNNB1, CTNNA1, CDH3, OXTR, SMAD7, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
| cell-cell junction | cellular_component | GJA1, PIK3R1, KIT, AKT1, CTNNB1, CTNNA1, ITGB1, ACTN4, CLDN5, CDC42, TEK, PAK1, ADAM17, NECTIN3, CADM1 |
| cellular_component | cellular_component | NPTX2, CCDC22, HES5, XYLT2, PLA2G16, NUDT6 |
| centriolar satellite | cellular_component | PAX2 |
| centriole | cellular_component | HSPA6, AURKA, BIRC5 |
| centrosome | cellular_component | GSK3B, PCNA, APEX1, CTNNB1, CCNB1, NME1, ID1, BRCA2, AURKA, SMAD7, XRCC4, PLK1, BCL2L1, NFE2L2, KIFAP3, ID2, CEP85 |
| chiasma | cellular_component | MLH1 |
| chloride channel complex | cellular_component | CFTR |
| chromaffin granule | cellular_component | CLU |
| chromatin | cellular_component | H2AFX, HMGA2, HMGA1, RB1, PLK1, HDAC2, EIF3E, PARK7, ATP1B4, NFE2L2, HDAC1, SIRT1, SUV39H2, MAF, MBD2 |
| chromatin silencing complex | cellular_component | SUV39H1, SIRT1 |
| chromatoid body | cellular_component | CLOCK |
| chromosome | cellular_component | MSH6, H2AFX, MLH1, HMGB1, BRCA1, HMGA1, MKI67, CLOCK, SUV39H1, TERT, BIRC5, IL33, PRM1, PLK1, EHMT2, HIST3H3, HIST2H3A, SUV39H2 |
| chromosome passenger complex | cellular_component | AURKA, BIRC5 |
| chromosome, centromeric region | cellular_component | MKI67, SUV39H1, BIRC5, PLK1, DNMT3A, SUV39H2 |
| chromosome, telomeric region | cellular_component | H2AFX, CHEK2, TERT, ATM |
| chylomicron | cellular_component | APOA1, APOA2, APOE |
| ciliary basal body | cellular_component | AKT1, KIFAP3 |
| ciliary membrane | cellular_component | DRD2 |
| ciliary neurotrophic factor receptor complex | cellular_component | IL6R, IL6ST |
| ciliary tip | cellular_component | KIFAP3 |
| cilium | cellular_component | AURKA, ANXA1, PROM1, ESR2 |
| cis-Golgi network | cellular_component | PIK3R1 |
| clathrin coat | cellular_component | IGF2R |
| clathrin-coated endocytic vesicle | cellular_component | CTLA4, SFTPA1 |
| clathrin-coated endocytic vesicle membrane | cellular_component | WNT5A, HLA-DRB1, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
| clathrin-coated pit | cellular_component | HSPD1, SELE, TF |
| clathrin-coated vesicle | cellular_component | FOLR1 |
| cleavage furrow | cellular_component | ITGB1, RHOC, PLCD3, FSD1, RHOA |
| coated vesicle | cellular_component | HSPD1 |
| collagen trimer | cellular_component | MBL2, COL4A2, COL18A1, COL4A1, COL5A2, ADIPOQ, SFTPA1 |
| collagen type IV trimer | cellular_component | COL4A2, COL4A1 |
| collagen type V trimer | cellular_component | COL5A2 |
| collagen type VI trimer | cellular_component | DCN |
| condensed chromosome | cellular_component | MLH1, HMGB1, BRCA1, MKI67, XRCC4 |
| condensed chromosome kinetochore | cellular_component | BIRC5, PLK1 |
| condensed nuclear chromosome | cellular_component | H2AFX, MLH1, BRCA1, SUV39H1, KIFAP3 |
| condensed nuclear chromosome outer kinetochore | cellular_component | CCNB1, PLK1 |
| condensed nuclear chromosome, centromeric region | cellular_component | AURKA, PLK1 |
| connexin complex | cellular_component | GJA1 |
| contractile fiber | cellular_component | GJA1, CRYAB, HSPB1 |
| COP9 signalosome | cellular_component | ATP5A1, HSPA6, COPS5, STOML2, NOD2 |
| cornified envelope | cellular_component | ANXA1 |
| cortical actin cytoskeleton | cellular_component | CDH1, CLDN5 |
| cortical cytoskeleton | cellular_component | NOS2, SELE, ACTN4 |
| costamere | cellular_component | KRT19, SDC4 |
| CRD-mediated mRNA stability complex | cellular_component | YBX1 |
| CRLF-CLCF1 complex | cellular_component | CNTF |
| CSF1-CSF1R complex | cellular_component | CSF1, CSF1R |
| Cul4A-RING E3 ubiquitin ligase complex | cellular_component | CDKN1B |
| cyclin-dependent protein kinase activating kinase holoenzyme complex | cellular_component | HSPD1 |
| cyclin-dependent protein kinase holoenzyme complex | cellular_component | CCND1, CDKN1A |
| cyclin/CDK positive transcription elongation factor complex | cellular_component | RB1 |
| cytoplasm | cellular_component | GSK3B, MSH6, XDH, AKR1B1, CRK, BCL2, HSPD1, PGM1, FGFR1, AKR1D1, EGR1, SRC, TXN, CDH1, YAP1, CCND1, VEGFA, STAT3, NOS2, BMP4, DNMT1, PCNA, PLA2G4A, WNT5A, MME, PTGDS, PPARG, PRDX6, CCL5, MAPK1, FGFR2, IGF2R, HMGB1, LGALS3, CLU, GJA1, CFTR, BGN, APEX1, PIK3R1, ALOX15, CHI3L1, F3, IL10, KIT, IL12B, VIM, LEP, OPRM1, MIF, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, ATF2, HPGD, CFL1, BRCA1, CCL3, NFKB1, CASP1, AR, TOB1, WNT2, AHR, CDKN1B, NOTCH1, NME1, ACE, KDR, ID1, CASP3, PLCD1, RASSF2, CCR5, FLT4, CXCR3, UCHL1, CDKN1A, HSPA6, CDKN2A, CD40, BRAF, MUC1, CTNNA1, STIP1, PDGFRA, ANXA4, ENG, BRCA2, S100P, JAK1, SPARC, TYK2, LGALS1, FLT1, KRT7, CNTF, ENO2, GSTP1, TIA1, RBP1, GSTM1, CD44, KITLG, MAP2, NAT2, CD79A, FAS, CCL2, NCAM1, HSD17B1, HOXB2, IL15, IDO1, LIF, MMP14, SELP, STMN1, STAT6, HOXA10, IL1RN, SDC1, WT1, TACR1, IL11, PTN, MDK, COMT, BMP6, LPO, CDH3, PTGS1, BDNF, CMA1, ACP1, ARNT, FLT3, IL12A, NOS3, MTOR, GSTT1, SSTR1, SRD5A2, HSPA4, SOX2, IL13, ADM, SSTR5, PTGS2, TIMP3, ZEB1, CCR2, AKR1C3, PTGFR, MKI67, AKR1C2, PSMD9 |
| cytoplasmic dynein complex | cellular_component | BCL2L11 |
| cytoplasmic microtubule | cellular_component | CYP2A6, SAA1, BIRC5 |
| cytoplasmic ribonucleoprotein granule | cellular_component | CDC42, RAC1, ACTB |
| cytoplasmic side of plasma membrane | cellular_component | CDH1, KIT, ACP1, PTEN, PTPN22 |
| cytoplasmic stress granule | cellular_component | TIA1, YBX1 |
| cytoplasmic vesicle | cellular_component | FGFR1, PLA2G4A, PRDX6, FOLR1, FGFR2, IGFBP2, CLU, NOTCH1, DRD2, CLCN3, KDR, FASLG, MMP14, AQP2, ITGB1, ANG, ANXA1, SOD1, APOA1, TLR2, ERBB2, PDCD6, NRP1, IL1B, IL33, ADA, SYP, RAC1, COPS5, BCL2L1, CXCR4, TLR9, GABARAPL1, ATM, GPER1, TRIM36, VEZT, OVGP1 |
| cytoplasmic vesicle lumen | cellular_component | FASLG, ADA |
| cytoplasmic vesicle membrane | cellular_component | AQP2, ANXA1, GABARAPL1, YWHAH, GPER1 |
| cytoskeleton | cellular_component | SRC, MAPK1, VIM, CTNNB1, CCNB1, CFL1, CTNNA1, BRCA2, JAK1, TYK2, KITLG, MAP2, STMN1, NOS3, AURKA, HSPB1, BIRC5, LATS1, TPM3, TGFB1I1, NR3C1, SPRY2, KALRN, SNCG, PNP, KRT1, CDC42, PLK1, PTK2, BCL2L1, DPYSL2, ACTB, TEK, STOML2, NOD2, AIF1, FKBP4, GABARAPL1, GPER1, DAPK1, TRIM36, CEP85, Sep-09, FSD1, TMOD3, RHOA, CALD1 |
| cytosol | cellular_component | GCLC, GSK3B, XDH, AKR1B1, CRK, BCL2, HSPD1, PGM1, FGFR1, AKR1D1, SRC, TXN, YAP1, CCND1, STAT3, NOS2, PLA2G4A, F2R, PPARG, PRDX6, MAPK1, CLU, GJA1, CFTR, PIK3R1, CD36, ALOX15, VIM, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, HPGD, MTHFR, CCL3, SLC6A4, NFKB1, HMGA1, CASP1, AR, AHR, CDKN1B, NOTCH1, NME1, DRD2, CASP3, PLCD1, CXCR3, UCHL1, CDKN1A, HSPA6, CDKN2A, BRAF, CTNNA1, JAK1, EDNRA, GATA2, TYK2, ENO2, GSTP1, RBP1, GSTM1, HMOX1, NAT2, FAS, HSD17B1, IDO1, STMN1, STAT6, TYMP, TACR1, PIK3CA, COMT, FLT3, NOS3, MTOR, OXTR, GSTT1, MAT2A, HSPA4, SOX2, ADM, CCR2, AKR1C3, STAR, ALDH3A2, PSMD9, GSTZ1, AURKA, INSR, CA2, HSP90AA1, JUN, FGF1, CRYAB, RHOC, MAP3K7, A2M, SOD1, PRKCB, IL1A, APOA1, S100A6, TP53, APOA2, MYC, HSPB1, BIRC5, ENO1, LATS1, FYN, TPM3, SGK1, SMAD7, WNT7A, SOCS3, MAP2K7, NRP1, FOS, ANXA2, BCL2L11, SPRY2, KALRN, PSMD10, IL1B, PNP, GPX1, ADA, KRAS, GC, CAT, GALT, CDC42, XRCC4, RAC1, ADI1, C1QBP, PTEN, PLK1, PTK2, SMAD3, RELA, BCL2L1, DICER1, EIF3E, PARK7, NTRK2, HIF1A, FOXO1, DPYSL2, BAX, PLCB1, ACTB, S100A13, HSF |
| cytosolic aryl hydrocarbon receptor complex | cellular_component | AHR |
| cytosolic large ribosomal subunit | cellular_component | RPL41 |
| death-inducing signaling complex | cellular_component | CASP3, FAS |
| dendrite | cellular_component | GSK3B, MME, OPRM1, ANXA5, DRD2, IL6ST, CRHBP, CCL2, TACR1, COMT, MTOR, CCR2, APOE, BMPR1B, NRG1, DICER1, NTRK2, DPYSL2, PAK1, GPER1, TP63, UCN, CRHR2, SEMA3A, PIAS3 |
| dendrite cytoplasm | cellular_component | MAPK1, OPRM1, SOD1, ADA, GABARAPL1 |
| dendrite membrane | cellular_component | OPRM1, GABARAPL1 |
| dendritic shaft | cellular_component | GSK3B, CTNNB1, GPER1 |
| dendritic spine | cellular_component | GSK3B, DRD2, COMT, ITGB1, PTEN, NTRK2, P2RX3 |
| dendritic spine head | cellular_component | GPER1 |
| dendritic spine membrane | cellular_component | GPER1, TRPV1 |
| dense body | cellular_component | ACTB |
| dense core granule | cellular_component | CRHBP, SOD1 |
| dense core granule membrane | cellular_component | ADAM8 |
| discoidal high-density lipoprotein particle | cellular_component | APOA1 |
| DNA ligase IV complex | cellular_component | XRCC4 |
| DNA repair complex | cellular_component | ATM |
| DNA replication factor C complex | cellular_component | PCNA |
| DNA-dependent protein kinase-DNA ligase 4 complex | cellular_component | XRCC4 |
| dystrophin-associated glycoprotein complex | cellular_component | KRT19 |
| early endosome | cellular_component | HSPD1, F2R, MAPK1, IGF2R, HMGB1, GJA1, CFTR, CLCN3, KDR, LIPC, VCAM1, ANXA1, APOA1, APOA2, APOE, CD4, NRP1, TLR3, ANXA2, PTP4A3, TF, CXCR4, F2RL1, GPER1 |
| early endosome membrane | cellular_component | CFTR, CLCN3, HLA-C, HLA-E, HLA-G, HLA-A, EGFR, ANXA1, DKK1, HLA-B, RAC1 |
| early phagosome | cellular_component | TLR9 |
| egg coat | cellular_component | OVGP1 |
| elastic fiber | cellular_component | FBLN1 |
| endocytic vesicle | cellular_component | IGF2R, DRD2, CCL2, EGFR, APOA1, TF |
| endocytic vesicle lumen | cellular_component | SPARC, SAA1, HSP90AA1, APOA1, APOE, HP, HPX |
| endocytic vesicle membrane | cellular_component | WNT5A, CD36, HLA-DRB1, NOS3, WNT7A, HLA-DQA1, CD74, HLA-DPB1, WNT1, SCARB1, WNT4, HLA-DRA |
| endolysosome lumen | cellular_component | CTSB |
| endolysosome membrane | cellular_component | TLR3, TLR9 |
| endomembrane system | cellular_component | SLC6A4, JAK1, MTOR, PGRMC1, PGRMC2, BCL2L11, PCSK5 |
| endoplasmic reticulum | cellular_component | BCL2, PLA2G4A, PTGDS, CLU, GJA1, APEX1, CHI3L1, CYP19A1, OPRM1, ANXA5, NOTCH1, KDR, UCHL1, CYP2A6, HLA-DRB1, CRHBP, STS, HMOX1, HLA-C, HSD3B2, PLA2G2A, VCAM1, CYP2B6, PTN, PTGS1, FLT3, MTOR, HLA-A, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, ALDH3A2, CYP17A1, EGFR, PGRMC1, CYP2E1, SERPINA1, BCHE, TP53, APOE, CYP1A2, PDCD6, SGK1, FOS, TLR3, CYP26A1, PROM1, THBS1, AGR2, HLA-B, HLA-DQA1, CAT, CD74, HLA-DPB1, CYP1A1, EPHX1, PARK7, BAX, ADIPOQ, TLR9, XYLT2, SET, ATP7A, GABARAPL1, KIFAP3, GPER1, STX5, NUCB2, PLA2G16, AQP5, HSD17B7, DAD1, HSD11B2, CYP1B1, KSR1, OLFM1, HLA-DRA, SRD5A1, SGPP2, CREB3L1, PEMT |
| endoplasmic reticulum exit site | cellular_component | PDCD6 |
| endoplasmic reticulum lumen | cellular_component | WNT5A, COL4A2, STS, LIPC, FLT3, NTF4, PTGS2, COL18A1, SERPINA1, APOA1, BCHE, APOA2, PDGFA, CD4, WNT7A, THBS1, COL4A1, WNT1, COL5A2, GAS6, PLAUR, GHRL, WNT4, ARSH |
| endoplasmic reticulum membrane | cellular_component | BCL2, PLA2G4A, PTGDS, FOLR1, GJA1, CYP19A1, NOTCH1, UCHL1, CYP2A6, HLA-DRB1, STS, HMOX1, HSD3B2, PLA2G2A, CYP2B6, PTGS1, MTOR, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, HSD17B2, ALDH3A2, CYP17A1, EGFR, PGRMC1, CYP2E1, PTGES, CD4, CYP1A2, PDCD6, SGK1, TLR3, CYP26A1, HLA-DQA1, CD74, HLA-DPB1, CYP1A1, EPHX1, CDC42, RAC1, TYRO3, BAX, PLAUR, TLR9, XYLT2, FKBP4, FKBP5, GPER1, STX5, HSD17B7, DAD1, HSD11B2, CYP1B1, NOTCH4, KSR1, SFTPA1, HLA-DRA, SRD5A1, RHOA, SGPP2, CREB3L1, PEMT |
| endoplasmic reticulum Sec complex | cellular_component | CFTR |
| endoplasmic reticulum-Golgi intermediate compartment | cellular_component | HMGB1, FN1, PROM1, DICER1, NUCB2 |
| endoplasmic reticulum-Golgi intermediate compartment membrane | cellular_component | FOLR1, SERPINA1, STX5 |
| endosome | cellular_component | CDH1, CRHR1, FOLR1, IGF2R, HMGB1, GJA1, CFTR, SLC6A4, CDKN1B, ACE, CLCN3, KDR, FPR1, CCR5, HLA-DRB1, FLT1, STS, IL15, LHCGR, MRC1, CCR2, INSR, ITGB1, EGFR, ANXA1, NGF, PDCD6, FYN, CCDC22, TLR3, ANXA2, ASTN2, PTP4A3, HLA-DQA1, CD74, HLA-DPB1, TGFB2, NTRK2, CXCR4, TLR9, GPER1, GRB14, HLA-DRA, CD1A, RHOA |
| endosome lumen | cellular_component | PRLR |
| endosome membrane | cellular_component | SHC1, SLC6A4, HLA-DRB1, MRC1, INSR, EGFR, ANXA1, MAP3K7, TLR4, ERBB2, TLR3, TF, HLA-DQA1, HLA-DPB1, NTRK2, TLR9, GRB14, HLA-DRA, CD1A |
| endothelial microparticle | cellular_component | ANXA5, ENG |
| ER to Golgi transport vesicle | cellular_component | SERPINA1 |
| ER to Golgi transport vesicle membrane | cellular_component | FOLR1, HLA-DRB1, HLA-C, HLA-E, HLA-G, HLA-A, HLA-B, HLA-DQA1, CD74, HLA-DPB1, STX5, HLA-DRA |
| ESC/E(Z) complex | cellular_component | HDAC2, EZH2, SIRT1 |
| euchromatin | cellular_component | DNMT3A |
| eukaryotic 43S preinitiation complex | cellular_component | EIF3E |
| eukaryotic 48S preinitiation complex | cellular_component | EIF3E |
| eukaryotic translation initiation factor 3 complex | cellular_component | COPS5, EIF3E |
| excitatory synapse | cellular_component | ITGA3, FGFR2, SYP, NTRK2 |
| exocytic vesicle | cellular_component | IGF1 |
| external side of plasma membrane | cellular_component | ITGA6, CD40LG, ITGA3, CD36, KIT, ANXA5, ACE, CLCN3, FASLG, CCR1, CCR5, CXCR3, CD40, ENG, HLA-DRB1, IL6ST, ITGA2, CD79A, FAS, NCAM1, IL2RB, VCAM1, SELP, CTLA4, ITGB6, SDC1, FCER1G, IL13, CXCL12, ITGB1, ITGAV, IFNG, FGA, TNF, CXCL10, TLR4, CD4, THBS1, CTSB, ADA, IL2RA, ICAM1, CD74, IL4, IL6, FCER2, NRG1, IL1RL1, KLRD1, CD69, IL17A, MUC17, KLRK1, CCR7, CD83, LILRB1 |
| extracellular exosome | cellular_component | AKR1B1, H2AFX, CRK, HSPD1, PGM1, ATP5A1, AKR1D1, SRC, TXN, CDH1, CETP, PCNA, WNT5A, MME, ITGA3, PTGDS, PRDX6, FBLN1, MAPK1, FOLR1, IGF2R, LGALS3, IGFBP2, CLU, GJA1, CFTR, IGFBP3, BGN, CHI3L1, F3, GPX3, DPP6, VIM, MMP9, MIF, ANXA5, CTNNB1, HPGD, EPCAM, CFL1, SERPINF1, KRT19, TNFSF10, NME1, ACE, PLCD1, FASLG, SPP1, CSF1, SDC4, UCHL1, HSPA6, CD40, MUC1, AXL, ANXA4, COL4A2, S100P, IL6ST, ITGB5, TYK2, LGALS1, KRT7, ENO2, GSTP1, MMP7, C4A, SAA1, HLA-C, CD44, AZGP1, PECAM1, FAS, NCAM1, HLA-E, PLA2G2A, LIFR, VCAM1, TIMP2, STMN1, IL1RN, ITGB6, SDC1, EFNA1, COMT, LPO, PTGS1, ACP1, PON1, CD82, HLA-A, GSTT1, HSPA4, BSG, TIMP3, COL18A1, AQP2, AKR1C3, AFM, CXCL12, RARRES1, ALDH3A2, PRELP, FN1, ATP5B, INSR, ITGB3, ITGB1, CA2, HSP90AA1, MT-CO2, ITGAV, ANG, CRYAB, ACTN4, ANXA1, RHOC, SERPINA6, A2M, PGRMC1, SOD1, FGA, SERPINA1, PLAT, PRKCB, AHSG, APOA1, TIMP1, LTF, S100A6, APOA2, APOE, C3, LGALS9, HSPB1, ENO1, PDCD6, TPM3, CLDN5, CRP, WNT7A, SLPI, LAMA5, CAPN5, CLDN3, ANXA2, PROM1, SERPINE1, THBS1, KALRN, CTSB, SNCG, IL1B, CP, |
| extracellular matrix | cellular_component | MMP13, FBLN1, FGFR2, LGALS3, CLU, BGN, F3, MMP9, SERPINF1, WNT2, COL4A2, LAMA1, LGALS1, MMP7, MMP10, VCAN, MMP14, CMA1, MMP11, TNC, TIMP3, COL18A1, MMP12, PRELP, FN1, HSP90AA1, SOD1, PLAT, AHSG, TIMP1, APOE, CYR61, TGFB1I1, SLPI, LAMA5, ANXA2, SERPINE1, THBS1, KRT1, COL4A1, APCS, MMP1, CTSD, COL5A2, MMP2, MMP3, CTSG, TGFB2, RARRES2, IGFBP7, TPSAB1, LOXL1, POSTN, HTRA1, MMP24, DCN, LAMC1 |
| extracellular region | cellular_component | XDH, FGFR1, TXN, CDH1, INHBA, FGF2, VEGFA, MET, CETP, BMP4, CD40LG, F2R, WNT5A, PTGDS, TNFRSF1A, MMP13, CCL5, FBLN1, FOLR1, FGFR2, HMGB1, LGALS3, IGFBP2, CLU, IGFBP3, BGN, CHI3L1, F3, GPX3, IL10, IL12B, LEP, MMP9, CXCL8, MIF, CCL3, SERPINF1, CASP1, WNT2, MBL2, TNFSF10, ERBB3, NOTCH1, ACE, KDR, FASLG, SPP1, CSF1, SDC4, FLT4, TNFRSF1B, CD40, MUC1, AGTR2, PRLR, COL4A2, FST, IGFBP5, IL6R, IL6ST, CRHBP, LAMA1, SPARC, LGALS1, HGF, FLT1, IGFBP1, CNTF, MMP7, MMP10, CXCL1, PAEP, IL1R1, C4A, CFC1B, SAA1, KITLG, LIPC, AZGP1, FAS, LEPR, CCL2, NCAM1, VCAN, PLA2G2A, IL15, LIF, LIFR, IL9, TIMP2, IL1RN, IL1R2, SDC1, CXCL2, IL11, EFNA1, PTN, MDK, BMP6, LPO, IGFBP4, BDNF, CMA1, MMP11, TNC, PTX3, PON1, IL12A, NTF4, IL13, ADM, TIMP3, VEGFC, COL18A1, MMP12, CXCL5, PTGFR, AFM, NPTX2, CXCL12, PRELP, FN1, IGF1, GREM1, HSP90AA1, EGFR, FGF1, ANG, IFNG, TGFB1, ACTN4, ANXA1, SERPINA6, A2M, SOD1, FGA, SERPINA1, PLAT, INHA, FSTL3, IL1A, AHSG, NGF, APOA1, TIMP1, LTF, BCHE, APOA2, APOE, TNF, CXCL10, PDGFA, C3, LGALS9, CCL25, TNFRSF11B, CCL2 |
| extracellular space | cellular_component | XDH, AKR1B1, HSPD1, INHBA, FGF2, VEGFA, CETP, BMP4, CD40LG, WNT5A, PTGDS, TNFRSF1A, MMP13, PRDX6, CCL5, FBLN1, IGF2R, HMGB1, LGALS3, IGFBP2, CLU, IGFBP3, CD36, CHI3L1, F3, GPX3, IL10, KIT, IL12B, LEP, MMP9, CXCL8, MIF, ANXA5, CFL1, CCL3, SERPINF1, WNT2, MBL2, TNFSF10, ERBB3, ACE, FASLG, SPP1, CSF1, CD40, MUC1, AXL, ENG, IL6R, IL6ST, CRHBP, LAMA1, SPARC, LGALS1, HGF, FLT1, IGFBP1, CNTF, ENO2, GSTP1, MMP7, MMP10, CXCL1, HMOX1, IL1R1, C4A, SAA1, KITLG, LIPC, AZGP1, PECAM1, FAS, TDGF1, CCL2, VCAN, PLA2G2A, IL15, LIF, IL9, VCAM1, TIMP2, SELP, SELE, IL1RN, CXCL2, IL11, PTN, BMP6, LPO, IGFBP4, TNC, PTX3, PON1, IL12A, IL13, ADM, TIMP3, VEGFC, COL18A1, CXCL5, AFM, CXCL12, PRELP, FN1, IGF1, GREM1, CA2, EGFR, FGF1, ANG, IFNG, TGFB1, ACTN4, ANXA1, SERPINA6, A2M, SOD1, FGA, SERPINA1, PLAT, INHA, FSTL3, IL1A, AHSG, APOA1, TIMP1, LTF, BCHE, APOA2, APOE, TNF, CXCL10, PDGFA, C3, LGALS9, HSPB1, ENO1, CCL25, TNFRSF11B, CCL21, CRP, CCL22, WNT7A, NRP1, MSTN, ANGPT2, SLPI, LAMA5, DEFB4A, CCL16, ANXA2, PROM1, SERPINE1, THBS1, FIGF, |
| extracellular vesicle | cellular_component | PRELP, FGA, APOA1, APOE, ITGB2 |
| extrinsic component of cytoplasmic side of plasma membrane | cellular_component | SRC, ALOX15, JAK1, TYK2, S100A6, FYN, KRAS, PTK2, ERRFI1, RHOA |
| extrinsic component of endoplasmic reticulum membrane | cellular_component | ALDH3A2 |
| extrinsic component of endosome membrane | cellular_component | ANXA1 |
| extrinsic component of external side of plasma membrane | cellular_component | ANXA1, TF |
| extrinsic component of membrane | cellular_component | ANXA1, BCL2L11, PLAUR, MUC16 |
| extrinsic component of plasma membrane | cellular_component | TDGF1, ENO1, ANXA2, RAC1, STOML2 |
| fascia adherens | cellular_component | GJA1, CTNNB1 |
| Fc-epsilon receptor I complex | cellular_component | FCER1G |
| female pronucleus | cellular_component | TET3 |
| fibrinogen complex | cellular_component | FBLN1, FN1, FGA, THBS1 |
| filamentous actin | cellular_component | PAK1 |
| filopodium | cellular_component | VCAM1, ITGB1, CDC42 |
| filopodium membrane | cellular_component | ITGA3, ITGB3, ITGAV |
| flotillin complex | cellular_component | CDH1, CTNNB1, CTNNA1 |
| focal adhesion | cellular_component | CDH1, ITGA6, MME, ITGA3, MAPK1, IGF2R, GJA1, VIM, OPRM1, ANXA5, CTNNB1, CFL1, HMGA1, SDC4, CTNNA1, ENG, JAK1, ITGA2, ITGB5, FLT1, CD44, MMP14, SDC1, TNC, L1CAM, BSG, ITGB3, ITGB1, EGFR, ITGAV, ACTN4, ANXA1, HSPB1, NRP1, TGFB1I1, CAPN5, PAK4, PLAU, KRAS, ICAM1, CAT, CDC42, RAC1, PTK2, PLAUR, ACTB, TEK, PAK1, ADAM17, LIMK1, RND3, RHOA |
| gamma-tubulin ring complex | cellular_component | BRCA1 |
| gap junction | cellular_component | GJA1 |
| germinal vesicle | cellular_component | AURKA |
| glutamate-cysteine ligase complex | cellular_component | GCLC |
| Golgi apparatus | cellular_component | MSH6, CDH1, PLA2G4A, F2R, PTGDS, PPARG, TNFRSF1A, MMP13, MAPK1, FGFR2, CLU, GJA1, CD36, OPRM1, NOTCH1, CLCN3, KDR, ID1, CTNNA1, STIP1, HLA-DRB1, CRHBP, STS, HLA-C, CD44, IL15, VCAM1, CTLA4, PTGS1, NOS3, MTOR, HLA-A, AQP2, CHEK2, ESR1, EGFR, CRYAB, LGR5, SERPINA1, FSTL3, APOE, TLR2, CXCL14, PAK4, NRAS, HLA-B, HLA-DQA1, CAT, CD74, HLA-DPB1, GALT, PAK1, F2RL1, XYLT2, ATP7A, GABARAPL1, KIFAP3, LIMK1, GPER1, STX5, PCSK5, PAX2, NUCB2, RND3, CEP85, P2RX3, CRHR2, POSTN, MANEA, PTGES2, GBGT1, CHST6, CHST2, MMP24, NPY, HLA-DRA, SMPD3 |
| Golgi cis cisterna | cellular_component | SMPD3 |
| Golgi lumen | cellular_component | WNT5A, BGN, SDC4, MUC1, VCAN, MMP14, SDC1, MMP11, PRELP, TGFB1, NGF, WNT7A, DEFB4A, CGA, LHB, WNT1, GAS6, PCSK5, WNT4, DEFB1, MUC16, MUC17, MUC4, DCN |
| Golgi membrane | cellular_component | TNFRSF1A, FOLR1, GJA1, NOTCH1, CLCN3, HLA-DRB1, HLA-C, NCAM1, HLA-E, HLA-G, NOS3, MTOR, HLA-A, BSG, EGFR, CYP2E1, SERPINA1, PDGFA, TLR3, NRAS, HLA-B, HLA-DQA1, CD74, HLA-DPB1, CDC42, RAC1, TLR9, XYLT2, GPER1, STX5, RND3, MANEA, PTGES2, NOTCH4, GBGT1, CHST6, CHST2, HLA-DRA, SMPD3 |
| Golgi-associated vesicle membrane | cellular_component | GJA1, CFTR |
| granulocyte macrophage colony-stimulating factor receptor complex | cellular_component | CSF2RB |
| growth cone | cellular_component | GSK3B, ITGA3, CLU, TIMP2, L1CAM, ANG, NRP1, DICER1, NTRK2, DPYSL2 |
| growth cone membrane | cellular_component | NECTIN1 |
| haptoglobin-hemoglobin complex | cellular_component | HP |
| hemidesmosome | cellular_component | ITGA6, ITGB1 |
| heterochromatin | cellular_component | DNMT1, SUV39H1, DNMT3A, CHD5, MBD2 |
| HFE-transferrin receptor complex | cellular_component | BMPR1B, TF |
| high-density lipoprotein particle | cellular_component | CETP, SAA1, LIPC, PON1, APOA1, APOA2, APOE |
| histone acetyltransferase complex | cellular_component | KAT2B |
| histone deacetylase complex | cellular_component | HDAC1, MBD2 |
| histone pre-mRNA 3'end processing complex | cellular_component | YBX1 |
| host cell surface | cellular_component | AXL |
