GO term name | GO category | Gene symbols |
---|
'de novo' pyrimidine nucleobase biosynthetic process | biological_process | MTOR |
3'-phosphoadenosine 5'-phosphosulfate metabolic process | biological_process | SULT1E1 |
3'-UTR-mediated mRNA stabilization | biological_process | ELAVL1 |
5-methylcytosine catabolic process | biological_process | TET2 |
5-methylcytosine metabolic process | biological_process | TET2 |
9-cis-retinoic acid biosynthetic process | biological_process | CYP1A1 |
acetaldehyde metabolic process | biological_process | RELA |
acetyl-CoA biosynthetic process | biological_process | ACLY |
acetyl-CoA metabolic process | biological_process | ACLY |
acid secretion | biological_process | DRD2 |
acrosome reaction | biological_process | TRIM36 |
actin cytoskeleton organization | biological_process | BCL6, SHC1, CFL1, CXCL1, PDGFA, KRAS, CDC42, RAC1, LIMK1, RND3, TMOD3, RHOA |
actin cytoskeleton reorganization | biological_process | KIT, SHC1, ANXA1, PAK1, RHOA |
actin filament branching | biological_process | CDC42 |
actin filament bundle assembly | biological_process | ACTN4, CDC42, AIF1 |
actin filament depolymerization | biological_process | CFL1 |
actin filament organization | biological_process | BCL2, CTNNA1, CDC42, RAC1, CRHR2, TMOD3, CCL11 |
actin filament polymerization | biological_process | ANG, RAC1, AIF1 |
actin filament-based process | biological_process | SELE |
actin polymerization or depolymerization | biological_process | GHRL |
activated T cell proliferation | biological_process | FYN, CADM1 |
activation of adenylate cyclase activity | biological_process | FSHR, CRHR1, EDNRA, LHCGR |
activation of blood coagulation via clotting cascade | biological_process | F3 |
activation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | XDH, HSPD1, F2R, PPARG, F3, CASP1, TNFSF10, CDKN1B, CASP3, FASLG, FAS, NGF, TNF, PDCD6, BCL2L11, SMAD3, BAX, NOD1, CDKN2A |
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | biological_process | CASP3, BAX |
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological_process | TNFSF10, FASLG, FAS, SMAD3, BAX |
activation of GTPase activity | biological_process | WNT5A, CCL21, CXCL13, CCR7 |
activation of innate immune response | biological_process | HMGB1, TLR4 |
activation of JAK2 kinase activity | biological_process | PRLR |
activation of JUN kinase activity | biological_process | CD40LG, WNT5A, MAP2K7, CCL19 |
activation of MAPK activity | biological_process | FGF2, WNT5A, MAPK1, KIT, SHC1, FPR1, HGF, SAA1, TDGF1, EFNA1, INSR, IGF1, FGF1, MAP3K7, SOD1, TNF, TLR4, THBS1, IL1B, EGF, C5, CD74, NRG1, CXCR4, NOD2, GHRL, NOD1, PROK1, LPAR3 |
activation of MAPK activity involved in innate immune response | biological_process | NOD2, ADAM8 |
activation of MAPKK activity | biological_process | CRK, BMP4, F2R, BRAF, FLT1, EGFR, MAP3K7, NGF, EGF, KISS1R |
activation of MAPKKK activity | biological_process | TNF |
activation of meiosis involved in egg activation | biological_process | PLCB1 |
activation of NF-kappaB-inducing kinase activity | biological_process | CHI3L1, MAP3K7, TLR3 |
activation of phospholipase A2 activity | biological_process | ANG |
activation of phospholipase A2 activity by calcium-mediated signaling | biological_process | EGFR |
activation of phospholipase C activity | biological_process | EDNRA, SELE, EGFR, ANG |
activation of phospholipase D activity | biological_process | CCL5 |
activation of plasma proteins involved in acute inflammatory response | biological_process | F3 |
activation of protein kinase A activity | biological_process | UCN |
activation of protein kinase activity | biological_process | VEGFA, HMGB1, DRD2, PIK3CA, INSR, ITGB3, TGFB2 |
activation of protein kinase B activity | biological_process | SRC, TXN, WNT5A, INSR, IGF1, FGF1, ANG, NRG1, PARK7, GAS6 |
activation of protein kinase C activity | biological_process | LEP |
activation of signaling protein activity involved in unfolded protein response | biological_process | BAX |
activation of transmembrane receptor protein tyrosine kinase activity | biological_process | PRLR, GREM1, EGF, NRG1, ANGPT1 |
activation-induced cell death of T cells | biological_process | AKT1, FAS, IL2RA |
active induction of host immune response by virus | biological_process | TGFB1 |
activin receptor signaling pathway | biological_process | INHBA, SMAD3, SMAD2 |
acute inflammatory response | biological_process | VCAM1, TACR1, APOA2, PTGES, DEFB1, OGG1 |
acute inflammatory response to antigenic stimulus | biological_process | OPRM1, ICAM1 |
acute-phase response | biological_process | STAT3, MBL2, IL6R, SAA1, IL1RN, FN1, FGA, SERPINA1, AHSG, CRP, HP, APCS, IL6, HIF1A, IL22 |
adaptive immune response | biological_process | HMGB1, CD79A, HLA-E, CTLA4, IFNG, ANXA1, FGA, PRKCB, CD4, FYN, TNFRSF21, CD74, C1QBP, MICA, IL2, MICB, CD1A, KLRK1, LILRB1 |
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological_process | TGFB1 |
adenohypophysis development | biological_process | DRD2, SOX2, GHRH |
adenosine catabolic process | biological_process | ADA |
adenosine metabolic process | biological_process | ADA |
adenylate cyclase-activating adrenergic receptor signaling pathway | biological_process | DRD2 |
adenylate cyclase-activating dopamine receptor signaling pathway | biological_process | OPRM1 |
adenylate cyclase-activating G-protein coupled receptor signaling pathway | biological_process | FSHR, LHCGR, PTGER2, GHRH, UCN2 |
adenylate cyclase-inhibiting dopamine receptor signaling pathway | biological_process | DRD2 |
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway | biological_process | HRH4 |
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | biological_process | OPRM1, SSTR5, PSAP |
adenylate cyclase-inhibiting opioid receptor signaling pathway | biological_process | OPRM1 |
adenylate cyclase-modulating G-protein coupled receptor signaling pathway | biological_process | PTGER4, DRD2, FPR1, CRHR2, RXFP1 |
adherens junction assembly | biological_process | CTNNB1, SMAD7 |
adherens junction organization | biological_process | SRC, CDH1, CTNNB1, CTNNA1, CDH3, ANG, CDC42, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
adhesion of symbiont to host | biological_process | ICAM1, SCARB1 |
adiponectin-activated signaling pathway | biological_process | ADIPOQ, ADIPOR2, ADIPOR1 |
adipose tissue development | biological_process | LEP, ATF2, PIK3CA, ID2 |
adrenal cortex formation | biological_process | WT1 |
adrenal gland development | biological_process | WT1, MDK, INSR, CYP17A1, FSTL3, APOA1, CRH, NR5A1, WNT4 |
adult behavior | biological_process | DRD2, PCDH17, PTEN |
adult feeding behavior | biological_process | LEP, GHRL, NPY |
adult heart development | biological_process | GJA1 |
adult locomotory behavior | biological_process | NTF4, CXCL12, SNCG, PARK7, ID2, ADAM22 |
adult walking behavior | biological_process | DRD2, UCHL1 |
aerobic respiration | biological_process | CAT, UCN |
aggressive behavior | biological_process | TACR1 |
aging | biological_process | GSK3B, STAT3, DNMT1, PLA2G4A, CCL5, IGFBP2, CLU, APEX1, F3, IL10, AKT1, SHC1, SERPINF1, TNFRSF1B, CTNNA1, EDNRA, MMP7, FAS, CCL2, IL15, VCAM1, TIMP2, PTGS1, ADM, TIMP3, CCR2, IGF1, JUN, CRYAB, TGFB1, SOD1, TIMP1, SOCS3, FOS, IL1B, CP, ITGB2, ADA, AMH, CAT, CYP1A1, MPO, IL6, PTEN, RELA, DNMT3A, NTRK2, BAX, NFKB2, PAX2, CX3CL1, RETN, OGG1, DCN |
aldosterone secretion | biological_process | AGTR2 |
alkaloid metabolic process | biological_process | CYP1A2 |
alpha-beta T cell differentiation | biological_process | BRAF, ANXA1 |
ameboidal-type cell migration | biological_process | WNT5A |
amelogenesis | biological_process | ITGA6, ATF2 |
amine metabolic process | biological_process | VCAM1, CYP1A1 |
AMPA glutamate receptor clustering | biological_process | APOE |
amygdala development | biological_process | ESR2 |
amyloid fibril formation | biological_process | CD36 |
anaphase-promoting complex-dependent catabolic process | biological_process | CCNB1, PSMD9, AURKA, PSMD10, PLK1 |
anatomical structure arrangement | biological_process | RAC1 |
anatomical structure development | biological_process | WNT4 |
anatomical structure formation involved in morphogenesis | biological_process | GATA3, BMP4, TP63, DLX5, NODAL, GATA5 |
anatomical structure morphogenesis | biological_process | GATA3, F2R, HOXA11, FGF1, CYR61, RAC1, POU5F1, ERVW-1 |
anatomical structure regression | biological_process | BMP4 |
androgen biosynthetic process | biological_process | HSD3B2, SRD5A2, HSD17B3, CYP17A1, SCARB1, WNT4, SRD5A1 |
androgen metabolic process | biological_process | AKR1D1, CYP19A1, SRD5A2, ADM, ESR1, SRD5A1 |
androgen receptor signaling pathway | biological_process | CTNNB1, BRCA1, AR, RB1, ARID1A, TGFB1I1, FKBP4 |
angiogenesis | biological_process | FGFR1, FGF2, VEGFA, BMP4, FGFR2, LEP, CXCL8, SHC1, NOTCH1, KDR, ID1, PLCD1, FLT4, CXCR3, ENG, COL4A2, FLT1, HMOX1, LEPR, CCL2, MMP14, TYMP, EFNA1, PIK3CA, NOS3, PTGS2, VEGFC, COL18A1, FN1, ATP5B, GREM1, JUN, FGF1, ITGAV, ANG, PDGFA, PDCD6, MEIS1, WNT7A, NRP1, ANGPT2, LAMA5, ANXA2, SERPINE1, FIGF, NRP2, EGF, PLAU, COL4A1, MMP2, PTEN, TGFB2, PTK2, HIF1A, TEK, HEY1, IL18, SIRT1, ADAM8, NAA15, JAG1, DLL4, PROK1, ANGPT1, CYP1B1, PLCD3 |
angiogenesis involved in coronary vascular morphogenesis | biological_process | NRP1 |
angiogenesis involved in wound healing | biological_process | ITGB3, GPX1, HPSE, CX3CL1 |
angiotensin catabolic process in blood | biological_process | ACE |
angiotensin maturation | biological_process | MME, ACE, CMA1, CTSG |
angiotensin-activated signaling pathway | biological_process | AGTR1, AGTR2, CA2 |
angiotensin-activated signaling pathway involved in heart process | biological_process | SRC |
angiotensin-mediated drinking behavior | biological_process | TACR1 |
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure | biological_process | AGTR2 |
animal organ development | biological_process | CTNNB1, ZEB1, PAX2 |
animal organ formation | biological_process | GATA6 |
animal organ morphogenesis | biological_process | GSK3B, BCL2, GATA3, FGF2, CDX1, MAPK1, FGFR2, VDR, BRAF, ITGA2, GATA2, CCL2, VEGFC, COL18A1, INSR, GREM1, TNF, PDGFA, NRP1, LAMA5, RELA, TP63, JAG1, GATA5, DCN |
animal organ regeneration | biological_process | CCND1, PPARG, IGF2R, SHC1, NOTCH1, CDKN1A, HGF, GSTP1, CCL2, LIF, LIFR, FLT3, ADM, MKI67, CXCL12, TGFB1, APOA1, APOA2, SOCS3, ANGPT2, WNT1, GAS6, TEK, NR0B2 |
anion transmembrane transport | biological_process | ABCC4, SLC26A8 |
anion transport | biological_process | SLC26A8 |
anterior neural tube closure | biological_process | FOLR1 |
anterior/posterior axis specification | biological_process | BMP4, CDX1, CTNNB1, AURKA, NODAL |
anterior/posterior axis specification, embryo | biological_process | WNT5A, TDGF1 |
anterior/posterior pattern specification | biological_process | NR2F2, CDX1, WNT5A, HOXB2, HOXA10, HNF1B, HOXA11, SMAD2, SMAD4, PCSK5, EMX2, NODAL |
anterograde axonal transport | biological_process | SOD1 |
anti-Mullerian hormone signaling pathway | biological_process | AMHR2 |
antibacterial humoral response | biological_process | HLA-E, ADM, ANG, LTF, SLPI, DEFB1, NPY |
antibacterial peptide production | biological_process | KLK3 |
antifungal humoral response | biological_process | ADM, ANG, LTF, NPY |
antigen processing and presentation | biological_process | HLA-DRB1, HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, IFNG, HLA-B, HLA-DQA1, CD74, HLA-DPB1, MICA, MICB, ULBP2, HLA-DRA |
antigen processing and presentation of endogenous antigen | biological_process | CD74 |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent | biological_process | ABCB1 |
antigen processing and presentation of endogenous peptide antigen via MHC class Ib | biological_process | HLA-E |
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent | biological_process | ABCB1 |
antigen processing and presentation of exogenous peptide antigen via MHC class I | biological_process | FCER1G |
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological_process | CD36, ITGB5, HLA-C, HLA-E, HLA-G, HLA-A, PSMD9, ITGAV, PSMD10, HLA-B |
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | biological_process | HLA-C, HLA-E, HLA-G, HLA-A, HLA-B |
antigen processing and presentation of exogenous peptide antigen via MHC class II | biological_process | HLA-DRB1, FCER1G, HLA-DQA1, CD74, HLA-DPB1, CTSD, KIFAP3, HLA-DRA |
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent | biological_process | ABCB1 |
antigen processing and presentation of peptide antigen via MHC class I | biological_process | ACE, HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, HLA-B |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological_process | HLA-DRB1, HLA-DQA1, HLA-DPB1, HLA-DRA |
antigen processing and presentation, exogenous lipid antigen via MHC class Ib | biological_process | CD1A |
antral ovarian follicle growth | biological_process | ESR1 |
aorta development | biological_process | PRDM1, LOXL1 |
aorta morphogenesis | biological_process | JAG1 |
aortic valve morphogenesis | biological_process | GATA3, NOTCH1, EFNA1, TWIST1 |
apical junction assembly | biological_process | CTNNA1, RHOC, RHOA |
apolipoprotein A-I-mediated signaling pathway | biological_process | ITGB3, ITGAV, RHOA |
apoptotic cell clearance | biological_process | HMGB1, CD36, ALOX15, AXL, ITGAV, GAS6, TYRO3 |
apoptotic chromosome condensation | biological_process | GPER1 |
apoptotic DNA fragmentation | biological_process | HMGB1, CASP3, DICER1, FOXL2 |
apoptotic mitochondrial changes | biological_process | GCLC, BCL2, NDUFS1, AKT1, BCL2L1, BAX, MCL1, CDKN2A |
apoptotic process | biological_process | BCL2, TNFRSF1A, MAPK1, FGFR2, CLU, GJA1, IGFBP3, CHI3L1, AKT1, BRCA1, NFKB1, CASP1, TNFSF10, AHR, CASP3, FASLG, CXCR3, TNFRSF1B, LGALS1, TIA1, PAEP, HMOX1, G0S2, FAS, CHEK2, GREM1, IFNG, MAP3K7, PRKCB, IL1A, TP53, BIRC5, TLR2, PDCD6, SGK1, TNFRSF11B, RB1, KLF11, MAP2K7, NR3C1, BCL2L11, TNFRSF21, PSMD10, IL1B, PAK4, GPX1, ITGB2, LTA, IL2RA, C1QBP, PTEN, BCL2L1, FOXO1, BAX, CXCR4, PAK1, MCL1, SIRT1, ATM, NOD1, GPER1, DAPK1, PIM2, CADM1, IL24, CDKN2A, CSE1L, TP63, DAD1, SEMA3A, IL17A, FHIT, SRA1 |
apoptotic process in bone marrow | biological_process | BCL2L1 |
apoptotic process involved in blood vessel morphogenesis | biological_process | BAX |
apoptotic process involved in embryonic digit morphogenesis | biological_process | NOTCH1, BCL2L11, BAX |
apoptotic process involved in heart morphogenesis | biological_process | CYR61 |
apoptotic process involved in morphogenesis | biological_process | CRYAB |
apoptotic signaling pathway | biological_process | CASP3, FASLG, TNFRSF1B, CD40, FAS, TNF, TLR4, PDCD6, TNFRSF11B, TLR3, TNFRSF21, BAX, DAPK1 |
arachidonic acid metabolic process | biological_process | PLA2G4A, ALOX15, CYP1B1 |
arachidonic acid secretion | biological_process | PLA2G4A, ACE, DRD2, ANXA1, KISS1R |
arginine catabolic process | biological_process | NOS2, NOS3 |
arginine metabolic process | biological_process | ARG2 |
aromatic amino acid family metabolic process | biological_process | GSTZ1 |
aromatic compound catabolic process | biological_process | PON1, EPHX1 |
arterial endothelial cell differentiation | biological_process | NOTCH1, HEY1 |
artery morphogenesis | biological_process | VEGFA, ENG, APOE, SMAD7, NRP1, PRDM1 |
artery smooth muscle contraction | biological_process | EDNRA, EDN1 |
associative learning | biological_process | DRD2, TACR1, NPTX2, CRH, UCN |
astrocyte activation | biological_process | CNTF |
astrocyte cell migration | biological_process | CCL3, CCL2, MMP14 |
astrocyte development | biological_process | VIM, TLR4 |
astrocyte differentiation | biological_process | STAT3, NOTCH1, LIF, HES5 |
asymmetric protein localization | biological_process | WNT7A |
ATP biosynthetic process | biological_process | ATP5A1, ATP5B, TGFB1 |
ATP hydrolysis coupled proton transport | biological_process | ATP5A1, ATP5B |
ATP metabolic process | biological_process | NDUFS1, ATP5A1, ATP5B |
ATP synthesis coupled electron transport | biological_process | NDUFS1 |
ATP synthesis coupled proton transport | biological_process | ATP5A1, ATP5B |
ATP transport | biological_process | GJA1 |
ATP-dependent chromatin remodeling | biological_process | ARID1A, HDAC2, ACTB, HDAC1, MBD2 |
atrial cardiac muscle cell action potential | biological_process | GJA1 |
atrial cardiac muscle tissue morphogenesis | biological_process | WNT2 |
atrial septum morphogenesis | biological_process | CYR61 |
atrial ventricular junction remodeling | biological_process | GJA1 |
atrioventricular canal development | biological_process | SMAD4 |
atrioventricular node development | biological_process | NOTCH1 |
atrioventricular valve formation | biological_process | HEY1, SMAD4, OLFM1 |
atrioventricular valve morphogenesis | biological_process | NOTCH1, CYR61 |
attachment of GPI anchor to protein | biological_process | PLAUR |
auditory behavior | biological_process | DRD2 |
auditory receptor cell development | biological_process | FGFR1 |
auditory receptor cell differentiation | biological_process | HES5, JAG1 |
auditory receptor cell fate commitment | biological_process | NOTCH1 |
auditory receptor cell fate determination | biological_process | HES5 |
auditory receptor cell morphogenesis | biological_process | RAC1 |
auditory receptor cell stereocilium organization | biological_process | SOD1 |
autophagic cell death | biological_process | CDKN1B |
autophagosome assembly | biological_process | GABARAPL1 |
autophagy | biological_process | HMGB1, CTSB, CTSD, PARK7, FOXO1, GABARAPL1, PTPN22 |
axial mesodermal cell fate specification | biological_process | NODAL |
axis elongation | biological_process | WNT5A |
axon ensheathment | biological_process | NRG1 |
axon extension | biological_process | ITGB1 |
axon extension involved in axon guidance | biological_process | NRP1, NRP2, SEMA3A |
axon guidance | biological_process | GATA3, WNT5A, MAPK1, NCAM1, EFNA1, BDNF, L1CAM, CXCL12, FYN, NRP1, NRP2, NRAS, KRAS, CSF1R, RAC1, TGFB2, PTK2, DPYSL2, NECTIN1, SMAD4, DLX5, SEMA3A, SEMA3C, NTN4 |
axon regeneration | biological_process | BCL2, FOLR1, CTNNA1, JUN |
axon target recognition | biological_process | UCHL1 |
axonal fasciculation | biological_process | NRP1, SEMA3A |
axonal transport of mitochondrion | biological_process | UCHL1, HIF1A |
axonogenesis | biological_process | GSK3B, BCL2, WNT5A, FGFR2, NOTCH1, DRD2, UCHL1, STMN1, PRELP, S100A6, WNT7A, PAK1, TLR9, PAX2, DLX5 |
axonogenesis involved in innervation | biological_process | NRP1, SEMA3A |
B cell activation | biological_process | HSPD1, CD40, CD79A, PRKCB, IL4 |
B cell apoptotic process | biological_process | BCL2L11, TNFRSF21, BAX |
B cell chemotaxis | biological_process | CXCL13, GAS6 |
B cell chemotaxis across high endothelial venule | biological_process | CXCL13 |
B cell costimulation | biological_process | IL4 |
B cell cytokine production | biological_process | HSPD1 |
B cell differentiation | biological_process | MSH2, BCL2, BCL6, CD40LG, PIK3R1, IL10, CD79A, VCAM1, IL11, FLT3, ITGB1, IL4, ADAM17 |
B cell homeostasis | biological_process | BCL2, CASP3, BCL2L11, BAX, FOXP3 |
B cell homeostatic proliferation | biological_process | BAX |
B cell lineage commitment | biological_process | BCL2 |
B cell mediated immunity | biological_process | MSH2, FAS |
B cell negative selection | biological_process | BAX |
B cell proliferation | biological_process | BCL2, HSPD1, CD40LG, IL10, CD40, CD79A |
B cell proliferation involved in immune response | biological_process | TLR4 |
B cell receptor apoptotic signaling pathway | biological_process | BAX |
B cell receptor signaling pathway | biological_process | BCL2, MAPK1, CD79A, CTLA4, PRKCB |
B-1 B cell homeostasis | biological_process | HIF1A |
baculum development | biological_process | ESR1 |
base-excision repair | biological_process | HMGA2, HMGB1, APEX1, HMGA1, XRCC1, TP53, OGG1 |
base-excision repair, base-free sugar-phosphate removal | biological_process | APEX1 |
base-excision repair, DNA ligation | biological_process | XRCC1 |
basement membrane organization | biological_process | MMP11, COL4A1 |
basophil chemotaxis | biological_process | VEGFA |
behavior | biological_process | CCL3, NPY |
behavioral fear response | biological_process | BCL2, MDK, ESR2 |
behavioral response to cocaine | biological_process | DRD2 |
behavioral response to ethanol | biological_process | OPRM1, DRD2, CRHBP, HDAC2 |
behavioral response to formalin induced pain | biological_process | P2RX3 |
behavioral response to nicotine | biological_process | PPARA |
behavioral response to pain | biological_process | TACR1, THBS1, P2RX3 |
behavioral response to starvation | biological_process | SIRT1 |
benzene metabolic process | biological_process | CYP2E1 |
Bergmann glial cell differentiation | biological_process | MAPK1, VIM |
beta-amyloid metabolic process | biological_process | MME, ACE |
beta-catenin destruction complex assembly | biological_process | GSK3B |
beta-catenin destruction complex disassembly | biological_process | GSK3B, CTNNB1, WNT1 |
beta-catenin-TCF complex assembly | biological_process | CTNNB1, TERT, MYC, HDAC1 |
bicarbonate transport | biological_process | CFTR, CA2, SLC26A8 |
bicellular tight junction assembly | biological_process | ITGB1, ACTN4, CLDN3 |
bile acid and bile salt transport | biological_process | AKR1C1 |
bile acid biosynthetic process | biological_process | AKR1D1, STAR |
bile acid catabolic process | biological_process | AKR1D1 |
bile acid metabolic process | biological_process | LEP, NR5A2, AKR1C1 |
bile acid signaling pathway | biological_process | VDR |
binding of sperm to zona pellucida | biological_process | OVGP1 |
biological_process | biological_process | BGN, ABCC4, A1BG, NRM, NUDT6, IL22RA1, TIMP4, HRH4, RETN, MST1 |
biomineral tissue development | biological_process | SPP1 |
biphenyl metabolic process | biological_process | SRD5A2, STAR, CYP17A1 |
blastocyst development | biological_process | POU5F1, DAD1 |
bleb assembly | biological_process | LPAR3 |
blood circulation | biological_process | MTHFR, HOXB2, ADM, CXCL12, CXCL10, DLL4, NPY |
blood coagulation | biological_process | GATA3, F2R, CD36, F3, ANXA5, ITGA2, GATA2, FCER1G, ITGB3, FGA, SERPINA1, PLAT, C3, FYN, PLAU, CDC42, RAC1, HDAC2, GAS6, PLAUR, F2RL1, HDAC1, HIST2H3A, GATA6, P2RX3, CPB2, GATA5 |
blood coagulation, common pathway | biological_process | FGA |
blood coagulation, extrinsic pathway | biological_process | F3 |
blood coagulation, fibrin clot formation | biological_process | FBLN1, FGA |
blood coagulation, intrinsic pathway | biological_process | A2M, C1QBP |
blood vessel development | biological_process | BMP4, AHR, ITGAV, TGFB2, PTK2, HIF1A, FOXO1, ATP7A |
blood vessel endothelial cell migration | biological_process | ID1, APOA1, GPX1, SCARB1 |
blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological_process | BMP4 |
blood vessel lumenization | biological_process | DLL4 |
blood vessel maturation | biological_process | MMP2 |
blood vessel morphogenesis | biological_process | FGFR1, NR2F2, GJA1, ID1, FLT4, FLT1, MEIS1, ANGPT2, COL4A1, EDN1, HIF1A, CYP1B1 |
blood vessel remodeling | biological_process | BGN, ACE, AXL, AGTR2, LIF, NOS3, CCR2, TGFB2, BAX, ATP7A, JAG1, DLL4, SEMA3C |
BMP signaling pathway | biological_process | EGR1, BMP4, ID1, ENG, BMP6, BMPR1B, SMAD7, GDF9, SMAD4, DLX5, NODAL |
BMP signaling pathway involved in heart induction | biological_process | BMP4, POU5F1 |
BMP signaling pathway involved in nephric duct formation | biological_process | BMP4 |
BMP signaling pathway involved in renal system segmentation | biological_process | BMP4 |
BMP signaling pathway involved in ureter morphogenesis | biological_process | BMP4 |
body fluid secretion | biological_process | ANXA2, EDN1 |
bone development | biological_process | BMP4, FGFR2, PTGER4, SPARC, HSD17B1, MMP14, SRD5A2, WNT1, TWIST1, SRD5A1, STC1 |
bone growth | biological_process | LEP, LEPR |
bone mineralization | biological_process | MMP13, FGFR2, ALOX15, PTN, PTGS2, KLF10 |
bone mineralization involved in bone maturation | biological_process | LEP, IGF1 |
bone morphogenesis | biological_process | CDX1, MMP13, FGFR2, LTF, DLX5 |
bone regeneration | biological_process | POSTN |
bone remodeling | biological_process | RASSF2, IL6 |
bone resorption | biological_process | SRC, CTNNB1, RAC1 |
bone trabecula formation | biological_process | MMP2 |
brain development | biological_process | FGFR1, BMP4, DNMT1, BRCA1, SLC6A4, NOTCH1, ID1, AGTR2, BRCA2, FAS, STMN1, PTN, MTOR, STAR, CXCL12, BCL2L11, COL4A1, NRG1, HES5, DPYSL2, BAX, PLCB1, ATM, AGER, EMX2, IRS2, PAFAH1B2, NODAL |
brain morphogenesis | biological_process | SLC6A4, PTEN, PAX2 |
brain renin-angiotensin system | biological_process | AGTR2 |
brain-derived neurotrophic factor receptor signaling pathway | biological_process | BDNF, NTRK2 |
brainstem development | biological_process | SMAD4 |
branch elongation involved in mammary gland duct branching | biological_process | TGFB1 |
branch elongation involved in salivary gland morphogenesis | biological_process | FGFR2 |
branch elongation involved in ureteric bud branching | biological_process | FGF1 |
branching involved in blood vessel morphogenesis | biological_process | VEGFA, CTNNB1, ENG, EDNRA, NRP1, COL4A1, EDN1, DLL4, NOTCH4 |
branching involved in labyrinthine layer morphogenesis | biological_process | FGFR2, IL10, ADM, SOCS3 |
branching involved in mammary gland duct morphogenesis | biological_process | SRC, CSF1, CCL11 |
branching involved in prostate gland morphogenesis | biological_process | BMP4, FGFR2 |
branching involved in salivary gland morphogenesis | biological_process | FGFR1, FGFR2, LAMA5, IL6 |
branching involved in ureteric bud morphogenesis | biological_process | BCL2, FGF2, BMP4, CTNNB1, WT1, HOXA11, GREM1, MYC, LAMA5, WNT1, SMAD4, PAX2, WNT4 |
branching morphogenesis of a nerve | biological_process | FGFR2, DRD2 |
branching morphogenesis of an epithelial tube | biological_process | VEGFA, MET, BMP4, NOTCH1, MMP14, HNF1B, LAMA5, SPRY2, EGF, PAK1, WNT4 |
branchiomotor neuron axon guidance | biological_process | NRP1, SEMA3A |
bronchus development | biological_process | BMP4 |
brown fat cell differentiation | biological_process | ITGA6, PTGS2, ADIPOQ, RARRES2 |
bud dilation involved in lung branching | biological_process | BMP4 |
bud elongation involved in lung branching | biological_process | YAP1, BMP4, FGFR2, SPRY2 |
bud outgrowth involved in lung branching | biological_process | TNC |
bundle of His development | biological_process | ID2 |
C-5 methylation of cytosine | biological_process | DNMT1, DNMT3A, DNMT3B |
C-terminal protein deglutamylation | biological_process | FOLH1 |
C21-steroid hormone biosynthetic process | biological_process | AKR1B1, STAR, CYP11A1 |
C21-steroid hormone metabolic process | biological_process | AKR1D1, CYP11A1 |
calcium ion homeostasis | biological_process | ADM, AGER |
calcium ion transmembrane transport | biological_process | OPRM1, ANXA5, ITGAV, GAS6, TRPV1 |
calcium ion transport | biological_process | CCL5, CCL3, CCR1, CCR5, VDR, PRKCB, FYN, TRPV1, NPY |
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | biological_process | CLDN5, CLDN4, CLDN3, CLDN7 |
calcium-independent cell-matrix adhesion | biological_process | FN1, ITGB1 |
calcium-mediated signaling | biological_process | CXCL8, CCL3, CCR5, CXCR3, AGTR1, SELE, EDN1, CXCR4, KISS1R |
calcium-mediated signaling using intracellular calcium source | biological_process | KDR, VCAM1, SELP, PTGFR, NTRK2 |
camera-type eye development | biological_process | BMP4, WT1, CRYAB, BMPR1B, CYP1A1, HES5, JAG1, PAX2 |
camera-type eye morphogenesis | biological_process | VEGFA, BMP4, HIF1A, NECTIN1, AQP5 |
camera-type eye photoreceptor cell differentiation | biological_process | PROM1 |
cAMP biosynthetic process | biological_process | ADM, UCN2 |
cAMP-mediated signaling | biological_process | ADM, GHRH, KSR1 |
canonical glycolysis | biological_process | ENO2, ENO1 |
canonical Wnt signaling pathway | biological_process | GSK3B, CCND1, WNT5A, CTNNB1, WNT2, SDC1, CDH3, MYC, WNT7A, EGF, WNT1, CDC42, PTEN, WNT4 |
canonical Wnt signaling pathway involved in metanephric kidney development | biological_process | GATA3 |
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological_process | WNT1 |
canonical Wnt signaling pathway involved in negative regulation of apoptotic process | biological_process | CTNNB1, WNT1 |
canonical Wnt signaling pathway involved in positive regulation of apoptotic process | biological_process | GSK3B |
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation | biological_process | CTNNB1 |
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | biological_process | CTNNB1 |
carbohydrate catabolic process | biological_process | AMY2A |
carbohydrate metabolic process | biological_process | GSK3B, AKR1B1, PGM1, CHI3L1, AKT1, INSR, IGF2, AMY2A, GALT, HPSE, GBGT1, CHST6, CHST2, OVGP1 |
carbohydrate transport | biological_process | AKT1 |
carbon catabolite regulation of transcription | biological_process | USF1 |
carbon dioxide transport | biological_process | CA2, AQP5 |
carbon tetrachloride metabolic process | biological_process | CYP2E1 |
carboxylic acid catabolic process | biological_process | PON1 |
carboxylic acid metabolic process | biological_process | MIF |
cardiac atrium morphogenesis | biological_process | NOTCH1, DLL4 |
cardiac cell development | biological_process | MTOR |
cardiac cell fate determination | biological_process | POU5F1 |
cardiac chamber development | biological_process | ARID1A |
cardiac chamber formation | biological_process | NOTCH1 |
cardiac conduction | biological_process | GJA1 |
cardiac conduction system development | biological_process | CDC42, NRG1 |
cardiac epithelial to mesenchymal transition | biological_process | WNT2, NOTCH1, TGFB2, HEY1, OLFM1 |
cardiac left ventricle morphogenesis | biological_process | NOTCH1 |
cardiac muscle cell apoptotic process | biological_process | HSP90AA1 |
cardiac muscle cell development | biological_process | MTOR |
cardiac muscle cell differentiation | biological_process | ITGB1, ARID1A, NRG1, GATA6 |
cardiac muscle cell fate commitment | biological_process | WT1 |
cardiac muscle cell myoblast differentiation | biological_process | NRG1 |
cardiac muscle cell proliferation | biological_process | NOTCH1, TGFB2 |
cardiac muscle contraction | biological_process | PIK3CA, MTOR, CXCR4 |
cardiac muscle fiber development | biological_process | VEGFA |
cardiac muscle hypertrophy | biological_process | LEP, HDAC2 |
cardiac muscle hypertrophy in response to stress | biological_process | GATA6 |
cardiac muscle tissue development | biological_process | MTOR, ITGB1, PTEN, GATA6 |
cardiac muscle tissue morphogenesis | biological_process | NOTCH1 |
cardiac myofibril assembly | biological_process | PDGFRA |
cardiac neural crest cell development involved in heart development | biological_process | MAPK1 |
cardiac neural crest cell development involved in outflow tract morphogenesis | biological_process | TWIST1, JAG1 |
cardiac neural crest cell migration involved in outflow tract morphogenesis | biological_process | FOLR1, TWIST1 |
cardiac right atrium morphogenesis | biological_process | NOTCH1 |
cardiac right ventricle formation | biological_process | NOTCH1 |
cardiac right ventricle morphogenesis | biological_process | GATA3, JAG1, SEMA3C |
cardiac septum development | biological_process | BMP4, PRDM1, SMAD4, PCSK5 |
cardiac septum morphogenesis | biological_process | NOTCH1, HEY1, JAG1 |
cardiac vascular smooth muscle cell development | biological_process | VEGFA, NOTCH1 |
cardiac vascular smooth muscle cell differentiation | biological_process | GATA6 |
cardiac ventricle morphogenesis | biological_process | NOTCH1, HIF1A, HEY1, DLL4 |
cardioblast differentiation | biological_process | TGFB2 |
cardiolipin acyl-chain remodeling | biological_process | PLA2G4A |
cardiovascular system development | biological_process | APOE |
cartilage condensation | biological_process | BMPR1B, WNT7A, TGFB2 |
cartilage development | biological_process | BMP4, WNT5A, MMP13, CHI3L1, CD44, BMP6, ZEB1, TIMP1, BMPR1B, WNT7A, EDN1, HIF1A, HES5, GHRL, ATP7A, IHH, IL17F |
cartilage development involved in endochondral bone morphogenesis | biological_process | HOXA11 |
cartilage morphogenesis | biological_process | SNAI1 |
catagen | biological_process | TGFB2 |
catechol-containing compound metabolic process | biological_process | COMT |
catecholamine biosynthetic process | biological_process | CRHR2 |
catecholamine metabolic process | biological_process | MAOA, COMT, ATP7A |
catenin import into nucleus | biological_process | CTNNB1 |
cation transmembrane transport | biological_process | P2RX3 |
cation transport | biological_process | ATP7A, P2RX3 |
caveolin-mediated endocytosis | biological_process | MAPK1 |
CD4-positive, alpha-beta T cell activation | biological_process | STOML2 |
CD4-positive, alpha-beta T cell differentiation | biological_process | BRAF |
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | biological_process | FOXP3 |
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment | biological_process | FOXP3 |
CD8-positive, alpha-beta T cell activation | biological_process | HLA-E |
CD8-positive, alpha-beta T cell differentiation involved in immune response | biological_process | IFNG |
CD8-positive, alpha-beta T cell lineage commitment | biological_process | BCL2 |
cell activation | biological_process | GATA3, CCL3, PDGFRA, FN1, IGF1, TGFB1, TIMP1, PDGFA |
cell adhesion | biological_process | SRC, CDH1, ITGA6, ITGA3, CD36, CTNNB1, SPP1, CCR1, CXCR3, CTNNA1, ENG, ITGA2, ITGB5, LAMA1, CD44, KITLG, AZGP1, PECAM1, CCL2, NCAM1, VCAN, VCAM1, SELP, SELE, ITGB6, CDH3, TNC, L1CAM, COL18A1, CXCL12, FN1, ITGB3, ITGB1, ITGAV, CD4, CYR61, PCDH17, TGFB1I1, LAMA5, THBS1, NRP2, ITGB2, ADA, ICAM1, RAC1, HPSE, HES5, GAS6, TYRO3, NECTIN1, ADAM17, NECTIN3, CADM1, ADAM22, IGFBP7, RND3, CX3CL1, IL2, TRO, MUC16, LAMC2, POSTN, NECTIN4, CYP1B1, OLFM4, CADM2, MUC4, MMP24, LAMC1, CCL11, CCR8 |
cell adhesion mediated by integrin | biological_process | ITGA6, ITGA2, ICAM1, ADAM17 |
cell aging | biological_process | BCL2, MIF, BRCA2, MTOR, PRELP, SOD1, TP53, ICAM1, SIRT1, TP63 |
cell chemotaxis | biological_process | KIT, PDGFRA, AGTR1, ENG, HGF, CXCL1, VCAM1, CXCL2, CXCL5, CXCL12, CCL25, CCL21, CCL22, CXCL14, C5, CX3CL1, CXCL6, CCL27 |
cell communication | biological_process | GJA1, ANG, CCL16, NRG1, CCL19, JAG1, DLL4 |
cell communication by chemical coupling | biological_process | GJA1 |
cell communication by electrical coupling | biological_process | GJA1 |
cell communication by electrical coupling involved in cardiac conduction | biological_process | GJA1 |
cell cycle | biological_process | H2AFX, MLH1, SRC, CCND1, HMGA2, MAPK1, CCNB1, BRCA1, AHR, CDKN1B, RASSF2, CDKN1A, CDKN2A, BRCA2, MKI67, CHEK2, AURKA, TP53, SUV39H1, BIRC5, LATS1, RB1, NR3C1, PAK4, PLK1, KAT2B, ATM, GPER1, PIM2, SUV39H2, Sep-09, FSD1, RHOA, TET2, SMPD3 |
cell cycle arrest | biological_process | MSH2, INHBA, IL12B, CXCL8, CDKN1B, CDKN1A, CDKN2A, IL12A, MTOR, SOX2, IFNG, TGFB1, INHA, TP53, MYC, RB1, THBS1, TGFB2, SMAD3, GAS6, KAT2B, ATM, CAB39L, RPRM |
cell cycle checkpoint | biological_process | RB1 |
cell death | biological_process | CLU, CDKN1B, HMOX1, PTGER3, TGFB2, IL17A |
cell development | biological_process | INHBA, INHA, MSTN, GDF9, ID2, GATA6, GDF15, GATA5, MAF |
cell differentiation | biological_process | GSK3B, INHBA, FGF2, VEGFA, BMP4, CDX1, WNT5A, LGALS3, AKT1, CTNNB1, NOTCH1, NME1, KDR, SPP1, CSF1, BRAF, AXL, JAK1, GATA2, TYK2, FLT1, CNTF, TDGF1, STMN1, TYMP, MDK, BMP6, ARNT, FLT3, SRD5A2, L1CAM, VEGFC, ZEB1, FGF1, ANG, INHA, TP53, SUV39H1, FYN, BMPR1B, SOX15, NRP1, TGFB1I1, ANGPT2, LAMA5, FIGF, NRP2, AMH, PRM1, CDC42, FOXL2, NTRK2, HIF1A, HES5, FOXO1, DPYSL2, NR5A1, MCL1, RARRES2, SIRT1, TWIST1, GPER1, CADM1, TP63, NAA15, SLC26A8, SUV39H2, PAX2, WNT4, DLL4, ANGPT1, SEMA3A, SFRP4, NOTCH4, CHD5, SEMA3C, NANOG, SRD5A1, KLRK1, SRA1 |
cell differentiation in hindbrain | biological_process | GATA2 |
cell differentiation in spinal cord | biological_process | NOTCH1 |
cell differentiation involved in embryonic placenta development | biological_process | KRT19 |
cell division | biological_process | CCND1, HMGA2, CCNB1, CHEK2, AURKA, BIRC5, LATS1, RB1, NR3C1, PLK1, Sep-09, FSD1, RHOA |
cell fate commitment | biological_process | GATA3, BMP4, WNT5A, PPARG, FGFR2, WNT2, NOTCH1, CASP3, WNT7A, TGFB1I1, SPRY2, PRDM1, WNT1, SMAD2, GATA6, WNT4, NODAL, GATA5 |
cell fate commitment involved in formation of primary germ layer | biological_process | POU5F1 |
cell fate determination | biological_process | GATA3, CTNNB1, GATA2, MCL1, JAG1, PAX2, NOTCH4 |
cell fate specification | biological_process | CTNNB1, NOTCH1, ITGB1 |
cell growth | biological_process | BCL2, AR, MTOR, ITGB3, ITGAV, TGFB1, PAK4, IL6, EDN1, TGFB2, ATAD3A |
cell growth involved in cardiac muscle cell development | biological_process | AGTR2 |
cell junction assembly | biological_process | ACTB |
cell maturation | biological_process | FGFR1, GATA3, VEGFA, PPARG, CTNNB1, AXL, GATA2, IL15, CCL21, HES5, CCL19, ID2 |
cell migration | biological_process | GSK3B, FGFR1, SRC, WNT5A, IL12B, SDC4, ENG, JAK1, TYK2, FLT1, MMP14, SDC1, EFNA1, MDK, IL12A, ITGB3, ITGB1, ITGAV, ANG, TGFB1, FYN, SNAI1, NRP1, LAMA5, THBS1, PAK4, RAC1, PTEN, TGFB2, NRG1, GAS6, CXCR4, NODAL, LAMC1, RHOA |
cell migration involved in endocardial cushion formation | biological_process | NOTCH1, ENG |
cell migration involved in gastrulation | biological_process | NODAL |
cell migration involved in sprouting angiogenesis | biological_process | FGF2, VEGFA, KDR, TDGF1, GREM1, ITGB1, NRP1 |
cell morphogenesis | biological_process | BCL2, GATA3, YAP1, BCL6, CLU, VDR, HGF, GREM1, EGFR, TGFB2, NRG1, ADAM8 |
cell morphogenesis involved in differentiation | biological_process | CTNNB1, DKK1 |
cell morphogenesis involved in neuron differentiation | biological_process | RB1, ID2 |
cell motility | biological_process | ENG, RAC1, PTK2, ADAM17 |
cell projection assembly | biological_process | PDGFA |
cell projection organization | biological_process | AKT1, MTOR, AURKA |
cell proliferation | biological_process | BCL2, SRC, TXN, YAP1, MET, STAT3, PCNA, MIF, AKT1, CTNNB1, SERPINF1, AR, CSF1, UCHL1, BRCA2, EDNRA, ITGA2, HGF, CXCL1, KITLG, IGFBP4, ZEB1, MKI67, IGF1, EGFR, FGF1, TGFB1, IL1A, TP53, ERBB2, CYR61, LAMA5, FIGF, PAK4, GPX1, PRL, IL2RA, CD74, CYP1A1, CSF1R, RAC1, PTEN, PLK1, TGFB2, NRG1, BCL2L1, GAS6, BAX, TNFSF13B, SMAD4, PIM2, CSE1L, KLF10, IGSF8, IRS2, DLX5, ISG20, NANOG, NPY, UCN2, SRA1, PEMT |
cell proliferation in bone marrow | biological_process | ACE |
cell proliferation in forebrain | biological_process | WNT7A, EMX2 |
cell proliferation in midbrain | biological_process | WNT2, WNT1 |
cell proliferation involved in heart valve development | biological_process | TWIST1 |
cell recognition | biological_process | PECAM1, VCAN, LAMA5, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
cell redox homeostasis | biological_process | GCLC, TXN, NOS2, APEX1, NOS3, LTF, GPX1, IL6, NFE2L2, PTGES2 |
cell surface receptor signaling pathway | biological_process | INHBA, MET, CRHR1, TNFRSF1A, CD36, IL12B, MIF, TNFSF10, CCR1, CCR5, CXCR3, TNFRSF1B, AGTR2, PRLR, LAMA1, IL1R1, CXCR1, CXCR2, CD79A, LEPR, CCL2, KLRC1, LIFR, TACR2, TACR1, CD82, FCER1G, OXTR, SSTR1, BSG, EGFR, IFNG, ANXA1, INHA, CXCL10, ERBB2, CD4, CCL25, FYN, CXCL13, C5, PRL, IL2RA, EDN1, AGER, KLRD1, TRPV1, SST, CRHR2, IL17A |
cell-abiotic substrate adhesion | biological_process | ID1 |
cell-cell adhesion | biological_process | EPCAM, MMP24 |
cell-cell adhesion mediated by cadherin | biological_process | MMP24 |
cell-cell adhesion mediated by integrin | biological_process | ITGB1 |
cell-cell junction assembly | biological_process | CLDN5 |
cell-cell junction maintenance | biological_process | CSF1R |
cell-cell junction organization | biological_process | GJA1, TGFB1, RAC1, TGFB2, SMAD3 |
cell-cell signaling | biological_process | TXN, INHBA, CCL5, FGFR2, GJA1, IL10, CCL3, AR, WNT2, TNFSF10, FASLG, CCR1, CCR5, IL15, IL11, EFNA1, BDNF, SSTR1, SRD5A2, NTF4, IL13, ADM, CXCL5, GREM1, INHA, NGF, CXCL10, PDGFA, CCL21, CYR61, CCL22, NRP1, CCL16, CXCL13, PGR, IL1B, CXCL14, ITGB2, CGA, LHB, GHRH, LTA, AMH, WNT1, EDN1, TGFB2, NR5A1, TEK, ESR2, IL18, PCSK5, KLF10, CCL7, IL2, SST, CXCL6, IHH, IL17A, IL22, CCL17, GDF15, CCL27 |
cell-matrix adhesion | biological_process | ITGA6, ITGA3, CTNNB1, ITGA2, ITGB5, CD44, VCAM1, ITGB6, FN1, ITGB3, ITGB1, ITGAV, FGA, BCL2L11, ITGB2, RAC1, HPSE, MUC4 |
cell-substrate adhesion | biological_process | ITGA6, ITGA2, ITGB3, ITGB1, ITGAV, GAS6, ANGPT1 |
cell-substrate junction assembly | biological_process | ITGA6, FN1, ITGB3 |
cellular aldehyde metabolic process | biological_process | ALDH3A2 |
cellular amino acid biosynthetic process | biological_process | ADI1, FOLH1 |
cellular amino acid metabolic process | biological_process | MTHFR |
cellular aromatic compound metabolic process | biological_process | CYP1A2, EPHX1, CYP1B1 |
cellular biogenic amine metabolic process | biological_process | MAOA |
cellular calcium ion homeostasis | biological_process | BCL2, CCL5, CCL3, DRD2, CCR1, VDR, CD40, CCL2, CCR2, CXCL12, ITGB1, TGFB1, PRKCB, APOE, STOML2, CCL19, CCL7, CCL11, STC1 |
cellular chloride ion homeostasis | biological_process | FASLG |
cellular component disassembly involved in execution phase of apoptosis | biological_process | CASP3, PTK2 |
cellular copper ion homeostasis | biological_process | CCDC22, ATP7A |
cellular defense response | biological_process | CCR5, CXCR2, HLA-G, CCR2, CCR9, ITGB1, NCR1, IL4, RELA |
cellular detoxification of nitrogen compound | biological_process | GSTM1 |
cellular developmental process | biological_process | PRDM1 |
cellular extravasation | biological_process | TNF, ITGB2 |
cellular glucose homeostasis | biological_process | PIK3R1, FOXO1, SIRT1 |
cellular heat acclimation | biological_process | HSPA6 |
cellular homeostasis | biological_process | CCL2, CCR2, MCL1, MUC17 |
cellular hyperosmotic response | biological_process | ERRFI1 |
cellular iron ion homeostasis | biological_process | HMOX1, BMP6, HMOX2, SOD1, MYC, CP, TF, HPX, HIF1A, SMAD4, ABCG2, HAMP |
cellular ketone metabolic process | biological_process | CYP2B6 |
cellular lipid metabolic process | biological_process | STAR, PPARA |
cellular oxidant detoxification | biological_process | PRDX6, GPX3, LPO, PTGS1, GSTT1, PTGS2, GSTZ1, APOE, GPX1, HP, CAT, PARK7 |
cellular process | biological_process | CTNNB1, JUN |
cellular process regulating host cell cycle in response to virus | biological_process | BCL2L11, BCL2L1 |
cellular protein catabolic process | biological_process | CHEK2 |
cellular protein complex assembly | biological_process | CCL5, FGA, MBD2 |
cellular protein complex disassembly | biological_process | NRG1 |
cellular protein complex localization | biological_process | SMAD7 |
cellular protein localization | biological_process | WNT5A, CTNNB1, CTNNA1, TP53, LATS1, CDC42 |
cellular protein metabolic process | biological_process | MMP13, IGFBP2, IGFBP3, CSF2RB, IGFBP5, IGFBP1, SAA1, IGFBP4, IGF1, FGA, APOA1, LTF, PRL, IGF2, APCS, MMP1, KLK3, MMP2, CTSG, HIST2H3A, GATA6, PAPPA, SFTPA1 |
cellular protein modification process | biological_process | AKT1, PLAT |
cellular respiration | biological_process | NDUFS1, CYP1A2, BAX |
cellular response to alkaloid | biological_process | STAR, ICAM1, BCL2L1, TRPV1 |
cellular response to alkyl hydroperoxide | biological_process | CCL5 |
cellular response to amino acid starvation | biological_process | CDKN1A |
cellular response to amino acid stimulus | biological_process | DNMT1, CCL5, ZEB1, EGFR, TNF, COL4A1, COL5A2, MMP2, BCL2L1, DNMT3A, NTRK2 |
cellular response to antibiotic | biological_process | PLA2G4A, CDKN1B, STAR, CYP17A1, IL1B |
cellular response to arsenic-containing substance | biological_process | HMOX1 |
cellular response to ATP | biological_process | CCL2, PTGS2, SOD1, TRPV1 |
cellular response to bacterial lipopeptide | biological_process | CD36, TLR2 |
cellular response to bisphenol A | biological_process | CHEK2 |
cellular response to BMP stimulus | biological_process | GATA3, BMP4, BMP6, FN1, BMPR1B, SMAD4, GATA6, DLX5, GATA5 |
cellular response to brain-derived neurotrophic factor stimulus | biological_process | NFKB1, NTRK2 |
cellular response to cadmium ion | biological_process | HMOX1, AKR1C3, STAR, SOD1, CYP1A2, OGG1 |
cellular response to calcium ion | biological_process | WNT5A, ALOX15, BRAF, CRHBP, AKR1C3, JUN, FOS, EDN1 |
cellular response to cAMP | biological_process | CFTR, APEX1, IGFBP5, CRHBP, WT1, STAR, AQP8, ADIPOQ, SRD5A1, STC1 |
cellular response to carbohydrate stimulus | biological_process | NFKB1, PRKCB |
cellular response to carbon monoxide | biological_process | HIF1A |
cellular response to cell-matrix adhesion | biological_process | GSTP1 |
cellular response to cGMP | biological_process | SLC6A4 |
cellular response to cholesterol | biological_process | INHBA |
cellular response to cobalt ion | biological_process | SERPINF1, FAS, HIF1A |
cellular response to cocaine | biological_process | CRHBP, CRH |
cellular response to cold | biological_process | FOXO1 |
cellular response to copper ion | biological_process | AQP2 |
cellular response to corticosteroid stimulus | biological_process | AKR1C3 |
cellular response to corticotropin-releasing hormone stimulus | biological_process | CRHR1, CRHR2 |
cellular response to cortisol stimulus | biological_process | KLF9 |
cellular response to cyanide | biological_process | HIF1A |
cellular response to cytokine stimulus | biological_process | GATA3, STAT3, MME, CCL5, FAS, FLT3, IL13, FGA, CSF1R, CXCR4, CCR7 |
cellular response to decreased oxygen levels | biological_process | AKT1, PTEN |
cellular response to dexamethasone stimulus | biological_process | SERPINF1, AGTR2, CCL2, STAR, TGFB1, MSTN, IL6, CRH, FOXO1, ERRFI1, DNMT3B, ABCG2, SRD5A1 |
cellular response to diacyl bacterial lipopeptide | biological_process | CD36, TLR2 |
cellular response to diterpene | biological_process | NFKB1 |
cellular response to DNA damage stimulus | biological_process | MSH2, MSH6, H2AFX, MLH1, BCL2, YAP1, CCND1, BCL6, PCNA, MAPK1, HMGB1, APEX1, AKT1, ATF2, BRCA1, CASP3, CDKN1A, XRCC1, BRCA2, CTLA4, CHEK2, XRCC3, CLOCK, TP53, SUV39H1, MYC, SGK1, XRCC4, FOXO1, BAX, SIRT1, ATM, TP63, MICA, PMS2, OGG1 |
cellular response to dopamine | biological_process | GSK3B, ID1, HDAC2 |
cellular response to drug | biological_process | NOS2, NME1, BRAF, CRHBP, CCL2, CHEK2, TP53, MYC, TLR3, IL1B, EDN1, HIF1A, GAS6, ADIPOQ, NFE2L2, ESR2, AGER, CD69 |
cellular response to dsRNA | biological_process | NFKB1, TLR3 |
cellular response to electrical stimulus | biological_process | IGF1, HIF1A |
cellular response to epidermal growth factor stimulus | biological_process | AKT1, ID1, GSTP1, TDGF1, EGFR, ERRFI1, PAX2 |
cellular response to epinephrine stimulus | biological_process | STAR, ADIPOQ, SRD5A1 |
cellular response to erythropoietin | biological_process | GSK3B |
cellular response to estradiol stimulus | biological_process | IL10, ITGA2, CRHBP, SSTR1, ESR1, IGF1, EGFR, ESR2, GPER1, SRD5A1 |
cellular response to estrogen stimulus | biological_process | CRHBP, FAS, ESR1 |
cellular response to ethanol | biological_process | CCL5, DNMT3A, CCL7 |
cellular response to exogenous dsRNA | biological_process | TLR3 |
cellular response to extracellular stimulus | biological_process | ITGA6, CDKN1A, AXL, FOS, AIF1 |
cellular response to fatty acid | biological_process | SRC, CCNB1, NME1, IL1B, EDN1, AGER |
cellular response to fibroblast growth factor stimulus | biological_process | CCL5, CXCL8, CTNNB1, CD44, TDGF1, CCL2, STAR, DLL4, POSTN |
cellular response to fluid shear stress | biological_process | SRC, MMP13, PTGS2, CA2, PLAU, NFE2L2 |
cellular response to folic acid | biological_process | FOLR1 |
cellular response to follicle-stimulating hormone stimulus | biological_process | INHBA, NOTCH1, STAR |
cellular response to forskolin | biological_process | PTGER3 |
cellular response to gamma radiation | biological_process | H2AFX, EGR1, YAP1, CRYAB, BCL2L1, ATM |
cellular response to glucocorticoid stimulus | biological_process | AHR, GSTP1, FLT3, SSTR5, ANXA1, EDN1, HEY1, CRHR2, IL17A, STC1, UCN2 |
cellular response to glucose starvation | biological_process | BCL2, TP53, NFE2L2 |
cellular response to glucose stimulus | biological_process | PTGER4, SERPINF1, NME1, LGALS1, IL1R1, FAS, PIK3CA, CMA1, STAR, FN1, IL1B, PLAU, ICAM1, HIF1A, GAS6, AGER, GPER1, PAX2, IRS2, CPB2 |
cellular response to glucoside | biological_process | NFKB1 |
cellular response to glyoxal | biological_process | PARK7 |
cellular response to gonadotropin stimulus | biological_process | WT1, LHCGR, STAR, CYP17A1, GATA6 |
cellular response to gonadotropin-releasing hormone | biological_process | ANXA5, CRHBP |
cellular response to granulocyte colony-stimulating factor | biological_process | FGA |
cellular response to granulocyte macrophage colony-stimulating factor stimulus | biological_process | MAPK1, AKT1 |
cellular response to growth factor stimulus | biological_process | BMP4, CLU, AKT1, SHC1, CTNNB1, TNFRSF1B, SPARC, INSR, TGFB1, ERBB2, FYN, ANGPT2, CAT, GAS6, TWIST1, SRD5A1 |
cellular response to growth hormone stimulus | biological_process | STAR |
cellular response to heat | biological_process | CDKN1A, HSPA6, HMOX1, MKI67, FGF1, IL1A, CXCL10, PDCD6, THBS1, HDAC2, HSF1 |
cellular response to heparin | biological_process | EGR1 |
cellular response to hepatocyte growth factor stimulus | biological_process | GSK3B, IL10, HGF, TDGF1, NRP1, PLAU, IL6, RELA |
cellular response to high density lipoprotein particle stimulus | biological_process | CCL5, CCL2 |
cellular response to hormone stimulus | biological_process | STAT3, IGFBP2, LIPC, OXTR, JUN, FOS, AIF1 |
cellular response to hydrogen peroxide | biological_process | GSK3B, AKR1B1, APEX1, F3, FAS, STAT6, ANXA1, IL6, HDAC2, RELA, PARK7, HIF1A, FOXO1, NFE2L2, EZH2, SIRT1, AGER, PAX2, CYP1B1 |
cellular response to hydroperoxide | biological_process | CD36, AIF1 |
cellular response to hydrostatic pressure | biological_process | FAS |
cellular response to hyperoxia | biological_process | PPARG, FAS, FOXO1, DNMT3B |
cellular response to hypoxia | biological_process | BCL2, SRC, VEGFA, AKT1, CCNB1, HMOX1, FAS, PTN, MTOR, PTGS2, TP53, SUV39H1, TERT, PLAU, ICAM1, EDN1, PTEN, DNMT3A, HIF1A, EIF4EBP1, SIRT1, TWIST1, ADAM8, GATA6, SUV39H2, STC1, UCN2 |
cellular response to indole-3-methanol | biological_process | CDH1, CTNNB1, BRCA1, CTNNA1 |
cellular response to insulin stimulus | biological_process | SRC, PPARG, PIK3R1, AKT1, SHC1, GSTP1, USF1, CCL2, STAR, INSR, IGF1, HIF1A, FOXO1, PAK1, ADIPOQ, KAT2B, ERRFI1, IRS2, SRD5A1 |
cellular response to insulin-like growth factor stimulus | biological_process | CTNNB1 |
cellular response to interferon-alpha | biological_process | GATA3, AXL, STAR, GAS6 |
cellular response to interferon-beta | biological_process | TLR3 |
cellular response to interferon-gamma | biological_process | NOS2, WNT5A, CCL5, IL12B, CCL3, TDGF1, CCL2, MRC1, STAR, LGALS9, CCL25, CCL21, CCL22, TLR3, CCL16, EDN1, AIF1, CCL19, DAPK1, CCL7, CX3CL1, CCL17, CCL11 |
cellular response to interleukin-1 | biological_process | CCL5, CHI3L1, CXCL8, PTGER4, CCL3, NFKB1, FAS, CCL2, PTGER3, FN1, CCL25, CCL21, CCL22, CCL16, ICAM1, IL6, EDN1, RELA, HIF1A, CCL19, CCL7, CX3CL1, IL17A, CCL17, CCL11 |
cellular response to interleukin-13 | biological_process | ALOX15 |
cellular response to interleukin-18 | biological_process | IFNG |
cellular response to interleukin-3 | biological_process | GSK3B, CSF2RB |
cellular response to interleukin-4 | biological_process | GATA3, MRC1, IL24 |
cellular response to interleukin-6 | biological_process | NFKB1, TDGF1, CCL2, FGA, RELA |
cellular response to ionizing radiation | biological_process | CDKN1A, ITGB1, CLOCK, TP53, SIRT1 |
cellular response to iron ion | biological_process | BMP6, TF |
cellular response to iron(II) ion | biological_process | GSK3B |
cellular response to iron(III) ion | biological_process | CCNB1 |
cellular response to jasmonic acid stimulus | biological_process | AKR1C3, AKR1C2, AKR1C1 |
cellular response to L-ascorbic acid | biological_process | LEP |
cellular response to laminar fluid shear stress | biological_process | NFE2L2 |
cellular response to lead ion | biological_process | DNMT1, ANXA5 |
cellular response to leptin stimulus | biological_process | STAT3, LEP |
cellular response to light stimulus | biological_process | HIF1A |
cellular response to lipid | biological_process | CCL5, IL1B, HIF1A |
cellular response to lipopolysaccharide | biological_process | SRC, NOS2, WNT5A, CCL5, CD36, IL10, IL12B, CXCL8, NFKB1, CCR5, TNFRSF1B, CD40, AXL, GSTP1, CCL2, MRC1, IL12A, PTGER3, STAR, FN1, CYP17A1, IFNG, TNF, CXCL10, TLR4, SERPINE1, IL1B, PLAU, ICAM1, CSF2, IL6, RELA, HIF1A, IL24, CXCL16, KLRK1, LILRB1 |
cellular response to lipoprotein particle stimulus | biological_process | CCL2 |
cellular response to lipoteichoic acid | biological_process | CD36, TLR2, TLR4 |
cellular response to lithium ion | biological_process | GSK3B, CDH1, CTNNB1, CDKN1B, FAS, XRCC4, ID2 |
cellular response to low-density lipoprotein particle stimulus | biological_process | CD36, FCER1G, ITGB1, ITGB2 |
cellular response to luteinizing hormone stimulus | biological_process | STAR |
cellular response to macrophage colony-stimulating factor stimulus | biological_process | CCL2, CSF1R |
cellular response to magnetism | biological_process | ESR2 |
cellular response to mechanical stimulus | biological_process | GSK3B, BMP4, TNFRSF1A, GJA1, AKT1, CTNNB1, PTGER4, NFKB1, CASP1, CD40, EDNRA, ITGA2, MMP7, FAS, BMP6, IL13, PTGS2, ITGB1, TLR4, TLR3, CTSB, IL1B, IGF2, RAC1, HIF1A |
cellular response to mercury ion | biological_process | AQP2, FN1, IL4 |
cellular response to metal ion | biological_process | HSD17B1, STAR, FSTL3 |
cellular response to methotrexate | biological_process | IL1B |
cellular response to methylglyoxal | biological_process | AKR1B1 |
cellular response to mineralocorticoid stimulus | biological_process | EDN1, GPER1 |
cellular response to molecule of bacterial origin | biological_process | WNT5A |
cellular response to morphine | biological_process | CCL5, OPRM1, AIF1 |
cellular response to muramyl dipeptide | biological_process | NOD2, NOD1, PTPN22 |
cellular response to mycophenolic acid | biological_process | EGR1 |
cellular response to nerve growth factor stimulus | biological_process | DNMT1, AKT1, ID1, NTRK2 |
cellular response to nicotine | biological_process | NFKB1, TNF, RELA |
cellular response to nitric oxide | biological_process | MMP3, FOXO1 |
cellular response to nitrite | biological_process | HIF1A |
cellular response to nitrogen starvation | biological_process | GABARAPL1 |
cellular response to nitrosative stress | biological_process | ATM |
cellular response to nutrient | biological_process | HMOX1 |
cellular response to nutrient levels | biological_process | MTOR, ICAM1, UCN2 |
cellular response to organic cyclic compound | biological_process | STAT3, CCL5, AKT1, CCNB1, CCL3, NFKB1, CDKN1B, CASP3, IGFBP5, ITGA2, LGALS1, FAS, CCL2, PTN, STAR, TGFB1, FGA, TNF, IL1B, PAK4, CYP1A1, HIF1A, ESR2, IL18, AGER, CYP1B1, SRD5A1 |
cellular response to organic substance | biological_process | BCL2, EGR1, CCND1, MAPK1, SLC6A4, CASP1, CASP3, TIMP3, IL1B, PLAU, ICAM1, PSAP, SYP, BAX, TBX21 |
cellular response to organonitrogen compound | biological_process | APEX1 |
cellular response to oxidative stress | biological_process | BMP4, SOD1, GPX1, PARK7, FOXO1, NFE2L2, KAT2B |
cellular response to parathyroid hormone stimulus | biological_process | KAT2B |
cellular response to peptide | biological_process | AKR1B1, AKT1, NFKB1, ID1, IL1RL1, KLF10, IRS2 |
cellular response to peptide hormone stimulus | biological_process | SRC, APEX1, NFKB1, CYP11A1, FYN, WNT1, EDN1, RELA, GPER1 |
cellular response to phenylalanine | biological_process | FAS |
cellular response to phosphate starvation | biological_process | COMT |
cellular response to platelet-derived growth factor stimulus | biological_process | SRC, DNMT1, CCL2, PTN, FN1, FYN, ERRFI1 |
cellular response to potassium ion | biological_process | CRHBP, SOD1 |
cellular response to potassium ion starvation | biological_process | JUN |
cellular response to progesterone stimulus | biological_process | SRC |
cellular response to prostaglandin D stimulus | biological_process | TNC, AKR1C3, PTGFR, AKR1C2 |
cellular response to prostaglandin E stimulus | biological_process | PPARG, AKT1, PTGER4, PTGER2, FN1 |
cellular response to prostaglandin stimulus | biological_process | PPARG, AKR1C3 |
cellular response to reactive nitrogen species | biological_process | STAT6 |
cellular response to reactive oxygen species | biological_process | SRC, PDGFRA, AKR1C3, FOS, PARK7 |
cellular response to retinoic acid | biological_process | YAP1, WNT5A, PPARG, LEP, SERPINF1, SLC6A4, WNT2, CCL2, TNC, HDAC2, PAX2 |
cellular response to sorbitol | biological_process | MAP2K7 |
cellular response to starvation | biological_process | AKR1C3, FOXO1, GAS6, SIRT1, EHMT2, KLF10, WNT4, SRD5A1 |
cellular response to staurosporine | biological_process | PLAU |
cellular response to steroid hormone stimulus | biological_process | NR3C1 |
cellular response to stress | biological_process | OPRM1, CRHBP |
cellular response to testosterone stimulus | biological_process | SRD5A1 |
cellular response to thyroid hormone stimulus | biological_process | BMP4, KIT, CTSB, KLF9 |
cellular response to toxic substance | biological_process | HIF1A |
cellular response to transforming growth factor beta stimulus | biological_process | SRC, DNMT1, WNT5A, CCL5, WNT2, ID1, COL4A2, STAR, FN1, TGFB1, FYN, SMAD7, WNT7A, EDN1, PTK2, HDAC2, WNT4, POSTN |
cellular response to triacyl bacterial lipopeptide | biological_process | TLR2 |
cellular response to tumor necrosis factor | biological_process | GATA3, CCL5, CHI3L1, CXCL8, BRCA1, CCL3, NFKB1, CRHBP, FAS, TDGF1, CCL2, VCAM1, CCL25, CCL21, CCL22, CCL16, TNFRSF21, ICAM1, IL6, EDN1, RELA, NTRK2, NFE2L2, CCL19, SIRT1, GPER1, CCL7, CX3CL1, POSTN, CCL17, CCL11 |
cellular response to UV | biological_process | PCNA, PIK3R1, PTN, PTGS2, TP53, MYC, BAX, TP63 |
cellular response to UV-A | biological_process | MME |
cellular response to UV-B | biological_process | MME, CDKN1A |
cellular response to vascular endothelial growth factor stimulus | biological_process | VEGFA, AKT1, NOTCH1, KDR, FLT4, FLT1, VCAM1, FN1, HSPB1, NRP1, DLL4 |
cellular response to virus | biological_process | IL12A, LGALS9, CCL19 |
cellular response to vitamin D | biological_process | IL15, PTN, TNC, ITGB1 |
cellular response to vitamin E | biological_process | PPARG |
cellular response to vitamin K | biological_process | CCL5, GAS6, POSTN |
cellular response to water deprivation | biological_process | AQP2 |
cellular response to xenobiotic stimulus | biological_process | RB1 |
cellular senescence | biological_process | H2AFX, CDKN1A, CDKN2A, ID2 |
cellular sodium ion homeostasis | biological_process | AGTR2, SGK1 |
cellular triglyceride homeostasis | biological_process | SIRT1 |
cellular water homeostasis | biological_process | AQP2, AQP8, AQP5 |
central nervous system development | biological_process | SRC, GSTP1, VCAN, TIMP2, TIMP3, ZEB1, ALDH3A2, FYN, PTEN, ADAM22, TIMP4 |
central nervous system morphogenesis | biological_process | WNT1 |
central nervous system myelin maintenance | biological_process | CLU, PTEN |
central nervous system myelination | biological_process | HES5 |
central nervous system neuron axonogenesis | biological_process | PTEN, PTK2 |
central nervous system neuron development | biological_process | FGFR1, LEP, GATA2, MAP2, NTRK2, ATP7A, NPY |
central nervous system vasculogenesis | biological_process | CTNNB1, ENG, WNT7A |
centrosome cycle | biological_process | BRCA1 |
centrosome duplication | biological_process | BRCA2 |
centrosome localization | biological_process | AURKA |
centrosome organization | biological_process | AURKA, PLK1 |
cerebellar cortex development | biological_process | AGTR2, EZH2 |
cerebellar granular layer development | biological_process | MDK |
cerebellar granule cell differentiation | biological_process | WNT7A |
cerebellar Purkinje cell differentiation | biological_process | ATP7A |
cerebellar Purkinje cell layer development | biological_process | NAGLU |
cerebellum development | biological_process | PTN, SSTR1, WNT1, ESR2, CRHR2 |
cerebellum formation | biological_process | WNT1 |
cerebral cortex cell migration | biological_process | EGFR |
cerebral cortex development | biological_process | H2AFX, MDK, NTRK2, HIF1A, BAX, PLCB1, EMX2, NPY, SRD5A1 |
cerebral cortex GABAergic interneuron development | biological_process | RAC1 |
cerebral cortex GABAergic interneuron migration | biological_process | DRD2 |
cerebral cortex neuron differentiation | biological_process | CHD5 |
cerebral cortex radially oriented cell migration | biological_process | RAC1 |
cerebral cortex regionalization | biological_process | EMX2 |
cervix development | biological_process | WNT5A |
cGMP-mediated signaling | biological_process | CD36, APOE |
chaperone mediated protein folding requiring cofactor | biological_process | CD74 |
chaperone-mediated autophagy | biological_process | HSP90AA1 |
chaperone-mediated protein complex assembly | biological_process | HSPD1, CLU, HSPA4, HSP90AA1, APCS |
chaperone-mediated protein folding | biological_process | CLU, FKBP4, FKBP5 |
chemical synaptic transmission | biological_process | MAPK1, OPRM1, CTNNB1, SLC6A4, TACR2, TACR1, SLC6A2, SSTR1, SSTR5, NPTX2, SNCG, CRH, P2RX3, SST, PLCB3, LPAR3, NPY |
chemical synaptic transmission, postsynaptic | biological_process | GSK3B, AKT1, DRD2 |
chemoattraction of serotonergic neuron axon | biological_process | WNT5A |
chemokine (C-C motif) ligand 11 production | biological_process | CXCR3 |
chemokine (C-C motif) ligand 19 signaling pathway | biological_process | CCR7 |
chemokine (C-C motif) ligand 2 secretion | biological_process | FOXP1, F2RL1 |
chemokine (C-C motif) ligand 21 signaling pathway | biological_process | CCR7 |
chemokine biosynthetic process | biological_process | IL18 |
chemokine secretion | biological_process | F2RL1 |
chemokine-mediated signaling pathway | biological_process | CCL5, CXCL8, CCL3, CCR1, CCR5, CXCR3, CXCL1, CXCR1, CXCR2, CCL2, CXCL2, CCR2, CXCL5, CXCL12, CCR9, CXCL10, CCL25, CXCR6, CCL21, CCL22, CCL16, CXCL13, CXCR4, CCL19, CCL7, CX3CL1, CXCL6, CCL17, CCR7, CCL11, CCR8 |
chemokinesis | biological_process | PTGER4 |
chemorepulsion involved in interneuron migration from the subpallium to the cortex | biological_process | NRG1 |
chemorepulsion of dopaminergic neuron axon | biological_process | WNT5A |
chemosensory behavior | biological_process | TRPV1 |
chemotaxis | biological_process | FGF2, CCL5, MAPK1, HMGB1, CXCL8, CCL3, FPR1, CCR1, CCR5, CXCR3, PDGFRA, FLT1, CXCL1, CXCR1, CXCR2, CCL2, CXCL2, TYMP, L1CAM, CCR2, CXCL5, CXCL12, CCR9, CXCL10, LGALS9, CCL25, CXCR6, CCL21, CYR61, CCL22, DEFB4A, CCL16, CXCL13, CXCL14, PLAU, C5, IL4, RAC1, PLAUR, CXCR4, CCL19, RARRES2, CCL7, CX3CL1, DEFB1, CXCL6, IL16, CCL17, CXCL16, CCL27, CCR7, CCL11, CCR8 |
chitin catabolic process | biological_process | CHI3L1, OVGP1 |
chloride transmembrane transport | biological_process | CFTR, CLCN3, SLC26A8 |
chloride transport | biological_process | CFTR, CLCN3, SLC26A8 |
cholangiocyte proliferation | biological_process | MKI67 |
cholesterol biosynthetic process | biological_process | CFTR, APOA1, ACLY, HSD17B7 |
cholesterol catabolic process | biological_process | AKR1D1, APOE, SCARB1 |
cholesterol efflux | biological_process | APOA1, APOA2, APOE, SCARB1 |
cholesterol homeostasis | biological_process | CETP, LIPC, APOA1, APOA2, APOE, NR5A2, SIRT1, SCARB1, AKR1C1 |
cholesterol import | biological_process | CD36, APOA1, SCARB1 |
cholesterol metabolic process | biological_process | CETP, LEP, LIPC, LEPR, PON1, STAR, CYP11A1, APOA1, APOA2, APOE, CAT, IL4, NR0B2 |
cholesterol transport | biological_process | CETP, CFTR, CD36, LIPC, APOA1, APOA2, SCARB1 |
choline metabolic process | biological_process | BCHE |
chondroblast differentiation | biological_process | FGF2, CYR61 |
chondrocyte development | biological_process | BMPR1B |
chondrocyte differentiation | biological_process | FGFR1, BMP4, HMGA2, TGFB1, BMPR1B, WNT7A, RUNX3, HES5 |
chondrocyte proliferation | biological_process | HMGA2, MMP14, STC1 |
chondroitin sulfate biosynthetic process | biological_process | BGN, VCAN, XYLT2, DCN |
chondroitin sulfate catabolic process | biological_process | BGN, VCAN, DCN |
chondroitin sulfate proteoglycan biosynthetic process | biological_process | XYLT2 |
chordate embryonic development | biological_process | FGFR1, BRCA1, BRCA2, FAS |
chorio-allantoic fusion | biological_process | CYR61 |
chorionic trophoblast cell differentiation | biological_process | HTRA1 |
chromatin assembly | biological_process | HMGB1, TP53 |
chromatin assembly or disassembly | biological_process | SUV39H2 |
chromatin organization | biological_process | HMGA2, SOX2, SUV39H1, ARID1A, SOX15, EZH2, SIRT1 |
chromatin remodeling | biological_process | GATA3, ESR1, MYC, RB1, ARID1A, HDAC2, KAT2B, HDAC1, FOXP3, TP63, SUV39H2 |
chromatin silencing | biological_process | H2AFX, SIRT1 |
chromatin silencing at rDNA | biological_process | SUV39H1, SIRT1, HIST2H3A, MBD2 |
chromatin-mediated maintenance of transcription | biological_process | CTNNB1, ARID1A |
chromosome breakage | biological_process | HMGA2, BRCA1, BRCA2 |
chromosome condensation | biological_process | HMGA2, PRM1 |
chromosome organization | biological_process | BRCA2, MYC |
chromosome segregation | biological_process | BRCA1, BIRC5, NR3C1, CEP85 |
chronic inflammatory response | biological_process | CCL5, GJA1, VCAM1, PTGES, THBS1, CXCL13, CCL11 |
chronic inflammatory response to antigenic stimulus | biological_process | TNF, IL1B |
chronological cell aging | biological_process | ENG, SERPINE1 |
chylomicron remnant clearance | biological_process | LIPC, APOE |
chylomicron remodeling | biological_process | LIPC |
ciliary body morphogenesis | biological_process | JAG1 |
ciliary neurotrophic factor-mediated signaling pathway | biological_process | IL6R, IL6ST, CNTF, LIFR |
cilium assembly | biological_process | NOTCH1 |
circadian behavior | biological_process | TP53 |
circadian regulation of gene expression | biological_process | AHR, DRD2, HNF1B, CLOCK, HDAC2, PPARA, HDAC1, SIRT1, ID2 |
circadian rhythm | biological_process | GSK3B, NOS2, LEP, SLC6A4, ID1, LIPC, FAS, STAR, JUN, CLOCK, CLDN4, SERPINE1, NTRK2, ADIPOQ, SIRT1, ID2, KLF10, PROK1, KLF9 |
circadian sleep/wake cycle, REM sleep | biological_process | STAR, SRD5A1 |
citrate metabolic process | biological_process | ACLY |
Clara cell differentiation | biological_process | GATA6 |
cleavage furrow formation | biological_process | RHOA |
cloacal septation | biological_process | BMP4, TP63 |
cocaine metabolic process | biological_process | BCHE |
cochlea development | biological_process | PAX2 |
cochlea morphogenesis | biological_process | WNT5A, ZEB1, RAC1, PAX2 |
cochlear nucleus development | biological_process | BCL2 |
cognition | biological_process | LHCGR, HLA-DRA |
collagen catabolic process | biological_process | MMP13, MMP9, COL4A2, MMP7, MMP10, MMP14, MMP11, COL18A1, MMP12, CTSB, COL4A1, MMP1, CTSD, COL5A2, MMP2, MMP3 |
collagen fibril organization | biological_process | MMP11, GREM1, ANXA2, COL5A2, TGFB2, ATP7A, CYP1B1 |
collagen metabolic process | biological_process | ID1, HIF1A |
collagen-activated signaling pathway | biological_process | ITGA2 |
collateral sprouting | biological_process | BDNF |
collecting duct development | biological_process | NOTCH1 |
comma-shaped body morphogenesis | biological_process | HES5 |
commissural neuron axon guidance | biological_process | VEGFA, NRP1 |
commitment of neuronal cell to specific neuron type in forebrain | biological_process | GATA2 |
common myeloid progenitor cell proliferation | biological_process | GSTP1, FLT3 |
common-partner SMAD protein phosphorylation | biological_process | BMP4, TGFB1, SMAD2 |
compartment pattern specification | biological_process | NOTCH1 |
complement activation | biological_process | CLU, MBL2, C4A, C3, C5 |
complement activation, alternative pathway | biological_process | C3, C5 |
complement activation, classical pathway | biological_process | CLU, MBL2, C4A, C3, C5, C4BPA, C1QBP |
complement activation, lectin pathway | biological_process | MBL2, KRT1 |
conditioned taste aversion | biological_process | FOS |
connective tissue growth factor biosynthetic process | biological_process | IL4 |
connective tissue replacement involved in inflammatory response wound healing | biological_process | F2R, TGFB1, IL1A, HIF1A |
contact inhibition | biological_process | YAP1 |
convergent extension | biological_process | WNT5A |
convergent extension involved in axis elongation | biological_process | WNT5A |
convergent extension involved in organogenesis | biological_process | WNT5A |
conversion of ds siRNA to ss siRNA | biological_process | DICER1 |
conversion of ds siRNA to ss siRNA involved in RNA interference | biological_process | DICER1 |
COPII vesicle coating | biological_process | FOLR1, SERPINA1, STX5 |
copper ion export | biological_process | ATP7A |
copper ion import | biological_process | ATP7A |
copper ion transport | biological_process | CP, FKBP4, ATP7A |
coronary artery morphogenesis | biological_process | VEGFA, NOTCH1, NRP1 |
coronary vasculature development | biological_process | PRDM1, PCSK5 |
coronary vein morphogenesis | biological_process | VEGFA, NOTCH1 |
cortical actin cytoskeleton organization | biological_process | TNF |
corticotropin secretion | biological_process | CRHR1 |
cortisol metabolic process | biological_process | CYP11A1 |
cortisol secretion | biological_process | GHRL |
coumarin catabolic process | biological_process | CYP2A6 |
coumarin metabolic process | biological_process | CYP2A6, CYP1A1 |
cranial ganglion development | biological_process | CTNNB1 |
cranial nerve development | biological_process | ERBB3 |
cranial suture morphogenesis | biological_process | BMP4, TWIST1 |
craniofacial suture morphogenesis | biological_process | MMP14 |
CRD-mediated mRNA stabilization | biological_process | YBX1 |
creatinine metabolic process | biological_process | MME |
CTP biosynthetic process | biological_process | NME1 |
cullin deneddylation | biological_process | COPS5 |
cyclooxygenase pathway | biological_process | PTGDS, PTGS1, PTGS2, AKR1C3, PTGES |
cysteine metabolic process | biological_process | GCLC |
cytokine biosynthetic process | biological_process | PCSK5, IL17F |
cytokine production | biological_process | CD4, FOXP3, MAF |
cytokine production involved in immune response | biological_process | NOD2 |
cytokine production involved in inflammatory response | biological_process | IDO1 |
cytokine secretion | biological_process | S100A13 |
cytokine secretion involved in immune response | biological_process | TLR2, NOD2 |
cytokine-mediated signaling pathway | biological_process | STAT3, TNFRSF1A, BGN, F3, KIT, IL12B, CCR1, CSF2RB, IL6R, IL6ST, IL1R1, CCL2, IL2RB, LIFR, STAT6, IL1R2, FLT3, CCR2, IL1A, SOCS3, IL1B, KRAS, IL5, IL6, CSF1R, RELA, CX3CL1, IL10RB, IL22RA1, IL11RA, IL20RB, IL1RAP, IL37, IL20RA, DCN |
cytokinesis | biological_process | BRCA2, RHOC, BIRC5, PLK1, BCL2L1 |
cytolysis | biological_process | C5, MICA, MICB |
cytoplasmic sequestering of NF-kappaB | biological_process | IL10, CCDC22, PSMD10 |
cytoplasmic sequestering of protein | biological_process | LATS1 |
cytosine metabolic process | biological_process | MAPK1, TET2 |
cytoskeleton organization | biological_process | CFL1, CCL3, CCL2, APOE, LAMA5, PAK4, RAC1, DPYSL2, CCL7, KISS1, CCL11 |
dATP catabolic process | biological_process | ADA |
daunorubicin metabolic process | biological_process | AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
death-inducing signaling complex assembly | biological_process | TNFRSF1A, TNF |
decidualization | biological_process | PLA2G4A, SPP1, VDR, LIF, PTGS2, BSG, ESR1, CTSB, GHRL, STC1 |
defecation | biological_process | MDK |
defense response | biological_process | GATA3, INHBA, TNFRSF1A, TNF, DEFB4A, TLR3, HP, CD74, MPO, RELA, HSF1, NOD2, MST1R, NOD1, TPSAB1, CX3CL1, DEFB1, CD83, TFF3 |
defense response to bacterium | biological_process | NOS2, TNFRSF1A, IL10, MBL2, LPO, FCER1G, CCR2, IFNG, LTF, TNF, TLR4, SLPI, DEFB4A, TLR3, CXCL13, HP, CTSG, TLR9, NOD2, NOD1, MICA, DEFB1, CXCL6, HAMP |
defense response to fungus | biological_process | MPO, CTSG, HAMP, IL17A |
defense response to fungus, incompatible interaction | biological_process | TGFB1 |
defense response to Gram-negative bacterium | biological_process | NOS2, IL12B, IL6R, SELP, ADM, TLR4, CD4, SERPINE1, IL6, TLR9, IL23A, IL22RA1, NPY |
defense response to Gram-positive bacterium | biological_process | CD36, MBL2, IL6R, HLA-E, PLA2G2A, IL12A, ADM, ANG, TNF, TLR2, CRP, LTA, IL6, CTSG, NOD1, ADAM17, DEFB1, NPY, KLRK1 |
defense response to protozoan | biological_process | IL10, IL12B, CD40, IL12A, IFNG, IL4, IL6 |
defense response to virus | biological_process | BCL2, IL12B, CD40, IFNG, CXCL10, TLR3, IL33, IL6, RELA, F2RL1, MICA, IL23A, IL10RB, ISG20, LILRB1 |
definitive hemopoiesis | biological_process | GATA2, MEIS1, TEK |
deltoid tuberosity development | biological_process | BMP4 |
demethylation | biological_process | CYP1A1 |
dendrite development | biological_process | NRP1, RAC1, HDAC2, GHRL |
dendrite morphogenesis | biological_process | MAP2, ITGB1, FYN, RAC1, SEMA3A |
dendrite regeneration | biological_process | FAS |
dendritic cell chemotaxis | biological_process | CCL5, HMGB1, CCR1, CCR5, CXCR1, CXCR2, CCR2, CCL21, CXCR4, CCL19, CCR7 |
dendritic cell cytokine production | biological_process | KIT |
dendritic cell dendrite assembly | biological_process | CCL21 |
dendritic cell differentiation | biological_process | AXL, FLT3, CSF2, IL4, GAS6, LILRB1 |
dendritic cell migration | biological_process | CDC42 |
dendritic spine development | biological_process | PAK4 |
dendritic spine maintenance | biological_process | ITGA3 |
dendritic spine morphogenesis | biological_process | WNT7A, PTEN |
dentate gyrus development | biological_process | MDK, PTEN, EMX2 |
dentinogenesis | biological_process | HTRA1 |
deoxyadenosine catabolic process | biological_process | ADA |
dephosphorylation | biological_process | PON1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR, SGPP2 |
depurination | biological_process | OGG1 |
depyrimidination | biological_process | OGG1 |
dermatan sulfate biosynthetic process | biological_process | BGN, VCAN, DCN |
desensitization of G-protein coupled receptor protein signaling pathway | biological_process | PTGER3 |
desmosome organization | biological_process | NECTIN1 |
detection of abiotic stimulus | biological_process | TACR1 |
detection of bacterium | biological_process | HLA-DRB1, HLA-A, NOD2, NOD1 |
detection of biotic stimulus | biological_process | NOD2, NOD1 |
detection of chemical stimulus involved in sensory perception of bitter taste | biological_process | AZGP1, LPO |
detection of diacyl bacterial lipopeptide | biological_process | TLR2 |
detection of fungus | biological_process | TLR4 |
detection of hypoxia | biological_process | ENG |
detection of lipopolysaccharide | biological_process | TLR4, SCARB1 |
detection of mechanical stimulus involved in sensory perception | biological_process | IGF1 |
detection of mechanical stimulus involved in sensory perception of pain | biological_process | ITGA2, FYN |
detection of mechanical stimulus involved in sensory perception of sound | biological_process | KIT |
detection of muramyl dipeptide | biological_process | NOD2 |
detection of oxidative stress | biological_process | ADIPOQ |
detection of stimulus | biological_process | CADM1 |
detection of temperature stimulus involved in sensory perception of pain | biological_process | MMP24 |
detection of triacyl bacterial lipopeptide | biological_process | TLR2 |
detection of virus | biological_process | TLR3 |
determination of adult lifespan | biological_process | MSH2, MSH6, TP53, ATM |
determination of dorsal identity | biological_process | GREM1 |
determination of left/right symmetry | biological_process | WNT5A, NOTCH1, PCSK5, NODAL |
detoxification of copper ion | biological_process | PARK7, ATP7A |
detoxification of mercury ion | biological_process | PARK7 |
development of primary male sexual characteristics | biological_process | WNT5A |
development of secondary sexual characteristics | biological_process | BAX |
developmental growth | biological_process | BCL2, GATA3, LIPC, HOXA11, ADM, PSAP, SMAD3, SMAD2, SMAD4 |
developmental pigmentation | biological_process | BCL2, KIT, BCL2L11 |
developmental process | biological_process | COMT, CYP1A1, TP63, IL11RA |
developmental process involved in reproduction | biological_process | CSF1 |
diacylglycerol biosynthetic process | biological_process | ANG |
diacylglycerol catabolic process | biological_process | APOA2 |
diapedesis | biological_process | PECAM1 |
diaphragm development | biological_process | WT1 |
dibenzo-p-dioxin catabolic process | biological_process | CYP1A1 |
dibenzo-p-dioxin metabolic process | biological_process | CCL5, SRD5A2, STAR, CYP17A1, CYP1A2, CYP1A1 |
dichotomous subdivision of terminal units involved in salivary gland branching | biological_process | NRP1, SEMA3A, SEMA3C |
diencephalon development | biological_process | WNT1 |
digestion | biological_process | AKR1D1, SSTR1, AKR1C2, AKR1C1, SST, NPY, TFF3, UCN2 |
digestive system development | biological_process | NODAL |
digestive tract development | biological_process | GATA3, ITGA6, FGFR2, KIT, CCNB1, GATA2, OXTR, TGFB1, RB1, CYP1A1 |
digestive tract morphogenesis | biological_process | BCL2, WNT5A, EGFR, AGR2, HIF1A, NODAL |
distal tubule development | biological_process | NOTCH1, JAG1 |
diterpenoid metabolic process | biological_process | STAR, CRH, SRD5A1 |
DNA biosynthetic process | biological_process | TERT |
DNA catabolic process, exonucleolytic | biological_process | ISG20 |
DNA damage checkpoint | biological_process | H2AFX, CHEK2, CLOCK, ATM |
DNA damage induced protein phosphorylation | biological_process | CHEK2, ATM |
DNA damage response, detection of DNA damage | biological_process | PCNA, HMGA2 |
DNA damage response, signal transduction by p53 class mediator | biological_process | MIF, TP53 |
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | biological_process | PCNA, CCNB1, CDKN1B, CDKN1A, MUC1, CHEK2, AURKA, TP53, BAX, ATM |
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological_process | BRCA1, MUC1, BRCA2, TP53, TP63 |
DNA demethylation | biological_process | APEX1, TET3, TET2, TET1 |
DNA demethylation of male pronucleus | biological_process | TET3 |
DNA double-strand break processing | biological_process | BRCA1, ATM |