| I band | cellular_component | CRYAB, KAT2B |
| I-kappaB/NF-kappaB complex | cellular_component | NFKB1, RELA |
| IkappaB kinase complex | cellular_component | MAP3K7 |
| immunological synapse | cellular_component | LGALS3, ICAM1, STOML2 |
| inhibin A complex | cellular_component | INHBA, INHA |
| inhibin B complex | cellular_component | INHA |
| inhibin-betaglycan-ActRII complex | cellular_component | INHA |
| insulin receptor complex | cellular_component | INSR |
| insulin-like growth factor binding protein complex | cellular_component | IGFBP3, IGFBP5, IGF1 |
| insulin-like growth factor ternary complex | cellular_component | IGFBP3, IGFBP5, IGF1 |
| integral component of lumenal side of endoplasmic reticulum membrane | cellular_component | HLA-DRB1, HLA-C, HLA-E, HLA-G, HLA-A, HLA-B, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
| integral component of membrane | cellular_component | BCL2, FGFR1, CDH1, ITGA6, FSHR, MET, CRHR1, CD40LG, F2R, MME, ITGA3, TNFRSF1A, FGFR2, IGF2R, GJA1, CFTR, CD36, F3, DPP6, KIT, OPRM1, EPCAM, PTGER4, SLC6A4, TNFSF10, ERBB3, NOTCH1, ACE, DRD2, CLCN3, KDR, FPR1, FASLG, CSF1, SDC4, CCR1, CCR5, FLT4, CXCR3, CSF2RB, TNFRSF1B, CD40, MUC1, PDGFRA, AXL, AGTR1, AGTR2, ENG, PRLR, HLA-DRB1, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, FLT1, STS, IL1R1, CXCR1, CXCR2, HLA-C, CD44, KITLG, CD79A, PECAM1, FAS, LEPR, NCAM1, HLA-E, KLRC1, HSD3B2, IL2RB, LIFR, VCAM1, MMP14, SELP, CTLA4, SELE, HLA-G, IL1R2, ITGB6, SDC1, TACR2, TACR1, MAOA, COMT, CDH3, LHCGR, MRC1, SLC6A2, CD82, FLT3, KIR2DL1, KIR2DL3, FCER1G, HLA-A, OXTR, SSTR1, SRD5A2, L1CAM, SSTR5, BSG, HSD17B2, AQP2, CCR2, PTGFR, PTGER3, PTGER2, KIR3DL1, KIR2DS4, RARRES1, ALDH3A2, CCR9, ESR1, INSR, ITGB3, ITGB1, EGFR, MT-CO2, ITGAV, LGR5, PGRMC1, IGF1R, TNF, PTGES, TLR2, TLR4, ERBB2, CD4, SLC22A23, BMPR1B, CLDN5, CXCR6, CLDN4, NRP1, PCDH17, PGRMC2, ABCC4, TLR3, CLDN3, PROM1, NRP2, ASTN2, TNFRSF21, NCR1, AQP8, CLDN7, ITGB2, EGF, IL2RA, HL |
| integral component of nuclear inner membrane | cellular_component | P2RX3 |
| integral component of plasma membrane | cellular_component | FGFR1, FSHR, MET, CRHR1, CD40LG, F2R, MME, TNFRSF1A, FOLR1, FGFR2, IGF2R, GJA1, CD36, OPRM1, EPCAM, SLC6A4, TNFSF10, ERBB3, DRD2, KDR, FASLG, SDC4, CCR1, CCR5, FLT4, CXCR3, CSF2RB, TNFRSF1B, CD40, MUC1, PDGFRA, AXL, AGTR1, AGTR2, EDNRA, FLT1, IL1R1, CXCR2, CD44, CD79A, FAS, KLRC1, IL2RB, IL15, LIFR, MMP14, SELP, CTLA4, SDC1, TACR2, TACR1, EFNA1, LHCGR, MRC1, SLC6A2, CD82, FLT3, KIR2DL1, KIR2DL3, FCER1G, HLA-A, OXTR, SSTR1, SSTR5, BSG, AQP2, CCR2, PTGFR, PTGER3, PTGER2, KIR3DL1, KIR2DS4, CCR9, INSR, ITGB3, ITGAV, LGR5, IGF1R, TNF, TLR2, TLR4, SLC22A23, BMPR1B, TNFRSF11B, CXCR6, CLDN4, TLR3, CLDN3, PROM1, TNFRSF21, NCR1, AQP8, HLA-B, HLA-DQA1, ICAM1, FCER2, CSF1R, NRG1, NTRK2, ATP1B4, TYRO3, PLAUR, TEK, F2RL1, ATP7A, NECTIN1, MST1R, ADAM17, AGER, GPER1, NECTIN3, ADAM8, CADM1, SCARB1, AMHR2, SLC26A8, TRPV1, JAG1, MICA, AQP5, P2RX3, KISS1R, FOLH1, CD69, TRO, CRHR2, IL11RA, KIR2DS5, NECTIN4, NOTCH4, CADM2, SLCO2A1, SLCO4A1, MUC4, IL1RAP, LPAR3, MMP24, HLA-DRA, CD1A, KLRK1, CCR8, CD83, KIR3DS1 |
| integral component of synaptic vesicle membrane | cellular_component | SYP |
| integrin alpha1-beta1 complex | cellular_component | ITGB1 |
| integrin alpha10-beta1 complex | cellular_component | ITGB1 |
| integrin alpha11-beta1 complex | cellular_component | ITGB1 |
| integrin alpha2-beta1 complex | cellular_component | ITGA2, ITGB1 |
| integrin alpha3-beta1 complex | cellular_component | ITGA3, ITGB1 |
| integrin alpha7-beta1 complex | cellular_component | ITGB1 |
| integrin alpha8-beta1 complex | cellular_component | ITGB1 |
| integrin alpha9-beta1 complex | cellular_component | ITGB1 |
| integrin alphaL-beta2 complex | cellular_component | ITGB2 |
| integrin alphav-beta3 complex | cellular_component | ITGB3, ITGAV |
| integrin alphav-beta5 complex | cellular_component | ITGB5, ITGAV |
| integrin alphav-beta8 complex | cellular_component | ITGAV |
| integrin complex | cellular_component | ITGA6, ITGA3, ITGA2, ITGB5, ITGB6, ITGB3, ITGB1, ITGAV, ITGB2 |
| intercalated disc | cellular_component | GJA1, ANXA5, CTNNB1, CTNNA1, ITGB1, PAK1, YWHAH |
| intercellular bridge | cellular_component | SRA1 |
| intercellular canaliculus | cellular_component | MMP13 |
| interleukin-12 complex | cellular_component | IL12B, IL12A |
| interleukin-23 complex | cellular_component | IL12B, IL23A |
| interleukin-28 receptor complex | cellular_component | IL10RB |
| interleukin-6 receptor complex | cellular_component | IL6R, IL6ST, IL6 |
| intermediate filament | cellular_component | GJA1, VIM, KRT19, NME1, KRT7, KRT1 |
| intermediate filament cytoskeleton | cellular_component | VIM, PSMD10 |
| intermediate-density lipoprotein particle | cellular_component | APOE |
| interphase microtubule organizing center | cellular_component | BIRC5 |
| interstitial matrix | cellular_component | TNC, IGF1, SMOC2 |
| intracellular | cellular_component | BCL2, CCND1, NOS2, CD40LG, CLU, BGN, APEX1, CXCL8, ANXA5, CFL1, CCL3, ERBB3, DRD2, CXCR3, UCHL1, CSF2RB, AXL, AGTR1, PRLR, IGFBP5, CRHBP, SPARC, LGALS1, ENO2, GSTP1, CXCL1, CXCR2, IL2RB, STMN1, IL1RN, PIK3CA, OXTR, AKR1C3, HSP90AA1, EGFR, ITGAV, IFNG, ACTN4, TNF, LGALS9, HSPB1, SMAD7, CCL21, TGFB1I1, TLR3, CAPN5, CTSB, DIRAS3, PNP, PRL, GHRH, IL2RA, CSF2, CD74, IL5, CSF1R, SMAD3, BCL2L1, NTRK2, GAS6, BAX, SMAD2, CCL19, GABARAPL1, FOXP3, SMAD4, GPER1, TRIM36, TRPV1, KISS1R, ANGPT1, IL16, FSD1, CCR7, CCL11 |
| intracellular membrane-bounded organelle | cellular_component | MSH6, PLA2G4A, PPARG, FGFR2, CLU, CD40, BRAF, CYP2A6, CTNNA1, COL4A2, STS, HMOX1, VCAN, CYP2B6, PTGS1, CMA1, PON1, MTOR, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, ALDH3A2, INSR, CYP17A1, CLOCK, PGRMC1, CYP2E1, IGF1R, PTGES, CYP1A2, FYN, CYP26A1, PROM1, BCL2L11, CTSB, CAT, CYP1A1, EPHX1, YBX1, HPSE, NECTIN1, DNMT3B, SCARB1, USF2, KISS1R, HSD11B2, GRB14, CYP1B1, SRD5A1 |
| intracellular ribonucleoprotein complex | cellular_component | GSK3B, BRCA1, TIA1, ACTN4, TERT, YBX1, ACTB, RPL41, SRA1 |
| intraciliary transport particle | cellular_component | KIFAP3 |
| intrinsic component of endoplasmic reticulum membrane | cellular_component | CYP2E1 |
| intrinsic component of external side of plasma membrane | cellular_component | F3 |
| intrinsic component of Golgi membrane | cellular_component | CHST2 |
| intrinsic component of plasma membrane | cellular_component | CRHR1, PDGFRA, TLR2, TLR4, TNFRSF21, TRPV1, ADIPOR2, ADIPOR1 |
| invadopodium | cellular_component | PAK1 |
| invadopodium membrane | cellular_component | ITGA3, ITGB1, PLAUR |
| IPAF inflammasome complex | cellular_component | CASP1 |
| keratin filament | cellular_component | KRT7, KRT1, GPER1 |
| kinesin complex | cellular_component | KIFAP3 |
| kinesin II complex | cellular_component | KIFAP3 |
| kinetochore | cellular_component | BIRC5, PLK1, KAT2B |
| lamellar body | cellular_component | SFTPA1 |
| lamellipodium | cellular_component | CDH1, CTNNB1, CTNNA1, PIK3CA, ITGB1, RAC1, PTK2, AIF1, RHOA |
| lamellipodium membrane | cellular_component | CFL1, ITGB3, ITGAV |
| laminin-1 complex | cellular_component | LAMA1, LAMC1 |
| laminin-10 complex | cellular_component | LAMA5, LAMC1 |
| laminin-11 complex | cellular_component | LAMA5, LAMC1 |
| laminin-2 complex | cellular_component | LAMC2 |
| laminin-3 complex | cellular_component | LAMA1 |
| laminin-5 complex | cellular_component | LAMA5 |
| late endosome | cellular_component | SRC, F2R, MAPK1, IGF2R, GJA1, CLCN3, LIPC, TF, CD74, CXCR4, ATP7A |
| late endosome membrane | cellular_component | CLCN3, HLA-DRB1, ANXA2, HLA-DRA |
| lateral plasma membrane | cellular_component | CDH1, GJA1, CTNNB1, EPCAM, ERBB3, DRD2, ANXA1, CLDN4, CLDN3, CLDN7 |
| leading edge membrane | cellular_component | CDC42 |
| Lewy body | cellular_component | GPX1 |
| lipid particle | cellular_component | ALOX15, G0S2, ANXA2 |
| lipopolysaccharide receptor complex | cellular_component | HSPD1, TLR4 |
| low-density lipoprotein particle | cellular_component | APOE |
| lysosomal lumen | cellular_component | BGN, FASLG, SDC4, VCAN, SDC1, PRELP, HSP90AA1, GC, CD74, CTSD, PSAP, HPSE, NAGLU, DCN |
| lysosomal membrane | cellular_component | IGF2R, CFTR, HLA-DRB1, MTOR, TLR3, ANXA2, CP, EGF, HLA-DQA1, CD74, HLA-DPB1, PSAP, HPSE, SCARB1, HLA-DRA |
| lysosome | cellular_component | SRC, MMP13, PRDX6, IGF2R, GJA1, ACE, FASLG, HLA-DRB1, STS, MTOR, SOD1, CTSB, IL1B, ADA, HLA-DQA1, CAT, CD74, HLA-DPB1, CTSD, MPO, PSAP, HPSE, CXCR4, TLR9, PAX2, NAGLU, HLA-DRA |
| M band | cellular_component | ENO1 |
| macromolecular complex | cellular_component | MTOR |
| macrophage migration inhibitory factor receptor complex | cellular_component | CD44, CD74 |
| macropinosome | cellular_component | MMP14, ANXA2 |
| male germ cell nucleus | cellular_component | H2AFX, MLH1 |
| male pronucleus | cellular_component | TET3 |
| MAML1-RBP-Jkappa- ICN1 complex | cellular_component | NOTCH1 |
| mast cell granule | cellular_component | AKR1B1, KIT, GATA2, CXCR2, ANXA1, S100A13 |
| meiotic spindle | cellular_component | AURKA |
| melanosome | cellular_component | SERPINF1, MMP14, BSG, ITGB3, ITGB1, HSP90AA1, ANXA2, CTSB, CTSD, RAC1 |
| membrane | cellular_component | GSK3B, MSH2, MLH1, CRK, BCL2, HSPD1, NDUFS1, ATP5A1, FGFR1, SRC, CDH1, ITGA6, YAP1, CCND1, VEGFA, FSHR, MET, CRHR1, CD40LG, F2R, MME, ITGA3, PTGDS, TNFRSF1A, PRDX6, FOLR1, FGFR2, IGF2R, HMGB1, LGALS3, CLU, GJA1, CFTR, PIK3R1, CD36, ALOX15, F3, DPP6, KIT, CYP19A1, IL12B, OPRM1, ANXA5, AKT1, CTNNB1, CCNB1, ATF2, EPCAM, CFL1, PTGER4, SLC6A4, TNFSF10, ERBB3, NOTCH1, NME1, ACE, DRD2, CLCN3, KDR, FPR1, FASLG, CSF1, SDC4, CCR1, CCR5, FLT4, CXCR3, UCHL1, CSF2RB, TNFRSF1B, CD40, BRAF, CYP2A6, MUC1, CTNNA1, PDGFRA, AXL, AGTR1, AGTR2, ENG, PRLR, HLA-DRB1, S100P, JAK1, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, TYK2, HGF, FLT1, STS, ENO2, HMOX1, IL1R1, CXCR1, CXCR2, HLA-C, CD44, KITLG, CD79A, PECAM1, FAS, LEPR, TDGF1, NCAM1, VCAN, HLA-E, KLRC1, HSD3B2, PLA2G2A, IL2RB, IL15, LIFR, VCAM1, MMP14, SELP, CTLA4, SELE, STMN1, HLA-G, IL1R2, ITGB6, SDC1, TACR2, TACR1, CYP2B6, EFNA1, PTN, MAOA, COMT, CDH3, LHCGR, MRC1, PTGS1, SLC6A2, TNC, CD82, FLT3, KIR2DL1, KIR2DL3, NOS3, MTOR, FCER1G, HLA-A, HMOX2, OXTR, SSTR1, SRD5A2, L1CAM, CYP2C19, S |
| membrane attack complex | cellular_component | C5 |
| membrane raft | cellular_component | GSK3B, TNFRSF1A, GJA1, CD36, OPRM1, SLC6A4, KDR, CASP3, FASLG, SDC4, TNFRSF1B, EDNRA, CD79A, PECAM1, FAS, TDGF1, SELE, STAT6, BSG, ITGB1, EGFR, TNF, TLR2, CD4, FYN, ANXA2, KRAS, ICAM1, CTSD, PARK7, HPSE, TEK, STOML2, ADAM17, P2RX3, ANGPT1, CD1A |
| membrane-bounded organelle | cellular_component | GSK3B |
| methionine adenosyltransferase complex | cellular_component | MAT2A |
| MHC class I protein complex | cellular_component | HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, HLA-B |
| MHC class Ib protein complex | cellular_component | HLA-E |
| MHC class II protein complex | cellular_component | HLA-DRB1, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
| microtubule | cellular_component | CRHBP, MAP2, STMN1, AURKA, BIRC5, BCL2L11, SPRY2, DPYSL2, FKBP4, GABARAPL1, Sep-09, FSD1 |
| microtubule associated complex | cellular_component | MAP2 |
| microtubule cytoskeleton | cellular_component | MAPK1, AKT1, AURKA, CRYAB, PLK1, KIFAP3, PMS2, SRA1 |
| microtubule organizing center | cellular_component | MAPK1, CTNNB1, CCNB1, BRCA2, AURKA, LATS1, NR3C1, SNCG, CDC42, PLK1, PTK2, BCL2L1, PAX2, CEP85, FSD1 |
| microvillus | cellular_component | LIPC, VCAM1, OXTR, CA2, TGFB1, PDGFA, TEK, AQP5, ANGPT1, MUC17 |
| microvillus membrane | cellular_component | CTNNB1, S100P, ITGB3, ITGAV, PROM1, SCARB1 |
| midbody | cellular_component | AURKA, BIRC5, ANXA2, CDC42, PLK1, RHOA |
| mismatch repair complex | cellular_component | MSH2, PMS2 |
| mitochondrial crista | cellular_component | STAR |
| mitochondrial inner membrane | cellular_component | HSPD1, NDUFS1, ATP5A1, SRC, STAT3, PLA2G4A, LGALS3, HSD3B2, ALDH3A2, ATP5B, MT-CO2, CYP11A1, BCL2L1, STOML2, ATAD3A, CYP24A1 |
| mitochondrial intermembrane space | cellular_component | NDUFS1, HSD3B2, STAR, SOD1, CAT, PARK7, STOML2 |
| mitochondrial matrix | cellular_component | HSPD1, NDUFS1, ATP5A1, SHC1, BRCA1, ATP5B, CYP11A1, SOD1, TP53, NR3C1, GPX1, C1QBP, ARG2, BCL2L1, PARK7, MCL1 |
| mitochondrial membrane | cellular_component | BCL2, CLU, HSD3B2, ATP5B, ANXA1, CYP11A1, BCL2L1, BAX, GPER1, ABCG2, PEMT |
| mitochondrial nucleoid | cellular_component | ATP5B, TERT, ATAD3A |
| mitochondrial outer membrane | cellular_component | BCL2, GJA1, ATF2, NME1, MAOA, MTOR, BCL2L11, PGR, BCL2L1, BAX, MCL1 |
| mitochondrial permeability transition pore complex | cellular_component | BAX |
| mitochondrial proton-transporting ATP synthase complex | cellular_component | ATP5A1, ATP5B |
| mitochondrial proton-transporting ATP synthase, catalytic core | cellular_component | ATP5B |
| mitochondrial respiratory chain complex I | cellular_component | NDUFS1, PARK7 |
| mitochondrion | cellular_component | GSK3B, BCL2, HSPD1, NDUFS1, ATP5A1, SRC, TXN, STAT3, TNFRSF1A, MAPK1, CLU, GJA1, APEX1, AKT1, SHC1, ATF2, NFKB1, CASP1, NME1, BRAF, SPARC, GSTP1, G0S2, HSD3B2, MAOA, COMT, MTOR, BSG, STAR, ALDH3A2, XRCC3, GSTZ1, ATP5B, ESR1, CYP17A1, MT-CO2, CRYAB, CYP2E1, CYP11A1, SOD1, TP53, TERT, FYN, SGK1, NR3C1, BCL2L11, CTSB, PGR, AGR2, GPX1, KRAS, CAT, CYP1A1, MPO, PSAP, MMP2, C1QBP, PTEN, ARG2, BCL2L1, PARK7, FOXO1, DPYSL2, BAX, STOML2, FKBP4, ESR2, MCL1, GABARAPL1, SIRT1, YWHAH, GPER1, CDKN2A, TP63, ABCG2, NUDT6, CYP1B1, OLFM4, PTGES2, ATAD3A, OGG1, FHIT, CYP24A1, PEMT |
| mitotic spindle | cellular_component | MAPK1, AURKA, CDC42 |
| MLL5-L complex | cellular_component | ACTB |
| motile cilium | cellular_component | ANXA1, HIF1A |
| multivesicular body | cellular_component | GJA1, CRHBP, CD79A, CD74 |
| multivesicular body, internal vesicle lumen | cellular_component | EGFR |
| muscle thin filament tropomyosin | cellular_component | TPM3 |
| MutLalpha complex | cellular_component | MLH1, PMS2 |
| MutSalpha complex | cellular_component | MSH2, MSH6 |
| MutSbeta complex | cellular_component | MSH2 |
| myelin sheath | cellular_component | BCL2, NDUFS1, ATP5A1, MIF, NME1, UCHL1, STIP1, ENO2, ATP5B, CA2, HSP90AA1, CRYAB, SOD1, ENO1, ERBB2, CDC42, DPYSL2, PLCB1, SRD5A1 |
| myelin sheath abaxonal region | cellular_component | ITGB1 |
| myelin sheath adaxonal region | cellular_component | ANXA2, PTEN |
| myofibril | cellular_component | CALD1 |
| NatA complex | cellular_component | NAA15 |
| nBAF complex | cellular_component | ARID1A |
| neurofibrillary tangle | cellular_component | CLU |
| neurofilament | cellular_component | NRP1 |
| neuromuscular junction | cellular_component | F2R, PTN, ITGB1, NRG1, POSTN |
| neuron projection | cellular_component | SRC, HMGB1, CLU, VIM, OPRM1, CTNNB1, MTHFR, SLC6A4, NFKB1, BRAF, MAP2, FAS, TIMP2, STMN1, SLC6A2, SSTR1, SSTR5, PTGS2, PTGER3, STAR, ESR1, HSP90AA1, ACTN4, SOD1, SGK1, FOS, SYP, CDC42, PTEN, PARK7, DPYSL2, FKBP4, ESR2, ATP7A, NECTIN1, LIMK1, TP63, P2RX3, KISS1 |
| neuron projection terminus | cellular_component | MME, PTGER4, UCHL1, FSTL3, SYP |
| neuronal cell body | cellular_component | GSK3B, DNMT1, DPP6, ANXA5, PTGER4, SERPINF1, UCHL1, TNFRSF1B, IL6ST, ENO2, FAS, CCL2, TIMP2, MTOR, SRD5A2, CCR2, PTGER3, STAR, IGF1, HSP90AA1, CYP17A1, ANG, TGFB1, SOD1, INHA, APOE, BMPR1B, NRP1, SNCG, ADA, CRH, CDC42, TGFB2, NTRK2, DPYSL2, FKBP4, ESR2, ATP7A, AGER, UCN, P2RX3, SST, CRHR2, KISS1, OLFM1, TBX21, SRD5A1 |
| NF-kappaB complex | cellular_component | RELA |
| NLRP1 inflammasome complex | cellular_component | CASP1 |
| NLRP3 inflammasome complex | cellular_component | CASP1 |
| nonhomologous end joining complex | cellular_component | XRCC4 |
| NOS2-CD74 complex | cellular_component | CD74 |
| npBAF complex | cellular_component | ARID1A |
| NuA4 histone acetyltransferase complex | cellular_component | ACTB |
| nuclear aryl hydrocarbon receptor complex | cellular_component | AHR, AHRR |
| nuclear body | cellular_component | TP53, CDKN2A |
| nuclear chromatin | cellular_component | MSH6, H2AFX, GATA3, STAT3, AR, MUC1, STAT6, ESR1, JUN, TP53, ARID1A, RUNX3, HDAC2, SMAD3, PLCB1, ACTB, SMAD2, KAT2B, HDAC1, EZH2, SIRT1, SMAD4, EHMT2, TP63, DLX5, MBD2 |
| nuclear chromosome | cellular_component | MSH6, HMGA2, JUN, BIRC5 |
| nuclear chromosome, telomeric region | cellular_component | MSH2, PCNA, APEX1, BRCA2, XRCC3, TERT, ATM |
| nuclear envelope | cellular_component | STS, PTGS1, PTGER3, S100A6, NRM, ATP1B4, TYRO3, BAX, SIRT1, GPER1, CSE1L, NUCB2 |
| nuclear envelope lumen | cellular_component | IGF2R, BCHE, PTGES |
| nuclear euchromatin | cellular_component | CTNNB1, JUN, SIRT1 |
| nuclear heterochromatin | cellular_component | DNMT3A, SIRT1 |
| nuclear inner membrane | cellular_component | NRM, SMAD3, ATP1B4, SIRT1 |
| nuclear lamina | cellular_component | SUV39H1 |
| nuclear matrix | cellular_component | CFL1, SPARC, TP53, TGFB1I1, DNMT3A, OGG1 |
| nuclear membrane | cellular_component | BCL2, PTGDS, PTGER4, ANXA4, EDNRA, HSD17B1, PTGER3, EGFR, PDCD6, YBX1, BCL2L1, PLCB1, PAK1, IPO13 |
| nuclear nucleosome | cellular_component | HIST3H3 |
| nuclear replication fork | cellular_component | PCNA |
| nuclear speck | cellular_component | APEX1, WT1, HIF1A, PLCB1, OGG1, PIAS3 |
| nuclear stress granule | cellular_component | TIA1 |
| nuclear telomere cap complex | cellular_component | TERT |
| nuclear transcription factor complex | cellular_component | CTNNB1, SOX15 |
| nucleolus | cellular_component | GATA3, APEX1, HMOX1, MAP2, WT1, MKI67, FGF1, ANG, PGRMC1, TP53, TERT, MYC, SMAD7, CTSB, C1QBP, PLK1, SIRT1, CDKN2A, PAX2, CEP85, PAFAH1B2, ISG20, NANOG, IL37 |
| nucleoplasm | cellular_component | MSH2, MSH6, AKR1B1, H2AFX, MLH1, EGR1, TXN, GATA3, YAP1, CCND1, BCL6, STAT3, DNMT1, PCNA, HMGA2, PPARG, MAPK1, FGFR2, HMGB1, APEX1, MIF, AKT1, CTNNB1, CCNB1, ATF2, HPGD, BRCA1, NFKB1, HMGA1, AR, AHR, CDKN1B, NOTCH1, ID1, CASP3, UCHL1, CDKN1A, VDR, XRCC1, ENG, BRCA2, GATA2, TIA1, RBP1, USF1, HSD17B1, HOXB2, IL15, SELP, STAT6, WT1, HNF1B, ARNT, MTOR, SOX2, ZEB1, CHEK2, PSMD9, XRCC3, AURKA, ESR1, HSP90AA1, JUN, FGF1, CRYAB, CLOCK, ANXA1, SOD1, PRKCB, FSTL3, TP53, SUV39H1, TERT, MYC, BIRC5, SGK1, SMAD7, NR5A2, RB1, ARID1A, FOS, NR3C1, KHDRBS3, PRDM1, PSMD10, PGR, PRM1, XRCC4, COPS5, PTEN, PLK1, YBX1, HDAC2, SMAD3, RELA, DNMT3A, EIF3E, HPSE, HIF1A, FOXP1, HES5, FOXO1, ACTB, NR5A1, HSF1, EIF4EBP1, SMAD2, HEY1, ACLY, FKBP4, ESR2, MCL1, PPARA, SET, NFKB2, POU5F1, KAT2B, HDAC1, ELAVL1, FKBP5, EZH2, SIRT1, ID2, ATM, STAT4, SMAD4, LIMK1, EHMT2, HIST3H3, STX5, DNMT3B, HIST2H3A, NR0B2, CDKN2A, CSE1L, TP63, GATA6, SUV39H2, USF2, PMS2, PLCB3, KLF9, PPRC1, NOTCH4, ISG20, NANOG, GATA5, VEZT, OGG1, CYP24A1, SRA1, MBD2, PIAS3 |
| nucleosome | cellular_component | H2AFX, PRM1, HIST3H3, HIST2H3A |
| nucleus | cellular_component | GSK3B, MSH2, MSH6, H2AFX, MLH1, CRK, BCL2, FGFR1, EGR1, SRC, TXN, GATA3, YAP1, FGF2, CCND1, BCL6, STAT3, NOS2, NR2F2, DNMT1, PCNA, CDX1, PLA2G4A, HMGA2, PTGDS, PPARG, MAPK1, FOLR1, FGFR2, IGF2R, HMGB1, LGALS3, CLU, IGFBP3, APEX1, PIK3R1, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, ATF2, CFL1, BRCA1, NFKB1, HMGA1, AR, TOB1, AHR, CDKN1B, NOTCH1, NME1, KDR, ID1, CASP3, RASSF2, FASLG, FLT4, CDKN1A, CDKN2A, VDR, TNFRSF1B, BRAF, XRCC1, MUC1, STIP1, PDGFRA, ANXA4, BRCA2, S100P, JAK1, ITGA2, CRHBP, GATA2, SPARC, TYK2, LGALS1, KRT7, GSTP1, TIA1, HMOX1, IL1R1, USF1, AZGP1, FAS, HOXB2, IL15, STAT6, HOXA10, WT1, HNF1B, PTGS1, ARNT, FLT3, NOS3, MTOR, HOXA11, SOX2, SSTR5, PTGS2, TIMP3, ZEB1, AKR1C3, MKI67, ALDH3A2, CHEK2, PSMD9, XRCC3, AURKA, ATP5B, ESR1, INSR, ITGB3, HSP90AA1, EGFR, JUN, FGF1, ANG, CRYAB, TGFB1, CLOCK, ACTN4, ANXA1, RHOC, MAP3K7, SOD1, PRKCB, FSTL3, APOA1, LTF, S100A6, TP53, SUV39H1, APOE, TERT, MYC, LGALS9, HSPB1, BIRC5, ENO1, ERBB2, PDCD6, FYN, SGK1, SMAD7, MEIS1, NR5A2, RB1, ARID1A, SOX15, KLF11, SNAI1, MAP2K7, |
| NuRD complex | cellular_component | HDAC2, HDAC1, CHD5 |
| oligosaccharyltransferase complex | cellular_component | DAD1 |
| oncostatin-M receptor complex | cellular_component | IL6ST |
| organelle membrane | cellular_component | CYP2A6, CYP2B6, PTGS1, MTOR, SRD5A2, CYP2C19, PTGS2, PGRMC1, CYP2E1, CYP1A2, CYP26A1, CYP1A1, EPHX1, CYP1B1, SRD5A1 |
| other organism cell | cellular_component | C4BPA |
| paranodal junction | cellular_component | AKR1B1 |
| PCAF complex | cellular_component | KAT2B |
| PCNA complex | cellular_component | PCNA |
| PCNA-p21 complex | cellular_component | PCNA, CDKN1A |
| PCSK9-AnxA2 complex | cellular_component | ANXA2 |
| pericentric heterochromatin | cellular_component | DNMT1 |
| pericentriolar material | cellular_component | CEP85 |
| periciliary membrane compartment | cellular_component | KIFAP3 |