DNA duplex unwinding | biological_process | ANXA1 |
DNA geometric change | biological_process | HMGB1 |
DNA hypermethylation | biological_process | DNMT1 |
DNA ligation involved in DNA repair | biological_process | HMGB1, XRCC4 |
DNA metabolic process | biological_process | NME1, IGFBP4, MKI67 |
DNA methylation | biological_process | DNMT1, FOS, DNMT3A, EZH2, EHMT2, DNMT3B, DNMT3L |
DNA methylation involved in embryo development | biological_process | DNMT3A |
DNA methylation involved in gamete generation | biological_process | DNMT3A |
DNA methylation on cytosine | biological_process | DNMT1, DNMT3A |
DNA methylation on cytosine within a CG sequence | biological_process | DNMT1, DNMT3A, DNMT3B |
DNA packaging | biological_process | PRM1 |
DNA recombination | biological_process | H2AFX, HMGB1, APEX1, BRCA1, BRCA2, XRCC3, XRCC4 |
DNA repair | biological_process | MSH2, MSH6, H2AFX, MLH1, PCNA, HMGB1, APEX1, BRCA1, XRCC1, BRCA2, MTOR, CHEK2, XRCC3, XRCC4, SIRT1, ATM, PMS2, OGG1 |
DNA replication | biological_process | PCNA, BRCA1, TYMP, IGF1, EGF, SET, SIRT1, ATM |
DNA rewinding | biological_process | ANXA1 |
DNA strand elongation | biological_process | TERT |
DNA strand elongation involved in DNA replication | biological_process | PCNA |
DNA strand renaturation | biological_process | ANXA1, TP53 |
DNA synthesis involved in DNA repair | biological_process | BRCA1, BRCA2, XRCC3, SIRT1, ATM |
DNA topological change | biological_process | HMGB1 |
DNA unwinding involved in DNA replication | biological_process | HMGA1 |
DNA-templated transcription, initiation | biological_process | TBPL2 |
dopamine biosynthetic process | biological_process | AGTR2, TGFB2 |
dopamine catabolic process | biological_process | MAOA, COMT |
dopamine metabolic process | biological_process | DRD2, COMT, ATP7A |
dopamine receptor signaling pathway | biological_process | GSK3B, DRD2 |
dopamine uptake involved in synaptic transmission | biological_process | SLC6A2, PARK7 |
dopaminergic neuron differentiation | biological_process | VEGFA, WNT5A, CTNNB1, FIGF, WNT1, RAC1, HIF1A |
dorsal aorta morphogenesis | biological_process | HEY1, DLL4 |
dorsal root ganglion development | biological_process | CTNNB1 |
dorsal root ganglion morphogenesis | biological_process | NRP1 |
dorsal/ventral axis specification | biological_process | CTNNB1 |
dorsal/ventral neural tube patterning | biological_process | BMP4 |
dorsal/ventral pattern formation | biological_process | CTNNB1, HOXB2, HOXA11, BMPR1B, WNT7A, EDN1 |
dosage compensation by inactivation of X chromosome | biological_process | BRCA1 |
double-strand break repair | biological_process | MSH2, H2AFX, BRCA1, BRCA2, CHEK2, XRCC4 |
double-strand break repair via homologous recombination | biological_process | H2AFX, BRCA1, XRCC1, BRCA2, XRCC3, ATM |
double-strand break repair via nonhomologous end joining | biological_process | H2AFX, MLH1, BRCA1, XRCC4, ATM, HIST3H3 |
doxorubicin metabolic process | biological_process | AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
drinking behavior | biological_process | UCN |
drug catabolic process | biological_process | CYP1A2 |
drug export | biological_process | ABCG2 |
drug metabolic process | biological_process | CYP2A6, CYP2B6, CYP2C19, CYP2E1, CYP1A2, CYP1A1 |
drug transmembrane transport | biological_process | ABCB1, ABCG2 |
drug transport | biological_process | ABCG2 |
ductus arteriosus closure | biological_process | HPGD, PTGER4 |
ear development | biological_process | BCL2, GATA3, BCL2L11, DLX5 |
early endosome to Golgi transport | biological_process | STX5 |
eating behavior | biological_process | STAT3, LEP, OPRM1, UCHL1, TACR1, OXTR |
ectoderm and mesoderm interaction | biological_process | TP63 |
ectoderm development | biological_process | CTNNB1 |
ectodermal cell differentiation | biological_process | ITGA6 |
ectopic germ cell programmed cell death | biological_process | KIT, KITLG, IL1A, IL1B, BAX |
elastic fiber assembly | biological_process | ATP7A |
elastin biosynthetic process | biological_process | ATP7A |
elastin metabolic process | biological_process | HIF1A |
electron transport chain | biological_process | MT-CO2 |
embryo development | biological_process | ATP5A1, TDGF1, NR5A2, LAMA5, TGFB2, PTK2, NRG1, NOTCH4 |
embryo development ending in birth or egg hatching | biological_process | CYP1A1 |
embryo implantation | biological_process | FBLN1, MMP9, SPP1, PRLR, LIF, PTGS2, BSG, SOD1, IL1B, PLAU, MMP2, FKBP4, PCSK5, TRO, IL11RA, STC1 |
embryonic axis specification | biological_process | CTNNB1, WNT7A, WNT1 |
embryonic brain development | biological_process | CTNNB1, WNT1 |
embryonic camera-type eye formation | biological_process | TWIST1 |
embryonic camera-type eye morphogenesis | biological_process | ZEB1 |
embryonic cranial skeleton morphogenesis | biological_process | BMP4, FGFR2, CTNNB1, PDGFRA, MMP14, SMAD3, SMAD2, TWIST1, NODAL |
embryonic digestive tract development | biological_process | CXCL8, TNF, ADA, TGFB2, RARRES2, PCSK5 |
embryonic digestive tract morphogenesis | biological_process | FGFR2, PDGFRA, HNF1B, ID2 |
embryonic digit morphogenesis | biological_process | BMP4, WNT5A, GJA1, CTNNB1, HOXA11, WNT7A, HDAC2, HDAC1, SMAD4, TWIST1, IHH |
embryonic epithelial tube formation | biological_process | WNT4 |
embryonic eye morphogenesis | biological_process | FOXL2 |
embryonic foregut morphogenesis | biological_process | CTNNB1, SMAD3, SMAD2 |
embryonic forelimb morphogenesis | biological_process | CTNNB1, HOXA11, WNT7A, TWIST1 |
embryonic heart tube development | biological_process | GJA1, CTNNB1, NODAL |
embryonic heart tube morphogenesis | biological_process | YAP1 |
embryonic hemopoiesis | biological_process | GATA3, KIT, KDR, KITLG, HIF1A |
embryonic hindlimb morphogenesis | biological_process | BMP4, MMP13, CTNNB1, NOTCH1, WNT7A, TWIST1 |
embryonic limb morphogenesis | biological_process | FGFR1, BMP4, WNT5A, NOTCH1, HOXA10, HOXA11, GREM1, WNT7A, DKK1, TWIST1, TP63, DLX5 |
embryonic lung development | biological_process | PDGFA |
embryonic morphogenesis | biological_process | FGF2, BMP4, FLT1, HNF1B, ZEB1 |
embryonic olfactory bulb interneuron precursor migration | biological_process | RAC1 |
embryonic organ development | biological_process | GATA3, FGFR2 |
embryonic organ morphogenesis | biological_process | FGFR2 |
embryonic pattern specification | biological_process | FGFR2, SMAD3, SMAD2, NODAL |
embryonic placenta development | biological_process | GATA2, ARNT, EGFR, PRDM1, CSF2, HIF1A, HSF1, NODAL |
embryonic process involved in female pregnancy | biological_process | HSF1, ABCG2, NODAL |
embryonic skeletal joint morphogenesis | biological_process | BMP4, HOXA11 |
embryonic skeletal limb joint morphogenesis | biological_process | CTNNB1 |
embryonic skeletal system development | biological_process | BMP4, WNT5A, PCSK5 |
embryonic skeletal system morphogenesis | biological_process | BMP4, PDGFRA, HOXB2, ZEB1, TWIST1 |
enamel mineralization | biological_process | FOXO1, PPARA, NECTIN1 |
endocardial cell differentiation | biological_process | NOTCH1, NRG1, SMAD4 |
endocardial cushion cell development | biological_process | JAG1 |
endocardial cushion development | biological_process | BMP4, ERBB3, NOTCH1 |
endocardial cushion morphogenesis | biological_process | NOTCH1, TGFB2, HEY1, TWIST1 |
endocardial cushion to mesenchymal transition involved in heart valve formation | biological_process | EFNA1 |
endocardium development | biological_process | NOTCH1 |
endocardium morphogenesis | biological_process | NOTCH1 |
endochondral bone morphogenesis | biological_process | BMPR1B |
endochondral ossification | biological_process | BMP4, MMP13, MMP14, BMP6, TEK, DLX5 |
endocrine pancreas development | biological_process | CLU, AKT1, IL6R, HNF1B, ANXA1, IL6, FOXO1 |
endocrine signaling | biological_process | KRAS |
endocytosis | biological_process | NME1, MRC1, SYP, CDC42, RAC1, BCL2L1, DPYSL2 |
endoderm development | biological_process | NOTCH1, HNF1B, TGFB1, DKK1, SMAD3, SMAD2, SMAD4, NODAL, LAMC1 |
endoderm formation | biological_process | CTNNB1, DKK1, SMAD2, DUSP2 |
endodermal cell differentiation | biological_process | INHBA, HMGA2, MMP9, COL4A2, ITGB5, MMP14, FN1, ITGAV, ITGB2, MMP2, GATA6, NODAL |
endodermal cell fate commitment | biological_process | CTNNB1 |
endodermal cell fate determination | biological_process | GATA6 |
endodermal cell fate specification | biological_process | HNF1B, SOX2, POU5F1, NANOG |
endodermal digestive tract morphogenesis | biological_process | ID2 |
endoplasmic reticulum calcium ion homeostasis | biological_process | BCL2, BAX |
endoplasmic reticulum unfolded protein response | biological_process | CCND1, IFNG, NFE2L2, CREB3L1 |
endosomal lumen acidification | biological_process | CLCN3, FASLG |
endothelial cell activation | biological_process | CXCL10, FOXP1, SMAD4 |
endothelial cell chemotaxis | biological_process | VEGFA, HMGB1, NRP1 |
endothelial cell chemotaxis to fibroblast growth factor | biological_process | CXCL13 |
endothelial cell development | biological_process | GPX1 |
endothelial cell differentiation | biological_process | PTN, LAMA5, JAG1, NOTCH4 |
endothelial cell migration | biological_process | S100P, PIK3CA, NOS3, GREM1, PTP4A3, ITGB2, PTEN, PTK2, CYP1B1, RHOA |
endothelial cell morphogenesis | biological_process | MET, ID1, COL18A1, NOTCH4, STC1 |
endothelial cell proliferation | biological_process | HMGB1, HMOX1, MMP14, APOA1, TEK, SCARB1 |
endothelial cell-cell adhesion | biological_process | CYP1B1 |
endothelial tip cell fate specification | biological_process | NRP1 |
endothelial tube lumen extension | biological_process | RHOA |
endothelial tube morphogenesis | biological_process | CTNNB1 |
endothelin receptor signaling pathway | biological_process | EDNRA |
endothelium development | biological_process | GJA1, KDR |
energy homeostasis | biological_process | STAT3, LEPR, PIK3CA |
energy reserve metabolic process | biological_process | LEP, LEPR, MTOR, MYC |
engulfment of apoptotic cell | biological_process | THBS1, RAC1 |
enteric nervous system development | biological_process | EDNRA |
entrainment of circadian clock | biological_process | CLOCK, ID2 |
entrainment of circadian clock by photoperiod | biological_process | TP53, ID2 |
entry into host cell | biological_process | CCR5, CD4, CXCR4 |
entry of symbiont into host cell by promotion of host phagocytosis | biological_process | ITGAV |
enucleate erythrocyte differentiation | biological_process | RB1, ID2 |
enzyme active site formation via L-cysteine sulfinic acid | biological_process | PARK7 |
enzyme linked receptor protein signaling pathway | biological_process | AXL, ERBB2, CD4, GAS6 |
eosinophil chemotaxis | biological_process | CCL5, LGALS3, CCL3, CCL7, CCL11 |
eosinophil degranulation | biological_process | CCL3 |
eosinophil fate commitment | biological_process | GATA2 |
ephrin receptor signaling pathway | biological_process | CRK, SRC, MMP9, EFNA1, FYN, KALRN, MMP2, CDC42, RAC1, PTK2, ACTB, PAK1, RHOA |
epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification | biological_process | NODAL |
epidermal cell differentiation | biological_process | HDAC2, HDAC1 |
epidermal cell division | biological_process | TP63 |
epidermal growth factor receptor signaling pathway | biological_process | SRC, PIK3R1, SHC1, TDGF1, PIK3CA, EGFR, TGFB1, EGF, NRAS, KRAS, PTK2, ADAM17 |
epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade | biological_process | RASSF2 |
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway | biological_process | ADAM17 |
epidermis development | biological_process | NOTCH1, STS, NTF4, ALDH3A2, INSR, EGFR, PPARA, TP63, LAMC2 |
epidermis morphogenesis | biological_process | FGFR2, CDC42 |
epinephrine metabolic process | biological_process | ATP7A |
epithelial cell development | biological_process | ESR1, CXCR4, TP63 |
epithelial cell differentiation | biological_process | VEGFA, PCNA, PPARG, FGFR2, LGALS3, ANXA4, WT1, AKR1C2, NR5A2, TGFB1I1, CTSB, COL4A1, TP63, GATA6, TAGLN, AKR1C1, DLX5, CRHR2 |
epithelial cell differentiation involved in mammary gland alveolus development | biological_process | HIF1A, ID2 |
epithelial cell differentiation involved in prostate gland development | biological_process | CTNNB1, PSAP |
epithelial cell maturation | biological_process | GJA1 |
epithelial cell morphogenesis | biological_process | CLDN3, RAC1 |
epithelial cell proliferation | biological_process | KIT, HNF1B |
epithelial cell proliferation involved in lung morphogenesis | biological_process | BMP4 |
epithelial cell proliferation involved in mammary gland duct elongation | biological_process | WNT5A, ESR1 |
epithelial cell proliferation involved in renal tubule morphogenesis | biological_process | LGR5 |
epithelial cell proliferation involved in salivary gland morphogenesis | biological_process | FGFR2, TNF, IL6 |
epithelial cell-cell adhesion | biological_process | CTNNA1, ITGB5, CDC42 |
epithelial fluid transport | biological_process | CSF2, EDN1 |
epithelial to mesenchymal transition | biological_process | GSK3B, WNT5A, HMGA2, FGFR2, CTNNB1, NOTCH1, HGF, TGFB1, SNAI1, TGFB2, HIF1A, WNT4 |
epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | NOTCH1, SNAI1, HEY1, SMAD4 |
epithelial tube branching involved in lung morphogenesis | biological_process | BMP4, CTNNB1, KRAS |
epithelial-mesenchymal cell signaling | biological_process | BMP4, CDC42 |
epithelium development | biological_process | BMP4, HNF1B |
epoxygenase P450 pathway | biological_process | CYP2A6, CYP2B6, CYP2C19, CYP2E1, CYP1A2, CYP1A1, CYP1B1 |
ER overload response | biological_process | GSK3B, TP53 |
ER to Golgi vesicle-mediated transport | biological_process | FOLR1, SERPINA1, GAS6, STX5 |
ERBB signaling pathway | biological_process | MAPK1, NRG1 |
ERBB2 signaling pathway | biological_process | SRC, PIK3R1, AKT1, SHC1, ERBB3, PIK3CA, HSP90AA1, EGFR, ERBB2, EGF, NRAS, KRAS, NRG1, PTPRR |
ERK1 and ERK2 cascade | biological_process | MAPK1, PTGER4, OXTR, IGF1, ITGAV, APOA1, LGALS9, EGF, CCL11 |
error-free translesion synthesis | biological_process | PCNA |
error-prone translesion synthesis | biological_process | PCNA |
erythrocyte development | biological_process | BCL6, TMOD3 |
erythrocyte differentiation | biological_process | GATA3, INHBA, BMP4, KIT, CASP3, INHA |
erythrocyte homeostasis | biological_process | AXL, HMOX1 |
erythropoietin-mediated signaling pathway | biological_process | KIT |
establishment of cell polarity | biological_process | GSK3B, WNT7A, PTK2 |
establishment of chromatin silencing | biological_process | SIRT1 |
establishment of chromosome localization | biological_process | BIRC5 |
establishment of endothelial barrier | biological_process | ICAM1, F2RL1 |
establishment of epithelial cell apical/basal polarity | biological_process | WNT5A |
establishment of epithelial cell polarity | biological_process | HES5 |
establishment of Golgi localization | biological_process | CDC42 |
establishment of integrated proviral latency | biological_process | HMGA1, XRCC4 |
establishment of macromolecular complex localization to telomere | biological_process | ATM |
establishment of mitotic spindle orientation | biological_process | SPRY2 |
establishment of nucleus localization | biological_process | PTK2 |
establishment of planar polarity | biological_process | WNT5A, TP63 |
establishment of protein localization | biological_process | ITGA2, PLK1 |
establishment of protein localization to Golgi | biological_process | NRAS |
establishment of protein localization to membrane | biological_process | BRAF |
establishment of protein localization to mitochondrion | biological_process | AKT1 |
establishment of protein localization to plasma membrane | biological_process | CDH1, TNFRSF1A, TNF, LAMA5, WNT4 |
establishment of protein localization to telomere | biological_process | BRCA2, TERT |
establishment of RNA localization to telomere | biological_process | ATM |
establishment of Sertoli cell barrier | biological_process | ICAM1 |
establishment of skin barrier | biological_process | CLDN4, KRT1, TP63 |
establishment of synaptic specificity at neuromuscular junction | biological_process | F2R |
establishment of T cell polarity | biological_process | CCL21, CCL19, CCR7 |
establishment or maintenance of apical/basal cell polarity | biological_process | CDC42 |
establishment or maintenance of cell polarity | biological_process | GSK3B, CTNNA1, CDC42 |
establishment or maintenance of transmembrane electrochemical gradient | biological_process | BAX |
estrogen biosynthetic process | biological_process | CYP19A1, HSD17B1, STAR, HSD17B7 |
estrogen metabolic process | biological_process | HSD17B1, COMT, IL1B, CYP1B1, SULT1E1 |
estrous cycle | biological_process | WNT5A, MMP13, CLU, OPRM1, MMP7, PTN, OXTR, ANXA1, ESR2 |
ethylene metabolic process | biological_process | CYP1A1 |
evasion or tolerance of host defenses by virus | biological_process | TGFB1, SMAD3 |
excitatory postsynaptic potential | biological_process | OPRM1, GHRL |
excitatory synapse assembly | biological_process | WNT5A, WNT7A |
excretion | biological_process | HMOX1, TACR2, AQP2, AQP5 |
execution phase of apoptosis | biological_process | AKT1, CASP3 |
exocrine pancreas development | biological_process | INSR |
exocytosis | biological_process | CCL5, CCL3, CCR1, PAK1 |
exogenous drug catabolic process | biological_process | CYP2A6, CYP2B6, CYP2C19, CYP1A2 |
exosomal secretion | biological_process | COPS5 |
exploration behavior | biological_process | ITGA3, AGTR2 |
extracellular matrix assembly | biological_process | TGFB1, GAS6 |
extracellular matrix constituent secretion | biological_process | CREB3L1 |
extracellular matrix disassembly | biological_process | CDH1, MMP13, MMP9, SPP1, ENG, MMP7, MMP10, CD44, TIMP2, MMP14, CMA1, MMP11, BSG, MMP12, FN1, A2M, TIMP1, MMP1, MMP2, MMP3, CTSG, ADAM8, TPSAB1, LAMC2, HTRA1, DCN, LAMC1 |
extracellular matrix organization | biological_process | CDH1, ITGA6, FGF2, ITGA3, FBLN1, BGN, MMP9, KDR, SPP1, COL4A2, ITGA2, ITGB5, LAMA1, SPARC, CD44, PECAM1, VCAN, VCAM1, ITGB6, MMP11, TNC, BSG, COL18A1, FN1, ITGB3, ITGB1, ITGAV, FGA, TNF, PDGFA, TNFRSF11B, CYR61, LAMA5, SERPINE1, THBS1, ITGB2, COL4A1, ICAM1, COL5A2, TGFB2, PTK2, ATP7A, NFKB2, LOXL1, LAMC2, POSTN, SPOCK2, SMOC2, DCN, LAMC1, CRISPLD2 |
extracellular negative regulation of signal transduction | biological_process | AGTR2, DKK1, ESR2 |
extraocular skeletal muscle development | biological_process | FOXL2 |
extrathymic T cell selection | biological_process | IL15 |
extrinsic apoptotic signaling pathway | biological_process | INHBA, FASLG, TNFRSF1B, IL6R, G0S2, FAS, IL12A, IFNG, TGFB1, TNF, TLR3, IL33, TGFB2, SMAD3, BAX |
extrinsic apoptotic signaling pathway in absence of ligand | biological_process | GSK3B, BCL2, ERBB3, CASP3, KITLG, FAS, ITGAV, IL1A, BCL2L11, IL1B, IL4, BCL2L1, BAX, MCL1, IL2 |
extrinsic apoptotic signaling pathway via death domain receptors | biological_process | BCL2, TNFRSF1A, PIK3R1, FASLG, FAS, NGF, TNF, BAX, DAPK1 |
eye development | biological_process | HMGB1, BMP6, SOX2, BMPR1B, TGFB2 |
eye morphogenesis | biological_process | COL5A2 |
eye photoreceptor cell development | biological_process | VEGFA, PRDM1 |
eye photoreceptor cell differentiation | biological_process | STAT3 |
eyelid development in camera-type eye | biological_process | INHBA, EGFR, JUN, HDAC2, HDAC1, TWIST1 |
face development | biological_process | WNT5A, MAPK1, BRAF |
face morphogenesis | biological_process | TGFB1, CLDN5, DKK1, MMP2, TGFB2, DLX5, CRISPLD2 |
facial nerve structural organization | biological_process | HOXB2, NRP1, SEMA3A |
facioacoustic ganglion development | biological_process | NRP1, SEMA3A |
farnesol catabolic process | biological_process | AKR1C3 |
fat cell differentiation | biological_process | GSK3B, CCND1, HMGA2, ATF2, IL11, CCR2, INSR, GPX1, FOXO1, PLCB1, RETN |
fatty acid alpha-oxidation | biological_process | ALDH3A2 |
fatty acid beta-oxidation | biological_process | LEP, ADIPOQ |
fatty acid biosynthetic process | biological_process | PTGDS, BRCA1, LIPC, PTGS1, PTGS2, PTGES, ACLY, PTGES2 |
fatty acid catabolic process | biological_process | LEP |
fatty acid homeostasis | biological_process | APOE, SIRT1 |
fatty acid metabolic process | biological_process | PTGDS, ALOX15, HPGD, BRCA1, LIPC, PTGS1, PTGS2, C3, PTGES, PPARA, PTGES2, ADIPOR2, ADIPOR1 |
fatty acid oxidation | biological_process | PPARG, ADIPOQ, ADIPOR2, ADIPOR1 |
fatty acid transport | biological_process | PPARA |
Fc receptor mediated inhibitory signaling pathway | biological_process | LILRB1 |
Fc receptor mediated stimulatory signaling pathway | biological_process | FCER1G |
Fc receptor signaling pathway | biological_process | KIT |
Fc-epsilon receptor signaling pathway | biological_process | MAPK1, PIK3R1, SHC1, NFKB1, PIK3CA, FCER1G, PSMD9, JUN, MAP3K7, MAP2K7, FOS, PSMD10, NRAS, KRAS, RAC1, RELA, PAK1 |
Fc-gamma receptor signaling pathway | biological_process | FCER1G |
Fc-gamma receptor signaling pathway involved in phagocytosis | biological_process | CRK, SRC, MAPK1, PIK3R1, PIK3CA, HSP90AA1, FYN, CDC42, RAC1, PTK2, ACTB, PAK1, LIMK1 |
feeding behavior | biological_process | DRD2, FYN, NTRK2, UCN, NPY |
female gamete generation | biological_process | FSHR, GDF9, FSHB, ATM |
female genitalia development | biological_process | SRD5A2, SRD5A1 |
female genitalia morphogenesis | biological_process | TP63 |
female gonad development | biological_process | FSHR, BRCA2, FOXL2, NR5A1, ESR2, SMAD4, AMHR2, WNT4 |
female gonad morphogenesis | biological_process | SMAD4 |
female meiosis chromosome segregation | biological_process | MLH1, PLK1 |
female meiotic division | biological_process | HSF1 |
female pregnancy | biological_process | BCL2, CRHR1, IGFBP2, LEP, HPGD, PTGER4, IGFBP5, ITGA2, CRHBP, STS, IDO1, COMT, OXTR, ADM, PTGER3, IGF1, TGFB1, LGALS9, CLDN4, FOS, FSHB, PRL, IGF2, GC, RLN1, IL4, CRH, PCSK5, UCN, HSD11B2, PAPPA, OVGP1, ADIPOR2 |
female sex determination | biological_process | WNT4 |
female somatic sex determination | biological_process | FOXL2 |
ferrous iron import into cell | biological_process | TF |
fertilization | biological_process | NR2F2, BCL2L1, BAX, NECTIN3 |
fever generation | biological_process | IL1A, IL1B |
fibrinolysis | biological_process | FGA, PLAT, ANXA2, SERPINE1, PLAU, KRT1, SERPINB2, PLAUR, CPB2 |
fibroblast activation | biological_process | IL17A |
fibroblast apoptotic process | biological_process | MYC |
fibroblast growth factor receptor signaling pathway | biological_process | FGFR1, FGF2, MAPK1, FGFR2, TIA1, FGF1 |
fibroblast growth factor receptor signaling pathway involved in hemopoiesis | biological_process | FGFR2 |
fibroblast growth factor receptor signaling pathway involved in mammary gland specification | biological_process | FGFR2 |
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow | biological_process | FGFR2 |
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development | biological_process | FGFR1, FGFR2 |
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow | biological_process | FGFR2 |
fibroblast proliferation | biological_process | EDNRA |
filopodium assembly | biological_process | ITGA6, CDC42 |
flagellated sperm motility | biological_process | SLC26A8 |
flavonoid metabolic process | biological_process | CYP1A1 |
floor plate morphogenesis | biological_process | NODAL |
focal adhesion assembly | biological_process | BCL2, ITGA2, LAMA5 |
folic acid metabolic process | biological_process | FOLR1, MTHFR |
folic acid transport | biological_process | FOLR1 |
folic acid-containing compound metabolic process | biological_process | FOLH1 |
follicle-stimulating hormone signaling pathway | biological_process | FSHR, FSHB |
follicular dendritic cell differentiation | biological_process | NFKB2 |
forebrain anterior/posterior pattern specification | biological_process | WNT1 |
forebrain astrocyte development | biological_process | KRAS |
forebrain cell migration | biological_process | AXL, TYRO3, EMX2 |
forebrain development | biological_process | SRC, NR2F2, BMP4, CTNNB1, NOTCH1, DRD2, SSTR1, SOX2, CCR2, FYN, ARID1A, DKK1, EMX2 |
forebrain morphogenesis | biological_process | PTEN |
forebrain neuron differentiation | biological_process | CSF1R |
forebrain radial glial cell differentiation | biological_process | HES5 |
foregut morphogenesis | biological_process | NOTCH1 |
formaldehyde metabolic process | biological_process | ALDH3A2 |
formation of anatomical boundary | biological_process | SMAD4, NODAL |
formation of radial glial scaffolds | biological_process | ITGB1 |
formation of translation preinitiation complex | biological_process | EIF3E |
frontal suture morphogenesis | biological_process | TGFB1 |
fructose biosynthetic process | biological_process | AKR1B1 |
fungiform papilla formation | biological_process | CTNNB1, HDAC2, HDAC1 |
fusion of virus membrane with host plasma membrane | biological_process | CCR5, CD4, GAS6, CXCR4 |
G-protein coupled acetylcholine receptor signaling pathway | biological_process | PLCB1 |
G-protein coupled receptor internalization | biological_process | DRD2, ADM |
G-protein coupled receptor signaling pathway | biological_process | FSHR, CRHR1, F2R, PPARG, CCL5, IGF2R, CXCL8, OPRM1, AKT1, PTGER4, CCL3, DRD2, FPR1, CCR1, CCR5, CXCR3, AGTR1, AGTR2, EDNRA, CXCL1, CXCR1, CXCR2, CCL2, CXCL2, TACR2, TACR1, LHCGR, OXTR, SSTR1, SSTR5, CCR2, AKR1C3, CXCL5, PTGFR, PTGER3, PTGER2, CXCL12, CCR9, AKR1C2, INSR, LGR5, APOA1, APOE, CXCL10, C3, CCL25, CXCR6, CCL21, CCL22, DEFB4A, CCL16, CXCL13, C5, EDN1, RAC1, CXCR4, F2RL1, GHRL, CCL19, GPER1, UCN, CCL7, CX3CL1, DEFB1, IL2, SST, PLCB3, KISS1R, CXCL6, CRHR2, SFRP4, CCL17, HRH4, LPAR3, CCR7, CCL11, CCR8, ADIPOR2, ADIPOR1, RXFP1 |
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger | biological_process | AGTR2 |
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | biological_process | OPRM1, CCR1, CCL2, LHCGR, SSTR1, SSTR5, ANXA1, LPAR3, NPY |
G1 to G0 transition | biological_process | EZH2 |
G1/S transition of mitotic cell cycle | biological_process | INHBA, CCND1, PCNA, CDKN1B, CDKN1A, CDKN2A, ITGB1, LATS1, RB1, EIF4EBP1, PIM2 |
G2 DNA damage checkpoint | biological_process | BRCA1, PLK1 |
G2/M transition of mitotic cell cycle | biological_process | CCNB1, CDKN1A, CHEK2, AURKA, HSP90AA1, BIRC5, LATS1, ABCB1, PLK1, PLCB1 |
GABAergic neuron differentiation | biological_process | INHBA, GATA2 |
galactose catabolic process | biological_process | PGM1, GALT |
galactose metabolic process | biological_process | GALT |
gamete generation | biological_process | WNT4 |
gamma-delta T cell activation | biological_process | MICA, MICB |
ganglion mother cell fate determination | biological_process | NTF4 |
gap junction assembly | biological_process | GJA1, CTNNA1 |
gastric acid secretion | biological_process | GHRL |
gastric emptying | biological_process | UCN |
gastric motility | biological_process | CRHR2 |
gastrulation | biological_process | CFC1B, SMAD3, SMAD2, SMAD4, NODAL |
gastrulation with mouth forming second | biological_process | CTNNB1, SMAD4, NODAL |
gene expression | biological_process | FAS |
gene silencing | biological_process | DNMT1 |
gene silencing by RNA | biological_process | DICER1, HIST2H3A |
generation of neurons | biological_process | FGFR1, TGFB2 |
generation of ovulation cycle rhythm | biological_process | KISS1 |
generation of precursor metabolites and energy | biological_process | ATP5B, ADIPOQ |
genitalia development | biological_process | WNT5A, HNF1B |
genitalia morphogenesis | biological_process | CTNNB1 |
germ cell development | biological_process | MSH2, BMP4, AKT1, WT1, MTOR, ANGPT2, PRDM1, BCL2L1, BAX |
germ cell migration | biological_process | KIT, ITGB1, TGFB1 |
germinal center B cell differentiation | biological_process | ADA |
germinal center formation | biological_process | BCL6, CXCL13, NFKB2, ADAM17 |
gland morphogenesis | biological_process | BCL2, FGFR2 |
glial cell apoptotic process | biological_process | CASP3, RB1, BAX |
glial cell differentiation | biological_process | NOTCH1, NRG1, PAX2, MMP24 |
glial cell fate commitment | biological_process | SOX2, NRG1, HES5 |
glial cell fate determination | biological_process | CTNNB1 |
glial cell migration | biological_process | CCL2, VCAN, FN1, TGFB2 |
gliogenesis | biological_process | ANXA1, ADAM22 |
glomerular basement membrane development | biological_process | WT1 |
glomerular capillary formation | biological_process | BMP4 |
glomerular endothelium development | biological_process | PECAM1 |
glomerular filtration | biological_process | EDNRA |
glomerular mesangial cell development | biological_process | NOTCH1 |
glomerular mesangial cell proliferation | biological_process | EGR1 |
glomerular parietal epithelial cell differentiation | biological_process | PROM1 |
glomerular visceral epithelial cell development | biological_process | BMP4, JAG1 |
glomerular visceral epithelial cell differentiation | biological_process | WT1, PROM1 |
glomerulus development | biological_process | BCL2, WT1 |
glomerulus vasculature development | biological_process | ANGPT2, ANGPT1 |
glucagon secretion | biological_process | IL6 |
glucocorticoid biosynthetic process | biological_process | HSD3B2, CYP17A1, CYP11A1, CRH, HSD11B2 |
glucocorticoid catabolic process | biological_process | YWHAH |
glucocorticoid mediated signaling pathway | biological_process | SGK1, NR3C1 |
glucocorticoid metabolic process | biological_process | STAR, SERPINA6, APOA1, HSD11B2 |
glucocorticoid receptor signaling pathway | biological_process | ARID1A, NR3C1, YWHAH |
gluconeogenesis | biological_process | PGM1, ENO2, ENO1 |
glucose homeostasis | biological_process | STAT3, PPARG, LEP, AKT1, IGFBP5, USF1, LEPR, SSTR5, INSR, IL6, HIF1A, FOXO1, ADIPOQ, ADIPOR2, ADIPOR1 |
glucose metabolic process | biological_process | PGM1, LEP, AKT1, IGFBP5, USF1, PIK3CA, TNF, IGF2, ADIPOQ, GHRL, IRS2 |
glucose transport | biological_process | AKT1, BRAF, EDNRA, EDN1, NRG1 |
glutamate metabolic process | biological_process | GCLC |
glutamate receptor signaling pathway | biological_process | SSTR1, PLCB1 |
glutamate secretion | biological_process | NTRK2 |
glutathione biosynthetic process | biological_process | GCLC |
glutathione derivative biosynthetic process | biological_process | GSTP1, GSTM1, GSTT1, GSTZ1 |
glutathione metabolic process | biological_process | GCLC, GSTP1, GSTM1, GSTT1, GSTZ1, SOD1, GPX1 |
glycerol biosynthetic process | biological_process | LEP |
glycerol ether metabolic process | biological_process | TXN |
glycerol transport | biological_process | AQP2, AQP8, AQP5 |
glycerophospholipid catabolic process | biological_process | LIPC |
glycerophospholipid metabolic process | biological_process | PEMT |
glycogen biosynthetic process | biological_process | PGM1, AKT1 |
glycogen catabolic process | biological_process | PGM1 |
glycogen cell differentiation involved in embryonic placenta development | biological_process | AKT1 |
glycogen metabolic process | biological_process | GSK3B, AKT1, IL6ST |
glycolate biosynthetic process | biological_process | PARK7 |
glycolate metabolic process | biological_process | IGF1 |
glycolipid biosynthetic process | biological_process | GBGT1 |
glycolytic process | biological_process | PGM1, ENO2, ENO1 |
glycoprotein metabolic process | biological_process | IL1B, AGER |
glycosaminoglycan biosynthetic process | biological_process | SDC4, SDC1, XYLT2 |
glycosaminoglycan catabolic process | biological_process | SDC4, SDC1, HPSE, NAGLU |
glycosaminoglycan metabolic process | biological_process | BGN, SDC4, VCAN, SDC1, DCN |
glycosphingolipid metabolic process | biological_process | KIT, STS, PSAP, BAX, ARSH, SMPD3 |
glyoxal catabolic process | biological_process | PARK7 |
Golgi disassembly | biological_process | STX5 |
Golgi organization | biological_process | CDC42 |
Golgi to plasma membrane transport | biological_process | CCDC22 |
gonad development | biological_process | FSHR, WT1, AMH |
gonadal mesoderm development | biological_process | AMH |
gonadotrophin-releasing hormone neuronal migration to the hypothalamus | biological_process | NRP1, SEMA3A |
granulocyte chemotaxis | biological_process | CCL3, ANXA1 |
granulocyte macrophage colony-stimulating factor biosynthetic process | biological_process | IL18 |
granulosa cell differentiation | biological_process | CAPN5, FOXL2 |
grooming behavior | biological_process | DRD2 |
growth | biological_process | BCL2, INHBA, VEGFA, BMP4, CNTF, BMP6, MTOR, TGFB1, MSTN, TGFB2, BCL2L1 |
growth factor dependent regulation of skeletal muscle satellite cell proliferation | biological_process | FGF2 |
growth hormone receptor signaling pathway | biological_process | STAT3, PIK3R1, PTK2 |
growth hormone secretion | biological_process | GHRH, GHRL |
growth involved in heart morphogenesis | biological_process | NOTCH1 |
growth plate cartilage axis specification | biological_process | STC1 |
growth plate cartilage development | biological_process | MMP13 |
GTP biosynthetic process | biological_process | NME1 |
hair cell differentiation | biological_process | CTNNB1 |
hair cycle | biological_process | PTGS2 |
hair cycle process | biological_process | CTNNB1, CDH3 |
hair follicle development | biological_process | INHBA, EGFR, LGR5, PDGFA, LAMA5, DKK1, TGFB2, RELA, TP63 |
hair follicle morphogenesis | biological_process | BCL2, FGFR2, CTNNB1, NOTCH1, IGFBP5, SNAI1, CDC42, TGFB2, ATP7A, TP63 |
hair follicle placode formation | biological_process | CTNNB1, CDC42, HDAC2, HDAC1 |
halogenated hydrocarbon metabolic process | biological_process | CYP2E1 |
head development | biological_process | EDNRA, DLX5, IL11RA |
head morphogenesis | biological_process | BRAF, DKK1 |
heart contraction | biological_process | ACE, SOD1, GPX1, CDC42 |
heart development | biological_process | GATA3, BMP4, PCNA, ITGA3, PPARG, MMP13, MAPK1, GJA1, SHC1, CTNNB1, ERBB3, NOTCH1, ID1, CASP3, ENG, EDNRA, GATA2, SPARC, TDGF1, WT1, PTN, OXTR, ADM, ERBB2, NRP1, EDN1, PTEN, TGFB2, NRG1, TEK, SMAD2, PPARA, ID2, ATM, PCSK5, NODAL, SEMA3C, GATA5, ADIPOR2 |
heart looping | biological_process | WNT5A, FOLR1, GJA1, NOTCH1, ENG, SMAD3, HIF1A, IHH, NODAL |
heart morphogenesis | biological_process | VEGFA, MTOR, INSR, TGFB2, PTK2 |
heart trabecula formation | biological_process | TEK, HEY1 |
heart trabecula morphogenesis | biological_process | NOTCH1 |
heart valve development | biological_process | PRDM1 |
heart valve morphogenesis | biological_process | MTOR, TGFB2 |
heat acclimation | biological_process | IL1R1 |
helper T cell enhancement of adaptive immune response | biological_process | CD4 |
helper T cell extravasation | biological_process | CCL2 |
hematopoietic progenitor cell differentiation | biological_process | INHBA, BMP4, FST, TGFB1, FSTL3, SMPD3 |
hematopoietic stem cell differentiation | biological_process | ACE |
hematopoietic stem cell homeostasis | biological_process | TET2 |
hematopoietic stem cell migration | biological_process | KIT |
hematopoietic stem cell migration to bone marrow | biological_process | GAS6 |
hematopoietic stem cell proliferation | biological_process | WNT5A, WNT1 |
heme catabolic process | biological_process | HMOX1, HMOX2 |
heme metabolic process | biological_process | HMOX1, HPX |
heme oxidation | biological_process | HMOX1, HMOX2 |
heme transport | biological_process | HPX, ABCG2 |
hemidesmosome assembly | biological_process | ITGA6, LAMC2, LAMC1 |
hemoglobin biosynthetic process | biological_process | INHBA, INHA, HIF1A |
hemoglobin metabolic process | biological_process | HPX, CAT, TET2 |
hemopoiesis | biological_process | BCL2, IL10, KIT, CTNNB1, CSF1, BRCA2, GATA2, FLT3, MEIS1, CSF1R, RUNX3, TGFB2, JAG1, ANGPT1, NOTCH4, TET2 |
hemostasis | biological_process | F2R, F3, ANXA5, FGA, SERPINA1, PLAU, CPB2 |
heparan sulfate proteoglycan biosynthetic process | biological_process | LIPC, XYLT2 |
heparan sulfate proteoglycan catabolic process | biological_process | HPSE |
heparin biosynthetic process | biological_process | XYLT2, ANGPT1 |
hepatic immune response | biological_process | IL6R, IL6 |
hepatoblast differentiation | biological_process | HNF1B |
hepatocyte apoptotic process | biological_process | FAS, RB1, BCL2L1, DNMT3A |
hepatocyte differentiation | biological_process | ITGA2, HNF1B, ANXA1, WNT1, CYP1A1 |
hepatocyte growth factor receptor signaling pathway | biological_process | MET, HGF, NRP1, MST1R, MST1 |
hepatocyte proliferation | biological_process | MKI67 |
hepoxilin biosynthetic process | biological_process | ALOX15 |
heterochromatin assembly | biological_process | HMGA2 |
heterochromatin maintenance | biological_process | MTHFR |
heterocycle metabolic process | biological_process | CYP2C19, CYP2E1, CYP1A2, CYP1A1 |
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | biological_process | VCAM1, SELP, SELE, ICAM1, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
heterotypic cell-cell adhesion | biological_process | ITGB3, ITGB1, ITGAV, ITGB2 |
high-density lipoprotein particle assembly | biological_process | APOA1, APOA2, APOE |
high-density lipoprotein particle clearance | biological_process | APOA1, APOA2, APOE, SCARB1 |
high-density lipoprotein particle remodeling | biological_process | CETP, LIPC, APOA1, APOA2, APOE, SCARB1 |
hindbrain development | biological_process | CTNNB1, HNF1B, PTN |
hindgut morphogenesis | biological_process | WNT5A |
hindlimb morphogenesis | biological_process | TWIST1 |
hippo signaling | biological_process | YAP1, CASP3, LATS1 |
hippocampus development | biological_process | GSK3B, NME1, CASP3, MDK, SRD5A2, CYP17A1, EZH2, SRD5A1 |
histamine secretion | biological_process | EDNRA, ADA, EDN1 |
histone acetylation | biological_process | ATF2, CLOCK, KAT2B |
histone deacetylation | biological_process | HDAC2, HDAC1, SIRT1 |
histone H2A-S139 phosphorylation | biological_process | HMGA2 |
histone H3 acetylation | biological_process | BRCA2, MAP3K7, KAT2B |
histone H3 deacetylation | biological_process | HDAC2, HDAC1, SIRT1 |
histone H3-K27 methylation | biological_process | EZH2, EHMT2 |
histone H3-K27 trimethylation | biological_process | CHD5 |
histone H3-K4 trimethylation | biological_process | TET3, TET2 |
histone H3-K9 acetylation | biological_process | KAT2B |
histone H3-K9 deacetylation | biological_process | SIRT1 |
histone H3-K9 dimethylation | biological_process | SUV39H1, SUV39H2 |
histone H3-K9 methylation | biological_process | EHMT2 |
histone H3-K9 modification | biological_process | SIRT1 |
histone H3-K9 trimethylation | biological_process | SUV39H1, SUV39H2 |
histone H3-S10 phosphorylation involved in chromosome condensation | biological_process | CCNB1 |
histone H3-T6 phosphorylation | biological_process | PRKCB |
histone H4 acetylation | biological_process | BRCA2, CHD5 |
histone H4 deacetylation | biological_process | HDAC2, HDAC1 |
histone lysine methylation | biological_process | SUV39H1, EHMT2, SUV39H2 |
histone methylation | biological_process | EZH2, EHMT2 |
histone mRNA catabolic process | biological_process | ATM |
histone phosphorylation | biological_process | ATM |
histone-serine phosphorylation | biological_process | AURKA |
homeostasis of number of cells | biological_process | GATA3, RASSF2, BAX, CCR7, TET2 |
homeostasis of number of cells within a tissue | biological_process | BCL2, F2R, CSF1, GATA2, KRAS, RAC1, BAX, IL20RB |
homeostatic process | biological_process | ANG, NR5A2 |
homocysteine metabolic process | biological_process | MTHFR |
homologous chromosome orientation involved in meiotic metaphase I plate congression | biological_process | BRCA2 |
homologous chromosome segregation | biological_process | MLH1, PLK1 |
homophilic cell adhesion via plasma membrane adhesion molecules | biological_process | CDH1, CDH3, ITGB1, PCDH17, NECTIN1, NECTIN3, CADM1, TRO, NECTIN4, CADM2 |
hormone biosynthetic process | biological_process | CYP17A1 |
hormone catabolic process | biological_process | ACE |
hormone metabolic process | biological_process | LEP, CRHBP, NR5A1, WNT4 |
hormone secretion | biological_process | ADM |
hormone-mediated apoptotic signaling pathway | biological_process | CRH, SST |
hormone-mediated signaling pathway | biological_process | FSHR, CRHBP, LHCGR, LATS1, NR5A2, NR5A1, GHRL, CRHR2, ADIPOR2, ADIPOR1 |
humoral immune response | biological_process | BCL2, GATA3, NOTCH1, CCL2, IFNG, LTF, TNF, TNFRSF21, LTA, IL6, CD83 |
humoral immune response mediated by circulating immunoglobulin | biological_process | HLA-DRB1 |
hyaluronan biosynthetic process | biological_process | IL1B |
hyaluronan catabolic process | biological_process | FGF2, CD44, TGFB1 |
hyaluronan metabolic process | biological_process | AKT1, HGF, IL15, MKI67 |
hydrogen ion transmembrane transport | biological_process | MT-CO2 |
hydrogen peroxide biosynthetic process | biological_process | SOD1, CYP1A2, CYP1A1 |
hydrogen peroxide catabolic process | biological_process | PRDX6, GPX3, LPO, GPX1, CAT, MPO |
hydrogen peroxide metabolic process | biological_process | PARK7 |
hypermethylation of CpG island | biological_process | GSK3B, DNMT3A |
hyperosmotic response | biological_process | TLR3, RAC1, SST |
hypochlorous acid biosynthetic process | biological_process | MPO |
hypomethylation of CpG island | biological_process | PIK3CA |
hypophysis morphogenesis | biological_process | WNT5A |
hypothalamus development | biological_process | SRD5A2, CRH, BAX, ESR2, CRHR2, SRD5A1 |
hypotonic response | biological_process | ITGA2 |
hypoxanthine biosynthetic process | biological_process | ADA |
hypoxanthine salvage | biological_process | ADA |
hypoxia-inducible factor-1alpha signaling pathway | biological_process | HIF1A |
I-kappaB kinase/NF-kappaB signaling | biological_process | TNFRSF1A, NFKB1, MAP3K7, TNF, TLR4, TLR3, NFKB2 |
I-kappaB phosphorylation | biological_process | MAP3K7, TLR2, TLR4, TLR3, TLR9 |
icosanoid biosynthetic process | biological_process | PLA2G4A |
icosanoid metabolic process | biological_process | PLA2G4A |
immature B cell differentiation | biological_process | KIT |
immature T cell proliferation in thymus | biological_process | WNT4 |
immune response | biological_process | CRHR1, CD40LG, TNFRSF1A, CCL5, CD36, IL10, CXCL8, PTGER4, CCL3, TNFSF10, NOTCH1, FASLG, CCR1, CCR5, TNFRSF1B, CD40, HLA-DRB1, CXCL1, IL1R1, HLA-C, AZGP1, FAS, CCL2, HLA-E, IL15, LIF, IL9, CTLA4, HLA-G, IL1RN, IL1R2, CXCL2, BMP6, CMA1, KIR2DL1, KIR2DL3, IL12A, HLA-A, IL13, ZEB1, CCR2, CXCL5, KIR3DL1, CXCL12, CCR9, IFNG, IGF1R, IL1A, TNF, CXCL10, C3, TLR2, TLR4, CD4, CCL25, TNFRSF11B, CCL21, CCL22, SLPI, DEFB4A, CCL16, THBS1, CXCL13, TNFRSF21, IL1B, CXCL14, PNP, LTA, IL2RA, HLA-B, HLA-DQA1, CSF2, CD74, HLA-DPB1, IL4, IL5, IL6, CTSG, C1QBP, SMAD3, IL18, CCL19, NECTIN1, TNFSF13B, IL1RL1, IL24, MICA, IL23A, CCL7, CX3CL1, DEFB1, IL2, CXCL6, HAMP, IL10RB, IL16, KIR2DS5, IL17A, MICB, IL22, CCL17, SEMA3C, ULBP2, IL1RAP, IL37, CCL27, HLA-DRA, CD1A, CCR7, CCL11, CCR8, KIR3DS1 |
immune response to tumor cell | biological_process | MICA |
immune response-activating cell surface receptor signaling pathway | biological_process | MICB |
immune response-inhibiting cell surface receptor signaling pathway | biological_process | HLA-G, LILRB1 |
immune response-inhibiting signal transduction | biological_process | IL20RB |
immune response-regulating cell surface receptor signaling pathway | biological_process | CD40 |
immune system development | biological_process | BCL2, SMAD3 |
immune system process | biological_process | SRC, GATA3, BCL6, HMGB1, LGALS3, CLU, MIF, MBL2, CSF1, CD40, AXL, HLA-DRB1, C4A, HLA-C, CD79A, HLA-E, IDO1, CTLA4, HLA-G, HLA-A, ANXA1, FGA, PRKCB, LTF, C3, LGALS9, TLR2, TLR4, CD4, FYN, SLPI, TLR3, TNFRSF21, HP, C5, IL2RA, HLA-B, HLA-DQA1, C4BPA, CD74, HLA-DPB1, CSF1R, C1QBP, F2RL1, TLR9, NOD2, TNFSF13B, MST1R, NOD1, PTPN22, GPER1, CADM1, MICA, IL23A, IL2, MICB, IL27, ISG20, IL1RAP, HLA-DRA, CD1A, KLRK1, LILRB1 |
immunoglobulin mediated immune response | biological_process | FCER1G, CD74 |
immunoglobulin production | biological_process | FAS |
immunoglobulin production involved in immunoglobulin mediated immune response | biological_process | HLA-DRB1 |
immunoglobulin secretion | biological_process | CD40LG |
immunological synapse formation | biological_process | CCL21, CCL19 |
in utero embryonic development | biological_process | MSH2, FGFR1, GATA3, VEGFA, NR2F2, FGFR2, GJA1, CTNNB1, CCNB1, NOTCH1, EDNRA, NOS3, HSD17B2, ITGB1, ENO1, BCL2L11, PRDM1, ADA, C5, EDN1, SMAD3, BCL2L1, HSF1, SMAD2, ATP7A, RARRES2, SMAD4, TWIST1, GATA6, PTPRR, ANGPT1, NODAL |
inactivation of MAPK activity | biological_process | DUSP2 |
inactivation of MAPKK activity | biological_process | IGF1R |
induction by virus of host cell-cell fusion | biological_process | CD4 |
induction of bacterial agglutination | biological_process | FGA |
induction of positive chemotaxis | biological_process | VEGFA, CXCL8, VEGFC, CXCL12, FIGF, IL16 |
inflammatory cell apoptotic process | biological_process | FASLG, FAS, IFNG |
inflammatory response | biological_process | BCL6, CD40LG, F2R, TNFRSF1A, CCL5, HMGB1, ALOX15, CHI3L1, IL10, KIT, CXCL8, MIF, AKT1, CCL3, NFKB1, SPP1, CSF1, CCR1, CCR5, CXCR3, TNFRSF1B, CD40, AXL, AGTR2, CRHBP, CXCL1, C4A, CXCR1, CXCR2, FAS, CCL2, IL15, IDO1, IL9, SELP, SELE, ITGB6, SDC1, CXCL2, TACR1, BMP6, IGFBP4, PTGS1, PTX3, IL13, PTGS2, CCR2, CXCL5, TGFB1, ANXA1, IL1A, TNF, CXCL10, C3, LGALS9, TLR2, TLR4, CCL25, BMPR1B, TNFRSF11B, CXCR6, CCL21, CRP, CCL22, FOS, TLR3, CCL16, THBS1, CXCL13, TNFRSF21, IL1B, ITGB2, C5, IL2RA, IL5, IL6, CRH, CSF1R, RAC1, RELA, PARK7, NTRK2, CXCR4, F2RL1, TLR9, NFE2L2, AIF1, IL18, CCL19, NFKB2, RARRES2, NOD1, AGER, GPER1, ADAM8, IL24, UCN, IL23A, CCL7, CXCL6, IL10RB, IL17A, IL22, IL27, CCL17, IL17F, HRH4, IL1RAP, IL37, CHST2, CCR7, CCL11 |
inflammatory response to antigenic stimulus | biological_process | HMGB1, NOTCH1, HLA-DRB1, CCR2, IL2RA, IL20RB |
inhibition of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | BIRC5 |
inhibition of neuroepithelial cell differentiation | biological_process | NODAL |
inhibitory postsynaptic potential | biological_process | CX3CL1 |
inhibitory synapse assembly | biological_process | WNT5A |
innate immune response | biological_process | SRC, GATA3, PPARG, HMGB1, LGALS3, CLU, MIF, NFKB1, MBL2, CSF1, AXL, JAK1, TYK2, C4A, SAA1, HLA-E, PTX3, FCER1G, KIR2DS4, ANG, ANXA1, FGA, C3, TLR2, TLR4, FYN, SLPI, DEFB4A, TLR3, C5, APCS, C4BPA, CSF1R, C1QBP, PTK2, F2RL1, TLR9, NOD2, NFKB2, MST1R, NOD1, AGER, GPER1, KLRD1, IL23A, DEFB1, KIR2DS5, IL27, ISG20, IL1RAP, NPY, KLRK1, KIR3DS1 |
innate immune response in mucosa | biological_process | NOS2, LTF, IL4, DEFB1 |
inner cell mass cell differentiation | biological_process | HNF1B, TET1 |
inner cell mass cell fate commitment | biological_process | LATS1 |
inner cell mass cell proliferation | biological_process | BRCA2 |
inner cell mass cellular morphogenesis | biological_process | LATS1 |
inner ear development | biological_process | CDKN1B, SPARC, SOX2, TGFB1, LGR5, PDGFA, CXCL14, JAG1, MAF |
inner ear morphogenesis | biological_process | FGFR1, GATA3, WNT5A, FGFR2, GATA2, SPRY2, WNT1, PAX2, DLX5 |
inner ear receptor cell development | biological_process | NAGLU |
inner ear receptor cell differentiation | biological_process | BMP4 |
inner ear receptor stereocilium organization | biological_process | SDC4, HES5 |
inner medullary collecting duct development | biological_process | AKR1B1 |
inner mitochondrial membrane organization | biological_process | BAX |
innervation | biological_process | NTF4 |
inosine biosynthetic process | biological_process | ADA |
inosine catabolic process | biological_process | PNP |
inositol phosphate biosynthetic process | biological_process | FGF2 |
inositol phosphate dephosphorylation | biological_process | PTEN |
inositol phosphate metabolic process | biological_process | PLCD1, PTEN, PLCB1, PLCB3, PLCD3 |
inositol phosphate-mediated signaling | biological_process | EDN1 |
insecticide metabolic process | biological_process | STAR, CYP1A1 |
insulin receptor signaling pathway | biological_process | PIK3R1, AKT1, SHC1, IGFBP1, INSR, IGF1R, IGF2, FOXO1, EIF4EBP1, IRS2 |
insulin receptor signaling pathway via phosphatidylinositol 3-kinase | biological_process | PIK3CA, IGF2 |
insulin secretion | biological_process | LEP, IL1RN, HNF1B, ANXA1, SMAD2 |
insulin-like growth factor receptor signaling pathway | biological_process | IGF2R, PIK3R1, AKT1, IGF1, IGF1R, PLCB1 |
integrin activation | biological_process | FN1, CX3CL1 |
integrin-mediated signaling pathway | biological_process | SRC, ITGA6, ITGA3, FBLN1, ITGA2, ITGB5, ITGB6, FCER1G, ITGB3, ITGB1, ITGAV, APOA1, LAMA5, ITGB2, PTK2 |
intein-mediated protein splicing | biological_process | IHH |
interaction with symbiont | biological_process | GPX1 |
interferon-gamma biosynthetic process | biological_process | IL12B, IL18 |
interferon-gamma production | biological_process | TLR4, LILRB1 |
interferon-gamma secretion | biological_process | GATA3, F2RL1, LILRB1 |
interferon-gamma-mediated signaling pathway | biological_process | HLA-DRB1, JAK1, HLA-C, CD44, NCAM1, HLA-E, VCAM1, HLA-G, HLA-A, IFNG, HLA-B, HLA-DQA1, ICAM1, HLA-DPB1, HLA-DRA |
interleukin-1 alpha secretion | biological_process | S100A13 |
interleukin-1 beta biosynthetic process | biological_process | CMA1 |
interleukin-1 beta production | biological_process | CASP1, IL1B |
interleukin-1 beta secretion | biological_process | CD36, TLR4, F2RL1 |
interleukin-1-mediated signaling pathway | biological_process | EGR1, IL1R1, PLCB1 |
interleukin-10 production | biological_process | TLR2 |
interleukin-10 secretion | biological_process | F2RL1 |
interleukin-11-mediated signaling pathway | biological_process | IL6ST |
interleukin-12 secretion | biological_process | CCL19, CCR7 |
interleukin-12-mediated signaling pathway | biological_process | PLCB1 |
interleukin-13 biosynthetic process | biological_process | IL18 |
interleukin-15-mediated signaling pathway | biological_process | PLCB1 |
interleukin-2 biosynthetic process | biological_process | IL18 |
interleukin-2 production | biological_process | STOML2 |
interleukin-2 secretion | biological_process | PNP |
interleukin-2-mediated signaling pathway | biological_process | JAK1, IL2RB, IL2RA |
interleukin-21 secretion | biological_process | FOXP1 |
interleukin-27-mediated signaling pathway | biological_process | IL6ST |
interleukin-3-mediated signaling pathway | biological_process | CSF2RB |
interleukin-33-mediated signaling pathway | biological_process | IL1RL1 |
interleukin-4 secretion | biological_process | GATA3, NOTCH1 |
interleukin-4-mediated signaling pathway | biological_process | STAT6 |
interleukin-5-mediated signaling pathway | biological_process | CSF2RB |
interleukin-6 secretion | biological_process | NOS2, LEP |
interleukin-6-mediated signaling pathway | biological_process | STAT3, IL6R, IL6ST, IL6, SMAD4 |
interleukin-8 biosynthetic process | biological_process | NOD1 |
interleukin-8 secretion | biological_process | NOS2, CHI3L1, LEP |
interleukin-8-mediated signaling pathway | biological_process | CXCR1, CXCR2 |
intermediate filament organization | biological_process | VIM |
intermediate filament-based process | biological_process | VIM |
intermediate mesodermal cell differentiation | biological_process | BMP4 |
intermediate-density lipoprotein particle remodeling | biological_process | LIPC |
internal peptidyl-lysine acetylation | biological_process | KAT2B |
intestinal absorption | biological_process | CD36, LEP, VDR, SCARB1 |
intestinal cholesterol absorption | biological_process | CD36, AKR1C1 |
intestinal epithelial cell development | biological_process | PRDM1 |
intestinal epithelial cell differentiation | biological_process | GATA6, GATA5 |
intestinal epithelial cell maturation | biological_process | CDKN1A, HIF1A |
intestinal epithelial structure maintenance | biological_process | TLR4 |
intestine smooth muscle contraction | biological_process | TACR2, PTGER3 |
intra-S DNA damage checkpoint | biological_process | MSH2, ATF2 |
intracellular cholesterol transport | biological_process | STAR |
intracellular estrogen receptor signaling pathway | biological_process | SRC, ESR1, ARID1A, ESR2 |
intracellular pH elevation | biological_process | CFTR |
intracellular protein transport | biological_process | PDCD6, CD74, YWHAH, STX5, CSE1L, IPO13 |
intracellular receptor signaling pathway | biological_process | STAT3, NR2F2, AR, AHR, FLT1, ARNT, PTGER3, NR5A2, NR5A1, PPARA |
intracellular signal transduction | biological_process | GSK3B, SRC, MAPK1, KIT, LEP, CXCL8, AKT1, SHC1, DRD2, CASP3, PLCD1, BRAF, AGTR2, JAK1, IGFBP5, TYK2, CXCL1, HMOX1, STMN1, PRKCB, HSPB1, FYN, SGK1, SMAD7, SOCS3, KALRN, EDN1, RAC1, NRG1, PLCB1, TEK, SMAD2, NOD2, NOD1, SMAD4, DAPK1, PLCB3, KSR1, PLCD3 |
intracellular steroid hormone receptor signaling pathway | biological_process | ESR1, ESR2, GPER1 |
intracellular transport | biological_process | APOE |
intramembranous ossification | biological_process | MMP2 |
intrinsic apoptotic signaling pathway | biological_process | MSH6, CLU, CDKN1A, TP53, BAX |
intrinsic apoptotic signaling pathway by p53 class mediator | biological_process | TP53, BAX, FHIT |
intrinsic apoptotic signaling pathway in response to DNA damage | biological_process | MSH2, MSH6, MLH1, BCL2, TNFRSF1A, PIK3R1, BRCA1, TNFRSF1B, BRCA2, HMOX1, CHEK2, TNF, BCL2L11, BCL2L1, BAX, MCL1, SIRT1, ATM |
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological_process | MSH2, CDKN1A, BRCA2, TP53, SIRT1, TP63 |
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological_process | GSK3B, BCL2, BAX |
intrinsic apoptotic signaling pathway in response to oxidative stress | biological_process | BCL2, GPX1, CYP1B1 |
intussusceptive angiogenesis | biological_process | CYR61 |
ion homeostasis | biological_process | CRH |
ion transmembrane transport | biological_process | GJA1, CLCN3, AQP2, S100A6, SGK1, ABCC4, AQP8, ATP7A, AQP5 |
ion transport | biological_process | ATP5A1, CFTR, CLCN3, ATP5B, LTF, SLC22A23, CP, TF, ATP7A, SLC26A8, TRPV1, P2RX3, SLCO4A1 |
IRE1-mediated unfolded protein response | biological_process | SHC1 |
IRES-dependent translational initiation | biological_process | EIF4EBP1 |
iris morphogenesis | biological_process | WNT2, HIF1A |
iron assimilation by chelation and transport | biological_process | LTF |
iron ion homeostasis | biological_process | HMOX1, LTF, TF |
iron ion transport | biological_process | TF, NECTIN1 |
isotype switching | biological_process | MSH2, MSH6, MLH1, CD40LG |
isotype switching to IgG isotypes | biological_process | HSPD1 |
JAK-STAT cascade | biological_process | STAT3, PRLR, CCL2, CCR2, SOCS3, STAT4, AGER |
JAK-STAT cascade involved in growth hormone signaling pathway | biological_process | STAT3, MAPK1, PRLR, PRL |
JNK cascade | biological_process | WNT5A, PTGER4, MAP3K7, TNF, MAP2K7, NOD2, NOD1 |
keratan sulfate biosynthetic process | biological_process | PRELP, CHST6, CHST2 |
keratan sulfate catabolic process | biological_process | PRELP |
keratinization | biological_process | CDH3, CDC42 |
keratinocyte development | biological_process | CDC42 |
keratinocyte differentiation | biological_process | YAP1, WNT5A, NOTCH1, CASP3, AKR1C3, ANXA1, LATS1, TP63, JAG1 |
keratinocyte proliferation | biological_process | TP63 |
kidney development | biological_process | BCL2, GATA3, VEGFA, BMP4, MME, CTNNB1, SERPINF1, ACE, AGTR1, AGTR2, WT1, HNF1B, BMP6, CA2, FSTL3, BCL2L11, CAT, BAX, SMAD4, PCSK5, WNT4, DCN, TET2 |
kidney morphogenesis | biological_process | AGTR2, HNF1B, WNT4 |
killing by host of symbiont cells | biological_process | MBL2 |
killing of cells of other organism | biological_process | HAMP |
Kit signaling pathway | biological_process | KIT |
kynurenic acid biosynthetic process | biological_process | IDO1 |
L-ascorbic acid metabolic process | biological_process | GCLC |
L-methionine biosynthetic process from methylthioadenosine | biological_process | ADI1 |
L-phenylalanine catabolic process | biological_process | GSTZ1 |
labyrinthine layer blood vessel development | biological_process | MAPK1, AKT1, WNT2, PLCD1, CYR61, HEY1, PLCD3 |
lacrimal gland development | biological_process | FGFR2 |
lactate biosynthetic process | biological_process | PARK7 |
lactate metabolic process | biological_process | HIF1A |
lactation | biological_process | XDH, CCND1, VEGFA, NME1, VDR, PRLR, OXTR, MT-CO2, PRL, GC, HIF1A, ATP7A, USF2 |
lamellipodium assembly | biological_process | KIT, RAC1 |
late viral transcription | biological_process | USF1, USF2 |
lateral mesoderm development | biological_process | YAP1 |
lateral sprouting from an epithelium | biological_process | FGFR2 |
lateral sprouting involved in mammary gland duct morphogenesis | biological_process | WNT5A |
layer formation in cerebral cortex | biological_process | CTNNB1 |
leading edge cell differentiation | biological_process | JUN |
leading strand elongation | biological_process | PCNA |
learning | biological_process | PTN, COMT, PTGS1, PTGS2, JUN, BCHE, FYN, CLDN5, NTRK2 |
learning or memory | biological_process | CASP3, CRHBP, STS, TACR1, EGFR, IL1B, CRH, PTEN, ESR2, UCN |
left lung morphogenesis | biological_process | NODAL |
left/right axis specification | biological_process | NOTCH1 |
left/right pattern formation | biological_process | SNAI1 |
lens development in camera-type eye | biological_process | GATA3, WNT5A, GJA1, WNT2, CRYAB, MAF |
lens fiber cell development | biological_process | VIM, WNT7A |
lens fiber cell differentiation | biological_process | TGFB1, SMAD3, MAF |
lens induction in camera-type eye | biological_process | BMP4 |
lens morphogenesis in camera-type eye | biological_process | CTNNB1, MEIS1, NECTIN1, NECTIN3 |
leptin-mediated signaling pathway | biological_process | STAT3, LEP, LEPR, SIRT1, ADIPOR1 |
leukemia inhibitory factor signaling pathway | biological_process | IL6ST, LIF, LIFR |
leukocyte activation | biological_process | EDN1 |
leukocyte adhesive activation | biological_process | CX3CL1 |
leukocyte cell-cell adhesion | biological_process | CD40LG, CCL5, VCAM1, SELP, SELE, ITGB1, ITGB2, ICAM1 |
leukocyte chemotaxis | biological_process | IL10, CX3CL1, IL16 |
leukocyte differentiation | biological_process | ID2 |
leukocyte homeostasis | biological_process | BCL2, FLT3, BCL2L11, BAX |
leukocyte migration | biological_process | SRC, ITGA6, ITGA3, PIK3R1, MMP9, MIF, SHC1, CD44, PECAM1, SELP, SELE, PIK3CA, FCER1G, L1CAM, BSG, FN1, ITGB3, ITGB1, ITGAV, TNF, CCL25, FYN, ANGPT2, IL1B, ITGB2, NRAS, KRAS, ICAM1, MMP1, CD74, GAS6, TEK, F2RL1, ANGPT1, GRB14 |
leukocyte migration involved in inflammatory response | biological_process | CCL2, SELE, ITGB2, ADAM8, CX3CL1 |
leukocyte proliferation | biological_process | F2RL1 |
leukocyte tethering or rolling | biological_process | LEP, VCAM1, SELP, SELE, ITGB1, TNF |
leukotriene metabolic process | biological_process | ALOX15 |
Leydig cell differentiation | biological_process | CCND1, CYP17A1 |
limb bud formation | biological_process | FGFR2, SEMA3C |
limb development | biological_process | NR2F2, CTNNB1, GREM1, WNT7A |
limb morphogenesis | biological_process | WNT5A, BMPR1B, BAX, PCSK5 |
lipid biosynthetic process | biological_process | ACLY |
lipid catabolic process | biological_process | AKR1D1, PLA2G4A, PRDX6, PLCD1, LIPC, PLA2G2A, PLCB1, RARRES3, PLA2G16, PLCB3, PAFAH1B2, PLCD3 |
lipid digestion | biological_process | LIPC |
lipid homeostasis | biological_process | CETP, PPARG, USF1, APOE, USF2, IRS2 |
lipid localization | biological_process | STOML2 |
lipid metabolic process | biological_process | ATP5A1, AKR1D1, CETP, NR2F2, PLA2G4A, PTGDS, PPARG, PRDX6, CLU, CD36, ALOX15, LEP, HPGD, BRCA1, PLCD1, STS, LIPC, HSD17B1, PLA2G2A, IL1RN, PTGS1, PON1, SRD5A2, PTGS2, HSD17B3, HSD17B2, AKR1C2, ATP5B, CYP11A1, APOA1, APOE, C3, PTGES, CYP1A2, GPX1, PSAP, PTEN, PLCB1, ACLY, PPARA, RARRES3, PLA2G16, HSD17B7, PLCB3, PAFAH1B2, PTGES2, PLCD3, SRD5A1, ADIPOR2, ADIPOR1, SMPD3, PEMT |
lipid storage | biological_process | CD36, APOA1 |
lipid transport | biological_process | CETP, STAR, APOA1, APOA2, APOE, PSAP, SCARB1, SFTPA1, SLCO2A1 |
lipopolysaccharide transport | biological_process | SCARB1 |
lipopolysaccharide-mediated signaling pathway | biological_process | CCL5, MAPK1, AKT1, CCL3, CCL2, NOS3, TGFB1, TNF, TLR2, TLR4, IL1B, IL18, PTPN22, SCARB1 |
lipoprotein biosynthetic process | biological_process | APOA1, APOA2, APOE |
lipoprotein catabolic process | biological_process | APOE, ATM |
lipoprotein metabolic process | biological_process | CETP, SDC1, APOA1, APOA2, APOE, PPARA, SCARB1 |
lipoprotein transport | biological_process | PPARG, CD36, PRKCB |
lipoxin A4 biosynthetic process | biological_process | ALOX15 |
lipoxin metabolic process | biological_process | HPGD |
lipoxygenase pathway | biological_process | ALOX15, HPGD, PTGS2, GPX1 |
liver development | biological_process | CCND1, IGF2R, CTNNB1, NOTCH1, HGF, LIPC, HNF1B, PTN, PIK3CA, JUN, CP, ADA, CYP1A1, SMAD3, RELA, GATA6, WNT4, NODAL, SRD5A1 |
liver morphogenesis | biological_process | TET2 |
liver regeneration | biological_process | CCND1, FAS, FGA, CPB2 |
localization within membrane | biological_process | RAC1 |
locomotor rhythm | biological_process | PTEN, ID2, NAGLU |
locomotory behavior | biological_process | OPRM1, DRD2, SOD1, MEIS1, PTEN, NRG1, ATP7A |
locomotory exploration behavior | biological_process | CRH |
long term synaptic depression | biological_process | PTEN |
long-chain fatty acid import | biological_process | CD36 |
long-chain fatty acid transport | biological_process | PPARG, APOE |
long-chain fatty-acyl-CoA biosynthetic process | biological_process | ACLY |
long-term memory | biological_process | DRD2, TACR1, MTOR, NTF4, SGK1, NTRK2 |
long-term synaptic potentiation | biological_process | MAPK1, BRAF, PTN, CRH, PTEN, NTRK2, CRHR2 |
loop of Henle development | biological_process | JAG1 |
low-density lipoprotein particle clearance | biological_process | CD36, HMOX1, LIPC, ADIPOQ, SCARB1 |
low-density lipoprotein particle mediated signaling | biological_process | CD36 |
low-density lipoprotein particle receptor biosynthetic process | biological_process | PPARG |
low-density lipoprotein particle remodeling | biological_process | CETP, AGTR1, LIPC, PLA2G2A, APOA2, APOE, MPO |
lung alveolus development | biological_process | BMP4, WNT5A, FGFR2, IGFBP5, LIF, PDGFA, ADA, ATP7A, ERRFI1 |
lung cell differentiation | biological_process | CTNNB1 |
lung development | biological_process | FGFR1, VEGFA, BMP4, WNT5A, ITGA3, FGFR2, HMGB1, CHI3L1, CTNNB1, WNT2, NOTCH1, SPARC, LIF, MMP14, PTN, NOS3, FGF1, FSTL3, CYP1A2, LAMA5, SPRY2, CP, ADA, CRH, EIF4EBP1, SMAD2, AGER, NODAL, CRISPLD2 |
lung epithelial cell differentiation | biological_process | YAP1 |
lung epithelium development | biological_process | ERRFI1 |
lung goblet cell differentiation | biological_process | AGR2 |
lung growth | biological_process | SPRY2 |
lung induction | biological_process | CTNNB1, WNT2 |
lung lobe development | biological_process | BMP4 |
lung lobe morphogenesis | biological_process | FGFR2, LIF |
lung morphogenesis | biological_process | BMP4, MAPK1, ID1, SPRY2 |
lung saccule development | biological_process | GATA6 |
lung vasculature development | biological_process | ID1, LIF, ERRFI1 |
lung-associated mesenchyme development | biological_process | FGFR1, FGFR2, CTNNB1 |
luteinization | biological_process | PDGFRA, CAPN5, NR5A1 |
luteinizing hormone signaling pathway | biological_process | LHCGR |
luteolysis | biological_process | PLA2G4A, MMP13 |
lymph node development | biological_process | IL15, TGFB1, CXCL13, LTA |
lymph vessel development | biological_process | NR2F2, FLT4 |
lymph vessel morphogenesis | biological_process | VEGFA |
lymphangiogenesis | biological_process | FLT4 |
lymphocyte chemotaxis | biological_process | CCL5, CCL3, SAA1, CCL2, CCL25, CCL21, CCL22, CCL16, CCL19, ADAM8, CX3CL1, CCL17, CXCL16, CCL11 |
lymphocyte chemotaxis across high endothelial venule | biological_process | CXCL13 |
lymphocyte homeostasis | biological_process | BCL2, BCL2L11 |
lymphocyte migration | biological_process | GATA3, TBX21 |
lymphocyte migration into lymph node | biological_process | CCR7 |
lymphocyte proliferation | biological_process | FLT3 |
lymphoid progenitor cell differentiation | biological_process | BCL2, BMP4, KIT |
lymphotoxin A biosynthetic process | biological_process | IL17F |
lysosome organization | biological_process | NAGLU |
macroautophagy | biological_process | MTOR, GABARAPL1 |
macrophage activation | biological_process | TLR4, CSF2, FOXP1 |
macrophage activation involved in immune response | biological_process | HMGB1 |
macrophage chemotaxis | biological_process | CCL5, LGALS3, CCL3, SAA1, CCL2, CX3CL1 |
macrophage colony-stimulating factor signaling pathway | biological_process | CSF1, CSF1R, MST1R |
macrophage cytokine production | biological_process | GAS6, SIRT1 |
macrophage derived foam cell differentiation | biological_process | TGFB1 |
macrophage differentiation | biological_process | VEGFA, BMP4, MMP9, CSF1, CSF1R, CDC42, SIRT1 |
macrophage migration inhibitory factor signaling pathway | biological_process | CD74 |
maintenance of chromatin silencing | biological_process | ARID1A, HDAC2, SIRT1 |
maintenance of DNA methylation | biological_process | DNMT1 |
maintenance of DNA repeat elements | biological_process | MSH2, MSH6 |
maintenance of gastrointestinal epithelium | biological_process | TLR9, NOD2, MUC4 |
maintenance of location in cell | biological_process | APOE |
maintenance of mitotic sister chromatid cohesion | biological_process | RB1 |
maintenance of permeability of blood-brain barrier | biological_process | PTGS1, PTGS2 |
maintenance of protein location in cell | biological_process | CD4 |
maintenance of protein location in mitochondrion | biological_process | AKT1 |
maintenance of protein location in nucleus | biological_process | NR5A1 |
male genitalia development | biological_process | CTNNB1, WT1, BMP6, LHCGR, SRD5A2, HSD17B3, SRD5A1 |
male gonad development | biological_process | MSH2, BCL2, GATA3, INHBA, FSHR, WNT5A, KIT, CTNNA1, KITLG, MMP14, HOXA10, WT1, LHCGR, SRD5A2, HOXA11, AKR1C3, STAR, ESR1, INSR, CYP17A1, INHA, FSTL3, SOX15, TLR3, BCL2L11, LHB, BCL2L1, BAX, NR5A1, ESR2, SMAD4, AMHR2, GATA6, WNT4, SRD5A1 |
male mating behavior | biological_process | PTEN |
male meiosis | biological_process | MLH1, PIM2 |
male meiosis chromosome segregation | biological_process | MLH1 |
male meiosis I | biological_process | BRCA2 |
male sex determination | biological_process | INSR |
male sex differentiation | biological_process | FKBP4 |
mammary duct terminal end bud growth | biological_process | CSF1, CCL11 |
mammary gland alveolus development | biological_process | CCND1, VEGFA, PRLR, ESR1, EGF, ID2 |
mammary gland branching involved in pregnancy | biological_process | VDR, ESR1 |
mammary gland branching involved in thelarche | biological_process | WNT5A, TGFB1 |
mammary gland bud formation | biological_process | FGFR2 |
mammary gland development | biological_process | NME1, BRCA2, ITGA2, TDGF1, TGFB1, BCL2L11, NRG1, IRS2, NOTCH4 |
mammary gland duct morphogenesis | biological_process | CSF1R |
mammary gland epithelial cell differentiation | biological_process | AKT1, PRLR |
mammary gland epithelial cell proliferation | biological_process | CCND1, MAPK1, STAT6, ID2 |
mammary gland epithelium development | biological_process | WNT2, PRLR, WNT4 |
mammary gland fat development | biological_process | CSF1 |
mammary gland formation | biological_process | BMP4 |
mammary gland involution | biological_process | IGFBP5 |
mammary gland morphogenesis | biological_process | STAT6 |
MAPK cascade | biological_process | FGFR1, FGF2, CCL5, MAPK1, FGFR2, KIT, SHC1, CCL3, ERBB3, CCR5, CSF2RB, BRAF, PDGFRA, JAK1, KITLG, CCL2, NCAM1, IL2RB, PSMD9, EGFR, FGF1, TGFB1, TNF, MYC, PDGFA, ERBB2, FYN, PSMD10, IL1B, EGF, NRAS, KRAS, IL2RA, CSF2, IL5, PTK2, NRG1, TEK, PAK1, IL18, IRS2, IL2, ANGPT1, KSR1 |
MAPK import into nucleus | biological_process | MAPK1 |
mast cell activation | biological_process | FCER1G |
mast cell chemotaxis | biological_process | KIT, RAC1, CCL11 |
mast cell cytokine production | biological_process | KIT |
mast cell degranulation | biological_process | KIT, GATA2, S100A13 |
mast cell differentiation | biological_process | GATA3, KIT |
mast cell proliferation | biological_process | KIT |
maternal aggressive behavior | biological_process | CRHBP |
maternal behavior | biological_process | OXTR, PTEN, MBD2 |
maternal placenta development | biological_process | NR2F2, AKT1, PRDM1, NODAL |
maternal process involved in female pregnancy | biological_process | AKR1B1, ITGA3, MMP7, FAS, CCL2, LIF, MTOR, ITGB1, LGALS9, ANGPT2, HIF1A, IHH |
maternal process involved in parturition | biological_process | PTGER4, EDNRA, CCL2, OXTR, PTGER3, CYP1A1, EDN1, NODAL |
mature conventional dendritic cell differentiation | biological_process | LGALS9, F2RL1, CCL19, CCR7 |
mature ribosome assembly | biological_process | C1QBP |
mechanoreceptor differentiation | biological_process | NTF4, NTRK2 |
megakaryocyte development | biological_process | KIT, MEIS1 |
megakaryocyte differentiation | biological_process | IL11 |
meiosis I | biological_process | BCL2L11 |
meiotic cell cycle | biological_process | H2AFX, AURKA, SLC26A8 |
meiotic chromosome segregation | biological_process | MLH1 |
meiotic DNA recombinase assembly | biological_process | XRCC3 |
meiotic gene conversion | biological_process | MSH2 |
meiotic metaphase I plate congression | biological_process | MLH1 |
meiotic mismatch repair | biological_process | MSH2, MSH6 |
meiotic nuclear division | biological_process | MLH1, MKI67, AURKA |
meiotic spindle midzone assembly | biological_process | MLH1 |
meiotic spindle organization | biological_process | AURKA |
meiotic telomere clustering | biological_process | MLH1, ATM |
melanin metabolic process | biological_process | BCL2 |
melanocyte adhesion | biological_process | KIT |
melanocyte differentiation | biological_process | BCL2, KIT |
melanocyte migration | biological_process | KIT |
melanocyte proliferation | biological_process | WNT5A |
membrane budding | biological_process | ANXA2 |
membrane depolarization | biological_process | JUN, EDN1, PARK7, ADIPOQ |
membrane depolarization during action potential | biological_process | YWHAH |
membrane hyperpolarization | biological_process | CFTR, CASP1, PARK7, ADIPOQ |
membrane lipid catabolic process | biological_process | CYP1B1 |
membrane organization | biological_process | YWHAH |
membrane protein ectodomain proteolysis | biological_process | ADAM17 |
membrane protein intracellular domain proteolysis | biological_process | NFKB1, RELA, ADAM17 |
membrane raft assembly | biological_process | ANXA2 |
membrane to membrane docking | biological_process | VCAM1, ICAM1 |
membranous septum morphogenesis | biological_process | FGFR2, ID2 |
memory | biological_process | ITGA3, SLC6A4, PTGS1, OXTR, PTGS2, IGF1, IL1B, IGF2, PTEN, PLCB1, KAT2B |
menstruation | biological_process | FOXL2 |
mesangial cell-matrix adhesion | biological_process | CCL21 |
mesenchymal cell development | biological_process | BCL2, NOTCH1 |
mesenchymal cell differentiation | biological_process | FGFR1, HMGA2, FGFR2 |
mesenchymal cell differentiation involved in kidney development | biological_process | BMP4 |
mesenchymal cell differentiation involved in lung development | biological_process | FGFR2 |
mesenchymal cell differentiation involved in renal system development | biological_process | BMP4 |
mesenchymal cell proliferation involved in lung development | biological_process | FGFR2, CTNNB1 |
mesenchymal cell proliferation involved in ureter development | biological_process | BMP4 |
mesenchymal cell proliferation involved in ureteric bud development | biological_process | BMP4 |
mesenchymal to epithelial transition | biological_process | GATA3, WT1, PAX2, WNT4 |
mesenchymal to epithelial transition involved in metanephros morphogenesis | biological_process | BMP4, GREM1, PAX2 |
mesenchymal-epithelial cell signaling | biological_process | WNT5A |
mesenchymal-epithelial cell signaling involved in prostate gland development | biological_process | TNC |
mesendoderm development | biological_process | NODAL |
mesoderm development | biological_process | VEGFA, SNAI1, SMAD4 |
mesoderm formation | biological_process | INHBA, BMP4, SNAI1, DKK1, SMAD3, SMAD2, NODAL |
mesodermal cell differentiation | biological_process | INHBA, BMP4, HMGA2, ITGA3, FGFR2, ITGA2, ITGB3, ITGB1 |
mesodermal cell fate determination | biological_process | BMP4 |
mesodermal cell fate specification | biological_process | HOXA11, PAX2 |
mesodermal to mesenchymal transition involved in gastrulation | biological_process | WNT5A |
mesodermal-endodermal cell signaling | biological_process | HMGA2 |
mesonephric duct development | biological_process | HNF1B |
mesonephric duct formation | biological_process | HNF1B |
mesonephric epithelium development | biological_process | FGF1 |
mesonephric tubule development | biological_process | HNF1B, WNT4 |
mesonephros development | biological_process | GATA3, BMP4, PAX2, WNT4 |
metabolic process | biological_process | PLA2G4A, PRDX6, MTHFR, STS, GSTP1, GSTM1, NAT2, HSD3B2, TYMP, ALDH3A2, GSTZ1, CYP26A1, AMY2A, PAK1, ACLY, NAGLU, FOLH1, ARSH, OGG1 |
metal ion transport | biological_process | ATP7A |
metanephric collecting duct development | biological_process | BMP4, AQP2, PAX2 |
metanephric distal convoluted tubule development | biological_process | PAX2 |
metanephric epithelium development | biological_process | WT1, PAX2 |
metanephric glomerular capillary formation | biological_process | PDGFRA |
metanephric mesenchymal cell differentiation | biological_process | PAX2, WNT4 |
metanephric mesenchyme development | biological_process | WT1, PAX2 |
metanephric mesenchyme morphogenesis | biological_process | SMAD4 |
metanephric nephron development | biological_process | WNT4 |
metanephric nephron morphogenesis | biological_process | WNT4 |
metanephric nephron tubule formation | biological_process | PAX2 |
metanephric nephron tubule morphogenesis | biological_process | HES5 |
metanephric S-shaped body morphogenesis | biological_process | WT1 |
metanephric tubule formation | biological_process | WNT4 |
metanephros development | biological_process | BCL2, BMP4, HOXA11, ID2, WNT4 |
metanephros morphogenesis | biological_process | CTNNB1 |
metencephalon development | biological_process | WNT1 |
methionine biosynthetic process | biological_process | ADI1 |
methionine metabolic process | biological_process | MTHFR |
methylation | biological_process | DNMT1, COMT, MAT2A, SUV39H1, CYP1A2, PRDM1, DNMT3A, EZH2, EHMT2, DNMT3B, SUV39H2, PEMT |
methylation-dependent chromatin silencing | biological_process | DNMT3A, SIRT1, MBD2 |
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione | biological_process | PARK7 |
microglial cell activation | biological_process | CLU, IL13, JUN, TLR3, IL4, AIF1, CX3CL1 |
microglial cell activation involved in immune response | biological_process | TLR3 |
microglial cell proliferation | biological_process | CLU |
microtubule bundle formation | biological_process | MAP2, PLK1 |
microtubule cytoskeleton organization | biological_process | MAP2, AURKA, PTK2 |
microtubule depolymerization | biological_process | STMN1, SGK1 |
microtubule polymerization or depolymerization | biological_process | CRYAB |
microtubule-based movement | biological_process | NGF, KIFAP3 |
microtubule-based process | biological_process | KIFAP3 |
midbrain development | biological_process | FGFR1, WNT5A, FGFR2, CTNNB1, CMA1, WNT1 |
midbrain dopaminergic neuron differentiation | biological_process | WNT2 |
midbrain morphogenesis | biological_process | DKK1 |
midbrain-hindbrain boundary development | biological_process | WNT1 |
midbrain-hindbrain boundary maturation during brain development | biological_process | WNT1 |
middle ear morphogenesis | biological_process | FGFR1, EDN1, NAGLU |
midgut development | biological_process | WNT5A, CTNNB1 |
milk ejection reflex | biological_process | GJA1 |
mineralocorticoid biosynthetic process | biological_process | HSD3B2 |
mineralocorticoid receptor signaling pathway | biological_process | GPER1 |
miRNA loading onto RISC involved in gene silencing by miRNA | biological_process | DICER1 |
miRNA mediated inhibition of translation | biological_process | STAT3 |
mismatch repair | biological_process | MSH2, MSH6, MLH1, PCNA, PMS2 |
mitochondrial ATP synthesis coupled proton transport | biological_process | ATP5A1, ATP5B, STOML2 |
mitochondrial calcium ion transport | biological_process | STOML2 |
mitochondrial depolarization | biological_process | CASP1, CDKN2A |
mitochondrial electron transport, cytochrome c to oxygen | biological_process | MT-CO2 |
mitochondrial electron transport, NADH to ubiquinone | biological_process | NDUFS1 |
mitochondrial fragmentation involved in apoptotic process | biological_process | BAX |
mitochondrial fusion | biological_process | BAX |
mitochondrial genome maintenance | biological_process | TYMP |
mitochondrial protein processing | biological_process | STOML2 |
mitochondrial respiratory chain complex I assembly | biological_process | NDUFS1 |
mitochondrial transport | biological_process | HSP90AA1 |
mitochondrion morphogenesis | biological_process | BCL2L1, BAX |
mitochondrion organization | biological_process | NOS3, ATP5B, TERT, PARK7, STOML2, ATP7A, PPRC1 |
mitophagy | biological_process | GABARAPL1, CDKN2A |
mitophagy in response to mitochondrial depolarization | biological_process | ANXA5, PIK3CA, MSTN, C5, SFRP4 |
mitotic cell cycle | biological_process | CCNB1, AURKA, PAK4, DNMT3A, PAK1 |
mitotic cell cycle arrest | biological_process | CDKN1B, CDKN1A |
mitotic cell cycle checkpoint | biological_process | TGFB1, RB1, BCL2L1 |
mitotic centrosome separation | biological_process | AURKA |
mitotic cleavage furrow formation | biological_process | RHOA |
mitotic cytokinesis | biological_process | STMN1, PLK1 |
mitotic G1 DNA damage checkpoint | biological_process | CCND1, TP53, TP63 |
mitotic G2 DNA damage checkpoint | biological_process | HMGA2 |
mitotic metaphase plate congression | biological_process | CCNB1 |
mitotic nuclear division | biological_process | HMGA2, CCNB1, HGF, CHEK2, AURKA, BIRC5, LATS1, NR3C1, PLK1, FSD1 |
mitotic nuclear envelope disassembly | biological_process | CCNB1, PRKCB, PLK1 |
mitotic recombination-dependent replication fork processing | biological_process | BRCA2 |
mitotic sister chromatid segregation | biological_process | PLK1 |
mitotic spindle assembly | biological_process | CHEK2, BIRC5, RHOA |
mitotic spindle assembly checkpoint | biological_process | PLK1, ATM |
mitotic spindle organization | biological_process | CCNB1, STMN1, AURKA |
mitotic telomere maintenance via semi-conservative replication | biological_process | PCNA |
mitral valve formation | biological_process | NOTCH1 |
mitral valve morphogenesis | biological_process | EFNA1, TWIST1 |
modulation of synaptic transmission | biological_process | DRD2 |