| perikaryon | cellular_component | MAPK1, OPRM1, ANXA5, DRD2, CRHBP, ENO2, CCL2, CCR2, ESR1, CRH, NTRK2, AIF1, ESR2, UCN, CRHR2, OLFM1 |
| perinuclear endoplasmic reticulum membrane | cellular_component | PIK3R1 |
| perinuclear region of cytoplasm | cellular_component | GSK3B, AKR1B1, SRC, CDH1, INHBA, NOS2, PLA2G4A, ITGA3, PTGDS, PPARG, IGF2R, CLU, APEX1, CHI3L1, CTNNB1, SERPINF1, NME1, FASLG, SPP1, CSF1, CDKN1A, TNFRSF1B, AGTR2, ANXA4, ITGA2, HMOX1, FAS, CCL2, PLA2G2A, CTLA4, SELE, PTN, BDNF, CCR2, XRCC3, AURKA, ESR1, ITGB1, HSP90AA1, EGFR, ACTN4, S100A6, PTGES, TLR4, ERBB2, SGK1, ANXA2, CTSB, SNCG, TF, GC, COPS5, BAX, S100A13, AIF1, FKBP4, ESR2, SET, ATP7A, TNFSF13B, PTPN22, LIMK1, GPER1, PTPRR, PLA2G16, CX3CL1, LAMC2, Sep-09, OLFM4, PTGES2, SRD5A1 |
| perivitelline space | cellular_component | OVGP1 |
| peroxisomal matrix | cellular_component | CAT |
| peroxisomal membrane | cellular_component | ALDH3A2, CAT |
| peroxisome | cellular_component | XDH, NOS2, VIM, ALDH3A2, SOD1, CAT |
| phagocytic cup | cellular_component | ANXA1, TNF, RAC1, AIF1 |
| phagocytic vesicle | cellular_component | CD36, CLCN3, ITGB5, ITGAV, TLR9 |
| phagocytic vesicle lumen | cellular_component | LTF |
| phagocytic vesicle membrane | cellular_component | HLA-C, HLA-E, HLA-G, HLA-A, TLR2, HLA-B |
| phagolysosome | cellular_component | ADAM8 |
| phosphatidylinositol 3-kinase complex | cellular_component | PIK3R1, PIK3CA, MTOR |
| phosphatidylinositol 3-kinase complex, class IA | cellular_component | PIK3R1, PIK3CA |
| phosphopyruvate hydratase complex | cellular_component | ENO2, ENO1 |
| photoreceptor connecting cilium | cellular_component | KIFAP3 |
| photoreceptor inner segment | cellular_component | ENO2, INHA |
| photoreceptor outer segment | cellular_component | PTGS1, INHA, PROM1 |
| photoreceptor outer segment membrane | cellular_component | PROM1 |
| plasma membrane | cellular_component | GSK3B, MSH6, CRK, ATP5A1, FGFR1, SRC, CDH1, ITGA6, FSHR, MET, STAT3, CRHR1, CD40LG, F2R, WNT5A, MME, ITGA3, TNFRSF1A, FOLR1, FGFR2, IGF2R, HMGB1, LGALS3, GJA1, CFTR, PIK3R1, CD36, ALOX15, F3, DPP6, KIT, VIM, OPRM1, ANXA5, AKT1, SHC1, CTNNB1, EPCAM, CFL1, BRCA1, PTGER4, SLC6A4, KRT19, WNT2, ERBB3, NOTCH1, ACE, DRD2, CLCN3, KDR, FPR1, CASP3, PLCD1, FASLG, CSF1, SDC4, CCR1, CCR5, FLT4, CXCR3, UCHL1, CSF2RB, TNFRSF1B, CD40, BRAF, MUC1, CTNNA1, PDGFRA, AXL, AGTR1, AGTR2, ANXA4, PRLR, HLA-DRB1, S100P, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, SPARC, FLT1, STS, ENO2, GSTP1, IL1R1, C4A, CXCR1, CXCR2, HLA-C, CD44, KITLG, CD79A, AZGP1, PECAM1, FAS, LEPR, TDGF1, NCAM1, HLA-E, KLRC1, IL2RB, LIFR, VCAM1, MMP14, SELP, CTLA4, SELE, HLA-G, IL1RN, IL1R2, ITGB6, SDC1, TACR2, TACR1, EFNA1, PIK3CA, COMT, CDH3, LHCGR, MRC1, SLC6A2, CD82, FLT3, KIR2DL1, KIR2DL3, NOS3, FCER1G, HLA-A, HMOX2, OXTR, SSTR1, L1CAM, SSTR5, BSG, AQP2, CCR2, PTGFR, PTGER3, PTGER2, KIR3DL1, KIR2DS4, CXCL12, CCR9, ATP5B, ESR1, INSR, IGF1, ITGB3, ITGB1, CA2, HSP90AA1 |
| platelet alpha granule | cellular_component | SPARC, FGA, THBS1 |
| platelet alpha granule lumen | cellular_component | VEGFA, CLU, SPARC, HGF, VEGFC, FN1, IGF1, TGFB1, ACTN4, A2M, FGA, SERPINA1, AHSG, TIMP1, PDGFA, SERPINE1, THBS1, FIGF, EGF, IGF2, A1BG, TGFB2, GAS6 |
| platelet alpha granule membrane | cellular_component | CD36, SPARC, PECAM1, SELP, ITGB3 |
| platelet dense granule lumen | cellular_component | TIMP3, RARRES2 |
| platelet dense granule membrane | cellular_component | SELP, ABCC4 |
| platelet dense tubular network | cellular_component | F2R |
| PML body | cellular_component | MTOR, CHEK2, TP53, TERT, RB1, PTEN, EIF3E, PARK7, SIRT1, ISG20 |
| podosome | cellular_component | VCAM1, ADAM8 |
| polysome | cellular_component | MSI1 |
| pore complex | cellular_component | BCL2, BAX |
| postsynapse | cellular_component | OPRM1, AKT1, GHRL, CX3CL1 |
| postsynaptic density | cellular_component | SRC, DRD2, IL1R1, FYN, NTRK2, GPER1 |
| postsynaptic membrane | cellular_component | F2R, COMT, PTEN, NTRK2, NECTIN3, TRPV1 |
| presynapse | cellular_component | SLC6A4, WNT7A, PARK7 |
| presynaptic active zone | cellular_component | SYP, NTRK2, GPER1 |
| presynaptic membrane | cellular_component | SYP, NECTIN1, GPER1 |
| pronucleus | cellular_component | AURKA, HSF1, EZH2 |
| proteasome complex | cellular_component | HSPB1, PSMD10 |
| proteasome regulatory particle | cellular_component | PSMD9, PSMD10 |
| proteasome regulatory particle, base subcomplex | cellular_component | PSMD9, PSMD10 |
| protein complex | cellular_component | GSK3B, HSPD1, DNMT1, MAPK1, CLU, CFTR, AKT1, CTNNB1, BRCA1, NFKB1, AR, CDKN1B, RASSF2, STIP1, PDGFRA, BRCA2, GATA2, IL1R1, SDC1, FLT3, HOXA11, PTGS2, ESR1, HSP90AA1, ACTN4, ANXA1, SOD1, LTF, TP53, MYC, SMAD7, ANXA2, KLK3, HDAC2, SMAD3, RELA, DPYSL2, ACTB, HSF1, PAK1, EIF4EBP1, SMAD2, ADIPOQ, NOD2, FKBP4, SET, HDAC1, FOXP3, ID2, NR0B2, CDKN2A, TP63, PAX2, PLCB3, KSR1, IL1RAP, OGG1, MBD2 |
| protein-DNA complex | cellular_component | HMGA2, CTNNB1, HOXA11, NFE2L2, ESR2, PAX2 |
| proteinaceous extracellular matrix | cellular_component | VEGFA, BMP4, WNT5A, MMP13, FBLN1, BGN, CHI3L1, MMP9, WNT2, COL4A2, LAMA1, SPARC, LGALS1, MMP7, MMP10, VCAN, TIMP2, MMP11, TNC, TIMP3, COL18A1, MMP12, PRELP, FN1, FGF1, TGFB1, SERPINA1, TIMP1, TNFRSF11B, CYR61, WNT7A, LAMA5, ANXA2, COL4A1, MMP1, WNT1, COL5A2, MMP2, MMP3, IL1RL1, WNT4, LOXL1, LAMC2, POSTN, SFTPA1, SPOCK2, MUC4, TIMP4, SMOC2, NTN4, MMP24, DCN, LAMC1, TFF3, CRISPLD2 |
| proton-transporting ATP synthase complex, catalytic core F(1) | cellular_component | ATP5A1, ATP5B |
| proton-transporting two-sector ATPase complex, catalytic domain | cellular_component | ATP5A1, ATP5B |
| proximal neuron projection | cellular_component | PTGER3 |
| pseudopodium | cellular_component | MAPK1, ACTN4, F2RL1 |
| Rad51B-Rad51C-Rad51D-XRCC2 complex | cellular_component | XRCC3 |
| Rad51C-XRCC3 complex | cellular_component | XRCC3 |
| Rb-E2F complex | cellular_component | RB1 |
| rDNA heterochromatin | cellular_component | SUV39H1, SIRT1 |
| receptor complex | cellular_component | FGFR1, ITGA3, TNFRSF1A, ERBB3, NOTCH1, FLT4, VDR, ENG, ITGB5, FLT1, LEPR, KLRC1, LIFR, ITGB6, INSR, ITGB3, ITGB1, EGFR, IGF1R, ERBB2, BMPR1B, NRP1, ITGB2, EGF, SMAD3, NTRK2, LOXL4, KLRD1, P2RX3 |
| recycling endosome | cellular_component | CFTR, AQP2, ITGB1, TNF, TF, GPER1 |
| replication fork | cellular_component | H2AFX, BCL6, DNMT1, XRCC3, TP53 |
| replisome | cellular_component | PCNA |
| respiratory chain | cellular_component | NDUFS1, MT-CO2 |
| respiratory chain complex IV | cellular_component | MT-CO2 |
| ribosome | cellular_component | APEX1, RPL41 |
| RISC complex | cellular_component | DICER1 |
| RISC-loading complex | cellular_component | DICER1 |
| RNA polymerase II transcription factor complex | cellular_component | STAT3, PPARG, HMGA1, VDR, ARNT, NR5A2, HIF1A, NR5A1, SMAD4 |
| RNA-directed RNA polymerase complex | cellular_component | TERT |
| rough endoplasmic reticulum | cellular_component | PTGDS, CCL2, FGA, NTRK2, TP63, P2RX3, CRHR2 |
| rough endoplasmic reticulum lumen | cellular_component | EDN1 |
| ruffle | cellular_component | ITGB1, S100A6, ANXA2, PAK1, AIF1 |
| ruffle membrane | cellular_component | SRC, CFL1, NME1, ITGB3, ITGB1, HSP90AA1, ITGAV, SPRY2, RAC1, PAK1, AIF1, ADAM17 |
| sarcolemma | cellular_component | BGN, OPRM1, ANXA5, KRT19, FAS, VCAM1, BSG, ITGB1, ANXA1, ANXA2, CTSB, PLCB3, PEMT |
| sarcomere | cellular_component | MMP2, TIMP4 |
| sarcoplasmic reticulum | cellular_component | XDH, THBS1 |
| Schmidt-Lanterman incisure | cellular_component | AKR1B1, ANXA2, PTEN |
| Schwann cell microvillus | cellular_component | AKR1B1 |
| Scrib-APC-beta-catenin complex | cellular_component | CTNNB1 |
| secondary lysosome | cellular_component | CRHBP |
| secretory granule | cellular_component | HSPD1, VEGFA, CLCN3, BRCA2, CRHBP, FAS, PLA2G2A, TGFB1, SOD1, PLAT, FSTL3, LTF, THBS1, IL1B, ITGB2, MPO, CTSG, CDC42, ATP7A, PCSK5, OLFM4 |
| secretory granule lumen | cellular_component | APOA1, TF, GHRL |
| semaphorin receptor complex | cellular_component | NRP1, NRP2 |
| senescence-associated heterochromatin focus | cellular_component | HMGA2, HMGA1, CDKN2A |
| septin complex | cellular_component | Sep-09 |
| Shc-EGFR complex | cellular_component | SHC1, EGFR |
| Sin3 complex | cellular_component | HDAC2, HDAC1 |
| site of double-strand break | cellular_component | H2AFX, ATF2 |
| SMAD protein complex | cellular_component | HMGA2, SMAD3, SMAD2, SMAD4 |
| SMAD2-SMAD3 protein complex | cellular_component | SMAD3, SMAD2 |
| smooth endoplasmic reticulum membrane | cellular_component | HSD3B2 |
| smooth muscle contractile fiber | cellular_component | IDO1 |
| SNARE complex | cellular_component | STX5 |
| sodium:potassium-exchanging ATPase complex | cellular_component | ATP1B4 |
| sorting endosome | cellular_component | KDR, NRP1 |
| specific granule | cellular_component | CLCN3, LTF, ADAM8, OLFM4 |
| sperm flagellum | cellular_component | DRD2 |
| spherical high-density lipoprotein particle | cellular_component | CLU, PON1, APOA1, APOA2 |
| spindle | cellular_component | MAPK1, AKT1, AURKA, HSPB1, BIRC5, RB1, NR3C1, SNCG, CDC42, PLK1, ATM |
| spindle microtubule | cellular_component | AURKA, BIRC5, PLK1, KIFAP3 |
| spindle midzone | cellular_component | AURKA, CDC42, PLK1 |
| spindle pole | cellular_component | CTNNB1, CCNB1, AURKA, LATS1, PLK1, CEP85 |
| spindle pole centrosome | cellular_component | AURKA |
| spliceosomal complex | cellular_component | LGALS3 |
| stereocilium bundle | cellular_component | IDO1 |
| storage vacuole | cellular_component | CDC42 |
| stress fiber | cellular_component | ACTN4, TPM3, PTK2, TEK, MST1R, Sep-09 |
| striated muscle thin filament | cellular_component | TMOD3 |
| SWI/SNF complex | cellular_component | RB1, ARID1A, NCR1 |
| synapse | cellular_component | MME, ITGA3, CTNNB1, CCL2, INSR, ITGB1, SYP, COPS5, NRG1, BCL2L1, NECTIN1, GPER1, NECTIN3, CADM1, TRPV1, CADM2, OLFM1, HRH4, PIAS3 |
| synaptic membrane | cellular_component | ITGA3, ITGB1 |
| synaptic vesicle | cellular_component | MME, ANXA5, CLCN3, SYP, COPS5 |
| synaptic vesicle membrane | cellular_component | DRD2, SYP, BCL2L1 |
| synaptonemal complex | cellular_component | MLH1, PLK1 |
| T cell receptor complex | cellular_component | CD4, STOML2 |
| T-tubule | cellular_component | EDNRA, ESR1 |
| telomerase catalytic core complex | cellular_component | TERT |
| telomerase holoenzyme complex | cellular_component | TERT |
| terminal bouton | cellular_component | ESR1, GHRH, SYP, NTRK2, DPYSL2, P2RX3 |
| terminal web | cellular_component | KRT19 |
| TERT-RMRP complex | cellular_component | TERT |
| tertiary granule | cellular_component | ADAM8 |
| Toll-like receptor 1-Toll-like receptor 2 protein complex | cellular_component | TLR2 |
| TORC1 complex | cellular_component | MTOR |
| TORC2 complex | cellular_component | MTOR |
| TRAF2-GSTP1 complex | cellular_component | GSTP1 |
| trans-Golgi network | cellular_component | CDH1, IGF2R, RAC1, ATP7A, GPER1, POSTN, CHST2 |
| trans-Golgi network membrane | cellular_component | IGF2R, HLA-DRB1, LGR5, HLA-DQA1, CD74, HLA-DPB1, MMP24, HLA-DRA |
| trans-Golgi network transport vesicle | cellular_component | IGF2R, ATP7A |
| transcription factor complex | cellular_component | GATA3, YAP1, APEX1, CTNNB1, HMGA1, AHR, GATA2, USF1, HOXA10, HNF1B, ARNT, HOXA11, SOX2, ZEB1, JUN, CLOCK, SMAD7, MEIS1, RB1, FOS, SMAD3, RELA, HIF1A, SMAD2, POU5F1, SMAD4, TP63, GATA6, NAA15, GATA5 |
| transcription factor TFIID complex | cellular_component | TP53 |
| transcriptional repressor complex | cellular_component | CCND1, HMGB1, JUN |
| transcriptionally active chromatin | cellular_component | ESR1 |
| transforming growth factor beta receptor complex | cellular_component | ENG |
| transport vesicle | cellular_component | IGF2R, BGN, IL33, OVGP1, CRISPLD2 |
| transport vesicle membrane | cellular_component | CLCN3, HLA-DRB1, AQP2, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
| U12-type spliceosomal complex | cellular_component | YBX1 |
| ubiquitin ligase complex | cellular_component | BRCA1 |
| vacuole | cellular_component | CD74, MST1R |
| varicosity | cellular_component | TNFRSF1B, CRHBP, CRH, UCN, CRHR2 |
| very-low-density lipoprotein particle | cellular_component | APOA1, APOA2, APOE |
| vesicle | cellular_component | CETP, MIF, AKT1, CFL1, MUC1, GSTP1, IL1RN, ANXA1, ANXA2, PROM1, IL1B, TF, NOD2, STX5, MUC16, MUC4, RHOA |
| vesicle membrane | cellular_component | CLCN3, ANXA4 |
| viral envelope | cellular_component | ERVW-1 |
| virion | cellular_component | ERVW-1 |
| voltage-gated potassium channel complex | cellular_component | DPP6 |
| Weibel-Palade body | cellular_component | EDN1 |
| Wnt signalosome | cellular_component | GSK3B, CTNNB1, WNT2 |
| XY body | cellular_component | H2AFX, DNMT3A |
| Z disc | cellular_component | ANXA5, CTNNB1, KRT19, CRYAB, ACTN4, HSPB1, PAK1 |
| zonula adherens | cellular_component | CTNNA1 |
| zymogen granule | cellular_component | PLA2G4A |
| (1->3)-beta-D-glucan binding | molecular_function | PTX3 |
| (R)-limonene 6-monooxygenase activity | molecular_function | CYP2C19 |
| (S)-limonene 6-monooxygenase activity | molecular_function | CYP2C19 |
| (S)-limonene 7-monooxygenase activity | molecular_function | CYP2C19 |
| 1-acyl-2-lysophosphatidylserine acylhydrolase activity | molecular_function | PLA2G16 |
| 1-alkyl-2-acetylglycerophosphocholine esterase activity | molecular_function | PAFAH1B2 |
| 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity | molecular_function | CYP24A1 |
| 1-phosphatidylinositol binding | molecular_function | SCARB1 |
| 1-phosphatidylinositol-3-kinase activity | molecular_function | FGFR1, FGF2, FGFR2, PIK3R1, PIK3CA, FGF1, TLR9, ATM, IRS2 |
| 1-phosphatidylinositol-3-kinase regulator activity | molecular_function | PIK3R1 |
| 1-phosphatidylinositol-4-phosphate 3-kinase activity | molecular_function | PIK3CA |
| 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | molecular_function | HSD11B2 |
| 14-3-3 protein binding | molecular_function | AKT1, IRS2 |
| 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | molecular_function | HPGD, ABCC4 |
| 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity | molecular_function | AKR1C3 |
| 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity | molecular_function | HSD17B2, AKR1C1 |
| 17-alpha-hydroxyprogesterone aldolase activity | molecular_function | CYP17A1 |
| 2 iron, 2 sulfur cluster binding | molecular_function | XDH, NDUFS1 |
| 25-hydroxycholecalciferol-24-hydroxylase activity | molecular_function | CYP24A1 |
| 3'-5' exonuclease activity | molecular_function | APEX1 |
| 3'-5'-exoribonuclease activity | molecular_function | ISG20 |
| 3-beta-hydroxy-delta5-steroid dehydrogenase activity | molecular_function | HSD3B2 |
| 3-chloroallyl aldehyde dehydrogenase activity | molecular_function | ALDH3A2 |
| 3-keto sterol reductase activity | molecular_function | HSD17B7 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase activity | molecular_function | SRD5A2, SRD5A1 |
| 3-phosphoinositide-dependent protein kinase binding | molecular_function | INSR, SGK1 |
| 4 iron, 4 sulfur cluster binding | molecular_function | NDUFS1 |
| 5'-deoxyribose-5-phosphate lyase activity | molecular_function | HMGA2, HMGA1 |
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity | molecular_function | OGG1 |
| Ac-Asp-Glu binding | molecular_function | FOLH1 |
| acetylcholinesterase activity | molecular_function | BCHE |
| acetylglucosaminyltransferase activity | molecular_function | XYLT2 |
| acetyltransferase activity | molecular_function | NAT2, KAT2B, NAA15 |
| acid phosphatase activity | molecular_function | ACP1 |
| acireductone dioxygenase [iron(II)-requiring] activity | molecular_function | ADI1 |
| actin binding | molecular_function | CFL1, ACE, CCR5, ITGB1, ANG, ACTN4, TPM3, GC, PTK2, CXCR4, NOD2, AIF1, YWHAH, TAGLN, TMOD3, CALD1 |
| actin filament binding | molecular_function | SLC6A4, CTNNA1, EGFR, ACTN4, AIF1 |
| actin monomer binding | molecular_function | NOS3 |
| actinin binding | molecular_function | NFKB1, PROM1, RELA |
| activating transcription factor binding | molecular_function | PPARG, JUN, RELA, SMAD2, HDAC1 |
| activin binding | molecular_function | ENG, FST, FSTL3, SMAD7 |
| acyl-L-homoserine-lactone lactonohydrolase activity | molecular_function | PON1 |
| acylglycerol lipase activity | molecular_function | LIPC |
| adenosine deaminase activity | molecular_function | ADA |
| adipokinetic hormone receptor activity | molecular_function | ADIPOR2, ADIPOR1 |
| adiponectin binding | molecular_function | ADIPOR2, ADIPOR1 |
| ADP binding | molecular_function | GCLC, MSH2, MSH6 |
| adrenergic receptor activity | molecular_function | DRD2 |
| adrenergic receptor binding | molecular_function | C1QBP |
| adrenomedullin receptor binding | molecular_function | ADM |
| advanced glycation end-product receptor activity | molecular_function | AGER |
| aldehyde dehydrogenase (NAD) activity | molecular_function | ALDH3A2 |
| aldehyde dehydrogenase [NAD(P)+] activity | molecular_function | ALDH3A2 |
| alditol:NADP+ 1-oxidoreductase activity | molecular_function | AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
| aldo-keto reductase (NADP) activity | molecular_function | AKR1B1, AKR1D1, AKR1C3, AKR1C1 |
| alpha-2A adrenergic receptor binding | molecular_function | UCHL1 |
| alpha-actinin binding | molecular_function | PPARG, ITGB1 |
| alpha-amylase activity | molecular_function | AMY2A |
| alpha-catenin binding | molecular_function | CTNNB1 |
| alpha-mannosidase activity | molecular_function | MANEA |
| alpha-N-acetylglucosaminidase activity | molecular_function | NAGLU |
| amide binding | molecular_function | SRD5A2, SRD5A1 |
| aminoacylase activity | molecular_function | CAT |
| aminopeptidase activity | molecular_function | BLMH |
| anaphase-promoting complex binding | molecular_function | PTEN, PLK1 |
| androgen binding | molecular_function | AR, SHBG |
| androgen receptor activity | molecular_function | AR |
| androgen receptor binding | molecular_function | CTNNB1, BRCA1, PRKCB, RB1, TGFB1I1, PARK7, FOXP1 |
| androsterone dehydrogenase (B-specific) activity | molecular_function | AKR1C1 |
| androsterone dehydrogenase activity | molecular_function | AKR1C3 |
| angiotensin type I receptor activity | molecular_function | AGTR1 |
| angiotensin type II receptor activity | molecular_function | AGTR1, AGTR2 |
| anion transmembrane transporter activity | molecular_function | SLC26A8 |
| anion:anion antiporter activity | molecular_function | SLC26A8 |
| ankyrin binding | molecular_function | CDH1 |
| ankyrin repeat binding | molecular_function | RELA |
| annealing helicase activity | molecular_function | ANXA1 |
| anti-Mullerian hormone receptor activity | molecular_function | AMHR2 |
| antigen binding | molecular_function | CD40, AZGP1, HLA-G, KIR2DL3, TGFB1, MICA, MICB, ULBP2 |
| antioxidant activity | molecular_function | PRDX6, SOD1, APOE, HP, CAT |
| antiporter activity | molecular_function | CLCN3 |
| apolipoprotein A-I binding | molecular_function | SCARB1 |
| apolipoprotein A-I receptor binding | molecular_function | APOA1, CDC42 |
| apolipoprotein binding | molecular_function | LIPC, SCARB1 |
| apolipoprotein receptor binding | molecular_function | APOA1, APOA2 |
| arachidonate 12-lipoxygenase activity | molecular_function | ALOX15 |
| arachidonate 15-lipoxygenase activity | molecular_function | ALOX15, PTGS2 |
| arachidonic acid binding | molecular_function | PPARG |
| arachidonic acid epoxygenase activity | molecular_function | CYP2A6, CYP2B6, CYP2C19, CYP2E1 |
| arginase activity | molecular_function | ARG2 |
| arginine binding | molecular_function | NOS2, NOS3 |
| aromatase activity | molecular_function | CYP19A1, CYP1A2, CYP1A1, CYP1B1 |
| aryl hydrocarbon receptor activity | molecular_function | AHR, ARNT |
| aryl hydrocarbon receptor binding | molecular_function | ARNT |
| aryl sulfotransferase activity | molecular_function | SULT1E1 |
| arylamine N-acetyltransferase activity | molecular_function | NAT2 |
| aryldialkylphosphatase activity | molecular_function | PON1 |
| arylesterase activity | molecular_function | PON1, CA2 |
| arylsulfatase activity | molecular_function | ARSH |
| aspartic-type endopeptidase activity | molecular_function | CASP3, CTSD |
| aspartic-type endopeptidase inhibitor activity | molecular_function | WFDC2 |
| AT DNA binding | molecular_function | HMGA2, HMGA1 |
| ATP binding | molecular_function | GCLC, GSK3B, MSH2, MSH6, MLH1, HSPD1, ATP5A1, FGFR1, SRC, MET, MAPK1, FGFR2, CFTR, KIT, AKT1, ERBB3, NME1, CLCN3, KDR, FLT4, HSPA6, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, PIK3CA, FLT3, MTOR, MAT2A, HSPA4, MKI67, CHEK2, XRCC3, AURKA, ATP5B, INSR, HSP90AA1, EGFR, MAP3K7, IGF1R, PRKCB, TP53, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, ABCC4, KALRN, PAK4, CSF1R, ABCB1, RUNX3, PLK1, PTK2, DICER1, NTRK2, TYRO3, ACTB, TEK, PAK1, ACLY, NOD2, FKBP4, ATP7A, MST1R, ATM, NOD1, LIMK1, DAPK1, PIM2, AMHR2, ABCG2, TRPV1, PMS2, P2RX3, KSR1, CHD5, ATAD3A |
| ATP citrate synthase activity | molecular_function | ACLY |
| ATP-binding and phosphorylation-dependent chloride channel activity | molecular_function | CFTR |
| ATP-dependent helicase activity | molecular_function | CHD5 |
| ATPase activity | molecular_function | MSH2, MSH6, MLH1, HSPD1, ATP5A1, CLU, CFTR, ATP5B, HSP90AA1, ABCC4, ABCB1, ABCG2, PMS2 |
| ATPase activity, coupled | molecular_function | HSPA6 |
| ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | molecular_function | ABCC4 |
| ATPase activity, coupled to transmembrane movement of substances | molecular_function | CFTR, ABCC4, ABCB1, ABCG2 |
| ATPase binding | molecular_function | AR, ESR1, PGR |
| ATPase-coupled anion transmembrane transporter activity | molecular_function | CFTR, ABCC4 |
| AU-rich element binding | molecular_function | TIA1, ELAVL1 |
| beta-2-microglobulin binding | molecular_function | HLA-E, HLA-A, MICA, CD1A |
| beta-amyloid binding | molecular_function | APOA1, BCHE, APOE, CD74, TGFB2 |
| beta-catenin binding | molecular_function | GSK3B, CDH1, AR, CTNNA1, ESR1, SMAD7, FOXO1 |
| beta-endorphin receptor activity | molecular_function | OPRM1 |
| beta-glucuronidase activity | molecular_function | HPSE |
| beta-tubulin binding | molecular_function | GJA1, GABARAPL1 |
| BH domain binding | molecular_function | BAX |
| BH3 domain binding | molecular_function | BCL2, BCL2L1, BAX, MCL1 |
| bHLH transcription factor binding | molecular_function | USF1, PSMD9, SMAD3, SIRT1, TWIST1, USF2 |
| bicarbonate transmembrane transporter activity | molecular_function | CFTR, SLC26A8 |
| bile acid binding | molecular_function | AKR1C2, AKR1C1 |
| binding, bridging | molecular_function | PDCD6, GAS6 |
| bis(5'-adenosyl)-triphosphatase activity | molecular_function | FHIT |
| BMP binding | molecular_function | ENG, GREM1 |
| BMP receptor binding | molecular_function | BMP4, BMP6 |
| bradykinin receptor binding | molecular_function | ACE, AGTR1 |
| brain-derived neurotrophic factor binding | molecular_function | NTRK2 |
| brain-derived neurotrophic factor-activated receptor activity | molecular_function | NTRK2 |
| bubble DNA binding | molecular_function | HMGB1 |
| C-C chemokine binding | molecular_function | CCR1, CCR5 |
| C-C chemokine receptor activity | molecular_function | CCR1, CCR5, CCR2, CCR9, CCR7, CCR8 |
| C-C motif chemokine 19 receptor activity | molecular_function | CCR7 |
| C-C motif chemokine 21 receptor activity | molecular_function | CCR7 |
| C-X-C chemokine binding | molecular_function | HMGB1, CXCR3, CXCR6 |
| C-X-C chemokine receptor activity | molecular_function | CXCR3, CXCR1, CXCR2, CXCR6, CXCR4 |
| C-X3-C chemokine binding | molecular_function | ITGB3, ITGB1, ITGAV |
| C2H2 zinc finger domain binding | molecular_function | HMGA2, GATA2, WT1, EHMT2, MBD2 |
| C5L2 anaphylatoxin chemotactic receptor binding | molecular_function | C3 |
| cadherin binding | molecular_function | CTNNB1, CTNNA1, PROM1, OLFM4, MMP24 |
| cadherin binding involved in cell-cell adhesion | molecular_function | EPCAM |
| cadmium ion binding | molecular_function | NOS3 |
| caffeine oxidase activity | molecular_function | CYP1A2 |
| calcidiol binding | molecular_function | GC |
| calcitriol binding | molecular_function | VDR |
| calcitriol receptor activity | molecular_function | VDR |
| calcium channel activity | molecular_function | TRPV1 |
| calcium channel regulator activity | molecular_function | PRKCB, SGK1, NPY |
| calcium ion binding | molecular_function | CDH1, PLA2G4A, MMP13, FBLN1, ANXA5, MBL2, NOTCH1, PLCD1, BRAF, ANXA4, S100P, SPARC, MMP10, VCAN, PLA2G2A, MMP14, CDH3, MMP11, PON1, MMP12, ACTN4, ANXA1, S100A6, PDCD6, CRP, PCDH17, ANXA2, THBS1, EGF, APCS, MMP1, AMY2A, MMP3, GAS6, PLCB1, S100A13, AIF1, ADAM8, JAG1, NUCB2, DLL4, PLCB3, CD69, IHH, NOTCH4, SPOCK2, SMOC2, MMP24 |
| calcium-dependent cysteine-type endopeptidase activity | molecular_function | PDCD6, CAPN5 |
| calcium-dependent phospholipase A2 activity | molecular_function | PLA2G4A, PLA2G2A |
| calcium-dependent phospholipid binding | molecular_function | PLA2G4A, ANXA5, ANXA4, ANXA1, ANXA2 |
| calcium-dependent protein binding | molecular_function | MMP13, MBL2, ANXA4, S100P, SELP, ANXA1, A2M, S100A6, PDCD6, ANXA2 |
| calcium-dependent protein kinase C activity | molecular_function | CCL3, PRKCB |
| calcium-dependent protein kinase regulator activity | molecular_function | HMGB1 |
| calcium-release channel activity | molecular_function | TRPV1 |
| calcium-transporting ATPase activity | molecular_function | ANXA5 |
| calmodulin binding | molecular_function | NOS2, MAP2, NOS3, PLCB1, DAPK1, TRPV1, PLCB3, CALD1 |
| calmodulin-dependent protein kinase activity | molecular_function | DAPK1 |
| cAMP response element binding | molecular_function | HMGA2, ATF2, JUN, CREB3L1 |
| cAMP response element binding protein binding | molecular_function | ATF2 |
| cAMP-dependent protein kinase regulator activity | molecular_function | CXCL10 |
| carbohydrate binding | molecular_function | LGALS3, CHI3L1, MBL2, LGALS1, VCAN, KLRC1, SELP, SELE, MRC1, BSG, NPTX2, LGALS9, KRT1, APCS, FCER2, NECTIN1, KLRD1, IL2, CD69, SFTPA1, CLEC11A, KLRK1 |
| carbonate dehydratase activity | molecular_function | CA2 |
| carboxylic acid binding | molecular_function | AKR1C2, AKR1C1 |
| carboxylic ester hydrolase activity | molecular_function | LIPC, BCHE |
| carboxypeptidase activity | molecular_function | ACE, BLMH, FOLH1, CPB2 |
| CARD domain binding | molecular_function | NOD2, NOD1 |
| cardiolipin binding | molecular_function | STOML2 |
| catalase activity | molecular_function | CAT |
| catalytic activity | molecular_function | XDH, PRDX6, HPGD, MTHFR, STS, HSD3B2, HSD17B1, GSTZ1, BCHE, PNP, AMY2A, CYP1A1, EPHX1, GALT, PAK1, ACLY, FOLH1, ILKAP, ARSH, OLFM4, OGG1, FHIT |
| catechol O-methyltransferase activity | molecular_function | COMT |
| cation binding | molecular_function | AMY2A, ILKAP |
| cation-transporting ATPase activity | molecular_function | ATP7A |
| CCR chemokine receptor binding | molecular_function | CCL21, CCL22, CCL16, CCL19, CX3CL1, CCL17, CCL11 |
| CCR1 chemokine receptor binding | molecular_function | CCL5, CCL3, CCL7 |
| CCR10 chemokine receptor binding | molecular_function | CCL25, CXCL13, CCL19 |
| CCR2 chemokine receptor binding | molecular_function | CCL2, CCR2, CCL7 |
| CCR4 chemokine receptor binding | molecular_function | CCL5 |
| CCR5 chemokine receptor binding | molecular_function | STAT3, CCL5, CCL3, JAK1 |
| CCR7 chemokine receptor binding | molecular_function | CCL21, CCL19 |
| CD4 receptor binding | molecular_function | FYN |
| CD40 receptor binding | molecular_function | CD40LG |
| CD8 receptor binding | molecular_function | FYN |
| cell adhesion molecule binding | molecular_function | FGFR1, SRC, CDH1, VCAM1, ITGB3, ITGB1, FGA, CLDN7, ITGB2, NECTIN1, NECTIN3, ADAM8, CADM1, POSTN, NECTIN4, CADM2 |
| centromeric DNA binding | molecular_function | MSH2 |
| channel activity | molecular_function | BCL2, BAX |
| channel inhibitor activity | molecular_function | BCL2 |
| channel-conductance-controlling ATPase activity | molecular_function | CFTR |
| chaperone binding | molecular_function | HSPD1, CLU, CDKN1B, STIP1, SOD1, TP53, BIRC5, CP, BAX |
| chemoattractant activity | molecular_function | FGF2, VEGFA, BMP4, CCL5, HMGB1, LGALS3, MIF, CCL3, HGF, SAA1, VEGFC, CXCL12, CCL16, FIGF |
| chemoattractant activity involved in axon guidance | molecular_function | WNT5A |
| chemokine (C-C motif) ligand 19 binding | molecular_function | CCR7 |
| chemokine (C-C motif) ligand 21 binding | molecular_function | CCR7 |
| chemokine (C-C motif) ligand 5 binding | molecular_function | CCR1, CCR5, CCR2 |
| chemokine (C-C motif) ligand 7 binding | molecular_function | CCR1 |
| chemokine activity | molecular_function | CCL5, CXCL8, CCL3, CXCL1, CCL2, CXCL2, CXCL5, CXCL12, CXCL10, CCL25, CCL21, CCL22, CCL16, CXCL13, CXCL14, C5, CCL19, CCL7, CX3CL1, CXCL6, CCL17, CXCL16, CCL27, CCL11 |
| chemokine binding | molecular_function | CXCR3 |
| chemokine receptor activity | molecular_function | CCR1, CCR5, CXCR3, CXCR1, CCR2, CCR9, CXCR6, CXCR4, CCR7, CCR8 |
| chemokine receptor antagonist activity | molecular_function | CCL5 |
| chemokine receptor binding | molecular_function | CCL5, CXCL12, CCL25, CCL21, CCL19, CXCL16 |
| chemorepellent activity | molecular_function | APOA1, NRG1, SEMA3A, SEMA3C |
| chitin binding | molecular_function | CHI3L1, OVGP1 |
| chitinase activity | molecular_function | CHI3L1, OVGP1 |
| chloride channel activity | molecular_function | CFTR, CLCN3, SLC26A8 |
| chloride channel inhibitor activity | molecular_function | CFTR |
| chloride channel regulator activity | molecular_function | CFTR, SGK1 |
| chloride ion binding | molecular_function | ACE, AMY2A |
| chloride transmembrane transporter activity | molecular_function | CFTR |
| cholestenone 5-alpha-reductase activity | molecular_function | SRD5A2, SRD5A1 |
| cholesterol binding | molecular_function | CETP, STAR, APOA1, APOA2, APOE, SYP |
| cholesterol monooxygenase (side-chain-cleaving) activity | molecular_function | CYP11A1 |
| cholesterol transporter activity | molecular_function | CETP, STAR, APOA1, APOA2, APOE |
| choline binding | molecular_function | BCHE, CRP |
| cholinesterase activity | molecular_function | BCHE |
| chondroitin sulfate proteoglycan binding | molecular_function | PTN |
| choriogonadotropin hormone binding | molecular_function | LHCGR |
| choriogonadotropin hormone receptor activity | molecular_function | LHCGR |
| chromatin binding | molecular_function | MSH6, MLH1, GATA3, YAP1, BCL6, DNMT1, PCNA, PPARG, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, NOTCH1, GATA2, ZEB1, ESR1, EGFR, JUN, PRKCB, TP53, SUV39H1, MEIS1, NR5A2, SOX15, FOS, MPO, HDAC2, SMAD3, RELA, DNMT3A, HES5, FOXO1, NR5A1, HSF1, SMAD2, NFKB2, KAT2B, EZH2, SMAD4, GPER1, DNMT3B, TP63, GATA6, GATA5, CREB3L1, MBD2 |
| chromatin DNA binding | molecular_function | BCL6, STAT3, APEX1, NOTCH1, CLOCK, ACTN4, SMAD3, RELA, EZH2 |
| ciliary neurotrophic factor binding | molecular_function | IL6R |
| ciliary neurotrophic factor receptor activity | molecular_function | IL6R, IL6ST, LIFR |
| ciliary neurotrophic factor receptor binding | molecular_function | IL6ST, CNTF, LIFR |
| cis-stilbene-oxide hydrolase activity | molecular_function | EPHX1 |
| co-receptor binding | molecular_function | BMP4, DKK1 |
| co-SMAD binding | molecular_function | SMAD3, SMAD2 |
| cobalt ion binding | molecular_function | BIRC5 |
| cocaine binding | molecular_function | SLC6A4 |
| coenzyme binding | molecular_function | GCLC |
| cofactor binding | molecular_function | C3, BIRC5, SGK1, ACLY |
| collagen binding | molecular_function | ITGA3, MMP13, MMP9, ITGA2, SPARC, CD44, FN1, ITGB1, PDGFA, SMAD7, CTSB, SMAD3, PAK1, SMAD4, DCN |
| collagen binding involved in cell-matrix adhesion | molecular_function | ITGA2, ITGB1 |
| collagen receptor activity | molecular_function | ITGA2 |
| collagen V binding | molecular_function | THBS1 |
| complement component C1q binding | molecular_function | C4A, PTX3, CRP, APCS, C1QBP |
| connexin binding | molecular_function | GJA1 |
| copper ion binding | molecular_function | MT-CO2, ANG, SOD1, IL1A, TP53, CP, PARK7, S100A13, ATP7A, LOXL4, LOXL1 |
| copper ion transmembrane transporter activity | molecular_function | ATP7A |
| copper-dependent protein binding | molecular_function | FKBP4, ATP7A |
| copper-exporting ATPase activity | molecular_function | ATP7A |
| core promoter binding | molecular_function | HMGA2, NOTCH1, CLOCK, RB1, HDAC2, PARK7, HDAC1, FOXP3, EZH2 |
| core promoter proximal region DNA binding | molecular_function | HNF1B |
| core promoter proximal region sequence-specific DNA binding | molecular_function | GATA3, SMAD3, SMAD4, PAX2 |
| core promoter sequence-specific DNA binding | molecular_function | GATA3, PPARG, ESR1, CLOCK, TP53, ESR2, SIRT1, KLF10 |
| coreceptor activity | molecular_function | CCR5, ITGB3, ITGB1, ITGAV, CD4, CXCR6, NRP1, CXCR4, NECTIN1, CCR8 |
| corticotrophin-releasing factor receptor activity | molecular_function | CRHR1, CRHR2 |
| corticotropin-releasing hormone binding | molecular_function | CRHBP |
| corticotropin-releasing hormone receptor 1 binding | molecular_function | CRH, UCN |
| corticotropin-releasing hormone receptor 2 binding | molecular_function | CRH, UCN, UCN2 |
| corticotropin-releasing hormone receptor activity | molecular_function | CRHR2 |
| coumarin 7-hydroxylase activity | molecular_function | CYP2A6 |
| crossover junction endodeoxyribonuclease activity | molecular_function | XRCC3 |
| CTP binding | molecular_function | HSP90AA1 |
| cullin family protein binding | molecular_function | CCDC22 |
| cupric ion binding | molecular_function | PARK7 |
| cuprous ion binding | molecular_function | PARK7 |
| CX3C chemokine receptor binding | molecular_function | CX3CL1 |
| CXCR chemokine receptor binding | molecular_function | CXCL1, CXCL2, CXCL5, CXCL12, CXCL6 |
| CXCR3 chemokine receptor binding | molecular_function | CXCL10, CXCL13 |
| CXCR5 chemokine receptor binding | molecular_function | CXCL13 |
| cyclin binding | molecular_function | CDKN1A |
| cyclin-dependent protein kinase activating kinase activity | molecular_function | CDKN1A |
| cyclin-dependent protein serine/threonine kinase activity | molecular_function | CCNB1 |
| cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular_function | CDKN1B, CASP3, CDKN1A, CDKN2A, KAT2B |
| cyclin-dependent protein serine/threonine kinase regulator activity | molecular_function | CCND1 |
| cysteine-type endopeptidase activator activity involved in apoptotic process | molecular_function | CASP1, CDKN1B, CASP3, NOD1 |
| cysteine-type endopeptidase activity | molecular_function | CASP1, CASP3, UCHL1, CTSB, CTSD, BLMH |
| cysteine-type endopeptidase activity involved in apoptotic process | molecular_function | CASP1, CASP3 |
| cysteine-type endopeptidase activity involved in execution phase of apoptosis | molecular_function | CASP3 |
| cysteine-type endopeptidase inhibitor activity | molecular_function | AHSG, BIRC5, WFDC2 |
| cysteine-type endopeptidase inhibitor activity involved in apoptotic process | molecular_function | BIRC5, GAS6 |
| cysteine-type endopeptidase regulator activity involved in apoptotic process | molecular_function | FOXL2 |
| cysteine-type peptidase activity | molecular_function | CASP1, CASP3, UCHL1, CAPN5, CTSB, BLMH |
| cytochrome-c oxidase activity | molecular_function | MT-CO2 |
| cytokine activity | molecular_function | INHBA, FGF2, VEGFA, BMP4, CD40LG, WNT5A, CCL5, HMGB1, IL10, IL12B, CXCL8, MIF, CCL3, WNT2, TNFSF10, FASLG, SPP1, CSF1, CNTF, CXCL1, KITLG, CCL2, IL15, LIF, IL9, IL1RN, CXCL2, IL11, BMP6, IL12A, IL13, CXCL5, CXCL12, GREM1, IFNG, TGFB1, INHA, IL1A, TIMP1, TNF, CXCL10, CCL25, TNFRSF11B, CCL21, CCL22, WNT7A, MSTN, CCL16, CXCL13, GDF9, IL1B, CXCL14, IL33, LTA, CSF2, WNT1, IL4, IL5, IL6, EDN1, TGFB2, NRG1, ADIPOQ, IL18, CCL19, TNFSF13B, IL24, IL23A, CCL7, CX3CL1, IL2, CXCL6, IL16, IL17A, IL22, IL27, CCL17, TSLP, IL17F, NODAL, GDF15, CXCL16, IL37, CCL27, CCL11 |
| cytokine binding | molecular_function | KIT, LIFR, NRP1, NRP2, CD74, CSF1R, PARK7, CXCR4, IL17F |
| cytokine receptor activity | molecular_function | F3, IL12B, CSF2RB, PRLR, IL6R, IL6ST, CD44, LEPR, IL2RB, LIFR, FLT3, CD74, IL1RL1, IL11RA, IL20RB, IL20RA |
| cytokine receptor binding | molecular_function | IL12B, MIF, IL15, IL9, IL13, IL4, IL17A, IL17F |
| cytoskeletal protein binding | molecular_function | CRYAB, ANXA2 |
| damaged DNA binding | molecular_function | MSH2, MSH6, H2AFX, PCNA, HMGB1, APEX1, BRCA1, XRCC1, TP53, TP63, OGG1 |
| dATP binding | molecular_function | HSP90AA1 |
| deacetylase activity | molecular_function | HDAC2, HDAC1, SIRT1 |
| deaminase activity | molecular_function | ADA |
| death receptor binding | molecular_function | CASP3, FASLG |
| delta4-3-oxosteroid 5beta-reductase activity | molecular_function | AKR1D1, AKR1C3 |
| demethylase activity | molecular_function | CYP1A2, CYP1A1 |
| deoxyribonuclease activity | molecular_function | NME1 |
| deoxyribonuclease I activity | molecular_function | DICER1 |
| dihydropyrimidinase activity | molecular_function | DPYSL2 |
| dihydrosphingosine-1-phosphate phosphatase activity | molecular_function | SGPP2 |
| dihydrotestosterone 17-beta-dehydrogenase activity | molecular_function | AKR1C3 |
| dinitrosyl-iron complex binding | molecular_function | GSTP1 |
| dinucleotide insertion or deletion binding | molecular_function | MSH2, PCNA |
| dinucleotide repeat insertion binding | molecular_function | MSH2 |
| dioxygenase activity | molecular_function | ALOX15, IDO1, PTGS1, PTGS2, ADI1, TET3, TET2, TET1 |
| dipeptidase activity | molecular_function | FOLH1 |
| dipeptidyl-peptidase activity | molecular_function | DPP6 |
| disaccharide binding | molecular_function | LGALS9 |
| DNA (cytosine-5-)-methyltransferase activity | molecular_function | DNMT1, DNMT3A, DNMT3B |
| DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates | molecular_function | DNMT1, DNMT3A, DNMT3B |
| DNA binding | molecular_function | MSH2, MSH6, H2AFX, EGR1, GATA3, BCL6, STAT3, NR2F2, DNMT1, PCNA, CDX1, HMGA2, PPARG, MAPK1, HMGB1, APEX1, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, AHR, VDR, BRCA2, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ZEB1, XRCC3, ESR1, JUN, ANG, CLOCK, LTF, TP53, TERT, MYC, ENO1, SMAD7, MEIS1, NR5A2, RB1, ARID1A, SOX15, KLF11, SNAI1, FOS, NR3C1, PRDM1, PGR, PRM1, XRCC4, RUNX3, YBX1, SMAD3, RELA, DNMT3A, FOXL2, HIF1A, FOXP1, HES5, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, SET, NFKB2, POU5F1, FOXP3, EZH2, ATM, STAT4, SMAD4, HIST3H3, TWIST1, DNMT3B, HIST2H3A, NR0B2, ZNF366, CDKN2A, TP63, EMX2, KLF10, GATA6, PAX2, USF2, NUCB2, PMS2, DLX5, KLF9, PTGES2, TBPL2, CHD5, NANOG, GATA5, TBX21, AHRR, OGG1, TET3, MAF, TET2, TET1, CREB3L1, MBD2 |
| DNA binding, bending | molecular_function | HMGA2, HMGB1 |
| DNA ligase activity | molecular_function | XRCC1 |
| DNA N-glycosylase activity | molecular_function | OGG1 |
| DNA polymerase binding | molecular_function | PCNA, HMGB1 |
| DNA polymerase processivity factor activity | molecular_function | PCNA |
| DNA replication origin binding | molecular_function | HSPD1 |
| DNA-(apurinic or apyrimidinic site) lyase activity | molecular_function | HMGA2, APEX1, HMGA1, OGG1 |
| DNA-dependent ATPase activity | molecular_function | XRCC3 |
| DNA-dependent protein kinase activity | molecular_function | HMGA2, ATM |
| DNA-methyltransferase activity | molecular_function | DNMT1, DNMT3A, DNMT3B |
| dolichyl-diphosphooligosaccharide-protein glycotransferase activity | molecular_function | DAD1 |
| dopachrome isomerase activity | molecular_function | MIF |
| dopamine binding | molecular_function | DRD2 |
| dopamine neurotransmitter receptor activity | molecular_function | DRD2 |
| dopamine neurotransmitter receptor activity, coupled via Gi/Go | molecular_function | DRD2 |
| dopamine:sodium symporter activity | molecular_function | SLC6A2 |
| double-strand/single-strand DNA junction binding | molecular_function | MSH2 |
| double-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular_function | APEX1 |
| double-stranded DNA binding | molecular_function | MSH2, MSH6, DNMT1, HMGB1, CTNNB1, NFKB1, USF1, XRCC3, EGFR, JUN, TP53, NR5A2, FOS, YBX1, SMAD3, PARK7, HES5, NR5A1, SMAD2, TP63 |
| double-stranded DNA exodeoxyribonuclease activity | molecular_function | APEX1 |
| double-stranded DNA-dependent ATPase activity | molecular_function | ANXA1 |
| double-stranded RNA binding | molecular_function | HSPD1, HMGB1, VIM, TLR3, DICER1, ELAVL1 |
| double-stranded telomeric DNA binding | molecular_function | APEX1 |
| drug binding | molecular_function | PPARG, FOLR1, ACE, DRD2, GSTP1, PNP, IL2RA, CXCR4, ESR2, PPARA, GPER1 |
| drug transmembrane transporter activity | molecular_function | ABCG2 |
| dynein binding | molecular_function | BCL2L11 |
| dystroglycan binding | molecular_function | MAP2, AGR2 |
| E-box binding | molecular_function | GATA3, AHR, ZEB1, CLOCK, MYC, TWIST1 |
| electron carrier activity | molecular_function | XDH, AKR1B1, NDUFS1, CYP19A1, IDO1, CYP1A2, PTGES2, SRD5A1 |
| endodeoxyribonuclease activity | molecular_function | APEX1 |
| endogenous lipid antigen binding | molecular_function | CD1A |
| endonuclease activity | molecular_function | APEX1, ANG, DICER1, PMS2, OGG1 |
| endopeptidase activity | molecular_function | MME, MMP9, CASP1, ACE, CMA1, MMP12, CTSB, MMP1, KLK3, MMP3, PCSK5, PAPPA |