monoamine transport | biological_process | SLC6A4, SLC6A2 |
monocarboxylic acid metabolic process | biological_process | CYP1A2 |
monocarboxylic acid transport | biological_process | BSG |
monocyte activation | biological_process | CSF1, FOXP1 |
monocyte aggregation | biological_process | CD44, IL1B |
monocyte chemotaxis | biological_process | CCL5, LGALS3, CCL3, IL6R, FLT1, CCL2, ANXA1, CCL25, CCL21, CCL22, CCL16, IL6, CCL19, CCL7, CX3CL1, CCL17, CCL11 |
monocyte differentiation | biological_process | VEGFA, BMP4, PPARG, JUN, CSF1R |
mononuclear cell migration | biological_process | LGALS3 |
mononuclear cell proliferation | biological_process | ACE, TGFB1 |
monosaccharide metabolic process | biological_process | AKR1B1 |
monoterpenoid metabolic process | biological_process | CYP2C19, CYP2E1, CYP1A2 |
monovalent inorganic cation transport | biological_process | ATP1B4 |
morphogenesis of a branching structure | biological_process | TDGF1, TGFB1, PRDM1, NOTCH4 |
morphogenesis of a polarized epithelium | biological_process | LAMA5, TP63 |
morphogenesis of an epithelial fold | biological_process | EGFR |
morphogenesis of an epithelial sheet | biological_process | HOXB2, JAG1 |
morphogenesis of an epithelium | biological_process | WNT5A, CA2 |
morphogenesis of embryonic epithelium | biological_process | FGFR2, CTNNB1, VEGFC, TGFB1I1, LAMA5 |
motogenic signaling involved in postnatal olfactory bulb interneuron migration | biological_process | FGFR1 |
motor learning | biological_process | DKK1 |
motor neuron apoptotic process | biological_process | FAS |
motor neuron axon guidance | biological_process | ERBB2, NRP1, SEMA3A |
movement of cell or subcellular component | biological_process | TXN, STAT3, VIM, CXCL8, FPR1, CXCR3, IL13, PTGS2, IGF1, IFNG, HSPB1, TPM3, PAK4, RAC1, PLAUR, ACTB, MST1R, IGSF8, NPY, CALD1 |
mRNA processing | biological_process | LGALS3, C1QBP, YBX1 |
mRNA splicing, via spliceosome | biological_process | YBX1, ELAVL1 |
mRNA stabilization | biological_process | MTOR, ELAVL1 |
mRNA transcription | biological_process | HSF1 |
mRNA transcription from RNA polymerase II promoter | biological_process | ARNT, HIF1A, POU5F1 |
mucus secretion | biological_process | AGR2 |
Mullerian duct regression | biological_process | AMH, AMHR2 |
multicellular organism aging | biological_process | EDN1, NR5A1, TP63 |
multicellular organism development | biological_process | GSK3B, FGF2, VEGFA, BMP4, CDX1, WNT5A, HMGA2, AKT1, SERPINF1, WNT2, NOTCH1, KDR, ID1, VDR, TNFRSF1B, CD40, PDGFRA, FLT1, CNTF, PAEP, CFC1B, LEPR, VCAN, HOXB2, LIF, STMN1, HOXA10, TYMP, MDK, BMP6, MMP11, HOXA11, L1CAM, SOX2, VEGFC, EGFR, FGF1, ANG, TP53, TNF, PDGFA, FYN, MEIS1, WNT7A, SNAI1, NRP1, ANGPT2, SPRY2, FIGF, NRP2, DKK1, IGF2, PRM1, WNT1, CSF1R, PTK2, NTRK2, HES5, DPYSL2, HEY1, MCL1, POU5F1, ELAVL1, SIRT1, ID2, TWIST1, CADM1, TP63, EMX2, NAA15, SLC26A8, JAG1, PAX2, DLX5, WNT4, DLL4, ANGPT1, SEMA3A, IHH, SFRP4, TBPL2, NOTCH4, CCL17, NODAL, OLFM1, SEMA3C, NANOG, TBX21, CHST2, TET3, CREB3L1, SMPD3 |
multicellular organism growth | biological_process | FGFR2, BRCA2, MTOR, CDC42 |
multicellular organismal iron ion homeostasis | biological_process | BMP6, HAMP |
multicellular organismal macromolecule metabolic process | biological_process | AKR1C3 |
multicellular organismal reproductive process | biological_process | COMT |
multicellular organismal response to stress | biological_process | LGALS1, IDO1, PTEN |
muscle cell cellular homeostasis | biological_process | SOD1, MSTN, IL6, HIF1A |
muscle contraction | biological_process | GJA1, ITGB5, TACR2, OXTR, CRYAB, TPM3, TMOD3, CALD1 |
muscle fiber development | biological_process | UCHL1 |
muscle filament sliding | biological_process | VIM, TPM3 |
muscle hypertrophy | biological_process | IGF1 |
muscle organ development | biological_process | IGF1, CRYAB, CXCL10, MSTN, LAMA5, NRG1, SIRT1, TWIST1, TAGLN |
muscle organ morphogenesis | biological_process | CNTF, LIF |
MyD88-dependent toll-like receptor signaling pathway | biological_process | HSPD1, CD36, MAP3K7, TLR2, TLR4, TLR9 |
MyD88-independent toll-like receptor signaling pathway | biological_process | TLR4, TLR3 |
myelin maintenance | biological_process | CXCR4 |
myelination | biological_process | TGFB1, ERBB2, TNFRSF21, NRG1 |
myelination in peripheral nervous system | biological_process | ADAM22 |
myeloid cell differentiation | biological_process | BCL6, TET2 |
myeloid cell homeostasis | biological_process | SOD1, BCL2L11, IL6, BAX, FOXP3 |
myeloid dendritic cell activation | biological_process | HMGB1 |
myeloid dendritic cell chemotaxis | biological_process | CCL19, CCR7 |
myeloid dendritic cell differentiation | biological_process | TGFB1, CSF2, IL4 |
myeloid leukocyte differentiation | biological_process | KIT |
myeloid progenitor cell differentiation | biological_process | KIT, BRAF, FLT3, TET2 |
myoblast development | biological_process | SDC1, SOX15 |
myoblast differentiation | biological_process | CTNNB1, LGALS1, IGF1, RB1, JAG1 |
myoblast fusion | biological_process | GSK3B, WNT1 |
myoblast migration involved in skeletal muscle regeneration | biological_process | ANXA1 |
myoblast proliferation | biological_process | HGF, IGF1, GPX1 |
myofibril assembly | biological_process | TMOD3 |
myotube cell development | biological_process | IGF1 |
myotube differentiation | biological_process | GSK3B, GPX1, WNT1 |
N-acetylglucosamine metabolic process | biological_process | CHST6, CHST2 |
N-terminal peptidyl-lysine acetylation | biological_process | KAT2B |
N-terminal peptidyl-methionine acetylation | biological_process | NAA15 |
N-terminal protein amino acid acetylation | biological_process | NAA15 |
NAD biosynthesis via nicotinamide riboside salvage pathway | biological_process | PNP |
nail development | biological_process | ITGA6 |
naphthalene metabolic process | biological_process | AKR1B1 |
natural killer cell activation | biological_process | IL12B, IL2RB, NCR1, ITGB2, IL18, IL2, ULBP2, KLRK1, KIR3DS1 |
natural killer cell activation involved in immune response | biological_process | IL12B |
natural killer cell differentiation | biological_process | AXL, IL15, TYRO3, ID2 |
natural killer cell inhibitory signaling pathway | biological_process | KIR2DL1 |
natural killer cell mediated cytotoxicity | biological_process | KIR3DL1, MICA, MICB, ULBP2 |
natural killer cell mediated immunity | biological_process | KLRD1 |
natural killer cell tolerance induction | biological_process | LGALS9 |
necroptotic process | biological_process | FASLG, TLR4, TLR3 |
necroptotic signaling pathway | biological_process | FASLG, FAS, TNF, TLR3 |
negative chemotaxis | biological_process | WNT5A, ITGB3, ITGAV, APOA1, PDGFA, SEMA3A, SEMA3C, RHOA |
negative regulation by host of viral exo-alpha-sialidase activity | biological_process | PTX3, APCS |
negative regulation by host of viral glycoprotein metabolic process | biological_process | PTX3, APCS |
negative regulation by host of viral process | biological_process | LTF |
negative regulation by host of viral transcription | biological_process | HMGA2, CCL5, CCL3, JUN, HDAC1 |
negative regulation of activated T cell proliferation | biological_process | CASP3, LGALS9, FOXP3 |
negative regulation of activin receptor signaling pathway | biological_process | FST, FSTL3 |
negative regulation of acute inflammatory response | biological_process | PPARG, GSTP1, APCS, IL4 |
negative regulation of adaptive immune response | biological_process | ALOX15 |
negative regulation of adenosine receptor signaling pathway | biological_process | ADA |
negative regulation of adenylate cyclase activity | biological_process | OPRM1, DRD2, CCR2 |
negative regulation of adiponectin secretion | biological_process | IL1B |
negative regulation of alkaline phosphatase activity | biological_process | TNF, TGFB2 |
negative regulation of alpha-beta T cell activation | biological_process | LILRB1 |
negative regulation of alpha-beta T cell differentiation | biological_process | IHH |
negative regulation of androgen receptor signaling pathway | biological_process | FOXP1, HDAC1, SIRT1, NODAL |
negative regulation of angiogenesis | biological_process | SERPINF1, FASLG, CXCR3, COL4A2, SPARC, CCL2, LIF, PTN, CCR2, CXCL10, ANGPT2, THBS1, KLK3, TEK, GHRL, IL17F, DCN |
negative regulation of anoikis | biological_process | BCL2, SRC, NOTCH1, PIK3CA, ITGB1, PTK2, BCL2L1, NTRK2, MCL1 |
negative regulation of anti-Mullerian hormone signaling pathway | biological_process | AMHR2 |
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological_process | THBS1 |
negative regulation of apoptotic cell clearance | biological_process | HMGB1 |
negative regulation of apoptotic process | biological_process | GCLC, GSK3B, BCL2, HSPD1, SRC, VEGFA, BCL6, STAT3, BMP4, CD40LG, WNT5A, HMGA2, CLU, PIK3R1, IL10, LEP, MMP9, MIF, ANXA5, AKT1, EPCAM, CFL1, NFKB1, CDKN1B, KDR, ID1, CASP3, FLT4, CDKN1A, BRAF, CTNNA1, AXL, ANXA4, PRLR, IL6ST, EDNRA, HGF, GSTP1, CD44, KITLG, FAS, TDGF1, IL2RB, WT1, HNF1B, PTGFR, FN1, AURKA, IGF1, GREM1, EGFR, JUN, CRYAB, ANXA1, SOD1, IGF1R, NGF, TIMP1, LTF, TP53, MYC, HSPB1, BIRC5, SGK1, CYR61, WNT7A, SOCS3, SPRY2, THBS1, PSMD10, CLDN7, GPX1, ADA, CAT, CD74, IL4, SERPINB2, MPO, IL6, CSF1R, PTEN, PLK1, PTK2, HDAC2, SMAD3, RELA, BCL2L1, PARK7, HIF1A, FOXO1, GAS6, PLAUR, TEK, GHRL, AIF1, MCL1, HDAC1, KIFAP3, SIRT1, TWIST1, DAPK1, PIM2, TP63, GATA6, NAA15, PAX2, UCN, IL2, DAD1, ANGPT1, IHH, ATAD3A, OGG1 |
negative regulation of apoptotic process involved in metanephric collecting duct development | biological_process | PAX2 |
negative regulation of apoptotic process involved in metanephric nephron tubule development | biological_process | PAX2 |
negative regulation of apoptotic signaling pathway | biological_process | BCL2, CTNNB1, HSPB1, BAX, WNT4 |
negative regulation of appetite | biological_process | LEP, PPARA, UCN |
negative regulation of appetite by leptin-mediated signaling pathway | biological_process | LEP |
negative regulation of astrocyte differentiation | biological_process | HES5 |
negative regulation of ATPase activity | biological_process | LTF |
negative regulation of auditory receptor cell differentiation | biological_process | NOTCH1 |
negative regulation of autophagy | biological_process | BCL2, MET, LEP, AKT1, HGF, LEPR, MTOR, BCL2L1, PTPN22 |
negative regulation of axon extension | biological_process | CCR2, NRP1, SEMA3A |
negative regulation of axon extension involved in axon guidance | biological_process | WNT5A, NRP1, SEMA3A, SEMA3C |
negative regulation of axonogenesis | biological_process | PTEN, PTK2, RHOA |
negative regulation of B cell activation | biological_process | FAS |
negative regulation of B cell apoptotic process | biological_process | BCL6, FOXP1, IRS2, IL2 |
negative regulation of B cell differentiation | biological_process | INHBA, INHA, ID2 |
negative regulation of B cell proliferation | biological_process | IL10, CASP3, CTLA4, TNFRSF21, PRDM1, ATM, CDKN2A |
negative regulation of behavior | biological_process | ESR2 |
negative regulation of beta-amyloid formation | biological_process | CLU, APOE |
negative regulation of bicellular tight junction assembly | biological_process | TNF |
negative regulation of binding of sperm to zona pellucida | biological_process | OVGP1 |
negative regulation of biomineral tissue development | biological_process | AHSG, GAS6 |
negative regulation of biosynthetic process | biological_process | GSTP1 |
negative regulation of blood coagulation | biological_process | ANXA5, APOE, SERPINE1, EDN1 |
negative regulation of blood coagulation, common pathway | biological_process | FGA |
negative regulation of blood pressure | biological_process | NOS2, DRD2, NOS3, VEGFC, CRH, ADIPOQ, PPARA, UCN |
negative regulation of blood vessel endothelial cell migration | biological_process | FGF2, HMGB1, AGTR2, TGFB1, APOE, ANGPT2, THBS1, DLL4 |
negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological_process | DLL4 |
negative regulation of BMP signaling pathway | biological_process | WNT5A, TOB1, NOTCH1, GREM1, FSTL3, SMAD7, DKK1, WNT1, HTRA1 |
negative regulation of bone mineralization | biological_process | CCL3, CCR1, GREM1, AHSG, HIF1A |
negative regulation of bone mineralization involved in bone maturation | biological_process | GREM1 |
negative regulation of bone remodeling | biological_process | GREM1 |
negative regulation of bone resorption | biological_process | TNFRSF11B |
negative regulation of bone trabecula formation | biological_process | GREM1 |
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway | biological_process | BMP4 |
negative regulation of branching involved in lung morphogenesis | biological_process | TNF |
negative regulation of branching involved in ureteric bud morphogenesis | biological_process | BMP4, GREM1 |
negative regulation of branching morphogenesis of a nerve | biological_process | IL1B |
negative regulation of calcidiol 1-monooxygenase activity | biological_process | NFKB1 |
negative regulation of calcium ion import | biological_process | SPINK1, CRHR2 |
negative regulation of calcium ion transmembrane transport | biological_process | PTGER3 |
negative regulation of calcium ion transport | biological_process | NOS3, PTGS2, ICAM1, STC1, LILRB1 |
negative regulation of calcium ion transport into cytosol | biological_process | BCL2 |
negative regulation of calcium ion-dependent exocytosis | biological_process | NOTCH1 |
negative regulation of calcium-transporting ATPase activity | biological_process | TLR9 |
negative regulation of cAMP biosynthetic process | biological_process | OPRM1, EDNRA, PTGER3, EDN1, CRHR2 |
negative regulation of cAMP-dependent protein kinase activity | biological_process | SIRT1 |
negative regulation of cAMP-mediated signaling | biological_process | OPRM1 |
negative regulation of canonical Wnt signaling pathway | biological_process | GSK3B, EGR1, WNT5A, IGFBP2, NOTCH1, IGFBP1, IGFBP4, SOX2, PSMD9, GREM1, APOE, LATS1, DKK1, PSMD10, FOXO1, HDAC1, WNT4, SFRP4 |
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | biological_process | DKK1 |
negative regulation of cardiac muscle cell apoptotic process | biological_process | NRG1 |
negative regulation of cardiac muscle cell differentiation | biological_process | DKK1 |
negative regulation of cardiac muscle cell proliferation | biological_process | GJA1 |
negative regulation of cardiac muscle hypertrophy | biological_process | GSK3B |
negative regulation of cardiac muscle hypertrophy in response to stress | biological_process | ERRFI1 |
negative regulation of cartilage development | biological_process | LEP, TGFB2 |
negative regulation of catagen | biological_process | CDH3 |
negative regulation of catalytic activity | biological_process | ANXA5, NOTCH1, ANXA4, PTN, TIMP1, ANXA2, SET, ATP7A, TIMP4 |
negative regulation of cation channel activity | biological_process | MMP9 |
negative regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | HMGB1 |
negative regulation of CD4-positive, alpha-beta T cell proliferation | biological_process | LGALS9 |
negative regulation of CD8-positive, alpha-beta T cell activation | biological_process | LILRB1 |
negative regulation of cell adhesion | biological_process | FBLN1, PIK3R1, ERBB3, TNC, CLDN7, AGER, ADAM22, ANGPT1 |
negative regulation of cell adhesion involved in substrate-bound cell migration | biological_process | ATP5B |
negative regulation of cell adhesion mediated by integrin | biological_process | MUC1, SERPINE1, CYP1B1 |
negative regulation of cell adhesion molecule production | biological_process | APOA1 |
negative regulation of cell aging | biological_process | MIF, WNT1, PTEN |
negative regulation of cell cycle | biological_process | GATA3, INHBA, BMP4, HPGD, CASP3, PTGS2, TGFB1, INHA, RB1, RUNX3, PLA2G16, LILRB1 |
negative regulation of cell cycle arrest | biological_process | CCND1, MIF, CHEK2, GPER1 |
negative regulation of cell cycle process | biological_process | GPER1 |
negative regulation of cell death | biological_process | FGF2, STAT3, BMP4, CCL5, NOTCH1, NTF4, CYR61, CTSB, AGR2, CRH, PARK7, NFE2L2, ESR2, SMAD4, UCN |
negative regulation of cell development | biological_process | NODAL |
negative regulation of cell differentiation | biological_process | BCL6, MAPK1, CTNNB1, NOTCH1, ITGB1, TGFB1, KRAS, WNT1, TWIST1, JAG1, WNT4, NOTCH4, NODAL |
negative regulation of cell differentiation involved in embryonic placenta development | biological_process | SNAI1 |
negative regulation of cell division | biological_process | MYC |
negative regulation of cell growth | biological_process | BCL2, INHBA, BCL6, PPARG, GJA1, CDKN1B, CDKN1A, CDKN2A, AGTR2, WT1, GREM1, CRYAB, TGFB1, TP53, ENO1, GDF9, TGFB2, SMAD3, ESR2, SIRT1, SMAD4, TRO, ADIPOR2, ADIPOR1, RERG |
negative regulation of cell migration | biological_process | BCL2, DRD2, ENG, IGFBP5, PTN, CCR2, SMAD7, SERPINE1, PTEN, ADIPOQ, IL24, WNT4, CYP1B1, STC1 |
negative regulation of cell migration involved in sprouting angiogenesis | biological_process | NOTCH1, DLL4, RHOA |
negative regulation of cell motility | biological_process | GATA3, FBLN1, CTNNA1 |
negative regulation of cell projection organization | biological_process | ITGA3, ITGB1, SPRY2 |
negative regulation of cell proliferation | biological_process | BCL2, GATA3, INHBA, BCL6, STAT3, BMP4, F2R, PPARG, GJA1, IGFBP3, CXCL8, OPRM1, CTNNB1, HMGA1, AR, TOB1, CDKN1B, NOTCH1, NME1, DRD2, CDKN1A, CDKN2A, VDR, CXCL1, HMOX1, AZGP1, LIF, TIMP2, WT1, NOS3, SSTR1, ADM, SSTR5, PTGS2, VEGFC, ZEB1, COL18A1, RARRES1, ITGB1, JUN, IFNG, TGFB1, IL1A, BCHE, TP53, PTGES, RB1, KLF11, TGFB1I1, SPRY2, IL1B, IL6, CSF1R, PTEN, TGFB2, SMAD3, BAX, HSF1, SMAD2, KAT2B, FOXP3, KIFAP3, SMAD4, RARRES3, GPER1, PIM2, IL1RL1, IL24, IGFBP7, KLF10, DLL4, SST, KISS1R, KISS1, CYP1B1, SFRP4, CHD5, RERG, PEMT |
negative regulation of cell proliferation in midbrain | biological_process | WNT5A |
negative regulation of cell proliferation involved in contact inhibition | biological_process | PAK1 |
negative regulation of cell proliferation involved in heart morphogenesis | biological_process | BMP4 |
negative regulation of cell proliferation involved in mesonephros development | biological_process | GATA3 |
negative regulation of cell size | biological_process | AKT1, MTOR, PTEN, UCN |
negative regulation of cell volume | biological_process | CLCN3 |
negative regulation of cell-cell adhesion | biological_process | CDH1, TGFB1, WNT1, PTK2 |
negative regulation of cell-cell adhesion mediated by cadherin | biological_process | EPCAM |
negative regulation of cell-matrix adhesion | biological_process | BCL6, PIK3R1, CDKN2A, THBS1, POSTN |
negative regulation of cell-substrate adhesion | biological_process | NOTCH1, LGALS1, ANGPT2, WNT1 |
negative regulation of cellular component movement | biological_process | CDKN1B, ACTN4 |
negative regulation of cellular pH reduction | biological_process | BCL2 |
negative regulation of cellular protein metabolic process | biological_process | MIF, NFKB1, EDN1 |
negative regulation of cellular response to testosterone stimulus | biological_process | SIRT1 |
negative regulation of cellular senescence | biological_process | BCL6, TERT, SIRT1, TWIST1, TP63 |
negative regulation of centriole replication | biological_process | BRCA1 |
negative regulation of cerebellar granule cell precursor proliferation | biological_process | SLC6A4 |
negative regulation of cGMP-mediated signaling | biological_process | THBS1 |
negative regulation of chemokine (C-C motif) ligand 5 production | biological_process | IL10 |
negative regulation of chemokine biosynthetic process | biological_process | IL6 |
negative regulation of chemokine production | biological_process | LGALS9 |
negative regulation of chemokine secretion | biological_process | F2RL1 |
negative regulation of chemokine-mediated signaling pathway | biological_process | CCL5 |
negative regulation of cholangiocyte apoptotic process | biological_process | MTOR, IGF1 |
negative regulation of cholesterol biosynthetic process | biological_process | SOD1, APOE |
negative regulation of cholesterol efflux | biological_process | APOE, EGF |
negative regulation of cholesterol import | biological_process | APOA2 |
negative regulation of cholesterol storage | biological_process | PPARG, PPARA |
negative regulation of cholesterol transport | biological_process | NFKB1, APOA2 |
negative regulation of cholesterol transporter activity | biological_process | APOA2 |
negative regulation of chondrocyte differentiation | biological_process | BMP4, CTNNB1, GREM1 |
negative regulation of chondrocyte proliferation | biological_process | BMPR1B |
negative regulation of chorionic trophoblast cell proliferation | biological_process | NODAL |
negative regulation of chromatin silencing | biological_process | HMGA1 |
negative regulation of chronic inflammatory response | biological_process | CYP19A1, IL4, FOXP3 |
negative regulation of chronic inflammatory response to antigenic stimulus | biological_process | IL10 |
negative regulation of circadian rhythm | biological_process | SUV39H1, SUV39H2 |
negative regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | ADA |
negative regulation of circadian sleep/wake cycle, REM sleep | biological_process | PTGER4, CRH, GHRL |
negative regulation of circadian sleep/wake cycle, sleep | biological_process | DRD2 |
negative regulation of circadian sleep/wake cycle, wakefulness | biological_process | PTGER3 |
negative regulation of coagulation | biological_process | ANXA5 |
negative regulation of collagen biosynthetic process | biological_process | PPARG, IL6R, IL6, ERRFI1, AGER |
negative regulation of collateral sprouting of intact axon in response to injury | biological_process | SPP1 |
negative regulation of complement activation, classical pathway | biological_process | C4BPA |
negative regulation of complement activation, lectin pathway | biological_process | A2M |
negative regulation of complement-dependent cytotoxicity | biological_process | IL13, IL4 |
negative regulation of corticotropin secretion | biological_process | CRHBP |
negative regulation of corticotropin-releasing hormone receptor activity | biological_process | CRHBP |
negative regulation of CREB transcription factor activity | biological_process | FOXP3 |
negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological_process | NR2F2, CDKN1B, CASP3, CDKN1A, CDKN2A, LATS1, PLK1, KAT2B |
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological_process | PTEN |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | SRC, VEGFA, AKT1, HGF, CD44, CRYAB, NGF, BIRC5, THBS1, GPX1, IL6, GAS6, PAX2 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological_process | MMP9, PARK7, PLAUR |
negative regulation of cytokine activity | biological_process | IL10 |
negative regulation of cytokine biosynthetic process | biological_process | TIA1, FOXP3 |
negative regulation of cytokine production | biological_process | IL10, NFKB1 |
negative regulation of cytokine secretion | biological_process | PTGER4, IL6, FOXP3, CX3CL1 |
negative regulation of cytokine secretion involved in immune response | biological_process | IL10, APOA1, APOA2, TNF, ANGPT1, LILRB1 |
negative regulation of cytokine-mediated signaling pathway | biological_process | IL1RN |
negative regulation of cytolysis | biological_process | CSF2, PAX2 |
negative regulation of cytosolic calcium ion concentration | biological_process | OPRM1, DRD2 |
negative regulation of death-inducing signaling complex assembly | biological_process | PARK7 |
negative regulation of defecation | biological_process | CRHR2 |
negative regulation of defense response to virus | biological_process | IL2RA, C1QBP, HTRA1 |
negative regulation of defense response to virus by host | biological_process | MICB |
negative regulation of dendrite development | biological_process | GSK3B |
negative regulation of dendrite morphogenesis | biological_process | GSK3B, ID1, YWHAH |
negative regulation of dendritic cell antigen processing and presentation | biological_process | THBS1 |
negative regulation of dendritic cell apoptotic process | biological_process | AXL, GAS6, LILRB1 |
negative regulation of dendritic cell dendrite assembly | biological_process | CCL21 |
negative regulation of dendritic cell differentiation | biological_process | HLA-G, LILRB1 |
negative regulation of dendritic spine development | biological_process | APOE, HDAC2 |
negative regulation of dendritic spine maintenance | biological_process | APOE |
negative regulation of dendritic spine morphogenesis | biological_process | EFNA1, PTEN |
negative regulation of DNA binding | biological_process | HMGA2, ID1, HMOX1, JUN, HDAC2, ID2 |
negative regulation of DNA biosynthetic process | biological_process | GJA1, ADIPOQ |
negative regulation of DNA damage checkpoint | biological_process | CHEK2 |
negative regulation of DNA damage response, signal transduction by p53 class mediator | biological_process | MIF, CD44, SNAI1, PSMD10, CD74, SIRT1, TWIST1 |
negative regulation of DNA demethylation | biological_process | GATA3 |
negative regulation of DNA metabolic process | biological_process | GPER1 |
negative regulation of DNA recombination | biological_process | MSH2, MSH6 |
negative regulation of DNA replication | biological_process | TGFB1 |
negative regulation of dopamine metabolic process | biological_process | COMT |
negative regulation of dopamine receptor signaling pathway | biological_process | DRD2 |
negative regulation of dopamine secretion | biological_process | DRD2 |
negative regulation of dopaminergic neuron differentiation | biological_process | GSK3B |
negative regulation of double-strand break repair | biological_process | TWIST1 |
negative regulation of double-strand break repair via nonhomologous end joining | biological_process | HMGA2 |
negative regulation of double-strand break repair via single-strand annealing | biological_process | OGG1 |
negative regulation of ductus arteriosus closure | biological_process | PTGER4 |
negative regulation of endocytosis | biological_process | LGALS3, LILRB1 |
negative regulation of endodermal cell differentiation | biological_process | COL5A2 |
negative regulation of endopeptidase activity | biological_process | AKT1, SERPINF1, C4A, TIMP2, SERPINA6, A2M, SERPINA1, AHSG, TIMP1, C3, SLPI, SERPINE1, C5, SERPINB2, WFDC2, TIMP4 |
negative regulation of endoplasmic reticulum calcium ion concentration | biological_process | BAX |
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological_process | PARK7, CREB3L1 |
negative regulation of endothelial cell apoptotic process | biological_process | GATA3, IL10, KDR, BRAF, IL11, IL13, FGA, SERPINE1, ICAM1, IL4, GAS6, TEK, NFE2L2, ANGPT1 |
negative regulation of endothelial cell chemotaxis | biological_process | NOTCH1, THBS1 |
negative regulation of endothelial cell chemotaxis to fibroblast growth factor | biological_process | CXCL13 |
negative regulation of endothelial cell differentiation | biological_process | XDH, ID1, NOTCH4 |
negative regulation of endothelial cell migration | biological_process | NR2F2, SERPINF1, THBS1, AGER, DLL4, DCN, STC1 |
negative regulation of endothelial cell proliferation | biological_process | XDH, ATP5A1, NR2F2, GJA1, CXCR3, ENG, SPARC, APOE, THBS1, GHRL, AGER |
negative regulation of endothelin secretion | biological_process | PTGER4 |
negative regulation of energy homeostasis | biological_process | GHRL |
negative regulation of entry of bacterium into host cell | biological_process | ITGAV |
negative regulation of eosinophil degranulation | biological_process | CCR2 |
negative regulation of eosinophil extravasation | biological_process | PTGER4 |
negative regulation of epidermal cell differentiation | biological_process | EZH2 |
negative regulation of epidermal growth factor receptor signaling pathway | biological_process | EGFR, SPRY2, EGF, CDC42, ERRFI1 |
negative regulation of epidermal growth factor-activated receptor activity | biological_process | ERRFI1 |
negative regulation of epinephrine secretion | biological_process | PTGS1, CRH, CRHR2 |
negative regulation of epithelial cell differentiation | biological_process | YAP1, CCND1, ZEB1, IFNG |
negative regulation of epithelial cell migration | biological_process | IL4, PTPRR, SEMA3A |
negative regulation of epithelial cell proliferation | biological_process | BMP4, WNT5A, FGFR2, ATF2, CDKN1B, PTN, SOX2, TGFB1, RB1, PTEN, RUNX3, TGFB2, ESR2 |
negative regulation of epithelial cell proliferation involved in prostate gland development | biological_process | SERPINF1, CDKN1B |
negative regulation of epithelial to mesenchymal transition | biological_process | EFNA1, SMAD7 |
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | TGFB2 |
negative regulation of ERK1 and ERK2 cascade | biological_process | FBLN1, GSTP1, LIF, TIMP3, TLR4, SPRY2, PTEN, ADIPOQ, ERRFI1, GPER1, PTPRR |
negative regulation of establishment of protein localization to plasma membrane | biological_process | BCL2L1 |
negative regulation of excitatory postsynaptic potential | biological_process | PTEN |
negative regulation of execution phase of apoptosis | biological_process | CXCR3, BCL2L1 |
negative regulation of exo-alpha-sialidase activity | biological_process | PTX3, APCS |
negative regulation of exocytosis | biological_process | ANXA1 |
negative regulation of extracellular matrix disassembly | biological_process | TGFB1 |
negative regulation of extrinsic apoptotic signaling pathway | biological_process | GCLC, SRC, ITGA6, YAP1, LGALS3, AR, GSTP1, IGF1, ITGAV, NRP1, THBS1, IL4, RELA, PARK7 |
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological_process | BCL2, AKT1, CTNNA1, IL1A, TNF, TERT, FYN, IL1B, CSF2, NRG1, BCL2L1, MCL1, CX3CL1 |
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological_process | BRCA1, TNFSF10, FASLG, HGF, HMOX1, FAS, NOS3, FGA, SERPINE1, GPX1, ICAM1, DAPK1 |
negative regulation of fat cell differentiation | biological_process | GATA3, WNT5A, GATA2, MMP11, TGFB1, TNF, TGFB1I1, WNT1, IL6, SMAD3, FOXO1, ADIPOQ, SIRT1, GPER1, JAG1 |
negative regulation of fat cell proliferation | biological_process | GATA2 |
negative regulation of fatty acid beta-oxidation | biological_process | AKT1 |
negative regulation of fatty acid biosynthetic process | biological_process | BRCA1 |
negative regulation of feeding behavior | biological_process | ESR2, UCN, CRHR2, RETN |
negative regulation of female gonad development | biological_process | WT1, NR5A1 |
negative regulation of ferrous iron export | biological_process | HAMP |
negative regulation of fibrinolysis | biological_process | USF1, SERPINE1, THBS1, CPB2 |
negative regulation of fibroblast apoptotic process | biological_process | PIK3CA, GAS6 |
negative regulation of fibroblast growth factor receptor signaling pathway | biological_process | WNT5A, SPRY2, THBS1, WNT4 |
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | biological_process | GATA3 |
negative regulation of fibroblast migration | biological_process | FGF2, BRAF |
negative regulation of fibroblast proliferation | biological_process | AGTR2, GSTP1, TP53, MYC, LTA, BAX |
negative regulation of focal adhesion assembly | biological_process | SRC, MMP14, THBS1, PTEN |
negative regulation of follicle-stimulating hormone secretion | biological_process | INHBA, INHA, CRHR2, UCN2 |
negative regulation of forebrain neuron differentiation | biological_process | PTGER3, HES5 |
negative regulation of G-protein coupled receptor protein signaling pathway | biological_process | CCL5, CXCL8 |
negative regulation of G1/S transition of mitotic cell cycle | biological_process | BCL2, CDKN1A, RB1, PTEN, EZH2 |
negative regulation of gap junction assembly | biological_process | ACE |
negative regulation of gastric acid secretion | biological_process | OXTR, PTGER3, UCN |
negative regulation of gastrin-induced gastric acid secretion | biological_process | PTGER3 |
negative regulation of gene expression | biological_process | XDH, FGFR1, GATA3, NOS2, BMP4, GJA1, CD36, MIF, AKT1, CTNNB1, CCNB1, CCL3, SERPINF1, NME1, ID1, CCR1, CDKN1A, ESR1, INSR, IFNG, CRYAB, TGFB1, TNF, TERT, LGALS9, FYN, RB1, PRDM1, PGR, IL1B, CRH, CDC42, TGFB2, PARK7, SMAD2, AIF1, HDAC1, EZH2, SIRT1, ID2, PTPN22, GPER1, NR0B2, UCN, WNT4, DLL4, CRHR2, OLFM1, UCN2 |
negative regulation of gene expression, epigenetic | biological_process | DNMT1, DNMT3A, EZH2, DNMT3B, HIST2H3A |
negative regulation of gene silencing by miRNA | biological_process | TGFB1, POU5F1 |
negative regulation of glial cell apoptotic process | biological_process | CCL2 |
negative regulation of glial cell proliferation | biological_process | NOTCH1, PTN |
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation | biological_process | GATA3 |
negative regulation of glomerular filtration | biological_process | F2R |
negative regulation of glomerular mesangial cell proliferation | biological_process | BMP4 |
negative regulation of glomerulus development | biological_process | BMP4 |
negative regulation of glucagon secretion | biological_process | LEP, CRH |
negative regulation of glucocorticoid receptor signaling pathway | biological_process | CLOCK |
negative regulation of gluconeogenesis | biological_process | LEPR, IL6, ADIPOQ, MST1 |
negative regulation of glucose import | biological_process | LEP, ESR1, TNF |
negative regulation of glucose transport | biological_process | PRKCB, IL1B |
negative regulation of glutamate secretion | biological_process | IL1B |
negative regulation of glutamine transport | biological_process | LEP |
negative regulation of glycogen (starch) synthase activity | biological_process | GSK3B |
negative regulation of glycogen biosynthetic process | biological_process | GSK3B |
negative regulation of glycolytic process | biological_process | STAT3, PPARA |
negative regulation of glycoprotein metabolic process | biological_process | PTX3, APCS |
negative regulation of granulocyte differentiation | biological_process | ADIPOQ |
negative regulation of growth | biological_process | IGFBP5, HIF1A |
negative regulation of growth of symbiont in host | biological_process | CD36, IL10, IL12B, MBL2, IFNG, TNF, LTA, MPO, CTSG |
negative regulation of growth of symbiont involved in interaction with host | biological_process | IFNG |
negative regulation of GTPase activity | biological_process | SPRY2, KLRK1 |
negative regulation of heart contraction | biological_process | IL2 |
negative regulation of heart rate | biological_process | AGTR2 |
negative regulation of helicase activity | biological_process | TP53, SIRT1 |
negative regulation of hematopoietic stem cell differentiation | biological_process | NFE2L2 |
negative regulation of hepatocyte proliferation | biological_process | CPB2 |
negative regulation of heterotypic cell-cell adhesion | biological_process | IL1RN, APOA1, ADIPOQ |
negative regulation of histone acetylation | biological_process | BRCA1, SET, FOXP3, TWIST1 |
negative regulation of histone deacetylation | biological_process | FOXP3, UCN |
negative regulation of histone H3-K14 acetylation | biological_process | SIRT1 |
negative regulation of histone H3-K4 methylation | biological_process | BRCA1 |
negative regulation of histone H3-K9 methylation | biological_process | DNMT1, BRCA1, DNMT3B |
negative regulation of histone H4-K16 acetylation | biological_process | SIRT1 |
negative regulation of histone phosphorylation | biological_process | TWIST1 |
negative regulation of hormone secretion | biological_process | LIF, IL11, IL6, EDN1, ADIPOQ, UCN |
negative regulation of hyaluronan biosynthetic process | biological_process | TGFB1 |
negative regulation of hydrogen peroxide biosynthetic process | biological_process | STAT3 |
negative regulation of hydrogen peroxide catabolic process | biological_process | HP |
negative regulation of hydrogen peroxide metabolic process | biological_process | PTGER4, MMP3 |
negative regulation of hydrogen peroxide-induced cell death | biological_process | TXN, PSAP, PARK7, NFE2L2 |
negative regulation of hydrogen peroxide-induced neuron death | biological_process | PARK7 |
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway | biological_process | PARK7 |
negative regulation of hydrogen peroxide-mediated programmed cell death | biological_process | MET, HGF |
negative regulation of hydrolase activity | biological_process | LEPR, NOS3, APOA1 |
negative regulation of I-kappaB kinase/NF-kappaB signaling | biological_process | GSTP1, ESR1, CCDC22, ADIPOQ, SIRT1, IL1RL1 |
negative regulation of icosanoid secretion | biological_process | AGTR2 |
negative regulation of immature T cell proliferation in thymus | biological_process | BMP4, ERBB2, CDKN2A, IHH |
negative regulation of immune response | biological_process | HLA-G, TGFB1, IL2RA, TGFB2, FOXP3 |
negative regulation of immunoglobulin secretion | biological_process | IL33 |
negative regulation of immunological synapse formation | biological_process | LGALS3 |
negative regulation of inflammatory response | biological_process | GATA3, TNFRSF1A, IL10, PTGER4, SERPINF1, NFKB1, TNFRSF1B, HGF, SAA1, APOA1, APOE, SOCS3, ADA, KRT1, IL2RA, SMAD3, TYRO3, TEK, ADIPOQ, GHRL, PPARA, FOXP3, GPER1, IL2 |
negative regulation of inflammatory response to antigenic stimulus | biological_process | IL12B, GPX1 |
negative regulation of innate immune response | biological_process | DRD2, TYRO3 |
negative regulation of inner ear receptor cell differentiation | biological_process | HES5 |
negative regulation of insulin receptor signaling pathway | biological_process | PRKCB, AHSG, SOCS3, MSTN, IL1B, RELA |
negative regulation of insulin secretion | biological_process | DRD2, PTGER3, PSMD9, GHRL |
negative regulation of insulin secretion involved in cellular response to glucose stimulus | biological_process | CRHR2 |
negative regulation of insulin-like growth factor receptor signaling pathway | biological_process | IGFBP5 |
negative regulation of integrin activation | biological_process | PTGER4 |
negative regulation of integrin biosynthetic process | biological_process | AR |
negative regulation of integrin-mediated signaling pathway | biological_process | CTNNA1 |
negative regulation of interferon-alpha biosynthetic process | biological_process | IL10 |
negative regulation of interferon-beta secretion | biological_process | LILRB1 |
negative regulation of interferon-gamma biosynthetic process | biological_process | INHBA, INHA, FOXP3, LILRB1 |
negative regulation of interferon-gamma production | biological_process | GATA3, HMGB1, IL10, AXL, HLA-DRB1, LGALS9, TLR4, IL33, C1QBP, GAS6, FOXP3, IL1RL1, IL20RB, LILRB1 |
negative regulation of interferon-gamma-mediated signaling pathway | biological_process | PPARG |
negative regulation of interleukin-1 alpha secretion | biological_process | PTGER4 |
negative regulation of interleukin-1 beta production | biological_process | GSTP1, GHRL, ERRFI1 |
negative regulation of interleukin-1 beta secretion | biological_process | APOA1 |
negative regulation of interleukin-1 production | biological_process | IL10 |
negative regulation of interleukin-1 secretion | biological_process | GAS6 |
negative regulation of interleukin-1-mediated signaling pathway | biological_process | IL1RN |
negative regulation of interleukin-10 production | biological_process | IL12B, IDO1, FOXP3, AGER, IL23A |
negative regulation of interleukin-10 secretion | biological_process | TNFRSF21, LILRB1 |
negative regulation of interleukin-12 biosynthetic process | biological_process | NFKB1 |
negative regulation of interleukin-12 production | biological_process | IL10, THBS1, C1QBP |
negative regulation of interleukin-12 secretion | biological_process | LILRB1 |
negative regulation of interleukin-13 secretion | biological_process | TNFRSF21 |
negative regulation of interleukin-17 production | biological_process | IL12B, IL12A, IFNG, TGFB1, TLR4, FOXP3 |
negative regulation of interleukin-18 production | biological_process | IL10 |
negative regulation of interleukin-2 biosynthetic process | biological_process | FOXP3 |
negative regulation of interleukin-2 production | biological_process | GATA3, FOXP3, IL20RB |
negative regulation of interleukin-23 production | biological_process | TLR4, RAC1 |
negative regulation of interleukin-4 production | biological_process | FOXP3, CD83 |
negative regulation of interleukin-5 production | biological_process | FOXP3 |
negative regulation of interleukin-5 secretion | biological_process | TNFRSF21 |
negative regulation of interleukin-6 biosynthetic process | biological_process | GHRL |
negative regulation of interleukin-6 production | biological_process | IL10, HGF, TNF, TLR4, GAS6, TLR9, FOXP3 |
negative regulation of interleukin-6 secretion | biological_process | GAS6, PTPN22 |
negative regulation of interleukin-6-mediated signaling pathway | biological_process | IL6ST |
negative regulation of interleukin-8 production | biological_process | IL10, IL6R, TLR9 |
negative regulation of interleukin-8 secretion | biological_process | ANXA4, ANXA1, PTPN22 |
negative regulation of intestinal absorption | biological_process | HAMP |
negative regulation of intracellular estrogen receptor signaling pathway | biological_process | BRCA1, ZNF366 |
negative regulation of intracellular protein transport | biological_process | ADIPOQ |
negative regulation of intracellular transport | biological_process | CRYAB |
negative regulation of intrinsic apoptotic signaling pathway | biological_process | BCL2, SRC, MMP9, BCL2L1, PLAUR, MCL1 |
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | biological_process | CLU, CXCL12, SNAI1, BCL2L1 |
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological_process | MIF, MUC1, CD44, CD74, SIRT1 |
negative regulation of iodide transmembrane transport | biological_process | MTOR |
negative regulation of ion transmembrane transporter activity | biological_process | HAMP |
negative regulation of iron channel activity | biological_process | HAMP |
negative regulation of isotype switching to IgE isotypes | biological_process | BCL6, FOXP3 |
negative regulation of JAK-STAT cascade | biological_process | BGN, SOCS3, DCN |
negative regulation of JNK cascade | biological_process | AKT1, F2RL1 |
negative regulation of JUN kinase activity | biological_process | GSTP1, PTPN22 |
negative regulation of keratinocyte differentiation | biological_process | TP63 |
negative regulation of keratinocyte proliferation | biological_process | VDR, KLF9 |
negative regulation of kinase activity | biological_process | CDKN1B, MSTN, IRS2 |
negative regulation of leukocyte activation | biological_process | GPER1 |
negative regulation of leukocyte apoptotic process | biological_process | CXCL12, CCL21, CCL19, CCR7 |
negative regulation of leukocyte cell-cell adhesion | biological_process | PPARA |
negative regulation of leukocyte chemotaxis | biological_process | GREM1 |
negative regulation of leukocyte migration | biological_process | HMOX1, IL33, ADA |
negative regulation of leukocyte proliferation | biological_process | GSTP1 |
negative regulation of leukocyte tethering or rolling | biological_process | CXCL12, CCL25, CCL21 |
negative regulation of lipase activity | biological_process | APOA1, APOA2 |
negative regulation of lipid biosynthetic process | biological_process | APOE, GPER1 |
negative regulation of lipid catabolic process | biological_process | APOA2, TNF, IL1B |
negative regulation of lipid metabolic process | biological_process | IL1B |
negative regulation of lipid storage | biological_process | LEP, ITGB3, ITGAV, TNF, CRP, IL6 |
negative regulation of lipid transport | biological_process | ITGB3, ITGAV |
negative regulation of lipid transport across blood brain barrier | biological_process | APOE |
negative regulation of lipopolysaccharide-mediated signaling pathway | biological_process | LTF, PRDM1 |
negative regulation of lipoprotein metabolic process | biological_process | ITGB3, ITGAV |
negative regulation of locomotion | biological_process | GHRL |
negative regulation of low-density lipoprotein particle receptor biosynthetic process | biological_process | ITGB3, ITGAV, ADIPOQ |
negative regulation of low-density lipoprotein particle receptor catabolic process | biological_process | ANXA2 |
negative regulation of lung ciliated cell differentiation | biological_process | IL13 |
negative regulation of luteinizing hormone secretion | biological_process | TACR2, CRH, CRHR2, UCN2 |
negative regulation of lymphocyte activation | biological_process | AXL, TYRO3 |
negative regulation of lymphocyte proliferation | biological_process | IL2RA, FOXP3, IL2 |
negative regulation of macroautophagy | biological_process | MTOR |
negative regulation of macrophage activation | biological_process | IL4 |
negative regulation of macrophage apoptotic process | biological_process | CCL5, NOD2 |
negative regulation of macrophage chemotaxis | biological_process | CYP19A1, C5 |
negative regulation of macrophage cytokine production | biological_process | TGFB1, TGFB2 |
negative regulation of macrophage derived foam cell differentiation | biological_process | CETP, PPARG, ITGB3, ITGAV, CRP, ADIPOQ, PPARA |
negative regulation of macrophage differentiation | biological_process | INHBA, GATA2, INHA, ADIPOQ |
negative regulation of male germ cell proliferation | biological_process | PTGDS |
negative regulation of male gonad development | biological_process | WNT4 |
negative regulation of mammary gland epithelial cell proliferation | biological_process | GATA3, BRCA2 |
negative regulation of MAP kinase activity | biological_process | GSK3B, BMP4, UCHL1, GSTP1, APOE, SPRY2, IL1B, ADIPOQ |
negative regulation of MAPK cascade | biological_process | GSTP1, PSMD10 |
negative regulation of mast cell apoptotic process | biological_process | KITLG, FCER1G |
negative regulation of mast cell cytokine production | biological_process | BCL6, HMOX1 |
negative regulation of mast cell degranulation | biological_process | HMOX1, LGALS9 |
negative regulation of mature B cell apoptotic process | biological_process | MIF, ADA, CD74 |
negative regulation of MDA-5 signaling pathway | biological_process | C1QBP |
negative regulation of meiotic nuclear division | biological_process | LIF |
negative regulation of melanin biosynthetic process | biological_process | WNT5A |
negative regulation of membrane potential | biological_process | PTN |
negative regulation of membrane protein ectodomain proteolysis | biological_process | IL10, TIMP2, TIMP3, TIMP1, TIMP4 |
negative regulation of mesenchymal cell apoptotic process | biological_process | HIF1A |
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis | biological_process | HNF1B |
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis | biological_process | PAX2 |
negative regulation of mesenchymal cell apoptotic process involved in metanephros development | biological_process | HNF1B, PAX2 |
negative regulation of mesenchymal cell proliferation | biological_process | WNT5A, PTN |
negative regulation of mesenchymal cell proliferation involved in ureter development | biological_process | BMP4 |
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological_process | CTNNB1 |
negative regulation of mesoderm development | biological_process | TP63 |
negative regulation of mesodermal cell fate specification | biological_process | DKK1 |
negative regulation of metabolic process | biological_process | LEP |
negative regulation of metalloendopeptidase activity | biological_process | TIMP3 |
negative regulation of metanephric comma-shaped body morphogenesis | biological_process | BMP4 |
negative regulation of metanephric glomerular mesangial cell proliferation | biological_process | WT1 |
negative regulation of metanephric mesenchymal cell migration | biological_process | ADIPOQ |
negative regulation of metanephric S-shaped body morphogenesis | biological_process | BMP4 |
negative regulation of methylation-dependent chromatin silencing | biological_process | TET1 |
negative regulation of MHC class II biosynthetic process | biological_process | IL10, HDAC2 |
negative regulation of microtubule polymerization | biological_process | STMN1, SGK1, FKBP4 |
negative regulation of microtubule polymerization or depolymerization | biological_process | FKBP4 |
negative regulation of mitochondrial depolarization | biological_process | BCL2, SRC |
negative regulation of mitotic cell cycle | biological_process | BCL2, CDKN1B, TIMP2, TGFB1, RB1, SMAD3 |
negative regulation of mitotic cell cycle, embryonic | biological_process | CTNNB1 |
negative regulation of mitotic nuclear division | biological_process | BMP4 |
negative regulation of mitotic recombination | biological_process | MLH1 |
negative regulation of molecular function | biological_process | TWIST1 |
negative regulation of monocyte chemotactic protein-1 production | biological_process | GSTP1 |
negative regulation of monocyte chemotaxis | biological_process | GREM1 |
negative regulation of monocyte differentiation | biological_process | MYC, APCS |
negative regulation of monocyte extravasation | biological_process | PLCB1 |
negative regulation of mononuclear cell proliferation | biological_process | LILRB1 |
negative regulation of mRNA splicing, via spliceosome | biological_process | C1QBP |
negative regulation of mucus secretion | biological_process | ADA |
negative regulation of muscle atrophy | biological_process | MTOR |
negative regulation of muscle cell apoptotic process | biological_process | HMOX1, LIFR |
negative regulation of muscle hyperplasia | biological_process | NOS3 |
negative regulation of muscle hypertrophy | biological_process | MSTN |
negative regulation of muscle organ development | biological_process | IL6 |
negative regulation of muscle tissue development | biological_process | IGFBP5 |
negative regulation of MyD88-independent toll-like receptor signaling pathway | biological_process | TLR4, TLR3 |
negative regulation of myelination | biological_process | IFNG, TNFRSF21, PTEN |
negative regulation of myeloid cell apoptotic process | biological_process | BCL2, MIF |
negative regulation of myeloid cell differentiation | biological_process | GATA2, MEIS1 |
negative regulation of myeloid dendritic cell activation | biological_process | IL10 |
negative regulation of myeloid leukocyte differentiation | biological_process | NME1 |
negative regulation of myoblast differentiation | biological_process | BMP4, NOTCH1, TGFB1, TNF, CXCL10, MSTN, CXCL14, IL18, CCL17 |
negative regulation of myoblast fusion | biological_process | CXCL10 |
negative regulation of myoblast proliferation | biological_process | MSTN |
negative regulation of myosin-light-chain-phosphatase activity | biological_process | TNF |
negative regulation of myotube differentiation | biological_process | NOTCH1, HDAC1 |
negative regulation of NAD(P)H oxidase activity | biological_process | IL13 |
negative regulation of natural killer cell activation | biological_process | MICA |
negative regulation of natural killer cell chemotaxis | biological_process | CCL2, KLRK1 |
negative regulation of natural killer cell mediated cytotoxicity | biological_process | LGALS9, IGF2, MICA, LILRB1 |
negative regulation of necrotic cell death | biological_process | UCN |
negative regulation of neural precursor cell proliferation | biological_process | GATA2, CCR2, IL1B, ID2 |
negative regulation of neuroblast proliferation | biological_process | CTNNA1, TGFB1 |
negative regulation of neurogenesis | biological_process | NOTCH1, WNT7A, IL1B |
negative regulation of neuromuscular junction development | biological_process | PTN |
negative regulation of neuron apoptotic process | biological_process | GCLC, MSH2, BCL2, F2R, ERBB3, BRAF, AXL, CNTF, HMOX1, CCL2, MDK, PIK3CA, BDNF, NTF4, STAR, JUN, SOD1, NGF, APOE, FYN, NRP1, KRAS, BCL2L1, PARK7, NTRK2, HIF1A, TYRO3, BAX, SET, ADAM8, ANGPT1 |
negative regulation of neuron death | biological_process | STAT3, CCL5, AKT1, CTNNB1, SERPINF1, MDK, IL13, ESR1, IGF1, APOE, IL6, PARK7, ESR2, PPARA, SIRT1, UCN |
negative regulation of neuron differentiation | biological_process | SLC6A4, NOTCH1, SOX2, ITGB1, MEIS1, IL1B, HES5, ID2, JAG1 |
negative regulation of neuron maturation | biological_process | GSK3B |
negative regulation of neuron migration | biological_process | GSK3B, STAT3, NRG1 |
negative regulation of neuron projection development | biological_process | GSK3B, VIM, LGALS1, HDAC2, FKBP4 |
negative regulation of neurotrophin TRK receptor signaling pathway | biological_process | AGTR2, SPRY2 |
negative regulation of NF-kappaB transcription factor activity | biological_process | CDKN2A, ANXA4, PSMD10, CAT, TLR9, FOXP3, SIRT1, CYP1B1 |
negative regulation of NFAT protein import into nucleus | biological_process | GSK3B, MTOR |
negative regulation of NIK/NF-kappaB signaling | biological_process | RASSF2, RELA |
negative regulation of nitric oxide biosynthetic process | biological_process | IL10, OPRM1, IL4 |
negative regulation of nitric oxide mediated signal transduction | biological_process | THBS1, SPINK1 |
negative regulation of nitric-oxide synthase activity | biological_process | GSK3B, ENG |
negative regulation of nitric-oxide synthase biosynthetic process | biological_process | PTGER4, GSTP1, EDN1 |
negative regulation of norepinephrine secretion | biological_process | AGTR2, PTGS1, PTGER3, CRH, CRHR2 |
negative regulation of Notch signaling pathway | biological_process | BCL6, GATA2, MMP14, HEY1, DLL4 |
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological_process | TOB1 |
negative regulation of nucleic acid-templated transcription | biological_process | YAP1, APEX1, TOB1, NANOG |
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_process | PTPN22 |
negative regulation of odontogenesis of dentin-containing tooth | biological_process | TNFRSF11B |
negative regulation of oligodendrocyte apoptotic process | biological_process | GAS6 |
negative regulation of oligodendrocyte differentiation | biological_process | BMP4, CTNNB1, NOTCH1, HES5, ID2 |
negative regulation of oocyte development | biological_process | IGF1 |
negative regulation of organ growth | biological_process | SLC6A4, PTEN, PTK2 |
negative regulation of ossification | biological_process | BCL2, NOTCH1, TGFB1, HIF1A |
negative regulation of osteoblast differentiation | biological_process | FGFR1, TOB1, NOTCH1, ID1, IGFBP5, TNF, SMAD3, ID2, TWIST1 |
negative regulation of osteoblast proliferation | biological_process | BCL2, GREM1, SMAD3, AGER |
negative regulation of osteoclast development | biological_process | LTF, LILRB1 |
negative regulation of osteoclast differentiation | biological_process | PIK3R1, CTNNB1, CCL3, FSTL3, TLR4, TLR3, IL4 |
negative regulation of osteoclast proliferation | biological_process | GREM1 |
negative regulation of ovarian follicle development | biological_process | AMH |
negative regulation of oxidative phosphorylation uncoupler activity | biological_process | TWIST1 |
negative regulation of oxidative stress-induced cell death | biological_process | PARK7 |
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological_process | AKT1, HSPB1, GPX1, NFE2L2, SIRT1 |
negative regulation of oxidative stress-induced neuron death | biological_process | PARK7 |
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological_process | PARK7, HIF1A |
negative regulation of oxidoreductase activity | biological_process | HP |
negative regulation of p38MAPK cascade | biological_process | PTPN22 |
negative regulation of pancreatic stellate cell proliferation | biological_process | PPARG |
negative regulation of pathway-restricted SMAD protein phosphorylation | biological_process | ENG, GREM1, SMAD7, DKK1 |
negative regulation of penile erection | biological_process | ADA |
negative regulation of peptidase activity | biological_process | TIMP2, TIMP3, A2M, SERPINA1, NGF, TIMP1, BIRC5, SLPI, SERPINE1, SPINK1, SERPINB2, WFDC2, TIMP4 |
negative regulation of peptide secretion | biological_process | PTGER4, CD74 |
negative regulation of peptidyl-lysine acetylation | biological_process | HDAC2, SIRT1 |
negative regulation of peptidyl-serine phosphorylation | biological_process | RASSF2, HGF, SMAD7, DKK1, BAX |
negative regulation of peptidyl-threonine phosphorylation | biological_process | SMAD7, SPRY2 |
negative regulation of peptidyl-tyrosine phosphorylation | biological_process | SPINK1, ERRFI1 |
negative regulation of peroxisome proliferator activated receptor signaling pathway | biological_process | TWIST1 |
negative regulation of phagocytosis | biological_process | TGFB1, PTEN, ADIPOQ |
negative regulation of phosphatidylinositol 3-kinase signaling | biological_process | PTEN, TWIST1 |
negative regulation of phosphatidylinositol biosynthetic process | biological_process | PDGFA |
negative regulation of phospholipase A2 activity | biological_process | ANXA1 |
negative regulation of phospholipid efflux | biological_process | APOE |
negative regulation of phosphorylation | biological_process | INHBA, BMP4, CDKN1B, CDKN1A, CDKN2A, INHA, AHSG, SIRT1 |
negative regulation of photoreceptor cell differentiation | biological_process | NOTCH1, CNTF |
negative regulation of plasma lipoprotein particle oxidation | biological_process | PON1 |
negative regulation of plasma membrane long-chain fatty acid transport | biological_process | AKT1, THBS1, IRS2 |
negative regulation of plasminogen activation | biological_process | SERPINE1, THBS1, CPB2 |
negative regulation of platelet activation | biological_process | PDGFRA, NOS3, APOE, PDGFA |
negative regulation of platelet aggregation | biological_process | PTGER3 |
negative regulation of platelet-derived growth factor receptor signaling pathway | biological_process | ADIPOQ |
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway | biological_process | ADIPOQ |
negative regulation of positive chemotaxis | biological_process | ANGPT2 |
negative regulation of postsynaptic membrane organization | biological_process | APOE |
negative regulation of potassium ion transmembrane transport | biological_process | PTGER3 |
negative regulation of potassium ion transport | biological_process | NOS3 |
negative regulation of presynaptic membrane organization | biological_process | APOE |
negative regulation of pri-miRNA transcription from RNA polymerase II promoter | biological_process | PPARA |
negative regulation of pro-B cell differentiation | biological_process | NOTCH1, HES5 |
negative regulation of production of miRNAs involved in gene silencing by miRNA | biological_process | ESR1, TGFB1 |
negative regulation of production of siRNA involved in RNA interference | biological_process | TERT |
negative regulation of programmed cell death | biological_process | KIT, PAX2 |
negative regulation of prolactin secretion | biological_process | ANXA5 |
negative regulation of prostaglandin biosynthetic process | biological_process | SIRT1 |
negative regulation of prostatic bud formation | biological_process | BMP4, WNT5A |
negative regulation of proteasomal ubiquitin-dependent protein catabolic process | biological_process | PARK7, FHIT |
negative regulation of protein acetylation | biological_process | PARK7, SIRT1 |
negative regulation of protein autophosphorylation | biological_process | ENG, JUN, ADIPOQ, ERRFI1 |
negative regulation of protein binding | biological_process | GSK3B, ID1, AURKA, SLPI, DKK1, PARK7, BAX, PPARA |
negative regulation of protein catabolic process | biological_process | NOS2, EGFR, FYN, RELA, NRG1, PARK7 |
negative regulation of protein complex assembly | biological_process | GSK3B, CDC42, EIF4EBP1 |
negative regulation of protein complex disassembly | biological_process | TNF |
negative regulation of protein export from nucleus | biological_process | TXN, PARK7 |
negative regulation of protein homodimerization activity | biological_process | ID1 |
negative regulation of protein homooligomerization | biological_process | SRC, CLU, CLDN7 |
negative regulation of protein import into nucleus | biological_process | ANGPT1 |
negative regulation of protein import into nucleus, translocation | biological_process | GAS6 |
negative regulation of protein K48-linked deubiquitination | biological_process | PARK7 |
negative regulation of protein kinase activity | biological_process | BGN, AKT1, GSTP1, HSPB1, RB1, SOCS3, IL6, PARK7, CDKN2A, CEP85, DCN |
negative regulation of protein kinase activity by protein phosphorylation | biological_process | AKT1 |
negative regulation of protein kinase B signaling | biological_process | XDH, DRD2, PDCD6, MSTN, PTEN, SIRT1, GPER1 |
negative regulation of protein localization to cell surface | biological_process | ASTN2 |
negative regulation of protein localization to nucleus | biological_process | GSK3B |
negative regulation of protein localization to plasma membrane | biological_process | TGFB1 |
negative regulation of protein oligomerization | biological_process | HIST3H3 |
negative regulation of protein phosphorylation | biological_process | XDH, FBLN1, IGFBP3, CCNB1, MTOR, INSR, TGFB1, PTEN, PARK7, AGER, IL2, ANGPT1 |
negative regulation of protein secretion | biological_process | DRD2, ANXA1 |
negative regulation of protein serine/threonine kinase activity | biological_process | HSPB1 |
negative regulation of protein sumoylation | biological_process | CTNNB1, PARK7, PIAS3 |
negative regulation of protein ubiquitination | biological_process | GCLC, MTOR, FYN, SMAD7, PARK7 |
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological_process | WNT1, CDKN2A |
negative regulation of proteolysis | biological_process | AKT1, TIMP2, TIMP3, PLAT |
negative regulation of proteolysis involved in cellular protein catabolic process | biological_process | CDKN2A |
negative regulation of Ras protein signal transduction | biological_process | TIMP2, SPRY2, TGFB2 |
negative regulation of reactive oxygen species metabolic process | biological_process | BCL2, BRCA1, CRYAB, HIF1A, ESR2, PAX2 |
negative regulation of receptor binding | biological_process | ANXA2, ADIPOQ |
negative regulation of receptor biosynthetic process | biological_process | PPARG, PPARA |
negative regulation of receptor internalization | biological_process | ANXA2 |
negative regulation of receptor-mediated endocytosis | biological_process | RAC1 |
negative regulation of reciprocal meiotic recombination | biological_process | MSH2 |
negative regulation of regulatory T cell differentiation | biological_process | CTLA4 |
negative regulation of release of cytochrome c from mitochondria | biological_process | AKT1, HGF, IGF1, PSMD10, GPX1, BCL2L1 |
negative regulation of release of sequestered calcium ion into cytosol | biological_process | TGFB1 |
negative regulation of renal albumin absorption | biological_process | GAS6 |
negative regulation of renal phosphate excretion | biological_process | STC1 |
negative regulation of renal sodium excretion | biological_process | COMT |
negative regulation of renin secretion into blood stream | biological_process | F2R |
negative regulation of response to cytokine stimulus | biological_process | APOA1 |
negative regulation of retinal cell programmed cell death | biological_process | BCL2 |
negative regulation of retinoic acid biosynthetic process | biological_process | AKR1C3 |
negative regulation of retinoic acid receptor signaling pathway | biological_process | CYP26A1, EZH2 |
negative regulation of Rho protein signal transduction | biological_process | BCL6, ITGA3, ITGB1 |
negative regulation of ribosome biogenesis | biological_process | PTEN |
negative regulation of RIG-I signaling pathway | biological_process | C1QBP |
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological_process | ID1 |
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly | biological_process | HMGB1 |
negative regulation of satellite cell differentiation | biological_process | MSTN |
negative regulation of Schwann cell proliferation | biological_process | DICER1 |
negative regulation of secretion | biological_process | ERBB3, EGF, NRG1 |
negative regulation of sequence-specific DNA binding transcription factor activity | biological_process | ID1, HMOX1, ESR1, SMAD7, RB1, HDAC2, GAS6, FOXP3, EZH2, SIRT1, ID2, TWIST1, NR0B2, SFRP4 |
negative regulation of sequestering of triglyceride | biological_process | PPARG, PPARA |
negative regulation of serine-type endopeptidase activity | biological_process | SPINK1 |
negative regulation of serotonin secretion | biological_process | LILRB1 |
negative regulation of signal transduction | biological_process | GSK3B, IGFBP3, ERBB3, SOCS3, IHH |
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological_process | HMGA2 |
negative regulation of single-species biofilm formation in or on host organism | biological_process | LTF |
negative regulation of skeletal muscle hypertrophy | biological_process | IGFBP5 |
negative regulation of skeletal muscle satellite cell proliferation | biological_process | MSTN |
negative regulation of skeletal muscle tissue development | biological_process | TGFB1, DKK1, TWIST1 |
negative regulation of skeletal muscle tissue growth | biological_process | MSTN |
negative regulation of small intestine smooth muscle contraction | biological_process | PTGER4 |
negative regulation of smooth muscle cell apoptotic process | biological_process | GSK3B, IGF1, EDN1 |
negative regulation of smooth muscle cell chemotaxis | biological_process | AIF1 |
negative regulation of smooth muscle cell migration | biological_process | IGFBP3, APEX1, IGFBP5, SERPINE1, ADIPOQ |
negative regulation of smooth muscle cell proliferation | biological_process | PPARG, IGFBP3, IL12B, IGFBP5, HMOX1, IL15, COMT, IL12A, ESR1, ANG, IFNG, ADIPOQ, AIF1, ESR2 |
negative regulation of smooth muscle cell-matrix adhesion | biological_process | SERPINE1 |
negative regulation of smooth muscle contraction | biological_process | PTGS2 |
negative regulation of smoothened signaling pathway | biological_process | RB1 |
negative regulation of sodium-dependent phosphate transport | biological_process | SFRP4 |
negative regulation of stem cell differentiation | biological_process | YAP1, NOTCH1, HES5, JAG1 |
negative regulation of stem cell proliferation | biological_process | FBLN1 |
negative regulation of steroid biosynthetic process | biological_process | WNT4 |
negative regulation of stress-activated MAPK cascade | biological_process | GSTP1, MYC, FOXO1 |
negative regulation of striated muscle cell differentiation | biological_process | EZH2 |
negative regulation of striated muscle tissue development | biological_process | BMP4, SOX15, TWIST1 |
negative regulation of substrate adhesion-dependent cell spreading | biological_process | FBLN1, ACTN4, POSTN |
negative regulation of synapse assembly | biological_process | WNT5A, DKK1, PTK2 |
negative regulation of synaptic transmission | biological_process | BCHE, PCDH17, ADIPOQ |
negative regulation of synaptic transmission, dopaminergic | biological_process | SLC6A4, PTGS2 |
negative regulation of synaptic transmission, glutamatergic | biological_process | DRD2 |
negative regulation of synaptic vesicle clustering | biological_process | PTEN |
negative regulation of synaptic vesicle exocytosis | biological_process | BRAF |
negative regulation of T cell activation | biological_process | TGFB1, IL4, PTPN22 |
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological_process | LGALS3, LILRB1 |
negative regulation of T cell apoptotic process | biological_process | CCL5, IDO1 |
negative regulation of T cell cytokine production | biological_process | FOXP3 |
negative regulation of T cell differentiation | biological_process | CD74 |
negative regulation of T cell differentiation in thymus | biological_process | BMP4, IHH |
negative regulation of T cell mediated cytotoxicity | biological_process | LILRB1 |
negative regulation of T cell proliferation | biological_process | IL10, HLA-DRB1, IDO1, HLA-G, TGFB1, TNFRSF21, IL2RA, FOXP3, IL20RB, LILRB1 |
negative regulation of T cell receptor signaling pathway | biological_process | LGALS3, PTPN22 |
negative regulation of T-helper 1 type immune response | biological_process | IL33, IL1RL1 |
negative regulation of T-helper 17 cell differentiation | biological_process | IL4, FOXP3 |
negative regulation of T-helper 2 cell differentiation | biological_process | BCL6, ANXA1 |
negative regulation of telomerase activity | biological_process | SRC, PPARG, TP53 |
negative regulation of telomere capping | biological_process | ATM |
negative regulation of telomere maintenance via telomerase | biological_process | SRC |
negative regulation of testicular blood vessel morphogenesis | biological_process | WNT4 |
negative regulation of testosterone biosynthetic process | biological_process | WNT4 |
negative regulation of thymocyte apoptotic process | biological_process | BMP4, ADA, HIF1A |
negative regulation of toll-like receptor 3 signaling pathway | biological_process | F2RL1 |
negative regulation of toll-like receptor signaling pathway | biological_process | TYRO3, TLR9 |
negative regulation of TOR signaling | biological_process | PDCD6, HIF1A, SIRT1 |
negative regulation of TORC1 signaling | biological_process | ATM |
negative regulation of TRAIL-activated apoptotic signaling pathway | biological_process | PARK7 |
negative regulation of transcription by competitive promoter binding | biological_process | MUC1, SMAD7 |
negative regulation of transcription by transcription factor localization | biological_process | ID1 |
negative regulation of transcription elongation from RNA polymerase II promoter | biological_process | EZH2 |
negative regulation of transcription factor import into nucleus | biological_process | CD36 |
negative regulation of transcription from RNA polymerase II promoter | biological_process | FGFR1, EGR1, TXN, GATA3, CCND1, VEGFA, BCL6, STAT3, NR2F2, BMP4, DNMT1, HMGA2, PPARG, FGFR2, HMGB1, CD36, LEP, CTNNB1, ATF2, NFKB1, NOTCH1, ID1, FASLG, VDR, ENG, FST, GATA2, STAT6, WT1, HNF1B, EFNA1, BMP6, SOX2, ZEB1, ESR1, IFNG, TGFB1, TP53, SUV39H1, TNF, MYC, ENO1, SMAD7, RB1, ARID1A, SOX15, KLF11, SNAI1, DKK1, PRDM1, PSMD10, IL1B, EDN1, C1QBP, RUNX3, PLK1, HDAC2, SMAD3, RELA, DICER1, DNMT3A, FOXL2, HIF1A, HES5, FOXO1, HSF1, SMAD2, HEY1, ESR2, PPARA, NFKB2, POU5F1, HDAC1, FOXP3, EZH2, SIRT1, ID2, SMAD4, EHMT2, TWIST1, DNMT3B, NR0B2, ZNF366, TP63, KLF10, GATA6, SUV39H2, DLL4, HAMP, NODAL, AHRR, MAF, MBD2 |
negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle | biological_process | RB1 |
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological_process | JUN |
negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | biological_process | HEY1 |
negative regulation of transcription involved in G1/S transition of mitotic cell cycle | biological_process | RB1 |
negative regulation of transcription regulatory region DNA binding | biological_process | HEY1, PPARA |
negative regulation of transcription, DNA-templated | biological_process | GCLC, SRC, GATA3, BCL6, NR2F2, BMP4, DNMT1, WNT5A, HMGA2, PPARG, CTNNB1, BRCA1, NFKB1, HMGA1, AHR, CDKN1B, NOTCH1, ID1, CDKN2A, VDR, WT1, ZEB1, GREM1, JUN, TGFB1, CLOCK, TP53, SUV39H1, TNF, BIRC5, ENO1, SMAD7, RB1, KLF11, SNAI1, IL4, HDAC2, RELA, NRG1, FOXL2, FOXP1, HES5, FOXO1, GAS6, PLCB1, SMAD2, HEY1, ADIPOQ, SET, HDAC1, FOXP3, EZH2, SIRT1, ID2, SMAD4, TWIST1, DNMT3B, NR0B2, TP63, KLF10, GATA6, SUV39H2, PAX2, WNT4, DNMT3L, TBPL2, MBD2 |
negative regulation of transformation of host cell by virus | biological_process | FBLN1 |
negative regulation of transforming growth factor beta production | biological_process | IL13 |
negative regulation of transforming growth factor beta receptor signaling pathway | biological_process | ENG, TGFB1, SMAD7, TGFB1I1, WNT1, SMAD3, SMAD2, SIRT1, ADAM17, HTRA1 |
negative regulation of transforming growth factor beta1 production | biological_process | GATA6 |
negative regulation of transforming growth factor beta2 production | biological_process | CDH3, GATA6 |
negative regulation of transforming growth factor-beta secretion | biological_process | FBLN1, FN1, LILRB1 |
negative regulation of translation | biological_process | TOB1, IGFBP5, TIA1, WT1, ANG, EIF4EBP1, DAPK1 |
negative regulation of translational initiation | biological_process | EIF3E, EIF4EBP1 |
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological_process | FSTL3 |
negative regulation of transporter activity | biological_process | INSR |
negative regulation of triglyceride metabolic process | biological_process | ESR1 |
negative regulation of trophoblast cell migration | biological_process | TIMP1, NODAL |
negative regulation of tumor necrosis factor (ligand) superfamily member 11 production | biological_process | LTF |
negative regulation of tumor necrosis factor biosynthetic process | biological_process | IL10, GHRL, ERRFI1, LILRB1 |
negative regulation of tumor necrosis factor production | biological_process | IL10, PTGER4, AXL, GSTP1, LGALS9, TLR4, GAS6, HSF1, ADIPOQ, FOXP3, PTPN22, TWIST1 |
negative regulation of tumor necrosis factor secretion | biological_process | PTGER4 |
negative regulation of tumor necrosis factor-mediated signaling pathway | biological_process | GSTP1, APOA1, GAS6, F2RL1, ADIPOQ |
negative regulation of type 2 immune response | biological_process | BCL6, STAT6, CCR2 |
negative regulation of type B pancreatic cell development | biological_process | GSK3B |
negative regulation of type IV hypersensitivity | biological_process | IL20RB |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | biological_process | CCNB1, PSMD9, PSMD10 |
negative regulation of ubiquitin-protein transferase activity | biological_process | SMAD7, PARK7, LIMK1, CDKN2A |
negative regulation of ubiquitin-specific protease activity | biological_process | PARK7 |
negative regulation of vascular endothelial growth factor receptor signaling pathway | biological_process | PDCD6 |
negative regulation of vascular endothelial growth factor signaling pathway | biological_process | XDH, DCN |
negative regulation of vascular permeability | biological_process | ADM, ANGPT1 |
negative regulation of vascular smooth muscle cell proliferation | biological_process | CDKN1B, GPER1 |
negative regulation of vascular wound healing | biological_process | SERPINE1 |
negative regulation of vasculogenesis | biological_process | XDH |
negative regulation of vasoconstriction | biological_process | LEP, ADM, HIF1A, CX3CL1 |
negative regulation of vasodilation | biological_process | CRP |
negative regulation of very-low-density lipoprotein particle remodeling | biological_process | APOA1, APOA2 |
negative regulation of viral entry into host cell | biological_process | PTX3, APCS |
negative regulation of viral genome replication | biological_process | CCL5, LTF, TNF, SLPI, ISG20 |
negative regulation of viral process | biological_process | MBL2, LTF, APCS |
negative regulation of vitamin D biosynthetic process | biological_process | NFKB1, SNAI1 |
negative regulation of voltage-gated calcium channel activity | biological_process | CRHR1, DRD2 |
negative regulation of white fat cell proliferation | biological_process | IL4 |
negative regulation of Wnt protein secretion | biological_process | OPRM1 |
negative regulation of Wnt signaling pathway | biological_process | CCND1, DKK1, SFRP4 |
negative regulation of Wnt-Frizzled-LRP5/6 complex assembly | biological_process | DKK1 |
negative regulation of wound healing | biological_process | FGF2, GJA1, SERPINE1, APCS, SMAD3, WNT4 |
negative thymic T cell selection | biological_process | FAS, CD74, CCR7 |
nephric duct development | biological_process | HNF1B |
nephric duct formation | biological_process | GATA3, HNF1B, PAX2 |
nephric duct morphogenesis | biological_process | GATA3 |
nephrogenic mesenchyme morphogenesis | biological_process | SMAD4 |
nephron development | biological_process | ITGA3, JAG1, WNT4 |
nephron tubule formation | biological_process | CTNNB1 |
nerve development | biological_process | NRP1, NRP2, DICER1, SEMA3A |
nerve growth factor processing | biological_process | NGF, PCSK5 |
nervous system development | biological_process | GSK3B, GATA3, INHBA, FGF2, VEGFA, STAT3, AKT1, CTNNB1, NME1, CNTF, CXCL1, STMN1, PTN, MDK, BDNF, L1CAM, ZEB1, INHA, ERBB2, ARID1A, NRP1, FOS, MSI1, KALRN, NRP2, CDC42, PTEN, NRG1, NTRK2, HES5, DPYSL2, BAX, LIMK1, GPER1, JAG1, IGSF8, PTPRR, NAGLU, DLX5, DLL4, SEMA3A, CHD5, NODAL, OLFM1, SEMA3C |
netrin-activated signaling pathway | biological_process | PTK2 |
neural crest cell development | biological_process | MAPK1, EDNRA, EDN1, NRG1 |
neural crest cell differentiation | biological_process | SMAD4 |
neural crest cell migration | biological_process | KITLG, LAMA5, HIF1A, SEMA3A, SEMA3C |
neural crest cell migration involved in autonomic nervous system development | biological_process | NRP1, SEMA3A |
neural crest cell migration involved in heart formation | biological_process | FOLR1 |
neural crest cell migration involved in sympathetic nervous system development | biological_process | SEMA3A |
neural fold elevation formation | biological_process | HIF1A |
neural fold formation | biological_process | NODAL |
neural nucleus development | biological_process | HOXB2 |
neural plate development | biological_process | CTNNB1 |
neural tube closure | biological_process | BMP4, WNT5A, SDC4, ADM, ARID1A, TWIST1, PAX2 |
neural tube development | biological_process | WNT5A, NOTCH1, HES5, SEMA3C |
neuroblast differentiation | biological_process | BCHE |
neurofilament cytoskeleton organization | biological_process | SOD1 |
neurogenesis | biological_process | WNT5A, WNT2, WNT1, NRG1 |
neurological system process involved in regulation of systemic arterial blood pressure | biological_process | DRD2 |
neuromuscular junction development | biological_process | TNC, ERBB2, COL4A1, NTRK2 |
neuromuscular process | biological_process | UCHL1 |
neuromuscular synaptic transmission | biological_process | P2RX3 |
neuron apoptotic process | biological_process | BCL2, ERBB3, CASP3, FAS, RB1, TNFRSF21, BCL2L1, BAX, ATM, TP63 |
neuron cellular homeostasis | biological_process | TYRO3 |
neuron death | biological_process | CCR2, PLAU |
neuron development | biological_process | CNTF, LIF, NRP1, WNT1, TGFB2 |
neuron differentiation | biological_process | GATA3, DNMT1, WNT5A, SHC1, CTNNB1, WNT2, NOTCH1, ID1, CASP3, GATA2, EFNA1, RB1, DNMT3A, NTRK2, HES5, EMX2, PTPRR, WNT4 |
neuron fate commitment | biological_process | BMP4, NOTCH1, GATA2, WNT1, TGFB2, NRG1, ID2, SMAD4 |
neuron fate determination | biological_process | WNT1, CDC42 |
neuron maturation | biological_process | RB1 |
neuron migration | biological_process | FGFR1, GATA3, NR2F2, ITGA3, GJA1, CTNNB1, AXL, GATA2, CXCL12, HSP90AA1, FYN, NRP1, PTK2, NTRK2, GAS6, BAX, CXCR4, TWIST1, SEMA3A |
neuron projection development | biological_process | FGFR1, CDH1, HMGB1, SHC1, MAP2, NCAM1, STMN1, TNC, ITGB1, RB1, IL6, PTEN, AGER, UCN, NPY |
neuron projection extension | biological_process | AURKA, POSTN |
neuron projection morphogenesis | biological_process | WNT5A, CLU, GJA1, LIFR, NTF4, NGF, SGK1, RAC1, DICER1, PAK1, ATP7A |
neuron projection regeneration | biological_process | ADM, APOA1, APOE |
neuron recognition | biological_process | CXCR4 |
neuron remodeling | biological_process | NTN4 |
neuron-neuron synaptic transmission | biological_process | DRD2, PTEN |
neuronal action potential | biological_process | GPER1, P2RX3 |
neuronal signal transduction | biological_process | OLFM1 |
neuronal stem cell population maintenance | biological_process | NOTCH1, SOX2, HES5, FOXO1, JAG1, MMP24 |
neuropeptide signaling pathway | biological_process | OPRM1, SSTR1, UCN, KISS1R, NPY |
neurotransmitter catabolic process | biological_process | MAOA, COMT |
neurotransmitter metabolic process | biological_process | MAOA |
neurotransmitter receptor metabolic process | biological_process | NRG1 |
neurotransmitter secretion | biological_process | WNT7A |
neurotransmitter transport | biological_process | SLC6A4, SLC6A2 |
neurotrophin signaling pathway | biological_process | NTRK2 |
neurotrophin TRK receptor signaling pathway | biological_process | SRC, CASP3, NGF |
neutral lipid catabolic process | biological_process | LIPC |
neutrophil activation | biological_process | CCL5, CXCL8, CXCR2, F2RL1 |
neutrophil activation involved in immune response | biological_process | FCER1G |
neutrophil apoptotic process | biological_process | IFNG, IL6 |
neutrophil chemotaxis | biological_process | CCL5, LGALS3, CXCL8, CCL3, SAA1, CXCR2, CCL2, FCER1G, IFNG, CCL25, CCL22, CCL16, IL1B, ITGB2, EDN1, TGFB2, CCL7, CX3CL1, CCL17, CCL11 |
neutrophil clearance | biological_process | HMGB1, ANXA1 |
neutrophil homeostasis | biological_process | ANXA1 |
neutrophil mediated immunity | biological_process | ACE, IL6R, CXCL5, IL6, ADAM17, CXCL6 |
neutrophil mediated killing of gram-positive bacterium | biological_process | CTSG |
NFAT protein import into nucleus | biological_process | PIK3R1 |
nicotinamide metabolic process | biological_process | PTGS2 |
nicotinamide riboside catabolic process | biological_process | PNP |
NIK/NF-kappaB signaling | biological_process | NFKB1, PSMD9, PSMD10, NFKB2 |
nitric oxide biosynthetic process | biological_process | NOS2, AKT1, NOS3, ARG2, CYP1B1 |
nitric oxide mediated signal transduction | biological_process | NOS2, CD36, FPR1, AGTR2, NOS3, APOE |
nitric oxide production involved in inflammatory response | biological_process | TLR4 |
nitric oxide storage | biological_process | GSTP1 |
nitric oxide transport | biological_process | EDN1 |
nitrobenzene metabolic process | biological_process | GSTM1 |
NK T cell proliferation | biological_process | IL15 |
NMDA glutamate receptor clustering | biological_process | APOE |
nodal signaling pathway | biological_process | SMAD3, SMAD2, NODAL |
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological_process | NODAL |
non-canonical Wnt signaling pathway | biological_process | WNT5A, WNT7A, RAC1, WNT4, SFRP4 |
non-canonical Wnt signaling pathway via JNK cascade | biological_process | WNT5A |
non-canonical Wnt signaling pathway via MAPK cascade | biological_process | WNT4 |
norepinephrine biosynthetic process | biological_process | GATA3 |
norepinephrine metabolic process | biological_process | AKR1B1, ATP7A |
norepinephrine transport | biological_process | SLC6A2 |
Notch receptor processing | biological_process | ADAM17, JAG1, DLL4, NOTCH4 |
Notch signaling involved in heart development | biological_process | NOTCH1, SNAI1, HEY1, JAG1, DLL4 |
Notch signaling pathway | biological_process | KRT19, CDKN1B, NOTCH1, ANXA4, HNF1B, MDK, TGFB1, MYC, PTP4A3, IL2RA, FCER2, HES5, HEY1, KAT2B, ADAM17, NR0B2, TP63, JAG1, DLL4, NOTCH4, TIMP4 |
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation | biological_process | NOTCH1 |
notochord development | biological_process | YAP1 |
notochord formation | biological_process | EFNA1 |
notochord morphogenesis | biological_process | WNT5A |
nuclear fragmentation involved in apoptotic nuclear change | biological_process | GPER1 |
nuclear migration | biological_process | CDC42 |
nuclear transport | biological_process | HMGA1 |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | biological_process | EIF3E, RPL41 |
nuclear-transcribed mRNA poly(A) tail shortening | biological_process | MLH1 |
nucleic acid phosphodiester bond hydrolysis | biological_process | ANG, PMS2 |
nucleobase-containing compound metabolic process | biological_process | PNP, DPYSL2 |
nucleobase-containing small molecule interconversion | biological_process | TXN, NME1 |
nucleocytoplasmic transport | biological_process | SET |
nucleoside diphosphate phosphorylation | biological_process | NME1 |
nucleoside metabolic process | biological_process | PNP |
nucleoside triphosphate biosynthetic process | biological_process | NME1 |
nucleosome assembly | biological_process | H2AFX, SET, HIST3H3, HIST2H3A |
nucleosome disassembly | biological_process | HMGA1, ARID1A, SET |
nucleosome mobilization | biological_process | ARID1A |
nucleotide metabolic process | biological_process | NME1, ADA, FHIT |
nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_process | RELA, NOD2 |
nucleotide-binding oligomerization domain containing signaling pathway | biological_process | MAP3K7, NOD2, NOD1 |
nucleotide-excision repair | biological_process | BRCA2, TP53, OGG1 |
nucleotide-excision repair, DNA damage recognition | biological_process | COPS5 |
nucleotide-excision repair, DNA gap filling | biological_process | PCNA, XRCC1 |
nucleotide-excision repair, DNA incision | biological_process | PCNA, OGG1 |
nucleotide-excision repair, DNA incision, 5'-to lesion | biological_process | PCNA |
nucleus localization | biological_process | CDC42 |
nucleus organization | biological_process | PRM1 |
O-glycan processing | biological_process | MUC1, MUC16, MUC17, MUC4 |
obsolete transformed cell apoptotic process | biological_process | TNF, BAX |
odontogenesis | biological_process | INHBA, BMP4, FGFR2, CSF1, SDC1, TGFB2, TWIST1, AQP5 |
odontogenesis of dentin-containing tooth | biological_process | ITGA6, BMP4, CTNNB1, CTNNA1, TNC, ADM, BSG, CA2, LAMA5, BCL2L11, HDAC2, BAX, HDAC1, TP63 |
olfactory bulb development | biological_process | CSF1R, DPYSL2, ID2, SEMA3A |
olfactory bulb interneuron development | biological_process | WNT5A |
olfactory pit development | biological_process | DLX5 |
oligodendrocyte apoptotic process | biological_process | TP53, TNFRSF21 |
oligodendrocyte development | biological_process | GSTP1, TGFB1, HES5, ID2 |
oligodendrocyte differentiation | biological_process | NOTCH1, ERBB2, NRG1, NTRK2 |
omega-hydroxylase P450 pathway | biological_process | CYP2C19, CYP1A2, CYP1A1, CYP1B1 |
oncogene-induced cell senescence | biological_process | HMGA2, HMGA1 |
oncostatin-M-mediated signaling pathway | biological_process | IL6ST, LIFR |
one-carbon metabolic process | biological_process | MAT2A, CA2 |
oocyte development | biological_process | BCL2, CTNNB1, ATM, WNT4 |
oocyte differentiation | biological_process | LGR5 |
oocyte growth | biological_process | GDF9, FOXL2 |
oocyte maturation | biological_process | CCNB1, BRCA2, ANG |
oogenesis | biological_process | MLH1, SRC |
operant conditioning | biological_process | TACR2, TACR1 |
opioid receptor signaling pathway | biological_process | OPRM1 |
opsonization | biological_process | MBL2, PTX3, CRP |
optic chiasma development | biological_process | PAX2 |
optic cup formation involved in camera-type eye development | biological_process | WNT5A, ARID1A |
optic cup morphogenesis involved in camera-type eye development | biological_process | PAX2 |
optic nerve development | biological_process | PAX2 |
optic nerve morphogenesis | biological_process | PAX2 |
optic nerve structural organization | biological_process | PAX2 |
orbitofrontal cortex development | biological_process | FGFR1, FGFR2, DRD2 |
organ growth | biological_process | BCL2, FGFR2, SMAD2 |
organ induction | biological_process | FGFR1, BMP4, HOXA11, FGF1 |
organelle transport along microtubule | biological_process | CDC42 |
organic acid metabolic process | biological_process | STAR, CYP17A1 |
organic anion transport | biological_process | SLC22A23 |
organic substance metabolic process | biological_process | PGM1 |
organophosphate catabolic process | biological_process | PON1 |
ossification | biological_process | BCL2, BMP4, MMP13, ALOX15, MMP9, RASSF2, SPP1, CSF1, SPARC, MMP14, PTN, BMP6, EGFR, FSTL3, AHSG, LTF, IGF2, COL5A2, RUNX3, TWIST1, DLX5, STC1 |
ossification involved in bone maturation | biological_process | RHOA |
ossification involved in bone remodeling | biological_process | TGFB1 |
osteoblast development | biological_process | ESR1, SMAD3 |
osteoblast differentiation | biological_process | BMP4, MMP13, GJA1, IGFBP3, AKT1, CCL3, SPP1, IGFBP5, VCAN, BMP6, TNC, SOX2, ATP5B, CYR61, SNAI1, CAT, SMAD3, TWIST1, DLX5, CYP24A1, CREB3L1 |
osteoclast development | biological_process | SRC, ANXA2, FOXP1 |
osteoclast differentiation | biological_process | CTNNB1, CSF1, TNF, CSF1R, FOXP1 |
osteoclast proliferation | biological_process | CSF1 |
otic placode formation | biological_process | NRP1 |
otic vesicle development | biological_process | GATA3 |
otic vesicle formation | biological_process | FGFR2 |
outer ear morphogenesis | biological_process | FGFR1, MAPK1, TWIST1 |
outer mitochondrial membrane organization | biological_process | BAX |
outflow tract morphogenesis | biological_process | VEGFA, ATF2, JUN, CLDN5, HIF1A, SEMA3C |
outflow tract septum morphogenesis | biological_process | FGFR2, GATA6 |
ovarian cumulus expansion | biological_process | BMPR1B |
ovarian follicle atresia | biological_process | FAS |
ovarian follicle development | biological_process | BCL2, INHBA, VEGFA, BMP4, KIT, AHR, CTNNA1, KITLG, MMP14, ANG, SOD1, INHA, CAPN5, FSHB, ICAM1, BCL2L1, FOXL2, BAX, ESR2, SMAD4 |
oviduct development | biological_process | CTNNB1, WNT7A |
ovulation | biological_process | HPGD, IL1R1, PTGS2, CYP17A1, IL1B |
ovulation cycle | biological_process | SERPINF1, AXL, FAS, BMPR1B, TYRO3, TIMP4 |
ovulation cycle process | biological_process | LHCGR, MSTN |
ovulation from ovarian follicle | biological_process | PLA2G4A, LEP, NOS3, SIRT1 |
oxalate transport | biological_process | SLC26A8 |
oxaloacetate metabolic process | biological_process | ACLY |
oxidation-reduction process | biological_process | XDH, AKR1B1, NDUFS1, AKR1D1, TXN, NOS2, PRDX6, APEX1, ALOX15, GPX3, CYP19A1, HPGD, MTHFR, CYP2A6, HMOX1, HSD3B2, HSD17B1, IDO1, VCAM1, CYP2B6, MAOA, LPO, PTGS1, NOS3, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, HSD17B2, AKR1C3, ALDH3A2, AKR1C2, CYP17A1, MT-CO2, CYP2E1, CYP11A1, SOD1, CYP1A2, ABCC4, CYP26A1, CP, GPX1, CAT, CYP1A1, MPO, ADI1, LOXL4, PAX2, AKR1C1, HSD17B7, HSD11B2, LOXL1, CYP1B1, PTGES2, TET3, SRD5A1, CYP24A1, TET2, TET1 |
oxidative deethylation | biological_process | CYP1A2 |
oxidative demethylation | biological_process | CYP1A2 |
oxidative phosphorylation | biological_process | MSH2 |
oxidative stress-induced premature senescence | biological_process | TP53 |
oxygen homeostasis | biological_process | HIF1A |
oxygen transport | biological_process | MYC |
p38MAPK cascade | biological_process | LGALS9 |
palate development | biological_process | INHBA, WNT5A, CLDN5, WNT7A, SNAI1, SMAD2, SMAD4, TWIST1, DLX5 |
pancreas development | biological_process | CTNNB1, SMAD2, GATA6 |
pancreas morphogenesis | biological_process | NR5A2 |
pancreatic A cell differentiation | biological_process | GATA6 |
pancreatic juice secretion | biological_process | UCN, AQP5 |
paramesonephric duct development | biological_process | WNT4 |
parathyroid gland development | biological_process | GATA3 |
parathyroid hormone secretion | biological_process | GATA3 |
paraxial mesoderm development | biological_process | FGFR1, YAP1 |
paraxial mesoderm formation | biological_process | WNT5A |
paraxial mesoderm morphogenesis | biological_process | SMAD3, SMAD2 |
parturition | biological_process | CRHR1, MMP13, HPGD, PTGFR, CRH |
pathway-restricted SMAD protein phosphorylation | biological_process | TGFB1, SMAD7, TGFB2 |
pattern recognition receptor signaling pathway | biological_process | CD36 |
pattern specification process | biological_process | CDX1, ZEB1, SMAD2, TP63 |
penile erection | biological_process | EDNRA |
pentacyclic triterpenoid metabolic process | biological_process | IL1B |
peptide antigen assembly with MHC class II protein complex | biological_process | HLA-DRB1, HLA-DRA |
peptide biosynthetic process | biological_process | PCSK5 |
peptide catabolic process | biological_process | MMP13, ACE |
peptide cross-linking | biological_process | FN1, ANXA1, THBS1 |
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan | biological_process | BGN, SPOCK2, DCN |
peptide hormone processing | biological_process | CGA, FSHB, LHB, PCSK5 |
peptide hormone secretion | biological_process | EDN1, SMPD3 |
peptide metabolic process | biological_process | MME, CMA1 |
peptidyl-cysteine S-nitrosylation | biological_process | NOS2 |
peptidyl-lysine acetylation | biological_process | KAT2B, SIRT1 |
peptidyl-lysine deacetylation | biological_process | SIRT1 |
peptidyl-lysine dimethylation | biological_process | EHMT2 |
peptidyl-lysine modification | biological_process | ATP7A |
peptidyl-methionine modification | biological_process | APOA1, APOA2 |
peptidyl-serine autophosphorylation | biological_process | ATM |
peptidyl-serine phosphorylation | biological_process | GSK3B, BCL2, SRC, MAPK1, AKT1, TDGF1, MTOR, CHEK2, PRKCB, SGK1, PLK1, GAS6, ATM |
peptidyl-threonine phosphorylation | biological_process | GSK3B, BCL2, MAPK1, AKT1, MTOR |
peptidyl-tyrosine autophosphorylation | biological_process | SRC, KDR, JAK1, TYK2, INSR, IGF1R, FYN, PTK2 |
peptidyl-tyrosine dephosphorylation | biological_process | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR |
peptidyl-tyrosine phosphorylation | biological_process | FGFR1, SRC, FGF2, MET, FGFR2, KIT, ERBB3, KDR, FLT4, CSF2RB, PDGFRA, AXL, FLT1, FLT3, INSR, HSP90AA1, EGFR, FGF1, ERBB2, FYN, MAP2K7, EGF, CSF2, IL5, CSF1R, PTK2, NRG1, NTRK2, TYRO3, TEK, MST1R |
pericardium development | biological_process | SMAD3, SMAD2 |
pericardium morphogenesis | biological_process | WNT5A, NOTCH1, DLL4 |
peripheral nervous system axon regeneration | biological_process | TNC, APOA1 |
peripheral nervous system development | biological_process | ERBB3, ALDH3A2, ERBB2, NRG1 |
peripheral nervous system myelin formation | biological_process | DICER1 |
peripheral nervous system myelin maintenance | biological_process | AKT1, SOD1 |
peripheral nervous system neuron development | biological_process | RUNX3, NTRK2 |
peristalsis | biological_process | DRD2, P2RX3 |
PERK-mediated unfolded protein response | biological_process | CXCL8, IGFBP1, CCL2, NFE2L2 |
peroxisome proliferator activated receptor signaling pathway | biological_process | PPARG, ACTN4 |
Peyer's patch development | biological_process | ADA, ID2 |
phagocytosis | biological_process | AXL, GATA2, PECAM1, PIK3CA, ANXA1, GAS6 |
phagocytosis, engulfment | biological_process | FCER1G, RAC1, AIF1 |
phagocytosis, recognition | biological_process | CD36, SCARB1 |
pharyngeal arch artery morphogenesis | biological_process | FOLR1 |
pharyngeal system development | biological_process | GATA3 |
phenol-containing compound metabolic process | biological_process | STAR, CYP17A1 |
phenylethylamine metabolic process | biological_process | MAOA |
phosphate ion homeostasis | biological_process | SFRP4 |
phosphate-containing compound metabolic process | biological_process | TGFB1 |
phosphatidic acid biosynthetic process | biological_process | PLA2G4A, PLA2G2A |
phosphatidic acid metabolic process | biological_process | LIPC, PLA2G2A |
phosphatidylcholine acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
phosphatidylcholine biosynthetic process | biological_process | APOA1, APOA2, PEMT |
phosphatidylcholine catabolic process | biological_process | LIPC |
phosphatidylcholine metabolic process | biological_process | CETP, LIPC, PON1 |
phosphatidylethanolamine acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
phosphatidylethanolamine biosynthetic process | biological_process | ALOX15 |
phosphatidylethanolamine metabolic process | biological_process | LIPC |
phosphatidylglycerol acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A |
phosphatidylinositol 3-kinase signaling | biological_process | GATA3, PIK3R1, ERBB3, IGF1, IGF1R, ERBB2, EDN1, C1QBP, TYRO3 |
phosphatidylinositol acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
phosphatidylinositol biosynthetic process | biological_process | FGF2, PIK3R1, PIK3CA, PTEN |
phosphatidylinositol dephosphorylation | biological_process | PTEN |
phosphatidylinositol metabolic process | biological_process | DRD2, CSF1R, PLCB1 |
phosphatidylinositol phosphorylation | biological_process | FGFR1, FGF2, FGFR2, PIK3R1, KIT, ERBB3, PDGFRA, KITLG, PIK3CA, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, NRG1, IRS2 |
phosphatidylinositol-3-phosphate biosynthetic process | biological_process | FGFR1, FGF2, FGFR2, PIK3R1, PIK3CA, FGF1, TLR9, ATM, IRS2 |
phosphatidylinositol-mediated signaling | biological_process | FGFR1, FGF2, FGFR2, PIK3R1, KIT, AKT1, ERBB3, PDGFRA, KITLG, PIK3CA, MTOR, IGF1, EGFR, FGF1, IGF1R, NGF, PDGFA, ERBB2, FYN, EGF, CSF1R, PTEN, NRG1, IRS2, RHOA |
phosphatidylserine acyl-chain remodeling | biological_process | PLA2G4A, PLA2G2A, PLA2G16 |
phosphatidylserine metabolic process | biological_process | LIPC |
phosphoanandamide dephosphorylation | biological_process | PTPN22 |
phospholipase C-activating angiotensin-activated signaling pathway | biological_process | AGTR1 |
phospholipase C-activating dopamine receptor signaling pathway | biological_process | DRD2 |
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway | biological_process | HRH4 |
phospholipase C-activating G-protein coupled receptor signaling pathway | biological_process | F2R, OPRM1, FPR1, AGTR1, CXCR2, TACR1, LHCGR, ESR1, KISS1R |
phospholipase D-activating G-protein coupled receptor signaling pathway | biological_process | EDN1 |
phospholipid biosynthetic process | biological_process | PLA2G16, PEMT |
phospholipid catabolic process | biological_process | PLA2G4A, APOA2 |
phospholipid efflux | biological_process | APOA1, APOA2, APOE |
phospholipid homeostasis | biological_process | CETP, APOA1 |
phospholipid metabolic process | biological_process | PLA2G4A, PLCD1, PLA2G2A, APOA1, RARRES3, GATA6, PLA2G16, PEMT |
phospholipid transport | biological_process | CETP, APOA1, SCARB1 |
phosphorylation | biological_process | GSK3B, FGFR1, SRC, MET, STAT3, MAPK1, FGFR2, KIT, AKT1, ERBB3, NME1, KDR, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, PIK3CA, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, PLK1, PTK2, NTRK2, TYRO3, TEK, PAK1, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2 |
photoperiodism | biological_process | CLOCK |
photoreceptor cell maintenance | biological_process | PROM1 |
phthalate metabolic process | biological_process | SRD5A2, STAR, CYP17A1 |
phytol metabolic process | biological_process | ALDH3A2 |
pigment granule organization | biological_process | BCL2 |
pigmentation | biological_process | BCL2, KIT, DRD2, ATP7A |
pinocytosis | biological_process | AHSG |
pituitary gland development | biological_process | CDH1, BMP4, GATA2, SOX2, SRD5A1 |
placenta blood vessel development | biological_process | NR2F2, ARID1A, SOCS3 |
placenta development | biological_process | PPARG, LEP, HSD17B2, ANG, SOD1, ADA, PTK2, HTRA1, NODAL, DCN |
planar cell polarity pathway involved in axis elongation | biological_process | WNT5A |
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis | biological_process | WNT5A |
planar cell polarity pathway involved in cardiac right atrium morphogenesis | biological_process | WNT5A |
planar cell polarity pathway involved in gastrula mediolateral intercalation | biological_process | WNT5A |
planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation | biological_process | WNT5A |
planar cell polarity pathway involved in neural tube closure | biological_process | WNT5A |
planar cell polarity pathway involved in outflow tract morphogenesis | biological_process | WNT5A |
planar cell polarity pathway involved in pericardium morphogenesis | biological_process | WNT5A |
planar cell polarity pathway involved in ventricular septum morphogenesis | biological_process | WNT5A |
plasma cell differentiation | biological_process | LGALS1 |
plasma lipoprotein particle clearance | biological_process | CD36 |
plasma membrane copper ion transport | biological_process | ATP7A |
plasmacytoid dendritic cell activation | biological_process | HMGB1 |
plasminogen activation | biological_process | FGA, PLAT |
platelet activating factor biosynthetic process | biological_process | PLA2G4A |
platelet activation | biological_process | SRC, CD40LG, F2R, MAPK1, PIK3R1, AKT1, CD40, AXL, SAA1, PIK3CA, FCER1G, ITGB3, FGA, PRKCB, FYN, IL6, RAC1, GAS6, TYRO3, CX3CL1, RHOA |
platelet aggregation | biological_process | PDGFRA, ITGB3, FGA, HSPB1, GAS6, TYRO3, ACTB |
platelet degranulation | biological_process | VEGFA, CLU, CD36, SPARC, HGF, PECAM1, SELP, TIMP3, VEGFC, FN1, IGF1, ITGB3, TGFB1, ACTN4, A2M, SOD1, FGA, SERPINA1, AHSG, APOA1, TIMP1, PDGFA, ABCC4, SERPINE1, THBS1, FIGF, EGF, IGF2, TF, A1BG, PSAP, TGFB2, GAS6, RARRES2 |
platelet dense granule organization | biological_process | F2R |
platelet formation | biological_process | CASP3 |
platelet-derived growth factor receptor signaling pathway | biological_process | SRC, PDGFRA, PLAT, PDGFA, NRP1, PTEN |
platelet-derived growth factor receptor-alpha signaling pathway | biological_process | PDGFRA |
plus-end-directed vesicle transport along microtubule | biological_process | KIFAP3 |
PMA-inducible membrane protein ectodomain proteolysis | biological_process | ADAM17 |
pointed-end actin filament capping | biological_process | TMOD3 |
polarity specification of proximal/distal axis | biological_process | NODAL |
polarized epithelial cell differentiation | biological_process | TP63 |
polyketide metabolic process | biological_process | IL1B |
polysaccharide assembly with MHC class II protein complex | biological_process | HLA-DRB1, HLA-DRA |
polysaccharide digestion | biological_process | AMY2A |
porphyrin-containing compound metabolic process | biological_process | CYP1A2, CYP1A1 |
positive chemotaxis | biological_process | FGF2, VEGFA, MET, BMP4, CCL5, HMGB1, LGALS3, MIF, CCL3, HGF, SAA1, VEGFC, CXCL12, NRP1, CCL16, FIGF, ANGPT1 |
positive regulation by host of viral process | biological_process | CFL1, APOE |
positive regulation by host of viral transcription | biological_process | JUN |
positive regulation of acetylcholine secretion, neurotransmission | biological_process | TACR2 |
positive regulation of acrosome reaction | biological_process | PLCB1 |
positive regulation of actin cytoskeleton reorganization | biological_process | TEK |
positive regulation of actin filament bundle assembly | biological_process | ID1, LIMK1 |
positive regulation of actin filament depolymerization | biological_process | F2RL1 |
positive regulation of actin filament polymerization | biological_process | ALOX15, MTOR, CCL21, ICAM1, RAC1, CCR7, CCL11 |
positive regulation of action potential | biological_process | TACR1 |
positive regulation of activated T cell autonomous cell death | biological_process | LGALS9 |
positive regulation of activated T cell proliferation | biological_process | HMGB1, IGFBP2, IL12B, IGF1, IGF2, IL2RA, IL4, IL18, AGER, IL23A, IL2 |
positive regulation of activation of JAK2 kinase activity | biological_process | CCL5, IL12B, IL23A |
positive regulation of activation of Janus kinase activity | biological_process | IL6R |
positive regulation of activation of membrane attack complex | biological_process | C3 |
positive regulation of activation-induced cell death of T cells | biological_process | TGFB2 |
positive regulation of activin receptor signaling pathway | biological_process | NODAL |
positive regulation of acute inflammatory response | biological_process | IL6ST, IL6, ADAM8 |
positive regulation of adaptive immune response | biological_process | IL6ST, SIRT1 |
positive regulation of adenylate cyclase activity | biological_process | TIMP2 |
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway | biological_process | CRHR1, GPER1 |
positive regulation of adipose tissue development | biological_process | SIRT1 |
positive regulation of aldosterone biosynthetic process | biological_process | BMP6, WNT4 |
positive regulation of aldosterone secretion | biological_process | BMP6 |
positive regulation of alkaline phosphatase activity | biological_process | ITGA2, SMAD3 |
positive regulation of alpha-beta T cell differentiation | biological_process | PNP, ADA, IHH |
positive regulation of alpha-beta T cell proliferation | biological_process | CCR2 |
positive regulation of androgen receptor activity | biological_process | PARK7 |
positive regulation of angiogenesis | biological_process | FGF2, VEGFA, WNT5A, CCL5, CHI3L1, F3, CXCL8, BRCA1, KDR, CXCR3, ENG, GATA2, HGF, FLT1, HMOX1, CMA1, NOS3, ADM, VEGFC, GREM1, FGF1, PRKCB, IL1A, C3, HSPB1, PDCD6, ANGPT2, SERPINE1, THBS1, IL1B, ITGB2, C5, HIF1A, TEK, SIRT1, TWIST1, GATA6, CX3CL1, CYP1B1, NODAL, CCL11 |
positive regulation of anoikis | biological_process | CHEK2 |
positive regulation of antigen processing and presentation of peptide antigen via MHC class I | biological_process | ABCB1 |
positive regulation of antral ovarian follicle growth | biological_process | PTGER4 |
positive regulation of apoptotic cell clearance | biological_process | C4A, CCL2, C3 |
positive regulation of apoptotic DNA fragmentation | biological_process | BAX |
positive regulation of apoptotic process | biological_process | GSK3B, HSPD1, SRC, ITGA6, BCL6, BMP4, PLA2G4A, HMGA2, PPARG, IGF2R, HMGB1, CLU, IGFBP3, MMP9, ANXA5, AKT1, CTNNB1, TNFSF10, NOTCH1, CASP3, RASSF2, FASLG, FAS, IDO1, CTLA4, WT1, PTN, ADM, PTGS2, ITGB1, JUN, TGFB1, ANXA1, SOD1, NGF, TP53, TNF, LATS1, CYR61, KLF11, TLR3, BCL2L11, KALRN, IL1B, LTA, IL6, RAC1, C1QBP, PTEN, BCL2L1, FOXL2, HIF1A, FOXO1, BAX, ESR2, SIRT1, ATM, AGER, GPER1, CDKN2A, CYP1B1, SFRP4, KLRK1, LILRB1 |
positive regulation of apoptotic process by virus | biological_process | CCR2, BCL2L11 |
positive regulation of apoptotic process involved in mammary gland involution | biological_process | VDR, BAX |
positive regulation of apoptotic signaling pathway | biological_process | PTEN, TP63 |
positive regulation of appetite | biological_process | OPRM1, GHRL, NPY |
positive regulation of arachidonic acid secretion | biological_process | MIF |
positive regulation of astrocyte chemotaxis | biological_process | CCR2 |
positive regulation of astrocyte differentiation | biological_process | NOTCH1, IL6ST, LIF, IL1B, ID2 |
positive regulation of ATP biosynthetic process | biological_process | STAT3 |
positive regulation of attachment of spindle microtubules to kinetochore | biological_process | CCNB1 |
positive regulation of autophagy | biological_process | IFNG, HIF1A, FOXO1, AGER, PIM2, DCN |
positive regulation of axon extension | biological_process | GSK3B, L1CAM, FN1, NRG1, LIMK1 |
positive regulation of axon extension involved in axon guidance | biological_process | VEGFA, CXCL12, NRP1 |
positive regulation of axon regeneration | biological_process | BRAF, CNTF |
positive regulation of axonogenesis | biological_process | BRAF, NGF, NTRK2, RHOA |
positive regulation of B cell activation | biological_process | IL4, IL6, NOD2 |
positive regulation of B cell apoptotic process | biological_process | IL10, BAX |
positive regulation of B cell differentiation | biological_process | MMP14, PRDM1 |
positive regulation of B cell proliferation | biological_process | BCL2, BCL6, MIF, CDKN1A, CD40, IL13, TLR4, ADA, CD74, IL4, IL5, TNFSF13B, IRS2, IL2 |
positive regulation of B cell receptor signaling pathway | biological_process | PRKCB |
positive regulation of behavioral fear response | biological_process | GJA1, CRH, UCN |
positive regulation of beta-amyloid formation | biological_process | CLU, APOE |
positive regulation of binding | biological_process | PON1, ENO1, ANXA2 |
positive regulation of blood circulation | biological_process | PTGER3 |
positive regulation of blood coagulation | biological_process | F2R, CD36, SERPINE1, THBS1, HPSE, NFE2L2 |
positive regulation of blood microparticle formation | biological_process | CD36, TNF |
positive regulation of blood pressure | biological_process | TACR1, OXTR, ADIPOQ, ID2, CRHR2 |
positive regulation of blood vessel endothelial cell migration | biological_process | FGF2, VEGFA, AKT1, VEGFC, TGFB1, HSPB1, THBS1, ANGPT1 |
positive regulation of BMP signaling pathway | biological_process | BMP4, NOTCH1, ENG, CYR61, HES5, SMAD2, SMAD4, GATA6 |
positive regulation of bone mineralization | biological_process | BMP4, PLA2G4A, BMP6, TGFB1, BMPR1B, SMAD3, WNT4 |
positive regulation of bone mineralization involved in bone maturation | biological_process | LTF |
positive regulation of bone resorption | biological_process | PTGER4, SPP1, CA2, FSHB, ADAM8 |
positive regulation of brain-derived neurotrophic factor receptor signaling pathway | biological_process | BDNF |
positive regulation of branching involved in lung morphogenesis | biological_process | BMP4, CTNNB1 |
positive regulation of branching involved in ureteric bud morphogenesis | biological_process | VEGFA, AGTR2, GREM1, TGFB1, PAX2 |
positive regulation of brown fat cell differentiation | biological_process | PTGS2 |
positive regulation of calcidiol 1-monooxygenase activity | biological_process | IFNG, TNF, IL1B |
positive regulation of calcineurin-NFAT signaling cascade | biological_process | ERBB3, IGF1, NRG1 |
positive regulation of calcitonin secretion | biological_process | PTGER4 |
positive regulation of calcium ion import | biological_process | LGALS3, CCL3, CCL2, CXCL12, CRH, UCN, STC1 |
positive regulation of calcium ion transport | biological_process | F2R, CCL5, CCL3, CCR1, EDNRA, LPAR3 |
positive regulation of calcium ion transport into cytosol | biological_process | BMP4, CD4, BAX, P2RX3 |
positive regulation of calcium-dependent cell-cell adhesion | biological_process | KIFAP3 |
positive regulation of calcium-independent cell-cell adhesion | biological_process | CX3CL1 |
positive regulation of calcium-mediated signaling | biological_process | CCL3, CD4, ADA, P2RX3 |
positive regulation of cAMP biosynthetic process | biological_process | PTGER4, ADM, PTGER3, GHRH, CRH, GPER1, UCN, CRHR2 |
positive regulation of cAMP metabolic process | biological_process | CXCR3, CXCL10, CRHR2 |
positive regulation of cAMP-dependent protein kinase activity | biological_process | ADIPOQ, SIRT1 |
positive regulation of cAMP-mediated signaling | biological_process | OPRM1, CXCR3, LHCGR, CXCL10 |
positive regulation of canonical Wnt signaling pathway | biological_process | SRC, YAP1, FGFR2, NFKB1, WNT2, PSMD9, LGR5, WNT7A, PSMD10, WNT1, DLX5, WNT4, SFRP4 |
positive regulation of cardiac muscle cell differentiation | biological_process | GREM1, TGFB1, NRG1 |
positive regulation of cardiac muscle cell proliferation | biological_process | FGFR1, FGF2, FGFR2, CCNB1, WNT2, NOTCH1, NRG1, GATA6 |
positive regulation of cardiac muscle contraction | biological_process | HSP90AA1, UCN |
positive regulation of cardiac muscle fiber development | biological_process | BMP4 |
positive regulation of cardiac muscle hypertrophy | biological_process | IL6ST, IGF1, EDN1 |
positive regulation of cardiac vascular smooth muscle cell differentiation | biological_process | GPER1 |
positive regulation of cardioblast differentiation | biological_process | TGFB2, GATA6 |
positive regulation of cardiolipin metabolic process | biological_process | STOML2 |
positive regulation of cartilage development | biological_process | BMP4, WNT5A, BMPR1B, CYR61 |
positive regulation of catagen | biological_process | TGFB2 |
positive regulation of catalytic activity | biological_process | BCL2, IGFBP3, CASP3, CXCL1, SOD1, APOA2, IGF2, PSAP, ATP7A, DNMT3L, MMP24 |
positive regulation of catenin import into nucleus | biological_process | EGFR, EGF, POU5F1 |
positive regulation of CD24 biosynthetic process | biological_process | PLCB1 |
positive regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | CD83 |
positive regulation of CD4-positive, alpha-beta T cell proliferation | biological_process | LGALS9 |
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | biological_process | FOXP3 |
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response | biological_process | IFNG, LGALS9 |
positive regulation of CD8-positive, alpha-beta T cell extravasation | biological_process | CCR2 |
positive regulation of CD8-positive, alpha-beta T cell proliferation | biological_process | HLA-E |
positive regulation of cell adhesion | biological_process | SRC, VEGFA, CCL5, IL12B, PTGER4, ITGA2, SAA1, CCL2, SELP, IL12A, CXCL12, ITGAV, IFNG, TNF, ERBB2, C1QBP, NRG1, ADAM8, CX3CL1, ANGPT1, CCR7 |
positive regulation of cell adhesion mediated by integrin | biological_process | CCL21, TGFB2 |
positive regulation of cell adhesion molecule production | biological_process | IL1B |
positive regulation of cell communication by chemical coupling | biological_process | GJA1 |
positive regulation of cell cycle | biological_process | FGFR1, CCND1, FGFR2, CCNB1, SLC6A4, CDKN1B, BCL2L11, TGFB2 |
positive regulation of cell cycle arrest | biological_process | HMGA2, BRCA1, TGFB1, TP53, ID2, CDKN2A, GATA6 |
positive regulation of cell cycle G1/S phase transition | biological_process | TP63 |
positive regulation of cell death | biological_process | BMP4, CDKN1B, CDKN1A, FAS, MTOR, PTGS2, AKR1C3, BCL2L11, IL1B, HP, CRH, DNMT3A, NOD1 |
positive regulation of cell development | biological_process | HOXA11 |
positive regulation of cell differentiation | biological_process | GATA3, BMP4, CLU, AR, SOX2, JUN, BMPR1B, CYR61, SOCS3 |
positive regulation of cell division | biological_process | FGF2, VEGFA, FGFR2, PTN, MDK, VEGFC, FGF1, TGFB1, IL1A, PDGFA, FIGF, IL1B, IGF2, CAT, TGFB2, YBX1, PROK1 |
positive regulation of cell fate specification | biological_process | FGF2 |
positive regulation of cell growth | biological_process | BCL2, AKT1, IGFBP1, IL9, MMP14, IGF1, EGFR, ERBB2, SGK1, PSMD10, CDC42, TGFB2, NRG1, ADAM17, UCN, IL2, CXCL16 |
positive regulation of cell growth involved in cardiac muscle cell development | biological_process | MTOR |
positive regulation of cell migration | biological_process | VEGFA, BMP4, F2R, CCL5, MAPK1, PIK3R1, F3, KIT, CCL3, NOTCH1, KDR, CSF1, CCR1, PDGFRA, HGF, FLT1, TDGF1, MMP14, COL18A1, CXCL12, FN1, INSR, IGF1, ITGB1, EGFR, FGF1, ITGAV, TGFB1, ACTN4, IGF1R, CXCL10, PDGFA, CYR61, SNAI1, THBS1, PLAU, CGA, FSHB, EDN1, CSF1R, PTK2, SMAD3, PAK1, F2RL1, AIF1, ADAM17, AGER, GPER1, IRS2, CCL7, CX3CL1, SEMA3C, CXCL16, CCL11 |
positive regulation of cell migration involved in sprouting angiogenesis | biological_process | VEGFA, PTGS2, CCR2 |
positive regulation of cell motility | biological_process | EPCAM, CCL21, CLDN7, CSF1R, CCL19, TWIST1, CCR7 |
positive regulation of cell projection organization | biological_process | ITGA2 |
positive regulation of cell proliferation | biological_process | BCL2, FGFR1, YAP1, FGF2, CCND1, VEGFA, BMP4, PLA2G4A, F2R, WNT5A, MAPK1, FGFR2, CLU, KIT, LEP, SHC1, CTNNB1, EPCAM, PTGER4, AR, WNT2, CDKN1B, NOTCH1, KDR, FASLG, CSF1, FLT4, CXCR3, PDGFRA, AGTR2, IL6R, IL6ST, EDNRA, HGF, FLT1, STS, CNTF, CXCR2, KITLG, TDGF1, IL15, LIF, LIFR, IL9, IL11, PTN, TNC, FLT3, ADM, PTGS2, VEGFC, COL18A1, AKR1C3, CXCL5, PTGFR, CXCL12, AKR1C2, FN1, INSR, IGF1, GREM1, ITGB1, EGFR, JUN, FGF1, ITGAV, IFNG, TGFB1, IGF1R, TIMP1, MYC, CXCL10, PDGFA, BIRC5, WNT7A, FIGF, GDF9, CLDN7, EGF, PLAU, KRAS, CGA, FSHB, GHRH, IGF2, CSF2, WNT1, IL4, IL5, IL6, EDN1, CRH, CSF1R, PTEN, TGFB2, PTK2, HDAC2, RELA, NRG1, BCL2L1, NTRK2, HIF1A, HES5, S100A13, HDAC1, TNFSF13B, MST1R, SIRT1, ADAM17, GPER1, IL24, PAX2, IRS2, PROK1, IL2, NODAL, CLEC11A, TET1 |
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway | biological_process | VEGFA, PDGFRA |
positive regulation of cell proliferation in bone marrow | biological_process | IL6 |
positive regulation of cell proliferation involved in heart valve morphogenesis | biological_process | SMAD4 |
positive regulation of cell size | biological_process | HSP90AA1, EDN1, HIF1A |
positive regulation of cell-cell adhesion | biological_process | ITGA6, WNT5A, CCL2, SOX2, CCR2, FSTL3, SMAD7, NODAL |
positive regulation of cell-cell adhesion mediated by cadherin | biological_process | WNT5A |
positive regulation of cell-cell adhesion mediated by integrin | biological_process | CCL5, CXCL13 |
positive regulation of cell-matrix adhesion | biological_process | GSK3B, CD36, CSF1, VEGFC, CCL25, CCL21, CCR7 |
positive regulation of cell-substrate adhesion | biological_process | ITGA3, ALOX15, PTN, ITGB1, CYR61, AGR2, RAC1, SPOCK2, SMOC2 |
positive regulation of cellular biosynthetic process | biological_process | CCL5 |
positive regulation of cellular component movement | biological_process | VEGFA, BCL6, STMN1, ACTN4, ADAM17 |
positive regulation of cellular extravasation | biological_process | CCL2, ICAM1, ADAM8 |
positive regulation of cellular metabolic process | biological_process | ACLY |
positive regulation of cellular pH reduction | biological_process | CA2 |
positive regulation of cellular protein metabolic process | biological_process | INHBA, AKT1, CSF1, AGTR1, TGFB1, ADIPOQ |
positive regulation of cellular response to X-ray | biological_process | HMGA2 |
positive regulation of cellular senescence | biological_process | HMGA2, HMGA1, CDKN2A, SIRT1 |
positive regulation of ceramide biosynthetic process | biological_process | TNFRSF1A, TNF, CYR61, SMPD3 |
positive regulation of cerebellar granule cell precursor proliferation | biological_process | EGF |
positive regulation of cGMP biosynthetic process | biological_process | APOE |
positive regulation of cGMP metabolic process | biological_process | WNT5A |
positive regulation of chemokine (C-C motif) ligand 2 secretion | biological_process | POSTN |
positive regulation of chemokine (C-X-C motif) ligand 2 production | biological_process | MIF, TNF, CD74 |
positive regulation of chemokine biosynthetic process | biological_process | WNT5A, HMOX1, IFNG, TNF, TLR3, IL1B, IL4 |
positive regulation of chemokine production | biological_process | IL6R, TNF, TLR2, TLR4, TLR3, IL6, HIF1A, TLR9, ADAM17 |
positive regulation of chemokine secretion | biological_process | IL33, C5, CSF1R, IL1RL1 |
positive regulation of chemokine-mediated signaling pathway | biological_process | EDN1, HIF1A |
positive regulation of chemokinesis | biological_process | PTGER4 |
positive regulation of chemotaxis | biological_process | CXCR3, FN1, TGFB1, CCL21, THBS1, F2RL1, CCL19, RARRES2 |
positive regulation of cholangiocyte proliferation | biological_process | MTOR |
positive regulation of cholesterol biosynthetic process | biological_process | FGF1 |
positive regulation of cholesterol efflux | biological_process | PON1, APOE, ADIPOQ, SIRT1 |
positive regulation of cholesterol esterification | biological_process | AGTR1, APOA1, APOA2, APOE |
positive regulation of cholesterol storage | biological_process | CD36, SCARB1 |
positive regulation of chondrocyte differentiation | biological_process | BMP6, HOXA11, BMPR1B, SMAD3, RELA, IHH |
positive regulation of chondrocyte proliferation | biological_process | LTF |
positive regulation of chromatin binding | biological_process | KAT2B |
positive regulation of chromatin silencing | biological_process | SIRT1 |
positive regulation of chromatin-mediated maintenance of transcription | biological_process | CTNNB1 |
positive regulation of chronic inflammatory response | biological_process | IDO1 |
positive regulation of chronic inflammatory response to antigenic stimulus | biological_process | TNF, LTA |
positive regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | PTGER4, PTGER3, GHRL |
positive regulation of circadian sleep/wake cycle, REM sleep | biological_process | GHRH |
positive regulation of circadian sleep/wake cycle, wakefulness | biological_process | CRH |
positive regulation of collagen binding | biological_process | ITGA2 |
positive regulation of collagen biosynthetic process | biological_process | BMP4, F2R, ITGA2, CCL2, TGFB1, HDAC2, UCN, WNT4 |
positive regulation of collagen metabolic process | biological_process | RETN |
positive regulation of collateral sprouting | biological_process | BDNF, LPAR3 |
positive regulation of colon smooth muscle contraction | biological_process | PTGER3 |
positive regulation of connective tissue growth factor production | biological_process | IL13 |
positive regulation of corticosterone secretion | biological_process | CRH |
positive regulation of corticotropin secretion | biological_process | LIF, CRH, GHRL, UCN |
positive regulation of cortisol biosynthetic process | biological_process | WNT4 |
positive regulation of cortisol secretion | biological_process | CRH, GHRL |
positive regulation of CREB transcription factor activity | biological_process | VEGFA |
positive regulation of cyclic nucleotide-gated ion channel activity | biological_process | CFTR |
positive regulation of cyclin-dependent protein kinase activity | biological_process | CDKN1A |
positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological_process | SRC, CCND1, CDKN1B, PSMD10 |
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological_process | AKT1, EGFR, ADAM17 |
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | F2R, HMGB1, TNFSF10, FAS, TNF, MYC, PDCD6, CYR61, BCL2L11, FOXL2, SIRT1, NOD1, GPER1, DAPK1, NODAL |
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological_process | LGALS9 |
positive regulation of cytokine activity | biological_process | NRP1 |
positive regulation of cytokine production | biological_process | GATA3, WNT5A, LEP, SOD1, TNF, TLR3 |
positive regulation of cytokine production involved in inflammatory response | biological_process | NOD2, IL17A, IL17F |
positive regulation of cytokine secretion | biological_process | SRC, IL10, MIF, PTGER4, CASP1, AGTR2, SAA1, IL1A, TNF, CADM1 |
positive regulation of cytokine secretion involved in immune response | biological_process | WNT5A, F2RL1 |
positive regulation of cytokine-mediated signaling pathway | biological_process | AXL, CD74, GAS6 |
positive regulation of cytokinesis | biological_process | DRD2, SSTR5, CDC42, RHOA |
positive regulation of cytolysis | biological_process | LILRB1 |
positive regulation of cytosolic calcium ion concentration | biological_process | F2R, HMGB1, GJA1, CD36, OPRM1, CCR1, CCR5, CXCR3, PDGFRA, AGTR1, EDNRA, GATA2, SAA1, TACR1, OXTR, ADM, CCR2, PTGER3, CCR9, ESR1, CXCL13, IL1B, EDN1, CXCR4, F2RL1, GHRL, GPER1, IL2, KISS1, HRH4, LPAR3, CCR7, CCR8 |
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | biological_process | F2R, DRD2, AGTR1, EDNRA, EDN1, KISS1, LPAR3 |
positive regulation of defense response to virus by host | biological_process | IL12B, ANXA5, MSTN, CLDN7, IL4, IL23A, LILRB1 |
positive regulation of dendrite development | biological_process | EZH2 |
positive regulation of dendrite morphogenesis | biological_process | SGK1 |
positive regulation of dendritic cell antigen processing and presentation | biological_process | CCL21, CD74, NOD2, CCL19, NOD1, CCR7 |
positive regulation of dendritic cell apoptotic process | biological_process | LGALS9 |
positive regulation of dendritic cell chemotaxis | biological_process | IL12A, LGALS9, C1QBP, GAS6, CCR7 |
positive regulation of dendritic cell dendrite assembly | biological_process | CCL19 |
positive regulation of dendritic cell differentiation | biological_process | HMGB1, LGALS3, LGALS1, LGALS9, AGER |
positive regulation of dendritic spine development | biological_process | MTOR, APOE, NRG1, IL2 |
positive regulation of dendritic spine maintenance | biological_process | APOE |
positive regulation of deoxyribonuclease activity | biological_process | PCNA |
positive regulation of dermatome development | biological_process | WNT1, WNT4 |
positive regulation of determination of dorsal identity | biological_process | CTNNB1 |
positive regulation of developmental growth | biological_process | LEP, INSR, C3, AGR2, PLCB1 |
positive regulation of developmental pigmentation | biological_process | BCL2, BAX |
positive regulation of digestive system process | biological_process | CRH |
positive regulation of dipeptide transmembrane transport | biological_process | CA2 |
positive regulation of DNA binding | biological_process | TXN, HMGB1, MMP9, NME1, ITGA2, IGF1, EGF, PLAUR |
positive regulation of DNA biosynthetic process | biological_process | GSK3B, SRC, HGF, MYC |
positive regulation of DNA damage response, signal transduction by p53 class mediator | biological_process | ATM, CDKN2A |
positive regulation of DNA ligation | biological_process | HMGB1 |
positive regulation of DNA repair | biological_process | H2AFX, PCNA, APEX1, BRCA1, EGFR, SIRT1 |
positive regulation of DNA replication | biological_process | PCNA, SHC1, PDGFRA, KITLG, INSR, IGF1, EGFR, JUN, IGF1R, PDGFA, CSF2, IL6, CDC42, RAC1, UCN |
positive regulation of DNA-dependent DNA replication | biological_process | BMP4, BMP6 |
positive regulation of DNA-templated transcription, initiation | biological_process | CTNNB1, JUN, TWIST1 |
positive regulation of dopamine biosynthetic process | biological_process | PARK7 |
positive regulation of dopamine secretion | biological_process | CXCL12 |
positive regulation of dopamine uptake involved in synaptic transmission | biological_process | DRD2 |
positive regulation of eating behavior | biological_process | MTOR |
positive regulation of embryonic development | biological_process | PLCB1 |
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation | biological_process | TWIST1 |
positive regulation of endocytosis | biological_process | WNT5A, ITGB1, CCL19 |
positive regulation of endodeoxyribonuclease activity | biological_process | AKT1 |
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological_process | BCL2L11, SIRT1 |
positive regulation of endoplasmic reticulum unfolded protein response | biological_process | PIK3R1, BAX |
positive regulation of endothelial cell apoptotic process | biological_process | BMP4, CD40LG, FASLG, CD40, COL18A1, AKR1C3, THBS1, AGER, GPER1 |
positive regulation of endothelial cell chemotaxis | biological_process | MET, HSPB1 |
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway | biological_process | VEGFA, KDR, HSPB1 |
positive regulation of endothelial cell chemotaxis to fibroblast growth factor | biological_process | FGFR1, FGF2 |
positive regulation of endothelial cell differentiation | biological_process | BMP4, CTNNB1, NOTCH1, BMP6 |
positive regulation of endothelial cell migration | biological_process | GATA3, VEGFA, BMP4, WNT5A, KDR, FLT4, SPARC, TDGF1, ITGB3, FGF1, PDCD6, WNT7A, NRP1, THBS1, NRP2, EDN1, FOXP1, TEK, SCARB1, ANGPT1 |
positive regulation of endothelial cell proliferation | biological_process | FGF2, VEGFA, BMP4, WNT5A, F3, AKT1, WNT2, KDR, FLT4, CCL2, BMP6, ARNT, MTOR, CXCL12, ITGB3, JUN, ANG, PDCD6, NRP1, NRP2, HIF1A, TEK, SIRT1, CCL11 |
positive regulation of energy homeostasis | biological_process | GHRL |
positive regulation of eosinophil chemotaxis | biological_process | IL4 |
positive regulation of eosinophil degranulation | biological_process | F2RL1 |
positive regulation of eosinophil differentiation | biological_process | IL5 |
positive regulation of eosinophil migration | biological_process | ADAM8 |
positive regulation of epidermal cell differentiation | biological_process | BMP4, SFRP4 |
positive regulation of epidermal growth factor receptor signaling pathway | biological_process | MMP9, AKT1, FASLG, ESR1, AGR2, PLAUR, ESR2, GPER1 |
positive regulation of epidermal growth factor-activated receptor activity | biological_process | EGF, ADAM17 |
positive regulation of epithelial cell apoptotic process | biological_process | TIA1 |
positive regulation of epithelial cell differentiation | biological_process | CTNNB1 |
positive regulation of epithelial cell migration | biological_process | SRC, ITGA3, ITGA2, TACR1, JUN, IFNG, TGFB2, HIF1A |
positive regulation of epithelial cell proliferation | biological_process | VEGFA, BMP4, WNT5A, CCL5, FGFR2, NOTCH1, NME1, ID1, TACR1, BMP6, VEGFC, MMP12, ESR1, IGF1, EGFR, FGF1, TGFB1, MYC, ERBB2, IL6, NOD2, TWIST1, PAX2, DLX5, IHH, HTRA1, NODAL, LAMC1 |
positive regulation of epithelial cell proliferation involved in lung morphogenesis | biological_process | FGFR2, WNT2, CDC42 |
positive regulation of epithelial cell proliferation involved in prostate gland development | biological_process | CTNNB1 |
positive regulation of epithelial cell proliferation involved in wound healing | biological_process | MMP12, WNT7A |
positive regulation of epithelial to mesenchymal transition | biological_process | CTNNB1, NOTCH1, TGFB1, SNAI1, TGFB1I1, TGFB2, HDAC2, SMAD3, SMAD2, EZH2, SMAD4, AGER, TWIST1, OLFM1 |
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | TGFB2 |
positive regulation of ER-associated ubiquitin-dependent protein catabolic process | biological_process | NFE2L2 |
positive regulation of ERK1 and ERK2 cascade | biological_process | SRC, FGF2, VEGFA, FSHR, BMP4, F2R, CCL5, FGFR2, HMGB1, CD36, ALOX15, CHI3L1, OPRM1, MIF, CCL3, DRD2, KDR, CCR1, FLT4, BRAF, PDGFRA, EDNRA, CD44, CCL2, PLA2G2A, ESR1, EGFR, JUN, FGF1, FGA, TNF, PDGFA, C3, LGALS9, TLR4, CCL25, CCL21, CCL22, NRP1, CCL16, SPRY2, IL1B, ICAM1, CD74, IL6, CSF1R, PTEN, GAS6, TEK, F2RL1, NOD2, ESR2, CCL19, NOD1, PTPN22, GPER1, CCL7, CX3CL1, ANGPT1, CCL17, NODAL, CCR7, CCL11 |
positive regulation of erythrocyte aggregation | biological_process | LGALS1 |
positive regulation of erythrocyte differentiation | biological_process | INHBA, GATA2, ARNT, HIF1A, ID2 |
positive regulation of establishment of endothelial barrier | biological_process | CLDN5 |
positive regulation of establishment of protein localization to plasma membrane | biological_process | ITGA3, PIK3R1, AKT1, ITGB1, IFNG, AGR2, GPER1 |
positive regulation of excitatory postsynaptic potential | biological_process | GSK3B, WNT7A, PTEN |
positive regulation of excitatory synapse assembly | biological_process | WNT7A |
positive regulation of execution phase of apoptosis | biological_process | CXCR3, TP53 |
positive regulation of exit from mitosis | biological_process | TGFB1, BIRC5 |
positive regulation of exocytosis | biological_process | CFTR, FGA |
positive regulation of exosomal secretion | biological_process | SDC4, SDC1, IFNG, SMPD3 |
positive regulation of extracellular exosome assembly | biological_process | SDC4, SDC1 |
positive regulation of extracellular matrix assembly | biological_process | TGFB1, SMAD3 |
positive regulation of extracellular matrix constituent secretion | biological_process | CPB2 |
positive regulation of extracellular matrix disassembly | biological_process | TGFB2 |
positive regulation of extrinsic apoptotic signaling pathway | biological_process | TNFSF10, AGTR2, G0S2, FAS, GPER1 |
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological_process | INHBA, CTNNA1, FAS, TGFB2, BAX |
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological_process | BMPR1B, THBS1 |
positive regulation of fat cell apoptotic process | biological_process | LEP |
positive regulation of fat cell differentiation | biological_process | PPARG, AKT1, IGF1, RARRES2, ID2, SULT1E1 |
positive regulation of fatty acid beta-oxidation | biological_process | PPARA, TWIST1, IRS2 |
positive regulation of fatty acid biosynthetic process | biological_process | APOA1 |
positive regulation of fatty acid metabolic process | biological_process | ADIPOQ |
positive regulation of fatty acid oxidation | biological_process | PPARG, PPARA |
positive regulation of fever generation | biological_process | PLA2G4A, CCL5, PTGS2, CCR2, PTGER3, TNF, IL1B |
positive regulation of fibroblast apoptotic process | biological_process | BCL2L11, TP63 |
positive regulation of fibroblast growth factor production | biological_process | PTGS2 |
positive regulation of fibroblast growth factor receptor signaling pathway | biological_process | CTNNB1 |
positive regulation of fibroblast migration | biological_process | AKT1, TGFB1, THBS1, AGER |
positive regulation of fibroblast proliferation | biological_process | WNT5A, FBLN1, MIF, CCNB1, WNT2, CDKN1A, PDGFRA, FN1, ESR1, IGF1, EGFR, JUN, TGFB1, S100A6, MYC, PDGFA, ANXA2, CD74, WNT1, GAS6, AGER |
positive regulation of fibronectin-dependent thymocyte migration | biological_process | ADAM8 |
positive regulation of filopodium assembly | biological_process | CCL21, CCR7 |
positive regulation of focal adhesion assembly | biological_process | VEGFA, KDR, SDC4, RAC1, SMAD3, TEK, WNT4 |
positive regulation of follicle-stimulating hormone secretion | biological_process | INHBA, LEP, INHA, FOXL2, SMAD4 |
positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity | biological_process | IFNG |
positive regulation of fructose 1,6-bisphosphate metabolic process | biological_process | IFNG |
positive regulation of G-protein coupled receptor protein signaling pathway | biological_process | DRD2, C3, GPER1 |
positive regulation of G0 to G1 transition | biological_process | SOX15 |
positive regulation of G1/S transition of mitotic cell cycle | biological_process | APEX1, ANXA1, CYP1A1, PLCB1, AIF1 |
positive regulation of G2/M transition of mitotic cell cycle | biological_process | CCND1 |
positive regulation of gamma-delta T cell activation | biological_process | NOD2 |
positive regulation of gamma-delta T cell activation involved in immune response | biological_process | LILRB1 |
positive regulation of gastric mucosal blood circulation | biological_process | PTGER3 |
positive regulation of gene expression | biological_process | SRC, GATA3, INHBA, VEGFA, STAT3, BMP4, DNMT1, HMGA2, ITGA3, CCL5, FBLN1, GJA1, KIT, VIM, CTNNB1, BRCA1, PTGER4, CCL3, SLC6A4, NFKB1, AR, ID1, CSF1, VDR, BRAF, CNTF, LIF, HNF1B, CDH3, TNC, MTOR, CCR2, PTGFR, PTGER3, STAR, FN1, IFNG, TGFB1, IL1A, NGF, TP53, TNF, LGALS9, TLR2, TLR4, CRP, WNT7A, TLR3, SPRY2, PRDM1, IL1B, IL33, AGR2, KRAS, AMH, CSF2, IL6, CRH, CDC42, TGFB2, SMAD3, PARK7, NTRK2, HIF1A, GAS6, SMAD2, TLR9, NFE2L2, IL18, FOXP3, ID2, PTPN22, AGER, TWIST1, GPER1, DNMT3B, NR0B2, UCN, DLL4, CRHR2, SFRP4, OLFM1, MAF, LILRB1, PIAS3 |
positive regulation of gene expression, epigenetic | biological_process | ACTB, KAT2B, HIST2H3A |
positive regulation of gene silencing by miRNA | biological_process | STAT3 |
positive regulation of germinal center formation | biological_process | ADA |
positive regulation of glial cell differentiation | biological_process | NOTCH1, IL1B |
positive regulation of glial cell proliferation | biological_process | MTOR, LTA |
positive regulation of glial cell-derived neurotrophic factor secretion | biological_process | DRD2 |
positive regulation of glomerular filtration | biological_process | GJA1, GAS6, F2RL1 |
positive regulation of glomerular metanephric mesangial cell proliferation | biological_process | EGR1 |
positive regulation of gluconeogenesis | biological_process | FOXO1, PPARA |
positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter | biological_process | KAT2B |
positive regulation of glucose import | biological_process | PIK3R1, AKT1, INSR, IGF1, ADIPOQ, NFE2L2, IRS2, ADIPOR2 |
positive regulation of glucose import in response to insulin stimulus | biological_process | PIK3R1, RARRES2 |
positive regulation of glucose metabolic process | biological_process | SRC, AKT1, IRS2 |
positive regulation of glucose transport | biological_process | C3 |
positive regulation of glutamate secretion | biological_process | DPYSL2 |
positive regulation of glutathione biosynthetic process | biological_process | NFE2L2 |
positive regulation of glycogen (starch) synthase activity | biological_process | IGF2, ADIPOQ |
positive regulation of glycogen biosynthetic process | biological_process | AKT1, INSR, IGF1, IGF2, IRS2 |
positive regulation of glycogen catabolic process | biological_process | HMGB1 |
positive regulation of glycolytic process | biological_process | ARNT, INSR, IGF1, HIF1A |
positive regulation of glycoprotein biosynthetic process | biological_process | INSR, IGF1, CCL21, CCL19 |
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation | biological_process | CCR7 |
positive regulation of granulocyte macrophage colony-stimulating factor production | biological_process | IL12B, PAEP, IL1B, TLR9, IL18, IL23A |
positive regulation of granulosa cell proliferation | biological_process | MTOR |
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation | biological_process | STAT3 |
positive regulation of growth hormone receptor signaling pathway | biological_process | GHRL |
positive regulation of growth hormone secretion | biological_process | DRD2, GHRH, GHRL, KISS1 |
positive regulation of GTP binding | biological_process | TGFB2 |
positive regulation of GTPase activity | biological_process | GSK3B, FGFR1, ITGA6, FGF2, WNT5A, CCL5, FGFR2, KIT, SHC1, CCL3, ERBB3, CSF2RB, CD40, PDGFRA, JAK1, KITLG, CCL2, NCAM1, IL2RB, ITGB1, EGFR, JUN, FGF1, A2M, PDGFA, ERBB2, CCL25, FYN, CCL22, CCL16, KALRN, EGF, IL2RA, ICAM1, CSF2, IL5, PTK2, NRG1, PLCB1, TEK, CCL19, ERRFI1, EZH2, IRS2, CCL7, CX3CL1, WNT4, IL2, ANGPT1, CCL17, CCL11 |
positive regulation of guanylate cyclase activity | biological_process | NOS2, NOS3 |
positive regulation of hair cycle | biological_process | TERT |
positive regulation of hair follicle cell proliferation | biological_process | CDC42 |
positive regulation of hair follicle development | biological_process | FST, TNF, HPSE |
positive regulation of heart contraction | biological_process | TGFB2 |
positive regulation of heart growth | biological_process | WT1 |
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway | biological_process | DKK1 |
positive regulation of heart rate | biological_process | ADM, ADA, EDN1, CRHR2 |
positive regulation of helicase activity | biological_process | MSH2, MSH6 |
positive regulation of hematopoietic stem cell migration | biological_process | CCR2 |
positive regulation of hematopoietic stem cell proliferation | biological_process | KITLG |
positive regulation of heparan sulfate proteoglycan biosynthetic process | biological_process | CTNNB1 |
positive regulation of hepatic stellate cell activation | biological_process | LEP |
positive regulation of hepatocyte differentiation | biological_process | BMP4 |
positive regulation of hepatocyte proliferation | biological_process | PTN |
positive regulation of heterotypic cell-cell adhesion | biological_process | ALOX15, CD44, FGA, TNF, IL1B |
positive regulation of histone acetylation | biological_process | BRCA1, TGFB1, IL1B, FOXP3 |
positive regulation of histone deacetylase activity | biological_process | VEGFA |
positive regulation of histone deacetylation | biological_process | BCL6, TGFB1, TP53 |
positive regulation of histone H3-K14 acetylation | biological_process | GATA3, KAT2B |
positive regulation of histone H3-K27 acetylation | biological_process | LIF |
positive regulation of histone H3-K4 methylation | biological_process | DNMT1, CTNNB1, BRCA1, SMAD4, DNMT3B |
positive regulation of histone H3-K9 acetylation | biological_process | GATA3, BRCA1, KAT2B, SMAD4 |
positive regulation of histone H3-K9 methylation | biological_process | BRCA1, SIRT1 |
positive regulation of histone H4 acetylation | biological_process | MUC1 |
positive regulation of histone H4-K16 acetylation | biological_process | BRCA1 |
positive regulation of histone H4-K20 methylation | biological_process | BRCA1 |
positive regulation of histone methylation | biological_process | TET1 |
positive regulation of histone phosphorylation | biological_process | CCNB1, IL1B, ATM |
positive regulation of homocysteine metabolic process | biological_process | COMT |
positive regulation of homotypic cell-cell adhesion | biological_process | CCL5 |
positive regulation of hormone biosynthetic process | biological_process | ARNT, HIF1A |
positive regulation of hormone secretion | biological_process | TACR1, GHRH, EDN1, KISS1R |
positive regulation of humoral immune response | biological_process | CCR7 |
positive regulation of humoral immune response mediated by circulating immunoglobulin | biological_process | TNF, LTA, HPX, FCER2 |
positive regulation of hyaluronan biosynthetic process | biological_process | PTGER4, NFKB1, EGF |
positive regulation of hydrolase activity | biological_process | APOA1 |
positive regulation of hypersensitivity | biological_process | CCR7 |
positive regulation of I-kappaB kinase/NF-kappaB signaling | biological_process | F2R, TNFRSF1A, GJA1, CD36, CTNNB1, CASP1, TNFSF10, FASLG, CD40, LGALS1, HMOX1, RHOC, MAP3K7, PRKCB, IL1A, LTF, TNF, LGALS9, TLR4, FYN, CCDC22, CCL21, TLR3, IL1B, RELA, S100A13, F2RL1, ADIPOQ, TLR9, NOD2, CCL19, NOD1, PIM2, CCR7, RHOA |
positive regulation of immature T cell proliferation in thymus | biological_process | IL1B, FOXP3 |
positive regulation of immune complex clearance by monocytes and macrophages | biological_process | CCL2, CCR2 |
positive regulation of immune response | biological_process | IL15, FCER1G, CTSG, TGFB2 |
positive regulation of immunoglobulin production | biological_process | IL13, HPX, IL4 |
positive regulation of immunoglobulin secretion | biological_process | HLA-E, IL33, IL5, IL6, IL2 |
positive regulation of immunological synapse formation | biological_process | CCR7 |
positive regulation of inflammatory response | biological_process | PLA2G4A, WNT5A, TNFRSF1A, CCL5, IL12B, PTGER4, CCL3, AGTR1, EDNRA, ITGA2, CCL2, PLA2G2A, IL15, CCR2, CLOCK, TLR2, TLR4, TLR3, CCL16, SERPINE1, IL33, TLR9, IL18, AGER, ADAM8, IL1RL1, IL23A, CCL7, CX3CL1, IL2, CCL11 |
positive regulation of inhibitory G-protein coupled receptor phosphorylation | biological_process | PTGER3 |
positive regulation of innate immune response | biological_process | CCL5, HMGB1, MMP2 |
positive regulation of inositol trisphosphate biosynthetic process | biological_process | LHCGR, GPER1 |
positive regulation of insulin receptor signaling pathway | biological_process | SRC, LEP, IGF2, SIRT1, ADIPOR1 |
positive regulation of insulin secretion | biological_process | GJA1, PSMD9, GHRL, GPER1, NR0B2, IRS2 |
positive regulation of insulin secretion involved in cellular response to glucose stimulus | biological_process | CFTR, HLA-DRB1, CRH, HIF1A |
positive regulation of insulin-like growth factor receptor signaling pathway | biological_process | IGFBP3, IGFBP5, CDH3, IGFBP4, IGF1, GHRH, WNT1 |
positive regulation of integrin activation | biological_process | SRC, CXCL13 |
positive regulation of integrin biosynthetic process | biological_process | AR, TGFB2 |
positive regulation of interferon-alpha biosynthetic process | biological_process | TLR3, TLR9 |
positive regulation of interferon-alpha production | biological_process | HSPD1, HMGB1, TLR4 |
positive regulation of interferon-beta biosynthetic process | biological_process | TLR4, TLR3, TLR9 |
positive regulation of interferon-beta production | biological_process | HMGB1, TLR2, TLR4, TLR3, TLR9 |
positive regulation of interferon-gamma biosynthetic process | biological_process | IL12B, TLR3, TLR9, IL27 |
positive regulation of interferon-gamma production | biological_process | HSPD1, WNT5A, IL12B, IL12A, CCR2, TNF, TLR4, IL1B, LTA, HLA-DPB1, IL18, IL23A, IL2, KLRK1 |
positive regulation of interferon-gamma secretion | biological_process | LGALS9, PTPN22 |
positive regulation of interferon-gamma-mediated signaling pathway | biological_process | HPX |
positive regulation of interleukin-1 alpha secretion | biological_process | CASP1 |
positive regulation of interleukin-1 beta production | biological_process | HSPB1, SMAD3, NOD2, NOD1 |
positive regulation of interleukin-1 beta secretion | biological_process | WNT5A, HMGB1, CCL3, CASP1, CCR2, IFNG, LGALS9, NOD2, CCL19 |
positive regulation of interleukin-1 production | biological_process | TLR4, HDAC2 |
positive regulation of interleukin-1 secretion | biological_process | HMGB1, SAA1 |
positive regulation of interleukin-10 production | biological_process | HSPD1, CD40LG, HMGB1, IL12B, HGF, FCER1G, TLR4, IL4, TLR9, NOD2, IL23A, IL20RB, CD83 |
positive regulation of interleukin-10 secretion | biological_process | PTGER4, LGALS9 |
positive regulation of interleukin-12 biosynthetic process | biological_process | IFNG, TLR4, RELA |
positive regulation of interleukin-12 production | biological_process | HSPD1, CD40LG, HMGB1, CD36, IL12B, CD40, IDO1, HLA-G, IFNG, TLR2, TLR4, TLR3, PLCB1, TLR9, CCL19, AGER, IL23A, CCR7 |
positive regulation of interleukin-12 secretion | biological_process | LGALS9 |
positive regulation of interleukin-13 production | biological_process | GATA3, HLA-E, IL33, IL4 |
positive regulation of interleukin-13 secretion | biological_process | GATA3, PAEP, LGALS9 |
positive regulation of interleukin-17 production | biological_process | IL12B, IL15, TGFB1, NOD2, IL18, IL23A, IL2 |
positive regulation of interleukin-18 production | biological_process | TLR2, TLR9 |
positive regulation of interleukin-2 biosynthetic process | biological_process | IL1A, CD4, IL1B |
positive regulation of interleukin-2 production | biological_process | CCR2, ANXA1, MAP3K7, CD83 |
positive regulation of interleukin-23 production | biological_process | IFNG, CSF2, IL17A |
positive regulation of interleukin-4 production | biological_process | GATA3, CD40LG, HLA-E, LGALS9, IL33, FOXP3, IL20RB |
positive regulation of interleukin-5 biosynthetic process | biological_process | IL9 |
positive regulation of interleukin-5 production | biological_process | GATA3, IL33, IL1RL1 |
positive regulation of interleukin-5 secretion | biological_process | GATA3 |
positive regulation of interleukin-6 biosynthetic process | biological_process | IFNG, IL1B |
positive regulation of interleukin-6 production | biological_process | HSPD1, WNT5A, HMGB1, CD36, IL6R, FCER1G, CCR2, TNF, TLR2, TLR4, TLR3, FIGF, IL1B, IL33, IL6, TLR9, NOD2, NOD1, UCN, CRHR2 |
positive regulation of interleukin-6 secretion | biological_process | F2R, HMGB1, PAEP, LGALS9, IL1B, F2RL1, TWIST1, IL17A, IL17F |
positive regulation of interleukin-8 biosynthetic process | biological_process | APOA2, TNF, TLR4 |
positive regulation of interleukin-8 production | biological_process | PTGER4, TNF, TLR2, TLR4, TLR3, SERPINE1, IL1B, PARK7, ADIPOQ, TLR9, NOD2 |
positive regulation of interleukin-8 secretion | biological_process | F2R, WNT5A, LGALS9, F2RL1 |
positive regulation of intracellular estrogen receptor signaling pathway | biological_process | PAK1 |
positive regulation of intracellular protein transport | biological_process | CDC42 |
positive regulation of intracellular signal transduction | biological_process | SRC, FGF1, TEK |
positive regulation of intrinsic apoptotic signaling pathway | biological_process | BCL2, CLU, TP53, BCL2L11, BCL2L1, BAX, IL20RA |
positive regulation of ion transport | biological_process | LEP, TACR2, IL13 |
positive regulation of IRE1-mediated unfolded protein response | biological_process | BCL2L11, AGR2, BAX |
positive regulation of isotype switching | biological_process | MSH6 |
positive regulation of isotype switching to IgA isotypes | biological_process | TGFB1 |
positive regulation of isotype switching to IgE isotypes | biological_process | STAT6, IL4 |
positive regulation of isotype switching to IgG isotypes | biological_process | CD40, IFNG, IL4, IL2, TBX21 |
positive regulation of JAK-STAT cascade | biological_process | AKR1B1, F2R, CCL5, IL10, KIT, LEP, NOTCH1, PRL, IL5, IL6, HES5, IL24, CYP1B1, IL22, ADIPOR1 |
positive regulation of JNK cascade | biological_process | WNT5A, HMGB1, RASSF2, FLT4, IL1A, TNF, TLR4, CCL21, WNT7A, TLR3, IL1B, CDC42, PLCB1, F2RL1, TLR9, NOD2, CCL19, NOD1, CCR7 |
positive regulation of JUN kinase activity | biological_process | WNT5A, MAP3K7, TNF, IL1B, EDN1, PAK1, TLR9 |
positive regulation of keratinocyte apoptotic process | biological_process | SFRP4 |
positive regulation of keratinocyte differentiation | biological_process | NOTCH1, VDR |
positive regulation of keratinocyte migration | biological_process | MMP9 |
positive regulation of keratinocyte proliferation | biological_process | CDH3, TP63 |
positive regulation of kidney development | biological_process | BMP4, EDNRA |
positive regulation of killing of cells of other organism | biological_process | NOS2, IFNG, FCER2 |
positive regulation of L-dopa biosynthetic process | biological_process | PARK7 |
positive regulation of L-dopa decarboxylase activity | biological_process | PARK7 |
positive regulation of lamellipodium assembly | biological_process | MTOR, HSP90AA1, WNT1, RAC1 |
positive regulation of lamellipodium morphogenesis | biological_process | SRC |
positive regulation of leukocyte adhesion to arterial endothelial cell | biological_process | TNF |
positive regulation of leukocyte chemotaxis | biological_process | IL6R, CXCL5, CXCL10, IL6, F2RL1, ADAM17, CXCL6 |
positive regulation of leukocyte mediated cytotoxicity | biological_process | NOS2, CCL2 |
positive regulation of leukocyte migration | biological_process | VEGFA, ITGA2, KITLG, CCL2, SELP, TACR1 |
positive regulation of leukotriene production involved in inflammatory response | biological_process | SERPINE1 |
positive regulation of ligase activity | biological_process | XRCC4 |
positive regulation of lipase activity | biological_process | RHOC, RHOA |
positive regulation of lipid biosynthetic process | biological_process | AKT1, MTOR, APOE |
positive regulation of lipid catabolic process | biological_process | APOA2, IL1B |
positive regulation of lipid storage | biological_process | NFKB1, C3 |
positive regulation of lipid transport across blood brain barrier | biological_process | APOE |
positive regulation of lipopolysaccharide-mediated signaling pathway | biological_process | MIF, BMP6 |
positive regulation of lipoprotein lipase activity | biological_process | APOA1 |
positive regulation of lipoprotein metabolic process | biological_process | PEMT |
positive regulation of long-term neuronal synaptic plasticity | biological_process | KIT |
positive regulation of long-term synaptic potentiation | biological_process | DRD2 |
positive regulation of low-density lipoprotein particle receptor catabolic process | biological_process | APOE |
positive regulation of lung goblet cell differentiation | biological_process | IL13 |
positive regulation of luteinizing hormone secretion | biological_process | LEP, FOXL2, SMAD4, KISS1 |
positive regulation of lymphangiogenesis | biological_process | VEGFC |
positive regulation of lymphocyte apoptotic process | biological_process | FAS |
positive regulation of lymphocyte proliferation | biological_process | IL12B, TACR1, IL12A, TLR4 |
positive regulation of macroautophagy | biological_process | KDR, HIF1A, SIRT1, PAFAH1B2, DCN |
positive regulation of macrophage activation | biological_process | HSPD1, WNT5A, IL13, THBS1, IL33, IL1RL1 |
positive regulation of macrophage apoptotic process | biological_process | CDKN2A, SIRT1 |
positive regulation of macrophage chemotaxis | biological_process | CCL5, CSF1, CCL2, THBS1, RARRES2, CX3CL1 |
positive regulation of macrophage colony-stimulating factor signaling pathway | biological_process | CSF1 |
positive regulation of macrophage cytokine production | biological_process | WNT5A, CD36, TLR4, CD74 |
positive regulation of macrophage derived foam cell differentiation | biological_process | CD36, NFKB1, CSF1, AGTR1, PLA2G2A, CSF2 |
positive regulation of macrophage differentiation | biological_process | CSF1, LIF, RB1, ID2 |
positive regulation of male gonad development | biological_process | WT1, NR5A1, SEMA3A |
positive regulation of mammary gland epithelial cell proliferation | biological_process | CCND1 |
positive regulation of MAP kinase activity | biological_process | FGFR1, SRC, FGF2, VEGFA, KIT, MIF, CD40, FLT1, KITLG, FLT3, EGFR, FGF1, TGFB1, TNF, PDGFA, ERBB2, EGF, KRAS, EDN1, MST1R, EZH2 |
positive regulation of MAPK cascade | biological_process | FGFR1, F2R, FGFR2, HMGB1, IGFBP3, CD36, KIT, LEP, CTNNB1, KDR, FLT4, TNFRSF1B, IL6R, FLT1, FAS, LIF, TIMP2, IL11, IGFBP4, FLT3, SOX2, INSR, IGF1, ITGB1, PDGFA, TNFRSF11B, IGF2, IL6, PSAP, CDC42, NTRK2, GPER1, KISS1, KSR1, LPAR3 |
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway | biological_process | FGFR1 |
positive regulation of mast cell chemotaxis | biological_process | VEGFA, CCL5, VEGFC, FIGF |
positive regulation of mast cell cytokine production | biological_process | FCER1G |
positive regulation of mast cell degranulation | biological_process | FCER1G, IL13, IL4 |
positive regulation of mast cell proliferation | biological_process | KITLG |
positive regulation of matrix metallopeptidase secretion | biological_process | PTGER4 |
positive regulation of megakaryocyte differentiation | biological_process | GATA2 |
positive regulation of meiotic cell cycle | biological_process | INSR |
positive regulation of meiotic nuclear division | biological_process | WNT5A, WNT4 |
positive regulation of melanin biosynthetic process | biological_process | CDH3 |
positive regulation of melanocyte differentiation | biological_process | BCL2, KITLG |
positive regulation of melanosome transport | biological_process | CDH3 |
positive regulation of membrane potential | biological_process | PIAS3 |
positive regulation of membrane protein ectodomain proteolysis | biological_process | TNFRSF1B, IFNG, APOE, TNF, IL1B, ADAM8 |
positive regulation of memory T cell differentiation | biological_process | IL12B, IL23A |
positive regulation of mesenchymal cell proliferation | biological_process | FGFR1, VEGFA, WNT5A, FGFR2, CTNNB1, WNT2, MYC, PDGFA, TP63, IRS2 |
positive regulation of mesenchymal stem cell proliferation | biological_process | BMP4 |
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological_process | LIF, PAX2 |
positive regulation of metalloendopeptidase activity | biological_process | STAT3 |
positive regulation of metanephric cap mesenchymal cell proliferation | biological_process | MYC |
positive regulation of metanephric DCT cell differentiation | biological_process | PAX2 |
positive regulation of metanephric glomerular visceral epithelial cell development | biological_process | ADIPOQ |
positive regulation of metanephric glomerulus development | biological_process | AGTR2, PAX2 |
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological_process | PDGFA |
positive regulation of metanephric ureteric bud development | biological_process | WT1 |
positive regulation of methylation-dependent chromatin silencing | biological_process | DNMT1 |
positive regulation of MHC class II biosynthetic process | biological_process | IL10, IFNG, TLR4, IL4, SIRT1 |
positive regulation of microglial cell migration | biological_process | CSF1 |
positive regulation of microtubule polymerization | biological_process | CDKN1B |
positive regulation of miRNA metabolic process | biological_process | NFKB1, RELA |
positive regulation of mismatch repair | biological_process | HMGB1 |
positive regulation of mitochondrial depolarization | biological_process | KDR, DCN |
positive regulation of mitochondrial DNA replication | biological_process | STOML2 |
positive regulation of mitochondrial electron transport, NADH to ubiquinone | biological_process | PARK7 |
positive regulation of mitochondrial fission | biological_process | KDR, DCN |
positive regulation of mitochondrial membrane permeability involved in apoptotic process | biological_process | ATF2, BCL2L11, BAX |
positive regulation of mitochondrial membrane potential | biological_process | GSK3B, STOML2 |
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological_process | GSK3B, BAX |
positive regulation of mitochondrial translation | biological_process | C1QBP |
positive regulation of mitophagy | biological_process | PARK7, HIF1A |
positive regulation of mitotic cell cycle | biological_process | CCNB1, BRCA2, BIRC5, EIF4EBP1 |
positive regulation of mitotic cell cycle phase transition | biological_process | TMOD3 |
positive regulation of mitotic cell cycle spindle assembly checkpoint | biological_process | XRCC3 |
positive regulation of mitotic metaphase/anaphase transition | biological_process | RB1 |
positive regulation of mitotic nuclear division | biological_process | AURKA, INSR, IGF1, IL1A, IL1B, EGF, IGF2, EDN1 |
positive regulation of monocyte aggregation | biological_process | CD44 |
positive regulation of monocyte chemotactic protein-1 production | biological_process | LGALS9, IL1B, ADIPOQ, TWIST1 |
positive regulation of monocyte chemotaxis | biological_process | CCL5, HMGB1, CCR1, CCL2, CCR2, CXCL12, CXCL10, SERPINE1, AIF1 |
positive regulation of monocyte differentiation | biological_process | CSF1, JUN |
positive regulation of monocyte extravasation | biological_process | CCR2 |
positive regulation of mononuclear cell migration | biological_process | LGALS3, TNF, IL4 |
positive regulation of mononuclear cell proliferation | biological_process | IL12B, CSF1, IL12A |
positive regulation of monophenol monooxygenase activity | biological_process | CDH3 |
positive regulation of mRNA 3'-end processing | biological_process | CCNB1 |
positive regulation of mucus secretion | biological_process | PTGER4 |
positive regulation of multicellular organism growth | biological_process | BCL2, DRD2, CSF1, GHRH, HSF1, GHRL |
positive regulation of muscle cell differentiation | biological_process | CTNNB1, CTNNA1, CDC42 |
positive regulation of muscle hyperplasia | biological_process | AIF1 |
positive regulation of myelination | biological_process | HGF, NRG1, DICER1 |
positive regulation of myeloid cell apoptotic process | biological_process | ADIPOQ |
positive regulation of myeloid cell differentiation | biological_process | HMGB1, LEP, JAG1 |
positive regulation of myeloid dendritic cell activation | biological_process | KLRK1 |
positive regulation of myeloid dendritic cell chemotaxis | biological_process | CCL21 |
positive regulation of myeloid leukocyte cytokine production involved in immune response | biological_process | MIF |
positive regulation of myeloid leukocyte differentiation | biological_process | KITLG |
positive regulation of myoblast differentiation | biological_process | IGFBP3, PLCB1 |
positive regulation of myoblast fusion | biological_process | IL4, GDF15 |
positive regulation of myoblast proliferation | biological_process | SOX15 |
positive regulation of myofibroblast contraction | biological_process | PTGER3 |
positive regulation of myosin light chain kinase activity | biological_process | IL1B |
positive regulation of myotube differentiation | biological_process | MMP14, MTOR |
positive regulation of NAD(P)H oxidase activity | biological_process | AGTR1 |
positive regulation of NAD+ ADP-ribosyltransferase activity | biological_process | TGFB1 |