| endopeptidase inhibitor activity | molecular_function | C4A, A2M, AHSG, C3, SLPI, SPINK1, C5, WFDC2 |
| endoribonuclease activity | molecular_function | APEX1, DICER1 |
| endoribonuclease activity, producing 5'-phosphomonoesters | molecular_function | DICER1 |
| endothelin A receptor binding | molecular_function | EDN1 |
| endothelin B receptor binding | molecular_function | EDN1 |
| endothelin receptor activity | molecular_function | EDNRA |
| enhancer binding | molecular_function | AHR, ARNT, SMAD3, SMAD2 |
| enhancer sequence-specific DNA binding | molecular_function | GATA3, ATF2, GATA2, GATA5 |
| enzyme activator activity | molecular_function | CXCL1, PSAP, DNMT3L, MMP24 |
| enzyme binding | molecular_function | MSH2, H2AFX, SRC, CCND1, PCNA, PPARG, IGF2R, CFTR, AKT1, CTNNB1, BRCA1, HMGA1, AR, NOTCH1, NME1, HSPA6, CD40, XRCC1, CYP2A6, IL6R, GSTM1, HMOX1, USF1, CYP2C19, PTGS2, ESR1, ITGB3, EGFR, JUN, TGFB1, A2M, CYP2E1, SOD1, APOA1, BCHE, TP53, LGALS9, BIRC5, CD4, CYP1A2, RB1, MAP2K7, SLPI, PGR, CAT, CYP1A1, RAC1, PTEN, HDAC2, SMAD3, RELA, PARK7, HIF1A, PLAUR, PLCB1, NR5A1, NOD2, ESR2, HDAC1, MST1R, SIRT1, YWHAH, DNMT3L, PIAS3 |
| enzyme inhibitor activity | molecular_function | NOTCH1, TIMP2, TIMP3, NGF, TIMP1, TIMP4 |
| enzyme regulator activity | molecular_function | DNMT3L |
| eoxin A4 synthase activity | molecular_function | ALOX15 |
| ephrin receptor binding | molecular_function | CRK, SRC, SHC1, EFNA1, FYN |
| epidermal growth factor receptor binding | molecular_function | SHC1, AGR2, EGF |
| epidermal growth factor-activated receptor activity | molecular_function | EGFR |
| epoxide hydrolase activity | molecular_function | EPHX1 |
| ErbB-2 class receptor binding | molecular_function | NRG1, MUC4 |
| ErbB-3 class receptor binding | molecular_function | PIK3R1, ERBB2, NRG1 |
| estradiol 17-beta-dehydrogenase activity | molecular_function | HSD17B1, HSD17B2, HSD17B7 |
| estradiol binding | molecular_function | ESR2 |
| estrogen receptor activity | molecular_function | ESR1, ESR2, GPER1 |
| estrogen receptor binding | molecular_function | SRC, DNMT1, PCNA, PPARG, CTNNB1, FOXL2, ZNF366, RERG |
| estrogen response element binding | molecular_function | ESR1, ESR2 |
| estrone sulfotransferase activity | molecular_function | SULT1E1 |
| euchromatin binding | molecular_function | CTNNB1 |
| eukaryotic initiation factor 4E binding | molecular_function | EIF4EBP1 |
| excitatory extracellular ligand-gated ion channel activity | molecular_function | TRPV1 |
| exogenous lipid antigen binding | molecular_function | CD1A |
| exonuclease activity | molecular_function | APEX1, ISG20 |
| exopeptidase activity | molecular_function | MME, ACE |
| exoribonuclease II activity | molecular_function | ISG20 |
| extracellular ATP-gated cation channel activity | molecular_function | P2RX3 |
| extracellular matrix binding | molecular_function | VEGFA, BGN, SPP1, SPARC, ITGB3, ITGAV, CYR61, THBS1, SPOCK2, DCN |
| extracellular matrix constituent conferring elasticity | molecular_function | COL4A1 |
| extracellular matrix constituent, lubricant activity | molecular_function | MUC17, MUC4 |
| extracellular matrix protein binding | molecular_function | ITGAV |
| extracellular matrix structural constituent | molecular_function | FBLN1, BGN, CHI3L1, COL4A2, LAMA1, VCAN, PRELP, CD4, COL4A1, COL5A2, LAMC1 |
| fatty acid binding | molecular_function | PTGDS |
| ferric iron binding | molecular_function | TF |
| ferric iron transmembrane transporter activity | molecular_function | TF |
| ferrous iron binding | molecular_function | TF, TET2 |
| ferroxidase activity | molecular_function | CP |
| fibrinogen binding | molecular_function | FBLN1, THBS1 |
| fibroblast growth factor binding | molecular_function | FGFR1, FGFR2, ITGB3, ITGAV, THBS1, CXCL13, S100A13 |
| fibroblast growth factor receptor binding | molecular_function | FGF2, FGF1 |
| fibroblast growth factor-activated receptor activity | molecular_function | FGFR1, FGFR2 |
| fibronectin binding | molecular_function | VEGFA, ITGA3, MMP13, FBLN1, IGFBP3, SDC4, IGFBP5, ITGB3, ITGB1, ITGAV, FSTL3, THBS1 |
| filamin binding | molecular_function | OPRM1 |
| FK506 binding | molecular_function | FKBP4, FKBP5 |
| flavin adenine dinucleotide binding | molecular_function | XDH, NOS2, MTHFR, MAOA, NOS3 |
| flavonoid 3'-monooxygenase activity | molecular_function | CYP1A1 |
| flavonol 3-sulfotransferase activity | molecular_function | SULT1E1 |
| FMN binding | molecular_function | NOS2, NOS3 |
| folic acid binding | molecular_function | FOLR1 |
| folic acid receptor activity | molecular_function | FOLR1 |
| folic acid transporter activity | molecular_function | FOLR1 |
| follicle-stimulating hormone activity | molecular_function | FSHB |
| follicle-stimulating hormone receptor activity | molecular_function | FSHR |
| four-way junction DNA binding | molecular_function | MSH2, MSH6, HMGB1, XRCC3 |
| frizzled binding | molecular_function | WNT5A, WNT2, WNT7A, WNT1, WNT4 |
| frizzled-2 binding | molecular_function | WNT5A |
| fucose binding | molecular_function | SELP |
| G-protein alpha-subunit binding | molecular_function | F2R, IGF2R, OPRM1, F2RL1, LPAR3 |
| G-protein beta-subunit binding | molecular_function | F2R, OPRM1, F2RL1 |
| G-protein coupled acetylcholine receptor activity | molecular_function | HRH4 |
| G-protein coupled peptide receptor activity | molecular_function | FSHR, LHCGR, KISS1R |
| G-protein coupled receptor activity | molecular_function | FSHR, CRHR1, F2R, IGF2R, OPRM1, PTGER4, DRD2, FPR1, CCR1, CCR5, CXCR3, AGTR1, AGTR2, EDNRA, CXCR1, CXCR2, TACR2, TACR1, LHCGR, OXTR, SSTR1, SSTR5, CCR2, PTGFR, PTGER3, PTGER2, CCR9, LGR5, CXCR6, CXCR4, F2RL1, GPER1, KISS1R, CRHR2, SFRP4, HRH4, LPAR3, NPY, CCR7, CCR8, RXFP1 |
| G-protein coupled receptor binding | molecular_function | SAA1, CCL2, FYN, PSAP, GHRL, UCN, PROK1, NPY, UCN2 |
| GABA receptor binding | molecular_function | GABARAPL1 |
| galactose binding | molecular_function | ENG, LGALS9 |
| gamma-catenin binding | molecular_function | CDH1, CTNNA1 |
| gamma-tubulin binding | molecular_function | NME1, BRCA2 |
| gap junction channel activity | molecular_function | GJA1 |
| gap junction channel activity involved in cardiac conduction electrical coupling | molecular_function | GJA1 |
| gap junction channel activity involved in cell communication by electrical coupling | molecular_function | GJA1 |
| GDP binding | molecular_function | KRAS, RERG |
| geranylgeranyl reductase activity | molecular_function | AKR1C3 |
| ghrelin receptor binding | molecular_function | GHRL |
| globoside alpha-N-acetylgalactosaminyltransferase activity | molecular_function | GBGT1 |
| glucocorticoid receptor activity | molecular_function | NR3C1 |
| glucocorticoid receptor binding | molecular_function | STAT3, FLT3, FKBP4, YWHAH |
| glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity | molecular_function | NR3C1 |
| glutamate binding | molecular_function | GCLC |
| glutamate-cysteine ligase activity | molecular_function | GCLC |
| glutathione binding | molecular_function | GSTP1, GSTM1, PTGES, PTGES2 |
| glutathione peroxidase activity | molecular_function | PRDX6, GPX3, GSTT1, GSTZ1, GPX1 |
| glutathione transferase activity | molecular_function | GSTP1, GSTM1, GSTT1, GSTZ1 |
| glyceraldehyde oxidoreductase activity | molecular_function | AKR1B1 |
| glycerol channel activity | molecular_function | AQP2, AQP8, AQP5 |
| glycerol transmembrane transporter activity | molecular_function | AQP2 |
| glycoprotein binding | molecular_function | FGFR1, CDH1, ITGA3, IGF2R, VIM, LGALS1, AZGP1, SELP, SDC1, ITGB1, TGFB1, SERPINA1, PLAT, CD4, FYN, BMPR1B, THBS1, ITGB2 |
| glycoprotein endo-alpha-1,2-mannosidase activity | molecular_function | MANEA |
| glycosaminoglycan binding | molecular_function | BGN, ENG, VCAN, PTN, SPOCK2, SMOC2, DCN, CRISPLD2 |
| glycosphingolipid binding | molecular_function | SELP, IL2 |
| glyoxalase (glycolic acid-forming) activity | molecular_function | PARK7 |
| glyoxalase III activity | molecular_function | PARK7 |
| GMP binding | molecular_function | KRAS |
| granulocyte macrophage colony-stimulating factor receptor binding | molecular_function | CSF2 |
| growth factor activity | molecular_function | INHBA, FGF2, VEGFA, BMP4, IL10, IL12B, LEP, CSF1, HGF, CNTF, CXCL1, KITLG, TDGF1, LIF, IL9, TYMP, IL11, PTN, MDK, BMP6, BDNF, IL12A, NTF4, VEGFC, CXCL12, IGF1, FGF1, TGFB1, INHA, NGF, TIMP1, PDGFA, MSTN, FIGF, GDF9, DKK1, EGF, IGF2, AMH, CSF2, IL4, IL5, IL6, TGFB2, NRG1, JAG1, NUDT6, PROK1, IL2, NODAL, GDF15, CLEC11A |
| growth factor binding | molecular_function | IGFBP2, IGFBP3, ERBB3, KDR, FLT4, IGFBP5, IL6ST, FLT1, IGFBP1, LIFR, IGFBP4, A2M, ERBB2, CYR61, NRP1, NRP2, TEK, IGFBP7, HTRA1 |
| growth factor receptor binding | molecular_function | SRC, FYN |
| growth hormone receptor binding | molecular_function | JAK1, TYK2 |
| growth hormone-releasing hormone activity | molecular_function | GHRH, GHRL |
| growth hormone-releasing hormone receptor binding | molecular_function | GHRH |
| GTP binding | molecular_function | NME1, INSR, HSP90AA1, RHOC, DIRAS3, NRAS, KRAS, CDC42, RAC1, FKBP4, DAPK1, RND3, Sep-09, RHOA, RERG |
| GTP-dependent protein binding | molecular_function | CDC42, RAC1 |
| GTPase activating protein binding | molecular_function | CDH1, AKT1, PLCD1 |
| GTPase activator activity | molecular_function | JUN, A2M, KALRN, PLCB1, ERRFI1 |
| GTPase activity | molecular_function | DIRAS3, KRAS, CDC42, RAC1, RND3, Sep-09, RHOA, RERG |
| GTPase binding | molecular_function | HSP90AA1, ENO1, YBX1, STOML2 |
| guanine/thymine mispair binding | molecular_function | MSH2, MSH6, MLH1 |
| guanyl-nucleotide exchange factor activity | molecular_function | KALRN |
| H3 histone acetyltransferase activity | molecular_function | BRCA2 |
| H3K27me3 modified histone binding | molecular_function | CHD5 |
| H4 histone acetyltransferase activity | molecular_function | BRCA2 |
| heat shock protein binding | molecular_function | NFKB1, HSPA6, HDAC2, BAX, FKBP4, FKBP5, LIMK1 |
| helicase activity | molecular_function | ANXA1, DICER1, CHD5 |
| heme binding | molecular_function | SRC, NOS2, CYP19A1, CYP2A6, HMOX1, IDO1, CYP2B6, LPO, PTGS1, NOS3, CYP2C19, PTGS2, CYP17A1, PGRMC1, CYP2E1, CYP11A1, CYP1A2, PGRMC2, CYP26A1, CAT, CYP1A1, MPO, CYP1B1, PTGES2, CYP24A1 |
| heme oxygenase (decyclizing) activity | molecular_function | HMOX1, HMOX2 |
| heme transporter activity | molecular_function | HPX, ABCG2 |
| hemoglobin binding | molecular_function | HP |
| heparan sulfate binding | molecular_function | PTN |
| heparan sulfate proteoglycan binding | molecular_function | FST, LIPC |
| heparanase activity | molecular_function | HPSE |
| heparin binding | molecular_function | FGFR1, FGF2, VEGFA, BMP4, CCL5, FGFR2, MMP7, SAA1, LIPC, CCL2, SELP, PTN, MDK, PRELP, FN1, FGF1, ANG, LTF, APOE, CXCL10, CYR61, NRP1, MSTN, THBS1, CXCL13, NRP2, MPO, CTSG, CCL7, CXCL6, LAMC2, POSTN, SMOC2, CRISPLD2 |
| hepatocyte growth factor-activated receptor activity | molecular_function | MET |
| hepoxilin A3 synthase activity | molecular_function | ALOX15 |
| hepoxilin-epoxide hydrolase activity | molecular_function | ALOX15 |
| heteroduplex DNA loop binding | molecular_function | MSH2 |
| high mobility group box 1 binding | molecular_function | AGER |
| high-density lipoprotein particle binding | molecular_function | CD36, APOA1, APOA2, SCARB1 |
| high-density lipoprotein particle receptor activity | molecular_function | SCARB1 |
| high-density lipoprotein particle receptor binding | molecular_function | APOA1, APOA2 |
| histamine receptor activity | molecular_function | HRH4 |
| histone acetyltransferase activity | molecular_function | ATF2, BRCA2, CLOCK, KAT2B |
| histone acetyltransferase binding | molecular_function | EGR1, PCNA, PLA2G4A, TP53, HIF1A, KAT2B, FOXP3 |
| histone binding | molecular_function | H2AFX, PRKCB, SET, SIRT1, HIST3H3, HIST2H3A |
| histone deacetylase activity | molecular_function | HDAC2, HDAC1, SIRT1 |
| histone deacetylase binding | molecular_function | CCND1, DNMT1, USF1, HOXA10, HSP90AA1, PRDM1, RAC1, RELA, HIF1A, KAT2B, HDAC1, FOXP3, DNMT3B |
| histone deacetylase inhibitor activity | molecular_function | UCN |
| histone kinase activity | molecular_function | CCNB1 |
| histone kinase activity (H3-T6 specific) | molecular_function | PRKCB |
| histone methyltransferase activity | molecular_function | SUV39H1, EZH2 |
| histone methyltransferase activity (H3-K27 specific) | molecular_function | EZH2, EHMT2 |
| histone methyltransferase activity (H3-K9 specific) | molecular_function | SUV39H1, EHMT2, SUV39H2 |
| histone serine kinase activity | molecular_function | AURKA |
| histone-lysine N-methyltransferase activity | molecular_function | SUV39H1, EZH2, EHMT2, SUV39H2 |
| HLA-A specific inhibitory MHC class I receptor activity | molecular_function | LILRB1 |
| HLA-B specific inhibitory MHC class I receptor activity | molecular_function | KIR3DL1, LILRB1 |
| HLA-C specific inhibitory MHC class I receptor activity | molecular_function | KIR2DS5 |
| HLH domain binding | molecular_function | SIRT1 |
| HMG box domain binding | molecular_function | GATA3, JUN, DLX5 |
| hormone activity | molecular_function | INHBA, LEP, ADM, IGF1, INHA, CCL25, CGA, FSHB, LHB, PRL, GHRH, IGF2, AMH, RLN1, EDN1, CRH, ADIPOQ, GHRL, UCN, SST, HAMP, RETN, NPY, STC1, UCN2 |
| hormone binding | molecular_function | ESR1, ESR2, GPER1, AMHR2, UCN2 |
| hormone receptor binding | molecular_function | SRC |
| Hsp70 protein binding | molecular_function | CDKN1B, STIP1, FGF1, NOD2 |
| Hsp90 protein binding | molecular_function | AHR, KDR, HIF1A, NOD2 |
| hyaluronic acid binding | molecular_function | CD44, VCAN, C1QBP |
| hyalurononglucosaminidase activity | molecular_function | CD44 |
| hydrolase activity | molecular_function | PLA2G4A, MME, MMP13, PRDX6, CFTR, APEX1, MMP9, CASP1, ACE, CASP3, PLCD1, UCHL1, STS, MMP7, MMP10, LIPC, PLA2G2A, MMP14, CMA1, MMP11, ACP1, PON1, MMP12, ATP5B, ANG, PLAT, LTF, BCHE, CAPN5, CTSB, PTP4A3, PLAU, ADA, MMP1, AMY2A, CTSD, KLK3, EPHX1, ABCB1, MMP2, MMP3, CTSG, COPS5, PTEN, ARG2, HDAC2, DICER1, PARK7, HPSE, DPYSL2, PLCB1, ATP7A, HDAC1, SIRT1, PTPN22, RARRES3, ADAM17, PCSK5, ADAM8, BLMH, TPSAB1, DUSP2, PTPRR, PLA2G16, PMS2, NUDT6, NAGLU, PLCB3, PAFAH1B2, FOLH1, PAPPA, ILKAP, IHH, ARSH, MANEA, PLCD3, CHD5, HTRA1, ISG20, CPB2, MMP24, OGG1, TPSB2, FHIT, SGPP2, SMPD3 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | molecular_function | ATP5A1, ATP5B |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular_function | CHD5 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | molecular_function | DPYSL2 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | molecular_function | KLK3 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | molecular_function | ARG2 |
| hydrolase activity, acting on ester bonds | molecular_function | BCHE |
| hydrolase activity, acting on glycosyl bonds | molecular_function | AMY2A, HPSE, NAGLU, OGG1 |
| hydrolase activity, hydrolyzing O-glycosyl compounds | molecular_function | CHI3L1, OVGP1 |
| I-SMAD binding | molecular_function | CTNNB1, SMAD7, TGFB1I1, SMAD2, SMAD4 |
| ICAM-3 receptor activity | molecular_function | ITGB2 |
| identical protein binding | molecular_function | BCL2, FGFR1, INHBA, VEGFA, STAT3, PCNA, PPARG, FBLN1, MAPK1, IGF2R, IL12B, VIM, MMP9, AKT1, CCL3, NFKB1, ERBB3, NME1, DRD2, BRAF, ANXA4, HGF, FAS, LEPR, NCAM1, STAT6, COL18A1, FN1, CHEK2, ESR1, ITGB3, HSP90AA1, EGFR, JUN, CRYAB, SOD1, SERPINA1, IGF1R, APOA1, BCHE, TP53, APOE, TNF, HSPB1, BIRC5, ERBB2, PDCD6, CLDN5, RB1, CLDN4, MSTN, TLR3, CLDN3, THBS1, CLDN7, CD74, SYP, CDC42, PTEN, SMAD3, RELA, BCL2L1, DNMT3A, PARK7, BAX, ACTB, ADIPOQ, SIRT1, NOD1, SMAD4, AGER, DAPK1, TP63, FHIT, ADIPOR2, ADIPOR1 |
| IgE binding | molecular_function | LGALS3, FCER1G, FCER2 |
| IgE receptor activity | molecular_function | FCER1G |
| IgG binding | molecular_function | FCER1G |
| immunoglobulin binding | molecular_function | CD4 |
| indanol dehydrogenase activity | molecular_function | AKR1C3, AKR1C1 |
| indoleamine 2,3-dioxygenase activity | molecular_function | IDO1 |
| inhibin binding | molecular_function | INHBA, INHA |
| inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | molecular_function | PTEN |
| insulin binding | molecular_function | PIK3R1, INSR, IGF1R |
| insulin receptor binding | molecular_function | SRC, PIK3R1, SHC1, IGF1, IGF1R, IGF2, IRS2 |
| insulin receptor substrate binding | molecular_function | PIK3R1, PIK3CA, INSR, IGF1R |
| insulin-activated receptor activity | molecular_function | INSR |
| insulin-like growth factor binding | molecular_function | IGF2R, IGFBP2, IGFBP3, IGFBP5, IGFBP1, IGFBP4, IGF1R, CYR61, IGFBP7, HTRA1 |
| insulin-like growth factor I binding | molecular_function | ITGA6, IGFBP2, IGFBP3, IGFBP5, IGFBP1, IGFBP4, INSR, ITGB3, ITGAV, IGF1R |
| insulin-like growth factor II binding | molecular_function | IGF2R, IGFBP2, IGFBP3, IGFBP5, IGFBP1, IGFBP4, INSR |
| insulin-like growth factor receptor binding | molecular_function | PIK3R1, SHC1, INSR, IGF1, IGF2, YWHAH |
| insulin-like growth factor-activated receptor activity | molecular_function | IGF2R, IGF1R |
| integrin binding | molecular_function | GSK3B, SRC, ITGA6, ITGA3, FBLN1, KDR, ITGA2, VCAM1, TIMP2, MMP14, ITGB6, FN1, IGF1, ITGB1, FGF1, ACTN4, CYR61, LAMA5, THBS1, ICAM1, FCER2, NRG1, ADAM17, ADAM22, CX3CL1 |
| interferon receptor activity | molecular_function | IL22RA1 |
| interferon-gamma receptor binding | molecular_function | IFNG |
| interleukin-1 binding | molecular_function | A2M |
| interleukin-1 receptor activity | molecular_function | IL1R1, IL1R2, IL1RL1, IL1RAP |
| interleukin-1 receptor antagonist activity | molecular_function | IL1RN |
| interleukin-1 receptor binding | molecular_function | IL1RN, IL1A, IL1B, TLR9, IL1RAP, IL37 |
| interleukin-1 Type I receptor antagonist activity | molecular_function | IL1RN |
| interleukin-1 Type II receptor antagonist activity | molecular_function | IL1RN |
| interleukin-1, Type I receptor binding | molecular_function | IL1RN |
| interleukin-1, Type I, activating receptor activity | molecular_function | IL1R1 |
| interleukin-1, Type II receptor binding | molecular_function | IL1RN |
| interleukin-1, Type II, blocking receptor activity | molecular_function | IL1R2 |
| interleukin-10 receptor activity | molecular_function | IL10RB |
| interleukin-10 receptor binding | molecular_function | IL10 |
| interleukin-11 binding | molecular_function | IL6ST |
| interleukin-11 receptor activity | molecular_function | IL6ST |
| interleukin-11 receptor binding | molecular_function | IL11 |
| interleukin-12 alpha subunit binding | molecular_function | IL12B |
| interleukin-12 beta subunit binding | molecular_function | IL12A |
| interleukin-12 receptor binding | molecular_function | IL12B, IL12A |
| interleukin-13 receptor binding | molecular_function | IL13 |
| interleukin-2 binding | molecular_function | IL2RB, IL2RA |
| interleukin-2 receptor activity | molecular_function | IL2RB, IL2RA |
| interleukin-2 receptor binding | molecular_function | GATA3, IL2 |
| interleukin-20 binding | molecular_function | IL22RA1, IL20RB, IL20RA |
| interleukin-22 receptor binding | molecular_function | IL22 |
| interleukin-23 receptor binding | molecular_function | IL12B, IL23A |
| interleukin-27 binding | molecular_function | IL12A |
| interleukin-27 receptor activity | molecular_function | IL6ST |
| interleukin-27 receptor binding | molecular_function | IL27 |
| interleukin-3 receptor activity | molecular_function | CSF2RB |
| interleukin-33 binding | molecular_function | IL1RL1 |
| interleukin-33 receptor activity | molecular_function | IL1RL1 |
| interleukin-4 receptor binding | molecular_function | IL4 |
| interleukin-5 receptor activity | molecular_function | CSF2RB |
| interleukin-5 receptor binding | molecular_function | IL5 |
| interleukin-6 binding | molecular_function | IL6R, IL6ST |
| interleukin-6 receptor activity | molecular_function | IL6R, IL6ST |
| interleukin-6 receptor binding | molecular_function | IL6R, IL6ST, CNTF, IL6, ADAM17 |
| interleukin-8 binding | molecular_function | CXCR1, CXCR2, A2M |
| interleukin-8 receptor activity | molecular_function | CXCR1, CXCR2 |
| interleukin-8 receptor binding | molecular_function | CXCL8 |
| interleukin-9 receptor binding | molecular_function | IL9 |
| intermediate filament binding | molecular_function | NME1 |
| intramolecular transferase activity, phosphotransferases | molecular_function | PGM1 |
| intronic transcription regulatory region sequence-specific DNA binding | molecular_function | BCL6 |
| ion channel activity | molecular_function | CLCN3, TRPV1, P2RX3 |