positive regulation of natural killer cell activation | biological_process | IL12B, IL12A, IL23A |
positive regulation of natural killer cell chemotaxis | biological_process | CCL5, CCL3, CXCL14, CCL7 |
positive regulation of natural killer cell differentiation | biological_process | AXL, IL15, GAS6 |
positive regulation of natural killer cell mediated cytotoxicity | biological_process | IL12A, CADM1, KLRK1 |
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | biological_process | IL12B, IL12A, KLRK1 |
positive regulation of natural killer cell mediated immunity | biological_process | HLA-E |
positive regulation of natural killer cell proliferation | biological_process | IL12B, IL15, IL18, IL23A |
positive regulation of necrotic cell death | biological_process | IL17A |
positive regulation of nephron tubule epithelial cell differentiation | biological_process | PROM1 |
positive regulation of neural precursor cell proliferation | biological_process | DLL4 |
positive regulation of neuroblast proliferation | biological_process | VEGFA, CTNNB1, NOTCH1, DRD2, VEGFC, HIF1A, CX3CL1 |
positive regulation of neurofibrillary tangle assembly | biological_process | CLU, APOE |
positive regulation of neurogenesis | biological_process | OPRM1, SERPINF1, WNT2, MTOR, STAR, GPER1 |
positive regulation of neuron apoptotic process | biological_process | GSK3B, CTNNB1, ATF2, CCL3, CASP3, FASLG, JUN, TP53, MAP2K7, BCL2L11, CDC42, TGFB2, BAX, ATM, AGER |
positive regulation of neuron death | biological_process | GSK3B, CLU, MTOR, APOE, ATM, AGER |
positive regulation of neuron differentiation | biological_process | FGFR1, BCL6, BMP4, CCL5, GATA2, TIMP2, BMP6, ZEB1, CCR2, CXCL12, ITGB1, IFNG, IL6, DNMT3B, RHOA |
positive regulation of neuron maturation | biological_process | BCL2, MTOR |
positive regulation of neuron migration | biological_process | SEMA3A |
positive regulation of neuron projection development | biological_process | FGFR1, BMP4, WNT5A, ITGA3, SERPINF1, NME1, LIF, PTN, MTOR, ITGB1, FYN, NTRK2, KAT2B |
positive regulation of neuron projection regeneration | biological_process | HGF |
positive regulation of neurotransmitter secretion | biological_process | GPER1 |
positive regulation of neutrophil apoptotic process | biological_process | ANXA1 |
positive regulation of neutrophil chemotaxis | biological_process | CXCL8, EDNRA, CXCL1, CXCL2, CCL21, IL1B, CD74, RAC1, C1QBP, CCL19, IL23A, CCR7 |
positive regulation of neutrophil extravasation | biological_process | PTGER4, PTGER3, ADAM8 |
positive regulation of neutrophil mediated killing of gram-negative bacterium | biological_process | F2RL1 |
positive regulation of NF-kappaB import into nucleus | biological_process | IL12B, PTGS2, GREM1, TNF, LGALS9, TLR2, TLR4, TLR3, IL1B, TLR9, IL18, CCL19, IL23A, RHOA |
positive regulation of NF-kappaB transcription factor activity | biological_process | CD40LG, WNT5A, CLU, NFKB1, AR, CD40, IL6R, GREM1, TGFB1, CLOCK, MAP3K7, PRKCB, LTF, TNF, LGALS9, TLR2, TLR4, TLR3, IL1B, ITGB2, KRAS, ICAM1, AMH, CAT, IL6, RELA, TLR9, NOD2, NFKB2, NOD1, AGER, ADAM8, CRHR2 |
positive regulation of NFAT protein import into nucleus | biological_process | TNF |
positive regulation of NIK/NF-kappaB signaling | biological_process | HMGB1, ACTN4, TNF, NOD2, NOD1 |
positive regulation of nitric oxide biosynthetic process | biological_process | CLU, OPRM1, AKT1, AGTR2, PTX3, MTOR, PTGS2, ESR1, INSR, HSP90AA1, EGFR, IFNG, TNF, TLR4, IL1B, ITGB2, ICAM1, IL6, EDN1, AIF1, KLRK1 |
positive regulation of nitric-oxide synthase activity | biological_process | AKT1, AGTR2, ESR1, APOE, TERT, KRAS, FCER2, HIF1A, NOD1, SCARB1 |
positive regulation of nitric-oxide synthase biosynthetic process | biological_process | KDR, CCL2, TLR2, TLR4, FCER2, TLR9, NOD2 |
positive regulation of NK T cell activation | biological_process | IL12B, IL12A, IL23A |
positive regulation of NK T cell proliferation | biological_process | IL12B, IL18, IL23A |
positive regulation of NLRP3 inflammasome complex assembly | biological_process | CD36, TLR4 |
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological_process | SMAD2, NODAL |
positive regulation of non-canonical Wnt signaling pathway | biological_process | WNT5A |
positive regulation of non-motile cilium assembly | biological_process | Sep-09 |
positive regulation of norepinephrine secretion | biological_process | OXTR |
positive regulation of Notch signaling pathway | biological_process | STAT3, KIT, NOTCH1, WNT1, HES5, NOD2, TP63, JAG1, DLL4 |
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological_process | TOB1 |
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological_process | TOB1 |
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway | biological_process | TLR4 |
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_process | TLR4 |
positive regulation of odontogenesis | biological_process | EDNRA, TGFB1, EDN1 |
positive regulation of odontogenesis of dentin-containing tooth | biological_process | CSF1 |
positive regulation of oligodendrocyte differentiation | biological_process | PPARG, MTOR, HDAC2, CXCR4 |
positive regulation of oocyte maturation | biological_process | AURKA |
positive regulation of optic nerve formation | biological_process | PAX2 |
positive regulation of organ growth | biological_process | YAP1 |
positive regulation of ossification | biological_process | BMP4, WNT5A, PTGER4, TACR1, TGFB2 |
positive regulation of osteoblast differentiation | biological_process | BMP4, GJA1, CTNNB1, PTGER4, IL6R, IL6ST, HGF, BMP6, IGF1, LTF, BMPR1B, CYR61, IL6, TP63, JAG1, DLX5, WNT4 |
positive regulation of osteoblast proliferation | biological_process | ITGAV, LTF, CYR61, HPSE |
positive regulation of osteoclast differentiation | biological_process | CCL5, IL12B, CSF1, CCR1, CA2, IFNG, TNF, FOS, CSF1R, KLF10, IL23A, IL17A |
positive regulation of ovarian follicle development | biological_process | PTGER4 |
positive regulation of ovulation | biological_process | INHBA, PLAU |
positive regulation of oxidative phosphorylation uncoupler activity | biological_process | PARK7 |
positive regulation of oxidative stress-induced cell death | biological_process | MMP3 |
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological_process | SOD1, PARK7 |
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological_process | MCL1 |
positive regulation of oxidoreductase activity | biological_process | NOD2, ATP7A |
positive regulation of p38MAPK cascade | biological_process | XDH, VEGFA, LEP |
positive regulation of pancreatic stellate cell proliferation | biological_process | IL13 |
positive regulation of pancreatic trypsinogen secretion | biological_process | MMP13 |
positive regulation of pathway-restricted SMAD protein phosphorylation | biological_process | INHBA, BMP4, ENG, BMP6, TGFB1, INHA, MSTN, GDF9, TGFB2, SMAD4, NODAL, GDF15 |
positive regulation of penile erection | biological_process | OXTR |
positive regulation of peptidase activity | biological_process | FBLN1, MMP14, FN1 |
positive regulation of peptide hormone secretion | biological_process | FGA |
positive regulation of peptidyl-cysteine S-nitrosylation | biological_process | ACE |
positive regulation of peptidyl-serine phosphorylation | biological_process | GSK3B, BCL2, TXN, VEGFA, WNT5A, MIF, AKT1, BRAF, CD44, LIF, IL11, PIK3CA, TGFB1, TNF, LATS1, SPRY2, IL6, CDC42, PARK7, NTRK2, GAS6, PAK1, UCN, ANGPT1 |
positive regulation of peptidyl-serine phosphorylation of STAT protein | biological_process | LIF, IFNG |
positive regulation of peptidyl-threonine phosphorylation | biological_process | GSK3B, WNT5A, MAPK1, CHI3L1, TGFB1, EGF, PLK1 |
positive regulation of peptidyl-tyrosine autophosphorylation | biological_process | VEGFA, ACE, GREM1 |
positive regulation of peptidyl-tyrosine phosphorylation | biological_process | SRC, VEGFA, CD36, MIF, IL6R, HGF, CD44, KITLG, TDGF1, LIF, IL11, EFNA1, MTOR, VEGFC, IGF1, ITGB3, ITGB1, TGFB1, TP53, CD4, NRP1, EGF, IGF2, ICAM1, CD74, IL4, IL5, IL6, NRG1, ADIPOQ, ANGPT1 |
positive regulation of peripheral T cell tolerance induction | biological_process | FOXP3 |
positive regulation of PERK-mediated unfolded protein response | biological_process | AGR2 |
positive regulation of peroxisome proliferator activated receptor signaling pathway | biological_process | LEP |
positive regulation of phagocytosis | biological_process | MBL2, GATA2, PTX3, FCER1G, AHSG, TNF, C3, IL1B, GAS6 |
positive regulation of phagocytosis, engulfment | biological_process | PPARG, CD36, ITGA2, GATA2, F2RL1, AGER |
positive regulation of phosphatidylinositol 3-kinase activity | biological_process | SRC, FGF2, KIT, PDGFRA, FLT1, FLT3, TGFB1, CCL21, CDC42, RAC1, PTK2, TEK, NOD2, CCL19, CCR7 |
positive regulation of phosphatidylinositol 3-kinase signaling | biological_process | FGFR1, FSHR, F2R, CCL5, KIT, LEP, ERBB3, KDR, PDGFRA, HGF, FLT1, SELP, FLT3, IGF1, PDGFA, FYN, CAT, TGFB2, PTK2, NRG1, NTRK2, TEK, F2RL1, SIRT1, GPER1, ANGPT1, DCN |
positive regulation of phospholipase A2 activity | biological_process | AGTR1 |
positive regulation of phospholipase activity | biological_process | FGFR1, FGFR2, CYR61 |
positive regulation of phospholipase C activity | biological_process | FGFR1, FGF2, KIT, PDGFRA, FLT1, ESR1 |
positive regulation of phospholipid efflux | biological_process | APOE |
positive regulation of phosphoprotein phosphatase activity | biological_process | AGTR2 |
positive regulation of phosphorylation | biological_process | ITGA6, CCL5, MIF, AR, EGFR, ANG, THBS1, EGF |
positive regulation of pinocytosis | biological_process | AXL, ACTN4 |
positive regulation of platelet activation | biological_process | SELP, TLR4 |
positive regulation of platelet-derived growth factor production | biological_process | PTGS2 |
positive regulation of platelet-derived growth factor receptor signaling pathway | biological_process | SRC, F3 |
positive regulation of podosome assembly | biological_process | SRC, TNF, CSF2, IL5 |
positive regulation of positive chemotaxis | biological_process | VEGFA, F3, KDR, ITGA2, SMAD3, F2RL1 |
positive regulation of postsynaptic membrane organization | biological_process | APOE |
positive regulation of potassium ion transmembrane transporter activity | biological_process | AGER |
positive regulation of potassium ion transport | biological_process | DPP6 |
positive regulation of presynaptic membrane organization | biological_process | APOE |
positive regulation of pri-miRNA transcription from RNA polymerase II promoter | biological_process | STAT3, JUN, TERT, FOS, HIF1A |
positive regulation of production of miRNAs involved in gene silencing by miRNA | biological_process | EGFR |
positive regulation of progesterone secretion | biological_process | RETN |
positive regulation of programmed cell death | biological_process | CDKN1A, TNF |
positive regulation of prostaglandin biosynthetic process | biological_process | PLA2G4A, PTGS2, ANXA1 |
positive regulation of prostaglandin secretion | biological_process | IL1B, EDN1 |
positive regulation of prostaglandin secretion involved in immune response | biological_process | MIF |
positive regulation of prostaglandin-E synthase activity | biological_process | NOD2 |
positive regulation of prostaglandin-endoperoxide synthase activity | biological_process | EDN1, NOD2 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological_process | GCLC, GSK3B, CLU, AKT1, AURKA, SMAD7, PSMD10, IL33, PLK1 |
positive regulation of protein autophosphorylation | biological_process | SRC, VEGFA, RASSF2, VEGFC, PDGFA |
positive regulation of protein binding | biological_process | GSK3B, BMP4, WNT5A, TERT |
positive regulation of protein catabolic process | biological_process | GSK3B, WNT5A, GJA1, CDKN1B, C4BPA, FOXO1, STX5 |
positive regulation of protein complex assembly | biological_process | GSK3B, VEGFA, TGFB1, TNF |
positive regulation of protein complex disassembly | biological_process | TNF |
positive regulation of protein dephosphorylation | biological_process | TGFB1 |
positive regulation of protein export from nucleus | biological_process | GSK3B, TP53, IL1B, GAS6 |
positive regulation of protein homodimerization activity | biological_process | PARK7 |
positive regulation of protein homooligomerization | biological_process | FAS, BCL2L11 |
positive regulation of protein import into nucleus | biological_process | LEP, TGFB1 |
positive regulation of protein import into nucleus, translocation | biological_process | BRCA1, IGF1, HSP90AA1, IL6 |
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological_process | BCL2, TP53, BCL2L11, YWHAH, TP63 |
positive regulation of protein K63-linked ubiquitination | biological_process | PTPN22 |
positive regulation of protein kinase A signaling | biological_process | MIF, ADIPOQ |
positive regulation of protein kinase activity | biological_process | WNT5A, RASSF2, CSF1, SDC4, TNF, CD4, CCL21, CYR61, PTK2, NRG1, GAS6, ADIPOQ, CCL19, CCR7 |
positive regulation of protein kinase B signaling | biological_process | SRC, TXN, GATA3, CHI3L1, F3, LEP, CCL3, AXL, IGFBP5, MTOR, AKR1C3, AKR1C2, INSR, EGFR, TGFB1, TNF, PDGFA, CCL21, SPRY2, THBS1, GPX1, IGF2, IL6, C1QBP, PTK2, NRG1, PARK7, HPSE, GAS6, TEK, CCL19, MST1R, ADAM8, ANGPT1, CCR7 |
positive regulation of protein kinase C activity | biological_process | WNT5A |
positive regulation of protein kinase C signaling | biological_process | VEGFA, WNT5A, FLT4, CD40 |
positive regulation of protein kinase D signaling | biological_process | VEGFA |
positive regulation of protein localization to cell surface | biological_process | TNF, NRG1 |
positive regulation of protein localization to early endosome | biological_process | VEGFA |
positive regulation of protein localization to nucleolus | biological_process | TERT |
positive regulation of protein localization to nucleus | biological_process | AKT1, LIF, TGFB1, FYN, PLK1, TGFB2, PARK7, CDKN2A |
positive regulation of protein localization to synapse | biological_process | WNT5A, WNT7A |
positive regulation of protein O-linked glycosylation | biological_process | IL15 |
positive regulation of protein oligomerization | biological_process | TP53, MMP1, MMP3, BAX |
positive regulation of protein phosphorylation | biological_process | CCND1, VEGFA, BMP4, WNT5A, HMGB1, MMP9, MIF, AKT1, PTGER4, KDR, FLT4, CD40, ENG, EDNRA, MTOR, PTGER3, CHEK2, INSR, ITGB3, EGFR, FGF1, TGFB1, TNF, C3, ERBB2, CYR61, MAP2K7, TLR3, ANXA2, IL1B, KRAS, IGF2, WNT1, IL4, CRH, CSF1R, CDC42, RAC1, PTK2, NTRK2, GAS6, PLAUR, TEK, PAK1, ADIPOQ, AIF1, RARRES2, SIRT1, ADAM17, AGER, GPER1, UCN, IL2 |
positive regulation of protein polyubiquitination | biological_process | HAMP |
positive regulation of protein processing | biological_process | ADAM8 |
positive regulation of protein secretion | biological_process | PTGER4, BMP6, IL13, VEGFC, IGF1, ANG, TGFB1, FGA, IL1A, TGFB2, ADAM8 |
positive regulation of protein serine/threonine kinase activity | biological_process | SRC, LTF, SPRY2, IGF2, CSF1R, EZH2, RHOA |
positive regulation of protein sumoylation | biological_process | ARNT, CDKN2A, PIAS3 |
positive regulation of protein targeting to membrane | biological_process | CCL2, ERBB2 |
positive regulation of protein targeting to mitochondrion | biological_process | NRG1, PEMT |
positive regulation of protein transport | biological_process | SRC, TNF |
positive regulation of protein tyrosine kinase activity | biological_process | CCL5, ERBB3, ACE, GREM1, CSF1R, NRG1, GAS6, GHRL |
positive regulation of protein ubiquitination | biological_process | BRCA1, SMAD7, PSMD10, ANGPT1 |
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological_process | CLU, CCDC22, EGF, PTEN, PTK2 |
positive regulation of proteolysis | biological_process | PLK1, HDAC2 |
positive regulation of pseudopodium assembly | biological_process | KIT, CCL21, CDC42, F2RL1, CCR7 |
positive regulation of pyrroline-5-carboxylate reductase activity | biological_process | PARK7 |
positive regulation of Rac protein signal transduction | biological_process | KRAS |
positive regulation of Ras protein signal transduction | biological_process | CSF1, KITLG, IGF1, NRG1 |
positive regulation of reactive oxygen species biosynthetic process | biological_process | PARK7 |
positive regulation of reactive oxygen species metabolic process | biological_process | XDH, CD36, LEP, CDKN1A, AGTR1, AKR1C3, TP53, THBS1, PLAU, NFE2L2, AGER |
positive regulation of receptor activity | biological_process | GREM1, ANXA2, IGF2, SRA1 |
positive regulation of receptor binding | biological_process | MMP9 |
positive regulation of receptor biosynthetic process | biological_process | EDN1, HDAC2, HIF1A, HDAC1 |
positive regulation of receptor catabolic process | biological_process | HAMP |
positive regulation of receptor clustering | biological_process | TGFB1 |
positive regulation of receptor internalization | biological_process | VEGFA, DRD2, SELE, GREM1, HAMP, ANGPT1, SFRP4 |
positive regulation of receptor-mediated endocytosis | biological_process | CCL21, SERPINE1, TF, CCL19 |
positive regulation of regulatory T cell differentiation | biological_process | HLA-G, TGFB1, FOXP3, IL2 |
positive regulation of release of cytochrome c from mitochondria | biological_process | MMP9, TNFSF10, TP53, BCL2L11, BAX, PLAUR, GPER1 |
positive regulation of release of sequestered calcium ion into cytosol | biological_process | F2R, CXCR3, EDNRA, IL13, CXCL10, BAX, GPER1 |
positive regulation of renal albumin absorption | biological_process | ADIPOQ |
positive regulation of renal sodium excretion | biological_process | PTGER4, DRD2, AGTR2, TACR1, EDN1 |
positive regulation of renin secretion into blood stream | biological_process | F2RL1 |
positive regulation of respiratory burst | biological_process | INSR |
positive regulation of response to cytokine stimulus | biological_process | WNT5A |
positive regulation of response to DNA damage stimulus | biological_process | HMGA2, MYC |
positive regulation of response to food | biological_process | GHRL |
positive regulation of response to interferon-gamma | biological_process | HPX |
positive regulation of retinal ganglion cell axon guidance | biological_process | VEGFA, NRP1 |
positive regulation of Rho protein signal transduction | biological_process | F2R, APOA1, RAC1, F2RL1 |
positive regulation of RNA splicing | biological_process | PIK3R1 |
positive regulation of saliva secretion | biological_process | TACR1 |
positive regulation of sarcomere organization | biological_process | EDN1 |
positive regulation of satellite cell activation involved in skeletal muscle regeneration | biological_process | SOX15 |
positive regulation of Schwann cell differentiation | biological_process | RELA, DICER1 |
positive regulation of sensory perception of pain | biological_process | MTOR, P2RX3 |
positive regulation of sequence-specific DNA binding transcription factor activity | biological_process | PPARG, IL10, KIT, AKT1, CTNNB1, ATF2, WNT2, ESR1, TNF, IL1B, WNT1, IL4, IL5, IL6, PTEN, PARK7, ESR2, PPRC1, NODAL |
positive regulation of serotonin secretion | biological_process | CRHR2 |
positive regulation of signal transduction | biological_process | CRK, GATA3, TOB1, ADIPOQ, GRB14 |
positive regulation of signal transduction by p53 class mediator | biological_process | CDKN2A, CHD5 |
positive regulation of skeletal muscle acetylcholine-gated channel clustering | biological_process | PTN |
positive regulation of skeletal muscle fiber development | biological_process | BCL2 |
positive regulation of skeletal muscle hypertrophy | biological_process | MTOR |
positive regulation of skeletal muscle tissue development | biological_process | CTNNB1 |
positive regulation of SMAD protein import into nucleus | biological_process | BMP4, BMP6, TGFB1, POU5F1, SMAD4, NODAL |
positive regulation of smooth muscle cell apoptotic process | biological_process | IL12B, CDKN2A, IL12A, IFNG |
positive regulation of smooth muscle cell chemotaxis | biological_process | AIF1 |
positive regulation of smooth muscle cell differentiation | biological_process | TGFB1 |
positive regulation of smooth muscle cell migration | biological_process | BCL2, SRC, CCL5, F3, PTGER4, ITGA2, IGF1, NRP1, PLAU, AGER, POSTN, RETN |
positive regulation of smooth muscle cell proliferation | biological_process | GSK3B, AKR1B1, BMP4, CCL5, FGFR2, SHC1, IL6R, ITGA2, FLT1, HMOX1, MTOR, IL13, PTGS2, IGF1, JUN, TNF, IL6, EDN1, HIF1A, FOXP1, HES5, AIF1, ID2, AGER, CX3CL1, RETN |
positive regulation of smooth muscle contraction | biological_process | F2R, ITGA2, TACR2, TACR1, PTGS1, PTGS2, ADA, EDN1 |
positive regulation of smooth muscle contraction involved in micturition | biological_process | PTGER3 |
positive regulation of smoothened signaling pathway | biological_process | CTNNA1, IHH |
positive regulation of sodium ion transport | biological_process | AKT1, SGK1 |
positive regulation of sodium:proton antiporter activity | biological_process | ACTN4 |
positive regulation of sprouting angiogenesis | biological_process | FGF2, HMGB1, JAK1, FGF1 |
positive regulation of STAT protein import into nucleus | biological_process | LEP, IL6 |
positive regulation of stem cell differentiation | biological_process | GSK3B |
positive regulation of stem cell population maintenance | biological_process | YAP1 |
positive regulation of stem cell proliferation | biological_process | HMGA2, EPCAM, TERT |
positive regulation of steroid hormone biosynthetic process | biological_process | CYP17A1 |
positive regulation of store-operated calcium channel activity | biological_process | BMP4 |
positive regulation of stress fiber assembly | biological_process | SDC4, BRAF, TACR1, MTOR, APOA1, RAC1, SMAD3, PAK1, LIMK1, WNT4, KISS1R, RHOA |
positive regulation of stress-activated MAPK cascade | biological_process | TLR4, IL1B, TGFB2, NOD2, NOD1, CRHR2 |
positive regulation of striated muscle cell differentiation | biological_process | NRG1 |
positive regulation of striated muscle tissue development | biological_process | GJA1 |
positive regulation of substance P secretion | biological_process | PTGER4 |
positive regulation of substance P secretion, neurotransmission | biological_process | PTGER4 |
positive regulation of substrate adhesion-dependent cell spreading | biological_process | BRAF, FGA, APOA1, CDC42, RAC1, C1QBP, OLFM4 |
positive regulation of substrate-dependent cell migration, cell attachment to substrate | biological_process | FBLN1, FN1 |
positive regulation of superoxide anion generation | biological_process | GSTP1, TGFB1, SOD1, CRP, F2RL1 |
positive regulation of superoxide dismutase activity | biological_process | TNF, PARK7 |
positive regulation of supramolecular fiber organization | biological_process | GPX1 |
positive regulation of synapse assembly | biological_process | BDNF, OXTR, WNT7A, NTRK2, GHRL |
positive regulation of synapse structural plasticity | biological_process | CDC42 |
positive regulation of synaptic plasticity | biological_process | PTGS2 |
positive regulation of synaptic transmission | biological_process | CCL2, KISS1R, KISS1, RETN |
positive regulation of synaptic transmission, cholinergic | biological_process | TACR1, IFNG |
positive regulation of synaptic transmission, GABAergic | biological_process | TACR1, OXTR, CA2 |
positive regulation of synaptic transmission, glutamatergic | biological_process | OXTR, PTGS2, NTRK2 |
positive regulation of systemic arterial blood pressure | biological_process | ENG |
positive regulation of T cell activation | biological_process | HSPD1, CCL2, CCR2, MAP3K7, CD4, ADA, HLA-DPB1 |
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological_process | LGALS9 |
positive regulation of T cell anergy | biological_process | FOXP3 |
positive regulation of T cell apoptotic process | biological_process | CCL5, IDO1 |
positive regulation of T cell chemotaxis | biological_process | WNT5A, CCL5, CCR2, CXCL13, ADAM17 |
positive regulation of T cell costimulation | biological_process | CCR7 |
positive regulation of T cell cytokine production | biological_process | MAP3K7 |
positive regulation of T cell differentiation | biological_process | GATA3, IL12A, ADA, IL2RA, CD74, IL4, IL2 |
positive regulation of T cell differentiation in thymus | biological_process | ADA, ADAM8, IHH |
positive regulation of T cell mediated cytotoxicity | biological_process | IL12B, HLA-E, IL12A, HLA-A, IL23A |
positive regulation of T cell mediated immune response to tumor cell | biological_process | HSPD1 |
positive regulation of T cell mediated immunity | biological_process | IL1B |
positive regulation of T cell migration | biological_process | CCL5, CXCL12, CXCL10, CCL21, AIF1, ADAM8 |
positive regulation of T cell proliferation | biological_process | CD40LG, CCL5, IL12B, LEP, IL6ST, IL15, VCAM1, IL12A, IFNG, ANXA1, CD4, IL1B, PNP, IL2RA, HLA-DPB1, IL4, IL6, AIF1, CCL19, IL23A, IL2 |
positive regulation of T cell receptor signaling pathway | biological_process | ADA, CCR7 |
positive regulation of T cell tolerance induction | biological_process | IDO1, HLA-G, FOXP3 |
positive regulation of T-helper 1 cell differentiation | biological_process | ANXA1, CCL19 |
positive regulation of T-helper 1 type immune response | biological_process | IL12B, CCR2, IL23A |
positive regulation of T-helper 17 cell lineage commitment | biological_process | IL12B, IL23A |
positive regulation of T-helper 17 type immune response | biological_process | IL12B, IL23A |
positive regulation of T-helper 2 cell cytokine production | biological_process | GATA3 |
positive regulation of T-helper 2 cell differentiation | biological_process | IL6 |
positive regulation of tau-protein kinase activity | biological_process | CLU |
positive regulation of telomerase activity | biological_process | MAPK1, CTNNB1, GREM1, MAP2K7 |
positive regulation of telomerase catalytic core complex assembly | biological_process | ATM |
positive regulation of telomere capping | biological_process | MAPK1, MAP2K7 |
positive regulation of telomere maintenance via telomerase | biological_process | MAPK1, CTNNB1, MAP2K7, ATM |
positive regulation of telomere maintenance via telomere lengthening | biological_process | ATM |
positive regulation of thymocyte apoptotic process | biological_process | WNT5A, TP53, ADAM8 |
positive regulation of thyroid hormone generation | biological_process | GATA3 |
positive regulation of tissue remodeling | biological_process | IL12B, IL15, IL18, IL23A, IL2 |
positive regulation of tolerance induction | biological_process | HLA-G |
positive regulation of toll-like receptor 2 signaling pathway | biological_process | HMGB1, F2RL1 |
positive regulation of toll-like receptor 3 signaling pathway | biological_process | F2RL1, PTPN22 |
positive regulation of toll-like receptor 4 signaling pathway | biological_process | HMGB1, LTF, F2RL1, PTPN22 |
positive regulation of toll-like receptor 9 signaling pathway | biological_process | HMGB1 |
positive regulation of toll-like receptor signaling pathway | biological_process | TLR2, TLR3, TLR9 |
positive regulation of TOR signaling | biological_process | LEP, GAS6 |
positive regulation of TRAIL production | biological_process | HLA-E |
positive regulation of TRAIL-activated apoptotic signaling pathway | biological_process | TIMP3, PTEN |
positive regulation of transcription factor import into nucleus | biological_process | CDH1, PIK3R1, SMAD3 |
positive regulation of transcription from RNA polymerase I promoter | biological_process | ERBB2 |
positive regulation of transcription from RNA polymerase II promoter | biological_process | GSK3B, EGR1, GATA3, ITGA6, INHBA, YAP1, FGF2, VEGFA, MET, STAT3, BMP4, CDX1, WNT5A, HMGA2, PPARG, TNFRSF1A, FGFR2, HMGB1, PIK3R1, IL10, AKT1, CTNNB1, ATF2, EPCAM, BRCA1, NFKB1, HMGA1, AR, WNT2, AHR, NOTCH1, DRD2, CXCR3, VDR, CD40, ENG, GATA2, HGF, USF1, LIF, STAT6, HOXA10, WT1, IL11, HNF1B, BMP6, ARNT, SOX2, ZEB1, ESR1, IGF1, GREM1, EGFR, JUN, FGF1, IFNG, TGFB1, CLOCK, FSTL3, IL1A, TP53, TNF, MYC, CXCL10, TLR2, TLR4, BMPR1B, SMAD7, MEIS1, NR5A2, CYR61, RB1, WNT7A, SOX15, FOS, TLR3, NR3C1, SERPINE1, PGR, IL1B, IL33, CGA, FSHB, WNT1, IL4, IL6, EDN1, COPS5, YBX1, HDAC2, SMAD3, RELA, NRG1, FOXL2, PARK7, HIF1A, HES5, ATP1B4, FOXO1, NR5A1, HSF1, SMAD2, F2RL1, HEY1, TLR9, NFE2L2, NOD2, ESR2, PPARA, NFKB2, POU5F1, KAT2B, HDAC1, FOXP3, SIRT1, SMAD4, TWIST1, GPER1, CDKN2A, TP63, GATA6, JAG1, PAX2, USF2, UCN, IL23A, DLX5, IL2, IHH, IL17A, PPRC1, IL17F, NODAL, NANOG, GATA5, AHRR, TET3, MAF, DCN, TET2, TET1, LILRB1, CREB3L1 |
positive regulation of transcription from RNA polymerase II promoter by glucose | biological_process | USF1, USF2 |
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological_process | TP53, CREB3L1 |
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological_process | VEGFA, NOTCH1, HIF1A |
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress | biological_process | NFE2L2 |
positive regulation of transcription from RNA polymerase II promoter in response to stress | biological_process | MUC1, NFE2L2 |
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | biological_process | SMAD4, DLX5 |
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | biological_process | GREM1 |
positive regulation of transcription from RNA polymerase III promoter | biological_process | AR, MTOR, ERBB2 |
positive regulation of transcription initiation from RNA polymerase II promoter | biological_process | HNF1B |
positive regulation of transcription involved in G1/S transition of mitotic cell cycle | biological_process | ID2 |
positive regulation of transcription of Notch receptor target | biological_process | NOTCH1, NOTCH4 |
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter | biological_process | MTOR |
positive regulation of transcription regulatory region DNA binding | biological_process | GATA3, HMGA2, IGF1, TGFB1, RB1, PARK7, TWIST1 |
positive regulation of transcription, DNA-templated | biological_process | EGR1, SRC, CDH1, GATA3, INHBA, FGF2, STAT3, NR2F2, BMP4, F2R, WNT5A, HMGA2, PPARG, MAPK1, IL10, CTNNB1, BRCA1, NFKB1, HMGA1, AR, AHR, NOTCH1, AGTR2, BRCA2, USF1, WT1, HNF1B, MDK, ARNT, HOXA11, SOX2, CHEK2, PSMD9, ESR1, INSR, IGF1, GREM1, JUN, IFNG, TGFB1, CLOCK, TP53, TNF, MYC, NR5A2, RB1, WNT7A, ARID1A, SNAI1, MSTN, FOS, TGFB1I1, IL1B, EGF, WNT1, IL4, IL5, IL6, RUNX3, HDAC2, SMAD3, RELA, FOXL2, HIF1A, HES5, FOXO1, PLCB1, NR5A1, SMAD2, NFE2L2, ESR2, PPARA, KAT2B, HDAC1, FOXP3, ID2, SMAD4, YWHAH, PIM2, CDKN2A, TP63, GATA6, NAA15, PAX2, USF2, DLX5, WNT4, PTGES2, NOTCH4, GATA5, TBX21 |
positive regulation of transforming growth factor beta production | biological_process | PTGS2, LGALS9 |
positive regulation of transforming growth factor beta receptor signaling pathway | biological_process | TGFB1I1, THBS1, SMAD4, ADAM17 |
positive regulation of transforming growth factor beta1 production | biological_process | THBS1, FOXP3, CX3CL1 |
positive regulation of transforming growth factor beta2 production | biological_process | ATF2 |
positive regulation of transforming growth factor beta3 production | biological_process | SMAD3 |
positive regulation of translation | biological_process | MAPK1, ITGA2, MTOR, ERBB2, THBS1, IL6, ELAVL1, UCN |
positive regulation of translational initiation | biological_process | CCL5 |
positive regulation of translational initiation by iron | biological_process | TNF |
positive regulation of transmission of nerve impulse | biological_process | ITGA2, IL6 |
positive regulation of transporter activity | biological_process | PON1, SGK1 |
positive regulation of triglyceride biosynthetic process | biological_process | SCARB1 |
positive regulation of triglyceride catabolic process | biological_process | APOA1 |
positive regulation of trophectodermal cell proliferation | biological_process | IGF1 |
positive regulation of trophoblast cell migration | biological_process | C1QBP |
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production | biological_process | IFNG, ADAM8 |
positive regulation of tumor necrosis factor biosynthetic process | biological_process | CCR2, HSPB1, TLR4, THBS1 |
positive regulation of tumor necrosis factor production | biological_process | HMGB1, CLU, PIK3R1, CD36, IL12B, CCL3, CCL2, HLA-E, FCER1G, CCR2, IFNG, TLR2, TLR4, TLR3, HDAC2, TLR9, NOD2, CCL19, NOD1, TWIST1, IL23A |
positive regulation of tumor necrosis factor secretion | biological_process | LGALS9 |
positive regulation of type 2 immune response | biological_process | IDO1, IL33, CD74, NOD2 |
positive regulation of type B pancreatic cell apoptotic process | biological_process | IL6, AGER |
positive regulation of type I hypersensitivity | biological_process | FCER1G |
positive regulation of type I interferon production | biological_process | CTNNB1, NFKB1, STAT6, TLR3, RELA, NFKB2, PTPN22 |
positive regulation of type I interferon-mediated signaling pathway | biological_process | WNT5A |
positive regulation of type IIa hypersensitivity | biological_process | FCER1G, C3 |
positive regulation of type III hypersensitivity | biological_process | FCER1G |
positive regulation of type III interferon production | biological_process | TLR3 |
positive regulation of tyrosine 3-monooxygenase activity | biological_process | PARK7 |
positive regulation of tyrosine phosphorylation of STAT protein | biological_process | CCL5, FLT3 |
positive regulation of tyrosine phosphorylation of Stat1 protein | biological_process | TNFRSF1A, KIT, CD40, IL6ST, LIF, IFNG, HPX |
positive regulation of tyrosine phosphorylation of Stat3 protein | biological_process | VEGFA, STAT3, KIT, IL12B, LEP, PTGER4, IL6R, IL6ST, CNTF, IL15, LIF, SOCS3, IL6, CSF1R, HDAC2, HES5, IL18, IL24, IL23A |
positive regulation of tyrosine phosphorylation of Stat4 protein | biological_process | IL12B, IL12A, IL23A |
positive regulation of tyrosine phosphorylation of Stat5 protein | biological_process | KIT, IL12B, IGF1, FYN, CSF2, IL4, IL23A, IL2 |
positive regulation of tyrosine phosphorylation of Stat6 protein | biological_process | IL13 |
positive regulation of ubiquitin protein ligase activity | biological_process | PTEN, PLK1 |
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | biological_process | CCNB1, PSMD9, PSMD10, PLK1 |
positive regulation of ubiquitin-protein transferase activity | biological_process | PLK1 |
positive regulation of ureteric bud formation | biological_process | GATA3 |
positive regulation of urine volume | biological_process | PTGER4, DRD2, EDN1 |
positive regulation of uterine smooth muscle contraction | biological_process | TACR2, TACR1, OXTR, GPER1 |
positive regulation of vascular endothelial growth factor production | biological_process | BRCA1, FLT4, IL6ST, ARNT, PTGS2, TGFB1, IL1A, C3, IL1B, C5, HPSE, HIF1A, CYP1B1, NODAL |
positive regulation of vascular endothelial growth factor receptor signaling pathway | biological_process | VEGFA, FLT1, ARNT, ITGB3, PRKCB, IL1B, HIF1A |
positive regulation of vascular permeability | biological_process | VEGFA, TACR2, TACR1, TGFB1, PTP4A3, UCN |
positive regulation of vascular smooth muscle cell differentiation | biological_process | KIT |
positive regulation of vasculogenesis | biological_process | KDR, ADM |
positive regulation of vasoconstriction | biological_process | F2R, GJA1, AKT1, SHC1, TACR1, PTGS1, OXTR, PTGS2, PTGER3, FGA, ICAM1 |
positive regulation of vasodilation | biological_process | NOS2, GJA1, AGTR2, HMOX1, NOS3, ADM, F2RL1, ESR2, KAT2B, GPER1, UCN |
positive regulation of vesicle fusion | biological_process | PLA2G4A, ANXA1, ANXA2 |
positive regulation of viral entry into host cell | biological_process | LGALS1, LGALS9 |
positive regulation of viral genome replication | biological_process | CCL5, NOTCH1, NR5A2 |
positive regulation of viral transcription | biological_process | NOTCH1 |
positive regulation of vitamin D 24-hydroxylase activity | biological_process | VDR |
positive regulation of vitamin D biosynthetic process | biological_process | IFNG, TNF |
positive regulation of voltage-gated chloride channel activity | biological_process | CFTR |
positive regulation of Wnt signaling pathway | biological_process | FGFR2, TERT, TLR2, MBD2 |
positive regulation of wound healing | biological_process | HMGB1, PTGER4, ANXA1 |
positive regulation of xenophagy | biological_process | NOD1 |
positive T cell selection | biological_process | BRAF |
positive thymic T cell selection | biological_process | CD74 |
post-anal tail morphogenesis | biological_process | WNT5A, TP63 |
post-embryonic animal organ morphogenesis | biological_process | BCL2L11 |
post-embryonic camera-type eye development | biological_process | VEGFA |
post-embryonic camera-type eye morphogenesis | biological_process | BAX |
post-embryonic development | biological_process | BCL2, GATA3, BMP4, FGFR2, IGF2R, MTOR, CYP1A2, BCL2L11, PRDM1, BAX, SMAD2, SEMA3C, TET2 |
post-Golgi vesicle-mediated transport | biological_process | PLCB3 |
post-translational protein modification | biological_process | STS, ARSH |
posterior mesonephric tubule development | biological_process | WT1 |
postreplication repair | biological_process | MSH2, BRCA1 |
postsynaptic density assembly | biological_process | PTEN |
potassium ion transport | biological_process | CDKN1B |
pre-B cell allelic exclusion | biological_process | ATM |
pre-miRNA processing | biological_process | DICER1 |
preantral ovarian follicle growth | biological_process | AMH |
prepulse inhibition | biological_process | DRD2, PTEN |
presynaptic active zone assembly | biological_process | PCDH17 |
presynaptic membrane assembly | biological_process | PTEN |
primary miRNA processing | biological_process | SMAD3, SMAD2 |
primary ovarian follicle growth | biological_process | FSHR |
primary sex determination | biological_process | NR5A1 |
primitive erythrocyte differentiation | biological_process | VEGFA |
primitive streak formation | biological_process | WNT5A, NODAL |
pro-B cell differentiation | biological_process | FLT3 |
pro-T cell differentiation | biological_process | GATA3 |
production of miRNAs involved in gene silencing by miRNA | biological_process | DICER1 |
production of siRNA involved in RNA interference | biological_process | TERT, DICER1 |
progesterone biosynthetic process | biological_process | ADM, STAR, FSHB, LHB |
progesterone metabolic process | biological_process | AKR1C3, AKR1C2, CYP17A1, AKR1C1, SRD5A1 |
progesterone receptor signaling pathway | biological_process | SRC |
progesterone secretion | biological_process | INHBA |
programmed cell death | biological_process | TP53 |
programmed necrotic cell death | biological_process | CASP1 |
prolactin secretion | biological_process | TACR2, ANXA1 |
prolactin signaling pathway | biological_process | PRLR |
pronephric field specification | biological_process | PAX2 |
pronephric nephron tubule development | biological_process | HNF1B |
pronephros development | biological_process | HNF1B, PAX2 |
prostaglandin biosynthetic process | biological_process | PTGDS, MIF, PTGS1, PTGS2, PTGES, CD74, EDN1, PTGES2 |
prostaglandin metabolic process | biological_process | PTGDS, TNFRSF1A, HPGD, PTGS1, PTGS2, AKR1C3, AKR1C2, PTGES, PTGES2 |
prostaglandin receptor internalization | biological_process | PTGER3 |
prostaglandin secretion | biological_process | NOS2, LEP, ABCC4 |
prostaglandin transport | biological_process | SLCO2A1 |
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | biological_process | FGFR2, ESR1 |
prostate epithelial cord elongation | biological_process | FGFR2, ESR1 |
prostate gland development | biological_process | WNT5A, AR, ANXA1, FKBP4, ESR2, TP63 |
prostate gland epithelium morphogenesis | biological_process | NOTCH1, TNC |
prostate gland growth | biological_process | CYP19A1, PRLR, PSAP, PTEN |
prostate gland morphogenesis | biological_process | BMP4, FGFR2 |
prostatic bud formation | biological_process | TP63 |
proteasomal ubiquitin-independent protein catabolic process | biological_process | NFE2L2 |
proteasome regulatory particle assembly | biological_process | PSMD9, PSMD10 |
proteasome-mediated ubiquitin-dependent protein catabolic process | biological_process | GSK3B, CTNNB1, UCHL1, PSMD9, CLOCK, TP53, PSMD10, NFE2L2, SIRT1 |
protection from natural killer cell mediated cytotoxicity | biological_process | HLA-E, HLA-B |
protein acetylation | biological_process | FOXO1, KAT2B |
protein ADP-ribosylation | biological_process | SIRT1 |
protein autophosphorylation | biological_process | GSK3B, FGFR1, SRC, FGFR2, KIT, AKT1, KDR, FLT4, PDGFRA, JAK1, FLT1, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, IGF1R, ERBB2, FYN, CSF1R, PTK2, NTRK2, TYRO3, TEK, PAK1, ATM, DAPK1, PIM2 |
protein autoubiquitination | biological_process | BRCA1 |
protein catabolic process | biological_process | AKT1, MTOR, CTSD |
protein complex assembly | biological_process | CCNB1, HMGA1, CD40, FAS, IL2RB, FGA, TP53, CD74, HES5, KIFAP3, IL1RAP, LAMC1 |
protein complex localization | biological_process | BIRC5, FKBP4 |
protein deacetylation | biological_process | HDAC1, SIRT1 |
protein deamination | biological_process | LOXL1 |
protein deglycosylation | biological_process | PARK7 |
protein deneddylation | biological_process | COPS5 |
protein dephosphorylation | biological_process | BCL2, ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR, ILKAP |
protein destabilization | biological_process | SRC, ID1, PLK1, SIRT1, CDKN2A |
protein deubiquitination | biological_process | UCHL1, COPS5 |
protein export from nucleus | biological_process | GSK3B, TGFB1, CSE1L |
protein folding | biological_process | HSPD1, TXN, HSP90AA1, CRYAB, APCS, FKBP4, FKBP5 |
protein glycosylation | biological_process | DAD1, GBGT1 |
protein heterooligomerization | biological_process | CTNNB1, BRAF, CTNNA1, CLDN3, Sep-09 |
protein heterotetramerization | biological_process | INSR, ANXA2, HIST3H3 |
protein heterotrimerization | biological_process | ADIPOQ |
protein homooligomerization | biological_process | ANXA5, SLC6A4, HMOX1, FAS, CRYAB, CLDN3, BAX, ADIPOQ, AKR1C1, P2RX3, OLFM4 |
protein homotetramerization | biological_process | GPX3, CAT, TP63 |
protein homotrimerization | biological_process | MIF |
protein import | biological_process | CLU, APOE |
protein import into mitochondrial outer membrane | biological_process | HSPA4, HSP90AA1 |
protein import into nucleus | biological_process | STAT3, CSE1L, IPO13 |
protein import into nucleus, translocation | biological_process | BCL6, AKT1, AKR1C3, IFNG, TGFB1, TNF |
protein insertion into membrane | biological_process | EGFR |
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological_process | BCL2L11, BAX |
protein K6-linked ubiquitination | biological_process | BRCA1 |
protein K63-linked ubiquitination | biological_process | CDKN2A |
protein kinase B signaling | biological_process | CCL5, AKT1, CCL3, CD40, AXL, CCL2, PIK3CA, IGF1, TGFB1, TNF, IL1B, PTEN, GAS6, TYRO3, PAX2 |
protein kinase C deactivation | biological_process | EDN1 |
protein kinase C-activating G-protein coupled receptor signaling pathway | biological_process | F2R, EDNRA, EDN1, IL2, CRHR2 |
protein localization | biological_process | BCL6, DRD2, TP53, KIFAP3 |
protein localization to bicellular tight junction | biological_process | ACTN4 |
protein localization to cell surface | biological_process | CTNNB1, ANGPT1 |
protein localization to centrosome | biological_process | AURKA |
protein localization to chromatin | biological_process | ESR1, PLK1, EZH2 |
protein localization to chromosome, centromeric region | biological_process | RB1 |
protein localization to cytoplasmic stress granule | biological_process | TIA1, YBX1 |
protein localization to early endosome | biological_process | NRP1 |
protein localization to microtubule | biological_process | GSK3B |
protein localization to nucleus | biological_process | BMP4 |
protein localization to plasma membrane | biological_process | CDH1, DPP6, FCER1G, RAC1, ADIPOQ |
protein maturation | biological_process | HSPD1 |
protein N-linked glycosylation via asparagine | biological_process | DAD1 |
protein O-linked fucosylation | biological_process | THBS1 |
protein O-linked glycosylation | biological_process | TET3, TET2, TET1 |
protein oligomerization | biological_process | GJA1, SLC6A4, AR, LIPC, BAX, TEK, STOML2, NOD2, NOD1 |
protein oxidation | biological_process | APOA1, APOA2, GPX1 |
protein peptidyl-prolyl isomerization | biological_process | FKBP4, FKBP5 |
protein phosphorylation | biological_process | GSK3B, FGFR1, SRC, CCND1, MET, WNT5A, MAPK1, FGFR2, IGFBP3, PIK3R1, KIT, AKT1, CCNB1, ERBB3, KDR, RASSF2, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, CCL2, PIK3CA, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, TGFB1, MAP3K7, IGF1R, PRKCB, BIRC5, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, CTSG, RUNX3, PLK1, TGFB2, PTK2, NTRK2, GAS6, TYRO3, TEK, HSF1, PAK1, SMAD2, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2, KSR1, CCL11 |
protein polymerization | biological_process | FGA |
protein polyubiquitination | biological_process | BCL2, PSMD9, PSMD10, TRIM36, CDKN2A, BLMH |
protein processing | biological_process | CASP1, CASP3, CMA1, CTSG, PCSK5 |
protein refolding | biological_process | HSPD1, HSPA6, HSP90AA1 |
protein repair | biological_process | TXN |
protein secretion | biological_process | SNCG |
protein stabilization | biological_process | HSPD1, CLU, PIK3R1, RASSF2, CDKN1A, CHEK2, IGF1, HSP90AA1, APOA1, SMAD7, PTEN, PARK7, PIM2, CDKN2A, NAA15 |
protein sumoylation | biological_process | PCNA, BRCA1, TP53, BIRC5, XRCC4, CDKN2A, PIAS3 |
protein targeting to plasma membrane | biological_process | BSG, ANXA2, GAS6 |
protein tetramerization | biological_process | CCL5, HLA-DRB1, IGF1R, TP53, CAT, TP63 |
protein transmembrane transport | biological_process | AZGP1, MCL1 |
protein transport | biological_process | PIK3R1, ACTN4, CCDC22, S100A13, CSE1L, IPO13 |
protein transport within lipid bilayer | biological_process | ITGB1 |
protein ubiquitination | biological_process | AKT1, BRCA1, BIRC5, SOCS3, CDC42, PLK1, NFE2L2, SIRT1 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological_process | CCNB1, AURKA, PLK1 |
protein unfolding | biological_process | HSP90AA1 |
protein-DNA complex assembly | biological_process | HNF1B |
proteoglycan biosynthetic process | biological_process | IGF1, BMPR1B, XYLT2 |
proteoglycan metabolic process | biological_process | HPSE |
proteolysis | biological_process | MME, MMP13, DPP6, MMP9, CASP1, MBL2, ACE, CASP3, UCHL1, HGF, MMP7, MMP10, C4A, MMP14, CMA1, MMP11, MMP12, PLAT, LTF, C3, CAPN5, CTSB, PLAU, MMP1, CTSD, KLK3, MMP2, MMP3, CTSG, COPS5, PARK7, ADAM17, PCSK5, ADAM8, ADAM22, BLMH, TPSAB1, FOLH1, PAPPA, WFDC2, IHH, HTRA1, CPB2, MMP24, TPSB2, MST1 |
proteolysis in other organism | biological_process | MAP2K7 |
proteolysis involved in cellular protein catabolic process | biological_process | CTSB |
proton transport | biological_process | ATP5A1, ATP5B |
proximal/distal pattern formation | biological_process | CTNNB1, HOXA10, HOXA11, GREM1, TP63 |
pulmonary artery endothelial tube morphogenesis | biological_process | BMP4 |
pulmonary artery morphogenesis | biological_process | JAG1 |
pulmonary myocardium development | biological_process | SEMA3C |
pulmonary valve morphogenesis | biological_process | NOTCH1, HEY1, JAG1 |
purine nucleobase metabolic process | biological_process | IL1B |
purine nucleoside metabolic process | biological_process | PNP |
purine nucleotide catabolic process | biological_process | XDH, PNP, GPX1, CAT |
purine nucleotide metabolic process | biological_process | NME1, FHIT |
purine nucleotide salvage | biological_process | ADA |
purine ribonucleoside monophosphate biosynthetic process | biological_process | ADA |
purine-containing compound salvage | biological_process | PNP, ADA |
purinergic nucleotide receptor signaling pathway | biological_process | P2RX3 |
pyramidal neuron development | biological_process | FGFR2, ATP7A |
pyrimidine dimer repair by nucleotide-excision repair | biological_process | SIRT1 |
pyrimidine nucleobase metabolic process | biological_process | TYMP |
pyrimidine nucleoside catabolic process | biological_process | TYMP |
pyrimidine nucleoside metabolic process | biological_process | TYMP |
pyrimidine nucleoside salvage | biological_process | TYMP |
pyrimidine nucleotide metabolic process | biological_process | NME1, TYMP |
pyroptosis | biological_process | CASP1 |
pyruvate metabolic process | biological_process | BSG |
Rac protein signal transduction | biological_process | AIF1 |
radial glial cell differentiation | biological_process | STAT3 |
radial pattern formation | biological_process | NR2F2 |
Ras protein signal transduction | biological_process | FGF2, DNMT1, SHC1, CDKN1A, CDKN2A, IGF1, JUN, TP53, RB1, NRAS, KRAS, PARK7, KSR1 |
re-entry into mitotic cell cycle | biological_process | GSK3B, CCND1 |
reactive oxygen species metabolic process | biological_process | BCL2, NDUFS1, SOD1, CYR61, PAX2 |
receptor biosynthetic process | biological_process | IL10, TNF |
receptor catabolic process | biological_process | TGFB1 |
receptor clustering | biological_process | ITGB2 |
receptor internalization | biological_process | CD36, CXCL8, CXCR1, CXCR2, FCER1G, ADM, PTGER3, ITGB1, ITGB2, LILRB1 |
receptor-mediated endocytosis | biological_process | CETP, FOLR1, IGF2R, CD36, SPARC, SAA1, MRC1, HSP90AA1, APOA1, APOE, HP, HPX, LOXL4, SCARB1, CXCL16 |
receptor-mediated virion attachment to host cell | biological_process | ICAM1, GAS6 |
reciprocal meiotic recombination | biological_process | MSH2, MSH6, MLH1, XRCC3, ATM |
recognition of apoptotic cell | biological_process | SCARB1 |
regulated exocytosis | biological_process | CRHBP |
regulation of acrosome reaction | biological_process | SPINK1 |
regulation of actin cytoskeleton organization | biological_process | CRK, MTOR, PDGFA, TGFB2, PAK1, RHOA |
regulation of actin cytoskeleton reorganization | biological_process | PDGFRA, TGFB1, CSF1R |
regulation of actin filament polymerization | biological_process | LATS1 |
regulation of actin polymerization or depolymerization | biological_process | CXCL12 |
regulation of activated T cell proliferation | biological_process | IDO1 |
regulation of activin receptor signaling pathway | biological_process | SMAD7 |
regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway | biological_process | CRHR1 |
regulation of aerobic respiration | biological_process | HIF1A |
regulation of androgen receptor signaling pathway | biological_process | PARK7 |
regulation of angiogenesis | biological_process | FGF2, LEP, CTNNB1, ID1, HMOX1, EFNA1, ERBB2, CXCL13, KRT1, IL6, PROK1 |
regulation of angiotensin metabolic process | biological_process | ACE |
regulation of animal organ formation | biological_process | WT1 |
regulation of anion transmembrane transport | biological_process | CLCN3 |
regulation of anion transport | biological_process | CA2, STC1 |
regulation of apoptotic cell clearance | biological_process | ITGAV |
regulation of apoptotic DNA fragmentation | biological_process | CDKN2A |
regulation of apoptotic process | biological_process | BCL2, EGR1, BCL6, TNFRSF1A, IGF2R, IGFBP3, CTNNB1, BRCA1, CASP1, NME1, TNFRSF1B, AGTR2, LGALS1, FAS, BMP6, FLT3, ESR1, TGFB1, ACTN4, INHA, TP53, BIRC5, FYN, SGK1, TNFRSF11B, MSTN, BCL2L11, GDF9, CTSB, TNFRSF21, IL6, TGFB2, BCL2L1, BAX, NOD2, MCL1, ATM, NOD1, DAPK1, TP63, OLFM4, GDF15, SRA1 |
regulation of appetite | biological_process | NPY |
regulation of asymmetric cell division | biological_process | POU5F1 |
regulation of atrial cardiac muscle cell membrane depolarization | biological_process | GJA1 |
regulation of attachment of spindle microtubules to kinetochore | biological_process | CDC42 |
regulation of auditory receptor cell differentiation | biological_process | NOTCH1, HES5 |
regulation of autophagy | biological_process | BCL2, HMGB1, CASP1, HSPB1, PSAP, ATM, DAPK1 |
regulation of axon diameter | biological_process | WNT7A |
regulation of axon extension | biological_process | GSK3B, APOE, DPYSL2, OLFM1 |
regulation of axon extension involved in axon guidance | biological_process | NRP1, SEMA3A |
regulation of axon regeneration | biological_process | BRAF, PTEN |
regulation of axonogenesis | biological_process | GSK3B, EFNA1, WNT7A |
regulation of B cell apoptotic process | biological_process | PTEN |
regulation of B cell proliferation | biological_process | AHR |
regulation of B cell receptor signaling pathway | biological_process | PTPN22 |
regulation of behavior | biological_process | MDK |
regulation of beta-amyloid clearance | biological_process | CLU, APOE |
regulation of bicellular tight junction assembly | biological_process | GJA1, SNAI1 |
regulation of bile acid biosynthetic process | biological_process | SIRT1 |
regulation of binding | biological_process | TGFB1, SMAD3, SMAD2, SMAD4 |
regulation of blood coagulation | biological_process | F2R, F2RL1 |
regulation of blood pressure | biological_process | PPARG, LEP, ACE, AGTR2, EDNRA, HMOX1, TACR1, PTGS1, NOS3, PTGS2, SOD1, SGK1, EDN1, NRG1, NPY |
regulation of blood vessel diameter by renin-angiotensin | biological_process | AGTR1 |
regulation of blood vessel endothelial cell migration | biological_process | EFNA1 |
regulation of blood vessel remodeling | biological_process | FLT4, TGFB1 |
regulation of blood vessel size | biological_process | GCLC, NOS3, EDN1 |
regulation of blood volume by renal aldosterone | biological_process | HSD11B2 |
regulation of BMP signaling pathway | biological_process | ITGA3 |
regulation of bone mineralization | biological_process | GJA1, AHSG, TWIST1 |
regulation of bone remodeling | biological_process | GJA1, LEP, LEPR |
regulation of bone resorption | biological_process | SRC, ITGB3, CSF1R, IL20RA |
regulation of branch elongation involved in ureteric bud branching | biological_process | HNF1B |
regulation of branching involved in mammary gland duct morphogenesis | biological_process | WNT5A, TGFB1 |
regulation of branching involved in prostate gland morphogenesis | biological_process | BMP4, FGFR2, ESR1 |
regulation of branching involved in salivary gland morphogenesis | biological_process | TNF |
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling | biological_process | PDGFA |
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling | biological_process | NTN4 |
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling | biological_process | FGFR1, HGF |
regulation of brown fat cell differentiation | biological_process | LEP, MTOR, SIRT1 |
regulation of calcidiol 1-monooxygenase activity | biological_process | VDR |
regulation of calcium ion import | biological_process | CTNNB1, EGF |
regulation of calcium ion transport | biological_process | BCL2, GJA1, CXCL12, IGF1, CXCR4 |
regulation of cAMP metabolic process | biological_process | DRD2 |
regulation of cAMP-dependent protein kinase activity | biological_process | MST1 |
regulation of canonical Wnt signaling pathway | biological_process | YAP1, FOLR1 |
regulation of carbohydrate metabolic process | biological_process | MTOR |
regulation of carbohydrate utilization | biological_process | MTOR |
regulation of cardiac muscle cell contraction | biological_process | STC1 |
regulation of cardiac muscle contraction | biological_process | SMAD7 |
regulation of cardioblast proliferation | biological_process | NOTCH1 |
regulation of cartilage development | biological_process | BMP4, TGFB1 |
regulation of catalytic activity | biological_process | BCL2, HSP90AA1, SGK1, CTSB, HIF1A, DNMT3L |
regulation of caveolin-mediated endocytosis | biological_process | SRC |
regulation of CD4-positive, alpha-beta T cell activation | biological_process | AGER |
regulation of CD4-positive, alpha-beta T cell differentiation | biological_process | GATA3 |
regulation of Cdc42 protein signal transduction | biological_process | APOA1, APOE |
regulation of cell adhesion | biological_process | CXCL8, ENG, PRLR, LAMA1, LAMA5, ICAM1, IL18 |
regulation of cell adhesion mediated by integrin | biological_process | EFNA1, PLAU, PTK2 |
regulation of cell cycle | biological_process | BCL2, SRC, CCND1, STAT3, LEP, CCNB1, CDKN1A, ITGB1, JUN, INHA, SGK1, RB1, COPS5, PTEN, PLK1, BAX, PLCB1, ATM, TRIM36 |
regulation of cell cycle checkpoint | biological_process | AKT1 |
regulation of cell cycle G2/M phase transition | biological_process | TP53, PLK1 |
regulation of cell cycle process | biological_process | HMGA2 |
regulation of cell death | biological_process | JUN, CRYAB |
regulation of cell differentiation | biological_process | FGFR1, BMP4, CTNNB1, LIF, SOCS3, SPRY2, RUNX3, NRG1, HES5, IHH, SPOCK2, NANOG |
regulation of cell fate commitment | biological_process | BMP4, FGFR2 |
regulation of cell growth | biological_process | IGFBP2, IGFBP3, AGTR1, IGFBP5, IGFBP1, IGFBP4, SGK1, CYR61, IGFBP7, HTRA1 |
regulation of cell migration | biological_process | AKT1, NOTCH1, LAMA1, MMP10, ITGB3, TGFB1, SGK1, LAMA5, RAC1, CXCR4, JAG1, SST, RHOA |
regulation of cell morphogenesis | biological_process | CFL1, SPARC, RAC1 |
regulation of cell motility | biological_process | ERBB3, EGFR, ERBB2, EGF, NRG1, RHOA |
regulation of cell projection assembly | biological_process | SRC, CCL19 |
regulation of cell proliferation | biological_process | FGFR1, SRC, YAP1, BCL6, NOS2, DNMT1, PLA2G4A, TNFRSF1A, KIT, MIF, SHC1, CTNNB1, BRCA1, ERBB3, CDKN1B, NOTCH1, PLCD1, TNFRSF1B, CD40, BRAF, CTNNA1, AGTR1, ENG, JAK1, SPARC, TYK2, FAS, STAT6, CXCL2, PTGS1, TNC, PTGS2, PTGER2, IGF1, EGFR, JUN, TGFB1, ANXA1, LGR5, INHA, TNF, CXCL10, FYN, SGK1, TNFRSF11B, NR5A2, WNT7A, LAMA5, SPRY2, CXCL13, TNFRSF21, PRDM1, PLAU, CSF2, IL6, PTK2, HIF1A, FOXO1, GHRL, EZH2, SIRT1, SMAD4, JAG1, CXCL6, PLCD3, MBD2 |
regulation of cell shape | biological_process | VEGFA, KIT, CCL3, KDR, CCL2, PTN, FN1, ANXA1, FYN, ITGB2, ICAM1, IL6, CSF1R, PTK2, S100A13, CCL7, CCL11 |
regulation of cell size | biological_process | RAC1 |
regulation of cell-cell adhesion | biological_process | SRC, ADAM8, WNT4 |
regulation of cell-cell adhesion mediated by integrin | biological_process | ADA |
regulation of cell-matrix adhesion | biological_process | BCL2 |
regulation of cellular amino acid metabolic process | biological_process | PSMD9, PSMD10 |
regulation of cellular component size | biological_process | PTEN |
regulation of cellular extravasation | biological_process | SELP |
regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter | biological_process | PPARA |
regulation of cellular localization | biological_process | PTEN |
regulation of cellular protein localization | biological_process | WNT5A |
regulation of cellular respiration | biological_process | NOS2, PIK3CA |
regulation of cellular response to drug | biological_process | HMGA2 |
regulation of cellular response to heat | biological_process | GSK3B, MAPK1, MTOR, HSP90AA1, CRYAB, HSF1, FKBP4, SIRT1, ATM |
regulation of cellular response to hypoxia | biological_process | HIF1A |
regulation of cellular response to X-ray | biological_process | GATA3 |
regulation of centriole-centriole cohesion | biological_process | CTNNB1 |
regulation of centromere complex assembly | biological_process | RB1 |
regulation of centromeric sister chromatid cohesion | biological_process | CTNNB1 |
regulation of centrosome cycle | biological_process | AURKA |
regulation of centrosome duplication | biological_process | XRCC3 |
regulation of cGMP metabolic process | biological_process | VEGFA, THBS1 |
regulation of chemotaxis | biological_process | PDGFRA, CXCR4 |
regulation of chloride transport | biological_process | CA2 |
regulation of cholesterol efflux | biological_process | CETP |
regulation of cholesterol transporter activity | biological_process | PPARG |
regulation of chondrocyte differentiation | biological_process | HOXA11, MAF |
regulation of chromosome condensation | biological_process | CCNB1 |
regulation of chronic inflammatory response | biological_process | CCL5 |
regulation of circadian rhythm | biological_process | PPARG, PPARA, EZH2, ID2, KLF10 |
regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | IL6 |
regulation of circadian sleep/wake cycle, sleep | biological_process | PTGDS, ADA |
regulation of circadian sleep/wake cycle, wakefulness | biological_process | PTGER4, PTGER3 |
regulation of cohesin loading | biological_process | RB1 |
regulation of collagen catabolic process | biological_process | ITGB1 |
regulation of complement activation | biological_process | C4A, C3, C5, C4BPA, C1QBP |
regulation of complement-dependent cytotoxicity | biological_process | IL10, IL11, TGFB2 |
regulation of core promoter binding | biological_process | CTNNB1 |
regulation of corticosterone secretion | biological_process | CRHR1 |
regulation of corticotropin secretion | biological_process | CRHBP |
regulation of cyclin-dependent protein serine/threonine kinase activity | biological_process | CDKN1B, CDKN1A, DIRAS3, PTEN |
regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | FAS, SOX2, NGF, BAX, TP63 |
regulation of cytokine biosynthetic process | biological_process | GATA3, IL12B |
regulation of cytokine production | biological_process | LTF, CD83 |
regulation of cytokine production involved in inflammatory response | biological_process | NOS2, LEP |
regulation of cytokine secretion | biological_process | TLR2, TLR4, TLR9 |
regulation of cytokinesis | biological_process | BRCA2, AURKA |
regulation of cytoskeleton organization | biological_process | MAPK1, STMN1, PTK2 |
regulation of cytosolic calcium ion concentration | biological_process | GPER1 |
regulation of defense response to bacterium | biological_process | FOXP1 |
regulation of defense response to virus | biological_process | IL27 |
regulation of defense response to virus by host | biological_process | IL15 |
regulation of defense response to virus by virus | biological_process | CD4, FYN, RAC1 |
regulation of dendrite development | biological_process | NTRK2 |
regulation of dendrite morphogenesis | biological_process | GSK3B |
regulation of dendritic cell cytokine production | biological_process | TLR4, TLR3 |
regulation of dendritic cell dendrite assembly | biological_process | CCR7 |
regulation of dendritic cell differentiation | biological_process | HLA-B |
regulation of dendritic spine morphogenesis | biological_process | CFL1 |
regulation of developmental pigmentation | biological_process | BCL2, KIT, BCL2L11 |
regulation of developmental process | biological_process | NOTCH1 |
regulation of digestive system process | biological_process | OXTR |
regulation of DNA binding | biological_process | TGFB1 |
regulation of DNA biosynthetic process | biological_process | CDKN1A, PDGFA |
regulation of DNA methylation | biological_process | BRCA1 |
regulation of DNA replication | biological_process | PCNA, EHMT2 |
regulation of dopamine secretion | biological_process | DRD2, SNCG |
regulation of dopamine uptake involved in synaptic transmission | biological_process | DRD2 |
regulation of dopaminergic neuron differentiation | biological_process | DKK1 |
regulation of early endosome to late endosome transport | biological_process | SRC, MAPK1 |
regulation of embryonic development | biological_process | LAMA1, INSR, LAMA5, NFE2L2 |
regulation of endodeoxyribonuclease activity | biological_process | SIRT1 |
regulation of endodermal cell fate specification | biological_process | HNF1B, DKK1 |
regulation of endothelial cell apoptotic process | biological_process | TEK |
regulation of endothelial cell chemotaxis to fibroblast growth factor | biological_process | FGF2, FGF1 |
regulation of endothelial cell migration | biological_process | PTK2 |
regulation of endothelial cell proliferation | biological_process | LEP, ANGPT1 |
regulation of endothelial tube morphogenesis | biological_process | FGF1, CXCL10, FOXP1 |
regulation of energy homeostasis | biological_process | CD36, LEPR, FOXO1 |
regulation of engulfment of apoptotic cell | biological_process | ALOX15 |
regulation of epidermal cell division | biological_process | TP63 |
regulation of epidermal growth factor-activated receptor activity | biological_process | SHC1 |
regulation of epithelial cell differentiation | biological_process | XDH, CTNNB1, PRLR |
regulation of epithelial cell migration | biological_process | SRC, PTK2 |
regulation of epithelial cell proliferation | biological_process | NOTCH1, EDNRA, SMAD3, HES5 |
regulation of epithelial cell proliferation involved in prostate gland development | biological_process | NOTCH1 |
regulation of epithelial to mesenchymal transition | biological_process | GREM1, SMAD7 |
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological_process | TGFB1 |
regulation of ERK1 and ERK2 cascade | biological_process | BMP4, FGFR2, GSTP1, FN1, ERBB2, CYR61, CRHR2 |
regulation of establishment of cell polarity | biological_process | GATA3 |
regulation of establishment of endothelial barrier | biological_process | TNFRSF1A, TNF, IL1B |
regulation of establishment of protein localization to plasma membrane | biological_process | PIK3R1, AR |
regulation of establishment or maintenance of cell polarity | biological_process | TEK |
regulation of euchromatin binding | biological_process | CTNNB1 |
regulation of extracellular matrix assembly | biological_process | NOTCH1 |
regulation of extracellular matrix organization | biological_process | TGFB2 |
regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological_process | FGFR1 |
regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological_process | LGALS3, TNFSF10, FASLG, FAS |
regulation of fat cell differentiation | biological_process | PPARG, LEP |
regulation of fatty acid beta-oxidation | biological_process | MTOR |
regulation of fatty acid metabolic process | biological_process | PPARA |
regulation of feeding behavior | biological_process | STAT3, LEPR |
regulation of female gonad development | biological_process | INSR |
regulation of fertilization | biological_process | PLCB1 |
regulation of fibroblast growth factor receptor signaling pathway | biological_process | FGFR2 |
regulation of fibroblast migration | biological_process | SDC4, RAC1 |
regulation of fibroblast proliferation | biological_process | CTNNB1 |
regulation of filopodium assembly | biological_process | CDC42 |
regulation of flagellated sperm motility | biological_process | ANXA5 |
regulation of focal adhesion assembly | biological_process | GREM1, PTK2 |
regulation of follicle-stimulating hormone secretion | biological_process | INHBA |
regulation of forebrain neuron differentiation | biological_process | GATA2 |
regulation of G-protein coupled receptor protein signaling pathway | biological_process | ITGB1, PLCB1 |
regulation of G1/S transition of mitotic cell cycle | biological_process | CCND1, ID2 |
regulation of G2/M transition of mitotic cell cycle | biological_process | CDKN2A |
regulation of gastric acid secretion | biological_process | SGK1 |
regulation of gastrulation | biological_process | NODAL |
regulation of gene expression | biological_process | BCL2, FGFR1, BMP4, DNMT1, IL10, CTNNB1, AHR, NOTCH1, FAS, HOXA10, PIK3CA, HOXA11, SOX2, IGF1, TGFB1, APOE, MYC, CYP1A2, CSF2, DNMT3A, HIF1A, PPARA, POU5F1, EZH2, DNMT3B, EMX2, GATA6, NANOG |
regulation of gene expression by genetic imprinting | biological_process | GSK3B, BRCA1, DIRAS3, IGF2, DNMT3A, DNMT3L |
regulation of gene expression, epigenetic | biological_process | GPX1 |
regulation of genetic imprinting | biological_process | PIK3CA |
regulation of germinal center formation | biological_process | BCL6 |
regulation of gliogenesis | biological_process | EZH2 |
regulation of glomerular mesangial cell proliferation | biological_process | PDGFA |
regulation of gluconeogenesis | biological_process | LEP |
regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter | biological_process | FOXO1 |
regulation of glucose metabolic process | biological_process | IGFBP3, IGFBP5, IGFBP4, ADIPOQ, SIRT1, ADIPOR1 |
regulation of glycogen biosynthetic process | biological_process | AKT1, MTOR |
regulation of glycolytic process | biological_process | HIF1A |
regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter | biological_process | PPARA |
regulation of glycoprotein biosynthetic process | biological_process | BCL2 |
regulation of Golgi inheritance | biological_process | MAPK1 |
regulation of Golgi organization | biological_process | STX5 |
regulation of granulocyte macrophage colony-stimulating factor biosynthetic process | biological_process | IL17F |
regulation of growth | biological_process | HMGA2, IGFBP2, IGFBP3, SHC1, IGFBP5, IGFBP4, IFNG, SOCS3, GAS6 |
regulation of GTPase activity | biological_process | CRK, BCL6, MTOR, SOD1, PTK2, NTRK2 |
regulation of hair cycle | biological_process | CLOCK |
regulation of hair cycle by canonical Wnt signaling pathway | biological_process | CDH3 |
regulation of hair follicle development | biological_process | HPSE, SMAD4 |
regulation of heart contraction | biological_process | GJA1 |
regulation of heart induction by regulation of canonical Wnt signaling pathway | biological_process | POU5F1 |
regulation of heart rate | biological_process | GJA1, DRD2, SEMA3A |
regulation of hematopoietic stem cell proliferation | biological_process | ACE |
regulation of hepatocyte proliferation | biological_process | IFNG, PLAU |
regulation of histone acetylation | biological_process | GATA2 |
regulation of histone H3-K27 methylation | biological_process | GATA3 |
regulation of histone H3-K4 methylation | biological_process | GATA3 |
regulation of histone methylation | biological_process | MTHFR |
regulation of homophilic cell adhesion | biological_process | PTPRR |
regulation of hormone secretion | biological_process | ANXA1 |
regulation of humoral immune response | biological_process | CXCL13 |
regulation of hydrogen peroxide metabolic process | biological_process | INSR, RAC1 |
regulation of I-kappaB kinase/NF-kappaB signaling | biological_process | TNF, HSPB1, IL1B, F2RL1, ANGPT1 |
regulation of immune response | biological_process | BCL6, CD40LG, CD40, HLA-C, HLA-E, KLRC1, VCAM1, HLA-G, KIR2DL1, KIR2DL3, FCER1G, HLA-A, KIR3DL1, ITGB1, IFNG, C3, NCR1, ITGB2, HLA-B, ICAM1, IL4, SMAD3, KLRD1, MICA, MICB, TBX21, CD1A, KLRK1, LILRB1 |
regulation of immunoglobulin production | biological_process | FOXP3 |
regulation of immunoglobulin secretion | biological_process | CD40LG, CD40, TNF |
regulation of inflammatory response | biological_process | BCL6, CASP1, AGTR1, IL1R1, SELE, CMA1, PTGS2, ANXA1, AHSG, TLR4, IL4, RELA, PARK7, FOXP1, NOD2 |
regulation of innate immune response | biological_process | PTPN22 |
regulation of insulin secretion | biological_process | NOS2, CCL5, LEP, SSTR5, IFNG, CLOCK, TNF, IL1B |
regulation of insulin-like growth factor receptor signaling pathway | biological_process | IGFBP2, IGFBP3, IGFBP1, IGFBP4 |
regulation of integrin activation | biological_process | SELP |
regulation of integrin-mediated signaling pathway | biological_process | TIMP1 |
regulation of interferon-gamma production | biological_process | CCR7 |
regulation of interferon-gamma-mediated signaling pathway | biological_process | JAK1, IFNG, SOCS3 |
regulation of interleukin-1 beta production | biological_process | F2R |
regulation of interleukin-1 beta secretion | biological_process | FOXP1, CCR7 |
regulation of interleukin-1 production | biological_process | ANXA1 |
regulation of interleukin-10 secretion | biological_process | HLA-DRB1 |
regulation of interleukin-12 production | biological_process | HLA-B |
regulation of interleukin-12 secretion | biological_process | FOXP1 |
regulation of interleukin-2 biosynthetic process | biological_process | IL17F |
regulation of interleukin-23 production | biological_process | TGFB1 |
regulation of interleukin-4 production | biological_process | HLA-DRB1, LGALS9 |
regulation of interleukin-5 production | biological_process | LGALS9 |
regulation of interleukin-6 biosynthetic process | biological_process | IL17F |
regulation of interleukin-6 production | biological_process | HLA-B |
regulation of interleukin-8 biosynthetic process | biological_process | IL17F |
regulation of interleukin-8 secretion | biological_process | CRP |
regulation of intestinal cholesterol absorption | biological_process | LEP, APOA1, APOA2 |
regulation of intracellular estrogen receptor signaling pathway | biological_process | SRC |
regulation of intracellular pH | biological_process | ATP5B, CA2, SLC26A8 |
regulation of ion transmembrane transport | biological_process | CLCN3 |
regulation of IRE1-mediated unfolded protein response | biological_process | COPS5 |
regulation of isotype switching | biological_process | IL10, IL4 |
regulation of isotype switching to IgG isotypes | biological_process | FOXP3 |
regulation of JNK cascade | biological_process | IGF1R, COPS5, F2RL1 |
regulation of keratinocyte differentiation | biological_process | ERRFI1 |
regulation of keratinocyte proliferation | biological_process | YAP1 |
regulation of lateral mesodermal cell fate specification | biological_process | FGFR1 |
regulation of leukocyte mediated cytotoxicity | biological_process | ICAM1 |
regulation of leukocyte migration | biological_process | CXCR3, ANXA1 |
regulation of lipid catabolic process | biological_process | RARRES2 |
regulation of lipid kinase activity | biological_process | RB1 |
regulation of lipid metabolic process | biological_process | PPARG, PSAP, ID2, IRS2, ADIPOR1 |
regulation of lipid storage | biological_process | SIRT1 |
regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter | biological_process | PPARA |
regulation of lipoprotein lipid oxidation | biological_process | LEP |
regulation of locomotion involved in locomotory behavior | biological_process | DRD2 |
regulation of long-term neuronal synaptic plasticity | biological_process | DRD2, KRAS, SYP |
regulation of lymphocyte differentiation | biological_process | FAS |
regulation of macroautophagy | biological_process | CASP3, UCHL1 |
regulation of macrophage activation | biological_process | MIF, CD74 |
regulation of macrophage colony-stimulating factor production | biological_process | FOXP1 |
regulation of macrophage derived foam cell differentiation | biological_process | CSF1 |
regulation of macrophage migration inhibitory factor signaling pathway | biological_process | ANGPT1 |
regulation of mammary gland epithelial cell proliferation | biological_process | GPX1, BAX |
regulation of MAPK cascade | biological_process | INHBA, DRD2, ID1, BMP6, INHA, MSTN, GDF9, PSAP, GDF15, HRH4 |
regulation of mast cell apoptotic process | biological_process | ADAM17 |
regulation of membrane permeability | biological_process | MTOR |
regulation of membrane potential | biological_process | SLC26A8 |
regulation of memory T cell differentiation | biological_process | BCL6 |
regulation of mesenchymal cell proliferation | biological_process | ZEB1 |
regulation of mesenchymal stem cell differentiation | biological_process | PDGFRA |
regulation of metabolic process | biological_process | LEP, NTRK2 |
regulation of metanephric nephron tubule epithelial cell differentiation | biological_process | YAP1, LIF, PAX2 |
regulation of metanephros size | biological_process | AGTR2, PAX2 |
regulation of methylation-dependent chromatin silencing | biological_process | POU5F1 |
regulation of microtubule polymerization or depolymerization | biological_process | STMN1 |
regulation of microtubule-based process | biological_process | GSK3B, ERBB2 |
regulation of mitochondrial depolarization | biological_process | GCLC |
regulation of mitochondrial membrane permeability | biological_process | BCL2, STAT3, TP53, BCL2L1 |
regulation of mitochondrial membrane permeability involved in apoptotic process | biological_process | BAX |
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death | biological_process | BAX |
regulation of mitochondrial membrane potential | biological_process | BCL2, NDUFS1, SOD1, BCL2L1, PARK7, BAX |
regulation of mitotic cell cycle | biological_process | CDKN1A, RB1, PLK1, SIRT1, PIM2, RPRM |
regulation of mitotic cell cycle spindle assembly checkpoint | biological_process | CCNB1 |
regulation of mitotic centrosome separation | biological_process | CEP85 |
regulation of mitotic metaphase/anaphase transition | biological_process | PLK1 |
regulation of mitotic nuclear division | biological_process | CDC42 |
regulation of mitotic spindle assembly | biological_process | PLK1 |
regulation of monocyte differentiation | biological_process | FOXP1 |
regulation of morphogenesis of a branching structure | biological_process | BMP4, FGFR2 |
regulation of mRNA splicing, via spliceosome | biological_process | TIA1 |
regulation of mRNA stability | biological_process | APEX1, AKT1, PSMD9, HSPB1, PSMD10, SET, ELAVL1 |
regulation of multicellular organism growth | biological_process | STAT3, FGFR2, PIK3CA, IGF1, SOD1, PRL |
regulation of myelination | biological_process | AKT1, CTNNB1, MTOR, HES5 |
regulation of myeloid cell apoptotic process | biological_process | PTEN |
regulation of myeloid cell differentiation | biological_process | FAS |
regulation of N-methyl-D-aspartate selective glutamate receptor activity | biological_process | OPRM1, CRHBP, CRH, DAPK1 |
regulation of natural killer cell activation | biological_process | LEP |
regulation of natural killer cell mediated cytotoxicity | biological_process | LEP, NCR1 |
regulation of natural killer cell mediated immunity | biological_process | HLA-E |
regulation of natural killer cell proliferation | biological_process | LEP, PTPN22 |
regulation of necrotic cell death | biological_process | OLFM4 |
regulation of nephron tubule epithelial cell differentiation | biological_process | GATA3, CTNNB1 |
regulation of neural precursor cell proliferation | biological_process | FOXO1 |
regulation of neural retina development | biological_process | DLL4 |
regulation of neurogenesis | biological_process | YAP1, BCL6, CTNNB1, NOTCH1, HES5, EZH2, DLL4 |
regulation of neuron apoptotic process | biological_process | GATA3, ESR1, GPX1, PARK7, BAX, ESR2, TP63 |
regulation of neuron death | biological_process | CCL5, CLU, APOE |
regulation of neuron differentiation | biological_process | NTF4, NGF, DPYSL2, YWHAH |
regulation of neuron maturation | biological_process | RAC1 |
regulation of neuron projection development | biological_process | GSK3B, GATA3, AKT1, PTEN, DPYSL2 |
regulation of neuronal action potential | biological_process | IFNG |
regulation of neuronal signal transduction | biological_process | CLU |
regulation of neuronal synaptic plasticity | biological_process | GSK3B, STAR, APOE, SYP |
regulation of neurotransmitter secretion | biological_process | SNCG, NTRK2 |
regulation of neutrophil extravasation | biological_process | OLFM4 |
regulation of NIK/NF-kappaB signaling | biological_process | RASSF2, PTPN22 |
regulation of nitric-oxide synthase activity | biological_process | LEP, AKT1, NOS3, HSP90AA1, EGFR, IL1B |
regulation of nitrogen utilization | biological_process | BCL2, BAX |
regulation of norepinephrine secretion | biological_process | PTGER3 |