| ion channel binding | molecular_function | SRC, CTNNB1, HSP90AA1, ACTN4, FYN, ID2, YWHAH |
| ion transmembrane transporter activity | molecular_function | GJA1, S100A6 |
| ionotropic glutamate receptor binding | molecular_function | GSK3B, CTNNB1, DRD2, IL1R1 |
| iron channel inhibitor activity | molecular_function | HAMP |
| iron ion binding | molecular_function | XDH, ALOX15, CYP19A1, CYP2A6, CYP2B6, NOS3, CYP2C19, CYP17A1, CYP2E1, CYP11A1, LTF, CYP1A2, CYP26A1, CYP1A1, ADI1, CYP1B1, CYP24A1, TET1 |
| iron-sulfur cluster binding | molecular_function | XDH, NDUFS1 |
| isomerase activity | molecular_function | PGM1, PTGDS, MIF, HSD3B2, GSTZ1, PTGES, FKBP4, FKBP5, PTGES2 |
| JUN kinase binding | molecular_function | GSTP1, PTK2 |
| JUN kinase kinase activity | molecular_function | MAP2K7 |
| kappa-type opioid receptor binding | molecular_function | IL2 |
| keratin filament binding | molecular_function | VIM, SIRT1 |
| ketoreductase activity | molecular_function | AKR1C3 |
| ketosteroid monooxygenase activity | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
| kinase activator activity | molecular_function | IL2 |
| kinase activity | molecular_function | GSK3B, FGFR1, SRC, CCND1, MET, MAPK1, FGFR2, KIT, AKT1, CCNB1, CCL3, ERBB3, NME1, KDR, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, PIK3CA, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, PLK1, PTK2, NTRK2, TYRO3, TEK, PAK1, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2 |
| kinase binding | molecular_function | SRC, CTNNB1, FAS, ITGB1, RB1, SNAI1, PARK7, ERRFI1, PTPN22, KLRK1 |
| kinase inhibitor activity | molecular_function | AHSG |
| kinase regulator activity | molecular_function | GSTP1 |
| kinesin binding | molecular_function | ACTB, KIFAP3 |
| kininogen binding | molecular_function | CTSB, C1QBP |
| kisspeptin receptor binding | molecular_function | KISS1 |
| L-dopa decarboxylase activator activity | molecular_function | PARK7 |
| lactose binding | molecular_function | LGALS1 |
| lamin binding | molecular_function | PLCB1 |
| laminin binding | molecular_function | ITGA3, LGALS3, ITGA2, LGALS1, ITGB1, THBS1 |
| laminin-1 binding | molecular_function | NTN4 |
| leptin receptor activity | molecular_function | LEPR |
| leukemia inhibitory factor receptor activity | molecular_function | IL6ST, LIFR |
| leukemia inhibitory factor receptor binding | molecular_function | LIF |
| ligand-dependent nuclear receptor binding | molecular_function | ARID1A, SRA1 |
| ligand-dependent nuclear receptor transcription coactivator activity | molecular_function | FGF2, PPARG, HMGA1, ACTN4, PRKCB, PPRC1, SRA1 |
| ligase activity | molecular_function | GCLC, BRCA1, UCHL1, XRCC4, TRIM36, PIAS3 |
| lipase activity | molecular_function | LIPC |
| lipase inhibitor activity | molecular_function | APOA1, APOA2 |
| lipid binding | molecular_function | CETP, CD36, ALOX15, AR, RBP1, LIPC, PTGS1, PTGS2, STAR, ESR1, SERPINA6, PGRMC1, APOA1, APOA2, APOE, C3, NR5A2, PGRMC2, NR3C1, PGR, SHBG, PSAP, PTEN, BAX, S100A13, NR5A1, STOML2, ESR2, PPARA, LPAR3, SULT1E1 |
| lipid transporter activity | molecular_function | CETP, APOA1, APOA2, APOE, SFTPA1, SLCO2A1 |
| lipoic acid binding | molecular_function | INSR |
| lipopeptide binding | molecular_function | CD1A |
| lipopolysaccharide binding | molecular_function | HSPD1, HMGB1, SELP, TLR2, TLR4, SCARB1 |
| lipopolysaccharide receptor activity | molecular_function | TLR2, TLR4, SCARB1 |
| lipoprotein particle binding | molecular_function | CD36, APOA1, APOE |
| lipoteichoic acid receptor activity | molecular_function | CD36 |
| lithocholic acid binding | molecular_function | VDR |
| lithocholic acid receptor activity | molecular_function | VDR |
| long-chain-alcohol oxidase activity | molecular_function | ALDH3A2 |
| long-chain-aldehyde dehydrogenase activity | molecular_function | ALDH3A2 |
| low-density lipoprotein particle binding | molecular_function | CD36, LIPC, CRP, THBS1, SCARB1 |
| low-density lipoprotein particle receptor binding | molecular_function | MMP13, APOE, CRP, DKK1 |
| low-density lipoprotein receptor activity | molecular_function | CD36, CXCL16 |
| LRR domain binding | molecular_function | KRAS |
| luteinizing hormone receptor activity | molecular_function | LHCGR |
| lyase activity | molecular_function | HMGB1, APEX1, ENO2, CA2, CYP17A1, ENO1, PTGES2, OGG1 |
| lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | molecular_function | KAT2B |
| lysophosphatidic acid receptor activity | molecular_function | LPAR3 |
| lysophospholipase activity | molecular_function | PLA2G4A, LIPC |
| macromolecular complex binding | molecular_function | MTOR |
| macrophage colony-stimulating factor receptor activity | molecular_function | CSF1R, MST1R |
| macrophage colony-stimulating factor receptor binding | molecular_function | CSF1 |
| macrophage migration inhibitory factor binding | molecular_function | CD74 |
| magnesium ion binding | molecular_function | GCLC, MSH2, MSH6, PGM1, NME1, S100P, ENO2, COMT, MAP3K7, ENO1, LATS1, MAP2K7, PTEN |
| maleylacetoacetate isomerase activity | molecular_function | GSTZ1 |
| mannose binding | molecular_function | IGF2R, MBL2, MRC1, BSG |
| MAP kinase activity | molecular_function | MAPK1 |
| MAP kinase kinase activity | molecular_function | MAP2K7 |
| MAP kinase kinase kinase activity | molecular_function | BRAF, EGFR, MAP3K7 |
| MAP kinase tyrosine/serine/threonine phosphatase activity | molecular_function | DUSP2 |
| MAP-kinase scaffold activity | molecular_function | KSR1 |
| MDM2/MDM4 family protein binding | molecular_function | PPARA, CDKN2A |
| medium-chain-aldehyde dehydrogenase activity | molecular_function | ALDH3A2 |
| mercury ion binding | molecular_function | FN1, PARK7 |
| metal chelating activity | molecular_function | APOE |
| metal ion binding | molecular_function | XDH, NDUFS1, PGM1, EGR1, CDH1, GATA3, ITGA6, BCL6, NOS2, NR2F2, DNMT1, PLA2G4A, MME, ITGA3, PPARG, MMP13, IGFBP3, APEX1, ALOX15, KIT, CYP19A1, MMP9, ATF2, BRCA1, SLC6A4, AR, TNFSF10, NOTCH1, NME1, ACE, PLCD1, CDKN1A, VDR, BRAF, CYP2A6, PRLR, S100P, JAK1, ITGA2, GATA2, SPARC, STS, ENO2, MMP7, MMP10, HMOX1, PLA2G2A, IDO1, TIMP2, MMP14, WT1, CYP2B6, COMT, LPO, CDH3, PTGS1, SLC6A2, MMP11, PON1, NOS3, HMOX2, MAT2A, CYP2C19, PTGS2, TIMP3, ZEB1, COL18A1, MMP12, NPTX2, CHEK2, ESR1, ITGB1, CA2, CYP17A1, MT-CO2, ITGAV, CRYAB, ACTN4, ANXA1, MAP3K7, CYP2E1, CYP11A1, SOD1, FGA, PRKCB, TIMP1, LTF, S100A6, TP53, SUV39H1, TERT, BIRC5, ENO1, CYP1A2, PDCD6, LATS1, FYN, BMPR1B, SMAD7, NR5A2, CRP, KLF11, SNAI1, MAP2K7, NRP1, TGFB1I1, ANGPT2, NR3C1, CYP26A1, KALRN, NRP2, PRDM1, PGR, CP, ITGB2, ADA, TF, APCS, HPX, MMP1, CAT, AMY2A, CYP1A1, MPO, COL5A2, FCER2, GALT, MMP2, MMP3, ADI1, COPS5, ARG2, SMAD3, DICER1, DNMT3A, FOXP1, GAS6, S100A13, NR5A1, SMAD2, ACLY, AIF1, ESR2, PPARA, ATP7A, FOXP3, SIRT1, SMAD4, ADAM17, LIMK1, EHMT2, LOX |
| metallocarboxypeptidase activity | molecular_function | FOLH1, CPB2 |
| metallodipeptidase activity | molecular_function | ACE |
| metalloendopeptidase activity | molecular_function | MME, MMP13, MMP9, MMP7, MMP10, MMP14, MMP11, MMP12, MMP1, MMP2, MMP3, ADAM17, ADAM8, ADAM22, PAPPA, MMP24 |
| metalloendopeptidase inhibitor activity | molecular_function | TIMP2, TIMP3, NGF, TIMP1, TIMP4 |
| metallopeptidase activity | molecular_function | MME, MMP13, MMP9, ACE, MMP7, MMP10, MMP14, MMP11, MMP12, MMP1, MMP2, MMP3, COPS5, ADAM17, ADAM8, ADAM22, FOLH1, PAPPA, CPB2, MMP24 |
| methionine adenosyltransferase activity | molecular_function | MAT2A |
| methotrexate binding | molecular_function | FOLR1 |
| methyl-CpG binding | molecular_function | DNMT1, MBD2 |
| methylated histone binding | molecular_function | MSH6 |
| methylcytosine dioxygenase activity | molecular_function | TET3, TET2, TET1 |
| methylenetetrahydrofolate reductase (NAD(P)H) activity | molecular_function | MTHFR |
| methyltransferase activity | molecular_function | DNMT1, COMT, SUV39H1, PRDM1, DNMT3A, EZH2, EHMT2, DNMT3B, SUV39H2, PEMT |
| MH1 domain binding | molecular_function | HMGA2 |
| MH2 domain binding | molecular_function | HMGA2 |
| MHC class I protein binding | molecular_function | ATP5A1, HLA-E, ATP5B, KLRK1, LILRB1 |
| MHC class I protein complex binding | molecular_function | KLRC1, KLRD1 |
| MHC class I receptor activity | molecular_function | KIR3DS1, LILRB1 |
| MHC class Ib protein binding, via antigen binding groove | molecular_function | KLRD1 |
| MHC class Ib receptor activity | molecular_function | KLRK1 |
| MHC class II protein binding | molecular_function | CD4, CD74 |
| MHC class II protein binding, via antigen binding groove | molecular_function | CD74 |
| MHC class II protein complex binding | molecular_function | HSP90AA1, HLA-DRB1, CD74, HLA-DRA |
| MHC class II receptor activity | molecular_function | HLA-DRB1, HLA-DQA1, HLA-DRA |
| microsatellite binding | molecular_function | HEY1 |
| microtubule binding | molecular_function | MAP2, CRYAB, BIRC5, BCL2L11, PLK1, DPYSL2, OGG1 |
| mineralocorticoid receptor activity | molecular_function | GPER1 |
| miRNA binding | molecular_function | SOX2, POU5F1 |
| misfolded protein binding | molecular_function | CLU |
| mismatched DNA binding | molecular_function | MSH2, MSH6, MLH1, PMS2 |
| mitochondrial ribosome binding | molecular_function | C1QBP |
| mitogen-activated protein kinase binding | molecular_function | ACE, SIRT1, DUSP2 |
| mitogen-activated protein kinase kinase binding | molecular_function | ACE, BRAF, KSR1 |
| mitogen-activated protein kinase kinase kinase binding | molecular_function | MAPK1, MAP2K7, CDC42 |
| modified amino acid binding | molecular_function | MTHFR |
| molecular_function | molecular_function | G0S2, CDH3, NPTX2, TPM3, A1BG, COL5A2, NRM, AIF1, MST1, TFF3 |
| molybdopterin cofactor binding | molecular_function | XDH |
| monoamine transmembrane transporter activity | molecular_function | SLC6A4, SLC6A2 |
| monocarboxylic acid transmembrane transporter activity | molecular_function | BSG |
| monooxygenase activity | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2C19, CYP17A1, CYP2E1, CYP11A1, CYP1A2, CYP26A1, CYP1A1, CYP1B1, CYP24A1 |
| monovalent inorganic cation transmembrane transporter activity | molecular_function | ATP1B4 |
| morphine receptor activity | molecular_function | OPRM1 |
| morphogen activity | molecular_function | GREM1, WNT1, NODAL |
| mRNA 3'-UTR AU-rich region binding | molecular_function | ELAVL1 |
| mRNA 3'-UTR binding | molecular_function | ELAVL1 |
| mRNA binding | molecular_function | HSP90AA1, C1QBP, PARK7, ELAVL1, MBD2 |
| muramyl dipeptide binding | molecular_function | NOD2 |
| MutLalpha complex binding | molecular_function | MSH2, MSH6, PCNA |
| MutSalpha complex binding | molecular_function | MLH1, PMS2 |
| myosin binding | molecular_function | SLC6A4, VEZT, RHOA, CALD1 |
| myosin light chain binding | molecular_function | CXCR4 |
| N-acetylglucosamine 6-O-sulfotransferase activity | molecular_function | CHST6, CHST2 |
| N-acetyltransferase activity | molecular_function | KAT2B |
| N-formyl peptide receptor activity | molecular_function | FPR1 |
| N-methyltransferase activity | molecular_function | PEMT |
| NAD binding | molecular_function | HPGD, HSD11B2 |
| NAD+ ADP-ribosyltransferase activity | molecular_function | SIRT1 |
| NAD+ binding | molecular_function | HPGD, SIRT1 |
| NAD-dependent histone deacetylase activity | molecular_function | SIRT1 |
| NAD-dependent histone deacetylase activity (H3-K14 specific) | molecular_function | HDAC2, HDAC1 |
| NAD-dependent histone deacetylase activity (H3-K9 specific) | molecular_function | SIRT1 |
| NAD-dependent protein deacetylase activity | molecular_function | SIRT1 |
| NADH dehydrogenase (ubiquinone) activity | molecular_function | NDUFS1 |
| NADH dehydrogenase activity | molecular_function | NDUFS1 |
| NADP binding | molecular_function | NOS2, MTHFR, NOS3, CAT |
| NADP-retinol dehydrogenase activity | molecular_function | AKR1C3 |
| NADPH binding | molecular_function | SRD5A1 |
| natural killer cell lectin-like receptor binding | molecular_function | HLA-E, MICA, MICB, ULBP2 |
| nerve growth factor receptor binding | molecular_function | NGF |
| neuregulin binding | molecular_function | ITGA6, ERBB3, ITGB3, ITGAV |
| neuropeptide binding | molecular_function | OPRM1, SSTR1, SSTR5, KISS1R |
| neuropeptide hormone activity | molecular_function | CRH, UCN, NPY |
| neuropeptide receptor activity | molecular_function | KISS1R |
| neuropilin binding | molecular_function | VEGFA, SEMA3A, SEMA3C |
| neurotransmitter:sodium symporter activity | molecular_function | SLC6A4, SLC6A2 |
| neurotrophin binding | molecular_function | NTRK2 |
| neurotrophin p75 receptor binding | molecular_function | NTF4 |
| neurotrophin receptor activity | molecular_function | NTRK2 |
| neurotrophin TRKA receptor binding | molecular_function | PIK3R1, SHC1 |
| neurotrophin TRKB receptor binding | molecular_function | BDNF |
| NF-kappaB binding | molecular_function | GSK3B, APEX1, CDKN2A, ANXA4, HDAC2, RELA, HDAC1, FOXP3 |
| NFAT protein binding | molecular_function | PPARA, FOXP3 |
| nitric oxide binding | molecular_function | GSTP1 |
| nitric-oxide synthase activity | molecular_function | NOS2, NOS3 |
| nitric-oxide synthase binding | molecular_function | CTNNB1, SLC6A4, CD74, ACTB |
| nitric-oxide synthase regulator activity | molecular_function | AKT1, ESR1, HSP90AA1, EGFR |
| non-membrane spanning protein tyrosine kinase activity | molecular_function | SRC, JAK1, TYK2, FYN, PTK2 |
| non-membrane spanning protein tyrosine phosphatase activity | molecular_function | ACP1 |
| norepinephrine:sodium symporter activity | molecular_function | SLC6A2 |
| Notch binding | molecular_function | NOTCH1, ADAM17, JAG1, DLL4 |
| nuclear export signal receptor activity | molecular_function | CSE1L |
| nuclear hormone receptor binding | molecular_function | CTNNB1, ACTN4, HIF1A, SIRT1 |
| nuclear localization sequence binding | molecular_function | IPO13 |
| nuclease activity | molecular_function | APEX1, ANG, DICER1, PMS2, ISG20 |
| nucleic acid binding | molecular_function | EGR1, BCL6, ATF2, TIA1, WT1, ZEB1, ANG, KLF11, SNAI1, MSI1, KHDRBS3, PRDM1, YBX1, DICER1, ELAVL1, FOXP3, ZNF366, KLF10, KLF9, PPRC1, RBM43, CHD5, ISG20 |
| nucleic acid binding transcription factor activity | molecular_function | GATA3 |
| nucleoside binding | molecular_function | ACTN4, PNP |
| nucleoside diphosphate kinase activity | molecular_function | NME1 |
| nucleosomal DNA binding | molecular_function | HMGA2, HDAC2, ACTB, HDAC1, MBD2 |
| nucleosome binding | molecular_function | ARID1A |
| nucleotide binding | molecular_function | GCLC, GSK3B, MSH2, MSH6, HSPD1, ATP5A1, FGFR1, SRC, MET, MAPK1, FGFR2, CFTR, KIT, AKT1, ERBB3, NME1, CLCN3, KDR, FLT4, HSPA6, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, TIA1, PIK3CA, FLT3, MTOR, MAT2A, HSPA4, MKI67, CHEK2, XRCC3, AURKA, ATP5B, INSR, HSP90AA1, EGFR, RHOC, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, ABCC4, MSI1, KALRN, DIRAS3, PAK4, NRAS, KRAS, CSF1R, ABCB1, CDC42, RAC1, PLK1, PTK2, DICER1, NTRK2, TYRO3, ACTB, TEK, PAK1, ACLY, NOD2, ATP7A, ELAVL1, MST1R, ATM, NOD1, LIMK1, DAPK1, PIM2, AMHR2, ABCG2, TRPV1, RND3, Sep-09, PPRC1, RBM43, CHD5, ATAD3A, FHIT, RHOA, RERG |
| nucleotidyltransferase activity | molecular_function | TERT, GALT |
| O-methyltransferase activity | molecular_function | COMT |
| oligosaccharide binding | molecular_function | SELP, SELE |
| oligosaccharyl transferase activity | molecular_function | DAD1 |
| omega peptidase activity | molecular_function | UCHL1 |
| oncostatin-M receptor activity | molecular_function | IL6ST, LIFR |
| opioid receptor activity | molecular_function | OPRM1 |
| opsonin binding | molecular_function | ITGAV |
| organic anion transmembrane transporter activity | molecular_function | SLC22A23 |
| ornithine decarboxylase activator activity | molecular_function | PRLR |
| oxalate transmembrane transporter activity | molecular_function | SLC26A8 |
| oxidized purine DNA binding | molecular_function | MSH2, MSH6, OGG1 |
| oxidized purine nucleobase lesion DNA N-glycosylase activity | molecular_function | OGG1 |
| oxidoreductase activity | molecular_function | XDH, AKR1B1, NDUFS1, AKR1D1, NOS2, PRDX6, APEX1, ALOX15, GPX3, CYP19A1, HPGD, MTHFR, CYP2A6, HMOX1, HSD3B2, HSD17B1, IDO1, CYP2B6, MAOA, LPO, PTGS1, NOS3, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, HSD17B2, AKR1C3, ALDH3A2, AKR1C2, CYP17A1, MT-CO2, CYP2E1, CYP11A1, SOD1, CYP1A2, CYP26A1, CP, GPX1, CAT, CYP1A1, MPO, ADI1, LOXL4, AKR1C1, HSD17B7, HSD11B2, LOXL1, CYP1B1, TET3, SRD5A1, CYP24A1, TET2, TET1 |
| oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | molecular_function | TXN |
| oxidoreductase activity, acting on CH-OH group of donors | molecular_function | XDH |
| oxidoreductase activity, acting on diphenols and related substances as donors | molecular_function | CYP1A1 |
| oxidoreductase activity, acting on NAD(P)H | molecular_function | NDUFS1 |
| oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2C19, CYP17A1, CYP2E1, CYP11A1, CYP1A2, CYP26A1, CYP1A1, CYP1B1, CYP24A1 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | molecular_function | TET3, TET2, TET1 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | molecular_function | CYP2E1, CYP11A1 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2E1, CYP1A2, CYP1A1, CYP1B1 |
| oxidoreductase activity, acting on peroxide as acceptor | molecular_function | CAT, PARK7 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | molecular_function | ALOX15, PTGS2 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | molecular_function | XDH |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | molecular_function | ALDH3A2 |
| oxidoreductase activity, acting on the CH-CH group of donors | molecular_function | SRD5A2, SRD5A1 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | molecular_function | LOXL4, LOXL1 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | molecular_function | HSD3B2 |
| oxygen binding | molecular_function | CYP19A1, CYP2B6, CYP2C19, CYP17A1, CYP2E1, CYP1A2, CYP26A1, CYP1A1, CYP1B1 |
| oxytocin receptor activity | molecular_function | OXTR |
| p53 binding | molecular_function | GSK3B, HSPD1, MUC1, TP53, SIRT1, EHMT2, CDKN2A, TP63 |
| patched binding | molecular_function | CCNB1, IHH |
| PDZ domain binding | molecular_function | GJA1, CFTR, CLCN3, PTEN, ADAM17, CADM1, MUC17 |
| peptidase activator activity | molecular_function | FBLN1, MMP14, FN1 |
| peptidase activity | molecular_function | MME, MMP13, MMP9, CASP1, ACE, CASP3, UCHL1, MMP7, MMP10, MMP14, CMA1, MMP11, MMP12, PLAT, LTF, CAPN5, CTSB, PLAU, MMP1, CTSD, KLK3, MMP2, MMP3, CTSG, COPS5, PARK7, ADAM17, PCSK5, ADAM8, BLMH, TPSAB1, FOLH1, PAPPA, IHH, HTRA1, CPB2, MMP24, TPSB2 |
| peptidase inhibitor activity | molecular_function | TIMP2, TIMP3, A2M, SERPINA1, NGF, TIMP1, BIRC5, SLPI, SERPINE1, SPINK1, SERPINB2, WFDC2, TIMP4 |
| peptide alpha-N-acetyltransferase activity | molecular_function | NAA15 |
| peptide antigen binding | molecular_function | HLA-DRB1, HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, HLA-B, HLA-DQA1, HLA-DPB1, HLA-DRA |
| peptide binding | molecular_function | MME, CRHBP, CMA1, OXTR, ITGB1, ANG, CTSB, PCSK5 |
| peptide disulfide oxidoreductase activity | molecular_function | TXN |
| peptide hormone binding | molecular_function | INHBA, ANXA5, AGTR2, PRLR, OXTR, CRHR2 |
| peptide hormone receptor binding | molecular_function | LEP, FYN |
| peptidoglycan binding | molecular_function | TLR2, NOD2, NOD1 |
| peptidyl-dipeptidase activity | molecular_function | ACE |
| peptidyl-prolyl cis-trans isomerase activity | molecular_function | FKBP4, FKBP5 |
| peroxidase activity | molecular_function | PRDX6, GPX3, LPO, PTGS1, PTGS2, GPX1, CAT, MPO |
| peroxiredoxin activity | molecular_function | PRDX6, PARK7 |
| peroxisome proliferator activated receptor binding | molecular_function | HMGA1, ESR2, NR0B2 |
| phenanthrene 9,10-monooxygenase activity | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
| phenylpyruvate tautomerase activity | molecular_function | MIF |
| phosphatase activity | molecular_function | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR |
| phosphatase binding | molecular_function | MAPK1, SMAD3, SMAD2, PPARA |
| phosphate ion binding | molecular_function | PNP, RELA |
| phosphatidic acid binding | molecular_function | PLCD1 |
| phosphatidyl-N-dimethylethanolamine N-methyltransferase activity | molecular_function | PEMT |
| phosphatidyl-N-methylethanolamine N-methyltransferase activity | molecular_function | PEMT |
| phosphatidylcholine 1-acylhydrolase activity | molecular_function | PLA2G4A, LIPC, PLA2G16 |
| phosphatidylcholine binding | molecular_function | CETP, APOA1, APOA2 |