regulation of Notch signaling pathway | biological_process | NOTCH1, IL6ST, POSTN |
regulation of nucleic acid-templated transcription | biological_process | ACTN4, SRA1 |
regulation of nucleotide-excision repair | biological_process | HMGB1 |
regulation of odontogenesis of dentin-containing tooth | biological_process | BMP4 |
regulation of oligodendrocyte differentiation | biological_process | TNFRSF21 |
regulation of opioid receptor signaling pathway | biological_process | SYP |
regulation of opsonization | biological_process | C4BPA |
regulation of organ growth | biological_process | SOD1, LATS1, BCL2L11 |
regulation of ossification | biological_process | PTGER4, CSF1 |
regulation of osteoblast differentiation | biological_process | FGFR2, CTNNB1, RASSF2, PTK2 |
regulation of osteoblast proliferation | biological_process | FGFR2, RHOA |
regulation of osteoclast differentiation | biological_process | FSHR, CTNNB1, RASSF2, MTOR, TNF, FSHB |
regulation of oxidative phosphorylation | biological_process | ATP7A |
regulation of p38MAPK cascade | biological_process | HGF, LGALS9 |
regulation of pathway-restricted SMAD protein phosphorylation | biological_process | BMP4 |
regulation of peptidyl-tyrosine phosphorylation | biological_process | EFNA1, EGFR, PDGFA, ITGB2, EGF |
regulation of peroxisome proliferator activated receptor signaling pathway | biological_process | ALOX15, SIRT1 |
regulation of pH | biological_process | CLCN3, EDN1 |
regulation of phagocytosis | biological_process | ITGAV, SCARB1, OLFM4 |
regulation of phosphatidylcholine catabolic process | biological_process | SCARB1 |
regulation of phosphatidylinositol 3-kinase activity | biological_process | PIK3R1 |
regulation of phosphatidylinositol 3-kinase signaling | biological_process | FGFR1, FGF2, MAPK1, FGFR2, PIK3R1, KIT, AKT1, ERBB3, PDGFRA, KITLG, PIK3CA, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, NRG1, IRS2 |
regulation of phosphoprotein phosphatase activity | biological_process | DRD2 |
regulation of phosphorylation | biological_process | ENG, IL4 |
regulation of plasma lipoprotein particle levels | biological_process | LIPC |
regulation of platelet activation | biological_process | FCER1G |
regulation of podosome assembly | biological_process | SRC |
regulation of potassium ion transmembrane transport | biological_process | DPP6 |
regulation of potassium ion transport | biological_process | DRD2 |
regulation of primitive erythrocyte differentiation | biological_process | GATA2 |
regulation of progesterone secretion | biological_process | GDF9 |
regulation of programmed cell death | biological_process | BCL2, CXCR4 |
regulation of pronephros size | biological_process | HNF1B |
regulation of proteasomal protein catabolic process | biological_process | GPX1 |
regulation of protein ADP-ribosylation | biological_process | KAT2B |
regulation of protein binding | biological_process | SRC, PLK1, ANGPT1 |
regulation of protein catabolic process | biological_process | CHEK2, CDC42 |
regulation of protein complex assembly | biological_process | HSP90AA1, LATS1 |
regulation of protein export from nucleus | biological_process | CDKN2A |
regulation of protein heterodimerization activity | biological_process | BCL2, CDC42, NRG1, BAX |
regulation of protein homodimerization activity | biological_process | BCL2, NRG1, BAX |
regulation of protein import into nucleus | biological_process | BMP4, TGFB1 |
regulation of protein import into nucleus, translocation | biological_process | TXN, CDKN1A, SIRT1, OGG1 |
regulation of protein kinase A signaling | biological_process | FSHR |
regulation of protein kinase activity | biological_process | HMGB1, MTOR, SOD1, CXCL10, CDC42 |
regulation of protein kinase B signaling | biological_process | MTOR, NTRK2 |
regulation of protein localization | biological_process | BCL2, WNT5A, AKT1 |
regulation of protein localization to cell surface | biological_process | CTNNB1, EGF |
regulation of protein localization to nucleus | biological_process | LEP |
regulation of protein metabolic process | biological_process | HPX, CDC42 |
regulation of protein phosphatase type 2A activity | biological_process | SET |
regulation of protein phosphorylation | biological_process | LEP, FN1, APOA1, TNF, SOCS3, PTK2, EZH2 |
regulation of protein secretion | biological_process | SAA1, TNF |
regulation of protein serine/threonine kinase activity | biological_process | SIRT1 |
regulation of protein stability | biological_process | BCL2, MAPK1, AURKA, APOA2, TERT, KRAS, TF, CDC42, PTEN, CDKN2A |
regulation of protein sumoylation | biological_process | EGR1 |
regulation of protein targeting to mitochondrion | biological_process | CDKN2A |
regulation of protein ubiquitination | biological_process | HSP90AA1 |
regulation of proteolysis | biological_process | PLAUR |
regulation of proton transport | biological_process | IL13, IL4 |
regulation of Rac protein signal transduction | biological_process | CRK |
regulation of Rap protein signal transduction | biological_process | TIMP2 |
regulation of reactive oxygen species metabolic process | biological_process | TNF, FOXO1, CYP1B1 |
regulation of receptor activity | biological_process | SERPINE1, PLAU |
regulation of receptor internalization | biological_process | DKK1 |
regulation of regulatory T cell differentiation | biological_process | TGFB1 |
regulation of removal of superoxide radicals | biological_process | CD36, NFE2L2 |
regulation of renal output by angiotensin | biological_process | ACE |
regulation of renal sodium excretion | biological_process | AGTR1 |
regulation of respiratory burst | biological_process | RAC1 |
regulation of response to DNA damage stimulus | biological_process | MCL1 |
regulation of response to food | biological_process | MTOR, GHRL |
regulation of restriction endodeoxyribonuclease activity | biological_process | HMGB1 |
regulation of retinal cell programmed cell death | biological_process | CNTF |
regulation of retinal ganglion cell axon guidance | biological_process | VEGFA, NRP1 |
regulation of retinoic acid receptor signaling pathway | biological_process | AKR1C3 |
regulation of Rho protein signal transduction | biological_process | KALRN |
regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological_process | LIF |
regulation of ruffle assembly | biological_process | ICAM1 |
regulation of secondary heart field cardioblast proliferation | biological_process | CTNNB1 |
regulation of sensory perception of pain | biological_process | FGFR1, F2R, IL10, OPRM1, CCL3, COMT, EDN1 |
regulation of sequence-specific DNA binding transcription factor activity | biological_process | MAPK1, ATF2, HMOX1, JUN, SGK1, FOS |
regulation of serotonin secretion | biological_process | CRH |
regulation of short-term neuronal synaptic plasticity | biological_process | SYP |
regulation of signal transduction | biological_process | TDGF1, BIRC5, SPRY2, NODAL |
regulation of signal transduction by p53 class mediator | biological_process | AKT1, BRCA1, CHEK2, AURKA, TP53, HDAC2, HDAC1, ATM, EHMT2, TP63 |
regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological_process | CXCL8 |
regulation of skeletal muscle satellite cell proliferation | biological_process | ANGPT1 |
regulation of SMAD protein import into nucleus | biological_process | TGFB1 |
regulation of small GTPase mediated signal transduction | biological_process | RHOC, A2M, KALRN, CDC42, RAC1, RHOA |
regulation of smooth muscle cell apoptotic process | biological_process | SIRT1 |
regulation of smooth muscle cell differentiation | biological_process | BMP4, FGFR2, ZEB1 |
regulation of smooth muscle cell migration | biological_process | ACE, TACR1, PDGFA, PLAU |
regulation of smooth muscle cell proliferation | biological_process | BMP4, CTNNB1, TACR1 |
regulation of smooth muscle cell-matrix adhesion | biological_process | PLAU |
regulation of smooth muscle contraction | biological_process | FLT1 |
regulation of smoothened signaling pathway | biological_process | FGFR2 |
regulation of sodium ion transmembrane transporter activity | biological_process | YWHAH |
regulation of sodium ion transport | biological_process | DRD2, NOS3, TGFB1, YWHAH |
regulation of somitogenesis | biological_process | CDX1, NOTCH1 |
regulation of stem cell population maintenance | biological_process | HMGA2, ELAVL1, NODAL |
regulation of stem cell proliferation | biological_process | FGFR1, YAP1 |
regulation of steroid biosynthetic process | biological_process | LEP, STAR, NR5A1 |
regulation of store-operated calcium entry | biological_process | SPINK1 |
regulation of stress fiber assembly | biological_process | PIK3R1, PTGER4 |
regulation of stress-activated MAPK cascade | biological_process | MAPK1, GSTP1, GREM1 |
regulation of striated muscle tissue development | biological_process | TGFB1, SMAD3 |
regulation of substrate adhesion-dependent cell spreading | biological_process | PTK2 |
regulation of supramolecular fiber organization | biological_process | PARK7 |
regulation of synapse assembly | biological_process | NECTIN1 |
regulation of synapse organization | biological_process | DKK1 |
regulation of synapse structural plasticity | biological_process | DRD2 |
regulation of synaptic plasticity | biological_process | NCAM1, YWHAH, P2RX3 |
regulation of synaptic transmission, GABAergic | biological_process | DRD2, KRAS, PTEN |
regulation of synaptic transmission, glutamatergic | biological_process | DKK1, UCN |
regulation of synaptic vesicle clustering | biological_process | PCDH17 |
regulation of systemic arterial blood pressure | biological_process | PLCB3, POSTN |
regulation of systemic arterial blood pressure by circulatory renin-angiotensin | biological_process | AGTR2 |
regulation of systemic arterial blood pressure by endothelin | biological_process | NOS3, EDN1 |
regulation of systemic arterial blood pressure by renin-angiotensin | biological_process | ACE, AGTR1 |
regulation of systemic arterial blood pressure by vasopressin | biological_process | OXTR |
regulation of T cell activation | biological_process | CCL5, CD4, IL20RB |
regulation of T cell anergy | biological_process | HLA-B, FOXP3 |
regulation of T cell apoptotic process | biological_process | LGALS3 |
regulation of T cell chemotaxis | biological_process | CXCL10 |
regulation of T cell differentiation | biological_process | IL15, ADA |
regulation of T cell differentiation in thymus | biological_process | ZEB1, SOD1 |
regulation of T cell homeostatic proliferation | biological_process | IL2RA, IL2 |
regulation of T cell mediated cytotoxicity | biological_process | AGER |
regulation of T cell mediated immune response to tumor cell | biological_process | HMGB1 |
regulation of T cell proliferation | biological_process | LGALS3, CTNNB1, IL27 |
regulation of T cell receptor signaling pathway | biological_process | PTPN22 |
regulation of T cell tolerance induction | biological_process | IL2RA |
regulation of T-helper 1 cell differentiation | biological_process | IL27 |
regulation of tau-protein kinase activity | biological_process | HGF, APOE |
regulation of telomerase activity | biological_process | ATM |
regulation of telomere maintenance | biological_process | MYC |
regulation of testosterone biosynthetic process | biological_process | AKR1C3 |
regulation of the force of heart contraction | biological_process | ADM, IFNG |
regulation of the force of heart contraction by chemical signal | biological_process | NOS3 |
regulation of thymocyte apoptotic process | biological_process | HIF1A |
regulation of tolerance induction | biological_process | HMGB1 |
regulation of TRAIL receptor biosynthetic process | biological_process | PARK7 |
regulation of transcription factor import into nucleus | biological_process | AGTR2 |
regulation of transcription from RNA polymerase II promoter | biological_process | CRK, GATA3, INHBA, VEGFA, BCL6, STAT3, NR2F2, PPARG, HMGB1, CTNNB1, ATF2, BRCA1, NFKB1, AHR, NOTCH1, ANXA4, USF1, STAT6, WT1, ZEB1, CLOCK, PRKCB, FSTL3, RB1, ARID1A, SOX15, SNAI1, FOS, RUNX3, SMAD3, FOXP1, FOXO1, NR5A1, NFKB2, FOXP3, EZH2, SMAD4, USF2, KLF9, MAF |
regulation of transcription from RNA polymerase II promoter by glucose | biological_process | USF1, USF2 |
regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological_process | EGR1, VEGFA, ARNT, HIF1A |
regulation of transcription from RNA polymerase II promoter in response to iron | biological_process | HMOX1 |
regulation of transcription from RNA polymerase II promoter in response to oxidative stress | biological_process | HMOX1, ARNT, HIF1A |
regulation of transcription from RNA polymerase II promoter in response to stress | biological_process | MUC1 |
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | biological_process | NOTCH1 |
regulation of transcription from RNA polymerase III promoter | biological_process | BRCA1 |
regulation of transcription involved in cell fate commitment | biological_process | PPARG, CHD5 |
regulation of transcription involved in G1/S transition of mitotic cell cycle | biological_process | PCNA, RB1, KLF11 |
regulation of transcription involved in lymphatic endothelial cell fate commitment | biological_process | NR2F2 |
regulation of transcription, DNA-templated | biological_process | FGFR1, EGR1, TXN, GATA3, YAP1, CCND1, BCL6, STAT3, NR2F2, DNMT1, CDX1, HMGA2, PPARG, MAPK1, APEX1, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, AHR, NOTCH1, ID1, FASLG, VDR, ENG, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ZEB1, CHEK2, ESR1, INSR, JUN, IFNG, CLOCK, MAP3K7, PRKCB, FSTL3, LTF, TP53, SUV39H1, MYC, BIRC5, ENO1, ERBB2, SMAD7, MEIS1, NR5A2, RB1, ARID1A, SOX15, KLF11, FOS, NR3C1, KHDRBS3, PRDM1, PGR, IGF2, C1QBP, RUNX3, YBX1, HDAC2, SMAD3, RELA, FOXL2, HIF1A, FOXP1, HES5, ATP1B4, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, NFKB2, POU5F1, KAT2B, HDAC1, FOXP3, EZH2, SIRT1, ID2, STAT4, SMAD4, TWIST1, NR0B2, ZNF366, CDKN2A, TP63, EMX2, KLF10, GATA6, NAA15, SUV39H2, PAX2, USF2, DLX5, KLF9, IL16, PPRC1, TBPL2, NOTCH4, CHD5, NANOG, GATA5, TBX21, AHRR, OGG1, MAF, FHIT, TET1, CREB3L1, SRA1, MBD2, PIAS3 |
regulation of transforming growth factor beta receptor signaling pathway | biological_process | ITGA3, FOLR1, ENG, ZEB1, TGFB1, SMAD7, SMAD3, SMAD2, SMAD4, IL17F |
regulation of transforming growth factor beta2 production | biological_process | TGFB2, SMAD3, HIF1A, SMAD4 |
regulation of translation | biological_process | AKT1, IGF1, EIF4EBP1, DAPK1 |
regulation of translational initiation | biological_process | HSPB1, EIF3E |
regulation of transmembrane transporter activity | biological_process | BCL2 |
regulation of triglyceride biosynthetic process | biological_process | C3 |
regulation of tumor necrosis factor production | biological_process | LTF, FOXP1, ANGPT1 |
regulation of tumor necrosis factor-mediated signaling pathway | biological_process | TNFRSF1A, TNF |
regulation of type B pancreatic cell development | biological_process | CLOCK |
regulation of type B pancreatic cell proliferation | biological_process | ERRFI1 |
regulation of type I interferon-mediated signaling pathway | biological_process | JAK1, TYK2 |
regulation of tyrosine phosphorylation of Stat1 protein | biological_process | IL12B, IL23A |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | biological_process | CCNB1, PLK1 |
regulation of uterine smooth muscle contraction | biological_process | TACR2, TACR1 |
regulation of vascular endothelial growth factor production | biological_process | CCL2, CCR2, IL6 |
regulation of vascular endothelial growth factor receptor signaling pathway | biological_process | VEGFC, FIGF |
regulation of vascular endothelial growth factor signaling pathway | biological_process | PTP4A3 |
regulation of vascular permeability | biological_process | SRC, TEK |
regulation of vasculature development | biological_process | ID1 |
regulation of vasculogenesis | biological_process | HEY1 |
regulation of vasoconstriction | biological_process | ACE, AGTR1, EDN1 |
regulation of vasodilation | biological_process | ACE, AGTR1, AGTR2 |
regulation of ventricular cardiac muscle cell membrane depolarization | biological_process | GJA1, SMAD7 |
regulation of ventricular cardiac muscle cell membrane repolarization | biological_process | GJA1 |
regulation of vesicle-mediated transport | biological_process | NRP1 |
regulation of viral genome replication | biological_process | BCL2 |
regulation of Wnt signaling pathway | biological_process | ITGA3, HNF1B, DKK1 |
regulation of wound healing | biological_process | PLAU |
regulatory T cell differentiation | biological_process | TGFB1, FOXP3 |
relaxation of vascular smooth muscle | biological_process | SOD1 |
release of cytochrome c from mitochondria | biological_process | BCL2, CLU, JUN, BCL2L1, BAX |
release of matrix enzymes from mitochondria | biological_process | BAX |
release of sequestered calcium ion into cytosol | biological_process | FGF2, F2R, DRD2, CCL21, CCL19, TRPV1, CCR7 |
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | biological_process | CCL3, CCR5 |
removal of superoxide radicals | biological_process | NOS3, SOD1, MPO, ATP7A |
renal absorption | biological_process | AKR1C3 |
renal artery morphogenesis | biological_process | NRP1 |
renal filtration | biological_process | ITGA3 |
renal inner medulla development | biological_process | CTNNB1 |
renal outer medulla development | biological_process | CTNNB1 |
renal sodium ion absorption | biological_process | SGK1 |
renal system development | biological_process | GATA3, ITGA6, BMP4, CTNNB1, EMX2 |
renal system process | biological_process | BCL2, BMP4, FAS |
renal tubule morphogenesis | biological_process | COL4A1 |
renal vesicle formation | biological_process | CTNNB1, WNT4 |
renal vesicle induction | biological_process | WNT4 |
renal water homeostasis | biological_process | AQP2 |
renal water transport | biological_process | AQP2 |
renin secretion into blood stream | biological_process | PCSK5 |
renin-angiotensin regulation of aldosterone production | biological_process | AGTR1, AGTR2 |
replication fork processing | biological_process | PCNA |
replication fork protection | biological_process | BRCA2 |
replicative cell aging | biological_process | CHEK2, TP63 |
replicative senescence | biological_process | MME, CDKN1A, CDKN2A, CHEK2, TP53, TERT, ATM |
reproductive process | biological_process | NR5A1 |
reproductive structure development | biological_process | FGFR2, FKBP4 |
resolution of meiotic recombination intermediates | biological_process | MLH1 |
resolution of mitotic recombination intermediates | biological_process | XRCC3 |
respiratory burst involved in defense response | biological_process | MPO |
respiratory gaseous exchange | biological_process | CFTR, CSF2RB, EDNRA, EDN1, SFTPA1 |
respiratory system development | biological_process | SPRY2 |
respiratory tube development | biological_process | PCSK5 |
response to acetate | biological_process | LIPC, CYP17A1 |
response to acidic pH | biological_process | SRC, SERPINF1, SST |
response to activity | biological_process | GSK3B, DNMT1, CCL5, IL10, LEP, CTNNB1, CCL2, PTN, BMP6, STAR, INSR, IGF1, ITGB1, ANGPT2, PLAU, CAT, EDN1, HIF1A, ADIPOQ, ESR2, AGER, DNMT3B |
response to alkaloid | biological_process | BCHE, HIF1A |
response to amine | biological_process | NME1, ITGA2, CTSB |
response to amino acid | biological_process | MTHFR, PTGER4, CDKN1B, CASP3, GSTP1, LIPC, CCL2, MTOR, TIMP3, ICAM1, IL6, EDN1, RELA, SST, IL17A, PEMT |
response to amphetamine | biological_process | DRD2, OXTR, SOD1, ICAM1, HDAC2, DPYSL2 |
response to anesthetic | biological_process | HIF1A |
response to angiotensin | biological_process | GSK3B |
response to anoxia | biological_process | OXTR |
response to antibiotic | biological_process | ID1, CASP3, JAK1, CCL2, STAR, HSP90AA1, SOD1, TP53, CYP1A1, IL6 |
response to antidepressant | biological_process | DNMT1, DNMT3A |
response to antipsychotic drug | biological_process | SOD1 |
response to arsenic-containing substance | biological_process | GCLC, SERPINF1, CDKN1A, TNFRSF11B, CYP1A1, PTEN |
response to ATP | biological_process | CASP1, IL1B, PTEN, P2RX3 |
response to auditory stimulus | biological_process | TACR1, CXCL10, IL6, NTRK2, HIF1A, UCN |
response to axon injury | biological_process | FOLR1, DRD2, LGALS1, SOD1, BAX, AIF1 |
response to bacterium | biological_process | NOS2, CCL5, NFKB1, CASP1, CCL2, TLR4, SOCS3, IL6, RELA, DEFB1, IL27 |
response to bisphenol A | biological_process | ESR2 |
response to cadmium ion | biological_process | PCNA, CTNNB1, CDKN1B, SPARC, CAT |
response to caffeine | biological_process | DNMT1, PPARG, IGF1, IL6, HDAC2, DNMT3B |
response to calcium ion | biological_process | CCND1, PLA2G4A, ANXA5, SPARC, LIPC, SDC1, FGA, PTGES, PDCD6, THBS1, IL6 |
response to cAMP | biological_process | NME1, BRAF, SPARC, SDC1, BSG, CYP17A1, JUN, FOS, RELA, TEK |
response to carbohydrate | biological_process | LIPC, HNF1B, IL1B, P2RX3 |
response to carbon monoxide | biological_process | IL10, SOD1 |
response to cholesterol | biological_process | CCL5, CCL3, CCR5, TGFB1, SMAD2 |
response to ciliary neurotrophic factor | biological_process | PTN |
response to cobalamin | biological_process | RELA |
response to cobalt ion | biological_process | CASP3, HIF1A |
response to cocaine | biological_process | OPRM1, DRD2, MTOR, OXTR, CRH, HDAC2, DNMT3A, DPYSL2, BAX, DNMT3B |
response to cold | biological_process | HSPD1, PPARG, ADM, HSP90AA1, MT-CO2, CXCL10, FOS, IL6, P2RX3 |
response to copper ion | biological_process | NFKB1, LIPC, SOD1, IL1A, CP, ICAM1, BAX, S100A13, ATP7A |
response to corticosteroid | biological_process | NOTCH1, ANXA1 |
response to corticosterone | biological_process | CCND1, CDKN1A, PTGS1, STAR, FOS, CRH, BAX |
response to cycloheximide | biological_process | FAS, FGA, BCL2L1 |
response to cytokine | biological_process | BCL2, STAT3, CCL5, CTNNB1, IL6R, IL6ST, SPARC, FAS, LIFR, TIMP2, STAT6, OXTR, PTGS2, CYP17A1, JUN, TIMP1, PTGES, SOCS3, FOS, CTSB, IL4, IL6, RELA, BCL2L1, AIF1, MCL1, NFKB2, TIMP4, CXCL16 |
response to DDT | biological_process | CCNB1 |
response to dexamethasone | biological_process | IL1B, EDN1, ESR2 |
response to dietary excess | biological_process | LEP, APOE |
response to diuretic | biological_process | PPARG, IL1B |
response to doxorubicin | biological_process | CHEK2 |
response to drug | biological_process | GSK3B, BCL2, SRC, CDH1, GATA3, INHBA, CCND1, STAT3, DNMT1, ITGA3, PPARG, MMP13, CCL5, IGFBP2, APEX1, IL10, CTNNB1, CCNB1, MTHFR, PTGER4, SLC6A4, CDKN1B, NME1, DRD2, CASP3, CDKN1A, XRCC1, ITGA2, LGALS1, LIPC, FAS, CCL2, TIMP2, HNF1B, PTN, MDK, COMT, CDH3, OXTR, SRD5A2, PTGS2, VEGFC, COL18A1, MMP12, PTGER3, STAR, ITGB1, CYP17A1, JUN, IFNG, TGFB1, ANXA1, CYP2E1, SOD1, APOA1, BCHE, APOA2, MYC, PDGFA, CYP1A2, FYN, TNFRSF11B, SOCS3, FOS, THBS1, IL1B, PNP, ADA, IGF2, LTA, ICAM1, AMH, CAT, CYP1A1, IL4, IL6, EDN1, CRH, ABCB1, PTEN, TGFB2, HDAC2, RELA, DNMT3A, PARK7, HIF1A, DPYSL2, BAX, ADIPOQ, ESR2, ADAM17, DNMT3B, BLMH, EMX2, GATA6, ABCG2, PMS2, SST, DAD1, HSD11B2, CPB2, TIMP4, SEMA3C, OGG1, SRD5A1, PEMT |
response to dsRNA | biological_process | TLR3 |
response to electrical stimulus | biological_process | SRC, TACR2, TACR1, MSTN, IL6, S100A13, AIF1 |
response to endoplasmic reticulum stress | biological_process | PIK3R1, ALOX15, CXCL8, BCL2L11, THBS1, AGR2, NFE2L2 |
response to epidermal growth factor | biological_process | MAPK1, IL1R1 |
response to epinephrine | biological_process | GSK3B |
response to estradiol | biological_process | GSK3B, CCND1, STAT3, NR2F2, BMP4, DNMT1, WNT5A, IGFBP2, F3, LEP, CTNNB1, BRCA1, SLC6A4, AHR, CDKN1B, CASP3, BRCA2, GSTP1, TACR1, PTN, OXTR, PTGS2, PTGFR, PTGER3, AURKA, ESR1, INSR, CRYAB, TGFB1, ANXA1, FGA, PDGFA, C3, CD4, CYP1A2, WNT7A, SOCS3, IL1B, IGF2, GC, CAT, PTEN, DNMT3A, HIF1A, ESR2, EZH2, DNMT3B, UCN, IHH, POSTN, OGG1, SRD5A1 |
response to estrogen | biological_process | GATA3, CCND1, PPARG, MMP13, CCL5, MAPK1, IGFBP2, CTNNB1, BRCA1, KRT19, CTNNA1, STS, HMOX1, FAS, MMP14, TIMP3, STAR, ESR1, CA2, HSP90AA1, APOA1, APOA2, C3, TNFRSF11B, WNT7A, MSTN, CRH, HIF1A, TEK, GHRL, ESR2, ZNF366, GATA6, SRD5A1 |
response to ethanol | biological_process | GATA3, CCND1, STAT3, DNMT1, LEP, OPRM1, DRD2, SPARC, GSTP1, CCL2, VCAM1, TACR1, TNC, IL13, STAR, INSR, CYP2E1, SOD1, FYN, MSTN, CTSB, IL1B, IGF2, ICAM1, CAT, IL4, CRH, PTEN, DNMT3A, EIF4EBP1, ADIPOQ, ESR2, IL2, OGG1, PEMT |
response to ether | biological_process | CRH |
response to exogenous dsRNA | biological_process | MAPK1, TLR3 |
response to external stimulus | biological_process | PON1, INHA |
response to fatty acid | biological_process | SRC, CD36, LIPC, PTGS1, PON1, PTGS2, CAT |
response to fibroblast growth factor | biological_process | TNC |
response to fluid shear stress | biological_process | GJA1, F3, AKT1, NOS3 |
response to fluoride | biological_process | FAS, PON1, FOXO1 |
response to folic acid | biological_process | MTHFR, TIMP3, BCHE, ABCG2, OGG1 |
response to follicle-stimulating hormone | biological_process | SRD5A2, SRD5A1 |
response to food | biological_process | OPRM1, AKT1, SOCS3, GHRH, CYP1A1, MPO, HSD11B2 |
response to fructose | biological_process | PTGS2, AGER |
response to fungicide | biological_process | STAR, CYP17A1, HIF1A, SRD5A1 |
response to gamma radiation | biological_process | BCL2, GATA3, BRCA2, CCL2, CHEK2, TP53, MYC, CXCL10, SOCS3, IL1B, GPX1, BAX, TP63, CCL7 |
response to genistein | biological_process | FGA, ESR2, AGER |
response to glucocorticoid | biological_process | BCL2, CCND1, BMP4, PLA2G4A, WNT5A, PTGDS, CCL5, HMGB1, IGFBP2, IL10, SHC1, CASP3, CDKN1A, SPARC, LIPC, FAS, CCL2, IL1RN, SDC1, MDK, BMP6, ADM, PTGS2, FN1, INSR, IGF1, ANXA1, BCHE, APOA2, TNF, C3, SOCS3, MSTN, IL1B, KRAS, IL6, HIF1A, ADIPOQ, AIF1, UCN, HSD11B2, IL22 |
response to glucose | biological_process | EGR1, GJA1, CDKN1B, CASP3, HNF1B, TGFB1, APOA2, ANGPT2, THBS1, CTSB, PTEN, HIF1A, SMAD2, ADIPOQ, NR0B2, IRS2 |
response to gold nanoparticle | biological_process | MPO |
response to gonadotropin | biological_process | ITGA3, STAR, ITGB1, CYP17A1, ICAM1 |
response to gravity | biological_process | SPARC, MSTN, FOS |
response to growth factor | biological_process | OPRM1, FASLG, FAS, SOX2, MYC, GATA6 |
response to growth hormone | biological_process | AKT1, IGFBP5, SRD5A1 |
response to heat | biological_process | GCLC, DNMT1, PLA2G4A, AKT1, CCL2, TACR1, NOS3, CXCL12, IGF1, HSP90AA1, SOD1, SOCS3, MAP2K7, MSTN, TGFB1I1, IL1B, IL6, HSF1, MICA, P2RX3, SST, MICB, CPB2 |
response to hepatocyte growth factor | biological_process | PLAU |
response to herbicide | biological_process | STAR, CYP17A1, CYP1A1 |
response to high density lipoprotein particle | biological_process | ADAM17 |
response to histamine | biological_process | DRD2 |
response to hormone | biological_process | GCLC, PLA2G4A, AKT1, CTNNB1, LIPC, TIMP2, MMP14, TACR1, MDK, TIMP3, INSR, ANG, ANXA1, TIMP1, SOCS3, GHRL, ESR2, SFRP4, TIMP4, RERG, PIAS3 |
response to human chorionic gonadotropin | biological_process | ESR2 |
response to hydrogen peroxide | biological_process | BCL2, SRC, PLA2G4A, SHC1, CASP3, HMOX1, SDC1, STAR, JUN, CRYAB, SOD1, GPX1, HP, ADA, CAT, RELA, PARK7, SIRT1 |
response to hydroperoxide | biological_process | GPX1 |
response to hydrostatic pressure | biological_process | COL18A1 |
response to hyperoxia | biological_process | WNT5A, CDKN1A, PLAU, CAT, CYP1A1, HDAC2, AGER |
response to hypoxia | biological_process | VEGFA, NOS2, MMP13, LEP, SHC1, MTHFR, SLC6A4, CASP1, CDKN1B, DRD2, CASP3, XRCC1, ENG, EDNRA, ITGA2, FLT1, HMOX1, USF1, LIPC, FAS, CCL2, VCAM1, MMP14, ARNT, HMOX2, ADM, CXCL12, IGF1, ANG, CRYAB, TGFB1, ACTN4, PLAT, PRKCB, PDGFA, SOCS3, ANGPT2, CLDN3, THBS1, FIGF, IL1B, PLAU, ADA, LTA, ICAM1, CAT, CYP1A1, EDN1, MMP2, TGFB2, SMAD3, HIF1A, CXCR4, TEK, PAK1, ADIPOQ, PPARA, ATM, SMAD4, ADAM17, DNMT3B, CX3CL1, P2RX3, HSD11B2, POSTN |
response to immobilization stress | biological_process | PPARG, CYP1A2, FOS, CYP1A1, CRH, UCN2 |
response to inactivity | biological_process | IL10, DRD2, CAT |
response to inorganic substance | biological_process | LIPC, FAS, PDGFA, TNFRSF11B, PTEN, RELA |
response to insecticide | biological_process | STAR, CYP17A1, ESR2 |
response to insulin | biological_process | GSK3B, EGR1, CCL5, IL10, LEP, SHC1, MTOR, ADM, INSR, SOCS3, CAT, IL6, RELA, FOXO1, PPARA, SIRT1, HSD11B2, RETN |
response to insulin-like growth factor stimulus | biological_process | GSK3B, AKT1 |
response to interferon-gamma | biological_process | CXCL16 |
response to interleukin-1 | biological_process | SRC, CHI3L1, MTHFR, PTGER4, IL1R1, SELE, ANXA1, LGALS9, FIGF, RELA |
response to interleukin-13 | biological_process | CCL11 |
response to interleukin-4 | biological_process | CTSB, CCL11 |
response to interleukin-6 | biological_process | CHI3L1 |
response to ionizing radiation | biological_process | H2AFX, DNMT1, BRCA1, VCAM1, CCR2, STAR, XRCC3, CYP17A1, ICAM1, DNMT3A, BAX, ATM, DNMT3B |
response to iron ion | biological_process | BCL2, CCND1, DRD2, BMP6, ABCG2, HAMP |
response to iron(III) ion | biological_process | CYP1A1, ATP7A |
response to ischemia | biological_process | BCL2, UCHL1, FN1, EIF4EBP1 |
response to kainic acid | biological_process | PTN |
response to L-ascorbic acid | biological_process | ITGA2, SPARC, GSTP1, IL1B, CAT |
response to L-glutamate | biological_process | GSK3B |
response to laminar fluid shear stress | biological_process | TGFB1, SMAD7 |
response to lead ion | biological_process | DNMT1, SPARC, STAR, CAT, DNMT3A |
response to leptin | biological_process | CCND1, STAT3, LEPR, STAR, EDN1, SIRT1 |
response to light intensity | biological_process | CAT |
response to light stimulus | biological_process | CLU, DRD2, CLOCK, FOS, NTRK2, OGG1 |
response to linoleic acid | biological_process | CD36, ADIPOQ |
response to lipid | biological_process | PCNA, PPARG, CD36, BRCA1, GATA2, LIPC |
response to lipid hydroperoxide | biological_process | GPX3 |
response to lipopolysaccharide | biological_process | NOS2, DNMT1, PLA2G4A, F2R, TNFRSF1A, CCL5, MAPK1, F3, IL10, OPRM1, PTGER4, CASP1, NOTCH1, CASP3, FASLG, TNFRSF1B, CD40, EDNRA, SPARC, CXCL1, FAS, CCL2, IDO1, VCAM1, SELP, SELE, CXCL2, COMT, IL12A, IL13, ADM, PTGS2, CCR2, CXCL5, PTGFR, PTGER2, IGF1, JUN, CXCL10, LGALS9, PTGES, TLR4, CYP1A2, TNFRSF11B, SOCS3, FOS, SLPI, CXCL13, TNFRSF21, IL1B, LTA, ICAM1, CYP1A1, MPO, IL6, EDN1, CTSG, HDAC2, RELA, FOXP1, HSF1, NFKB2, PTPN22, ADAM17, CXCL6, LOXL1, TIMP4, DCN, CCR7 |
response to lithium ion | biological_process | GSK3B, PLA2G4A, IGFBP2, PTGS2 |
response to low-density lipoprotein particle | biological_process | PPARG, F3 |
response to magnesium ion | biological_process | CCND1, LIPC, BMP6, C3, TNFRSF11B, THBS1 |
response to manganese ion | biological_process | PTGS2, INSR |
response to mechanical stimulus | biological_process | SRC, BMP4, PPARG, MMP13, IGFBP2, CHI3L1, F3, CCNB1, PTGER4, CCL2, MMP14, TNC, IL13, TIMP3, CXCL12, IGF1, JUN, FOS, ANGPT2, CTSB, MPO, IL6, RELA, HIF1A, P2RX3, POSTN, RETN, DCN |
response to mercury ion | biological_process | GSTP1, BSG |
response to metal ion | biological_process | CASP3 |
response to metformin | biological_process | PPARG |
response to methylglyoxal | biological_process | AGER |
response to methylmercury | biological_process | PLA2G4A, CYP17A1 |
response to mineralocorticoid | biological_process | SRC, KRAS |
response to misfolded protein | biological_process | CLU |
response to molecule of bacterial origin | biological_process | IL10, CXCL8, CXCL2, TLR2, TLR9 |
response to morphine | biological_process | OPRM1, DRD2, EDNRA, TACR1, MTOR, FGA, IL1B, ADA, RELA |
response to muramyl dipeptide | biological_process | NOTCH1, RELA, NOD2, JAG1 |
response to muscle activity | biological_process | ITGA2, MSTN, HIF1A, POSTN, SRD5A1 |
response to muscle stretch | biological_process | NFKB1, JUN, FOS, EDN1, RELA |
response to nematode | biological_process | CYP1A1 |
response to nerve growth factor | biological_process | PTN |
response to nicotine | biological_process | BCL2, SHC1, DRD2, CASP3, HMOX1, VCAM1, TACR1, IL13, STAR, IGF1, IGF2, EDN1, HDAC2 |
response to nitric oxide | biological_process | BMP4, IL1R1, CCL19, CCR7 |
response to nitrosative stress | biological_process | GCLC |
response to nutrient | biological_process | PPARG, IGFBP2, LEP, BRCA1, SLC6A4, BRCA2, VCAM1, MTOR, SSTR1, AKR1C3, STAR, IGF1, APOA1, BCHE, TNFRSF11B, IL1B, CP, LTA, IL4, PTEN, ADIPOQ, SST, DAD1, ADIPOR2, PEMT |
response to nutrient levels | biological_process | SRC, DNMT1, CCL5, LEP, GSTP1, MMP7, LIPC, IL15, PON1, SRD5A2, STAR, INSR, IGF1, ITGB1, CYP17A1, SOD1, IGF2, GC, IL6, DNMT3A, ADIPOQ, ESR2, PAX2 |
response to organic cyclic compound | biological_process | CCND1, STAT3, BMP4, WNT5A, PPARG, CCL5, SHC1, CTNNB1, PTGER4, NFKB1, AHR, CDKN1B, ID1, CASP3, CDKN1A, CTNNA1, EDNRA, ITGA2, STS, LIPC, LIFR, MMP14, SELP, TACR1, HNF1B, COMT, OXTR, SRD5A2, PTGS2, TIMP3, MMP12, STAR, MKI67, IGF1, CYP17A1, JUN, TGFB1, ANXA1, PTGES, CYP1A2, SOCS3, FOS, ANGPT2, CTSB, IL1B, IGF2, ICAM1, AMH, CYP1A1, IL4, IL6, EPHX1, PTEN, RELA, ESR2, SRD5A1, STC1, CD83, TET2 |
response to organic substance | biological_process | AKR1B1, CDH1, CCND1, STAT3, DNMT1, PLA2G4A, WNT5A, PPARG, IL10, IL12B, ANXA5, AKT1, BRCA1, SLC6A4, CASP3, SPP1, CDKN1A, XRCC1, S100P, SDC1, SRD5A2, ADM, PTGS2, TIMP3, STAR, XRCC3, IGF1, CA2, CYP17A1, JUN, TGFB1, SOD1, TIMP1, TNF, PDGFA, CYP1A2, CYP1A1, PTEN, RELA, TEK, PAK1, P2RX3, TIMP4 |
response to organonitrogen compound | biological_process | CCND1, PLA2G4A, APEX1, CDKN1A, AGTR2, PTGS1, FLT3, PTGS2, CYP2E1, IL1B, SST |
response to organophosphorus | biological_process | AKR1C1 |
response to osmotic stress | biological_process | ATF2, MAP2K7 |
response to oxidative stress | biological_process | GCLC, BCL2, GPX3, AKT1, NFKB1, MBL2, HMOX1, MMP14, LPO, PTGS1, PTGS2, SOD1, APOE, GPX1, KRT1, CAT, MPO, PARK7, SIRT1, UCN, MICB, OGG1 |
response to ozone | biological_process | TACR1, FN1, CYP2E1, IL1B, CAT, EDN1 |
response to pain | biological_process | TACR1, COMT, SLC6A2, CRH, UCN |
response to parathyroid hormone | biological_process | ITGA2 |
response to peptide | biological_process | OXTR |
response to peptide hormone | biological_process | STAT3, GJA1, CDKN1B, BRAF, SPARC, STS, LIPC, FAS, OXTR, SRD5A2, BSG, STAR, CXCL12, ANXA1, TIMP1, SOCS3, CTSB, IL1B, TEK, TIMP4 |
response to peptidoglycan | biological_process | IL6 |
response to pH | biological_process | GJA1, STS, CA2 |
response to phenylpropanoid | biological_process | CAT |
response to potassium ion | biological_process | CLU |
response to progesterone | biological_process | PTGER4, CCL2, TACR1, PTN, OXTR, PTGER3, PTGER2, TGFB1, C3, CLDN4, SOCS3, FOS, THBS1, TGFB2, RELA |
response to prostaglandin E | biological_process | PTGER4, CCL21, CCL19, CCR7 |
response to prostaglandin F | biological_process | EDN1 |
response to purine-containing compound | biological_process | HIF1A |
response to radiation | biological_process | BCL2, TXN, KIT, OPRM1, IL1R1, PTGS2, CXCL12, JUN, TGFB1, ANGPT2, IGF2, CAT, BCL2L1, OGG1, CCL11 |
response to reactive oxygen species | biological_process | TXN, PRDX6, GPX3, GSTP1, ALDH3A2, SOD1, APOE, GPX1, CAT |
response to redox state | biological_process | CLOCK |
response to retinoic acid | biological_process | BMP4, PPARG, IGF2R, IGFBP2, BMP6, HSD17B2, CYP17A1, PDGFA, PTGES, DKK1, MICB |
response to salt | biological_process | PTGER4, PTGER3, EDN1, ESR2 |
response to salt stress | biological_process | CCL5, HSP90AA1, TNF, HIF1A, BAX |
response to selenite ion | biological_process | AGER |
response to selenium ion | biological_process | GPX1 |
response to starvation | biological_process | PPARG, SSTR1, ADM |
response to statin | biological_process | IL1B |
response to steroid hormone | biological_process | BCL2, CCND1, IGFBP2, SPP1, OXTR, SRD5A2, STAR, IGF1, CA2, CYP17A1, GC, SST, HSD11B2 |
response to stilbenoid | biological_process | CD36, IL1B |
response to stimulus | biological_process | CDH3, TIMP3, DLL4 |
response to stress | biological_process | AKR1B1, MAPK1, STIP1, MTOR, HSP90AA1, EGFR, SGK1, C5, ERRFI1, UCN2 |
response to sucrose | biological_process | ADIPOQ |
response to sulfur dioxide | biological_process | ICAM1 |
response to superoxide | biological_process | SOD1 |
response to symbiotic bacterium | biological_process | GPX1 |
response to temperature stimulus | biological_process | F3, P2RX3 |
response to testosterone | biological_process | BMP4, DNMT1, WNT5A, NME1, SRD5A2, INSR, MSTN, EDN1, ESR2, DEFB1, SRD5A1 |
response to thyroid hormone | biological_process | AKR1B1, ANXA5, ANXA2 |
response to toxic substance | biological_process | BCL2, CDH1, DNMT1, CCL5, MAPK1, SHC1, CCNB1, CCL3, SLC6A4, AHR, DRD2, CDKN1A, GSTP1, FAS, SDC1, PON1, STAR, CYP17A1, FOS, GPX1, CAT, CYP1A1, EPHX1, DNMT3A, BAX, DNMT3B, BLMH, CYP1B1 |
response to transforming growth factor beta | biological_process | IL1R1, ITGB1, EDN1, RUNX3, SMAD4 |
response to tumor necrosis factor | biological_process | CCL5, CHI3L1, CASP3, SELE, PTGS2, INSR, MAP2K7, ADIPOQ, CXCL16 |
response to ultrasound | biological_process | GSK3B |
response to unfolded protein | biological_process | HSPD1, HSPA6, HSPA4, HSP90AA1, HSPB1, THBS1, CREB3L1 |
response to UV | biological_process | MSH6, CASP3, CDKN1A, USF1, MAP2K7, CAT |
response to UV-A | biological_process | CCND1, AKT1, EGFR |
response to UV-B | biological_process | MSH2, BCL2, IL12B, IL12A, RELA |
response to UV-C | biological_process | BRCA2 |
response to virus | biological_process | SRC, GATA3, HMGA2, CCL5, CLU, CFL1, HMGA1, STMN1, IL12A, CXCL12, IFNG, TNF, CXCL10, HSPB1, ENO1, CCL22, TLR3, CYP1A1, BCL2L1, CXCR4, CCL19, FOXP3, MST1R, PIM2, ISG20, TBX21, CCL11, LILRB1 |
response to vitamin | biological_process | PEMT |
response to vitamin A | biological_process | DNMT1, PPARG, CAT, CYP1A1, DNMT3A, AGER, DNMT3B |
response to vitamin B2 | biological_process | MTHFR |
response to vitamin B3 | biological_process | CCL2 |
response to vitamin D | biological_process | PLA2G4A, SPP1, PTGS2, INSR, TGFB1, CXCL10, CD4, IL1B, STC1, CYP24A1 |
response to vitamin E | biological_process | CCND1, LEP, ADA, CAT |
response to water deprivation | biological_process | AKR1B1, ATF2, ESR2 |
response to water-immersion restraint stress | biological_process | PTGER4 |
response to wounding | biological_process | F2R, CLU, F3, CASP3, CCR1, CCL2, MDK, TNC, SOX2, ADM, CCR2, FN1, TGFB1, PDGFA, NRP1, CTSB, GPX1, WNT1, CYP1A1, IL6, RAC1, TGFB2, BAX, POU5F1, AGER |
response to X-ray | biological_process | MSH2, CCND1, CASP3, CDKN1A, BRCA2, ANXA1, TP53, XRCC4, HIF1A, TP63 |
response to xenobiotic stimulus | biological_process | GCLC, AHR, GPX1, AHRR |
response to yeast | biological_process | PTX3, ADM, ANG, MPO, IL6, NPY |
response to zinc ion | biological_process | VCAM1, CA2, PTEN, ATP7A |
retina development in camera-type eye | biological_process | BMP4, SERPINF1, LIF, PTN, BMPR1B, IL4, NTRK2, BAX, NECTIN1 |
retina homeostasis | biological_process | AZGP1, CDH3, SOD1, LTF, HSPB1, KRT1, TF, ACTB |
retina layer formation | biological_process | PROM1 |
retina morphogenesis in camera-type eye | biological_process | PROM1, NECTIN3 |
retina vasculature development in camera-type eye | biological_process | PDGFRA, HIF1A, CYP1B1 |
retina vasculature morphogenesis in camera-type eye | biological_process | NRP1 |
retinal blood vessel morphogenesis | biological_process | COL4A1, CYP1B1 |
retinal cell programmed cell death | biological_process | FASLG, BAX |
retinal ganglion cell axon guidance | biological_process | BMPR1B, NRP1 |
retinal metabolic process | biological_process | AKR1C3, AKR1C1, CYP1B1 |
retinal pigment epithelium development | biological_process | PAX2 |
retinal rod cell development | biological_process | NTRK2, NAGLU |
retinal rod cell differentiation | biological_process | PTN |
retinoic acid biosynthetic process | biological_process | RBP1 |
retinoic acid catabolic process | biological_process | CYP26A1 |
retinoic acid receptor signaling pathway | biological_process | ACTN4 |
retinoid metabolic process | biological_process | SDC4, RBP1, SDC1, AKR1C3, APOA1, APOA2, APOE, RARRES2, AKR1C1 |
retinol metabolic process | biological_process | AKR1C3, CYP1B1 |
retrograde axonal transport | biological_process | SOD1 |
retrograde transport, endosome to Golgi | biological_process | STX5 |
retrograde vesicle-mediated transport, Golgi to ER | biological_process | KIFAP3 |
reverse cholesterol transport | biological_process | CETP, CLU, LIPC, APOA1, APOA2, APOE, SCARB1 |
Rho protein signal transduction | biological_process | BCL6, CFL1, AGTR1, EDNRA, LIMK1, RHOA |
rhombomere 3 development | biological_process | HOXB2 |
rhombomere 4 development | biological_process | HOXB2 |
rhythmic excitation | biological_process | EDN1 |
rhythmic process | biological_process | GSK3B, PPARG, AHR, ID1, CLOCK, TP53, SUV39H1, HDAC2, PPARA, NFKB2, KAT2B, HDAC1, EZH2, SIRT1, ID2, TWIST1, KLF10, SUV39H2, KLF9 |
rhythmic synaptic transmission | biological_process | PTEN |
ribosome biogenesis | biological_process | C1QBP |
RNA biosynthetic process | biological_process | TERT |
RNA catabolic process | biological_process | ISG20 |
RNA destabilization | biological_process | TNFRSF1B |
RNA phosphodiester bond hydrolysis | biological_process | AZGP1, ANG |
RNA phosphodiester bond hydrolysis, endonucleolytic | biological_process | APEX1, DICER1 |
RNA phosphodiester bond hydrolysis, exonucleolytic | biological_process | ISG20 |
RNA processing | biological_process | DICER1 |
RNA splicing | biological_process | LGALS3, WT1, C1QBP, YBX1 |
RNA-dependent DNA biosynthetic process | biological_process | TERT |
rod bipolar cell differentiation | biological_process | PTN |
Roundabout signaling pathway | biological_process | RHOA |
rRNA processing | biological_process | SUV39H1, SIRT1, CDKN2A, RPL41, ISG20 |
rRNA transcription | biological_process | ANG |
ruffle assembly | biological_process | RAC1, AIF1 |
ruffle organization | biological_process | MTOR, CCL21, CSF1R, RAC1, CCR7 |
S-adenosylhomocysteine metabolic process | biological_process | DNMT1, DNMT3A, DNMT3B, PEMT |
S-adenosylmethioninamine metabolic process | biological_process | DNMT1, DNMT3A, DNMT3B |
S-adenosylmethionine biosynthetic process | biological_process | MAT2A |
S-adenosylmethionine metabolic process | biological_process | DNMT1, MTHFR, PEMT |
S-shaped body morphogenesis | biological_process | HES5 |
saliva secretion | biological_process | AQP5 |
salivary gland morphogenesis | biological_process | FGFR1, EGFR, TGFB1, TGFB2 |
sarcomere organization | biological_process | KRT19, ITGB1 |
Schwann cell differentiation | biological_process | ERBB3, ADAM22 |
Schwann cell proliferation | biological_process | CTNNB1 |
sebaceous gland development | biological_process | SMAD4 |
sebum secreting cell proliferation | biological_process | PRDM1 |
secondary heart field specification | biological_process | BMP4 |
secondary metabolite biosynthetic process | biological_process | CYP11A1 |
secretion | biological_process | CA2, PTGES2 |
secretion by cell | biological_process | AXL, TYRO3 |
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development | biological_process | NOTCH1 |
semaphorin-plexin signaling pathway | biological_process | MET, NRP1, RAC1, SEMA3A, SEMA3C |
semaphorin-plexin signaling pathway involved in axon guidance | biological_process | NRP1, SEMA3A |
semaphorin-plexin signaling pathway involved in neuron projection guidance | biological_process | NRP1, NRP2, SEMA3A |
semicircular canal development | biological_process | GATA2 |
semicircular canal morphogenesis | biological_process | ZEB1 |
seminiferous tubule development | biological_process | SMAD4 |
senescence-associated heterochromatin focus assembly | biological_process | HMGA2, HMGA1, CDKN2A |
sensory neuron axon guidance | biological_process | NRP1 |
sensory organ boundary specification | biological_process | NTF4 |
sensory perception | biological_process | OPRM1 |
sensory perception of mechanical stimulus | biological_process | IFNG |
sensory perception of pain | biological_process | MME, MAPK1, IL12B, OPRM1, UCHL1, EDNRA, TACR1, PTGS1, PTGS2, EDN1, CRHR2 |
sensory perception of smell | biological_process | DRD2 |
sensory perception of sound | biological_process | FGFR1, CDKN1B, CASP3, SOD1, SPRY2, GPX1, ICAM1, UCN |
sensory perception of taste | biological_process | CD36, P2RX3 |
sensory system development | biological_process | SEMA3A |
sequestering of triglyceride | biological_process | TNF, IL1B |
serine phosphorylation of STAT3 protein | biological_process | IL24 |
serotonin metabolic process | biological_process | MAOA, ATP7A, SRD5A1 |
serotonin secretion by platelet | biological_process | FCER1G |
serotonin transport | biological_process | SLC6A4 |
serotonin uptake | biological_process | SLC6A4 |
Sertoli cell development | biological_process | SDC1, ESR1, ESR2 |
Sertoli cell proliferation | biological_process | ESR1, FSHB, BAX, ESR2 |
sesquiterpenoid metabolic process | biological_process | ALDH3A2 |
sex determination | biological_process | WT1, AMH, SRD5A1 |
sex differentiation | biological_process | AR, SRD5A2, CYP17A1, WNT7A, AMH, BAX, AMHR2, WNT4, SRD5A1 |
sexual reproduction | biological_process | STAT3, IL12B, LEP, LEPR |
short-term memory | biological_process | SERPINF1, MDK, COMT |
signal complex assembly | biological_process | SRC, PTK2 |
signal peptide processing | biological_process | GAS6, PCSK5 |
signal transduction | biological_process | SRC, TXN, GATA3, FGF2, FSHR, MET, STAT3, NR2F2, CRHR1, F2R, PPARG, TNFRSF1A, MAPK1, IGF2R, IGFBP2, GJA1, PIK3R1, KIT, LEP, CXCL8, OPRM1, ANXA5, AKT1, SHC1, PTGER4, NFKB1, CASP1, AR, TNFSF10, ERBB3, DRD2, FPR1, PLCD1, RASSF2, FASLG, SDC4, CCR1, CCR5, CXCR3, CSF2RB, VDR, BRAF, AXL, AGTR1, AGTR2, ANXA4, FST, IGFBP5, IL6ST, EDNRA, CRHBP, SPARC, LGALS1, IGFBP1, CNTF, CXCL1, IL1R1, CXCR1, CXCR2, KITLG, PECAM1, FAS, CCL2, IL2RB, IL15, STMN1, STAT6, TACR2, TACR1, MDK, IGFBP4, LHCGR, MRC1, MTOR, FCER1G, OXTR, SSTR1, IL13, ADM, SSTR5, VEGFC, CCR2, CXCL5, PTGFR, PTGER3, PTGER2, KIR3DL1, CXCL12, CCR9, ESR1, IGF1, GREM1, HSP90AA1, EGFR, FGF1, CLOCK, ANXA1, MAP3K7, LGR5, FGA, IGF1R, PRKCB, INHA, S100A6, CXCL10, C3, PTGES, TLR2, TLR4, ERBB2, CD4, TNFRSF11B, CXCR6, CCL22, CLDN4, SOCS3, MAP2K7, NRP1, ANGPT2, TLR3, CAPN5, NR3C1, CLDN3, KALRN, TNFRSF21, NCR1, PGR, IL1B, DIRAS3, CXCL14, PAK4, EGF, PLAU, NRAS, KRAS, CGA, FSHB, LHB, LTA, CD74, RLN1, CRH, CSF1R, HIF1A, GAS6, TYRO3, DPYSL2, PLAUR, PLCB1, CXCR4, TEK, F2RL1, TLR9, ESR |
signal transduction by p53 class mediator | biological_process | CDKN1A, GREM1 |
signal transduction by protein phosphorylation | biological_process | KDR, INSR, BMPR1B, PAK4, TGFB2, TYRO3, PAK1, AMHR2 |
signal transduction in response to DNA damage | biological_process | CHEK2, WNT1 |
signal transduction involved in intra-S DNA damage checkpoint | biological_process | CHEK2 |
signal transduction involved in mitotic G2 DNA damage checkpoint | biological_process | ATM |
signal transduction involved in regulation of gene expression | biological_process | EPCAM, SMAD3, SMAD2 |
signaling | biological_process | CCL3, CCR5 |
single fertilization | biological_process | HOXA10, HOXA11, FOXL2, PARK7, MST1R, SMAD4, IGSF8, OVGP1 |
single organismal cell-cell adhesion | biological_process | BCL2, SRC, CDH1, SHC1, CTNNB1, CD44, VCAM1, SELP, CDH3, EGFR, CYR61, ITGB2, ICAM1, CDC42, NECTIN1, NECTIN3, ADAM8, VEZT |
single strand break repair | biological_process | XRCC1, SIRT1 |
single-organism behavior | biological_process | ITGA3 |
siRNA loading onto RISC involved in RNA interference | biological_process | DICER1 |
sister chromatid biorientation | biological_process | RB1 |
sister chromatid cohesion | biological_process | BIRC5, PLK1 |
sister chromatid segregation | biological_process | LATS1 |
skeletal muscle atrophy | biological_process | IL15, MSTN |
skeletal muscle cell differentiation | biological_process | EGR1, NOTCH1, RB1, FOS |
skeletal muscle contraction | biological_process | HSP90AA1 |
skeletal muscle fiber development | biological_process | GPX1 |
skeletal muscle satellite cell activation | biological_process | WNT7A |
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration | biological_process | IGF1, WNT7A, EZH2 |
skeletal muscle satellite cell migration | biological_process | RHOC, RHOA |
skeletal muscle tissue development | biological_process | NR2F2, CTSB, CSF1R, IGSF8, DCN |
skeletal muscle tissue growth | biological_process | IGFBP5, CRHR2 |
skeletal muscle tissue regeneration | biological_process | GJA1, SOX15, MSTN, GPX1, PLAU |
skeletal system development | biological_process | FGFR1, BMP4, MMP9, CTNNB1, RASSF2, VDR, VCAN, HOXA10, BMP6, IGFBP4, HOXA11, PRELP, IGF1, INHA, AHSG, BMPR1B, TNFRSF11B, IGF2, EDN1, COL5A2, TGFB2, SMAD3, TP63, KLF10, DLX5, IHH, POSTN |
skeletal system morphogenesis | biological_process | FGFR1, FGFR2, HOXB2, MMP2 |
skin development | biological_process | ITGA6, ITGA3, CTNNB1, STS, PDGFA, COL5A2, ATP7A |
skin morphogenesis | biological_process | ITGA2, ERRFI1, TP63 |
sleep | biological_process | OXTR, FOS, IL18 |
SMAD protein complex assembly | biological_process | TGFB1, SMAD3, SMAD2, SMAD4 |
SMAD protein import into nucleus | biological_process | TOB1, JUN, TGFB1, TGFB2 |
SMAD protein signal transduction | biological_process | INHBA, BMP4, VIM, BMP6, JUN, TGFB1, INHA, MSTN, FOS, GDF9, TGFB2, SMAD3, SMAD2, SMAD4, NODAL, GDF15 |
small GTPase mediated signal transduction | biological_process | HMOX1, RHOC, DIRAS3, NRAS, KRAS, CDC42, RAC1, RND3, RHOA, RERG |
smooth muscle adaptation | biological_process | IL1B |
smooth muscle cell differentiation | biological_process | BMP4, CTNNB1, GATA6, WNT4 |
smooth muscle cell migration | biological_process | ITGB3, PLAT, PLAU |
smooth muscle cell proliferation | biological_process | EDNRA |
smooth muscle contraction | biological_process | EDNRA |
smooth muscle contraction involved in micturition | biological_process | TACR1 |
smooth muscle hyperplasia | biological_process | HMOX1, NOS3 |
smooth muscle tissue development | biological_process | BMP4, ENG, TP63 |
smoothened signaling pathway | biological_process | BMP4, HES5, IHH |
social behavior | biological_process | SLC6A4, MTOR, OXTR, IL1B, KRAS, PTEN, UCN |
sodium ion transport | biological_process | SGK1 |
sodium-independent organic anion transport | biological_process | SLCO2A1, SLCO4A1 |
somatic hypermutation of immunoglobulin genes | biological_process | MSH2, MSH6, MLH1, PMS2 |
somatic recombination of immunoglobulin gene segments | biological_process | MSH2, MSH6, MLH1 |
somatic recombination of immunoglobulin genes involved in immune response | biological_process | MSH2, MLH1 |
somatic stem cell division | biological_process | KIT, NOTCH1, WNT7A, TGFB2, CDKN2A |
somatic stem cell population maintenance | biological_process | YAP1, FGF2, STAT3, KIT, BRAF, GATA2, TDGF1, SOX2, WNT7A, SMAD2, POU5F1, SMAD4, KLF10, NANOG |
somatostatin signaling pathway | biological_process | SSTR1, SSTR5 |
somatotropin secreting cell differentiation | biological_process | WNT4 |
somite development | biological_process | WNT5A, IHH |
somite rostral/caudal axis specification | biological_process | SMAD4 |
somitogenesis | biological_process | WNT5A, SMAD3, ATM, SEMA3C |
sorbitol biosynthetic process | biological_process | AKR1B1 |
specification of animal organ position | biological_process | BMP4 |
specification of loop of Henle identity | biological_process | HES5 |
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway | biological_process | BMP4 |
Spemann organizer formation | biological_process | WNT1 |
sperm capacitation | biological_process | CFTR, SLC26A8 |
sperm ejaculation | biological_process | SLC6A4, TACR1, OXTR |
spermatid development | biological_process | KIT, PRM1, NECTIN3 |
spermatid differentiation | biological_process | BAX |
spermatogenesis | biological_process | H2AFX, MLH1, FSHR, BCL6, IGF2R, KIT, CCNB1, NOTCH1, ACE, AXL, BRCA2, FAS, HOXA10, SSTR1, HOXA11, CLOCK, SOD1, FSTL3, BCL2L11, CTSB, KHDRBS3, PLAU, PRM1, BCL2L1, DNMT3A, TYRO3, BAX, HSF1, SIRT1, SMAD4, CADM1, TP63, SLC26A8, PAFAH1B2, DNMT3L, WFDC2, CHD5 |
spermatogenesis, exchange of chromosomal proteins | biological_process | CHD5 |
sphingolipid biosynthetic process | biological_process | ALDH3A2, SGPP2 |
sphingolipid metabolic process | biological_process | PSAP, SMPD3 |
sphingomyelin catabolic process | biological_process | SMPD3 |
sphingomyelin metabolic process | biological_process | SMPD3 |
sphingosine metabolic process | biological_process | SGPP2 |
spinal cord association neuron differentiation | biological_process | WNT1 |
spinal cord development | biological_process | AKT1, PTN, MTOR, DPYSL2, SRD5A1 |
spindle assembly involved in female meiosis I | biological_process | AURKA |
spindle checkpoint | biological_process | BIRC5 |
spindle organization | biological_process | AURKA |
spleen development | biological_process | BCL2, FAS, BCL2L11, NFKB2, ADAM17, TET2 |
spongiotrophoblast differentiation | biological_process | LIF, SOCS3 |
spongiotrophoblast layer development | biological_process | ADM |
sprouting angiogenesis | biological_process | NOTCH1, FLT4, NRP1, THBS1, CDC42, TEK, ANGPT1 |
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development | biological_process | FGFR2, TP63 |
SRP-dependent cotranslational protein targeting to membrane | biological_process | RPL41 |
startle response | biological_process | DRD2, NRG1, UCN |
STAT protein import into nucleus | biological_process | F2R, EGF |
stem cell development | biological_process | WNT7A |
stem cell differentiation | biological_process | HMGA2, KIT, EPCAM, LIF, A2M, PAX2 |
stem cell population maintenance | biological_process | FGFR1, STAT3, KIT, CTNNB1, LIF, NODAL, NANOG, TET1 |
stem cell proliferation | biological_process | ABCB1 |
steroid biosynthetic process | biological_process | CYP19A1, PRLR, HSD3B2, HSD17B1, SRD5A2, HSD17B3, HSD17B2, STAR, CYP17A1, CYP11A1, HSD17B7, SRD5A1 |
steroid catabolic process | biological_process | STS, SRD5A2, CYP1A2 |
steroid hormone mediated signaling pathway | biological_process | NR2F2, BMP4, PPARG, AR, VDR, ESR1, NR5A2, PGRMC2, NR3C1, PGR, NR5A1, ESR2, PPARA, GPER1, NR0B2 |
steroid hormone receptor complex assembly | biological_process | FKBP4 |
steroid metabolic process | biological_process | AKR1D1, CETP, CYP2A6, STS, CYP2B6, SRD5A2, CYP2C19, AKR1C3, AKR1C2, CYP17A1, CYP2E1, CYP11A1, APOA1, APOE, CYP1A2, CRH, CYP1B1, SRD5A1, SULT1E1 |
sterol metabolic process | biological_process | CYP19A1, CYP17A1, CYP11A1, CYP1B1 |
stimulatory C-type lectin receptor signaling pathway | biological_process | SRC, NFKB1, FCER1G, PSMD9, MAP3K7, FYN, PSMD10, NRAS, KRAS, RELA, PAK1, KLRK1 |
strand displacement | biological_process | BRCA1, BRCA2, XRCC3, ATM |
strand invasion | biological_process | XRCC3 |
stress fiber assembly | biological_process | SRC, ITGB5, ITGB1, RHOA |
stress-activated MAPK cascade | biological_process | NFKB1, CRYAB, MAP3K7, MAP2K7 |
stress-activated protein kinase signaling cascade | biological_process | AKR1B1 |
stress-induced mitochondrial fusion | biological_process | STOML2 |
stress-induced premature senescence | biological_process | CDKN1A, SIRT1 |
striatal medium spiny neuron differentiation | biological_process | INHBA |
striated muscle cell development | biological_process | SDC1 |
striated muscle cell differentiation | biological_process | AKT1, IGFBP5, RB1, KRAS |
striated muscle contraction | biological_process | ARG2 |
striatum development | biological_process | DRD2 |
submandibular salivary gland formation | biological_process | CDC42 |
substantia nigra development | biological_process | CDC42, ACTB, YWHAH, RHOA |
substrate adhesion-dependent cell spreading | biological_process | SRC, AXL, EFNA1, FN1, ITGB3, ITGAV, LAMA5, RAC1, TYRO3, TEK, LAMC1 |
substrate-dependent cell migration | biological_process | ITGA2, VEGFC |
suckling behavior | biological_process | OXTR |
sulfate assimilation | biological_process | TXN |
sulfate transmembrane transport | biological_process | SLC26A8 |
sulfate transport | biological_process | SLC26A8 |
sulfation | biological_process | SULT1E1 |
sulfur amino acid metabolic process | biological_process | GCLC |
sulfur compound metabolic process | biological_process | CHST6, CHST2 |
superior temporal gyrus development | biological_process | GSK3B |
superoxide anion generation | biological_process | SOD1, EDN1 |
superoxide metabolic process | biological_process | NOS2, SOD1 |
suppression by virus of host apoptotic process | biological_process | BCL2L1 |
surfactant homeostasis | biological_process | VEGFA, PLA2G4A |
susceptibility to natural killer cell mediated cytotoxicity | biological_process | CADM1 |
swimming behavior | biological_process | IDO1 |
sympathetic ganglion development | biological_process | CTNNB1, NRP1, NRP2, SEMA3A |
sympathetic nervous system development | biological_process | GATA3, NRP1, TP63, SEMA3A |
sympathetic neuron projection extension | biological_process | NRP1, NRP2, SEMA3A |
sympathetic neuron projection guidance | biological_process | NRP1, NRP2, SEMA3A |
synapse assembly | biological_process | CDH1, WNT5A, DRD2, BDNF, WNT7A, PTEN, NRG1, SPOCK2 |
synapse maturation | biological_process | PTEN |
synapse organization | biological_process | CTNNB1, WNT7A, SNCG |
synapsis | biological_process | MLH1 |
synaptic transmission, cholinergic | biological_process | APOE, HRH4 |
synaptic transmission, dopaminergic | biological_process | DRD2, CRHBP, CRH, PARK7 |
synaptic transmission, GABAergic | biological_process | RAC1 |
synaptic vesicle maturation | biological_process | SYP |
synaptic vesicle membrane organization | biological_process | SYP |
synaptic vesicle recycling | biological_process | WNT7A |
synaptic vesicle transport | biological_process | CTNNB1, DPYSL2 |
synaptonemal complex disassembly | biological_process | PLK1 |
syncytium formation | biological_process | ERVW-1 |
T cell activation | biological_process | HSPD1, PRLR, TGFB1, CD4, FYN, ADA, IL6, SMAD3, FOXP3 |
T cell activation involved in immune response | biological_process | F2RL1 |
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological_process | ICAM1 |
T cell antigen processing and presentation | biological_process | ICAM1 |
T cell apoptotic process | biological_process | FASLG |
T cell chemotaxis | biological_process | CCL3, CXCR3, CXCL10, CXCL16 |
T cell costimulation | biological_process | SRC, CD40LG, PIK3R1, AKT1, HLA-DRB1, LGALS1, CTLA4, PIK3CA, MTOR, CD4, FYN, CCL21, HLA-DQA1, HLA-DPB1, CDC42, RAC1, PAK1, CCL19, HLA-DRA, KLRK1 |
T cell differentiation | biological_process | BCL2, EGR1, GATA3, KIT, LEP, CTNNB1, LEPR, TGFB1, CD4, PTPN22, DLL4, IL2, TBX21 |
T cell differentiation in thymus | biological_process | BCL2, GATA3, CTNNB1, WNT1, ADAM17, WNT4 |
T cell differentiation involved in immune response | biological_process | FCER1G |
T cell homeostasis | biological_process | BCL2, CASP3, FAS, TGFB1, BCL2L11, IL2RA, FOXP3 |
T cell homeostatic proliferation | biological_process | BAX |
T cell lineage commitment | biological_process | BCL2 |
T cell mediated cytotoxicity | biological_process | CADM1, MICA, MICB |
T cell mediated immunity | biological_process | FOXP3, JAG1 |
T cell proliferation | biological_process | IL23A |
T cell proliferation involved in immune response | biological_process | LILRB1 |
T cell receptor signaling pathway | biological_process | GATA3, MAPK1, PIK3R1, NFKB1, HLA-DRB1, PIK3CA, PSMD9, IFNG, MAP3K7, CD4, FYN, TNFRSF21, PSMD10, HLA-DQA1, HLA-DPB1, PTEN, RELA, PAK1, STOML2, FOXP3, HLA-DRA |
T cell selection | biological_process | CD4, CD74 |
T follicular helper cell differentiation | biological_process | FOXP1 |
t-circle formation | biological_process | XRCC3 |
T-helper 1 cell activation | biological_process | HMGB1 |
T-helper 1 cell differentiation | biological_process | HMGB1 |
T-helper 1 cell lineage commitment | biological_process | STAT6, IL4 |
T-helper 1 type immune response | biological_process | IL12B, HLA-DRB1, TLR4, IL18 |
T-helper 17 cell chemotaxis | biological_process | CCR2 |
T-helper 17 cell lineage commitment | biological_process | IL6 |
T-helper 2 cell cytokine production | biological_process | IL4 |
T-helper 2 cell differentiation | biological_process | GATA3, IL4 |
T-helper cell differentiation | biological_process | IL12B, PTGER4, ATP7A |
tachykinin receptor signaling pathway | biological_process | TACR2, TACR1 |
targeting of mRNA for destruction involved in RNA interference | biological_process | DICER1 |
taste bud development | biological_process | NTF4 |
telencephalon cell migration | biological_process | CXCL12, CXCR4 |
telencephalon development | biological_process | BMP4, FAS, OXTR, HES5 |
telencephalon regionalization | biological_process | BMP4 |
telomere capping | biological_process | HIST3H3 |
telomere maintenance | biological_process | PCNA, APEX1, TERT, ATM |
telomere maintenance via recombination | biological_process | PCNA, BRCA2, XRCC3 |
telomere maintenance via telomerase | biological_process | TERT, ATM |
temperature homeostasis | biological_process | STAT3, DRD2, GPX1, FOXO1 |
tendon cell differentiation | biological_process | BMP4 |
tertiary branching involved in mammary gland duct morphogenesis | biological_process | WNT4 |
testosterone biosynthetic process | biological_process | HSD17B1, HSD17B3, AKR1C3, STAR |
tetrahydrofolate interconversion | biological_process | MTHFR |
tetrahydrofolate metabolic process | biological_process | MTHFR |
thalamus development | biological_process | SLC6A4, PTN, SRD5A1 |
thermoception | biological_process | TRPV1 |
thigmotaxis | biological_process | ID2 |
thiocyanate metabolic process | biological_process | LPO |
thorax and anterior abdomen determination | biological_process | WT1 |
thrombin-activated receptor signaling pathway | biological_process | F2R, HPGD, F2RL1 |
thymic T cell selection | biological_process | GATA3 |
thymocyte apoptotic process | biological_process | BCL2L11, BAX |
thymus development | biological_process | BCL2, GATA3, MAPK1, CTNNB1, BRAF, SOD1, BCL2L11 |
thyroid gland development | biological_process | MAPK1, BRAF, SMAD3 |
thyroid hormone metabolic process | biological_process | SLCO4A1 |
thyroid hormone transport | biological_process | SLCO4A1 |
thyroid-stimulating hormone-secreting cell differentiation | biological_process | WNT4 |
Tie signaling pathway | biological_process | ANGPT2, TEK, ANGPT1 |
tissue development | biological_process | BMP4, GATA2, WT1, NR5A2, NR5A1, POSTN |
tissue homeostasis | biological_process | AKR1B1, ITGB1 |
tissue morphogenesis | biological_process | SMAD4, NODAL |
tissue regeneration | biological_process | CCNB1, NOTCH1, IGFBP1, SOX2, TIMP3 |
tissue remodeling | biological_process | MMP14, IL23A |
tolerance induction | biological_process | C3, FOXP3 |
tolerance induction to self antigen | biological_process | TGFB1, FOXP3 |
toll-like receptor 2 signaling pathway | biological_process | LGALS9, TLR2 |
toll-like receptor 3 signaling pathway | biological_process | TLR3 |
toll-like receptor 4 signaling pathway | biological_process | LGALS9, TLR4, ITGB2 |
toll-like receptor 9 signaling pathway | biological_process | TLR9 |
toll-like receptor signaling pathway | biological_process | TLR2, TLR4, TLR3, CTSB, TLR9 |
toll-like receptor TLR1:TLR2 signaling pathway | biological_process | TLR2 |
toll-like receptor TLR6:TLR2 signaling pathway | biological_process | CD36, TLR2 |
tongue morphogenesis | biological_process | BMP4 |
TOR signaling | biological_process | GATA3, MTOR, EIF4EBP1 |
toxin biosynthetic process | biological_process | CYP1A2 |
toxin metabolic process | biological_process | CYP1A2, CYP1A1, CYP1B1 |
toxin transport | biological_process | CASP1, ARID1A, NRP1 |
trabecula morphogenesis | biological_process | RHOA |
trabecular meshwork development | biological_process | CYP1B1 |
trachea development | biological_process | BMP4 |
trachea formation | biological_process | BMP4, MAPK1, CTNNB1 |
trachea morphogenesis | biological_process | CTNNB1 |
transcription from RNA polymerase II promoter | biological_process | EGR1, GATA3, STAT3, CDX1, HMGA2, ATF2, NFKB1, HMGA1, AHR, NOTCH1, GATA2, USF1, HOXA10, WT1, SOX2, ESR1, JUN, CLOCK, TP53, MYC, MEIS1, NR5A2, KLF11, FOS, TGFB1I1, NR3C1, COPS5, RUNX3, YBX1, RELA, FOXL2, HIF1A, NR5A1, SMAD2, NFE2L2, PPARA, NFKB2, POU5F1, SMAD4, TP63, GATA6, PAX2, USF2, DLX5, GATA5, MAF, CREB3L1 |
transcription initiation from RNA polymerase II promoter | biological_process | YAP1, PPARG, AR, NOTCH1, VDR, ESR1, NR5A2, NR3C1, PGR, NR5A1, ESR2, PPARA, KAT2B, NR0B2, NOTCH4 |
transcription, DNA-templated | biological_process | FGFR1, EGR1, TXN, GATA3, YAP1, CCND1, BCL6, STAT3, NR2F2, DNMT1, CDX1, HMGA2, PPARG, MAPK1, APEX1, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, AHR, NOTCH1, ID1, FASLG, VDR, COL4A2, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ZEB1, PTGER3, CHEK2, ESR1, JUN, CLOCK, MAP3K7, PRKCB, FSTL3, LTF, TP53, SUV39H1, MYC, BIRC5, ENO1, ERBB2, SMAD7, MEIS1, NR5A2, RB1, ARID1A, KLF11, NR3C1, KHDRBS3, PRDM1, PGR, IL33, C1QBP, RUNX3, YBX1, HDAC2, SMAD3, RELA, FOXL2, HIF1A, FOXP1, HES5, ATP1B4, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, NFKB2, POU5F1, KAT2B, HDAC1, FOXP3, EZH2, SIRT1, ID2, STAT4, SMAD4, TWIST1, NR0B2, ZNF366, CDKN2A, TP63, KLF10, GATA6, NAA15, SUV39H2, PAX2, USF2, DLX5, KLF9, IL16, PPRC1, TBPL2, NOTCH4, CHD5, NANOG, GATA5, TBX21, AHRR, MAF, FHIT, TET1, CREB3L1, SRA1, MBD2, PIAS3 |
transcription, RNA-templated | biological_process | TERT |
transcription-coupled nucleotide-excision repair | biological_process | PCNA, XRCC1, COPS5 |
transcytosis | biological_process | SRC |
transdifferentiation | biological_process | LIF, SMAD3, AGER |
transferrin transport | biological_process | TF |
transformation of host cell by virus | biological_process | INSR |
transforming growth factor beta receptor signaling pathway | biological_process | SRC, HPGD, ID1, ENG, ITGB5, CCL2, ITGB1, JUN, TGFB1, MAP3K7, APOA1, PDGFA, SMAD7, CLDN5, MSTN, FOS, GDF9, FSHB, TGFB2, PTK2, SMAD3, SMAD2, SMAD4, AMHR2, KLF10, GDF15, RHOA |
transforming growth factor beta receptor signaling pathway involved in primitive streak formation | biological_process | NODAL |
translation | biological_process | AKT1, COPS5, EIF3E, RPL41 |
translational initiation | biological_process | COPS5, EIF3E, RPL41 |
translesion synthesis | biological_process | PCNA |
transmembrane receptor protein serine/threonine kinase signaling pathway | biological_process | BMPR1B, AMHR2 |
transmembrane receptor protein tyrosine kinase signaling pathway | biological_process | MET, KIT, ERBB3, KDR, CSF1, FLT4, PDGFRA, JAK1, TYK2, FLT1, FLT3, NTF4, INSR, EGFR, IGF1R, NGF, ERBB2, CD4, FYN, CSF1R, NRG1, NTRK2, TEK, MST1R, ANGPT1 |
transmembrane receptor protein tyrosine phosphatase signaling pathway | biological_process | PTN |
transmembrane transport | biological_process | BCL2, GJA1, CFTR, SLC6A4, CLCN3, AZGP1, SLC6A2, APOA1, SLC22A23, ABCC4, ABCB1, SLC26A8, TRPV1 |
transmission of nerve impulse | biological_process | SOD1 |
transport | biological_process | ATP5A1, CETP, PTGDS, FOLR1, IGF2R, GJA1, CFTR, PIK3R1, CD36, AKT1, SLC6A4, AR, CLCN3, RBP1, PAEP, SLC6A2, AQP2, STAR, AFM, ATP5B, ACTN4, SERPINA6, APOA1, LTF, APOA2, APOE, SLC22A23, CCDC22, ABCC4, AQP8, CP, TF, GC, HPX, ABCB1, SYP, SMAD3, ATP1B4, S100A13, ATP7A, STX5, CSE1L, ABCG2, SLC26A8, TRPV1, AQP5, P2RX3, SLCO2A1, SLCO4A1, IPO13 |
TRIF-dependent toll-like receptor signaling pathway | biological_process | TLR4, TLR3 |
trigeminal ganglion development | biological_process | NRP1, SEMA3A |
trigeminal nerve morphogenesis | biological_process | NRP1 |
trigeminal nerve structural organization | biological_process | NRP1, SEMA3A |
triglyceride catabolic process | biological_process | LIPC, APOA1, APOE |
triglyceride homeostasis | biological_process | CETP, LIPC, APOA1, SCARB1 |
triglyceride metabolic process | biological_process | CETP, LIPC, CYP2E1, APOA2, APOE, GPX1, CAT |
triglyceride mobilization | biological_process | SIRT1 |
triglyceride transport | biological_process | CETP, CD36 |
triglyceride-rich lipoprotein particle remodeling | biological_process | APOA2 |
trophectodermal cell differentiation | biological_process | ADA, NODAL |
trophectodermal cellular morphogenesis | biological_process | NODAL |
trophoblast giant cell differentiation | biological_process | NR2F2, LIF, SOCS3, SNAI1, PRDM1 |
tryptophan catabolic process | biological_process | IDO1 |
tryptophan catabolic process to kynurenine | biological_process | IDO1 |
tryptophan metabolic process | biological_process | ATP7A |
tube closure | biological_process | WNT5A |
tube development | biological_process | ITGB3 |
tube formation | biological_process | VEGFA, NOTCH1, BCL2L11 |
tube morphogenesis | biological_process | GATA6, WNT4 |
tubulin complex assembly | biological_process | CRYAB |
tumor necrosis factor production | biological_process | TLR9 |
tumor necrosis factor secretion | biological_process | HMGB1 |
tumor necrosis factor-mediated signaling pathway | biological_process | CD40LG, TNFRSF1A, TNFRSF1B, CD40, FAS, PSMD9, TNF, TNFRSF11B, TNFRSF21, PSMD10, LTA, TNFSF13B, ADAM17 |
type 2 immune response | biological_process | BCL6, IL10, IL33, IL4, IL18 |
type B pancreatic cell development | biological_process | BMP4, WNT5A, BMP6 |
type B pancreatic cell differentiation | biological_process | GATA6 |
type B pancreatic cell proliferation | biological_process | IGFBP3, IGFBP5, IGFBP4 |
type I interferon signaling pathway | biological_process | EGR1, JAK1, TYK2, HLA-C, HLA-E, HLA-G, HLA-A, HLA-B, ISG20 |
Type II pneumocyte differentiation | biological_process | GATA6 |
type IV hypersensitivity | biological_process | GATA3 |
tyrosine catabolic process | biological_process | GSTZ1 |
tyrosine phosphorylation of STAT protein | biological_process | F2R, LEP |
tyrosine phosphorylation of Stat3 protein | biological_process | LIF |
tyrosine phosphorylation of Stat5 protein | biological_process | IL15 |
ubiquitin-dependent protein catabolic process | biological_process | UCHL1, PSMD9 |
ubiquitin-dependent SMAD protein catabolic process | biological_process | TGFB1I1, WNT1 |
UDP-glucose catabolic process | biological_process | GALT |
umbilical cord morphogenesis | biological_process | HEY1 |
urate biosynthetic process | biological_process | PNP |
urate metabolic process | biological_process | ABCG2 |
urea cycle | biological_process | ARG2 |
ureter development | biological_process | PAX2 |
ureter epithelial cell differentiation | biological_process | BMP4 |
ureter maturation | biological_process | GATA3, PAX2 |
ureter smooth muscle cell differentiation | biological_process | BMP4 |
ureteric bud development | biological_process | BCL2, FGFR1, BMP4, FGFR2, EPCAM, SDC4, SDC1, WT1, TGFB1, SMAD7, CAT, ARG2, SMAD3, SMAD2 |
ureteric bud elongation | biological_process | HNF1B |
ureteric bud formation | biological_process | GATA3, GREM1 |
urinary bladder development | biological_process | WNT5A, TP63 |
urinary bladder smooth muscle contraction | biological_process | PTGER3, P2RX3 |
urogenital system development | biological_process | GATA2, AMH, PAX2, SRD5A1 |
urokinase plasminogen activator signaling pathway | biological_process | PLAUR |
uterine wall breakdown | biological_process | TGFB2 |
uterus development | biological_process | SRC, GATA3, WNT5A, HOXA10, HOXA11, ESR1, WNT7A, FOXL2, SMAD4 |
uterus morphogenesis | biological_process | WNT7A |
UTP biosynthetic process | biological_process | NME1 |
UV protection | biological_process | GPX1, CAT |
UV-damage excision repair | biological_process | SIRT1 |
V(D)J recombination | biological_process | HMGB1, ATM |
vagina development | biological_process | WNT5A, AXL, ESR1, TYRO3, BAX |
vascular endothelial growth factor production | biological_process | HIF1A |
vascular endothelial growth factor receptor signaling pathway | biological_process | CRK, SRC, VEGFA, PIK3R1, KDR, FLT4, AXL, FLT1, CCL2, PIK3CA, VEGFC, ITGB3, HSP90AA1, ITGAV, HSPB1, FYN, NRP1, FIGF, NRP2, CDC42, RAC1, PTK2, ACTB, RHOA |
vascular endothelial growth factor receptor-1 signaling pathway | biological_process | FLT1 |
vascular endothelial growth factor receptor-2 signaling pathway | biological_process | PDCD6 |
vascular endothelial growth factor signaling pathway | biological_process | VEGFA, FLT4, FLT1, FLT3, NRP1, NRP2 |
vascular smooth muscle cell development | biological_process | ADM |
vascular transport | biological_process | GJA1 |
vascular wound healing | biological_process | HPSE, ADIPOR2 |
vasculature development | biological_process | BMP4, CTNNB1, FLT4, PIK3CA, HIF1A, NODAL |
vasculogenesis | biological_process | YAP1, VEGFA, CTNNB1, KDR, ENG, WT1, ADM, PTK2, NTRK2 |
vasculogenesis involved in coronary vascular morphogenesis | biological_process | NOTCH1 |
vasoconstriction | biological_process | SLC6A4, EDNRA, EDN1 |
vasodilation | biological_process | APOE, GPX1 |
VEGF-activated neuropilin signaling pathway | biological_process | VEGFA, NRP1 |
VEGF-activated neuropilin signaling pathway involved in axon guidance | biological_process | NRP1 |
vein smooth muscle contraction | biological_process | EDN1 |
venous blood vessel morphogenesis | biological_process | ENG |
venous endothelial cell differentiation | biological_process | NOTCH1 |
ventral spinal cord interneuron differentiation | biological_process | GATA2 |
ventral spinal cord interneuron fate commitment | biological_process | DLL4 |
ventral trunk neural crest cell migration | biological_process | NRP1, SEMA3A |
ventricular cardiac muscle cell development | biological_process | CCNB1 |
ventricular cardiac muscle cell differentiation | biological_process | NRG1 |
ventricular cardiac muscle tissue morphogenesis | biological_process | FGFR2, SMAD7 |
ventricular septum development | biological_process | GATA3, CYR61, PRDM1 |
ventricular septum morphogenesis | biological_process | NOTCH1, SMAD7, HEY1 |
ventricular trabecula myocardium morphogenesis | biological_process | NOTCH1, NRG1, DLL4 |
ventricular zone neuroblast division | biological_process | FGFR1, FGFR2 |
very-low-density lipoprotein particle clearance | biological_process | APOE |
very-low-density lipoprotein particle remodeling | biological_process | CETP, LIPC, APOE |
vesicle docking | biological_process | STX5 |
vesicle docking involved in exocytosis | biological_process | CFTR |
vesicle fusion | biological_process | STX5 |
vesicle fusion with Golgi apparatus | biological_process | STX5 |
vesicle transport along actin filament | biological_process | ACTN4 |
vesicle-mediated transport | biological_process | KALRN, STX5 |
vestibulocochlear nerve formation | biological_process | PAX2 |
vestibulocochlear nerve structural organization | biological_process | NRP1 |
viral entry into host cell | biological_process | AXL, ITGA2, ITGB5, NCAM1, ITGB6, MRC1, ITGB3, ITGB1, ITGAV, CTSB, ICAM1, GAS6, TYRO3, NECTIN1, SCARB1, NECTIN4 |
viral genome replication | biological_process | CCL2, CXCR6, GAS6 |
viral life cycle | biological_process | PCSK5 |
viral process | biological_process | MSH6, H2AFX, HSPD1, SRC, STAT3, TNFRSF1A, FBLN1, MAPK1, PIK3R1, VIM, SHC1, HMGA1, KRT19, KDR, CCR5, PDGFRA, AXL, IL6ST, ITGA2, ITGB5, KRT7, HLA-C, NCAM1, IL2RB, VCAM1, ITGB6, MRC1, HLA-A, CCR2, ITGB3, ITGB1, ITGAV, TP53, SUV39H1, APOA2, CD4, FYN, RB1, HLA-B, ICAM1, HPX, MMP1, C1QBP, RELA, GAS6, TYRO3, BAX, CXCR4, SET, KAT2B, HDAC1, NECTIN1, SIRT1, SCARB1, MICA, IL16, NECTIN4, MICB, HLA-DRA, RHOA |
viral transcription | biological_process | RPL41 |
virion assembly | biological_process | APOE |
visceral serous pericardium development | biological_process | WT1 |
visual learning | biological_process | KIT, DRD2, BRAF, MTOR, ITGB1, SGK1, KRAS, HIF1A |
visual perception | biological_process | CDH3, TIMP3, COL18A1, PAX2, DLL4, CYP1B1 |
vitamin A metabolic process | biological_process | RBP1 |
vitamin D catabolic process | biological_process | CYP24A1 |
vitamin D metabolic process | biological_process | CYP11A1, GC, CYP1A1, CYP24A1 |
vitamin D receptor signaling pathway | biological_process | VDR, CYP24A1 |
vitamin metabolic process | biological_process | CYP26A1, CYP24A1 |
vitamin transmembrane transport | biological_process | SCARB1 |
vitamin transport | biological_process | AFM, APOA1, GC |
voluntary musculoskeletal movement | biological_process | MTOR |
water transport | biological_process | AQP2, AQP8, AQP5 |
white fat cell differentiation | biological_process | PPARG, SIRT1 |
Wnt signaling pathway | biological_process | GSK3B, CCND1, WNT5A, CTNNB1, WNT2, DRD2, WNT7A, TGFB1I1, DKK1, WNT1, WNT4, SFRP4 |
Wnt signaling pathway involved in dorsal/ventral axis specification | biological_process | EGF |
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological_process | WNT5A, WNT1 |
Wnt signaling pathway involved in somitogenesis | biological_process | DKK1 |
Wnt signaling pathway involved in wound healing, spreading of epidermal cells | biological_process | WNT7A |
Wnt signaling pathway, calcium modulating pathway | biological_process | WNT5A, CTNNB1, MAP3K7, PLCB1, PLCB3 |
Wnt signaling pathway, planar cell polarity pathway | biological_process | WNT5A, PSMD9, PSMD10, WNT1, CDC42, RAC1, RHOA |
wound healing | biological_process | FGF2, BMP4, WNT5A, ALOX15, OPRM1, ERBB3, CASP3, SDC4, PDGFRA, ENG, ITGA2, SPARC, SDC1, CDH3, TNC, MTOR, MMP12, FN1, ITGB3, TGFB1, TIMP1, PDGFA, ERBB2, WNT7A, IL1B, PLAU, IGF2, SERPINB2, IL6, TGFB2, SMAD3, NRG1, HPSE, PAK1, PPARA, IL24, SCARB1, CX3CL1, POSTN, DCN |
wound healing involved in inflammatory response | biological_process | HMOX1 |
wound healing, spreading of cells | biological_process | RHOC, CYR61, RHOA |
wound healing, spreading of epidermal cells | biological_process | MMP12, ADAM17 |
xanthine biosynthetic process | biological_process | ADA |
xanthine catabolic process | biological_process | XDH |
xenobiotic catabolic process | biological_process | GSTM1 |
xenobiotic metabolic process | biological_process | AHR, GSTP1, NAT2, CYP2B6, PTGS1, CYP2C19, CYP2E1, CYP1A2, EPHX1, AKR1C1, CYP1B1 |
xenobiotic transport | biological_process | ABCB1, ABCG2 |
xenophagy | biological_process | ANXA5, MSTN, CLDN7 |
zygotic specification of dorsal/ventral axis | biological_process | SMAD2 |
zymogen activation | biological_process | MMP14 |
A band | cellular_component | KAT2B |
acrosomal membrane | cellular_component | BSG |
acrosomal vesicle | cellular_component | KIT, NOTCH1, DRD2, CTNNA1, ITGB1, SPINK1, TRIM36, LOXL1, VEZT |
actin cap | cellular_component | CALD1 |
actin cytoskeleton | cellular_component | CRK, PGM1, CDH1, CFL1, CTNNA1, ACTN4, KALRN, STOML2, ADAM17, DAPK1, Sep-09, CALD1 |
actin filament | cellular_component | SRC, FYN, RAC1, TEK, AIF1 |
actin filament bundle | cellular_component | CRYAB |
activin A complex | cellular_component | INHBA |
activin responsive factor complex | cellular_component | SMAD2, SMAD4 |
actomyosin | cellular_component | KAT2B |
Ada2/Gcn5/Ada3 transcription activator complex | cellular_component | MAP3K7, KAT2B |