| phosphatidylcholine-sterol O-acyltransferase activator activity | molecular_function | APOA1, APOA2, APOE |
| phosphatidylethanolamine binding | molecular_function | PEMT |
| phosphatidylethanolamine N-methyltransferase activity | molecular_function | PEMT |
| phosphatidylinositol 3-kinase activity | molecular_function | PIK3CA |
| phosphatidylinositol 3-kinase binding | molecular_function | PIK3R1, INSR, IGF1R, FYN, TYRO3, IRS2 |
| phosphatidylinositol 3-kinase regulator activity | molecular_function | PIK3R1 |
| phosphatidylinositol 3-kinase regulatory subunit binding | molecular_function | PIK3R1, ESR1 |
| phosphatidylinositol phosphate binding | molecular_function | PLCD1 |
| phosphatidylinositol phospholipase C activity | molecular_function | CCL5, PLCD1, CCR1, CCR5, EDNRA, PLCB1, PLCB3, PLCD3 |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | molecular_function | PTEN |
| phosphatidylinositol-3,4,5-trisphosphate binding | molecular_function | AKT1 |
| phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | molecular_function | PTEN |
| phosphatidylinositol-3,4-bisphosphate binding | molecular_function | AKT1 |
| phosphatidylinositol-3-phosphatase activity | molecular_function | PTEN |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | molecular_function | FGFR1, FGF2, FGFR2, PIK3R1, KIT, ERBB3, PDGFRA, KITLG, PIK3CA, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, NRG1, IRS2 |
| phosphatidylinositol-4,5-bisphosphate binding | molecular_function | ALOX15, ANXA2, PLCB1 |
| phosphatidylserine 1-acylhydrolase activity | molecular_function | PLA2G16 |
| phosphatidylserine binding | molecular_function | HMGB1, PLCD1, AXL, THBS1, GAS6, SCARB1 |
| phosphodiesterase I activity | molecular_function | APEX1 |
| phosphoglucomutase activity | molecular_function | PGM1 |
| phospholipase A2 activator activity | molecular_function | CASP3 |
| phospholipase A2 activity | molecular_function | PLA2G4A, PLA2G2A, RARRES3, PLA2G16, PAFAH1B2 |
| phospholipase A2 inhibitor activity | molecular_function | ANXA1, ANXA2 |
| phospholipase activator activity | molecular_function | CCL5, CCL3 |
| phospholipase activity | molecular_function | PLA2G4A, LIPC |
| phospholipase binding | molecular_function | SELE |
| phospholipase C activity | molecular_function | PLCD1, PLCB3 |
| phospholipase D activity | molecular_function | HMOX1 |
| phospholipase inhibitor activity | molecular_function | ANXA5, ANXA4, ANXA1, ANXA2 |
| phospholipid binding | molecular_function | F3, ANXA5, SHC1, PLA2G2A, PON1, ANXA1, APOA1, APOA2, APOE, NR5A2, NR5A1, LPAR3 |
| phospholipid transporter activity | molecular_function | CETP, APOA1 |
| phosphoprotein binding | molecular_function | SRC, IGF2R, SHC1, MTOR, PLAT, RB1, FKBP4, TRPV1 |
| phosphoprotein phosphatase activity | molecular_function | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR, ILKAP |
| phosphopyruvate hydratase activity | molecular_function | ENO2, ENO1 |
| phosphoric diester hydrolase activity | molecular_function | APEX1, PLCD1, PLCB1, PLCB3, PLCD3 |
| phosphorylase activity | molecular_function | TYMP |
| phosphotyrosine binding | molecular_function | MAPK1, SHC1 |
| placental growth factor-activated receptor activity | molecular_function | FLT1 |
| platelet-activating factor acetyltransferase activity | molecular_function | PAFAH1B2 |
| platelet-derived growth factor alpha-receptor activity | molecular_function | PDGFRA |
| platelet-derived growth factor binding | molecular_function | PDGFRA, PDGFA, COL4A1 |
| platelet-derived growth factor receptor binding | molecular_function | VEGFA, PDGFRA, IL1R1, TYMP, ITGB3, PDGFA, FIGF, PTEN |
| poly(A) binding | molecular_function | TIA1 |
| poly(A) RNA binding | molecular_function | HSPD1, ATP5A1, TXN, HMGB1, LGALS3, APEX1, NME1, CDKN2A, CTNNA1, STIP1, LGALS1, TIA1, MKI67, HSP90AA1, JUN, ACTN4, HSPB1, ENO1, MSI1, ANXA2, KHDRBS3, C4BPA, YBX1, HDAC2, EIF3E, FKBP4, POU5F1, ELAVL1, NAA15, PPRC1, DCN |
| poly(U) RNA binding | molecular_function | MSI1 |
| potassium channel regulator activity | molecular_function | DPP6, DRD2, SGK1, PIAS3 |
| pre-miRNA binding | molecular_function | DICER1 |
| prenylated protein tyrosine phosphatase activity | molecular_function | PTP4A3 |
| primary amine oxidase activity | molecular_function | VCAM1, MAOA |
| prolactin receptor activity | molecular_function | PRLR |
| prolactin receptor binding | molecular_function | PRL |
| proline-rich region binding | molecular_function | YAP1, CCND1 |
| promoter-specific chromatin binding | molecular_function | DNMT1, EZH2, EHMT2 |
| prostaglandin D2 11-ketoreductase activity | molecular_function | AKR1C3 |
| prostaglandin E receptor activity | molecular_function | HPGD, PTGER4, PTGER3, PTGER2 |
| prostaglandin F receptor activity | molecular_function | PTGFR |
| prostaglandin H2 endoperoxidase reductase activity | molecular_function | AKR1C3 |
| prostaglandin receptor activity | molecular_function | PPARG, PTGER4, PTGER3 |
| prostaglandin transmembrane transporter activity | molecular_function | SLCO2A1 |
| prostaglandin-D synthase activity | molecular_function | PTGDS |
| prostaglandin-E synthase activity | molecular_function | PTGES, PTGES2 |
| prostaglandin-endoperoxide synthase activity | molecular_function | PTGS1, PTGS2 |
| prostaglandin-F synthase activity | molecular_function | AKR1C3 |
| protease binding | molecular_function | BCL2, ITGA3, F3, KIT, CASP3, BRCA2, IL1R1, FAS, TIMP2, TIMP3, FN1, ITGB3, ITGB1, ITGAV, A2M, SERPINA1, TIMP1, TP53, TNF, ANXA2, SERPINE1, TIMP4 |
| proteasome binding | molecular_function | ID1 |
| protein anchor | molecular_function | PDCD6 |
| protein antigen binding | molecular_function | KLRC1, KLRD1 |
| protein binding | molecular_function | GSK3B, MSH2, MSH6, H2AFX, MLH1, CRK, BCL2, HSPD1, NDUFS1, PGM1, ATP5A1, FGFR1, EGR1, SRC, TXN, CDH1, GATA3, ITGA6, INHBA, YAP1, FGF2, CCND1, VEGFA, FSHR, MET, BCL6, STAT3, NOS2, NR2F2, BMP4, CRHR1, DNMT1, PCNA, CDX1, CD40LG, F2R, WNT5A, MME, HMGA2, ITGA3, PTGDS, PPARG, TNFRSF1A, PRDX6, CCL5, FBLN1, MAPK1, FGFR2, IGF2R, HMGB1, LGALS3, IGFBP2, CLU, GJA1, CFTR, IGFBP3, APEX1, PIK3R1, CD36, ALOX15, F3, GPX3, IL10, KIT, IL12B, VIM, MMP9, CXCL8, OPRM1, MIF, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, ATF2, EPCAM, CFL1, BRCA1, PTGER4, CCL3, SERPINF1, SLC6A4, NFKB1, HMGA1, CASP1, AR, TOB1, KRT19, WNT2, MBL2, TNFSF10, AHR, ERBB3, CDKN1B, NOTCH1, NME1, ACE, DRD2, CLCN3, KDR, ID1, FPR1, CASP3, RASSF2, FASLG, SPP1, CSF1, SDC4, CCR1, CCR5, FLT4, UCHL1, CDKN1A, CSF2RB, HSPA6, CDKN2A, VDR, TNFRSF1B, CD40, BRAF, XRCC1, MUC1, CTNNA1, STIP1, PDGFRA, AXL, AGTR1, AGTR2, ANXA4, ENG, PRLR, COL4A2, BRCA2, FST, HLA-DRB1, S100P, JAK1, IGFBP5, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, CRHBP, GATA2, LAMA1, SPARC, TYK2, LGALS1, HGF, FLT1, KRT7, CNTF, ENO |
| protein binding involved in protein folding | molecular_function | CD74 |
| protein binding, bridging | molecular_function | CRK, ANXA1, FGA, FKBP4 |
| protein C-terminus binding | molecular_function | MSH2, SRC, YAP1, FBLN1, VIM, OPRM1, CTNNB1, ID1, STIP1, SDC1, MKI67, ERBB2, MAP2K7, XRCC4, SIRT1, KSR1, PIAS3 |
| protein channel activity | molecular_function | MCL1 |
| protein complex binding | molecular_function | FGFR1, SRC, CCND1, FBLN1, APEX1, SHC1, CTNNB1, EPCAM, MTHFR, KRT19, CDKN1B, CASP3, CDKN1A, ITGA2, FAS, HNF1B, FLT3, ESR1, INSR, ITGB1, ACTN4, MYC, FYN, CTSB, ITGB2, NRAS, KRAS, ICAM1, RELA, HIF1A, BAX, PPARA, KAT2B, ATM, NR0B2 |
| protein deacetylase activity | molecular_function | HDAC2, HDAC1, SIRT1 |
| protein dimerization activity | molecular_function | GATA3, STAT3, AR, AHR, ID1, USF1, ARNT, CLOCK, MYC, ERBB2, PDCD6, HPSE, HIF1A, HES5, HEY1, ID2, ATM, TWIST1, ABCG2, USF2, AHRR |
| protein disulfide isomerase activity | molecular_function | ITGB3 |
| protein disulfide oxidoreductase activity | molecular_function | TXN, PTGES2 |
| protein domain specific binding | molecular_function | CRK, SRC, DNMT1, WNT5A, ITGA3, GJA1, OPRM1, MTOR, INSR, ITGB1, IL1B, WNT1, DICER1, PLAUR, NFE2L2, PPARA, SIRT1, YWHAH, TWIST1, NR0B2, TP63, IRS2, MBD2 |
| protein heterodimerization activity | molecular_function | GCLC, H2AFX, BCL2, INHBA, VEGFA, ITGA3, PIK3R1, IL12B, ATF2, NFKB1, AHR, ERBB3, NOTCH1, DRD2, CLCN3, BRAF, AXL, AGTR1, ITGA2, HGF, USF1, LIFR, HNF1B, BMP6, ARNT, IL12A, ITGB1, EGFR, JUN, TGFB1, INHA, TP53, APOA2, PDGFA, BIRC5, TLR2, ENO1, ERBB2, MEIS1, SOX15, FOS, CXCL13, ITGB2, TGFB2, SMAD3, RELA, BCL2L1, HIF1A, TYRO3, BAX, SMAD2, MCL1, NECTIN1, SMAD4, LIMK1, HIST3H3, YWHAH, TWIST1, NECTIN3, HIST2H3A, USF2, PAFAH1B2, NOTCH4, ADIPOR2, ADIPOR1 |
| protein homodimerization activity | molecular_function | MSH2, MSH6, XDH, BCL2, FGFR1, VEGFA, NOS2, NR2F2, BMP4, CCL5, FGFR2, KIT, IL12B, HPGD, SLC6A4, NFKB1, ERBB3, DRD2, CLCN3, ID1, CSF1, PDGFRA, ENG, PRLR, IL6R, IL6ST, LGALS1, GSTM1, HMOX1, USF1, HLA-G, HNF1B, PON1, FLT3, PTGS2, CCR2, CHEK2, GSTZ1, HSP90AA1, JUN, ANG, CRYAB, TGFB1, ACTN4, ANXA1, SOD1, S100A6, APOA2, APOE, TERT, PDGFA, BIRC5, CD4, PDCD6, FIGF, AGR2, CAT, CSF1R, TGFB2, SMAD3, RELA, BCL2L1, PARK7, NTRK2, BAX, PLCB1, S100A13, SMAD2, ADIPOQ, MCL1, ELAVL1, NECTIN1, FOXP3, NOD1, SMAD4, TWIST1, NECTIN3, CADM1, SCARB1, NR0B2, ABCG2, USF2, PAFAH1B2, NECTIN4, OLFM4, CADM2, IL17F, KLRK1, LILRB1 |
| protein kinase A catalytic subunit binding | molecular_function | GSK3B |
| protein kinase activator activity | molecular_function | HMGB1, PIK3CA |
| protein kinase activity | molecular_function | GSK3B, FGFR1, SRC, CCND1, MET, CCL5, MAPK1, FGFR2, KIT, AKT1, CCL3, ERBB3, KDR, RASSF2, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, CCL2, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, PLK1, PTK2, NTRK2, TYRO3, TEK, PAK1, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2, KSR1 |
| protein kinase binding | molecular_function | GSK3B, MSH2, SRC, CCND1, STAT3, MAPK1, AKT1, CTNNB1, CCNB1, ATF2, NME1, CDKN2A, USF1, MTOR, CCR2, CHEK2, AURKA, INSR, ITGB1, HSP90AA1, TP53, HSPB1, CD4, LATS1, MAP2K7, SPRY2, ITGB2, CDC42, RAC1, PTEN, PLK1, PTK2, SMAD3, RELA, BCL2L1, HIF1A, DPYSL2, PAK1, NOD2, KAT2B, ELAVL1, ERRFI1, GATA6, IRS2, PTPRR, ADIPOR1 |
| protein kinase C activity | molecular_function | PRKCB |
| protein kinase C binding | molecular_function | SRC, AKT1, SDC4, ITGAV, PRKCB, HSPB1, C1QBP |
| protein kinase C inhibitor activity | molecular_function | HSPB1 |
| protein kinase inhibitor activity | molecular_function | BGN, CDKN1B, CDKN1A, SOCS3, DCN |
| protein N-terminus binding | molecular_function | CLU, ID1, TGFB1, ACTN4, TP53, SUV39H1, RELA, EIF3E, HDAC1, ATM, STX5, DCN, PIAS3 |
| protein phosphatase 1 binding | molecular_function | LILRB1 |
| protein phosphatase 2A binding | molecular_function | BCL2, AKT1, SHC1, TP53, FOXO1, EIF4EBP1 |
| protein phosphatase 2B binding | molecular_function | SOD1 |
| protein phosphatase binding | molecular_function | BCL2, MET, STAT3, PPARG, PIK3R1, CTNNB1, CDKN1B, FLT4, JAK1, STAT6, INSR, HSP90AA1, EGFR, TP53, ERBB2, MAP2K7, CSF1R, IRS2 |
| protein phosphatase inhibitor activity | molecular_function | PTN, SET |
| protein phosphorylated amino acid binding | molecular_function | CRK |
| protein self-association | molecular_function | CCL5, ID1, TP53, CTSB, SYP, FOXP1, ADAM8 |
| protein serine/threonine kinase activator activity | molecular_function | TGFB1, LTF, SPRY2, IGF2 |
| protein serine/threonine kinase activity | molecular_function | GSK3B, MAPK1, AKT1, BRAF, PIK3CA, MTOR, CHEK2, AURKA, MAP3K7, PRKCB, LATS1, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, PLK1, PAK1, ATM, LIMK1, DAPK1, PIM2, AMHR2 |
| protein serine/threonine kinase inhibitor activity | molecular_function | SPRY2 |
| protein serine/threonine phosphatase activity | molecular_function | PTEN, ILKAP |
| protein serine/threonine/tyrosine kinase activity | molecular_function | AKT1, AURKA, SGK1 |
| protein transmembrane transporter activity | molecular_function | AZGP1 |
| protein transporter activity | molecular_function | IPO13 |
| protein tyrosine kinase activator activity | molecular_function | ERBB3, NRG1, GAS6, GHRL |
| protein tyrosine kinase activity | molecular_function | FGFR1, SRC, FGF2, MET, FGFR2, KIT, ERBB3, KDR, FLT4, CSF2RB, PDGFRA, AXL, JAK1, TYK2, FLT1, FLT3, INSR, HSP90AA1, EGFR, FGF1, IGF1R, ERBB2, FYN, MAP2K7, EGF, CSF2, IL5, CSF1R, PTK2, NRG1, NTRK2, TYRO3, TEK, MST1R |
| protein tyrosine kinase binding | molecular_function | CD4 |
| protein tyrosine phosphatase activator activity | molecular_function | IGFBP3 |
| protein tyrosine phosphatase activity | molecular_function | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR |
| protein tyrosine/serine/threonine phosphatase activity | molecular_function | PTP4A3, PTEN, DUSP2 |
| protein tyrosine/threonine phosphatase activity | molecular_function | DUSP2 |
| protein xylosyltransferase activity | molecular_function | XYLT2 |
| protein-hormone receptor activity | molecular_function | FSHR, LHCGR |
| protein-lysine N-methyltransferase activity | molecular_function | EZH2, EHMT2 |
| proteoglycan binding | molecular_function | PTN, THBS1, CTSB |
| proton-transporting ATP synthase activity, rotational mechanism | molecular_function | ATP5A1, ATP5B |
| proton-transporting ATPase activity, rotational mechanism | molecular_function | ATP5A1, ATP5B |
| PTB domain binding | molecular_function | INSR |
| purine nucleobase binding | molecular_function | PNP |
| purine nucleoside binding | molecular_function | ADA |
| purine-nucleoside phosphorylase activity | molecular_function | PNP |
| purine-specific mismatch base pair DNA N-glycosylase activity | molecular_function | PCNA |
| purinergic nucleotide receptor activity | molecular_function | P2RX3 |
| pyrimidine-nucleoside phosphorylase activity | molecular_function | TYMP |
| R-SMAD binding | molecular_function | JUN, FOS, SMAD3, SMAD2, SMAD4 |
| Rab GTPase binding | molecular_function | SLC6A4, ANXA2, RAC1 |
| Rac GTPase binding | molecular_function | SOD1 |
| RAGE receptor binding | molecular_function | HMGB1, FPR1, S100P, S100A13 |
| Ran GTPase binding | molecular_function | BIRC5, CSE1L, IPO13 |
| Ras guanyl-nucleotide exchange factor activity | molecular_function | FGFR1, FGF2, FGFR2, KIT, SHC1, ERBB3, CSF2RB, PDGFRA, JAK1, KITLG, NCAM1, IL2RB, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, IL2RA, CSF2, IL5, PTK2, NRG1, TEK, IRS2, IL2, ANGPT1 |
| receptor activator activity | molecular_function | ANXA2, IGF2 |
| receptor activity | molecular_function | FOLR1, IGF2R, NOTCH1, FPR1, CXCR3, CSF2RB, CD40, ITGB5, FAS, ITGB6, MRC1, KIR2DL1, KIR2DL3, ITGB3, ITGB1, TLR2, TLR4, CD4, TNFRSF11B, TLR3, NRP2, ITGB2, KRT1, ICAM1, PLAUR, TEK, F2RL1, PPARA, NECTIN1, AGER, NECTIN3, CADM1, AMHR2, IL10RB, NECTIN4, NOTCH4, CADM2, KLRK1, ADIPOR2, ADIPOR1 |
| receptor agonist activity | molecular_function | VEGFA, WNT5A, WNT2, GREM1, WNT7A, CXCL13, WNT1, GAS6, WNT4, NODAL |
| receptor antagonist activity | molecular_function | AGTR2, DKK1, ESR2 |
| receptor binding | molecular_function | SRC, INHBA, FGF2, NOS2, F2R, WNT5A, IGFBP2, GJA1, LEP, MIF, AR, WNT2, MBL2, TNFSF10, DRD2, FASLG, JAK1, LAMA1, IGFBP1, CXCL1, TDGF1, CCL2, HLA-E, LIF, HLA-G, EFNA1, IGFBP4, BDNF, NTF4, ADM, CXCL12, ITGB1, FGF1, ANG, ANXA1, A2M, FGA, PLAT, INHA, NGF, CXCL10, C3, FYN, WNT7A, MSTN, ANGPT2, LAMA5, SERPINE1, PGR, IL1B, C5, LHB, LTA, HLA-B, AMH, CAT, WNT1, IL6, EDN1, CRH, TGFB2, PTK2, NRG1, PARK7, GAS6, PLAUR, F2RL1, STOML2, ADIPOQ, RARRES2, NECTIN1, TNFSF13B, NECTIN3, CADM1, CX3CL1, WNT4, HAMP, ANGPT1, NECTIN4, CADM2, IL27, CCL17, NPY, UCN2 |
| receptor signaling protein tyrosine kinase activator activity | molecular_function | CCL5 |
| receptor tyrosine kinase binding | molecular_function | PCNA, ANXA5, SHC1, TOB1, TP53, ANGPT2, NRG1, NTRK2, GAS6, ANGPT1, MST1 |
| receptor tyrosine kinase-like orphan receptor binding | molecular_function | WNT5A |
| recombinase activity | molecular_function | XRCC3 |
| regulatory region DNA binding | molecular_function | HMGA2, NFKB1, EZH2 |
| repressing transcription factor binding | molecular_function | HMGB1, CTNNB1, MYC, RELA, PARK7, HDAC1 |
| retinal binding | molecular_function | RBP1 |
| retinal dehydrogenase activity | molecular_function | AKR1C3 |
| retinoic acid 4-hydroxylase activity | molecular_function | CYP26A1 |
| retinoic acid binding | molecular_function | NR2F2, IGF2R, CYP26A1 |
| retinoic acid receptor binding | molecular_function | HMGA1, ACTN4, NR0B2 |
| retinoid binding | molecular_function | PTGDS, RBP1 |
| retinoid X receptor binding | molecular_function | PPARG, HMGA1, VDR, NR0B2 |
| retinol binding | molecular_function | RBP1 |
| retinol dehydrogenase activity | molecular_function | AKR1C3 |
| Rho GDP-dissociation inhibitor binding | molecular_function | HSP90AA1, CDC42, RAC1 |
| Rho guanyl-nucleotide exchange factor activity | molecular_function | KALRN |
| ribonuclease activity | molecular_function | AZGP1, ANG |
| ribonuclease III activity | molecular_function | DICER1 |
| ribonucleoprotein complex binding | molecular_function | EZH2 |
| ribosomal small subunit binding | molecular_function | NME1 |
| ribosome binding | molecular_function | MTOR, NAA15 |
| RNA binding | molecular_function | DNMT1, APEX1, BRCA1, TIA1, WT1, TERT, ENO1, TLR3, NR3C1, MSI1, ANXA2, KHDRBS3, YBX1, DICER1, PARK7, ELAVL1, EZH2, RPL41, PPRC1, RBM43, ISG20 |
| RNA polymerase I core binding | molecular_function | ERBB2 |
| RNA polymerase II activating transcription factor binding | molecular_function | CTNNB1, ATF2, JUN, RB1, SMAD3, NFE2L2 |
| RNA polymerase II carboxy-terminal domain kinase activity | molecular_function | MAPK1 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | molecular_function | STAT3, AR, MUC1, HOXA10, ESR1, JUN, CLOCK, MYC, MEIS1, NR5A2, FOS, NR3C1, PRDM1, PGR, YBX1, HDAC2, SMAD3, RELA, FOXL2, ACTB, HSF1, SMAD2, PPARA, NFKB2, HDAC1, SMAD4, DLX5, MBD2 |
| RNA polymerase II core promoter sequence-specific DNA binding | molecular_function | GATA3, YAP1, GATA2, STAT6, FOS, HSF1, GATA6 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | molecular_function | CDX1, ATF2, NFKB1, GATA2, JUN, NR5A2, HDAC2, RELA, ACTB, NR5A1, NFE2L2, HDAC1, MBD2 |
| RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | molecular_function | HSF1 |
| RNA polymerase II regulatory region sequence-specific DNA binding | molecular_function | EGR1, GATA3, BCL6, ATF2, NFKB1, NME1, GATA2, ACTN4, SNAI1, RUNX3, SMAD3, RELA, KAT2B, STAT4, SMAD4, GATA6, GATA5 |
| RNA polymerase II repressing transcription factor binding | molecular_function | STAT3, HDAC2, PPARA, HDAC1, GATA6 |
| RNA polymerase II transcription cofactor activity | molecular_function | PPRC1 |
| RNA polymerase II transcription corepressor activity | molecular_function | HDAC1 |
| RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | molecular_function | ESR1, ESR2 |
| RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | molecular_function | STAT3, NR2F2, PPARG, AR, AHR, VDR, PTGER3, ESR1, NR5A2, NR5A1, ESR2, PPARA |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | molecular_function | STAT3, JUN, TP53, SOX15, KLF11, RUNX3, FOXL2, HIF1A, FOXP1, FOXO1, POU5F1, FOXP3, TWIST1, GATA6 |
| RNA polymerase II transcription factor binding | molecular_function | GSK3B, GATA3, CTNNB1, AR, GATA2, TP53, HDAC1, SMAD4, GATA6, GATA5 |
| RNA polymerase III type 1 promoter DNA binding | molecular_function | MTOR |
| RNA polymerase III type 2 promoter DNA binding | molecular_function | MTOR |
| RNA polymerase III type 3 promoter DNA binding | molecular_function | MTOR |
| RNA-directed 5'-3' RNA polymerase activity | molecular_function | TERT |
| RNA-directed DNA polymerase activity | molecular_function | TERT |
| RNA-DNA hybrid ribonuclease activity | molecular_function | APEX1 |
| Roundabout binding | molecular_function | TGFB1I1 |
| rRNA binding | molecular_function | ANG |
| S-adenosylmethionine-dependent methyltransferase activity | molecular_function | SUV39H1, PEMT |
| S-nitrosoglutathione binding | molecular_function | GSTP1 |
| S100 protein binding | molecular_function | FGF1, S100A6, ANXA2, AGER |
| satellite DNA binding | molecular_function | MBD2 |
| scaffold protein binding | molecular_function | SRC, GJA1, VIM, NOS3, MAP3K7, PARK7 |
| scavenger receptor activity | molecular_function | LOXL4, CXCL16 |
| secondary active sulfate transmembrane transporter activity | molecular_function | SLC26A8 |
| selenium binding | molecular_function | GPX3 |
| semaphorin receptor activity | molecular_function | NRP1, NRP2 |
| semaphorin receptor binding | molecular_function | SEMA3A, SEMA3C |
| sequence-specific DNA binding | molecular_function | BCL2, EGR1, GATA3, BCL6, STAT3, NR2F2, CDX1, PPARG, ATF2, NFKB1, AR, NOTCH1, VDR, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ESR1, JUN, CLOCK, TP53, MEIS1, NR5A2, SNAI1, FOS, NR3C1, PRDM1, PGR, HDAC2, SMAD3, RELA, FOXL2, HIF1A, FOXP1, FOXO1, NR5A1, HSF1, NFE2L2, ESR2, PPARA, POU5F1, FOXP3, EZH2, SMAD4, TP63, EMX2, GATA6, USF2, DLX5, NANOG, GATA5, MAF, CREB3L1 |