adherens junction | cellular_component | CTNNB1, NOTCH1, CTNNA1, ITGB1, NECTIN1, JAG1, NECTIN4, VEZT |
aggresome | cellular_component | CDH1, CLU |
AIM2 inflammasome complex | cellular_component | CASP1 |
alpha9-beta1 integrin-ADAM8 complex | cellular_component | ADAM8 |
alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex | cellular_component | VCAM1, ADAM8 |
alphav-beta3 integrin-IGF-1-IGF1R complex | cellular_component | IGF1, ITGB3, ITGAV, IGF1R |
alphav-beta3 integrin-vitronectin complex | cellular_component | ITGB3 |
anchored component of external side of plasma membrane | cellular_component | FOLR1 |
anchored component of membrane | cellular_component | FOLR1, TDGF1, NCAM1, EFNA1, PLAUR, ULBP2 |
anchored component of plasma membrane | cellular_component | FOLR1, EFNA1, CP, ULBP2 |
angiogenin-PRI complex | cellular_component | ANG |
AP-2 adaptor complex | cellular_component | EGFR |
apical cortex | cellular_component | HAMP |
apical dendrite | cellular_component | CLU, FAS |
apical junction complex | cellular_component | CDH1, CTNNB1, NECTIN3, RHOA |
apical part of cell | cellular_component | CD36, CTNNB1, VCAM1, CA2, PLAT, AQP8, CDC42, JAG1 |
apical plasma membrane | cellular_component | FOLR1, IGFBP2, GJA1, CFTR, CD36, EPCAM, ERBB3, NOTCH1, CLCN3, MUC1, IL6R, FAS, TDGF1, OXTR, AQP2, FN1, HSP90AA1, ANXA1, ERBB2, CLDN4, PROM1, CTSB, TF, PTEN, PTK2, NRG1, TEK, TLR9, NOD1, ADAM17, ABCG2, JAG1, AQP5, KISS1, MUC17, STC1 |
apicolateral plasma membrane | cellular_component | CLDN5, CLDN4, CLDN3, CLDN7 |
ARC complex | cellular_component | DICER1 |
aryl hydrocarbon receptor complex | cellular_component | AHR |
autophagosome | cellular_component | IL1B, GABARAPL1 |
autophagosome membrane | cellular_component | GABARAPL1 |
axolemma | cellular_component | NRG1 |
axon | cellular_component | GSK3B, MME, MAPK1, SERPINF1, DRD2, UCHL1, TNFRSF1B, ITGA2, CNTF, IL1R1, COMT, CA2, CYP17A1, TGFB1, NRP1, TNFRSF21, SNCG, GC, TGFB2, NRG1, DICER1, PARK7, NTRK2, DPYSL2, PAK1, GHRL, FKBP4, NECTIN1, AGER, GPER1, ADAM22, UCN, P2RX3, CRHR2, SEMA3A, CADM2, OLFM1, LPAR3 |
axon cytoplasm | cellular_component | UCHL1, SOD1, HIF1A |
axon hillock | cellular_component | SERPINF1, AURKA |
axon terminus | cellular_component | ANXA5, DRD2, ITGA2, CRHBP, CCL2, NTRK2, GPER1, UCN, CRHR2 |
axonal growth cone | cellular_component | L1CAM, FKBP4, LIMK1, OLFM1 |
axoneme | cellular_component | KIFAP3, Sep-09 |
azurophil granule | cellular_component | MPO, OLFM4 |
B cell receptor complex | cellular_component | CD79A |
BAF-type complex | cellular_component | ARID1A |
basal lamina | cellular_component | FN1, ANG, LAMA5 |
basal part of cell | cellular_component | ITGA6, ITGA2, TF, EDN1 |
basal plasma membrane | cellular_component | ITGA6, MET, CLDN4, TF, TEK, AGER, AQP5 |
basement membrane | cellular_component | ITGA6, FBLN1, SERPINF1, COL4A2, LAMA1, SPARC, PTN, TNC, TIMP3, COL18A1, FN1, ITGB1, TIMP1, LAMA5, ANXA2, COL4A1, LOXL1, LAMC2, SMOC2, NTN4, LAMC1 |
basolateral plasma membrane | cellular_component | ITGA6, ITGA3, FOLR1, CFTR, CTNNB1, HPGD, EPCAM, ERBB3, IL6R, LEPR, LPO, AQP2, CA2, HSP90AA1, EGFR, ANXA1, ERBB2, ABCC4, ANXA2, CLDN7, TEK, TLR9, NOD2, ATP7A, NOD1, CADM1 |
BAX complex | cellular_component | BAX |
Bcl-2 family protein complex | cellular_component | BCL2L1, BAX, MCL1 |
Bcl3/NF-kappaB2 complex | cellular_component | NFKB2 |
beta-catenin destruction complex | cellular_component | GSK3B, CTNNB1 |
beta-catenin-TCF complex | cellular_component | CTNNB1 |
beta-catenin-TCF7L2 complex | cellular_component | CTNNB1 |
bicellular tight junction | cellular_component | CCND1, CTNNB1, EPCAM, CLDN5, CLDN4, CLDN3, CLDN7 |
BIM-BCL-2 complex | cellular_component | BCL2L11 |
BIM-BCL-xl complex | cellular_component | BCL2L11 |
blood microparticle | cellular_component | CLU, HSPA6, C4A, PON1, AFM, FN1, TGFB1, A2M, FGA, AHSG, APOA1, BCHE, APOA2, APOE, C3, CP, HP, KRT1, TF, APCS, GC, HPX, C4BPA, A1BG, ACTB |
BRCA1-A complex | cellular_component | BRCA1 |
BRCA1-BARD1 complex | cellular_component | BRCA1 |
BRCA2-MAGE-D1 complex | cellular_component | BRCA2 |
brush border | cellular_component | MME, FOLR1, ACTN4 |
brush border membrane | cellular_component | FOLR1, CD36, PTGER3, HSP90AA1, ATP7A, PEMT |
C-fiber | cellular_component | CCL2 |
Cajal body | cellular_component | ISG20 |
catenin complex | cellular_component | CDH1, CTNNB1, CTNNA1, SMAD7, NECTIN1 |
catenin-TCF7L2 complex | cellular_component | CTNNB1 |
caveola | cellular_component | SRC, F2R, MAPK1, FASLG, HMOX1, SELE, NOS3, PTGS2, INSR, CTSB, SCARB1 |
CCR4-NOT complex | cellular_component | TOB1 |
CD40 receptor complex | cellular_component | CD40 |
CD95 death-inducing signaling complex | cellular_component | FAS |
cell | cellular_component | OPRM1, CXCL13, CCL19, CCL7, HAMP, CPB2, OLFM1, NPY |
cell body | cellular_component | GSK3B, BRAF, IL6ST, TACR1, COMT, NRG1, PARK7, GABARAPL1 |
cell body fiber | cellular_component | SRD5A2, CRHR2, SRD5A1 |
cell cortex | cellular_component | FGFR2, CTNNB1, FGF1, FGA, ANXA2, PTK2, LAMC2, RHOA |
cell junction | cellular_component | CDH1, ITGA3, GJA1, CTNNB1, EPCAM, KDR, CTNNA1, PECAM1, ITGB3, ITGB1, ACTN4, CLDN5, CLDN4, TGFB1I1, CLDN3, CLDN7, ADA, SYP, XRCC4, COPS5, PTK2, BCL2L1, PLAUR, CXCR4, TEK, PAK1, NECTIN1, GPER1, NECTIN3, CADM1, TRPV1, PTPRR, NECTIN4, CADM2, OLFM1, VEZT, RHOA |
cell leading edge | cellular_component | VIM, CXCR4 |
cell periphery | cellular_component | ITGA3, CTNNB1, KRT19, NOTCH1, TACR1, FYN, CDC42, RHOA |
cell pole | cellular_component | ASTN2 |
cell projection | cellular_component | ITGA3, VIM, ANXA5, CFL1, SPP1, S100P, ITGA2, MDK, L1CAM, AURKA, ITGB3, ITGB1, CYP17A1, ANXA1, ANGPT2, PROM1, SPRY2, CDC42, RAC1, PTEN, PLAUR, PAK1, AIF1, FKBP4, GPER1, ADAM22, TRPV1, CX3CL1, CADM2, OLFM1, RHOA |
cell projection cytoplasm | cellular_component | AKR1B1 |
cell projection membrane | cellular_component | CTNNB1 |
cell surface | cellular_component | HSPD1, ITGA6, VEGFA, MET, CD40LG, F2R, WNT5A, ITGA3, TNFRSF1A, FOLR1, FGFR2, IGF2R, HMGB1, CLU, CFTR, BGN, CD36, F3, DPP6, KIT, MIF, EPCAM, MBL2, NOTCH1, CLCN3, FASLG, SDC4, CCR5, CXCR3, CD40, AXL, ANXA4, ENG, PRLR, IL6R, ITGA2, ITGB5, SPARC, LGALS1, MMP7, IL1R1, CXCR2, HLA-C, CD44, LIPC, FAS, TDGF1, NCAM1, HLA-E, IL2RB, IL15, VCAM1, TIMP2, SDC1, TACR1, PTN, MRC1, FCER1G, HLA-A, L1CAM, CCR2, PTGER3, CCR9, ATP5B, GREM1, ITGB3, ITGB1, HSP90AA1, EGFR, ITGAV, CRYAB, TGFB1, ANXA1, FGA, PLAT, APOA1, LTF, TNF, PDGFA, TLR2, TLR4, CD4, WNT7A, NRP1, TLR3, CAPN5, ANXA2, PROM1, THBS1, CTSB, ITGB2, PLAU, ADA, TF, IL2RA, HLA-B, HLA-DRB1, ICAM1, CD74, HLA-DPB1, WNT1, CSF1R, ABCB1, CTSG, C1QBP, NTRK2, CXCR4, TEK, ADIPOQ, NOD2, MST1R, ADAM17, AGER, ADAM8, IL1RL1, SCARB1, MICA, CX3CL1, WNT4, KISS1R, FOLH1, MICB, SFRP4, NOTCH4, ULBP2, HLA-DRA, KLRK1, CCR7 |
cell-cell adherens junction | cellular_component | CDH1, CTNNB1, CTNNA1, CDH3, OXTR, SMAD7, NECTIN1, NECTIN3, CADM1, NECTIN4, CADM2 |
cell-cell junction | cellular_component | GJA1, PIK3R1, KIT, AKT1, CTNNB1, CTNNA1, ITGB1, ACTN4, CLDN5, CDC42, TEK, PAK1, ADAM17, NECTIN3, CADM1 |
cellular_component | cellular_component | NPTX2, CCDC22, HES5, XYLT2, PLA2G16, NUDT6 |
centriolar satellite | cellular_component | PAX2 |
centriole | cellular_component | HSPA6, AURKA, BIRC5 |
centrosome | cellular_component | GSK3B, PCNA, APEX1, CTNNB1, CCNB1, NME1, ID1, BRCA2, AURKA, SMAD7, XRCC4, PLK1, BCL2L1, NFE2L2, KIFAP3, ID2, CEP85 |
chiasma | cellular_component | MLH1 |
chloride channel complex | cellular_component | CFTR |
chromaffin granule | cellular_component | CLU |
chromatin | cellular_component | H2AFX, HMGA2, HMGA1, RB1, PLK1, HDAC2, EIF3E, PARK7, ATP1B4, NFE2L2, HDAC1, SIRT1, SUV39H2, MAF, MBD2 |
chromatin silencing complex | cellular_component | SUV39H1, SIRT1 |
chromatoid body | cellular_component | CLOCK |
chromosome | cellular_component | MSH6, H2AFX, MLH1, HMGB1, BRCA1, HMGA1, MKI67, CLOCK, SUV39H1, TERT, BIRC5, IL33, PRM1, PLK1, EHMT2, HIST3H3, HIST2H3A, SUV39H2 |
chromosome passenger complex | cellular_component | AURKA, BIRC5 |
chromosome, centromeric region | cellular_component | MKI67, SUV39H1, BIRC5, PLK1, DNMT3A, SUV39H2 |
chromosome, telomeric region | cellular_component | H2AFX, CHEK2, TERT, ATM |
chylomicron | cellular_component | APOA1, APOA2, APOE |
ciliary basal body | cellular_component | AKT1, KIFAP3 |
ciliary membrane | cellular_component | DRD2 |
ciliary neurotrophic factor receptor complex | cellular_component | IL6R, IL6ST |
ciliary tip | cellular_component | KIFAP3 |
cilium | cellular_component | AURKA, ANXA1, PROM1, ESR2 |
cis-Golgi network | cellular_component | PIK3R1 |
clathrin coat | cellular_component | IGF2R |
clathrin-coated endocytic vesicle | cellular_component | CTLA4, SFTPA1 |
clathrin-coated endocytic vesicle membrane | cellular_component | WNT5A, HLA-DRB1, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
clathrin-coated pit | cellular_component | HSPD1, SELE, TF |
clathrin-coated vesicle | cellular_component | FOLR1 |
cleavage furrow | cellular_component | ITGB1, RHOC, PLCD3, FSD1, RHOA |
coated vesicle | cellular_component | HSPD1 |
collagen trimer | cellular_component | MBL2, COL4A2, COL18A1, COL4A1, COL5A2, ADIPOQ, SFTPA1 |
collagen type IV trimer | cellular_component | COL4A2, COL4A1 |
collagen type V trimer | cellular_component | COL5A2 |
collagen type VI trimer | cellular_component | DCN |
condensed chromosome | cellular_component | MLH1, HMGB1, BRCA1, MKI67, XRCC4 |
condensed chromosome kinetochore | cellular_component | BIRC5, PLK1 |
condensed nuclear chromosome | cellular_component | H2AFX, MLH1, BRCA1, SUV39H1, KIFAP3 |
condensed nuclear chromosome outer kinetochore | cellular_component | CCNB1, PLK1 |
condensed nuclear chromosome, centromeric region | cellular_component | AURKA, PLK1 |
connexin complex | cellular_component | GJA1 |
contractile fiber | cellular_component | GJA1, CRYAB, HSPB1 |
COP9 signalosome | cellular_component | ATP5A1, HSPA6, COPS5, STOML2, NOD2 |
cornified envelope | cellular_component | ANXA1 |
cortical actin cytoskeleton | cellular_component | CDH1, CLDN5 |
cortical cytoskeleton | cellular_component | NOS2, SELE, ACTN4 |
costamere | cellular_component | KRT19, SDC4 |
CRD-mediated mRNA stability complex | cellular_component | YBX1 |
CRLF-CLCF1 complex | cellular_component | CNTF |
CSF1-CSF1R complex | cellular_component | CSF1, CSF1R |
Cul4A-RING E3 ubiquitin ligase complex | cellular_component | CDKN1B |
cyclin-dependent protein kinase activating kinase holoenzyme complex | cellular_component | HSPD1 |
cyclin-dependent protein kinase holoenzyme complex | cellular_component | CCND1, CDKN1A |
cyclin/CDK positive transcription elongation factor complex | cellular_component | RB1 |
cytoplasm | cellular_component | GSK3B, MSH6, XDH, AKR1B1, CRK, BCL2, HSPD1, PGM1, FGFR1, AKR1D1, EGR1, SRC, TXN, CDH1, YAP1, CCND1, VEGFA, STAT3, NOS2, BMP4, DNMT1, PCNA, PLA2G4A, WNT5A, MME, PTGDS, PPARG, PRDX6, CCL5, MAPK1, FGFR2, IGF2R, HMGB1, LGALS3, CLU, GJA1, CFTR, BGN, APEX1, PIK3R1, ALOX15, CHI3L1, F3, IL10, KIT, IL12B, VIM, LEP, OPRM1, MIF, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, ATF2, HPGD, CFL1, BRCA1, CCL3, NFKB1, CASP1, AR, TOB1, WNT2, AHR, CDKN1B, NOTCH1, NME1, ACE, KDR, ID1, CASP3, PLCD1, RASSF2, CCR5, FLT4, CXCR3, UCHL1, CDKN1A, HSPA6, CDKN2A, CD40, BRAF, MUC1, CTNNA1, STIP1, PDGFRA, ANXA4, ENG, BRCA2, S100P, JAK1, SPARC, TYK2, LGALS1, FLT1, KRT7, CNTF, ENO2, GSTP1, TIA1, RBP1, GSTM1, CD44, KITLG, MAP2, NAT2, CD79A, FAS, CCL2, NCAM1, HSD17B1, HOXB2, IL15, IDO1, LIF, MMP14, SELP, STMN1, STAT6, HOXA10, IL1RN, SDC1, WT1, TACR1, IL11, PTN, MDK, COMT, BMP6, LPO, CDH3, PTGS1, BDNF, CMA1, ACP1, ARNT, FLT3, IL12A, NOS3, MTOR, GSTT1, SSTR1, SRD5A2, HSPA4, SOX2, IL13, ADM, SSTR5, PTGS2, TIMP3, ZEB1, CCR2, AKR1C3, PTGFR, MKI67, AKR1C2, PSMD9 |
cytoplasmic dynein complex | cellular_component | BCL2L11 |
cytoplasmic microtubule | cellular_component | CYP2A6, SAA1, BIRC5 |
cytoplasmic ribonucleoprotein granule | cellular_component | CDC42, RAC1, ACTB |
cytoplasmic side of plasma membrane | cellular_component | CDH1, KIT, ACP1, PTEN, PTPN22 |
cytoplasmic stress granule | cellular_component | TIA1, YBX1 |
cytoplasmic vesicle | cellular_component | FGFR1, PLA2G4A, PRDX6, FOLR1, FGFR2, IGFBP2, CLU, NOTCH1, DRD2, CLCN3, KDR, FASLG, MMP14, AQP2, ITGB1, ANG, ANXA1, SOD1, APOA1, TLR2, ERBB2, PDCD6, NRP1, IL1B, IL33, ADA, SYP, RAC1, COPS5, BCL2L1, CXCR4, TLR9, GABARAPL1, ATM, GPER1, TRIM36, VEZT, OVGP1 |
cytoplasmic vesicle lumen | cellular_component | FASLG, ADA |
cytoplasmic vesicle membrane | cellular_component | AQP2, ANXA1, GABARAPL1, YWHAH, GPER1 |
cytoskeleton | cellular_component | SRC, MAPK1, VIM, CTNNB1, CCNB1, CFL1, CTNNA1, BRCA2, JAK1, TYK2, KITLG, MAP2, STMN1, NOS3, AURKA, HSPB1, BIRC5, LATS1, TPM3, TGFB1I1, NR3C1, SPRY2, KALRN, SNCG, PNP, KRT1, CDC42, PLK1, PTK2, BCL2L1, DPYSL2, ACTB, TEK, STOML2, NOD2, AIF1, FKBP4, GABARAPL1, GPER1, DAPK1, TRIM36, CEP85, Sep-09, FSD1, TMOD3, RHOA, CALD1 |
cytosol | cellular_component | GCLC, GSK3B, XDH, AKR1B1, CRK, BCL2, HSPD1, PGM1, FGFR1, AKR1D1, SRC, TXN, YAP1, CCND1, STAT3, NOS2, PLA2G4A, F2R, PPARG, PRDX6, MAPK1, CLU, GJA1, CFTR, PIK3R1, CD36, ALOX15, VIM, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, HPGD, MTHFR, CCL3, SLC6A4, NFKB1, HMGA1, CASP1, AR, AHR, CDKN1B, NOTCH1, NME1, DRD2, CASP3, PLCD1, CXCR3, UCHL1, CDKN1A, HSPA6, CDKN2A, BRAF, CTNNA1, JAK1, EDNRA, GATA2, TYK2, ENO2, GSTP1, RBP1, GSTM1, HMOX1, NAT2, FAS, HSD17B1, IDO1, STMN1, STAT6, TYMP, TACR1, PIK3CA, COMT, FLT3, NOS3, MTOR, OXTR, GSTT1, MAT2A, HSPA4, SOX2, ADM, CCR2, AKR1C3, STAR, ALDH3A2, PSMD9, GSTZ1, AURKA, INSR, CA2, HSP90AA1, JUN, FGF1, CRYAB, RHOC, MAP3K7, A2M, SOD1, PRKCB, IL1A, APOA1, S100A6, TP53, APOA2, MYC, HSPB1, BIRC5, ENO1, LATS1, FYN, TPM3, SGK1, SMAD7, WNT7A, SOCS3, MAP2K7, NRP1, FOS, ANXA2, BCL2L11, SPRY2, KALRN, PSMD10, IL1B, PNP, GPX1, ADA, KRAS, GC, CAT, GALT, CDC42, XRCC4, RAC1, ADI1, C1QBP, PTEN, PLK1, PTK2, SMAD3, RELA, BCL2L1, DICER1, EIF3E, PARK7, NTRK2, HIF1A, FOXO1, DPYSL2, BAX, PLCB1, ACTB, S100A13, HSF |
cytosolic aryl hydrocarbon receptor complex | cellular_component | AHR |
cytosolic large ribosomal subunit | cellular_component | RPL41 |
death-inducing signaling complex | cellular_component | CASP3, FAS |
dendrite | cellular_component | GSK3B, MME, OPRM1, ANXA5, DRD2, IL6ST, CRHBP, CCL2, TACR1, COMT, MTOR, CCR2, APOE, BMPR1B, NRG1, DICER1, NTRK2, DPYSL2, PAK1, GPER1, TP63, UCN, CRHR2, SEMA3A, PIAS3 |
dendrite cytoplasm | cellular_component | MAPK1, OPRM1, SOD1, ADA, GABARAPL1 |
dendrite membrane | cellular_component | OPRM1, GABARAPL1 |
dendritic shaft | cellular_component | GSK3B, CTNNB1, GPER1 |
dendritic spine | cellular_component | GSK3B, DRD2, COMT, ITGB1, PTEN, NTRK2, P2RX3 |
dendritic spine head | cellular_component | GPER1 |
dendritic spine membrane | cellular_component | GPER1, TRPV1 |
dense body | cellular_component | ACTB |
dense core granule | cellular_component | CRHBP, SOD1 |
dense core granule membrane | cellular_component | ADAM8 |
discoidal high-density lipoprotein particle | cellular_component | APOA1 |
DNA ligase IV complex | cellular_component | XRCC4 |
DNA repair complex | cellular_component | ATM |
DNA replication factor C complex | cellular_component | PCNA |
DNA-dependent protein kinase-DNA ligase 4 complex | cellular_component | XRCC4 |
dystrophin-associated glycoprotein complex | cellular_component | KRT19 |
early endosome | cellular_component | HSPD1, F2R, MAPK1, IGF2R, HMGB1, GJA1, CFTR, CLCN3, KDR, LIPC, VCAM1, ANXA1, APOA1, APOA2, APOE, CD4, NRP1, TLR3, ANXA2, PTP4A3, TF, CXCR4, F2RL1, GPER1 |
early endosome membrane | cellular_component | CFTR, CLCN3, HLA-C, HLA-E, HLA-G, HLA-A, EGFR, ANXA1, DKK1, HLA-B, RAC1 |
early phagosome | cellular_component | TLR9 |
egg coat | cellular_component | OVGP1 |
elastic fiber | cellular_component | FBLN1 |
endocytic vesicle | cellular_component | IGF2R, DRD2, CCL2, EGFR, APOA1, TF |
endocytic vesicle lumen | cellular_component | SPARC, SAA1, HSP90AA1, APOA1, APOE, HP, HPX |
endocytic vesicle membrane | cellular_component | WNT5A, CD36, HLA-DRB1, NOS3, WNT7A, HLA-DQA1, CD74, HLA-DPB1, WNT1, SCARB1, WNT4, HLA-DRA |
endolysosome lumen | cellular_component | CTSB |
endolysosome membrane | cellular_component | TLR3, TLR9 |
endomembrane system | cellular_component | SLC6A4, JAK1, MTOR, PGRMC1, PGRMC2, BCL2L11, PCSK5 |
endoplasmic reticulum | cellular_component | BCL2, PLA2G4A, PTGDS, CLU, GJA1, APEX1, CHI3L1, CYP19A1, OPRM1, ANXA5, NOTCH1, KDR, UCHL1, CYP2A6, HLA-DRB1, CRHBP, STS, HMOX1, HLA-C, HSD3B2, PLA2G2A, VCAM1, CYP2B6, PTN, PTGS1, FLT3, MTOR, HLA-A, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, ALDH3A2, CYP17A1, EGFR, PGRMC1, CYP2E1, SERPINA1, BCHE, TP53, APOE, CYP1A2, PDCD6, SGK1, FOS, TLR3, CYP26A1, PROM1, THBS1, AGR2, HLA-B, HLA-DQA1, CAT, CD74, HLA-DPB1, CYP1A1, EPHX1, PARK7, BAX, ADIPOQ, TLR9, XYLT2, SET, ATP7A, GABARAPL1, KIFAP3, GPER1, STX5, NUCB2, PLA2G16, AQP5, HSD17B7, DAD1, HSD11B2, CYP1B1, KSR1, OLFM1, HLA-DRA, SRD5A1, SGPP2, CREB3L1, PEMT |
endoplasmic reticulum exit site | cellular_component | PDCD6 |
endoplasmic reticulum lumen | cellular_component | WNT5A, COL4A2, STS, LIPC, FLT3, NTF4, PTGS2, COL18A1, SERPINA1, APOA1, BCHE, APOA2, PDGFA, CD4, WNT7A, THBS1, COL4A1, WNT1, COL5A2, GAS6, PLAUR, GHRL, WNT4, ARSH |
endoplasmic reticulum membrane | cellular_component | BCL2, PLA2G4A, PTGDS, FOLR1, GJA1, CYP19A1, NOTCH1, UCHL1, CYP2A6, HLA-DRB1, STS, HMOX1, HSD3B2, PLA2G2A, CYP2B6, PTGS1, MTOR, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, HSD17B2, ALDH3A2, CYP17A1, EGFR, PGRMC1, CYP2E1, PTGES, CD4, CYP1A2, PDCD6, SGK1, TLR3, CYP26A1, HLA-DQA1, CD74, HLA-DPB1, CYP1A1, EPHX1, CDC42, RAC1, TYRO3, BAX, PLAUR, TLR9, XYLT2, FKBP4, FKBP5, GPER1, STX5, HSD17B7, DAD1, HSD11B2, CYP1B1, NOTCH4, KSR1, SFTPA1, HLA-DRA, SRD5A1, RHOA, SGPP2, CREB3L1, PEMT |
endoplasmic reticulum Sec complex | cellular_component | CFTR |
endoplasmic reticulum-Golgi intermediate compartment | cellular_component | HMGB1, FN1, PROM1, DICER1, NUCB2 |
endoplasmic reticulum-Golgi intermediate compartment membrane | cellular_component | FOLR1, SERPINA1, STX5 |
endosome | cellular_component | CDH1, CRHR1, FOLR1, IGF2R, HMGB1, GJA1, CFTR, SLC6A4, CDKN1B, ACE, CLCN3, KDR, FPR1, CCR5, HLA-DRB1, FLT1, STS, IL15, LHCGR, MRC1, CCR2, INSR, ITGB1, EGFR, ANXA1, NGF, PDCD6, FYN, CCDC22, TLR3, ANXA2, ASTN2, PTP4A3, HLA-DQA1, CD74, HLA-DPB1, TGFB2, NTRK2, CXCR4, TLR9, GPER1, GRB14, HLA-DRA, CD1A, RHOA |
endosome lumen | cellular_component | PRLR |
endosome membrane | cellular_component | SHC1, SLC6A4, HLA-DRB1, MRC1, INSR, EGFR, ANXA1, MAP3K7, TLR4, ERBB2, TLR3, TF, HLA-DQA1, HLA-DPB1, NTRK2, TLR9, GRB14, HLA-DRA, CD1A |
endothelial microparticle | cellular_component | ANXA5, ENG |
ER to Golgi transport vesicle | cellular_component | SERPINA1 |
ER to Golgi transport vesicle membrane | cellular_component | FOLR1, HLA-DRB1, HLA-C, HLA-E, HLA-G, HLA-A, HLA-B, HLA-DQA1, CD74, HLA-DPB1, STX5, HLA-DRA |
ESC/E(Z) complex | cellular_component | HDAC2, EZH2, SIRT1 |
euchromatin | cellular_component | DNMT3A |
eukaryotic 43S preinitiation complex | cellular_component | EIF3E |
eukaryotic 48S preinitiation complex | cellular_component | EIF3E |
eukaryotic translation initiation factor 3 complex | cellular_component | COPS5, EIF3E |
excitatory synapse | cellular_component | ITGA3, FGFR2, SYP, NTRK2 |
exocytic vesicle | cellular_component | IGF1 |
external side of plasma membrane | cellular_component | ITGA6, CD40LG, ITGA3, CD36, KIT, ANXA5, ACE, CLCN3, FASLG, CCR1, CCR5, CXCR3, CD40, ENG, HLA-DRB1, IL6ST, ITGA2, CD79A, FAS, NCAM1, IL2RB, VCAM1, SELP, CTLA4, ITGB6, SDC1, FCER1G, IL13, CXCL12, ITGB1, ITGAV, IFNG, FGA, TNF, CXCL10, TLR4, CD4, THBS1, CTSB, ADA, IL2RA, ICAM1, CD74, IL4, IL6, FCER2, NRG1, IL1RL1, KLRD1, CD69, IL17A, MUC17, KLRK1, CCR7, CD83, LILRB1 |
extracellular exosome | cellular_component | AKR1B1, H2AFX, CRK, HSPD1, PGM1, ATP5A1, AKR1D1, SRC, TXN, CDH1, CETP, PCNA, WNT5A, MME, ITGA3, PTGDS, PRDX6, FBLN1, MAPK1, FOLR1, IGF2R, LGALS3, IGFBP2, CLU, GJA1, CFTR, IGFBP3, BGN, CHI3L1, F3, GPX3, DPP6, VIM, MMP9, MIF, ANXA5, CTNNB1, HPGD, EPCAM, CFL1, SERPINF1, KRT19, TNFSF10, NME1, ACE, PLCD1, FASLG, SPP1, CSF1, SDC4, UCHL1, HSPA6, CD40, MUC1, AXL, ANXA4, COL4A2, S100P, IL6ST, ITGB5, TYK2, LGALS1, KRT7, ENO2, GSTP1, MMP7, C4A, SAA1, HLA-C, CD44, AZGP1, PECAM1, FAS, NCAM1, HLA-E, PLA2G2A, LIFR, VCAM1, TIMP2, STMN1, IL1RN, ITGB6, SDC1, EFNA1, COMT, LPO, PTGS1, ACP1, PON1, CD82, HLA-A, GSTT1, HSPA4, BSG, TIMP3, COL18A1, AQP2, AKR1C3, AFM, CXCL12, RARRES1, ALDH3A2, PRELP, FN1, ATP5B, INSR, ITGB3, ITGB1, CA2, HSP90AA1, MT-CO2, ITGAV, ANG, CRYAB, ACTN4, ANXA1, RHOC, SERPINA6, A2M, PGRMC1, SOD1, FGA, SERPINA1, PLAT, PRKCB, AHSG, APOA1, TIMP1, LTF, S100A6, APOA2, APOE, C3, LGALS9, HSPB1, ENO1, PDCD6, TPM3, CLDN5, CRP, WNT7A, SLPI, LAMA5, CAPN5, CLDN3, ANXA2, PROM1, SERPINE1, THBS1, KALRN, CTSB, SNCG, IL1B, CP, |
extracellular matrix | cellular_component | MMP13, FBLN1, FGFR2, LGALS3, CLU, BGN, F3, MMP9, SERPINF1, WNT2, COL4A2, LAMA1, LGALS1, MMP7, MMP10, VCAN, MMP14, CMA1, MMP11, TNC, TIMP3, COL18A1, MMP12, PRELP, FN1, HSP90AA1, SOD1, PLAT, AHSG, TIMP1, APOE, CYR61, TGFB1I1, SLPI, LAMA5, ANXA2, SERPINE1, THBS1, KRT1, COL4A1, APCS, MMP1, CTSD, COL5A2, MMP2, MMP3, CTSG, TGFB2, RARRES2, IGFBP7, TPSAB1, LOXL1, POSTN, HTRA1, MMP24, DCN, LAMC1 |
extracellular region | cellular_component | XDH, FGFR1, TXN, CDH1, INHBA, FGF2, VEGFA, MET, CETP, BMP4, CD40LG, F2R, WNT5A, PTGDS, TNFRSF1A, MMP13, CCL5, FBLN1, FOLR1, FGFR2, HMGB1, LGALS3, IGFBP2, CLU, IGFBP3, BGN, CHI3L1, F3, GPX3, IL10, IL12B, LEP, MMP9, CXCL8, MIF, CCL3, SERPINF1, CASP1, WNT2, MBL2, TNFSF10, ERBB3, NOTCH1, ACE, KDR, FASLG, SPP1, CSF1, SDC4, FLT4, TNFRSF1B, CD40, MUC1, AGTR2, PRLR, COL4A2, FST, IGFBP5, IL6R, IL6ST, CRHBP, LAMA1, SPARC, LGALS1, HGF, FLT1, IGFBP1, CNTF, MMP7, MMP10, CXCL1, PAEP, IL1R1, C4A, CFC1B, SAA1, KITLG, LIPC, AZGP1, FAS, LEPR, CCL2, NCAM1, VCAN, PLA2G2A, IL15, LIF, LIFR, IL9, TIMP2, IL1RN, IL1R2, SDC1, CXCL2, IL11, EFNA1, PTN, MDK, BMP6, LPO, IGFBP4, BDNF, CMA1, MMP11, TNC, PTX3, PON1, IL12A, NTF4, IL13, ADM, TIMP3, VEGFC, COL18A1, MMP12, CXCL5, PTGFR, AFM, NPTX2, CXCL12, PRELP, FN1, IGF1, GREM1, HSP90AA1, EGFR, FGF1, ANG, IFNG, TGFB1, ACTN4, ANXA1, SERPINA6, A2M, SOD1, FGA, SERPINA1, PLAT, INHA, FSTL3, IL1A, AHSG, NGF, APOA1, TIMP1, LTF, BCHE, APOA2, APOE, TNF, CXCL10, PDGFA, C3, LGALS9, CCL25, TNFRSF11B, CCL2 |
extracellular space | cellular_component | XDH, AKR1B1, HSPD1, INHBA, FGF2, VEGFA, CETP, BMP4, CD40LG, WNT5A, PTGDS, TNFRSF1A, MMP13, PRDX6, CCL5, FBLN1, IGF2R, HMGB1, LGALS3, IGFBP2, CLU, IGFBP3, CD36, CHI3L1, F3, GPX3, IL10, KIT, IL12B, LEP, MMP9, CXCL8, MIF, ANXA5, CFL1, CCL3, SERPINF1, WNT2, MBL2, TNFSF10, ERBB3, ACE, FASLG, SPP1, CSF1, CD40, MUC1, AXL, ENG, IL6R, IL6ST, CRHBP, LAMA1, SPARC, LGALS1, HGF, FLT1, IGFBP1, CNTF, ENO2, GSTP1, MMP7, MMP10, CXCL1, HMOX1, IL1R1, C4A, SAA1, KITLG, LIPC, AZGP1, PECAM1, FAS, TDGF1, CCL2, VCAN, PLA2G2A, IL15, LIF, IL9, VCAM1, TIMP2, SELP, SELE, IL1RN, CXCL2, IL11, PTN, BMP6, LPO, IGFBP4, TNC, PTX3, PON1, IL12A, IL13, ADM, TIMP3, VEGFC, COL18A1, CXCL5, AFM, CXCL12, PRELP, FN1, IGF1, GREM1, CA2, EGFR, FGF1, ANG, IFNG, TGFB1, ACTN4, ANXA1, SERPINA6, A2M, SOD1, FGA, SERPINA1, PLAT, INHA, FSTL3, IL1A, AHSG, APOA1, TIMP1, LTF, BCHE, APOA2, APOE, TNF, CXCL10, PDGFA, C3, LGALS9, HSPB1, ENO1, CCL25, TNFRSF11B, CCL21, CRP, CCL22, WNT7A, NRP1, MSTN, ANGPT2, SLPI, LAMA5, DEFB4A, CCL16, ANXA2, PROM1, SERPINE1, THBS1, FIGF, |
extracellular vesicle | cellular_component | PRELP, FGA, APOA1, APOE, ITGB2 |
extrinsic component of cytoplasmic side of plasma membrane | cellular_component | SRC, ALOX15, JAK1, TYK2, S100A6, FYN, KRAS, PTK2, ERRFI1, RHOA |
extrinsic component of endoplasmic reticulum membrane | cellular_component | ALDH3A2 |
extrinsic component of endosome membrane | cellular_component | ANXA1 |
extrinsic component of external side of plasma membrane | cellular_component | ANXA1, TF |
extrinsic component of membrane | cellular_component | ANXA1, BCL2L11, PLAUR, MUC16 |
extrinsic component of plasma membrane | cellular_component | TDGF1, ENO1, ANXA2, RAC1, STOML2 |
fascia adherens | cellular_component | GJA1, CTNNB1 |
Fc-epsilon receptor I complex | cellular_component | FCER1G |
female pronucleus | cellular_component | TET3 |
fibrinogen complex | cellular_component | FBLN1, FN1, FGA, THBS1 |
filamentous actin | cellular_component | PAK1 |
filopodium | cellular_component | VCAM1, ITGB1, CDC42 |
filopodium membrane | cellular_component | ITGA3, ITGB3, ITGAV |
flotillin complex | cellular_component | CDH1, CTNNB1, CTNNA1 |
focal adhesion | cellular_component | CDH1, ITGA6, MME, ITGA3, MAPK1, IGF2R, GJA1, VIM, OPRM1, ANXA5, CTNNB1, CFL1, HMGA1, SDC4, CTNNA1, ENG, JAK1, ITGA2, ITGB5, FLT1, CD44, MMP14, SDC1, TNC, L1CAM, BSG, ITGB3, ITGB1, EGFR, ITGAV, ACTN4, ANXA1, HSPB1, NRP1, TGFB1I1, CAPN5, PAK4, PLAU, KRAS, ICAM1, CAT, CDC42, RAC1, PTK2, PLAUR, ACTB, TEK, PAK1, ADAM17, LIMK1, RND3, RHOA |
gamma-tubulin ring complex | cellular_component | BRCA1 |
gap junction | cellular_component | GJA1 |
germinal vesicle | cellular_component | AURKA |
glutamate-cysteine ligase complex | cellular_component | GCLC |
Golgi apparatus | cellular_component | MSH6, CDH1, PLA2G4A, F2R, PTGDS, PPARG, TNFRSF1A, MMP13, MAPK1, FGFR2, CLU, GJA1, CD36, OPRM1, NOTCH1, CLCN3, KDR, ID1, CTNNA1, STIP1, HLA-DRB1, CRHBP, STS, HLA-C, CD44, IL15, VCAM1, CTLA4, PTGS1, NOS3, MTOR, HLA-A, AQP2, CHEK2, ESR1, EGFR, CRYAB, LGR5, SERPINA1, FSTL3, APOE, TLR2, CXCL14, PAK4, NRAS, HLA-B, HLA-DQA1, CAT, CD74, HLA-DPB1, GALT, PAK1, F2RL1, XYLT2, ATP7A, GABARAPL1, KIFAP3, LIMK1, GPER1, STX5, PCSK5, PAX2, NUCB2, RND3, CEP85, P2RX3, CRHR2, POSTN, MANEA, PTGES2, GBGT1, CHST6, CHST2, MMP24, NPY, HLA-DRA, SMPD3 |
Golgi cis cisterna | cellular_component | SMPD3 |
Golgi lumen | cellular_component | WNT5A, BGN, SDC4, MUC1, VCAN, MMP14, SDC1, MMP11, PRELP, TGFB1, NGF, WNT7A, DEFB4A, CGA, LHB, WNT1, GAS6, PCSK5, WNT4, DEFB1, MUC16, MUC17, MUC4, DCN |
Golgi membrane | cellular_component | TNFRSF1A, FOLR1, GJA1, NOTCH1, CLCN3, HLA-DRB1, HLA-C, NCAM1, HLA-E, HLA-G, NOS3, MTOR, HLA-A, BSG, EGFR, CYP2E1, SERPINA1, PDGFA, TLR3, NRAS, HLA-B, HLA-DQA1, CD74, HLA-DPB1, CDC42, RAC1, TLR9, XYLT2, GPER1, STX5, RND3, MANEA, PTGES2, NOTCH4, GBGT1, CHST6, CHST2, HLA-DRA, SMPD3 |
Golgi-associated vesicle membrane | cellular_component | GJA1, CFTR |
granulocyte macrophage colony-stimulating factor receptor complex | cellular_component | CSF2RB |
growth cone | cellular_component | GSK3B, ITGA3, CLU, TIMP2, L1CAM, ANG, NRP1, DICER1, NTRK2, DPYSL2 |
growth cone membrane | cellular_component | NECTIN1 |
haptoglobin-hemoglobin complex | cellular_component | HP |
hemidesmosome | cellular_component | ITGA6, ITGB1 |
heterochromatin | cellular_component | DNMT1, SUV39H1, DNMT3A, CHD5, MBD2 |
HFE-transferrin receptor complex | cellular_component | BMPR1B, TF |
high-density lipoprotein particle | cellular_component | CETP, SAA1, LIPC, PON1, APOA1, APOA2, APOE |
histone acetyltransferase complex | cellular_component | KAT2B |
histone deacetylase complex | cellular_component | HDAC1, MBD2 |
histone pre-mRNA 3'end processing complex | cellular_component | YBX1 |
host cell surface | cellular_component | AXL |
I band | cellular_component | CRYAB, KAT2B |
I-kappaB/NF-kappaB complex | cellular_component | NFKB1, RELA |
IkappaB kinase complex | cellular_component | MAP3K7 |
immunological synapse | cellular_component | LGALS3, ICAM1, STOML2 |
inhibin A complex | cellular_component | INHBA, INHA |
inhibin B complex | cellular_component | INHA |
inhibin-betaglycan-ActRII complex | cellular_component | INHA |
insulin receptor complex | cellular_component | INSR |
insulin-like growth factor binding protein complex | cellular_component | IGFBP3, IGFBP5, IGF1 |
insulin-like growth factor ternary complex | cellular_component | IGFBP3, IGFBP5, IGF1 |
integral component of lumenal side of endoplasmic reticulum membrane | cellular_component | HLA-DRB1, HLA-C, HLA-E, HLA-G, HLA-A, HLA-B, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
integral component of membrane | cellular_component | BCL2, FGFR1, CDH1, ITGA6, FSHR, MET, CRHR1, CD40LG, F2R, MME, ITGA3, TNFRSF1A, FGFR2, IGF2R, GJA1, CFTR, CD36, F3, DPP6, KIT, OPRM1, EPCAM, PTGER4, SLC6A4, TNFSF10, ERBB3, NOTCH1, ACE, DRD2, CLCN3, KDR, FPR1, FASLG, CSF1, SDC4, CCR1, CCR5, FLT4, CXCR3, CSF2RB, TNFRSF1B, CD40, MUC1, PDGFRA, AXL, AGTR1, AGTR2, ENG, PRLR, HLA-DRB1, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, FLT1, STS, IL1R1, CXCR1, CXCR2, HLA-C, CD44, KITLG, CD79A, PECAM1, FAS, LEPR, NCAM1, HLA-E, KLRC1, HSD3B2, IL2RB, LIFR, VCAM1, MMP14, SELP, CTLA4, SELE, HLA-G, IL1R2, ITGB6, SDC1, TACR2, TACR1, MAOA, COMT, CDH3, LHCGR, MRC1, SLC6A2, CD82, FLT3, KIR2DL1, KIR2DL3, FCER1G, HLA-A, OXTR, SSTR1, SRD5A2, L1CAM, SSTR5, BSG, HSD17B2, AQP2, CCR2, PTGFR, PTGER3, PTGER2, KIR3DL1, KIR2DS4, RARRES1, ALDH3A2, CCR9, ESR1, INSR, ITGB3, ITGB1, EGFR, MT-CO2, ITGAV, LGR5, PGRMC1, IGF1R, TNF, PTGES, TLR2, TLR4, ERBB2, CD4, SLC22A23, BMPR1B, CLDN5, CXCR6, CLDN4, NRP1, PCDH17, PGRMC2, ABCC4, TLR3, CLDN3, PROM1, NRP2, ASTN2, TNFRSF21, NCR1, AQP8, CLDN7, ITGB2, EGF, IL2RA, HL |
integral component of nuclear inner membrane | cellular_component | P2RX3 |
integral component of plasma membrane | cellular_component | FGFR1, FSHR, MET, CRHR1, CD40LG, F2R, MME, TNFRSF1A, FOLR1, FGFR2, IGF2R, GJA1, CD36, OPRM1, EPCAM, SLC6A4, TNFSF10, ERBB3, DRD2, KDR, FASLG, SDC4, CCR1, CCR5, FLT4, CXCR3, CSF2RB, TNFRSF1B, CD40, MUC1, PDGFRA, AXL, AGTR1, AGTR2, EDNRA, FLT1, IL1R1, CXCR2, CD44, CD79A, FAS, KLRC1, IL2RB, IL15, LIFR, MMP14, SELP, CTLA4, SDC1, TACR2, TACR1, EFNA1, LHCGR, MRC1, SLC6A2, CD82, FLT3, KIR2DL1, KIR2DL3, FCER1G, HLA-A, OXTR, SSTR1, SSTR5, BSG, AQP2, CCR2, PTGFR, PTGER3, PTGER2, KIR3DL1, KIR2DS4, CCR9, INSR, ITGB3, ITGAV, LGR5, IGF1R, TNF, TLR2, TLR4, SLC22A23, BMPR1B, TNFRSF11B, CXCR6, CLDN4, TLR3, CLDN3, PROM1, TNFRSF21, NCR1, AQP8, HLA-B, HLA-DQA1, ICAM1, FCER2, CSF1R, NRG1, NTRK2, ATP1B4, TYRO3, PLAUR, TEK, F2RL1, ATP7A, NECTIN1, MST1R, ADAM17, AGER, GPER1, NECTIN3, ADAM8, CADM1, SCARB1, AMHR2, SLC26A8, TRPV1, JAG1, MICA, AQP5, P2RX3, KISS1R, FOLH1, CD69, TRO, CRHR2, IL11RA, KIR2DS5, NECTIN4, NOTCH4, CADM2, SLCO2A1, SLCO4A1, MUC4, IL1RAP, LPAR3, MMP24, HLA-DRA, CD1A, KLRK1, CCR8, CD83, KIR3DS1 |
integral component of synaptic vesicle membrane | cellular_component | SYP |
integrin alpha1-beta1 complex | cellular_component | ITGB1 |
integrin alpha10-beta1 complex | cellular_component | ITGB1 |
integrin alpha11-beta1 complex | cellular_component | ITGB1 |
integrin alpha2-beta1 complex | cellular_component | ITGA2, ITGB1 |
integrin alpha3-beta1 complex | cellular_component | ITGA3, ITGB1 |
integrin alpha7-beta1 complex | cellular_component | ITGB1 |
integrin alpha8-beta1 complex | cellular_component | ITGB1 |
integrin alpha9-beta1 complex | cellular_component | ITGB1 |
integrin alphaL-beta2 complex | cellular_component | ITGB2 |
integrin alphav-beta3 complex | cellular_component | ITGB3, ITGAV |
integrin alphav-beta5 complex | cellular_component | ITGB5, ITGAV |
integrin alphav-beta8 complex | cellular_component | ITGAV |
integrin complex | cellular_component | ITGA6, ITGA3, ITGA2, ITGB5, ITGB6, ITGB3, ITGB1, ITGAV, ITGB2 |
intercalated disc | cellular_component | GJA1, ANXA5, CTNNB1, CTNNA1, ITGB1, PAK1, YWHAH |
intercellular bridge | cellular_component | SRA1 |
intercellular canaliculus | cellular_component | MMP13 |
interleukin-12 complex | cellular_component | IL12B, IL12A |
interleukin-23 complex | cellular_component | IL12B, IL23A |
interleukin-28 receptor complex | cellular_component | IL10RB |
interleukin-6 receptor complex | cellular_component | IL6R, IL6ST, IL6 |
intermediate filament | cellular_component | GJA1, VIM, KRT19, NME1, KRT7, KRT1 |
intermediate filament cytoskeleton | cellular_component | VIM, PSMD10 |
intermediate-density lipoprotein particle | cellular_component | APOE |
interphase microtubule organizing center | cellular_component | BIRC5 |
interstitial matrix | cellular_component | TNC, IGF1, SMOC2 |
intracellular | cellular_component | BCL2, CCND1, NOS2, CD40LG, CLU, BGN, APEX1, CXCL8, ANXA5, CFL1, CCL3, ERBB3, DRD2, CXCR3, UCHL1, CSF2RB, AXL, AGTR1, PRLR, IGFBP5, CRHBP, SPARC, LGALS1, ENO2, GSTP1, CXCL1, CXCR2, IL2RB, STMN1, IL1RN, PIK3CA, OXTR, AKR1C3, HSP90AA1, EGFR, ITGAV, IFNG, ACTN4, TNF, LGALS9, HSPB1, SMAD7, CCL21, TGFB1I1, TLR3, CAPN5, CTSB, DIRAS3, PNP, PRL, GHRH, IL2RA, CSF2, CD74, IL5, CSF1R, SMAD3, BCL2L1, NTRK2, GAS6, BAX, SMAD2, CCL19, GABARAPL1, FOXP3, SMAD4, GPER1, TRIM36, TRPV1, KISS1R, ANGPT1, IL16, FSD1, CCR7, CCL11 |
intracellular membrane-bounded organelle | cellular_component | MSH6, PLA2G4A, PPARG, FGFR2, CLU, CD40, BRAF, CYP2A6, CTNNA1, COL4A2, STS, HMOX1, VCAN, CYP2B6, PTGS1, CMA1, PON1, MTOR, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, ALDH3A2, INSR, CYP17A1, CLOCK, PGRMC1, CYP2E1, IGF1R, PTGES, CYP1A2, FYN, CYP26A1, PROM1, BCL2L11, CTSB, CAT, CYP1A1, EPHX1, YBX1, HPSE, NECTIN1, DNMT3B, SCARB1, USF2, KISS1R, HSD11B2, GRB14, CYP1B1, SRD5A1 |
intracellular ribonucleoprotein complex | cellular_component | GSK3B, BRCA1, TIA1, ACTN4, TERT, YBX1, ACTB, RPL41, SRA1 |
intraciliary transport particle | cellular_component | KIFAP3 |
intrinsic component of endoplasmic reticulum membrane | cellular_component | CYP2E1 |
intrinsic component of external side of plasma membrane | cellular_component | F3 |
intrinsic component of Golgi membrane | cellular_component | CHST2 |
intrinsic component of plasma membrane | cellular_component | CRHR1, PDGFRA, TLR2, TLR4, TNFRSF21, TRPV1, ADIPOR2, ADIPOR1 |
invadopodium | cellular_component | PAK1 |
invadopodium membrane | cellular_component | ITGA3, ITGB1, PLAUR |
IPAF inflammasome complex | cellular_component | CASP1 |
keratin filament | cellular_component | KRT7, KRT1, GPER1 |
kinesin complex | cellular_component | KIFAP3 |
kinesin II complex | cellular_component | KIFAP3 |
kinetochore | cellular_component | BIRC5, PLK1, KAT2B |
lamellar body | cellular_component | SFTPA1 |
lamellipodium | cellular_component | CDH1, CTNNB1, CTNNA1, PIK3CA, ITGB1, RAC1, PTK2, AIF1, RHOA |
lamellipodium membrane | cellular_component | CFL1, ITGB3, ITGAV |
laminin-1 complex | cellular_component | LAMA1, LAMC1 |
laminin-10 complex | cellular_component | LAMA5, LAMC1 |
laminin-11 complex | cellular_component | LAMA5, LAMC1 |
laminin-2 complex | cellular_component | LAMC2 |
laminin-3 complex | cellular_component | LAMA1 |
laminin-5 complex | cellular_component | LAMA5 |
late endosome | cellular_component | SRC, F2R, MAPK1, IGF2R, GJA1, CLCN3, LIPC, TF, CD74, CXCR4, ATP7A |
late endosome membrane | cellular_component | CLCN3, HLA-DRB1, ANXA2, HLA-DRA |
lateral plasma membrane | cellular_component | CDH1, GJA1, CTNNB1, EPCAM, ERBB3, DRD2, ANXA1, CLDN4, CLDN3, CLDN7 |
leading edge membrane | cellular_component | CDC42 |
Lewy body | cellular_component | GPX1 |
lipid particle | cellular_component | ALOX15, G0S2, ANXA2 |
lipopolysaccharide receptor complex | cellular_component | HSPD1, TLR4 |
low-density lipoprotein particle | cellular_component | APOE |
lysosomal lumen | cellular_component | BGN, FASLG, SDC4, VCAN, SDC1, PRELP, HSP90AA1, GC, CD74, CTSD, PSAP, HPSE, NAGLU, DCN |
lysosomal membrane | cellular_component | IGF2R, CFTR, HLA-DRB1, MTOR, TLR3, ANXA2, CP, EGF, HLA-DQA1, CD74, HLA-DPB1, PSAP, HPSE, SCARB1, HLA-DRA |
lysosome | cellular_component | SRC, MMP13, PRDX6, IGF2R, GJA1, ACE, FASLG, HLA-DRB1, STS, MTOR, SOD1, CTSB, IL1B, ADA, HLA-DQA1, CAT, CD74, HLA-DPB1, CTSD, MPO, PSAP, HPSE, CXCR4, TLR9, PAX2, NAGLU, HLA-DRA |
M band | cellular_component | ENO1 |
macromolecular complex | cellular_component | MTOR |
macrophage migration inhibitory factor receptor complex | cellular_component | CD44, CD74 |
macropinosome | cellular_component | MMP14, ANXA2 |
male germ cell nucleus | cellular_component | H2AFX, MLH1 |
male pronucleus | cellular_component | TET3 |
MAML1-RBP-Jkappa- ICN1 complex | cellular_component | NOTCH1 |
mast cell granule | cellular_component | AKR1B1, KIT, GATA2, CXCR2, ANXA1, S100A13 |
meiotic spindle | cellular_component | AURKA |
melanosome | cellular_component | SERPINF1, MMP14, BSG, ITGB3, ITGB1, HSP90AA1, ANXA2, CTSB, CTSD, RAC1 |
membrane | cellular_component | GSK3B, MSH2, MLH1, CRK, BCL2, HSPD1, NDUFS1, ATP5A1, FGFR1, SRC, CDH1, ITGA6, YAP1, CCND1, VEGFA, FSHR, MET, CRHR1, CD40LG, F2R, MME, ITGA3, PTGDS, TNFRSF1A, PRDX6, FOLR1, FGFR2, IGF2R, HMGB1, LGALS3, CLU, GJA1, CFTR, PIK3R1, CD36, ALOX15, F3, DPP6, KIT, CYP19A1, IL12B, OPRM1, ANXA5, AKT1, CTNNB1, CCNB1, ATF2, EPCAM, CFL1, PTGER4, SLC6A4, TNFSF10, ERBB3, NOTCH1, NME1, ACE, DRD2, CLCN3, KDR, FPR1, FASLG, CSF1, SDC4, CCR1, CCR5, FLT4, CXCR3, UCHL1, CSF2RB, TNFRSF1B, CD40, BRAF, CYP2A6, MUC1, CTNNA1, PDGFRA, AXL, AGTR1, AGTR2, ENG, PRLR, HLA-DRB1, S100P, JAK1, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, TYK2, HGF, FLT1, STS, ENO2, HMOX1, IL1R1, CXCR1, CXCR2, HLA-C, CD44, KITLG, CD79A, PECAM1, FAS, LEPR, TDGF1, NCAM1, VCAN, HLA-E, KLRC1, HSD3B2, PLA2G2A, IL2RB, IL15, LIFR, VCAM1, MMP14, SELP, CTLA4, SELE, STMN1, HLA-G, IL1R2, ITGB6, SDC1, TACR2, TACR1, CYP2B6, EFNA1, PTN, MAOA, COMT, CDH3, LHCGR, MRC1, PTGS1, SLC6A2, TNC, CD82, FLT3, KIR2DL1, KIR2DL3, NOS3, MTOR, FCER1G, HLA-A, HMOX2, OXTR, SSTR1, SRD5A2, L1CAM, CYP2C19, S |
membrane attack complex | cellular_component | C5 |
membrane raft | cellular_component | GSK3B, TNFRSF1A, GJA1, CD36, OPRM1, SLC6A4, KDR, CASP3, FASLG, SDC4, TNFRSF1B, EDNRA, CD79A, PECAM1, FAS, TDGF1, SELE, STAT6, BSG, ITGB1, EGFR, TNF, TLR2, CD4, FYN, ANXA2, KRAS, ICAM1, CTSD, PARK7, HPSE, TEK, STOML2, ADAM17, P2RX3, ANGPT1, CD1A |
membrane-bounded organelle | cellular_component | GSK3B |
methionine adenosyltransferase complex | cellular_component | MAT2A |
MHC class I protein complex | cellular_component | HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, HLA-B |
MHC class Ib protein complex | cellular_component | HLA-E |
MHC class II protein complex | cellular_component | HLA-DRB1, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
microtubule | cellular_component | CRHBP, MAP2, STMN1, AURKA, BIRC5, BCL2L11, SPRY2, DPYSL2, FKBP4, GABARAPL1, Sep-09, FSD1 |
microtubule associated complex | cellular_component | MAP2 |
microtubule cytoskeleton | cellular_component | MAPK1, AKT1, AURKA, CRYAB, PLK1, KIFAP3, PMS2, SRA1 |
microtubule organizing center | cellular_component | MAPK1, CTNNB1, CCNB1, BRCA2, AURKA, LATS1, NR3C1, SNCG, CDC42, PLK1, PTK2, BCL2L1, PAX2, CEP85, FSD1 |
microvillus | cellular_component | LIPC, VCAM1, OXTR, CA2, TGFB1, PDGFA, TEK, AQP5, ANGPT1, MUC17 |
microvillus membrane | cellular_component | CTNNB1, S100P, ITGB3, ITGAV, PROM1, SCARB1 |
midbody | cellular_component | AURKA, BIRC5, ANXA2, CDC42, PLK1, RHOA |
mismatch repair complex | cellular_component | MSH2, PMS2 |
mitochondrial crista | cellular_component | STAR |
mitochondrial inner membrane | cellular_component | HSPD1, NDUFS1, ATP5A1, SRC, STAT3, PLA2G4A, LGALS3, HSD3B2, ALDH3A2, ATP5B, MT-CO2, CYP11A1, BCL2L1, STOML2, ATAD3A, CYP24A1 |
mitochondrial intermembrane space | cellular_component | NDUFS1, HSD3B2, STAR, SOD1, CAT, PARK7, STOML2 |
mitochondrial matrix | cellular_component | HSPD1, NDUFS1, ATP5A1, SHC1, BRCA1, ATP5B, CYP11A1, SOD1, TP53, NR3C1, GPX1, C1QBP, ARG2, BCL2L1, PARK7, MCL1 |
mitochondrial membrane | cellular_component | BCL2, CLU, HSD3B2, ATP5B, ANXA1, CYP11A1, BCL2L1, BAX, GPER1, ABCG2, PEMT |
mitochondrial nucleoid | cellular_component | ATP5B, TERT, ATAD3A |
mitochondrial outer membrane | cellular_component | BCL2, GJA1, ATF2, NME1, MAOA, MTOR, BCL2L11, PGR, BCL2L1, BAX, MCL1 |
mitochondrial permeability transition pore complex | cellular_component | BAX |
mitochondrial proton-transporting ATP synthase complex | cellular_component | ATP5A1, ATP5B |
mitochondrial proton-transporting ATP synthase, catalytic core | cellular_component | ATP5B |
mitochondrial respiratory chain complex I | cellular_component | NDUFS1, PARK7 |
mitochondrion | cellular_component | GSK3B, BCL2, HSPD1, NDUFS1, ATP5A1, SRC, TXN, STAT3, TNFRSF1A, MAPK1, CLU, GJA1, APEX1, AKT1, SHC1, ATF2, NFKB1, CASP1, NME1, BRAF, SPARC, GSTP1, G0S2, HSD3B2, MAOA, COMT, MTOR, BSG, STAR, ALDH3A2, XRCC3, GSTZ1, ATP5B, ESR1, CYP17A1, MT-CO2, CRYAB, CYP2E1, CYP11A1, SOD1, TP53, TERT, FYN, SGK1, NR3C1, BCL2L11, CTSB, PGR, AGR2, GPX1, KRAS, CAT, CYP1A1, MPO, PSAP, MMP2, C1QBP, PTEN, ARG2, BCL2L1, PARK7, FOXO1, DPYSL2, BAX, STOML2, FKBP4, ESR2, MCL1, GABARAPL1, SIRT1, YWHAH, GPER1, CDKN2A, TP63, ABCG2, NUDT6, CYP1B1, OLFM4, PTGES2, ATAD3A, OGG1, FHIT, CYP24A1, PEMT |
mitotic spindle | cellular_component | MAPK1, AURKA, CDC42 |
MLL5-L complex | cellular_component | ACTB |
motile cilium | cellular_component | ANXA1, HIF1A |
multivesicular body | cellular_component | GJA1, CRHBP, CD79A, CD74 |
multivesicular body, internal vesicle lumen | cellular_component | EGFR |
muscle thin filament tropomyosin | cellular_component | TPM3 |
MutLalpha complex | cellular_component | MLH1, PMS2 |
MutSalpha complex | cellular_component | MSH2, MSH6 |
MutSbeta complex | cellular_component | MSH2 |
myelin sheath | cellular_component | BCL2, NDUFS1, ATP5A1, MIF, NME1, UCHL1, STIP1, ENO2, ATP5B, CA2, HSP90AA1, CRYAB, SOD1, ENO1, ERBB2, CDC42, DPYSL2, PLCB1, SRD5A1 |
myelin sheath abaxonal region | cellular_component | ITGB1 |
myelin sheath adaxonal region | cellular_component | ANXA2, PTEN |
myofibril | cellular_component | CALD1 |
NatA complex | cellular_component | NAA15 |
nBAF complex | cellular_component | ARID1A |
neurofibrillary tangle | cellular_component | CLU |
neurofilament | cellular_component | NRP1 |
neuromuscular junction | cellular_component | F2R, PTN, ITGB1, NRG1, POSTN |
neuron projection | cellular_component | SRC, HMGB1, CLU, VIM, OPRM1, CTNNB1, MTHFR, SLC6A4, NFKB1, BRAF, MAP2, FAS, TIMP2, STMN1, SLC6A2, SSTR1, SSTR5, PTGS2, PTGER3, STAR, ESR1, HSP90AA1, ACTN4, SOD1, SGK1, FOS, SYP, CDC42, PTEN, PARK7, DPYSL2, FKBP4, ESR2, ATP7A, NECTIN1, LIMK1, TP63, P2RX3, KISS1 |
neuron projection terminus | cellular_component | MME, PTGER4, UCHL1, FSTL3, SYP |
neuronal cell body | cellular_component | GSK3B, DNMT1, DPP6, ANXA5, PTGER4, SERPINF1, UCHL1, TNFRSF1B, IL6ST, ENO2, FAS, CCL2, TIMP2, MTOR, SRD5A2, CCR2, PTGER3, STAR, IGF1, HSP90AA1, CYP17A1, ANG, TGFB1, SOD1, INHA, APOE, BMPR1B, NRP1, SNCG, ADA, CRH, CDC42, TGFB2, NTRK2, DPYSL2, FKBP4, ESR2, ATP7A, AGER, UCN, P2RX3, SST, CRHR2, KISS1, OLFM1, TBX21, SRD5A1 |
NF-kappaB complex | cellular_component | RELA |
NLRP1 inflammasome complex | cellular_component | CASP1 |
NLRP3 inflammasome complex | cellular_component | CASP1 |
nonhomologous end joining complex | cellular_component | XRCC4 |
NOS2-CD74 complex | cellular_component | CD74 |
npBAF complex | cellular_component | ARID1A |
NuA4 histone acetyltransferase complex | cellular_component | ACTB |
nuclear aryl hydrocarbon receptor complex | cellular_component | AHR, AHRR |
nuclear body | cellular_component | TP53, CDKN2A |
nuclear chromatin | cellular_component | MSH6, H2AFX, GATA3, STAT3, AR, MUC1, STAT6, ESR1, JUN, TP53, ARID1A, RUNX3, HDAC2, SMAD3, PLCB1, ACTB, SMAD2, KAT2B, HDAC1, EZH2, SIRT1, SMAD4, EHMT2, TP63, DLX5, MBD2 |
nuclear chromosome | cellular_component | MSH6, HMGA2, JUN, BIRC5 |
nuclear chromosome, telomeric region | cellular_component | MSH2, PCNA, APEX1, BRCA2, XRCC3, TERT, ATM |
nuclear envelope | cellular_component | STS, PTGS1, PTGER3, S100A6, NRM, ATP1B4, TYRO3, BAX, SIRT1, GPER1, CSE1L, NUCB2 |
nuclear envelope lumen | cellular_component | IGF2R, BCHE, PTGES |
nuclear euchromatin | cellular_component | CTNNB1, JUN, SIRT1 |
nuclear heterochromatin | cellular_component | DNMT3A, SIRT1 |
nuclear inner membrane | cellular_component | NRM, SMAD3, ATP1B4, SIRT1 |
nuclear lamina | cellular_component | SUV39H1 |
nuclear matrix | cellular_component | CFL1, SPARC, TP53, TGFB1I1, DNMT3A, OGG1 |
nuclear membrane | cellular_component | BCL2, PTGDS, PTGER4, ANXA4, EDNRA, HSD17B1, PTGER3, EGFR, PDCD6, YBX1, BCL2L1, PLCB1, PAK1, IPO13 |
nuclear nucleosome | cellular_component | HIST3H3 |
nuclear replication fork | cellular_component | PCNA |
nuclear speck | cellular_component | APEX1, WT1, HIF1A, PLCB1, OGG1, PIAS3 |
nuclear stress granule | cellular_component | TIA1 |
nuclear telomere cap complex | cellular_component | TERT |
nuclear transcription factor complex | cellular_component | CTNNB1, SOX15 |
nucleolus | cellular_component | GATA3, APEX1, HMOX1, MAP2, WT1, MKI67, FGF1, ANG, PGRMC1, TP53, TERT, MYC, SMAD7, CTSB, C1QBP, PLK1, SIRT1, CDKN2A, PAX2, CEP85, PAFAH1B2, ISG20, NANOG, IL37 |
nucleoplasm | cellular_component | MSH2, MSH6, AKR1B1, H2AFX, MLH1, EGR1, TXN, GATA3, YAP1, CCND1, BCL6, STAT3, DNMT1, PCNA, HMGA2, PPARG, MAPK1, FGFR2, HMGB1, APEX1, MIF, AKT1, CTNNB1, CCNB1, ATF2, HPGD, BRCA1, NFKB1, HMGA1, AR, AHR, CDKN1B, NOTCH1, ID1, CASP3, UCHL1, CDKN1A, VDR, XRCC1, ENG, BRCA2, GATA2, TIA1, RBP1, USF1, HSD17B1, HOXB2, IL15, SELP, STAT6, WT1, HNF1B, ARNT, MTOR, SOX2, ZEB1, CHEK2, PSMD9, XRCC3, AURKA, ESR1, HSP90AA1, JUN, FGF1, CRYAB, CLOCK, ANXA1, SOD1, PRKCB, FSTL3, TP53, SUV39H1, TERT, MYC, BIRC5, SGK1, SMAD7, NR5A2, RB1, ARID1A, FOS, NR3C1, KHDRBS3, PRDM1, PSMD10, PGR, PRM1, XRCC4, COPS5, PTEN, PLK1, YBX1, HDAC2, SMAD3, RELA, DNMT3A, EIF3E, HPSE, HIF1A, FOXP1, HES5, FOXO1, ACTB, NR5A1, HSF1, EIF4EBP1, SMAD2, HEY1, ACLY, FKBP4, ESR2, MCL1, PPARA, SET, NFKB2, POU5F1, KAT2B, HDAC1, ELAVL1, FKBP5, EZH2, SIRT1, ID2, ATM, STAT4, SMAD4, LIMK1, EHMT2, HIST3H3, STX5, DNMT3B, HIST2H3A, NR0B2, CDKN2A, CSE1L, TP63, GATA6, SUV39H2, USF2, PMS2, PLCB3, KLF9, PPRC1, NOTCH4, ISG20, NANOG, GATA5, VEZT, OGG1, CYP24A1, SRA1, MBD2, PIAS3 |
nucleosome | cellular_component | H2AFX, PRM1, HIST3H3, HIST2H3A |
nucleus | cellular_component | GSK3B, MSH2, MSH6, H2AFX, MLH1, CRK, BCL2, FGFR1, EGR1, SRC, TXN, GATA3, YAP1, FGF2, CCND1, BCL6, STAT3, NOS2, NR2F2, DNMT1, PCNA, CDX1, PLA2G4A, HMGA2, PTGDS, PPARG, MAPK1, FOLR1, FGFR2, IGF2R, HMGB1, LGALS3, CLU, IGFBP3, APEX1, PIK3R1, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, ATF2, CFL1, BRCA1, NFKB1, HMGA1, AR, TOB1, AHR, CDKN1B, NOTCH1, NME1, KDR, ID1, CASP3, RASSF2, FASLG, FLT4, CDKN1A, CDKN2A, VDR, TNFRSF1B, BRAF, XRCC1, MUC1, STIP1, PDGFRA, ANXA4, BRCA2, S100P, JAK1, ITGA2, CRHBP, GATA2, SPARC, TYK2, LGALS1, KRT7, GSTP1, TIA1, HMOX1, IL1R1, USF1, AZGP1, FAS, HOXB2, IL15, STAT6, HOXA10, WT1, HNF1B, PTGS1, ARNT, FLT3, NOS3, MTOR, HOXA11, SOX2, SSTR5, PTGS2, TIMP3, ZEB1, AKR1C3, MKI67, ALDH3A2, CHEK2, PSMD9, XRCC3, AURKA, ATP5B, ESR1, INSR, ITGB3, HSP90AA1, EGFR, JUN, FGF1, ANG, CRYAB, TGFB1, CLOCK, ACTN4, ANXA1, RHOC, MAP3K7, SOD1, PRKCB, FSTL3, APOA1, LTF, S100A6, TP53, SUV39H1, APOE, TERT, MYC, LGALS9, HSPB1, BIRC5, ENO1, ERBB2, PDCD6, FYN, SGK1, SMAD7, MEIS1, NR5A2, RB1, ARID1A, SOX15, KLF11, SNAI1, MAP2K7, |
NuRD complex | cellular_component | HDAC2, HDAC1, CHD5 |
oligosaccharyltransferase complex | cellular_component | DAD1 |
oncostatin-M receptor complex | cellular_component | IL6ST |
organelle membrane | cellular_component | CYP2A6, CYP2B6, PTGS1, MTOR, SRD5A2, CYP2C19, PTGS2, PGRMC1, CYP2E1, CYP1A2, CYP26A1, CYP1A1, EPHX1, CYP1B1, SRD5A1 |
other organism cell | cellular_component | C4BPA |
paranodal junction | cellular_component | AKR1B1 |
PCAF complex | cellular_component | KAT2B |
PCNA complex | cellular_component | PCNA |
PCNA-p21 complex | cellular_component | PCNA, CDKN1A |
PCSK9-AnxA2 complex | cellular_component | ANXA2 |
pericentric heterochromatin | cellular_component | DNMT1 |
pericentriolar material | cellular_component | CEP85 |
periciliary membrane compartment | cellular_component | KIFAP3 |
perikaryon | cellular_component | MAPK1, OPRM1, ANXA5, DRD2, CRHBP, ENO2, CCL2, CCR2, ESR1, CRH, NTRK2, AIF1, ESR2, UCN, CRHR2, OLFM1 |
perinuclear endoplasmic reticulum membrane | cellular_component | PIK3R1 |
perinuclear region of cytoplasm | cellular_component | GSK3B, AKR1B1, SRC, CDH1, INHBA, NOS2, PLA2G4A, ITGA3, PTGDS, PPARG, IGF2R, CLU, APEX1, CHI3L1, CTNNB1, SERPINF1, NME1, FASLG, SPP1, CSF1, CDKN1A, TNFRSF1B, AGTR2, ANXA4, ITGA2, HMOX1, FAS, CCL2, PLA2G2A, CTLA4, SELE, PTN, BDNF, CCR2, XRCC3, AURKA, ESR1, ITGB1, HSP90AA1, EGFR, ACTN4, S100A6, PTGES, TLR4, ERBB2, SGK1, ANXA2, CTSB, SNCG, TF, GC, COPS5, BAX, S100A13, AIF1, FKBP4, ESR2, SET, ATP7A, TNFSF13B, PTPN22, LIMK1, GPER1, PTPRR, PLA2G16, CX3CL1, LAMC2, Sep-09, OLFM4, PTGES2, SRD5A1 |
perivitelline space | cellular_component | OVGP1 |
peroxisomal matrix | cellular_component | CAT |
peroxisomal membrane | cellular_component | ALDH3A2, CAT |
peroxisome | cellular_component | XDH, NOS2, VIM, ALDH3A2, SOD1, CAT |
phagocytic cup | cellular_component | ANXA1, TNF, RAC1, AIF1 |
phagocytic vesicle | cellular_component | CD36, CLCN3, ITGB5, ITGAV, TLR9 |
phagocytic vesicle lumen | cellular_component | LTF |
phagocytic vesicle membrane | cellular_component | HLA-C, HLA-E, HLA-G, HLA-A, TLR2, HLA-B |
phagolysosome | cellular_component | ADAM8 |
phosphatidylinositol 3-kinase complex | cellular_component | PIK3R1, PIK3CA, MTOR |
phosphatidylinositol 3-kinase complex, class IA | cellular_component | PIK3R1, PIK3CA |
phosphopyruvate hydratase complex | cellular_component | ENO2, ENO1 |
photoreceptor connecting cilium | cellular_component | KIFAP3 |
photoreceptor inner segment | cellular_component | ENO2, INHA |
photoreceptor outer segment | cellular_component | PTGS1, INHA, PROM1 |
photoreceptor outer segment membrane | cellular_component | PROM1 |
plasma membrane | cellular_component | GSK3B, MSH6, CRK, ATP5A1, FGFR1, SRC, CDH1, ITGA6, FSHR, MET, STAT3, CRHR1, CD40LG, F2R, WNT5A, MME, ITGA3, TNFRSF1A, FOLR1, FGFR2, IGF2R, HMGB1, LGALS3, GJA1, CFTR, PIK3R1, CD36, ALOX15, F3, DPP6, KIT, VIM, OPRM1, ANXA5, AKT1, SHC1, CTNNB1, EPCAM, CFL1, BRCA1, PTGER4, SLC6A4, KRT19, WNT2, ERBB3, NOTCH1, ACE, DRD2, CLCN3, KDR, FPR1, CASP3, PLCD1, FASLG, CSF1, SDC4, CCR1, CCR5, FLT4, CXCR3, UCHL1, CSF2RB, TNFRSF1B, CD40, BRAF, MUC1, CTNNA1, PDGFRA, AXL, AGTR1, AGTR2, ANXA4, PRLR, HLA-DRB1, S100P, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, SPARC, FLT1, STS, ENO2, GSTP1, IL1R1, C4A, CXCR1, CXCR2, HLA-C, CD44, KITLG, CD79A, AZGP1, PECAM1, FAS, LEPR, TDGF1, NCAM1, HLA-E, KLRC1, IL2RB, LIFR, VCAM1, MMP14, SELP, CTLA4, SELE, HLA-G, IL1RN, IL1R2, ITGB6, SDC1, TACR2, TACR1, EFNA1, PIK3CA, COMT, CDH3, LHCGR, MRC1, SLC6A2, CD82, FLT3, KIR2DL1, KIR2DL3, NOS3, FCER1G, HLA-A, HMOX2, OXTR, SSTR1, L1CAM, SSTR5, BSG, AQP2, CCR2, PTGFR, PTGER3, PTGER2, KIR3DL1, KIR2DS4, CXCL12, CCR9, ATP5B, ESR1, INSR, IGF1, ITGB3, ITGB1, CA2, HSP90AA1 |
platelet alpha granule | cellular_component | SPARC, FGA, THBS1 |
platelet alpha granule lumen | cellular_component | VEGFA, CLU, SPARC, HGF, VEGFC, FN1, IGF1, TGFB1, ACTN4, A2M, FGA, SERPINA1, AHSG, TIMP1, PDGFA, SERPINE1, THBS1, FIGF, EGF, IGF2, A1BG, TGFB2, GAS6 |
platelet alpha granule membrane | cellular_component | CD36, SPARC, PECAM1, SELP, ITGB3 |
platelet dense granule lumen | cellular_component | TIMP3, RARRES2 |
platelet dense granule membrane | cellular_component | SELP, ABCC4 |
platelet dense tubular network | cellular_component | F2R |
PML body | cellular_component | MTOR, CHEK2, TP53, TERT, RB1, PTEN, EIF3E, PARK7, SIRT1, ISG20 |
podosome | cellular_component | VCAM1, ADAM8 |
polysome | cellular_component | MSI1 |
pore complex | cellular_component | BCL2, BAX |
postsynapse | cellular_component | OPRM1, AKT1, GHRL, CX3CL1 |
postsynaptic density | cellular_component | SRC, DRD2, IL1R1, FYN, NTRK2, GPER1 |
postsynaptic membrane | cellular_component | F2R, COMT, PTEN, NTRK2, NECTIN3, TRPV1 |
presynapse | cellular_component | SLC6A4, WNT7A, PARK7 |
presynaptic active zone | cellular_component | SYP, NTRK2, GPER1 |
presynaptic membrane | cellular_component | SYP, NECTIN1, GPER1 |
pronucleus | cellular_component | AURKA, HSF1, EZH2 |
proteasome complex | cellular_component | HSPB1, PSMD10 |
proteasome regulatory particle | cellular_component | PSMD9, PSMD10 |
proteasome regulatory particle, base subcomplex | cellular_component | PSMD9, PSMD10 |
protein complex | cellular_component | GSK3B, HSPD1, DNMT1, MAPK1, CLU, CFTR, AKT1, CTNNB1, BRCA1, NFKB1, AR, CDKN1B, RASSF2, STIP1, PDGFRA, BRCA2, GATA2, IL1R1, SDC1, FLT3, HOXA11, PTGS2, ESR1, HSP90AA1, ACTN4, ANXA1, SOD1, LTF, TP53, MYC, SMAD7, ANXA2, KLK3, HDAC2, SMAD3, RELA, DPYSL2, ACTB, HSF1, PAK1, EIF4EBP1, SMAD2, ADIPOQ, NOD2, FKBP4, SET, HDAC1, FOXP3, ID2, NR0B2, CDKN2A, TP63, PAX2, PLCB3, KSR1, IL1RAP, OGG1, MBD2 |
protein-DNA complex | cellular_component | HMGA2, CTNNB1, HOXA11, NFE2L2, ESR2, PAX2 |
proteinaceous extracellular matrix | cellular_component | VEGFA, BMP4, WNT5A, MMP13, FBLN1, BGN, CHI3L1, MMP9, WNT2, COL4A2, LAMA1, SPARC, LGALS1, MMP7, MMP10, VCAN, TIMP2, MMP11, TNC, TIMP3, COL18A1, MMP12, PRELP, FN1, FGF1, TGFB1, SERPINA1, TIMP1, TNFRSF11B, CYR61, WNT7A, LAMA5, ANXA2, COL4A1, MMP1, WNT1, COL5A2, MMP2, MMP3, IL1RL1, WNT4, LOXL1, LAMC2, POSTN, SFTPA1, SPOCK2, MUC4, TIMP4, SMOC2, NTN4, MMP24, DCN, LAMC1, TFF3, CRISPLD2 |
proton-transporting ATP synthase complex, catalytic core F(1) | cellular_component | ATP5A1, ATP5B |
proton-transporting two-sector ATPase complex, catalytic domain | cellular_component | ATP5A1, ATP5B |
proximal neuron projection | cellular_component | PTGER3 |
pseudopodium | cellular_component | MAPK1, ACTN4, F2RL1 |
Rad51B-Rad51C-Rad51D-XRCC2 complex | cellular_component | XRCC3 |
Rad51C-XRCC3 complex | cellular_component | XRCC3 |
Rb-E2F complex | cellular_component | RB1 |
rDNA heterochromatin | cellular_component | SUV39H1, SIRT1 |
receptor complex | cellular_component | FGFR1, ITGA3, TNFRSF1A, ERBB3, NOTCH1, FLT4, VDR, ENG, ITGB5, FLT1, LEPR, KLRC1, LIFR, ITGB6, INSR, ITGB3, ITGB1, EGFR, IGF1R, ERBB2, BMPR1B, NRP1, ITGB2, EGF, SMAD3, NTRK2, LOXL4, KLRD1, P2RX3 |
recycling endosome | cellular_component | CFTR, AQP2, ITGB1, TNF, TF, GPER1 |
replication fork | cellular_component | H2AFX, BCL6, DNMT1, XRCC3, TP53 |
replisome | cellular_component | PCNA |
respiratory chain | cellular_component | NDUFS1, MT-CO2 |
respiratory chain complex IV | cellular_component | MT-CO2 |
ribosome | cellular_component | APEX1, RPL41 |
RISC complex | cellular_component | DICER1 |
RISC-loading complex | cellular_component | DICER1 |
RNA polymerase II transcription factor complex | cellular_component | STAT3, PPARG, HMGA1, VDR, ARNT, NR5A2, HIF1A, NR5A1, SMAD4 |
RNA-directed RNA polymerase complex | cellular_component | TERT |
rough endoplasmic reticulum | cellular_component | PTGDS, CCL2, FGA, NTRK2, TP63, P2RX3, CRHR2 |
rough endoplasmic reticulum lumen | cellular_component | EDN1 |
ruffle | cellular_component | ITGB1, S100A6, ANXA2, PAK1, AIF1 |
ruffle membrane | cellular_component | SRC, CFL1, NME1, ITGB3, ITGB1, HSP90AA1, ITGAV, SPRY2, RAC1, PAK1, AIF1, ADAM17 |
sarcolemma | cellular_component | BGN, OPRM1, ANXA5, KRT19, FAS, VCAM1, BSG, ITGB1, ANXA1, ANXA2, CTSB, PLCB3, PEMT |
sarcomere | cellular_component | MMP2, TIMP4 |
sarcoplasmic reticulum | cellular_component | XDH, THBS1 |
Schmidt-Lanterman incisure | cellular_component | AKR1B1, ANXA2, PTEN |
Schwann cell microvillus | cellular_component | AKR1B1 |
Scrib-APC-beta-catenin complex | cellular_component | CTNNB1 |
secondary lysosome | cellular_component | CRHBP |
secretory granule | cellular_component | HSPD1, VEGFA, CLCN3, BRCA2, CRHBP, FAS, PLA2G2A, TGFB1, SOD1, PLAT, FSTL3, LTF, THBS1, IL1B, ITGB2, MPO, CTSG, CDC42, ATP7A, PCSK5, OLFM4 |
secretory granule lumen | cellular_component | APOA1, TF, GHRL |
semaphorin receptor complex | cellular_component | NRP1, NRP2 |
senescence-associated heterochromatin focus | cellular_component | HMGA2, HMGA1, CDKN2A |
septin complex | cellular_component | Sep-09 |
Shc-EGFR complex | cellular_component | SHC1, EGFR |
Sin3 complex | cellular_component | HDAC2, HDAC1 |
site of double-strand break | cellular_component | H2AFX, ATF2 |
SMAD protein complex | cellular_component | HMGA2, SMAD3, SMAD2, SMAD4 |
SMAD2-SMAD3 protein complex | cellular_component | SMAD3, SMAD2 |
smooth endoplasmic reticulum membrane | cellular_component | HSD3B2 |
smooth muscle contractile fiber | cellular_component | IDO1 |
SNARE complex | cellular_component | STX5 |
sodium:potassium-exchanging ATPase complex | cellular_component | ATP1B4 |
sorting endosome | cellular_component | KDR, NRP1 |
specific granule | cellular_component | CLCN3, LTF, ADAM8, OLFM4 |
sperm flagellum | cellular_component | DRD2 |
spherical high-density lipoprotein particle | cellular_component | CLU, PON1, APOA1, APOA2 |
spindle | cellular_component | MAPK1, AKT1, AURKA, HSPB1, BIRC5, RB1, NR3C1, SNCG, CDC42, PLK1, ATM |
spindle microtubule | cellular_component | AURKA, BIRC5, PLK1, KIFAP3 |
spindle midzone | cellular_component | AURKA, CDC42, PLK1 |
spindle pole | cellular_component | CTNNB1, CCNB1, AURKA, LATS1, PLK1, CEP85 |
spindle pole centrosome | cellular_component | AURKA |
spliceosomal complex | cellular_component | LGALS3 |
stereocilium bundle | cellular_component | IDO1 |
storage vacuole | cellular_component | CDC42 |
stress fiber | cellular_component | ACTN4, TPM3, PTK2, TEK, MST1R, Sep-09 |
striated muscle thin filament | cellular_component | TMOD3 |
SWI/SNF complex | cellular_component | RB1, ARID1A, NCR1 |
synapse | cellular_component | MME, ITGA3, CTNNB1, CCL2, INSR, ITGB1, SYP, COPS5, NRG1, BCL2L1, NECTIN1, GPER1, NECTIN3, CADM1, TRPV1, CADM2, OLFM1, HRH4, PIAS3 |
synaptic membrane | cellular_component | ITGA3, ITGB1 |
synaptic vesicle | cellular_component | MME, ANXA5, CLCN3, SYP, COPS5 |
synaptic vesicle membrane | cellular_component | DRD2, SYP, BCL2L1 |
synaptonemal complex | cellular_component | MLH1, PLK1 |
T cell receptor complex | cellular_component | CD4, STOML2 |
T-tubule | cellular_component | EDNRA, ESR1 |
telomerase catalytic core complex | cellular_component | TERT |
telomerase holoenzyme complex | cellular_component | TERT |
terminal bouton | cellular_component | ESR1, GHRH, SYP, NTRK2, DPYSL2, P2RX3 |
terminal web | cellular_component | KRT19 |
TERT-RMRP complex | cellular_component | TERT |
tertiary granule | cellular_component | ADAM8 |
Toll-like receptor 1-Toll-like receptor 2 protein complex | cellular_component | TLR2 |
TORC1 complex | cellular_component | MTOR |
TORC2 complex | cellular_component | MTOR |
TRAF2-GSTP1 complex | cellular_component | GSTP1 |
trans-Golgi network | cellular_component | CDH1, IGF2R, RAC1, ATP7A, GPER1, POSTN, CHST2 |
trans-Golgi network membrane | cellular_component | IGF2R, HLA-DRB1, LGR5, HLA-DQA1, CD74, HLA-DPB1, MMP24, HLA-DRA |
trans-Golgi network transport vesicle | cellular_component | IGF2R, ATP7A |
transcription factor complex | cellular_component | GATA3, YAP1, APEX1, CTNNB1, HMGA1, AHR, GATA2, USF1, HOXA10, HNF1B, ARNT, HOXA11, SOX2, ZEB1, JUN, CLOCK, SMAD7, MEIS1, RB1, FOS, SMAD3, RELA, HIF1A, SMAD2, POU5F1, SMAD4, TP63, GATA6, NAA15, GATA5 |
transcription factor TFIID complex | cellular_component | TP53 |
transcriptional repressor complex | cellular_component | CCND1, HMGB1, JUN |
transcriptionally active chromatin | cellular_component | ESR1 |
transforming growth factor beta receptor complex | cellular_component | ENG |
transport vesicle | cellular_component | IGF2R, BGN, IL33, OVGP1, CRISPLD2 |
transport vesicle membrane | cellular_component | CLCN3, HLA-DRB1, AQP2, HLA-DQA1, CD74, HLA-DPB1, HLA-DRA |
U12-type spliceosomal complex | cellular_component | YBX1 |
ubiquitin ligase complex | cellular_component | BRCA1 |
vacuole | cellular_component | CD74, MST1R |
varicosity | cellular_component | TNFRSF1B, CRHBP, CRH, UCN, CRHR2 |
very-low-density lipoprotein particle | cellular_component | APOA1, APOA2, APOE |
vesicle | cellular_component | CETP, MIF, AKT1, CFL1, MUC1, GSTP1, IL1RN, ANXA1, ANXA2, PROM1, IL1B, TF, NOD2, STX5, MUC16, MUC4, RHOA |
vesicle membrane | cellular_component | CLCN3, ANXA4 |
viral envelope | cellular_component | ERVW-1 |
virion | cellular_component | ERVW-1 |
voltage-gated potassium channel complex | cellular_component | DPP6 |
Weibel-Palade body | cellular_component | EDN1 |
Wnt signalosome | cellular_component | GSK3B, CTNNB1, WNT2 |
XY body | cellular_component | H2AFX, DNMT3A |
Z disc | cellular_component | ANXA5, CTNNB1, KRT19, CRYAB, ACTN4, HSPB1, PAK1 |
zonula adherens | cellular_component | CTNNA1 |
zymogen granule | cellular_component | PLA2G4A |
(1->3)-beta-D-glucan binding | molecular_function | PTX3 |
(R)-limonene 6-monooxygenase activity | molecular_function | CYP2C19 |
(S)-limonene 6-monooxygenase activity | molecular_function | CYP2C19 |
(S)-limonene 7-monooxygenase activity | molecular_function | CYP2C19 |
1-acyl-2-lysophosphatidylserine acylhydrolase activity | molecular_function | PLA2G16 |
1-alkyl-2-acetylglycerophosphocholine esterase activity | molecular_function | PAFAH1B2 |
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity | molecular_function | CYP24A1 |
1-phosphatidylinositol binding | molecular_function | SCARB1 |
1-phosphatidylinositol-3-kinase activity | molecular_function | FGFR1, FGF2, FGFR2, PIK3R1, PIK3CA, FGF1, TLR9, ATM, IRS2 |
1-phosphatidylinositol-3-kinase regulator activity | molecular_function | PIK3R1 |
1-phosphatidylinositol-4-phosphate 3-kinase activity | molecular_function | PIK3CA |
11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | molecular_function | HSD11B2 |
14-3-3 protein binding | molecular_function | AKT1, IRS2 |
15-hydroxyprostaglandin dehydrogenase (NAD+) activity | molecular_function | HPGD, ABCC4 |
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity | molecular_function | AKR1C3 |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity | molecular_function | HSD17B2, AKR1C1 |
17-alpha-hydroxyprogesterone aldolase activity | molecular_function | CYP17A1 |
2 iron, 2 sulfur cluster binding | molecular_function | XDH, NDUFS1 |
25-hydroxycholecalciferol-24-hydroxylase activity | molecular_function | CYP24A1 |
3'-5' exonuclease activity | molecular_function | APEX1 |
3'-5'-exoribonuclease activity | molecular_function | ISG20 |
3-beta-hydroxy-delta5-steroid dehydrogenase activity | molecular_function | HSD3B2 |
3-chloroallyl aldehyde dehydrogenase activity | molecular_function | ALDH3A2 |
3-keto sterol reductase activity | molecular_function | HSD17B7 |
3-oxo-5-alpha-steroid 4-dehydrogenase activity | molecular_function | SRD5A2, SRD5A1 |
3-phosphoinositide-dependent protein kinase binding | molecular_function | INSR, SGK1 |
4 iron, 4 sulfur cluster binding | molecular_function | NDUFS1 |
5'-deoxyribose-5-phosphate lyase activity | molecular_function | HMGA2, HMGA1 |
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity | molecular_function | OGG1 |
Ac-Asp-Glu binding | molecular_function | FOLH1 |
acetylcholinesterase activity | molecular_function | BCHE |
acetylglucosaminyltransferase activity | molecular_function | XYLT2 |
acetyltransferase activity | molecular_function | NAT2, KAT2B, NAA15 |
acid phosphatase activity | molecular_function | ACP1 |
acireductone dioxygenase [iron(II)-requiring] activity | molecular_function | ADI1 |
actin binding | molecular_function | CFL1, ACE, CCR5, ITGB1, ANG, ACTN4, TPM3, GC, PTK2, CXCR4, NOD2, AIF1, YWHAH, TAGLN, TMOD3, CALD1 |
actin filament binding | molecular_function | SLC6A4, CTNNA1, EGFR, ACTN4, AIF1 |
actin monomer binding | molecular_function | NOS3 |
actinin binding | molecular_function | NFKB1, PROM1, RELA |
activating transcription factor binding | molecular_function | PPARG, JUN, RELA, SMAD2, HDAC1 |
activin binding | molecular_function | ENG, FST, FSTL3, SMAD7 |
acyl-L-homoserine-lactone lactonohydrolase activity | molecular_function | PON1 |
acylglycerol lipase activity | molecular_function | LIPC |
adenosine deaminase activity | molecular_function | ADA |
adipokinetic hormone receptor activity | molecular_function | ADIPOR2, ADIPOR1 |
adiponectin binding | molecular_function | ADIPOR2, ADIPOR1 |
ADP binding | molecular_function | GCLC, MSH2, MSH6 |
adrenergic receptor activity | molecular_function | DRD2 |
adrenergic receptor binding | molecular_function | C1QBP |
adrenomedullin receptor binding | molecular_function | ADM |
advanced glycation end-product receptor activity | molecular_function | AGER |
aldehyde dehydrogenase (NAD) activity | molecular_function | ALDH3A2 |
aldehyde dehydrogenase [NAD(P)+] activity | molecular_function | ALDH3A2 |
alditol:NADP+ 1-oxidoreductase activity | molecular_function | AKR1B1, AKR1C3, AKR1C2, AKR1C1 |
aldo-keto reductase (NADP) activity | molecular_function | AKR1B1, AKR1D1, AKR1C3, AKR1C1 |
alpha-2A adrenergic receptor binding | molecular_function | UCHL1 |
alpha-actinin binding | molecular_function | PPARG, ITGB1 |
alpha-amylase activity | molecular_function | AMY2A |
alpha-catenin binding | molecular_function | CTNNB1 |
alpha-mannosidase activity | molecular_function | MANEA |
alpha-N-acetylglucosaminidase activity | molecular_function | NAGLU |
amide binding | molecular_function | SRD5A2, SRD5A1 |
aminoacylase activity | molecular_function | CAT |
aminopeptidase activity | molecular_function | BLMH |
anaphase-promoting complex binding | molecular_function | PTEN, PLK1 |
androgen binding | molecular_function | AR, SHBG |
androgen receptor activity | molecular_function | AR |
androgen receptor binding | molecular_function | CTNNB1, BRCA1, PRKCB, RB1, TGFB1I1, PARK7, FOXP1 |
androsterone dehydrogenase (B-specific) activity | molecular_function | AKR1C1 |
androsterone dehydrogenase activity | molecular_function | AKR1C3 |
angiotensin type I receptor activity | molecular_function | AGTR1 |
angiotensin type II receptor activity | molecular_function | AGTR1, AGTR2 |
anion transmembrane transporter activity | molecular_function | SLC26A8 |
anion:anion antiporter activity | molecular_function | SLC26A8 |
ankyrin binding | molecular_function | CDH1 |
ankyrin repeat binding | molecular_function | RELA |
annealing helicase activity | molecular_function | ANXA1 |
anti-Mullerian hormone receptor activity | molecular_function | AMHR2 |
antigen binding | molecular_function | CD40, AZGP1, HLA-G, KIR2DL3, TGFB1, MICA, MICB, ULBP2 |
antioxidant activity | molecular_function | PRDX6, SOD1, APOE, HP, CAT |
antiporter activity | molecular_function | CLCN3 |
apolipoprotein A-I binding | molecular_function | SCARB1 |
apolipoprotein A-I receptor binding | molecular_function | APOA1, CDC42 |
apolipoprotein binding | molecular_function | LIPC, SCARB1 |
apolipoprotein receptor binding | molecular_function | APOA1, APOA2 |
arachidonate 12-lipoxygenase activity | molecular_function | ALOX15 |
arachidonate 15-lipoxygenase activity | molecular_function | ALOX15, PTGS2 |
arachidonic acid binding | molecular_function | PPARG |
arachidonic acid epoxygenase activity | molecular_function | CYP2A6, CYP2B6, CYP2C19, CYP2E1 |
arginase activity | molecular_function | ARG2 |
arginine binding | molecular_function | NOS2, NOS3 |
aromatase activity | molecular_function | CYP19A1, CYP1A2, CYP1A1, CYP1B1 |
aryl hydrocarbon receptor activity | molecular_function | AHR, ARNT |
aryl hydrocarbon receptor binding | molecular_function | ARNT |
aryl sulfotransferase activity | molecular_function | SULT1E1 |
arylamine N-acetyltransferase activity | molecular_function | NAT2 |
aryldialkylphosphatase activity | molecular_function | PON1 |
arylesterase activity | molecular_function | PON1, CA2 |
arylsulfatase activity | molecular_function | ARSH |
aspartic-type endopeptidase activity | molecular_function | CASP3, CTSD |
aspartic-type endopeptidase inhibitor activity | molecular_function | WFDC2 |
AT DNA binding | molecular_function | HMGA2, HMGA1 |
ATP binding | molecular_function | GCLC, GSK3B, MSH2, MSH6, MLH1, HSPD1, ATP5A1, FGFR1, SRC, MET, MAPK1, FGFR2, CFTR, KIT, AKT1, ERBB3, NME1, CLCN3, KDR, FLT4, HSPA6, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, PIK3CA, FLT3, MTOR, MAT2A, HSPA4, MKI67, CHEK2, XRCC3, AURKA, ATP5B, INSR, HSP90AA1, EGFR, MAP3K7, IGF1R, PRKCB, TP53, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, ABCC4, KALRN, PAK4, CSF1R, ABCB1, RUNX3, PLK1, PTK2, DICER1, NTRK2, TYRO3, ACTB, TEK, PAK1, ACLY, NOD2, FKBP4, ATP7A, MST1R, ATM, NOD1, LIMK1, DAPK1, PIM2, AMHR2, ABCG2, TRPV1, PMS2, P2RX3, KSR1, CHD5, ATAD3A |
ATP citrate synthase activity | molecular_function | ACLY |
ATP-binding and phosphorylation-dependent chloride channel activity | molecular_function | CFTR |
ATP-dependent helicase activity | molecular_function | CHD5 |
ATPase activity | molecular_function | MSH2, MSH6, MLH1, HSPD1, ATP5A1, CLU, CFTR, ATP5B, HSP90AA1, ABCC4, ABCB1, ABCG2, PMS2 |
ATPase activity, coupled | molecular_function | HSPA6 |
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | molecular_function | ABCC4 |
ATPase activity, coupled to transmembrane movement of substances | molecular_function | CFTR, ABCC4, ABCB1, ABCG2 |
ATPase binding | molecular_function | AR, ESR1, PGR |
ATPase-coupled anion transmembrane transporter activity | molecular_function | CFTR, ABCC4 |
AU-rich element binding | molecular_function | TIA1, ELAVL1 |
beta-2-microglobulin binding | molecular_function | HLA-E, HLA-A, MICA, CD1A |
beta-amyloid binding | molecular_function | APOA1, BCHE, APOE, CD74, TGFB2 |
beta-catenin binding | molecular_function | GSK3B, CDH1, AR, CTNNA1, ESR1, SMAD7, FOXO1 |
beta-endorphin receptor activity | molecular_function | OPRM1 |
beta-glucuronidase activity | molecular_function | HPSE |
beta-tubulin binding | molecular_function | GJA1, GABARAPL1 |
BH domain binding | molecular_function | BAX |
BH3 domain binding | molecular_function | BCL2, BCL2L1, BAX, MCL1 |
bHLH transcription factor binding | molecular_function | USF1, PSMD9, SMAD3, SIRT1, TWIST1, USF2 |
bicarbonate transmembrane transporter activity | molecular_function | CFTR, SLC26A8 |
bile acid binding | molecular_function | AKR1C2, AKR1C1 |
binding, bridging | molecular_function | PDCD6, GAS6 |
bis(5'-adenosyl)-triphosphatase activity | molecular_function | FHIT |
BMP binding | molecular_function | ENG, GREM1 |
BMP receptor binding | molecular_function | BMP4, BMP6 |
bradykinin receptor binding | molecular_function | ACE, AGTR1 |
brain-derived neurotrophic factor binding | molecular_function | NTRK2 |
brain-derived neurotrophic factor-activated receptor activity | molecular_function | NTRK2 |
bubble DNA binding | molecular_function | HMGB1 |
C-C chemokine binding | molecular_function | CCR1, CCR5 |
C-C chemokine receptor activity | molecular_function | CCR1, CCR5, CCR2, CCR9, CCR7, CCR8 |
C-C motif chemokine 19 receptor activity | molecular_function | CCR7 |
C-C motif chemokine 21 receptor activity | molecular_function | CCR7 |
C-X-C chemokine binding | molecular_function | HMGB1, CXCR3, CXCR6 |
C-X-C chemokine receptor activity | molecular_function | CXCR3, CXCR1, CXCR2, CXCR6, CXCR4 |
C-X3-C chemokine binding | molecular_function | ITGB3, ITGB1, ITGAV |
C2H2 zinc finger domain binding | molecular_function | HMGA2, GATA2, WT1, EHMT2, MBD2 |
C5L2 anaphylatoxin chemotactic receptor binding | molecular_function | C3 |
cadherin binding | molecular_function | CTNNB1, CTNNA1, PROM1, OLFM4, MMP24 |
cadherin binding involved in cell-cell adhesion | molecular_function | EPCAM |
cadmium ion binding | molecular_function | NOS3 |
caffeine oxidase activity | molecular_function | CYP1A2 |
calcidiol binding | molecular_function | GC |
calcitriol binding | molecular_function | VDR |
calcitriol receptor activity | molecular_function | VDR |
calcium channel activity | molecular_function | TRPV1 |
calcium channel regulator activity | molecular_function | PRKCB, SGK1, NPY |
calcium ion binding | molecular_function | CDH1, PLA2G4A, MMP13, FBLN1, ANXA5, MBL2, NOTCH1, PLCD1, BRAF, ANXA4, S100P, SPARC, MMP10, VCAN, PLA2G2A, MMP14, CDH3, MMP11, PON1, MMP12, ACTN4, ANXA1, S100A6, PDCD6, CRP, PCDH17, ANXA2, THBS1, EGF, APCS, MMP1, AMY2A, MMP3, GAS6, PLCB1, S100A13, AIF1, ADAM8, JAG1, NUCB2, DLL4, PLCB3, CD69, IHH, NOTCH4, SPOCK2, SMOC2, MMP24 |
calcium-dependent cysteine-type endopeptidase activity | molecular_function | PDCD6, CAPN5 |
calcium-dependent phospholipase A2 activity | molecular_function | PLA2G4A, PLA2G2A |
calcium-dependent phospholipid binding | molecular_function | PLA2G4A, ANXA5, ANXA4, ANXA1, ANXA2 |
calcium-dependent protein binding | molecular_function | MMP13, MBL2, ANXA4, S100P, SELP, ANXA1, A2M, S100A6, PDCD6, ANXA2 |
calcium-dependent protein kinase C activity | molecular_function | CCL3, PRKCB |
calcium-dependent protein kinase regulator activity | molecular_function | HMGB1 |
calcium-release channel activity | molecular_function | TRPV1 |
calcium-transporting ATPase activity | molecular_function | ANXA5 |
calmodulin binding | molecular_function | NOS2, MAP2, NOS3, PLCB1, DAPK1, TRPV1, PLCB3, CALD1 |
calmodulin-dependent protein kinase activity | molecular_function | DAPK1 |
cAMP response element binding | molecular_function | HMGA2, ATF2, JUN, CREB3L1 |
cAMP response element binding protein binding | molecular_function | ATF2 |
cAMP-dependent protein kinase regulator activity | molecular_function | CXCL10 |
carbohydrate binding | molecular_function | LGALS3, CHI3L1, MBL2, LGALS1, VCAN, KLRC1, SELP, SELE, MRC1, BSG, NPTX2, LGALS9, KRT1, APCS, FCER2, NECTIN1, KLRD1, IL2, CD69, SFTPA1, CLEC11A, KLRK1 |
carbonate dehydratase activity | molecular_function | CA2 |
carboxylic acid binding | molecular_function | AKR1C2, AKR1C1 |
carboxylic ester hydrolase activity | molecular_function | LIPC, BCHE |
carboxypeptidase activity | molecular_function | ACE, BLMH, FOLH1, CPB2 |
CARD domain binding | molecular_function | NOD2, NOD1 |
cardiolipin binding | molecular_function | STOML2 |
catalase activity | molecular_function | CAT |
catalytic activity | molecular_function | XDH, PRDX6, HPGD, MTHFR, STS, HSD3B2, HSD17B1, GSTZ1, BCHE, PNP, AMY2A, CYP1A1, EPHX1, GALT, PAK1, ACLY, FOLH1, ILKAP, ARSH, OLFM4, OGG1, FHIT |
catechol O-methyltransferase activity | molecular_function | COMT |
cation binding | molecular_function | AMY2A, ILKAP |
cation-transporting ATPase activity | molecular_function | ATP7A |
CCR chemokine receptor binding | molecular_function | CCL21, CCL22, CCL16, CCL19, CX3CL1, CCL17, CCL11 |
CCR1 chemokine receptor binding | molecular_function | CCL5, CCL3, CCL7 |
CCR10 chemokine receptor binding | molecular_function | CCL25, CXCL13, CCL19 |
CCR2 chemokine receptor binding | molecular_function | CCL2, CCR2, CCL7 |
CCR4 chemokine receptor binding | molecular_function | CCL5 |
CCR5 chemokine receptor binding | molecular_function | STAT3, CCL5, CCL3, JAK1 |
CCR7 chemokine receptor binding | molecular_function | CCL21, CCL19 |
CD4 receptor binding | molecular_function | FYN |
CD40 receptor binding | molecular_function | CD40LG |
CD8 receptor binding | molecular_function | FYN |
cell adhesion molecule binding | molecular_function | FGFR1, SRC, CDH1, VCAM1, ITGB3, ITGB1, FGA, CLDN7, ITGB2, NECTIN1, NECTIN3, ADAM8, CADM1, POSTN, NECTIN4, CADM2 |
centromeric DNA binding | molecular_function | MSH2 |
channel activity | molecular_function | BCL2, BAX |
channel inhibitor activity | molecular_function | BCL2 |
channel-conductance-controlling ATPase activity | molecular_function | CFTR |
chaperone binding | molecular_function | HSPD1, CLU, CDKN1B, STIP1, SOD1, TP53, BIRC5, CP, BAX |
chemoattractant activity | molecular_function | FGF2, VEGFA, BMP4, CCL5, HMGB1, LGALS3, MIF, CCL3, HGF, SAA1, VEGFC, CXCL12, CCL16, FIGF |
chemoattractant activity involved in axon guidance | molecular_function | WNT5A |
chemokine (C-C motif) ligand 19 binding | molecular_function | CCR7 |
chemokine (C-C motif) ligand 21 binding | molecular_function | CCR7 |
chemokine (C-C motif) ligand 5 binding | molecular_function | CCR1, CCR5, CCR2 |
chemokine (C-C motif) ligand 7 binding | molecular_function | CCR1 |
chemokine activity | molecular_function | CCL5, CXCL8, CCL3, CXCL1, CCL2, CXCL2, CXCL5, CXCL12, CXCL10, CCL25, CCL21, CCL22, CCL16, CXCL13, CXCL14, C5, CCL19, CCL7, CX3CL1, CXCL6, CCL17, CXCL16, CCL27, CCL11 |
chemokine binding | molecular_function | CXCR3 |
chemokine receptor activity | molecular_function | CCR1, CCR5, CXCR3, CXCR1, CCR2, CCR9, CXCR6, CXCR4, CCR7, CCR8 |
chemokine receptor antagonist activity | molecular_function | CCL5 |
chemokine receptor binding | molecular_function | CCL5, CXCL12, CCL25, CCL21, CCL19, CXCL16 |
chemorepellent activity | molecular_function | APOA1, NRG1, SEMA3A, SEMA3C |
chitin binding | molecular_function | CHI3L1, OVGP1 |
chitinase activity | molecular_function | CHI3L1, OVGP1 |
chloride channel activity | molecular_function | CFTR, CLCN3, SLC26A8 |
chloride channel inhibitor activity | molecular_function | CFTR |
chloride channel regulator activity | molecular_function | CFTR, SGK1 |
chloride ion binding | molecular_function | ACE, AMY2A |
chloride transmembrane transporter activity | molecular_function | CFTR |
cholestenone 5-alpha-reductase activity | molecular_function | SRD5A2, SRD5A1 |
cholesterol binding | molecular_function | CETP, STAR, APOA1, APOA2, APOE, SYP |
cholesterol monooxygenase (side-chain-cleaving) activity | molecular_function | CYP11A1 |
cholesterol transporter activity | molecular_function | CETP, STAR, APOA1, APOA2, APOE |
choline binding | molecular_function | BCHE, CRP |
cholinesterase activity | molecular_function | BCHE |
chondroitin sulfate proteoglycan binding | molecular_function | PTN |
choriogonadotropin hormone binding | molecular_function | LHCGR |
choriogonadotropin hormone receptor activity | molecular_function | LHCGR |
chromatin binding | molecular_function | MSH6, MLH1, GATA3, YAP1, BCL6, DNMT1, PCNA, PPARG, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, NOTCH1, GATA2, ZEB1, ESR1, EGFR, JUN, PRKCB, TP53, SUV39H1, MEIS1, NR5A2, SOX15, FOS, MPO, HDAC2, SMAD3, RELA, DNMT3A, HES5, FOXO1, NR5A1, HSF1, SMAD2, NFKB2, KAT2B, EZH2, SMAD4, GPER1, DNMT3B, TP63, GATA6, GATA5, CREB3L1, MBD2 |
chromatin DNA binding | molecular_function | BCL6, STAT3, APEX1, NOTCH1, CLOCK, ACTN4, SMAD3, RELA, EZH2 |
ciliary neurotrophic factor binding | molecular_function | IL6R |
ciliary neurotrophic factor receptor activity | molecular_function | IL6R, IL6ST, LIFR |
ciliary neurotrophic factor receptor binding | molecular_function | IL6ST, CNTF, LIFR |
cis-stilbene-oxide hydrolase activity | molecular_function | EPHX1 |
co-receptor binding | molecular_function | BMP4, DKK1 |
co-SMAD binding | molecular_function | SMAD3, SMAD2 |
cobalt ion binding | molecular_function | BIRC5 |
cocaine binding | molecular_function | SLC6A4 |
coenzyme binding | molecular_function | GCLC |
cofactor binding | molecular_function | C3, BIRC5, SGK1, ACLY |
collagen binding | molecular_function | ITGA3, MMP13, MMP9, ITGA2, SPARC, CD44, FN1, ITGB1, PDGFA, SMAD7, CTSB, SMAD3, PAK1, SMAD4, DCN |
collagen binding involved in cell-matrix adhesion | molecular_function | ITGA2, ITGB1 |
collagen receptor activity | molecular_function | ITGA2 |
collagen V binding | molecular_function | THBS1 |
complement component C1q binding | molecular_function | C4A, PTX3, CRP, APCS, C1QBP |
connexin binding | molecular_function | GJA1 |
copper ion binding | molecular_function | MT-CO2, ANG, SOD1, IL1A, TP53, CP, PARK7, S100A13, ATP7A, LOXL4, LOXL1 |
copper ion transmembrane transporter activity | molecular_function | ATP7A |