| serine-type endopeptidase activity | molecular_function | MMP13, MMP9, MBL2, HGF, MMP7, MMP10, C4A, MMP14, CMA1, MMP11, MMP12, PLAT, LTF, C3, CTSB, PLAU, MMP1, CTSD, KLK3, MMP2, MMP3, CTSG, PCSK5, ADAM8, TPSAB1, HTRA1, TPSB2, MST1 |
| serine-type endopeptidase inhibitor activity | molecular_function | SERPINF1, SERPINA6, A2M, SERPINA1, SLPI, SERPINE1, SPINK1, SERPINB2, WFDC2 |
| serine-type peptidase activity | molecular_function | DPP6, CMA1, PLAT, LTF, PLAU, KLK3, CTSG, PCSK5, TPSAB1, HTRA1, TPSB2 |
| serotonin binding | molecular_function | MAOA |
| serotonin transmembrane transporter activity | molecular_function | SLC6A4 |
| serotonin:sodium symporter activity | molecular_function | SLC6A4 |
| SH2 domain binding | molecular_function | CRK, SRC, SYP, PTK2, LILRB1 |
| SH3 domain binding | molecular_function | GJA1, KHDRBS3, GPX1, ERRFI1, PTPN22, ADAM17 |
| SH3/SH2 adaptor activity | molecular_function | CRK, SRC, TOB1, GRB14 |
| sialic acid binding | molecular_function | SELP, SELE, ADIPOQ |
| signal transducer activity | molecular_function | FSHR, STAT3, CRHR1, F2R, GJA1, OPRM1, CTNNB1, PTGER4, DRD2, FPR1, PLCD1, CCR1, CCR5, CXCR3, CD40, AGTR1, AGTR2, FST, EDNRA, LGALS1, HMOX1, IL1R1, CXCR1, CXCR2, FAS, STMN1, STAT6, TACR2, TACR1, LHCGR, OXTR, SSTR1, SSTR5, CCR2, PTGFR, PTGER3, PTGER2, CCR9, EGFR, RHOC, LGR5, LGALS9, CXCR6, DKK1, PTK2, PLCB1, CXCR4, F2RL1, GPER1, IRS2, PLCB3, KISS1R, CRHR2, IL11RA, PLCD3, HRH4, IL1RAP, LPAR3, CCR7, CCR8, RXFP1 |
| signal transducer activity, downstream of receptor | molecular_function | BRAF, NCR1, IL1RL1 |
| signal transducer, downstream of receptor, with protein tyrosine kinase activity | molecular_function | KIT, KDR, INSR, EGFR, ERBB2, TYRO3 |
| signal transducer, downstream of receptor, with serine/threonine kinase activity | molecular_function | BMPR1B, MAP2K7, PAK4, TGFB2, PAK1, AMHR2 |
| signaling pattern recognition receptor activity | molecular_function | TLR2 |
| single base insertion or deletion binding | molecular_function | PMS2 |
| single guanine insertion binding | molecular_function | MSH2, MSH6 |
| single thymine insertion binding | molecular_function | MSH2, MSH6 |
| single-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular_function | ISG20 |
| single-stranded DNA binding | molecular_function | MSH2, MLH1, HSPD1, HMGB1, NME1, BRCA2, XRCC3, ANXA1, YBX1, PARK7, PMS2 |
| single-stranded RNA binding | molecular_function | HMGB1, ANXA1, MSI1 |
| siRNA binding | molecular_function | DICER1, TLR9, MBD2 |
| site-specific endodeoxyribonuclease activity, specific for altered base | molecular_function | APEX1 |
| SMAD binding | molecular_function | HMGA2, CTNNB1, TOB1, BMPR1B, COL5A2, SMAD3, SMAD2 |
| small GTPase binding | molecular_function | BRAF, ERRFI1 |
| small molecule binding | molecular_function | PTGDS, PAEP |
| small protein activating enzyme binding | molecular_function | PARK7 |
| SNAP receptor activity | molecular_function | STX5 |
| SNARE binding | molecular_function | STX5 |
| sodium channel regulator activity | molecular_function | SGK1, YWHAH |
| sodium-independent organic anion transmembrane transporter activity | molecular_function | SLCO2A1, SLCO4A1 |
| somatostatin receptor activity | molecular_function | SSTR1, SSTR5 |
| sphingomyelin phosphodiesterase activity | molecular_function | SMPD3 |
| sphingosine-1-phosphate phosphatase activity | molecular_function | SGPP2 |
| stem cell factor receptor activity | molecular_function | KIT |
| stem cell factor receptor binding | molecular_function | KITLG |
| steroid 17-alpha-monooxygenase activity | molecular_function | CYP17A1 |
| steroid binding | molecular_function | AKR1D1, AR, ESR1, IGF1, SERPINA6, PGRMC1, PGRMC2, NR3C1, PGR, SHBG, ESR2, GPER1, HSD11B2, SULT1E1 |
| steroid delta-isomerase activity | molecular_function | HSD3B2 |
| steroid hormone binding | molecular_function | NR3C1, ESR2, GPER1 |
| steroid hormone receptor activity | molecular_function | NR2F2, PPARG, VDR, ESR1, NR5A2, PGRMC2, NR3C1, PGR, NR5A1, ESR2, PPARA, GPER1, NR0B2 |
| steroid hydroxylase activity | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2C19, CYP2E1, CYP1A1 |
| steroid sulfotransferase activity | molecular_function | SULT1E1 |
| sterol 5-alpha reductase activity | molecular_function | SRD5A2 |
| steryl-sulfatase activity | molecular_function | STS |
| structural constituent of cytoskeleton | molecular_function | VIM, KRT19, ACTB |
| structural constituent of eye lens | molecular_function | VIM, CRYAB |
| structural constituent of muscle | molecular_function | KRT19 |
| structural constituent of ribosome | molecular_function | RPL41 |
| structural molecule activity | molecular_function | VIM, KRT19, CTNNA1, KRT7, MAP2, COL18A1, ANXA1, FGA, CLDN5, CLDN4, LAMA5, CLDN3, CLDN7, KRT1, JAG1 |
| structure-specific DNA binding | molecular_function | TET1 |
| substance K receptor activity | molecular_function | TACR2 |
| substance P receptor activity | molecular_function | TACR1 |
| sulfate transmembrane transporter activity | molecular_function | SLC26A8 |
| sulfonylurea receptor binding | molecular_function | HSP90AA1 |
| sulfotransferase activity | molecular_function | CHST6, CHST2, SULT1E1 |
| sulfuric ester hydrolase activity | molecular_function | STS, ARSH |
| SUMO transferase activity | molecular_function | CDKN2A, PIAS3 |
| supercoiled DNA binding | molecular_function | HMGB1 |
| superoxide dismutase activity | molecular_function | SOD1 |
| superoxide dismutase copper chaperone activity | molecular_function | PARK7, ATP7A |
| superoxide-generating NADPH oxidase activity | molecular_function | PAX2 |
| symporter activity | molecular_function | SLC6A4, SLC6A2 |
| syndecan binding | molecular_function | TNC, HPSE |
| syntaxin-1 binding | molecular_function | SLC6A4, DAPK1 |
| T cell receptor binding | molecular_function | FYN |
| tachykinin receptor activity | molecular_function | TACR2, TACR1 |
| TAP binding | molecular_function | HLA-A |
| Tat protein binding | molecular_function | ACTB, GABARAPL1 |
| tau protein binding | molecular_function | GSK3B, APOE, SGK1, FKBP4 |
| tau-protein kinase activity | molecular_function | GSK3B |
| telomerase activity | molecular_function | TERT |
| telomerase RNA binding | molecular_function | TERT |
| telomerase RNA reverse transcriptase activity | molecular_function | TERT |
| telomeric DNA binding | molecular_function | TERT |
| testosterone 17-beta-dehydrogenase (NADP+) activity | molecular_function | HSD17B3, AKR1C3 |
| testosterone dehydrogenase (NAD+) activity | molecular_function | HSD17B1, HSD17B3, HSD17B2, AKR1C3 |
| tetrahydrobiopterin binding | molecular_function | NOS2, NOS3 |
| tetrahydrofolyl-poly(glutamate) polymer binding | molecular_function | FOLH1 |
| TFIIIC-class transcription factor binding | molecular_function | MTOR |
| thiocyanate peroxidase activity | molecular_function | LPO |
| thioesterase binding | molecular_function | CDC42, RAC1 |
| thiol-dependent ubiquitin-specific protease activity | molecular_function | UCHL1, COPS5 |
| thiol-dependent ubiquitinyl hydrolase activity | molecular_function | UCHL1 |
| thrombin-activated receptor activity | molecular_function | F2R, F2RL1 |
| thrombospondin receptor activity | molecular_function | CD36, SDC4 |
| thymidine phosphorylase activity | molecular_function | TYMP |
| thyroid hormone receptor binding | molecular_function | NR0B2 |
| thyroid hormone transmembrane transporter activity | molecular_function | SLCO4A1 |
| Toll-like receptor binding | molecular_function | TLR2 |
| TPR domain binding | molecular_function | HSP90AA1 |
| trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
| transcription coactivator activity | molecular_function | GATA3, YAP1, APEX1, CTNNB1, ATF2, BRCA1, ARNT, ZEB1, PSMD9, JUN, RB1, ARID1A, TGFB1I1, COPS5, PARK7, NR5A1, ESR2, NFKB2, KAT2B, SRA1 |
| transcription coactivator binding | molecular_function | ESR1, TERT, FOXO1, PPARA |
| transcription cofactor activity | molecular_function | MUC1, NRG1, KAT2B |
| transcription cofactor binding | molecular_function | NFE2L2 |
| transcription corepressor activity | molecular_function | YAP1, CCND1, NR2F2, APEX1, TOB1, ZEB1, ENO1, C1QBP, FOXP3, SIRT1, DNMT3B, NR0B2, ZNF366, WNT4, NANOG |
| transcription factor activity, protein binding | molecular_function | SMAD3, HEY1, SMAD4 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular_function | EGR1, JUN, CLOCK, FOS |
| transcription factor activity, RNA polymerase II core promoter sequence-specific | molecular_function | SMAD3, HEY1 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | molecular_function | ATF2, USF1, HNF1B, ARNT, JUN, MEIS1, NR5A2, RELA, HIF1A, NR5A1, FOXP3, GATA6, USF2, GATA5 |
| transcription factor activity, RNA polymerase II transcription factor binding | molecular_function | YAP1, ATF2, HIF1A, SMAD4 |
| transcription factor activity, RNA polymerase II transcription factor recruiting | molecular_function | LIF |
| transcription factor activity, sequence-specific DNA binding | molecular_function | EGR1, GATA3, BCL6, STAT3, NR2F2, CDX1, WNT5A, PPARG, HMGB1, CTNNB1, ATF2, NFKB1, HMGA1, AR, AHR, NOTCH1, ID1, VDR, GATA2, USF1, HOXB2, STAT6, WT1, HNF1B, ARNT, SOX2, ZEB1, ESR1, JUN, CLOCK, TP53, MYC, ENO1, SMAD7, NR5A2, RB1, SOX15, KLF11, FOS, NR3C1, PRDM1, PGR, RUNX3, YBX1, SMAD3, RELA, FOXL2, HIF1A, FOXP1, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, NFKB2, POU5F1, HDAC1, FOXP3, STAT4, SMAD4, TWIST1, TP63, KLF10, GATA6, USF2, KLF9, TBPL2, NANOG, GATA5, TBX21, MAF, CREB3L1 |
| transcription factor activity, transcription factor binding | molecular_function | HMGA2, ARNT, HIF1A, FOXO1, TP63 |
| transcription factor binding | molecular_function | GSK3B, BCL2, GATA3, CCND1, STAT3, HMGA2, PPARG, MAPK1, HMGB1, PIK3R1, GPX3, CTNNB1, ATF2, NFKB1, HMGA1, AR, AHR, ID1, AGTR2, GATA2, ARNT, ZEB1, ESR1, JUN, TP53, MYC, RB1, FOS, PSMD10, C1QBP, HDAC2, SMAD3, RELA, PARK7, HIF1A, HES5, FOXO1, SMAD2, HEY1, POU5F1, KAT2B, HDAC1, SIRT1, TWIST1, NR0B2, CDKN2A, GATA6, PAX2, PPRC1 |
| transcription regulatory region DNA binding | molecular_function | EGR1, GATA3, YAP1, STAT3, CDX1, WNT5A, PPARG, CTNNB1, BRCA1, NFKB1, AR, AHR, WT1, HNF1B, SOX2, JUN, TP53, TNF, SMAD7, NR5A2, KLF11, FOS, WNT1, SMAD3, RELA, NFE2L2, POU5F1, HDAC1, SMAD4, TP63, GATA6, PAX2, DLX5, GATA5, TBX21, CREB3L1 |
| transcription regulatory region sequence-specific DNA binding | molecular_function | EGR1, GATA3, NFKB1, SOX2, SUV39H1, NR5A2, NR5A1, NFE2L2, POU5F1, HDAC1, SUV39H2 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular_function | EGR1, GATA3, STAT3, HMGA2, ATF2, AR, GATA2, HOXA10, WT1, SOX2, ESR1, JUN, MYC, MEIS1, NR5A2, FOS, NR3C1, PGR, YBX1, RELA, FOXL2, HIF1A, SMAD2, PPARA, NFKB2, SMAD4, TP63, DLX5, CREB3L1 |
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | molecular_function | CDX1, NFKB1, HMGA1, RELA, NFE2L2 |
| transcriptional activator activity, RNA polymerase II transcription factor binding | molecular_function | NOTCH1, JUN, CLOCK, PPARA |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular_function | GATA3, STAT3, ATF2, GATA2, TP53, HIF1A, SMAD4, GATA6, GATA5, MAF |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular_function | GATA3, HMGA2, SNAI1, PRDM1, RELA, HES5, FOXO1, HSF1, PPARA |
| transcriptional repressor activity, RNA polymerase II transcription factor binding | molecular_function | AHRR |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular_function | BCL6, NFKB1, ZEB1, SNAI1, FOXO1, POU5F1 |
| transferase activity | molecular_function | GSK3B, FGFR1, SRC, MET, DNMT1, MAPK1, FGFR2, KIT, AKT1, ATF2, ERBB3, NME1, KDR, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, GSTP1, GSTM1, NAT2, TYMP, PIK3CA, COMT, FLT3, MTOR, GSTT1, MAT2A, CHEK2, GSTZ1, AURKA, INSR, EGFR, CLOCK, MAP3K7, IGF1R, PRKCB, SUV39H1, TERT, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PRDM1, PAK4, PNP, CSF1R, GALT, PLK1, PTK2, DNMT3A, NTRK2, TYRO3, TEK, PAK1, ACLY, XYLT2, KAT2B, MST1R, EZH2, ATM, LIMK1, EHMT2, DAPK1, DNMT3B, PIM2, AMHR2, SUV39H2, DAD1, GBGT1, CHST6, CHST2, SULT1E1, PEMT |
| transferase activity, transferring acyl groups | molecular_function | LIPC, NAT2, CLOCK, KAT2B |
| transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | molecular_function | ACLY |
| transferase activity, transferring glycosyl groups | molecular_function | TYMP, PNP, XYLT2, DAD1, GBGT1 |
| transferase activity, transferring hexosyl groups | molecular_function | GBGT1 |
| transferase activity, transferring pentosyl groups | molecular_function | TYMP, PNP |
| transferrin receptor binding | molecular_function | TF |
| transforming growth factor beta binding | molecular_function | CD36, ENG, ITGAV, THBS1 |
| transforming growth factor beta receptor activity, type I | molecular_function | BMPR1B |
| transforming growth factor beta receptor activity, type II | molecular_function | AMHR2 |
| transforming growth factor beta receptor binding | molecular_function | INHBA, BMP4, BMP6, TGFB1, INHA, MSTN, GDF9, AMH, TGFB2, SMAD3, SMAD2, NODAL, GDF15 |
| transforming growth factor beta receptor, common-partner cytoplasmic mediator activity | molecular_function | SMAD4 |
| transforming growth factor beta receptor, cytoplasmic mediator activity | molecular_function | CDKN1B, ENG |
| transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity | molecular_function | SMAD7 |
| transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | molecular_function | SMAD3, SMAD2 |
| transforming growth factor beta-activated receptor activity | molecular_function | ENG |
| translation initiation factor activity | molecular_function | COPS5, EIF3E |
| translation initiation factor binding | molecular_function | EIF4EBP1 |
| translation repressor activity | molecular_function | EIF4EBP1 |
| transmembrane receptor protein serine/threonine kinase activity | molecular_function | BMPR1B, AMHR2 |
| transmembrane receptor protein tyrosine kinase activator activity | molecular_function | GREM1, EGF, NRG1 |
| transmembrane receptor protein tyrosine kinase activity | molecular_function | FGFR1, MET, FGFR2, KIT, KDR, FLT4, PDGFRA, AXL, FLT1, FLT3, INSR, EGFR, IGF1R, ERBB2, CSF1R, NTRK2, TYRO3, TEK, MST1R |
| transmembrane receptor protein tyrosine kinase adaptor activity | molecular_function | PIK3R1, SHC1 |
| transmembrane receptor protein tyrosine phosphatase activity | molecular_function | PTPRR |
| transmembrane signaling receptor activity | molecular_function | CRHR1, ERBB3, ENG, IL1R1, CD79A, FAS, LEPR, KLRC1, SELE, MRC1, FCER1G, EGFR, LGR5, TLR2, TLR4, ERBB2, CD4, CLDN4, TLR3, CLDN3, ICAM1, TLR9, AGER, KLRD1, TRPV1, CD69, CRHR2, IL11RA |
| transmembrane transporter activity | molecular_function | ATP5A1, GJA1, ATP5B, SLC22A23 |
| transporter activity | molecular_function | PTGDS, IGF2R, RBP1, AQP2, ATP5B, SLC22A23, AQP8, ABCB1, SYP, SCARB1, ABCG2, AQP5, SLCO2A1, SLCO4A1 |
| triacyl lipopeptide binding | molecular_function | TLR2 |
| triglyceride binding | molecular_function | CETP |
| triglyceride lipase activity | molecular_function | LIPC |
| tripeptidyl-peptidase activity | molecular_function | ACE |
| tRNA binding | molecular_function | TERT |
| tropomyosin binding | molecular_function | S100A6, TMOD3, CALD1 |
| tryptophan 2,3-dioxygenase activity | molecular_function | IDO1 |
| tubulin binding | molecular_function | BRCA1, MAP2, STMN1, BIRC5, FYN |
| tumor necrosis factor binding | molecular_function | TNFRSF1A, A2M |
| tumor necrosis factor receptor binding | molecular_function | CD40LG, TNFSF10, FASLG, TNF, LTA, TNFSF13B |
| tumor necrosis factor receptor superfamily binding | molecular_function | TNFSF10 |
| tumor necrosis factor-activated receptor activity | molecular_function | TNFRSF1A, TNFRSF1B, CD40, FAS, TNFRSF11B, TNFRSF21 |
| type 1 angiotensin receptor binding | molecular_function | TYK2 |
| type 1 metabotropic glutamate receptor binding | molecular_function | ESR1 |
| type I activin receptor binding | molecular_function | NODAL |
| type I transforming growth factor beta receptor binding | molecular_function | ENG, TGFB1, SMAD7, SMAD2 |
| type II activin receptor binding | molecular_function | INHBA |
| type II transforming growth factor beta receptor binding | molecular_function | ENG, TGFB1, TGFB2 |
| type III transforming growth factor beta receptor binding | molecular_function | TGFB1, TGFB2 |
| tyrosine 3-monooxygenase activator activity | molecular_function | PARK7 |
| U1 snRNA binding | molecular_function | ISG20 |
| U2 snRNA binding | molecular_function | ISG20 |
| U3 snoRNA binding | molecular_function | ISG20 |
| ubiquitin binding | molecular_function | UCHL1, HSPB1, SMAD3, CXCR4 |
| ubiquitin conjugating enzyme binding | molecular_function | FOXL2, PPARA |
| ubiquitin protein ligase activity | molecular_function | CDC42 |
| ubiquitin protein ligase binding | molecular_function | GSK3B, BCL2, HSPD1, PRDX6, CLU, BRCA1, UCHL1, CDKN1A, TNFRSF1B, CD40, JAK1, CHEK2, AURKA, EGFR, TP53, SMAD7, RB1, SMAD3, RELA, HIF1A, FOXO1, CXCR4, SMAD2, POU5F1, GABARAPL1, PTPN22, FHIT |
| ubiquitin-like protein conjugating enzyme binding | molecular_function | PARK7 |
| ubiquitin-protein transferase activity | molecular_function | BRCA1, BIRC5, TRIM36 |
| ubiquitin-protein transferase inhibitor activity | molecular_function | CDKN2A |
| ubiquitin-specific protease binding | molecular_function | PARK7 |
| UDP-glucose:hexose-1-phosphate uridylyltransferase activity | molecular_function | GALT |
| unfolded protein binding | molecular_function | HSPD1, HSPA6, HSP90AA1, CRYAB, APCS |
| unmethylated CpG binding | molecular_function | DNMT1, DNMT3A, DNMT3B |
| uracil DNA N-glycosylase activity | molecular_function | APEX1 |
| urokinase plasminogen activator receptor activity | molecular_function | PLAUR |
| UTP binding | molecular_function | HSP90AA1 |
| vascular endothelial growth factor binding | molecular_function | KDR, PDGFRA, PTN, NRP1 |
| vascular endothelial growth factor receptor 1 binding | molecular_function | VEGFA |
| vascular endothelial growth factor receptor 2 binding | molecular_function | VEGFA, GREM1, ITGB3 |
| vascular endothelial growth factor receptor 3 binding | molecular_function | VEGFC, FIGF |
| vascular endothelial growth factor receptor binding | molecular_function | VEGFA, FIGF |
| vascular endothelial growth factor-activated receptor activity | molecular_function | KDR, FLT4, PDGFRA, FLT1, FLT3, NRP1, NRP2 |
| vasopressin receptor activity | molecular_function | OXTR |
| VEGF-A-activated receptor activity | molecular_function | FLT1 |
| VEGF-B-activated receptor activity | molecular_function | FLT1 |
| very-low-density lipoprotein particle receptor binding | molecular_function | APOE |
| vinculin binding | molecular_function | CTNNA1 |
| virion binding | molecular_function | PTX3, CRP, APCS, NECTIN1 |
| virus receptor activity | molecular_function | CCR5, AXL, ITGA2, ITGB5, NCAM1, ITGB6, MRC1, ITGB3, ITGB1, ITGAV, CD4, ICAM1, TYRO3, CXCR4, NECTIN1, SCARB1, NECTIN4 |
| vitamin D 24-hydroxylase activity | molecular_function | CYP1A1 |
| vitamin D binding | molecular_function | GC |
| vitamin D response element binding | molecular_function | VDR |
| vitamin E binding | molecular_function | AFM |
| vitamin transporter activity | molecular_function | GC |
| voltage-gated calcium channel activity | molecular_function | OPRM1, ITGAV, GAS6 |
| voltage-gated chloride channel activity | molecular_function | CLCN3 |
| voltage-gated ion channel activity | molecular_function | CLCN3 |
| volume-sensitive chloride channel activity | molecular_function | CLCN3 |
| water channel activity | molecular_function | AQP2, AQP8, AQP5 |
| water transmembrane transporter activity | molecular_function | AQP2 |
| Wnt-activated receptor activity | molecular_function | EGF, SFRP4 |
| Wnt-protein binding | molecular_function | EGF, SFRP4 |
| WW domain binding | molecular_function | TP63 |
| xanthine dehydrogenase activity | molecular_function | XDH |
| xanthine oxidase activity | molecular_function | XDH |
| xenobiotic-transporting ATPase activity | molecular_function | ABCB1, ABCG2 |
| Y-form DNA binding | molecular_function | MSH2 |
| zinc ion binding | molecular_function | GATA3, NR2F2, DNMT1, MME, PPARG, MMP13, MMP9, BRCA1, AR, ACE, VDR, GATA2, MMP7, MMP10, MMP14, WT1, MMP11, ZEB1, MMP12, ESR1, CA2, SOD1, PRKCB, S100A6, TP53, SUV39H1, BIRC5, CD4, NR5A2, TGFB1I1, NR3C1, PGR, ADA, MMP1, GALT, MMP2, MMP3, SMAD3, S100A13, NR5A1, ESR2, PPARA, ADAM17, LIMK1, EHMT2, TRIM36, ADAM8, ADAM22, GATA6, SUV39H2, PAPPA, CHD5, CPB2, GATA5, MMP24, TET2, TET1, PIAS3 |