copper-dependent protein binding | molecular_function | FKBP4, ATP7A |
copper-exporting ATPase activity | molecular_function | ATP7A |
core promoter binding | molecular_function | HMGA2, NOTCH1, CLOCK, RB1, HDAC2, PARK7, HDAC1, FOXP3, EZH2 |
core promoter proximal region DNA binding | molecular_function | HNF1B |
core promoter proximal region sequence-specific DNA binding | molecular_function | GATA3, SMAD3, SMAD4, PAX2 |
core promoter sequence-specific DNA binding | molecular_function | GATA3, PPARG, ESR1, CLOCK, TP53, ESR2, SIRT1, KLF10 |
coreceptor activity | molecular_function | CCR5, ITGB3, ITGB1, ITGAV, CD4, CXCR6, NRP1, CXCR4, NECTIN1, CCR8 |
corticotrophin-releasing factor receptor activity | molecular_function | CRHR1, CRHR2 |
corticotropin-releasing hormone binding | molecular_function | CRHBP |
corticotropin-releasing hormone receptor 1 binding | molecular_function | CRH, UCN |
corticotropin-releasing hormone receptor 2 binding | molecular_function | CRH, UCN, UCN2 |
corticotropin-releasing hormone receptor activity | molecular_function | CRHR2 |
coumarin 7-hydroxylase activity | molecular_function | CYP2A6 |
crossover junction endodeoxyribonuclease activity | molecular_function | XRCC3 |
CTP binding | molecular_function | HSP90AA1 |
cullin family protein binding | molecular_function | CCDC22 |
cupric ion binding | molecular_function | PARK7 |
cuprous ion binding | molecular_function | PARK7 |
CX3C chemokine receptor binding | molecular_function | CX3CL1 |
CXCR chemokine receptor binding | molecular_function | CXCL1, CXCL2, CXCL5, CXCL12, CXCL6 |
CXCR3 chemokine receptor binding | molecular_function | CXCL10, CXCL13 |
CXCR5 chemokine receptor binding | molecular_function | CXCL13 |
cyclin binding | molecular_function | CDKN1A |
cyclin-dependent protein kinase activating kinase activity | molecular_function | CDKN1A |
cyclin-dependent protein serine/threonine kinase activity | molecular_function | CCNB1 |
cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular_function | CDKN1B, CASP3, CDKN1A, CDKN2A, KAT2B |
cyclin-dependent protein serine/threonine kinase regulator activity | molecular_function | CCND1 |
cysteine-type endopeptidase activator activity involved in apoptotic process | molecular_function | CASP1, CDKN1B, CASP3, NOD1 |
cysteine-type endopeptidase activity | molecular_function | CASP1, CASP3, UCHL1, CTSB, CTSD, BLMH |
cysteine-type endopeptidase activity involved in apoptotic process | molecular_function | CASP1, CASP3 |
cysteine-type endopeptidase activity involved in execution phase of apoptosis | molecular_function | CASP3 |
cysteine-type endopeptidase inhibitor activity | molecular_function | AHSG, BIRC5, WFDC2 |
cysteine-type endopeptidase inhibitor activity involved in apoptotic process | molecular_function | BIRC5, GAS6 |
cysteine-type endopeptidase regulator activity involved in apoptotic process | molecular_function | FOXL2 |
cysteine-type peptidase activity | molecular_function | CASP1, CASP3, UCHL1, CAPN5, CTSB, BLMH |
cytochrome-c oxidase activity | molecular_function | MT-CO2 |
cytokine activity | molecular_function | INHBA, FGF2, VEGFA, BMP4, CD40LG, WNT5A, CCL5, HMGB1, IL10, IL12B, CXCL8, MIF, CCL3, WNT2, TNFSF10, FASLG, SPP1, CSF1, CNTF, CXCL1, KITLG, CCL2, IL15, LIF, IL9, IL1RN, CXCL2, IL11, BMP6, IL12A, IL13, CXCL5, CXCL12, GREM1, IFNG, TGFB1, INHA, IL1A, TIMP1, TNF, CXCL10, CCL25, TNFRSF11B, CCL21, CCL22, WNT7A, MSTN, CCL16, CXCL13, GDF9, IL1B, CXCL14, IL33, LTA, CSF2, WNT1, IL4, IL5, IL6, EDN1, TGFB2, NRG1, ADIPOQ, IL18, CCL19, TNFSF13B, IL24, IL23A, CCL7, CX3CL1, IL2, CXCL6, IL16, IL17A, IL22, IL27, CCL17, TSLP, IL17F, NODAL, GDF15, CXCL16, IL37, CCL27, CCL11 |
cytokine binding | molecular_function | KIT, LIFR, NRP1, NRP2, CD74, CSF1R, PARK7, CXCR4, IL17F |
cytokine receptor activity | molecular_function | F3, IL12B, CSF2RB, PRLR, IL6R, IL6ST, CD44, LEPR, IL2RB, LIFR, FLT3, CD74, IL1RL1, IL11RA, IL20RB, IL20RA |
cytokine receptor binding | molecular_function | IL12B, MIF, IL15, IL9, IL13, IL4, IL17A, IL17F |
cytoskeletal protein binding | molecular_function | CRYAB, ANXA2 |
damaged DNA binding | molecular_function | MSH2, MSH6, H2AFX, PCNA, HMGB1, APEX1, BRCA1, XRCC1, TP53, TP63, OGG1 |
dATP binding | molecular_function | HSP90AA1 |
deacetylase activity | molecular_function | HDAC2, HDAC1, SIRT1 |
deaminase activity | molecular_function | ADA |
death receptor binding | molecular_function | CASP3, FASLG |
delta4-3-oxosteroid 5beta-reductase activity | molecular_function | AKR1D1, AKR1C3 |
demethylase activity | molecular_function | CYP1A2, CYP1A1 |
deoxyribonuclease activity | molecular_function | NME1 |
deoxyribonuclease I activity | molecular_function | DICER1 |
dihydropyrimidinase activity | molecular_function | DPYSL2 |
dihydrosphingosine-1-phosphate phosphatase activity | molecular_function | SGPP2 |
dihydrotestosterone 17-beta-dehydrogenase activity | molecular_function | AKR1C3 |
dinitrosyl-iron complex binding | molecular_function | GSTP1 |
dinucleotide insertion or deletion binding | molecular_function | MSH2, PCNA |
dinucleotide repeat insertion binding | molecular_function | MSH2 |
dioxygenase activity | molecular_function | ALOX15, IDO1, PTGS1, PTGS2, ADI1, TET3, TET2, TET1 |
dipeptidase activity | molecular_function | FOLH1 |
dipeptidyl-peptidase activity | molecular_function | DPP6 |
disaccharide binding | molecular_function | LGALS9 |
DNA (cytosine-5-)-methyltransferase activity | molecular_function | DNMT1, DNMT3A, DNMT3B |
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates | molecular_function | DNMT1, DNMT3A, DNMT3B |
DNA binding | molecular_function | MSH2, MSH6, H2AFX, EGR1, GATA3, BCL6, STAT3, NR2F2, DNMT1, PCNA, CDX1, HMGA2, PPARG, MAPK1, HMGB1, APEX1, CTNNB1, ATF2, BRCA1, NFKB1, HMGA1, AR, AHR, VDR, BRCA2, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ZEB1, XRCC3, ESR1, JUN, ANG, CLOCK, LTF, TP53, TERT, MYC, ENO1, SMAD7, MEIS1, NR5A2, RB1, ARID1A, SOX15, KLF11, SNAI1, FOS, NR3C1, PRDM1, PGR, PRM1, XRCC4, RUNX3, YBX1, SMAD3, RELA, DNMT3A, FOXL2, HIF1A, FOXP1, HES5, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, SET, NFKB2, POU5F1, FOXP3, EZH2, ATM, STAT4, SMAD4, HIST3H3, TWIST1, DNMT3B, HIST2H3A, NR0B2, ZNF366, CDKN2A, TP63, EMX2, KLF10, GATA6, PAX2, USF2, NUCB2, PMS2, DLX5, KLF9, PTGES2, TBPL2, CHD5, NANOG, GATA5, TBX21, AHRR, OGG1, TET3, MAF, TET2, TET1, CREB3L1, MBD2 |
DNA binding, bending | molecular_function | HMGA2, HMGB1 |
DNA ligase activity | molecular_function | XRCC1 |
DNA N-glycosylase activity | molecular_function | OGG1 |
DNA polymerase binding | molecular_function | PCNA, HMGB1 |
DNA polymerase processivity factor activity | molecular_function | PCNA |
DNA replication origin binding | molecular_function | HSPD1 |
DNA-(apurinic or apyrimidinic site) lyase activity | molecular_function | HMGA2, APEX1, HMGA1, OGG1 |
DNA-dependent ATPase activity | molecular_function | XRCC3 |
DNA-dependent protein kinase activity | molecular_function | HMGA2, ATM |
DNA-methyltransferase activity | molecular_function | DNMT1, DNMT3A, DNMT3B |
dolichyl-diphosphooligosaccharide-protein glycotransferase activity | molecular_function | DAD1 |
dopachrome isomerase activity | molecular_function | MIF |
dopamine binding | molecular_function | DRD2 |
dopamine neurotransmitter receptor activity | molecular_function | DRD2 |
dopamine neurotransmitter receptor activity, coupled via Gi/Go | molecular_function | DRD2 |
dopamine:sodium symporter activity | molecular_function | SLC6A2 |
double-strand/single-strand DNA junction binding | molecular_function | MSH2 |
double-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular_function | APEX1 |
double-stranded DNA binding | molecular_function | MSH2, MSH6, DNMT1, HMGB1, CTNNB1, NFKB1, USF1, XRCC3, EGFR, JUN, TP53, NR5A2, FOS, YBX1, SMAD3, PARK7, HES5, NR5A1, SMAD2, TP63 |
double-stranded DNA exodeoxyribonuclease activity | molecular_function | APEX1 |
double-stranded DNA-dependent ATPase activity | molecular_function | ANXA1 |
double-stranded RNA binding | molecular_function | HSPD1, HMGB1, VIM, TLR3, DICER1, ELAVL1 |
double-stranded telomeric DNA binding | molecular_function | APEX1 |
drug binding | molecular_function | PPARG, FOLR1, ACE, DRD2, GSTP1, PNP, IL2RA, CXCR4, ESR2, PPARA, GPER1 |
drug transmembrane transporter activity | molecular_function | ABCG2 |
dynein binding | molecular_function | BCL2L11 |
dystroglycan binding | molecular_function | MAP2, AGR2 |
E-box binding | molecular_function | GATA3, AHR, ZEB1, CLOCK, MYC, TWIST1 |
electron carrier activity | molecular_function | XDH, AKR1B1, NDUFS1, CYP19A1, IDO1, CYP1A2, PTGES2, SRD5A1 |
endodeoxyribonuclease activity | molecular_function | APEX1 |
endogenous lipid antigen binding | molecular_function | CD1A |
endonuclease activity | molecular_function | APEX1, ANG, DICER1, PMS2, OGG1 |
endopeptidase activity | molecular_function | MME, MMP9, CASP1, ACE, CMA1, MMP12, CTSB, MMP1, KLK3, MMP3, PCSK5, PAPPA |
endopeptidase inhibitor activity | molecular_function | C4A, A2M, AHSG, C3, SLPI, SPINK1, C5, WFDC2 |
endoribonuclease activity | molecular_function | APEX1, DICER1 |
endoribonuclease activity, producing 5'-phosphomonoesters | molecular_function | DICER1 |
endothelin A receptor binding | molecular_function | EDN1 |
endothelin B receptor binding | molecular_function | EDN1 |
endothelin receptor activity | molecular_function | EDNRA |
enhancer binding | molecular_function | AHR, ARNT, SMAD3, SMAD2 |
enhancer sequence-specific DNA binding | molecular_function | GATA3, ATF2, GATA2, GATA5 |
enzyme activator activity | molecular_function | CXCL1, PSAP, DNMT3L, MMP24 |
enzyme binding | molecular_function | MSH2, H2AFX, SRC, CCND1, PCNA, PPARG, IGF2R, CFTR, AKT1, CTNNB1, BRCA1, HMGA1, AR, NOTCH1, NME1, HSPA6, CD40, XRCC1, CYP2A6, IL6R, GSTM1, HMOX1, USF1, CYP2C19, PTGS2, ESR1, ITGB3, EGFR, JUN, TGFB1, A2M, CYP2E1, SOD1, APOA1, BCHE, TP53, LGALS9, BIRC5, CD4, CYP1A2, RB1, MAP2K7, SLPI, PGR, CAT, CYP1A1, RAC1, PTEN, HDAC2, SMAD3, RELA, PARK7, HIF1A, PLAUR, PLCB1, NR5A1, NOD2, ESR2, HDAC1, MST1R, SIRT1, YWHAH, DNMT3L, PIAS3 |
enzyme inhibitor activity | molecular_function | NOTCH1, TIMP2, TIMP3, NGF, TIMP1, TIMP4 |
enzyme regulator activity | molecular_function | DNMT3L |
eoxin A4 synthase activity | molecular_function | ALOX15 |
ephrin receptor binding | molecular_function | CRK, SRC, SHC1, EFNA1, FYN |
epidermal growth factor receptor binding | molecular_function | SHC1, AGR2, EGF |
epidermal growth factor-activated receptor activity | molecular_function | EGFR |
epoxide hydrolase activity | molecular_function | EPHX1 |
ErbB-2 class receptor binding | molecular_function | NRG1, MUC4 |
ErbB-3 class receptor binding | molecular_function | PIK3R1, ERBB2, NRG1 |
estradiol 17-beta-dehydrogenase activity | molecular_function | HSD17B1, HSD17B2, HSD17B7 |
estradiol binding | molecular_function | ESR2 |
estrogen receptor activity | molecular_function | ESR1, ESR2, GPER1 |
estrogen receptor binding | molecular_function | SRC, DNMT1, PCNA, PPARG, CTNNB1, FOXL2, ZNF366, RERG |
estrogen response element binding | molecular_function | ESR1, ESR2 |
estrone sulfotransferase activity | molecular_function | SULT1E1 |
euchromatin binding | molecular_function | CTNNB1 |
eukaryotic initiation factor 4E binding | molecular_function | EIF4EBP1 |
excitatory extracellular ligand-gated ion channel activity | molecular_function | TRPV1 |
exogenous lipid antigen binding | molecular_function | CD1A |
exonuclease activity | molecular_function | APEX1, ISG20 |
exopeptidase activity | molecular_function | MME, ACE |
exoribonuclease II activity | molecular_function | ISG20 |
extracellular ATP-gated cation channel activity | molecular_function | P2RX3 |
extracellular matrix binding | molecular_function | VEGFA, BGN, SPP1, SPARC, ITGB3, ITGAV, CYR61, THBS1, SPOCK2, DCN |
extracellular matrix constituent conferring elasticity | molecular_function | COL4A1 |
extracellular matrix constituent, lubricant activity | molecular_function | MUC17, MUC4 |
extracellular matrix protein binding | molecular_function | ITGAV |
extracellular matrix structural constituent | molecular_function | FBLN1, BGN, CHI3L1, COL4A2, LAMA1, VCAN, PRELP, CD4, COL4A1, COL5A2, LAMC1 |
fatty acid binding | molecular_function | PTGDS |
ferric iron binding | molecular_function | TF |
ferric iron transmembrane transporter activity | molecular_function | TF |
ferrous iron binding | molecular_function | TF, TET2 |
ferroxidase activity | molecular_function | CP |
fibrinogen binding | molecular_function | FBLN1, THBS1 |
fibroblast growth factor binding | molecular_function | FGFR1, FGFR2, ITGB3, ITGAV, THBS1, CXCL13, S100A13 |
fibroblast growth factor receptor binding | molecular_function | FGF2, FGF1 |
fibroblast growth factor-activated receptor activity | molecular_function | FGFR1, FGFR2 |
fibronectin binding | molecular_function | VEGFA, ITGA3, MMP13, FBLN1, IGFBP3, SDC4, IGFBP5, ITGB3, ITGB1, ITGAV, FSTL3, THBS1 |
filamin binding | molecular_function | OPRM1 |
FK506 binding | molecular_function | FKBP4, FKBP5 |
flavin adenine dinucleotide binding | molecular_function | XDH, NOS2, MTHFR, MAOA, NOS3 |
flavonoid 3'-monooxygenase activity | molecular_function | CYP1A1 |
flavonol 3-sulfotransferase activity | molecular_function | SULT1E1 |
FMN binding | molecular_function | NOS2, NOS3 |
folic acid binding | molecular_function | FOLR1 |
folic acid receptor activity | molecular_function | FOLR1 |
folic acid transporter activity | molecular_function | FOLR1 |
follicle-stimulating hormone activity | molecular_function | FSHB |
follicle-stimulating hormone receptor activity | molecular_function | FSHR |
four-way junction DNA binding | molecular_function | MSH2, MSH6, HMGB1, XRCC3 |
frizzled binding | molecular_function | WNT5A, WNT2, WNT7A, WNT1, WNT4 |
frizzled-2 binding | molecular_function | WNT5A |
fucose binding | molecular_function | SELP |
G-protein alpha-subunit binding | molecular_function | F2R, IGF2R, OPRM1, F2RL1, LPAR3 |
G-protein beta-subunit binding | molecular_function | F2R, OPRM1, F2RL1 |
G-protein coupled acetylcholine receptor activity | molecular_function | HRH4 |
G-protein coupled peptide receptor activity | molecular_function | FSHR, LHCGR, KISS1R |
G-protein coupled receptor activity | molecular_function | FSHR, CRHR1, F2R, IGF2R, OPRM1, PTGER4, DRD2, FPR1, CCR1, CCR5, CXCR3, AGTR1, AGTR2, EDNRA, CXCR1, CXCR2, TACR2, TACR1, LHCGR, OXTR, SSTR1, SSTR5, CCR2, PTGFR, PTGER3, PTGER2, CCR9, LGR5, CXCR6, CXCR4, F2RL1, GPER1, KISS1R, CRHR2, SFRP4, HRH4, LPAR3, NPY, CCR7, CCR8, RXFP1 |
G-protein coupled receptor binding | molecular_function | SAA1, CCL2, FYN, PSAP, GHRL, UCN, PROK1, NPY, UCN2 |
GABA receptor binding | molecular_function | GABARAPL1 |
galactose binding | molecular_function | ENG, LGALS9 |
gamma-catenin binding | molecular_function | CDH1, CTNNA1 |
gamma-tubulin binding | molecular_function | NME1, BRCA2 |
gap junction channel activity | molecular_function | GJA1 |
gap junction channel activity involved in cardiac conduction electrical coupling | molecular_function | GJA1 |
gap junction channel activity involved in cell communication by electrical coupling | molecular_function | GJA1 |
GDP binding | molecular_function | KRAS, RERG |
geranylgeranyl reductase activity | molecular_function | AKR1C3 |
ghrelin receptor binding | molecular_function | GHRL |
globoside alpha-N-acetylgalactosaminyltransferase activity | molecular_function | GBGT1 |
glucocorticoid receptor activity | molecular_function | NR3C1 |
glucocorticoid receptor binding | molecular_function | STAT3, FLT3, FKBP4, YWHAH |
glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity | molecular_function | NR3C1 |
glutamate binding | molecular_function | GCLC |
glutamate-cysteine ligase activity | molecular_function | GCLC |
glutathione binding | molecular_function | GSTP1, GSTM1, PTGES, PTGES2 |
glutathione peroxidase activity | molecular_function | PRDX6, GPX3, GSTT1, GSTZ1, GPX1 |
glutathione transferase activity | molecular_function | GSTP1, GSTM1, GSTT1, GSTZ1 |
glyceraldehyde oxidoreductase activity | molecular_function | AKR1B1 |
glycerol channel activity | molecular_function | AQP2, AQP8, AQP5 |
glycerol transmembrane transporter activity | molecular_function | AQP2 |
glycoprotein binding | molecular_function | FGFR1, CDH1, ITGA3, IGF2R, VIM, LGALS1, AZGP1, SELP, SDC1, ITGB1, TGFB1, SERPINA1, PLAT, CD4, FYN, BMPR1B, THBS1, ITGB2 |
glycoprotein endo-alpha-1,2-mannosidase activity | molecular_function | MANEA |
glycosaminoglycan binding | molecular_function | BGN, ENG, VCAN, PTN, SPOCK2, SMOC2, DCN, CRISPLD2 |
glycosphingolipid binding | molecular_function | SELP, IL2 |
glyoxalase (glycolic acid-forming) activity | molecular_function | PARK7 |
glyoxalase III activity | molecular_function | PARK7 |
GMP binding | molecular_function | KRAS |
granulocyte macrophage colony-stimulating factor receptor binding | molecular_function | CSF2 |
growth factor activity | molecular_function | INHBA, FGF2, VEGFA, BMP4, IL10, IL12B, LEP, CSF1, HGF, CNTF, CXCL1, KITLG, TDGF1, LIF, IL9, TYMP, IL11, PTN, MDK, BMP6, BDNF, IL12A, NTF4, VEGFC, CXCL12, IGF1, FGF1, TGFB1, INHA, NGF, TIMP1, PDGFA, MSTN, FIGF, GDF9, DKK1, EGF, IGF2, AMH, CSF2, IL4, IL5, IL6, TGFB2, NRG1, JAG1, NUDT6, PROK1, IL2, NODAL, GDF15, CLEC11A |
growth factor binding | molecular_function | IGFBP2, IGFBP3, ERBB3, KDR, FLT4, IGFBP5, IL6ST, FLT1, IGFBP1, LIFR, IGFBP4, A2M, ERBB2, CYR61, NRP1, NRP2, TEK, IGFBP7, HTRA1 |
growth factor receptor binding | molecular_function | SRC, FYN |
growth hormone receptor binding | molecular_function | JAK1, TYK2 |
growth hormone-releasing hormone activity | molecular_function | GHRH, GHRL |
growth hormone-releasing hormone receptor binding | molecular_function | GHRH |
GTP binding | molecular_function | NME1, INSR, HSP90AA1, RHOC, DIRAS3, NRAS, KRAS, CDC42, RAC1, FKBP4, DAPK1, RND3, Sep-09, RHOA, RERG |
GTP-dependent protein binding | molecular_function | CDC42, RAC1 |
GTPase activating protein binding | molecular_function | CDH1, AKT1, PLCD1 |
GTPase activator activity | molecular_function | JUN, A2M, KALRN, PLCB1, ERRFI1 |
GTPase activity | molecular_function | DIRAS3, KRAS, CDC42, RAC1, RND3, Sep-09, RHOA, RERG |
GTPase binding | molecular_function | HSP90AA1, ENO1, YBX1, STOML2 |
guanine/thymine mispair binding | molecular_function | MSH2, MSH6, MLH1 |
guanyl-nucleotide exchange factor activity | molecular_function | KALRN |
H3 histone acetyltransferase activity | molecular_function | BRCA2 |
H3K27me3 modified histone binding | molecular_function | CHD5 |
H4 histone acetyltransferase activity | molecular_function | BRCA2 |
heat shock protein binding | molecular_function | NFKB1, HSPA6, HDAC2, BAX, FKBP4, FKBP5, LIMK1 |
helicase activity | molecular_function | ANXA1, DICER1, CHD5 |
heme binding | molecular_function | SRC, NOS2, CYP19A1, CYP2A6, HMOX1, IDO1, CYP2B6, LPO, PTGS1, NOS3, CYP2C19, PTGS2, CYP17A1, PGRMC1, CYP2E1, CYP11A1, CYP1A2, PGRMC2, CYP26A1, CAT, CYP1A1, MPO, CYP1B1, PTGES2, CYP24A1 |
heme oxygenase (decyclizing) activity | molecular_function | HMOX1, HMOX2 |
heme transporter activity | molecular_function | HPX, ABCG2 |
hemoglobin binding | molecular_function | HP |
heparan sulfate binding | molecular_function | PTN |
heparan sulfate proteoglycan binding | molecular_function | FST, LIPC |
heparanase activity | molecular_function | HPSE |
heparin binding | molecular_function | FGFR1, FGF2, VEGFA, BMP4, CCL5, FGFR2, MMP7, SAA1, LIPC, CCL2, SELP, PTN, MDK, PRELP, FN1, FGF1, ANG, LTF, APOE, CXCL10, CYR61, NRP1, MSTN, THBS1, CXCL13, NRP2, MPO, CTSG, CCL7, CXCL6, LAMC2, POSTN, SMOC2, CRISPLD2 |
hepatocyte growth factor-activated receptor activity | molecular_function | MET |
hepoxilin A3 synthase activity | molecular_function | ALOX15 |
hepoxilin-epoxide hydrolase activity | molecular_function | ALOX15 |
heteroduplex DNA loop binding | molecular_function | MSH2 |
high mobility group box 1 binding | molecular_function | AGER |
high-density lipoprotein particle binding | molecular_function | CD36, APOA1, APOA2, SCARB1 |
high-density lipoprotein particle receptor activity | molecular_function | SCARB1 |
high-density lipoprotein particle receptor binding | molecular_function | APOA1, APOA2 |
histamine receptor activity | molecular_function | HRH4 |
histone acetyltransferase activity | molecular_function | ATF2, BRCA2, CLOCK, KAT2B |
histone acetyltransferase binding | molecular_function | EGR1, PCNA, PLA2G4A, TP53, HIF1A, KAT2B, FOXP3 |
histone binding | molecular_function | H2AFX, PRKCB, SET, SIRT1, HIST3H3, HIST2H3A |
histone deacetylase activity | molecular_function | HDAC2, HDAC1, SIRT1 |
histone deacetylase binding | molecular_function | CCND1, DNMT1, USF1, HOXA10, HSP90AA1, PRDM1, RAC1, RELA, HIF1A, KAT2B, HDAC1, FOXP3, DNMT3B |
histone deacetylase inhibitor activity | molecular_function | UCN |
histone kinase activity | molecular_function | CCNB1 |
histone kinase activity (H3-T6 specific) | molecular_function | PRKCB |
histone methyltransferase activity | molecular_function | SUV39H1, EZH2 |
histone methyltransferase activity (H3-K27 specific) | molecular_function | EZH2, EHMT2 |
histone methyltransferase activity (H3-K9 specific) | molecular_function | SUV39H1, EHMT2, SUV39H2 |
histone serine kinase activity | molecular_function | AURKA |
histone-lysine N-methyltransferase activity | molecular_function | SUV39H1, EZH2, EHMT2, SUV39H2 |
HLA-A specific inhibitory MHC class I receptor activity | molecular_function | LILRB1 |
HLA-B specific inhibitory MHC class I receptor activity | molecular_function | KIR3DL1, LILRB1 |
HLA-C specific inhibitory MHC class I receptor activity | molecular_function | KIR2DS5 |
HLH domain binding | molecular_function | SIRT1 |
HMG box domain binding | molecular_function | GATA3, JUN, DLX5 |
hormone activity | molecular_function | INHBA, LEP, ADM, IGF1, INHA, CCL25, CGA, FSHB, LHB, PRL, GHRH, IGF2, AMH, RLN1, EDN1, CRH, ADIPOQ, GHRL, UCN, SST, HAMP, RETN, NPY, STC1, UCN2 |
hormone binding | molecular_function | ESR1, ESR2, GPER1, AMHR2, UCN2 |
hormone receptor binding | molecular_function | SRC |
Hsp70 protein binding | molecular_function | CDKN1B, STIP1, FGF1, NOD2 |
Hsp90 protein binding | molecular_function | AHR, KDR, HIF1A, NOD2 |
hyaluronic acid binding | molecular_function | CD44, VCAN, C1QBP |
hyalurononglucosaminidase activity | molecular_function | CD44 |
hydrolase activity | molecular_function | PLA2G4A, MME, MMP13, PRDX6, CFTR, APEX1, MMP9, CASP1, ACE, CASP3, PLCD1, UCHL1, STS, MMP7, MMP10, LIPC, PLA2G2A, MMP14, CMA1, MMP11, ACP1, PON1, MMP12, ATP5B, ANG, PLAT, LTF, BCHE, CAPN5, CTSB, PTP4A3, PLAU, ADA, MMP1, AMY2A, CTSD, KLK3, EPHX1, ABCB1, MMP2, MMP3, CTSG, COPS5, PTEN, ARG2, HDAC2, DICER1, PARK7, HPSE, DPYSL2, PLCB1, ATP7A, HDAC1, SIRT1, PTPN22, RARRES3, ADAM17, PCSK5, ADAM8, BLMH, TPSAB1, DUSP2, PTPRR, PLA2G16, PMS2, NUDT6, NAGLU, PLCB3, PAFAH1B2, FOLH1, PAPPA, ILKAP, IHH, ARSH, MANEA, PLCD3, CHD5, HTRA1, ISG20, CPB2, MMP24, OGG1, TPSB2, FHIT, SGPP2, SMPD3 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | molecular_function | ATP5A1, ATP5B |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular_function | CHD5 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | molecular_function | DPYSL2 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | molecular_function | KLK3 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | molecular_function | ARG2 |
hydrolase activity, acting on ester bonds | molecular_function | BCHE |
hydrolase activity, acting on glycosyl bonds | molecular_function | AMY2A, HPSE, NAGLU, OGG1 |
hydrolase activity, hydrolyzing O-glycosyl compounds | molecular_function | CHI3L1, OVGP1 |
I-SMAD binding | molecular_function | CTNNB1, SMAD7, TGFB1I1, SMAD2, SMAD4 |
ICAM-3 receptor activity | molecular_function | ITGB2 |
identical protein binding | molecular_function | BCL2, FGFR1, INHBA, VEGFA, STAT3, PCNA, PPARG, FBLN1, MAPK1, IGF2R, IL12B, VIM, MMP9, AKT1, CCL3, NFKB1, ERBB3, NME1, DRD2, BRAF, ANXA4, HGF, FAS, LEPR, NCAM1, STAT6, COL18A1, FN1, CHEK2, ESR1, ITGB3, HSP90AA1, EGFR, JUN, CRYAB, SOD1, SERPINA1, IGF1R, APOA1, BCHE, TP53, APOE, TNF, HSPB1, BIRC5, ERBB2, PDCD6, CLDN5, RB1, CLDN4, MSTN, TLR3, CLDN3, THBS1, CLDN7, CD74, SYP, CDC42, PTEN, SMAD3, RELA, BCL2L1, DNMT3A, PARK7, BAX, ACTB, ADIPOQ, SIRT1, NOD1, SMAD4, AGER, DAPK1, TP63, FHIT, ADIPOR2, ADIPOR1 |
IgE binding | molecular_function | LGALS3, FCER1G, FCER2 |
IgE receptor activity | molecular_function | FCER1G |
IgG binding | molecular_function | FCER1G |
immunoglobulin binding | molecular_function | CD4 |
indanol dehydrogenase activity | molecular_function | AKR1C3, AKR1C1 |
indoleamine 2,3-dioxygenase activity | molecular_function | IDO1 |
inhibin binding | molecular_function | INHBA, INHA |
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | molecular_function | PTEN |
insulin binding | molecular_function | PIK3R1, INSR, IGF1R |
insulin receptor binding | molecular_function | SRC, PIK3R1, SHC1, IGF1, IGF1R, IGF2, IRS2 |
insulin receptor substrate binding | molecular_function | PIK3R1, PIK3CA, INSR, IGF1R |
insulin-activated receptor activity | molecular_function | INSR |
insulin-like growth factor binding | molecular_function | IGF2R, IGFBP2, IGFBP3, IGFBP5, IGFBP1, IGFBP4, IGF1R, CYR61, IGFBP7, HTRA1 |
insulin-like growth factor I binding | molecular_function | ITGA6, IGFBP2, IGFBP3, IGFBP5, IGFBP1, IGFBP4, INSR, ITGB3, ITGAV, IGF1R |
insulin-like growth factor II binding | molecular_function | IGF2R, IGFBP2, IGFBP3, IGFBP5, IGFBP1, IGFBP4, INSR |
insulin-like growth factor receptor binding | molecular_function | PIK3R1, SHC1, INSR, IGF1, IGF2, YWHAH |
insulin-like growth factor-activated receptor activity | molecular_function | IGF2R, IGF1R |
integrin binding | molecular_function | GSK3B, SRC, ITGA6, ITGA3, FBLN1, KDR, ITGA2, VCAM1, TIMP2, MMP14, ITGB6, FN1, IGF1, ITGB1, FGF1, ACTN4, CYR61, LAMA5, THBS1, ICAM1, FCER2, NRG1, ADAM17, ADAM22, CX3CL1 |
interferon receptor activity | molecular_function | IL22RA1 |
interferon-gamma receptor binding | molecular_function | IFNG |
interleukin-1 binding | molecular_function | A2M |
interleukin-1 receptor activity | molecular_function | IL1R1, IL1R2, IL1RL1, IL1RAP |
interleukin-1 receptor antagonist activity | molecular_function | IL1RN |
interleukin-1 receptor binding | molecular_function | IL1RN, IL1A, IL1B, TLR9, IL1RAP, IL37 |
interleukin-1 Type I receptor antagonist activity | molecular_function | IL1RN |
interleukin-1 Type II receptor antagonist activity | molecular_function | IL1RN |
interleukin-1, Type I receptor binding | molecular_function | IL1RN |
interleukin-1, Type I, activating receptor activity | molecular_function | IL1R1 |
interleukin-1, Type II receptor binding | molecular_function | IL1RN |
interleukin-1, Type II, blocking receptor activity | molecular_function | IL1R2 |
interleukin-10 receptor activity | molecular_function | IL10RB |
interleukin-10 receptor binding | molecular_function | IL10 |
interleukin-11 binding | molecular_function | IL6ST |
interleukin-11 receptor activity | molecular_function | IL6ST |
interleukin-11 receptor binding | molecular_function | IL11 |
interleukin-12 alpha subunit binding | molecular_function | IL12B |
interleukin-12 beta subunit binding | molecular_function | IL12A |
interleukin-12 receptor binding | molecular_function | IL12B, IL12A |
interleukin-13 receptor binding | molecular_function | IL13 |
interleukin-2 binding | molecular_function | IL2RB, IL2RA |
interleukin-2 receptor activity | molecular_function | IL2RB, IL2RA |
interleukin-2 receptor binding | molecular_function | GATA3, IL2 |
interleukin-20 binding | molecular_function | IL22RA1, IL20RB, IL20RA |
interleukin-22 receptor binding | molecular_function | IL22 |
interleukin-23 receptor binding | molecular_function | IL12B, IL23A |
interleukin-27 binding | molecular_function | IL12A |
interleukin-27 receptor activity | molecular_function | IL6ST |
interleukin-27 receptor binding | molecular_function | IL27 |
interleukin-3 receptor activity | molecular_function | CSF2RB |
interleukin-33 binding | molecular_function | IL1RL1 |
interleukin-33 receptor activity | molecular_function | IL1RL1 |
interleukin-4 receptor binding | molecular_function | IL4 |
interleukin-5 receptor activity | molecular_function | CSF2RB |
interleukin-5 receptor binding | molecular_function | IL5 |
interleukin-6 binding | molecular_function | IL6R, IL6ST |
interleukin-6 receptor activity | molecular_function | IL6R, IL6ST |
interleukin-6 receptor binding | molecular_function | IL6R, IL6ST, CNTF, IL6, ADAM17 |
interleukin-8 binding | molecular_function | CXCR1, CXCR2, A2M |
interleukin-8 receptor activity | molecular_function | CXCR1, CXCR2 |
interleukin-8 receptor binding | molecular_function | CXCL8 |
interleukin-9 receptor binding | molecular_function | IL9 |
intermediate filament binding | molecular_function | NME1 |
intramolecular transferase activity, phosphotransferases | molecular_function | PGM1 |
intronic transcription regulatory region sequence-specific DNA binding | molecular_function | BCL6 |
ion channel activity | molecular_function | CLCN3, TRPV1, P2RX3 |
ion channel binding | molecular_function | SRC, CTNNB1, HSP90AA1, ACTN4, FYN, ID2, YWHAH |
ion transmembrane transporter activity | molecular_function | GJA1, S100A6 |
ionotropic glutamate receptor binding | molecular_function | GSK3B, CTNNB1, DRD2, IL1R1 |
iron channel inhibitor activity | molecular_function | HAMP |
iron ion binding | molecular_function | XDH, ALOX15, CYP19A1, CYP2A6, CYP2B6, NOS3, CYP2C19, CYP17A1, CYP2E1, CYP11A1, LTF, CYP1A2, CYP26A1, CYP1A1, ADI1, CYP1B1, CYP24A1, TET1 |
iron-sulfur cluster binding | molecular_function | XDH, NDUFS1 |
isomerase activity | molecular_function | PGM1, PTGDS, MIF, HSD3B2, GSTZ1, PTGES, FKBP4, FKBP5, PTGES2 |
JUN kinase binding | molecular_function | GSTP1, PTK2 |
JUN kinase kinase activity | molecular_function | MAP2K7 |
kappa-type opioid receptor binding | molecular_function | IL2 |
keratin filament binding | molecular_function | VIM, SIRT1 |
ketoreductase activity | molecular_function | AKR1C3 |
ketosteroid monooxygenase activity | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
kinase activator activity | molecular_function | IL2 |
kinase activity | molecular_function | GSK3B, FGFR1, SRC, CCND1, MET, MAPK1, FGFR2, KIT, AKT1, CCNB1, CCL3, ERBB3, NME1, KDR, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, PIK3CA, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, PLK1, PTK2, NTRK2, TYRO3, TEK, PAK1, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2 |
kinase binding | molecular_function | SRC, CTNNB1, FAS, ITGB1, RB1, SNAI1, PARK7, ERRFI1, PTPN22, KLRK1 |
kinase inhibitor activity | molecular_function | AHSG |
kinase regulator activity | molecular_function | GSTP1 |
kinesin binding | molecular_function | ACTB, KIFAP3 |
kininogen binding | molecular_function | CTSB, C1QBP |
kisspeptin receptor binding | molecular_function | KISS1 |
L-dopa decarboxylase activator activity | molecular_function | PARK7 |
lactose binding | molecular_function | LGALS1 |
lamin binding | molecular_function | PLCB1 |
laminin binding | molecular_function | ITGA3, LGALS3, ITGA2, LGALS1, ITGB1, THBS1 |
laminin-1 binding | molecular_function | NTN4 |
leptin receptor activity | molecular_function | LEPR |
leukemia inhibitory factor receptor activity | molecular_function | IL6ST, LIFR |
leukemia inhibitory factor receptor binding | molecular_function | LIF |
ligand-dependent nuclear receptor binding | molecular_function | ARID1A, SRA1 |
ligand-dependent nuclear receptor transcription coactivator activity | molecular_function | FGF2, PPARG, HMGA1, ACTN4, PRKCB, PPRC1, SRA1 |
ligase activity | molecular_function | GCLC, BRCA1, UCHL1, XRCC4, TRIM36, PIAS3 |
lipase activity | molecular_function | LIPC |
lipase inhibitor activity | molecular_function | APOA1, APOA2 |
lipid binding | molecular_function | CETP, CD36, ALOX15, AR, RBP1, LIPC, PTGS1, PTGS2, STAR, ESR1, SERPINA6, PGRMC1, APOA1, APOA2, APOE, C3, NR5A2, PGRMC2, NR3C1, PGR, SHBG, PSAP, PTEN, BAX, S100A13, NR5A1, STOML2, ESR2, PPARA, LPAR3, SULT1E1 |
lipid transporter activity | molecular_function | CETP, APOA1, APOA2, APOE, SFTPA1, SLCO2A1 |
lipoic acid binding | molecular_function | INSR |
lipopeptide binding | molecular_function | CD1A |
lipopolysaccharide binding | molecular_function | HSPD1, HMGB1, SELP, TLR2, TLR4, SCARB1 |
lipopolysaccharide receptor activity | molecular_function | TLR2, TLR4, SCARB1 |
lipoprotein particle binding | molecular_function | CD36, APOA1, APOE |
lipoteichoic acid receptor activity | molecular_function | CD36 |
lithocholic acid binding | molecular_function | VDR |
lithocholic acid receptor activity | molecular_function | VDR |
long-chain-alcohol oxidase activity | molecular_function | ALDH3A2 |
long-chain-aldehyde dehydrogenase activity | molecular_function | ALDH3A2 |
low-density lipoprotein particle binding | molecular_function | CD36, LIPC, CRP, THBS1, SCARB1 |
low-density lipoprotein particle receptor binding | molecular_function | MMP13, APOE, CRP, DKK1 |
low-density lipoprotein receptor activity | molecular_function | CD36, CXCL16 |
LRR domain binding | molecular_function | KRAS |
luteinizing hormone receptor activity | molecular_function | LHCGR |
lyase activity | molecular_function | HMGB1, APEX1, ENO2, CA2, CYP17A1, ENO1, PTGES2, OGG1 |
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | molecular_function | KAT2B |
lysophosphatidic acid receptor activity | molecular_function | LPAR3 |
lysophospholipase activity | molecular_function | PLA2G4A, LIPC |
macromolecular complex binding | molecular_function | MTOR |
macrophage colony-stimulating factor receptor activity | molecular_function | CSF1R, MST1R |
macrophage colony-stimulating factor receptor binding | molecular_function | CSF1 |
macrophage migration inhibitory factor binding | molecular_function | CD74 |
magnesium ion binding | molecular_function | GCLC, MSH2, MSH6, PGM1, NME1, S100P, ENO2, COMT, MAP3K7, ENO1, LATS1, MAP2K7, PTEN |
maleylacetoacetate isomerase activity | molecular_function | GSTZ1 |
mannose binding | molecular_function | IGF2R, MBL2, MRC1, BSG |
MAP kinase activity | molecular_function | MAPK1 |
MAP kinase kinase activity | molecular_function | MAP2K7 |
MAP kinase kinase kinase activity | molecular_function | BRAF, EGFR, MAP3K7 |
MAP kinase tyrosine/serine/threonine phosphatase activity | molecular_function | DUSP2 |
MAP-kinase scaffold activity | molecular_function | KSR1 |
MDM2/MDM4 family protein binding | molecular_function | PPARA, CDKN2A |
medium-chain-aldehyde dehydrogenase activity | molecular_function | ALDH3A2 |
mercury ion binding | molecular_function | FN1, PARK7 |
metal chelating activity | molecular_function | APOE |
metal ion binding | molecular_function | XDH, NDUFS1, PGM1, EGR1, CDH1, GATA3, ITGA6, BCL6, NOS2, NR2F2, DNMT1, PLA2G4A, MME, ITGA3, PPARG, MMP13, IGFBP3, APEX1, ALOX15, KIT, CYP19A1, MMP9, ATF2, BRCA1, SLC6A4, AR, TNFSF10, NOTCH1, NME1, ACE, PLCD1, CDKN1A, VDR, BRAF, CYP2A6, PRLR, S100P, JAK1, ITGA2, GATA2, SPARC, STS, ENO2, MMP7, MMP10, HMOX1, PLA2G2A, IDO1, TIMP2, MMP14, WT1, CYP2B6, COMT, LPO, CDH3, PTGS1, SLC6A2, MMP11, PON1, NOS3, HMOX2, MAT2A, CYP2C19, PTGS2, TIMP3, ZEB1, COL18A1, MMP12, NPTX2, CHEK2, ESR1, ITGB1, CA2, CYP17A1, MT-CO2, ITGAV, CRYAB, ACTN4, ANXA1, MAP3K7, CYP2E1, CYP11A1, SOD1, FGA, PRKCB, TIMP1, LTF, S100A6, TP53, SUV39H1, TERT, BIRC5, ENO1, CYP1A2, PDCD6, LATS1, FYN, BMPR1B, SMAD7, NR5A2, CRP, KLF11, SNAI1, MAP2K7, NRP1, TGFB1I1, ANGPT2, NR3C1, CYP26A1, KALRN, NRP2, PRDM1, PGR, CP, ITGB2, ADA, TF, APCS, HPX, MMP1, CAT, AMY2A, CYP1A1, MPO, COL5A2, FCER2, GALT, MMP2, MMP3, ADI1, COPS5, ARG2, SMAD3, DICER1, DNMT3A, FOXP1, GAS6, S100A13, NR5A1, SMAD2, ACLY, AIF1, ESR2, PPARA, ATP7A, FOXP3, SIRT1, SMAD4, ADAM17, LIMK1, EHMT2, LOX |
metallocarboxypeptidase activity | molecular_function | FOLH1, CPB2 |
metallodipeptidase activity | molecular_function | ACE |
metalloendopeptidase activity | molecular_function | MME, MMP13, MMP9, MMP7, MMP10, MMP14, MMP11, MMP12, MMP1, MMP2, MMP3, ADAM17, ADAM8, ADAM22, PAPPA, MMP24 |
metalloendopeptidase inhibitor activity | molecular_function | TIMP2, TIMP3, NGF, TIMP1, TIMP4 |
metallopeptidase activity | molecular_function | MME, MMP13, MMP9, ACE, MMP7, MMP10, MMP14, MMP11, MMP12, MMP1, MMP2, MMP3, COPS5, ADAM17, ADAM8, ADAM22, FOLH1, PAPPA, CPB2, MMP24 |
methionine adenosyltransferase activity | molecular_function | MAT2A |
methotrexate binding | molecular_function | FOLR1 |
methyl-CpG binding | molecular_function | DNMT1, MBD2 |
methylated histone binding | molecular_function | MSH6 |
methylcytosine dioxygenase activity | molecular_function | TET3, TET2, TET1 |
methylenetetrahydrofolate reductase (NAD(P)H) activity | molecular_function | MTHFR |
methyltransferase activity | molecular_function | DNMT1, COMT, SUV39H1, PRDM1, DNMT3A, EZH2, EHMT2, DNMT3B, SUV39H2, PEMT |
MH1 domain binding | molecular_function | HMGA2 |
MH2 domain binding | molecular_function | HMGA2 |
MHC class I protein binding | molecular_function | ATP5A1, HLA-E, ATP5B, KLRK1, LILRB1 |
MHC class I protein complex binding | molecular_function | KLRC1, KLRD1 |
MHC class I receptor activity | molecular_function | KIR3DS1, LILRB1 |
MHC class Ib protein binding, via antigen binding groove | molecular_function | KLRD1 |
MHC class Ib receptor activity | molecular_function | KLRK1 |
MHC class II protein binding | molecular_function | CD4, CD74 |
MHC class II protein binding, via antigen binding groove | molecular_function | CD74 |
MHC class II protein complex binding | molecular_function | HSP90AA1, HLA-DRB1, CD74, HLA-DRA |
MHC class II receptor activity | molecular_function | HLA-DRB1, HLA-DQA1, HLA-DRA |
microsatellite binding | molecular_function | HEY1 |
microtubule binding | molecular_function | MAP2, CRYAB, BIRC5, BCL2L11, PLK1, DPYSL2, OGG1 |
mineralocorticoid receptor activity | molecular_function | GPER1 |
miRNA binding | molecular_function | SOX2, POU5F1 |
misfolded protein binding | molecular_function | CLU |
mismatched DNA binding | molecular_function | MSH2, MSH6, MLH1, PMS2 |
mitochondrial ribosome binding | molecular_function | C1QBP |
mitogen-activated protein kinase binding | molecular_function | ACE, SIRT1, DUSP2 |
mitogen-activated protein kinase kinase binding | molecular_function | ACE, BRAF, KSR1 |
mitogen-activated protein kinase kinase kinase binding | molecular_function | MAPK1, MAP2K7, CDC42 |
modified amino acid binding | molecular_function | MTHFR |
molecular_function | molecular_function | G0S2, CDH3, NPTX2, TPM3, A1BG, COL5A2, NRM, AIF1, MST1, TFF3 |
molybdopterin cofactor binding | molecular_function | XDH |
monoamine transmembrane transporter activity | molecular_function | SLC6A4, SLC6A2 |
monocarboxylic acid transmembrane transporter activity | molecular_function | BSG |
monooxygenase activity | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2C19, CYP17A1, CYP2E1, CYP11A1, CYP1A2, CYP26A1, CYP1A1, CYP1B1, CYP24A1 |
monovalent inorganic cation transmembrane transporter activity | molecular_function | ATP1B4 |
morphine receptor activity | molecular_function | OPRM1 |
morphogen activity | molecular_function | GREM1, WNT1, NODAL |
mRNA 3'-UTR AU-rich region binding | molecular_function | ELAVL1 |
mRNA 3'-UTR binding | molecular_function | ELAVL1 |
mRNA binding | molecular_function | HSP90AA1, C1QBP, PARK7, ELAVL1, MBD2 |
muramyl dipeptide binding | molecular_function | NOD2 |
MutLalpha complex binding | molecular_function | MSH2, MSH6, PCNA |
MutSalpha complex binding | molecular_function | MLH1, PMS2 |
myosin binding | molecular_function | SLC6A4, VEZT, RHOA, CALD1 |
myosin light chain binding | molecular_function | CXCR4 |
N-acetylglucosamine 6-O-sulfotransferase activity | molecular_function | CHST6, CHST2 |
N-acetyltransferase activity | molecular_function | KAT2B |
N-formyl peptide receptor activity | molecular_function | FPR1 |
N-methyltransferase activity | molecular_function | PEMT |
NAD binding | molecular_function | HPGD, HSD11B2 |
NAD+ ADP-ribosyltransferase activity | molecular_function | SIRT1 |
NAD+ binding | molecular_function | HPGD, SIRT1 |
NAD-dependent histone deacetylase activity | molecular_function | SIRT1 |
NAD-dependent histone deacetylase activity (H3-K14 specific) | molecular_function | HDAC2, HDAC1 |
NAD-dependent histone deacetylase activity (H3-K9 specific) | molecular_function | SIRT1 |
NAD-dependent protein deacetylase activity | molecular_function | SIRT1 |
NADH dehydrogenase (ubiquinone) activity | molecular_function | NDUFS1 |
NADH dehydrogenase activity | molecular_function | NDUFS1 |
NADP binding | molecular_function | NOS2, MTHFR, NOS3, CAT |
NADP-retinol dehydrogenase activity | molecular_function | AKR1C3 |
NADPH binding | molecular_function | SRD5A1 |
natural killer cell lectin-like receptor binding | molecular_function | HLA-E, MICA, MICB, ULBP2 |
nerve growth factor receptor binding | molecular_function | NGF |
neuregulin binding | molecular_function | ITGA6, ERBB3, ITGB3, ITGAV |
neuropeptide binding | molecular_function | OPRM1, SSTR1, SSTR5, KISS1R |
neuropeptide hormone activity | molecular_function | CRH, UCN, NPY |
neuropeptide receptor activity | molecular_function | KISS1R |
neuropilin binding | molecular_function | VEGFA, SEMA3A, SEMA3C |
neurotransmitter:sodium symporter activity | molecular_function | SLC6A4, SLC6A2 |
neurotrophin binding | molecular_function | NTRK2 |
neurotrophin p75 receptor binding | molecular_function | NTF4 |
neurotrophin receptor activity | molecular_function | NTRK2 |
neurotrophin TRKA receptor binding | molecular_function | PIK3R1, SHC1 |
neurotrophin TRKB receptor binding | molecular_function | BDNF |
NF-kappaB binding | molecular_function | GSK3B, APEX1, CDKN2A, ANXA4, HDAC2, RELA, HDAC1, FOXP3 |
NFAT protein binding | molecular_function | PPARA, FOXP3 |
nitric oxide binding | molecular_function | GSTP1 |
nitric-oxide synthase activity | molecular_function | NOS2, NOS3 |
nitric-oxide synthase binding | molecular_function | CTNNB1, SLC6A4, CD74, ACTB |
nitric-oxide synthase regulator activity | molecular_function | AKT1, ESR1, HSP90AA1, EGFR |
non-membrane spanning protein tyrosine kinase activity | molecular_function | SRC, JAK1, TYK2, FYN, PTK2 |
non-membrane spanning protein tyrosine phosphatase activity | molecular_function | ACP1 |
norepinephrine:sodium symporter activity | molecular_function | SLC6A2 |
Notch binding | molecular_function | NOTCH1, ADAM17, JAG1, DLL4 |
nuclear export signal receptor activity | molecular_function | CSE1L |
nuclear hormone receptor binding | molecular_function | CTNNB1, ACTN4, HIF1A, SIRT1 |
nuclear localization sequence binding | molecular_function | IPO13 |
nuclease activity | molecular_function | APEX1, ANG, DICER1, PMS2, ISG20 |
nucleic acid binding | molecular_function | EGR1, BCL6, ATF2, TIA1, WT1, ZEB1, ANG, KLF11, SNAI1, MSI1, KHDRBS3, PRDM1, YBX1, DICER1, ELAVL1, FOXP3, ZNF366, KLF10, KLF9, PPRC1, RBM43, CHD5, ISG20 |
nucleic acid binding transcription factor activity | molecular_function | GATA3 |
nucleoside binding | molecular_function | ACTN4, PNP |
nucleoside diphosphate kinase activity | molecular_function | NME1 |
nucleosomal DNA binding | molecular_function | HMGA2, HDAC2, ACTB, HDAC1, MBD2 |
nucleosome binding | molecular_function | ARID1A |
nucleotide binding | molecular_function | GCLC, GSK3B, MSH2, MSH6, HSPD1, ATP5A1, FGFR1, SRC, MET, MAPK1, FGFR2, CFTR, KIT, AKT1, ERBB3, NME1, CLCN3, KDR, FLT4, HSPA6, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, TIA1, PIK3CA, FLT3, MTOR, MAT2A, HSPA4, MKI67, CHEK2, XRCC3, AURKA, ATP5B, INSR, HSP90AA1, EGFR, RHOC, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, ABCC4, MSI1, KALRN, DIRAS3, PAK4, NRAS, KRAS, CSF1R, ABCB1, CDC42, RAC1, PLK1, PTK2, DICER1, NTRK2, TYRO3, ACTB, TEK, PAK1, ACLY, NOD2, ATP7A, ELAVL1, MST1R, ATM, NOD1, LIMK1, DAPK1, PIM2, AMHR2, ABCG2, TRPV1, RND3, Sep-09, PPRC1, RBM43, CHD5, ATAD3A, FHIT, RHOA, RERG |
nucleotidyltransferase activity | molecular_function | TERT, GALT |
O-methyltransferase activity | molecular_function | COMT |
oligosaccharide binding | molecular_function | SELP, SELE |
oligosaccharyl transferase activity | molecular_function | DAD1 |
omega peptidase activity | molecular_function | UCHL1 |
oncostatin-M receptor activity | molecular_function | IL6ST, LIFR |
opioid receptor activity | molecular_function | OPRM1 |
opsonin binding | molecular_function | ITGAV |
organic anion transmembrane transporter activity | molecular_function | SLC22A23 |
ornithine decarboxylase activator activity | molecular_function | PRLR |
oxalate transmembrane transporter activity | molecular_function | SLC26A8 |
oxidized purine DNA binding | molecular_function | MSH2, MSH6, OGG1 |
oxidized purine nucleobase lesion DNA N-glycosylase activity | molecular_function | OGG1 |
oxidoreductase activity | molecular_function | XDH, AKR1B1, NDUFS1, AKR1D1, NOS2, PRDX6, APEX1, ALOX15, GPX3, CYP19A1, HPGD, MTHFR, CYP2A6, HMOX1, HSD3B2, HSD17B1, IDO1, CYP2B6, MAOA, LPO, PTGS1, NOS3, HMOX2, SRD5A2, CYP2C19, PTGS2, HSD17B3, HSD17B2, AKR1C3, ALDH3A2, AKR1C2, CYP17A1, MT-CO2, CYP2E1, CYP11A1, SOD1, CYP1A2, CYP26A1, CP, GPX1, CAT, CYP1A1, MPO, ADI1, LOXL4, AKR1C1, HSD17B7, HSD11B2, LOXL1, CYP1B1, TET3, SRD5A1, CYP24A1, TET2, TET1 |
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | molecular_function | TXN |
oxidoreductase activity, acting on CH-OH group of donors | molecular_function | XDH |
oxidoreductase activity, acting on diphenols and related substances as donors | molecular_function | CYP1A1 |
oxidoreductase activity, acting on NAD(P)H | molecular_function | NDUFS1 |
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2C19, CYP17A1, CYP2E1, CYP11A1, CYP1A2, CYP26A1, CYP1A1, CYP1B1, CYP24A1 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | molecular_function | TET3, TET2, TET1 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | molecular_function | CYP2E1, CYP11A1 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2E1, CYP1A2, CYP1A1, CYP1B1 |
oxidoreductase activity, acting on peroxide as acceptor | molecular_function | CAT, PARK7 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | molecular_function | ALOX15, PTGS2 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors | molecular_function | XDH |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | molecular_function | ALDH3A2 |
oxidoreductase activity, acting on the CH-CH group of donors | molecular_function | SRD5A2, SRD5A1 |
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | molecular_function | LOXL4, LOXL1 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | molecular_function | HSD3B2 |
oxygen binding | molecular_function | CYP19A1, CYP2B6, CYP2C19, CYP17A1, CYP2E1, CYP1A2, CYP26A1, CYP1A1, CYP1B1 |
oxytocin receptor activity | molecular_function | OXTR |
p53 binding | molecular_function | GSK3B, HSPD1, MUC1, TP53, SIRT1, EHMT2, CDKN2A, TP63 |
patched binding | molecular_function | CCNB1, IHH |
PDZ domain binding | molecular_function | GJA1, CFTR, CLCN3, PTEN, ADAM17, CADM1, MUC17 |
peptidase activator activity | molecular_function | FBLN1, MMP14, FN1 |
peptidase activity | molecular_function | MME, MMP13, MMP9, CASP1, ACE, CASP3, UCHL1, MMP7, MMP10, MMP14, CMA1, MMP11, MMP12, PLAT, LTF, CAPN5, CTSB, PLAU, MMP1, CTSD, KLK3, MMP2, MMP3, CTSG, COPS5, PARK7, ADAM17, PCSK5, ADAM8, BLMH, TPSAB1, FOLH1, PAPPA, IHH, HTRA1, CPB2, MMP24, TPSB2 |
peptidase inhibitor activity | molecular_function | TIMP2, TIMP3, A2M, SERPINA1, NGF, TIMP1, BIRC5, SLPI, SERPINE1, SPINK1, SERPINB2, WFDC2, TIMP4 |
peptide alpha-N-acetyltransferase activity | molecular_function | NAA15 |
peptide antigen binding | molecular_function | HLA-DRB1, HLA-C, AZGP1, HLA-E, HLA-G, HLA-A, HLA-B, HLA-DQA1, HLA-DPB1, HLA-DRA |
peptide binding | molecular_function | MME, CRHBP, CMA1, OXTR, ITGB1, ANG, CTSB, PCSK5 |
peptide disulfide oxidoreductase activity | molecular_function | TXN |
peptide hormone binding | molecular_function | INHBA, ANXA5, AGTR2, PRLR, OXTR, CRHR2 |
peptide hormone receptor binding | molecular_function | LEP, FYN |
peptidoglycan binding | molecular_function | TLR2, NOD2, NOD1 |
peptidyl-dipeptidase activity | molecular_function | ACE |
peptidyl-prolyl cis-trans isomerase activity | molecular_function | FKBP4, FKBP5 |
peroxidase activity | molecular_function | PRDX6, GPX3, LPO, PTGS1, PTGS2, GPX1, CAT, MPO |
peroxiredoxin activity | molecular_function | PRDX6, PARK7 |
peroxisome proliferator activated receptor binding | molecular_function | HMGA1, ESR2, NR0B2 |
phenanthrene 9,10-monooxygenase activity | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
phenylpyruvate tautomerase activity | molecular_function | MIF |
phosphatase activity | molecular_function | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR |
phosphatase binding | molecular_function | MAPK1, SMAD3, SMAD2, PPARA |
phosphate ion binding | molecular_function | PNP, RELA |
phosphatidic acid binding | molecular_function | PLCD1 |
phosphatidyl-N-dimethylethanolamine N-methyltransferase activity | molecular_function | PEMT |
phosphatidyl-N-methylethanolamine N-methyltransferase activity | molecular_function | PEMT |
phosphatidylcholine 1-acylhydrolase activity | molecular_function | PLA2G4A, LIPC, PLA2G16 |
phosphatidylcholine binding | molecular_function | CETP, APOA1, APOA2 |
phosphatidylcholine-sterol O-acyltransferase activator activity | molecular_function | APOA1, APOA2, APOE |
phosphatidylethanolamine binding | molecular_function | PEMT |
phosphatidylethanolamine N-methyltransferase activity | molecular_function | PEMT |
phosphatidylinositol 3-kinase activity | molecular_function | PIK3CA |
phosphatidylinositol 3-kinase binding | molecular_function | PIK3R1, INSR, IGF1R, FYN, TYRO3, IRS2 |
phosphatidylinositol 3-kinase regulator activity | molecular_function | PIK3R1 |
phosphatidylinositol 3-kinase regulatory subunit binding | molecular_function | PIK3R1, ESR1 |
phosphatidylinositol phosphate binding | molecular_function | PLCD1 |
phosphatidylinositol phospholipase C activity | molecular_function | CCL5, PLCD1, CCR1, CCR5, EDNRA, PLCB1, PLCB3, PLCD3 |
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | molecular_function | PTEN |
phosphatidylinositol-3,4,5-trisphosphate binding | molecular_function | AKT1 |
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | molecular_function | PTEN |
phosphatidylinositol-3,4-bisphosphate binding | molecular_function | AKT1 |
phosphatidylinositol-3-phosphatase activity | molecular_function | PTEN |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity | molecular_function | FGFR1, FGF2, FGFR2, PIK3R1, KIT, ERBB3, PDGFRA, KITLG, PIK3CA, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, NRG1, IRS2 |
phosphatidylinositol-4,5-bisphosphate binding | molecular_function | ALOX15, ANXA2, PLCB1 |
phosphatidylserine 1-acylhydrolase activity | molecular_function | PLA2G16 |
phosphatidylserine binding | molecular_function | HMGB1, PLCD1, AXL, THBS1, GAS6, SCARB1 |
phosphodiesterase I activity | molecular_function | APEX1 |
phosphoglucomutase activity | molecular_function | PGM1 |
phospholipase A2 activator activity | molecular_function | CASP3 |
phospholipase A2 activity | molecular_function | PLA2G4A, PLA2G2A, RARRES3, PLA2G16, PAFAH1B2 |
phospholipase A2 inhibitor activity | molecular_function | ANXA1, ANXA2 |
phospholipase activator activity | molecular_function | CCL5, CCL3 |
phospholipase activity | molecular_function | PLA2G4A, LIPC |
phospholipase binding | molecular_function | SELE |
phospholipase C activity | molecular_function | PLCD1, PLCB3 |
phospholipase D activity | molecular_function | HMOX1 |
phospholipase inhibitor activity | molecular_function | ANXA5, ANXA4, ANXA1, ANXA2 |
phospholipid binding | molecular_function | F3, ANXA5, SHC1, PLA2G2A, PON1, ANXA1, APOA1, APOA2, APOE, NR5A2, NR5A1, LPAR3 |
phospholipid transporter activity | molecular_function | CETP, APOA1 |
phosphoprotein binding | molecular_function | SRC, IGF2R, SHC1, MTOR, PLAT, RB1, FKBP4, TRPV1 |
phosphoprotein phosphatase activity | molecular_function | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR, ILKAP |
phosphopyruvate hydratase activity | molecular_function | ENO2, ENO1 |
phosphoric diester hydrolase activity | molecular_function | APEX1, PLCD1, PLCB1, PLCB3, PLCD3 |
phosphorylase activity | molecular_function | TYMP |
phosphotyrosine binding | molecular_function | MAPK1, SHC1 |
placental growth factor-activated receptor activity | molecular_function | FLT1 |
platelet-activating factor acetyltransferase activity | molecular_function | PAFAH1B2 |
platelet-derived growth factor alpha-receptor activity | molecular_function | PDGFRA |
platelet-derived growth factor binding | molecular_function | PDGFRA, PDGFA, COL4A1 |
platelet-derived growth factor receptor binding | molecular_function | VEGFA, PDGFRA, IL1R1, TYMP, ITGB3, PDGFA, FIGF, PTEN |
poly(A) binding | molecular_function | TIA1 |
poly(A) RNA binding | molecular_function | HSPD1, ATP5A1, TXN, HMGB1, LGALS3, APEX1, NME1, CDKN2A, CTNNA1, STIP1, LGALS1, TIA1, MKI67, HSP90AA1, JUN, ACTN4, HSPB1, ENO1, MSI1, ANXA2, KHDRBS3, C4BPA, YBX1, HDAC2, EIF3E, FKBP4, POU5F1, ELAVL1, NAA15, PPRC1, DCN |
poly(U) RNA binding | molecular_function | MSI1 |
potassium channel regulator activity | molecular_function | DPP6, DRD2, SGK1, PIAS3 |
pre-miRNA binding | molecular_function | DICER1 |
prenylated protein tyrosine phosphatase activity | molecular_function | PTP4A3 |
primary amine oxidase activity | molecular_function | VCAM1, MAOA |
prolactin receptor activity | molecular_function | PRLR |
prolactin receptor binding | molecular_function | PRL |
proline-rich region binding | molecular_function | YAP1, CCND1 |
promoter-specific chromatin binding | molecular_function | DNMT1, EZH2, EHMT2 |
prostaglandin D2 11-ketoreductase activity | molecular_function | AKR1C3 |
prostaglandin E receptor activity | molecular_function | HPGD, PTGER4, PTGER3, PTGER2 |
prostaglandin F receptor activity | molecular_function | PTGFR |
prostaglandin H2 endoperoxidase reductase activity | molecular_function | AKR1C3 |
prostaglandin receptor activity | molecular_function | PPARG, PTGER4, PTGER3 |
prostaglandin transmembrane transporter activity | molecular_function | SLCO2A1 |
prostaglandin-D synthase activity | molecular_function | PTGDS |
prostaglandin-E synthase activity | molecular_function | PTGES, PTGES2 |
prostaglandin-endoperoxide synthase activity | molecular_function | PTGS1, PTGS2 |
prostaglandin-F synthase activity | molecular_function | AKR1C3 |
protease binding | molecular_function | BCL2, ITGA3, F3, KIT, CASP3, BRCA2, IL1R1, FAS, TIMP2, TIMP3, FN1, ITGB3, ITGB1, ITGAV, A2M, SERPINA1, TIMP1, TP53, TNF, ANXA2, SERPINE1, TIMP4 |
proteasome binding | molecular_function | ID1 |
protein anchor | molecular_function | PDCD6 |
protein antigen binding | molecular_function | KLRC1, KLRD1 |
protein binding | molecular_function | GSK3B, MSH2, MSH6, H2AFX, MLH1, CRK, BCL2, HSPD1, NDUFS1, PGM1, ATP5A1, FGFR1, EGR1, SRC, TXN, CDH1, GATA3, ITGA6, INHBA, YAP1, FGF2, CCND1, VEGFA, FSHR, MET, BCL6, STAT3, NOS2, NR2F2, BMP4, CRHR1, DNMT1, PCNA, CDX1, CD40LG, F2R, WNT5A, MME, HMGA2, ITGA3, PTGDS, PPARG, TNFRSF1A, PRDX6, CCL5, FBLN1, MAPK1, FGFR2, IGF2R, HMGB1, LGALS3, IGFBP2, CLU, GJA1, CFTR, IGFBP3, APEX1, PIK3R1, CD36, ALOX15, F3, GPX3, IL10, KIT, IL12B, VIM, MMP9, CXCL8, OPRM1, MIF, ANXA5, AKT1, SHC1, CTNNB1, CCNB1, ATF2, EPCAM, CFL1, BRCA1, PTGER4, CCL3, SERPINF1, SLC6A4, NFKB1, HMGA1, CASP1, AR, TOB1, KRT19, WNT2, MBL2, TNFSF10, AHR, ERBB3, CDKN1B, NOTCH1, NME1, ACE, DRD2, CLCN3, KDR, ID1, FPR1, CASP3, RASSF2, FASLG, SPP1, CSF1, SDC4, CCR1, CCR5, FLT4, UCHL1, CDKN1A, CSF2RB, HSPA6, CDKN2A, VDR, TNFRSF1B, CD40, BRAF, XRCC1, MUC1, CTNNA1, STIP1, PDGFRA, AXL, AGTR1, AGTR2, ANXA4, ENG, PRLR, COL4A2, BRCA2, FST, HLA-DRB1, S100P, JAK1, IGFBP5, IL6R, IL6ST, EDNRA, ITGA2, ITGB5, CRHBP, GATA2, LAMA1, SPARC, TYK2, LGALS1, HGF, FLT1, KRT7, CNTF, ENO |
protein binding involved in protein folding | molecular_function | CD74 |
protein binding, bridging | molecular_function | CRK, ANXA1, FGA, FKBP4 |
protein C-terminus binding | molecular_function | MSH2, SRC, YAP1, FBLN1, VIM, OPRM1, CTNNB1, ID1, STIP1, SDC1, MKI67, ERBB2, MAP2K7, XRCC4, SIRT1, KSR1, PIAS3 |
protein channel activity | molecular_function | MCL1 |
protein complex binding | molecular_function | FGFR1, SRC, CCND1, FBLN1, APEX1, SHC1, CTNNB1, EPCAM, MTHFR, KRT19, CDKN1B, CASP3, CDKN1A, ITGA2, FAS, HNF1B, FLT3, ESR1, INSR, ITGB1, ACTN4, MYC, FYN, CTSB, ITGB2, NRAS, KRAS, ICAM1, RELA, HIF1A, BAX, PPARA, KAT2B, ATM, NR0B2 |
protein deacetylase activity | molecular_function | HDAC2, HDAC1, SIRT1 |
protein dimerization activity | molecular_function | GATA3, STAT3, AR, AHR, ID1, USF1, ARNT, CLOCK, MYC, ERBB2, PDCD6, HPSE, HIF1A, HES5, HEY1, ID2, ATM, TWIST1, ABCG2, USF2, AHRR |
protein disulfide isomerase activity | molecular_function | ITGB3 |
protein disulfide oxidoreductase activity | molecular_function | TXN, PTGES2 |
protein domain specific binding | molecular_function | CRK, SRC, DNMT1, WNT5A, ITGA3, GJA1, OPRM1, MTOR, INSR, ITGB1, IL1B, WNT1, DICER1, PLAUR, NFE2L2, PPARA, SIRT1, YWHAH, TWIST1, NR0B2, TP63, IRS2, MBD2 |
protein heterodimerization activity | molecular_function | GCLC, H2AFX, BCL2, INHBA, VEGFA, ITGA3, PIK3R1, IL12B, ATF2, NFKB1, AHR, ERBB3, NOTCH1, DRD2, CLCN3, BRAF, AXL, AGTR1, ITGA2, HGF, USF1, LIFR, HNF1B, BMP6, ARNT, IL12A, ITGB1, EGFR, JUN, TGFB1, INHA, TP53, APOA2, PDGFA, BIRC5, TLR2, ENO1, ERBB2, MEIS1, SOX15, FOS, CXCL13, ITGB2, TGFB2, SMAD3, RELA, BCL2L1, HIF1A, TYRO3, BAX, SMAD2, MCL1, NECTIN1, SMAD4, LIMK1, HIST3H3, YWHAH, TWIST1, NECTIN3, HIST2H3A, USF2, PAFAH1B2, NOTCH4, ADIPOR2, ADIPOR1 |
protein homodimerization activity | molecular_function | MSH2, MSH6, XDH, BCL2, FGFR1, VEGFA, NOS2, NR2F2, BMP4, CCL5, FGFR2, KIT, IL12B, HPGD, SLC6A4, NFKB1, ERBB3, DRD2, CLCN3, ID1, CSF1, PDGFRA, ENG, PRLR, IL6R, IL6ST, LGALS1, GSTM1, HMOX1, USF1, HLA-G, HNF1B, PON1, FLT3, PTGS2, CCR2, CHEK2, GSTZ1, HSP90AA1, JUN, ANG, CRYAB, TGFB1, ACTN4, ANXA1, SOD1, S100A6, APOA2, APOE, TERT, PDGFA, BIRC5, CD4, PDCD6, FIGF, AGR2, CAT, CSF1R, TGFB2, SMAD3, RELA, BCL2L1, PARK7, NTRK2, BAX, PLCB1, S100A13, SMAD2, ADIPOQ, MCL1, ELAVL1, NECTIN1, FOXP3, NOD1, SMAD4, TWIST1, NECTIN3, CADM1, SCARB1, NR0B2, ABCG2, USF2, PAFAH1B2, NECTIN4, OLFM4, CADM2, IL17F, KLRK1, LILRB1 |
protein kinase A catalytic subunit binding | molecular_function | GSK3B |
protein kinase activator activity | molecular_function | HMGB1, PIK3CA |
protein kinase activity | molecular_function | GSK3B, FGFR1, SRC, CCND1, MET, CCL5, MAPK1, FGFR2, KIT, AKT1, CCL3, ERBB3, KDR, RASSF2, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, CCL2, FLT3, MTOR, CHEK2, AURKA, INSR, EGFR, MAP3K7, IGF1R, PRKCB, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, CSF1R, PLK1, PTK2, NTRK2, TYRO3, TEK, PAK1, MST1R, ATM, LIMK1, DAPK1, PIM2, AMHR2, KSR1 |
protein kinase binding | molecular_function | GSK3B, MSH2, SRC, CCND1, STAT3, MAPK1, AKT1, CTNNB1, CCNB1, ATF2, NME1, CDKN2A, USF1, MTOR, CCR2, CHEK2, AURKA, INSR, ITGB1, HSP90AA1, TP53, HSPB1, CD4, LATS1, MAP2K7, SPRY2, ITGB2, CDC42, RAC1, PTEN, PLK1, PTK2, SMAD3, RELA, BCL2L1, HIF1A, DPYSL2, PAK1, NOD2, KAT2B, ELAVL1, ERRFI1, GATA6, IRS2, PTPRR, ADIPOR1 |
protein kinase C activity | molecular_function | PRKCB |
protein kinase C binding | molecular_function | SRC, AKT1, SDC4, ITGAV, PRKCB, HSPB1, C1QBP |
protein kinase C inhibitor activity | molecular_function | HSPB1 |
protein kinase inhibitor activity | molecular_function | BGN, CDKN1B, CDKN1A, SOCS3, DCN |
protein N-terminus binding | molecular_function | CLU, ID1, TGFB1, ACTN4, TP53, SUV39H1, RELA, EIF3E, HDAC1, ATM, STX5, DCN, PIAS3 |
protein phosphatase 1 binding | molecular_function | LILRB1 |
protein phosphatase 2A binding | molecular_function | BCL2, AKT1, SHC1, TP53, FOXO1, EIF4EBP1 |
protein phosphatase 2B binding | molecular_function | SOD1 |
protein phosphatase binding | molecular_function | BCL2, MET, STAT3, PPARG, PIK3R1, CTNNB1, CDKN1B, FLT4, JAK1, STAT6, INSR, HSP90AA1, EGFR, TP53, ERBB2, MAP2K7, CSF1R, IRS2 |
protein phosphatase inhibitor activity | molecular_function | PTN, SET |
protein phosphorylated amino acid binding | molecular_function | CRK |
protein self-association | molecular_function | CCL5, ID1, TP53, CTSB, SYP, FOXP1, ADAM8 |
protein serine/threonine kinase activator activity | molecular_function | TGFB1, LTF, SPRY2, IGF2 |
protein serine/threonine kinase activity | molecular_function | GSK3B, MAPK1, AKT1, BRAF, PIK3CA, MTOR, CHEK2, AURKA, MAP3K7, PRKCB, LATS1, SGK1, BMPR1B, MAP2K7, KALRN, PAK4, PLK1, PAK1, ATM, LIMK1, DAPK1, PIM2, AMHR2 |
protein serine/threonine kinase inhibitor activity | molecular_function | SPRY2 |
protein serine/threonine phosphatase activity | molecular_function | PTEN, ILKAP |
protein serine/threonine/tyrosine kinase activity | molecular_function | AKT1, AURKA, SGK1 |
protein transmembrane transporter activity | molecular_function | AZGP1 |
protein transporter activity | molecular_function | IPO13 |
protein tyrosine kinase activator activity | molecular_function | ERBB3, NRG1, GAS6, GHRL |
protein tyrosine kinase activity | molecular_function | FGFR1, SRC, FGF2, MET, FGFR2, KIT, ERBB3, KDR, FLT4, CSF2RB, PDGFRA, AXL, JAK1, TYK2, FLT1, FLT3, INSR, HSP90AA1, EGFR, FGF1, IGF1R, ERBB2, FYN, MAP2K7, EGF, CSF2, IL5, CSF1R, PTK2, NRG1, NTRK2, TYRO3, TEK, MST1R |
protein tyrosine kinase binding | molecular_function | CD4 |
protein tyrosine phosphatase activator activity | molecular_function | IGFBP3 |
protein tyrosine phosphatase activity | molecular_function | ACP1, PTP4A3, PTEN, PTPN22, DUSP2, PTPRR |
protein tyrosine/serine/threonine phosphatase activity | molecular_function | PTP4A3, PTEN, DUSP2 |
protein tyrosine/threonine phosphatase activity | molecular_function | DUSP2 |
protein xylosyltransferase activity | molecular_function | XYLT2 |
protein-hormone receptor activity | molecular_function | FSHR, LHCGR |
protein-lysine N-methyltransferase activity | molecular_function | EZH2, EHMT2 |
proteoglycan binding | molecular_function | PTN, THBS1, CTSB |
proton-transporting ATP synthase activity, rotational mechanism | molecular_function | ATP5A1, ATP5B |
proton-transporting ATPase activity, rotational mechanism | molecular_function | ATP5A1, ATP5B |
PTB domain binding | molecular_function | INSR |
purine nucleobase binding | molecular_function | PNP |
purine nucleoside binding | molecular_function | ADA |
purine-nucleoside phosphorylase activity | molecular_function | PNP |
purine-specific mismatch base pair DNA N-glycosylase activity | molecular_function | PCNA |
purinergic nucleotide receptor activity | molecular_function | P2RX3 |
pyrimidine-nucleoside phosphorylase activity | molecular_function | TYMP |
R-SMAD binding | molecular_function | JUN, FOS, SMAD3, SMAD2, SMAD4 |
Rab GTPase binding | molecular_function | SLC6A4, ANXA2, RAC1 |
Rac GTPase binding | molecular_function | SOD1 |
RAGE receptor binding | molecular_function | HMGB1, FPR1, S100P, S100A13 |
Ran GTPase binding | molecular_function | BIRC5, CSE1L, IPO13 |
Ras guanyl-nucleotide exchange factor activity | molecular_function | FGFR1, FGF2, FGFR2, KIT, SHC1, ERBB3, CSF2RB, PDGFRA, JAK1, KITLG, NCAM1, IL2RB, EGFR, FGF1, PDGFA, ERBB2, FYN, EGF, IL2RA, CSF2, IL5, PTK2, NRG1, TEK, IRS2, IL2, ANGPT1 |
receptor activator activity | molecular_function | ANXA2, IGF2 |
receptor activity | molecular_function | FOLR1, IGF2R, NOTCH1, FPR1, CXCR3, CSF2RB, CD40, ITGB5, FAS, ITGB6, MRC1, KIR2DL1, KIR2DL3, ITGB3, ITGB1, TLR2, TLR4, CD4, TNFRSF11B, TLR3, NRP2, ITGB2, KRT1, ICAM1, PLAUR, TEK, F2RL1, PPARA, NECTIN1, AGER, NECTIN3, CADM1, AMHR2, IL10RB, NECTIN4, NOTCH4, CADM2, KLRK1, ADIPOR2, ADIPOR1 |
receptor agonist activity | molecular_function | VEGFA, WNT5A, WNT2, GREM1, WNT7A, CXCL13, WNT1, GAS6, WNT4, NODAL |
receptor antagonist activity | molecular_function | AGTR2, DKK1, ESR2 |
receptor binding | molecular_function | SRC, INHBA, FGF2, NOS2, F2R, WNT5A, IGFBP2, GJA1, LEP, MIF, AR, WNT2, MBL2, TNFSF10, DRD2, FASLG, JAK1, LAMA1, IGFBP1, CXCL1, TDGF1, CCL2, HLA-E, LIF, HLA-G, EFNA1, IGFBP4, BDNF, NTF4, ADM, CXCL12, ITGB1, FGF1, ANG, ANXA1, A2M, FGA, PLAT, INHA, NGF, CXCL10, C3, FYN, WNT7A, MSTN, ANGPT2, LAMA5, SERPINE1, PGR, IL1B, C5, LHB, LTA, HLA-B, AMH, CAT, WNT1, IL6, EDN1, CRH, TGFB2, PTK2, NRG1, PARK7, GAS6, PLAUR, F2RL1, STOML2, ADIPOQ, RARRES2, NECTIN1, TNFSF13B, NECTIN3, CADM1, CX3CL1, WNT4, HAMP, ANGPT1, NECTIN4, CADM2, IL27, CCL17, NPY, UCN2 |
receptor signaling protein tyrosine kinase activator activity | molecular_function | CCL5 |
receptor tyrosine kinase binding | molecular_function | PCNA, ANXA5, SHC1, TOB1, TP53, ANGPT2, NRG1, NTRK2, GAS6, ANGPT1, MST1 |
receptor tyrosine kinase-like orphan receptor binding | molecular_function | WNT5A |
recombinase activity | molecular_function | XRCC3 |
regulatory region DNA binding | molecular_function | HMGA2, NFKB1, EZH2 |
repressing transcription factor binding | molecular_function | HMGB1, CTNNB1, MYC, RELA, PARK7, HDAC1 |
retinal binding | molecular_function | RBP1 |
retinal dehydrogenase activity | molecular_function | AKR1C3 |
retinoic acid 4-hydroxylase activity | molecular_function | CYP26A1 |
retinoic acid binding | molecular_function | NR2F2, IGF2R, CYP26A1 |
retinoic acid receptor binding | molecular_function | HMGA1, ACTN4, NR0B2 |
retinoid binding | molecular_function | PTGDS, RBP1 |
retinoid X receptor binding | molecular_function | PPARG, HMGA1, VDR, NR0B2 |
retinol binding | molecular_function | RBP1 |
retinol dehydrogenase activity | molecular_function | AKR1C3 |
Rho GDP-dissociation inhibitor binding | molecular_function | HSP90AA1, CDC42, RAC1 |
Rho guanyl-nucleotide exchange factor activity | molecular_function | KALRN |
ribonuclease activity | molecular_function | AZGP1, ANG |
ribonuclease III activity | molecular_function | DICER1 |
ribonucleoprotein complex binding | molecular_function | EZH2 |
ribosomal small subunit binding | molecular_function | NME1 |
ribosome binding | molecular_function | MTOR, NAA15 |
RNA binding | molecular_function | DNMT1, APEX1, BRCA1, TIA1, WT1, TERT, ENO1, TLR3, NR3C1, MSI1, ANXA2, KHDRBS3, YBX1, DICER1, PARK7, ELAVL1, EZH2, RPL41, PPRC1, RBM43, ISG20 |
RNA polymerase I core binding | molecular_function | ERBB2 |
RNA polymerase II activating transcription factor binding | molecular_function | CTNNB1, ATF2, JUN, RB1, SMAD3, NFE2L2 |
RNA polymerase II carboxy-terminal domain kinase activity | molecular_function | MAPK1 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | molecular_function | STAT3, AR, MUC1, HOXA10, ESR1, JUN, CLOCK, MYC, MEIS1, NR5A2, FOS, NR3C1, PRDM1, PGR, YBX1, HDAC2, SMAD3, RELA, FOXL2, ACTB, HSF1, SMAD2, PPARA, NFKB2, HDAC1, SMAD4, DLX5, MBD2 |
RNA polymerase II core promoter sequence-specific DNA binding | molecular_function | GATA3, YAP1, GATA2, STAT6, FOS, HSF1, GATA6 |
RNA polymerase II distal enhancer sequence-specific DNA binding | molecular_function | CDX1, ATF2, NFKB1, GATA2, JUN, NR5A2, HDAC2, RELA, ACTB, NR5A1, NFE2L2, HDAC1, MBD2 |
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | molecular_function | HSF1 |
RNA polymerase II regulatory region sequence-specific DNA binding | molecular_function | EGR1, GATA3, BCL6, ATF2, NFKB1, NME1, GATA2, ACTN4, SNAI1, RUNX3, SMAD3, RELA, KAT2B, STAT4, SMAD4, GATA6, GATA5 |
RNA polymerase II repressing transcription factor binding | molecular_function | STAT3, HDAC2, PPARA, HDAC1, GATA6 |
RNA polymerase II transcription cofactor activity | molecular_function | PPRC1 |
RNA polymerase II transcription corepressor activity | molecular_function | HDAC1 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | molecular_function | ESR1, ESR2 |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | molecular_function | STAT3, NR2F2, PPARG, AR, AHR, VDR, PTGER3, ESR1, NR5A2, NR5A1, ESR2, PPARA |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | molecular_function | STAT3, JUN, TP53, SOX15, KLF11, RUNX3, FOXL2, HIF1A, FOXP1, FOXO1, POU5F1, FOXP3, TWIST1, GATA6 |
RNA polymerase II transcription factor binding | molecular_function | GSK3B, GATA3, CTNNB1, AR, GATA2, TP53, HDAC1, SMAD4, GATA6, GATA5 |
RNA polymerase III type 1 promoter DNA binding | molecular_function | MTOR |
RNA polymerase III type 2 promoter DNA binding | molecular_function | MTOR |
RNA polymerase III type 3 promoter DNA binding | molecular_function | MTOR |
RNA-directed 5'-3' RNA polymerase activity | molecular_function | TERT |
RNA-directed DNA polymerase activity | molecular_function | TERT |
RNA-DNA hybrid ribonuclease activity | molecular_function | APEX1 |
Roundabout binding | molecular_function | TGFB1I1 |
rRNA binding | molecular_function | ANG |
S-adenosylmethionine-dependent methyltransferase activity | molecular_function | SUV39H1, PEMT |
S-nitrosoglutathione binding | molecular_function | GSTP1 |
S100 protein binding | molecular_function | FGF1, S100A6, ANXA2, AGER |
satellite DNA binding | molecular_function | MBD2 |
scaffold protein binding | molecular_function | SRC, GJA1, VIM, NOS3, MAP3K7, PARK7 |
scavenger receptor activity | molecular_function | LOXL4, CXCL16 |
secondary active sulfate transmembrane transporter activity | molecular_function | SLC26A8 |
selenium binding | molecular_function | GPX3 |
semaphorin receptor activity | molecular_function | NRP1, NRP2 |
semaphorin receptor binding | molecular_function | SEMA3A, SEMA3C |
sequence-specific DNA binding | molecular_function | BCL2, EGR1, GATA3, BCL6, STAT3, NR2F2, CDX1, PPARG, ATF2, NFKB1, AR, NOTCH1, VDR, GATA2, USF1, HOXB2, STAT6, HOXA10, WT1, HNF1B, ARNT, HOXA11, SOX2, ESR1, JUN, CLOCK, TP53, MEIS1, NR5A2, SNAI1, FOS, NR3C1, PRDM1, PGR, HDAC2, SMAD3, RELA, FOXL2, HIF1A, FOXP1, FOXO1, NR5A1, HSF1, NFE2L2, ESR2, PPARA, POU5F1, FOXP3, EZH2, SMAD4, TP63, EMX2, GATA6, USF2, DLX5, NANOG, GATA5, MAF, CREB3L1 |
serine-type endopeptidase activity | molecular_function | MMP13, MMP9, MBL2, HGF, MMP7, MMP10, C4A, MMP14, CMA1, MMP11, MMP12, PLAT, LTF, C3, CTSB, PLAU, MMP1, CTSD, KLK3, MMP2, MMP3, CTSG, PCSK5, ADAM8, TPSAB1, HTRA1, TPSB2, MST1 |
serine-type endopeptidase inhibitor activity | molecular_function | SERPINF1, SERPINA6, A2M, SERPINA1, SLPI, SERPINE1, SPINK1, SERPINB2, WFDC2 |
serine-type peptidase activity | molecular_function | DPP6, CMA1, PLAT, LTF, PLAU, KLK3, CTSG, PCSK5, TPSAB1, HTRA1, TPSB2 |
serotonin binding | molecular_function | MAOA |
serotonin transmembrane transporter activity | molecular_function | SLC6A4 |
serotonin:sodium symporter activity | molecular_function | SLC6A4 |
SH2 domain binding | molecular_function | CRK, SRC, SYP, PTK2, LILRB1 |
SH3 domain binding | molecular_function | GJA1, KHDRBS3, GPX1, ERRFI1, PTPN22, ADAM17 |
SH3/SH2 adaptor activity | molecular_function | CRK, SRC, TOB1, GRB14 |
sialic acid binding | molecular_function | SELP, SELE, ADIPOQ |
signal transducer activity | molecular_function | FSHR, STAT3, CRHR1, F2R, GJA1, OPRM1, CTNNB1, PTGER4, DRD2, FPR1, PLCD1, CCR1, CCR5, CXCR3, CD40, AGTR1, AGTR2, FST, EDNRA, LGALS1, HMOX1, IL1R1, CXCR1, CXCR2, FAS, STMN1, STAT6, TACR2, TACR1, LHCGR, OXTR, SSTR1, SSTR5, CCR2, PTGFR, PTGER3, PTGER2, CCR9, EGFR, RHOC, LGR5, LGALS9, CXCR6, DKK1, PTK2, PLCB1, CXCR4, F2RL1, GPER1, IRS2, PLCB3, KISS1R, CRHR2, IL11RA, PLCD3, HRH4, IL1RAP, LPAR3, CCR7, CCR8, RXFP1 |
signal transducer activity, downstream of receptor | molecular_function | BRAF, NCR1, IL1RL1 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity | molecular_function | KIT, KDR, INSR, EGFR, ERBB2, TYRO3 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | molecular_function | BMPR1B, MAP2K7, PAK4, TGFB2, PAK1, AMHR2 |
signaling pattern recognition receptor activity | molecular_function | TLR2 |
single base insertion or deletion binding | molecular_function | PMS2 |
single guanine insertion binding | molecular_function | MSH2, MSH6 |
single thymine insertion binding | molecular_function | MSH2, MSH6 |
single-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular_function | ISG20 |
single-stranded DNA binding | molecular_function | MSH2, MLH1, HSPD1, HMGB1, NME1, BRCA2, XRCC3, ANXA1, YBX1, PARK7, PMS2 |
single-stranded RNA binding | molecular_function | HMGB1, ANXA1, MSI1 |
siRNA binding | molecular_function | DICER1, TLR9, MBD2 |
site-specific endodeoxyribonuclease activity, specific for altered base | molecular_function | APEX1 |
SMAD binding | molecular_function | HMGA2, CTNNB1, TOB1, BMPR1B, COL5A2, SMAD3, SMAD2 |
small GTPase binding | molecular_function | BRAF, ERRFI1 |
small molecule binding | molecular_function | PTGDS, PAEP |
small protein activating enzyme binding | molecular_function | PARK7 |
SNAP receptor activity | molecular_function | STX5 |
SNARE binding | molecular_function | STX5 |
sodium channel regulator activity | molecular_function | SGK1, YWHAH |
sodium-independent organic anion transmembrane transporter activity | molecular_function | SLCO2A1, SLCO4A1 |
somatostatin receptor activity | molecular_function | SSTR1, SSTR5 |
sphingomyelin phosphodiesterase activity | molecular_function | SMPD3 |
sphingosine-1-phosphate phosphatase activity | molecular_function | SGPP2 |
stem cell factor receptor activity | molecular_function | KIT |
stem cell factor receptor binding | molecular_function | KITLG |
steroid 17-alpha-monooxygenase activity | molecular_function | CYP17A1 |
steroid binding | molecular_function | AKR1D1, AR, ESR1, IGF1, SERPINA6, PGRMC1, PGRMC2, NR3C1, PGR, SHBG, ESR2, GPER1, HSD11B2, SULT1E1 |
steroid delta-isomerase activity | molecular_function | HSD3B2 |
steroid hormone binding | molecular_function | NR3C1, ESR2, GPER1 |
steroid hormone receptor activity | molecular_function | NR2F2, PPARG, VDR, ESR1, NR5A2, PGRMC2, NR3C1, PGR, NR5A1, ESR2, PPARA, GPER1, NR0B2 |
steroid hydroxylase activity | molecular_function | CYP19A1, CYP2A6, CYP2B6, CYP2C19, CYP2E1, CYP1A1 |
steroid sulfotransferase activity | molecular_function | SULT1E1 |
sterol 5-alpha reductase activity | molecular_function | SRD5A2 |
steryl-sulfatase activity | molecular_function | STS |
structural constituent of cytoskeleton | molecular_function | VIM, KRT19, ACTB |
structural constituent of eye lens | molecular_function | VIM, CRYAB |
structural constituent of muscle | molecular_function | KRT19 |
structural constituent of ribosome | molecular_function | RPL41 |
structural molecule activity | molecular_function | VIM, KRT19, CTNNA1, KRT7, MAP2, COL18A1, ANXA1, FGA, CLDN5, CLDN4, LAMA5, CLDN3, CLDN7, KRT1, JAG1 |
structure-specific DNA binding | molecular_function | TET1 |
substance K receptor activity | molecular_function | TACR2 |
substance P receptor activity | molecular_function | TACR1 |
sulfate transmembrane transporter activity | molecular_function | SLC26A8 |
sulfonylurea receptor binding | molecular_function | HSP90AA1 |
sulfotransferase activity | molecular_function | CHST6, CHST2, SULT1E1 |
sulfuric ester hydrolase activity | molecular_function | STS, ARSH |
SUMO transferase activity | molecular_function | CDKN2A, PIAS3 |
supercoiled DNA binding | molecular_function | HMGB1 |
superoxide dismutase activity | molecular_function | SOD1 |
superoxide dismutase copper chaperone activity | molecular_function | PARK7, ATP7A |
superoxide-generating NADPH oxidase activity | molecular_function | PAX2 |
symporter activity | molecular_function | SLC6A4, SLC6A2 |
syndecan binding | molecular_function | TNC, HPSE |
syntaxin-1 binding | molecular_function | SLC6A4, DAPK1 |
T cell receptor binding | molecular_function | FYN |
tachykinin receptor activity | molecular_function | TACR2, TACR1 |
TAP binding | molecular_function | HLA-A |
Tat protein binding | molecular_function | ACTB, GABARAPL1 |
tau protein binding | molecular_function | GSK3B, APOE, SGK1, FKBP4 |
tau-protein kinase activity | molecular_function | GSK3B |
telomerase activity | molecular_function | TERT |
telomerase RNA binding | molecular_function | TERT |
telomerase RNA reverse transcriptase activity | molecular_function | TERT |
telomeric DNA binding | molecular_function | TERT |
testosterone 17-beta-dehydrogenase (NADP+) activity | molecular_function | HSD17B3, AKR1C3 |
testosterone dehydrogenase (NAD+) activity | molecular_function | HSD17B1, HSD17B3, HSD17B2, AKR1C3 |
tetrahydrobiopterin binding | molecular_function | NOS2, NOS3 |
tetrahydrofolyl-poly(glutamate) polymer binding | molecular_function | FOLH1 |
TFIIIC-class transcription factor binding | molecular_function | MTOR |
thiocyanate peroxidase activity | molecular_function | LPO |
thioesterase binding | molecular_function | CDC42, RAC1 |
thiol-dependent ubiquitin-specific protease activity | molecular_function | UCHL1, COPS5 |
thiol-dependent ubiquitinyl hydrolase activity | molecular_function | UCHL1 |
thrombin-activated receptor activity | molecular_function | F2R, F2RL1 |
thrombospondin receptor activity | molecular_function | CD36, SDC4 |
thymidine phosphorylase activity | molecular_function | TYMP |
thyroid hormone receptor binding | molecular_function | NR0B2 |
thyroid hormone transmembrane transporter activity | molecular_function | SLCO4A1 |
Toll-like receptor binding | molecular_function | TLR2 |
TPR domain binding | molecular_function | HSP90AA1 |
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | molecular_function | AKR1C3, AKR1C2, AKR1C1 |
transcription coactivator activity | molecular_function | GATA3, YAP1, APEX1, CTNNB1, ATF2, BRCA1, ARNT, ZEB1, PSMD9, JUN, RB1, ARID1A, TGFB1I1, COPS5, PARK7, NR5A1, ESR2, NFKB2, KAT2B, SRA1 |
transcription coactivator binding | molecular_function | ESR1, TERT, FOXO1, PPARA |
transcription cofactor activity | molecular_function | MUC1, NRG1, KAT2B |
transcription cofactor binding | molecular_function | NFE2L2 |
transcription corepressor activity | molecular_function | YAP1, CCND1, NR2F2, APEX1, TOB1, ZEB1, ENO1, C1QBP, FOXP3, SIRT1, DNMT3B, NR0B2, ZNF366, WNT4, NANOG |
transcription factor activity, protein binding | molecular_function | SMAD3, HEY1, SMAD4 |
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular_function | EGR1, JUN, CLOCK, FOS |
transcription factor activity, RNA polymerase II core promoter sequence-specific | molecular_function | SMAD3, HEY1 |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | molecular_function | ATF2, USF1, HNF1B, ARNT, JUN, MEIS1, NR5A2, RELA, HIF1A, NR5A1, FOXP3, GATA6, USF2, GATA5 |
transcription factor activity, RNA polymerase II transcription factor binding | molecular_function | YAP1, ATF2, HIF1A, SMAD4 |
transcription factor activity, RNA polymerase II transcription factor recruiting | molecular_function | LIF |
transcription factor activity, sequence-specific DNA binding | molecular_function | EGR1, GATA3, BCL6, STAT3, NR2F2, CDX1, WNT5A, PPARG, HMGB1, CTNNB1, ATF2, NFKB1, HMGA1, AR, AHR, NOTCH1, ID1, VDR, GATA2, USF1, HOXB2, STAT6, WT1, HNF1B, ARNT, SOX2, ZEB1, ESR1, JUN, CLOCK, TP53, MYC, ENO1, SMAD7, NR5A2, RB1, SOX15, KLF11, FOS, NR3C1, PRDM1, PGR, RUNX3, YBX1, SMAD3, RELA, FOXL2, HIF1A, FOXP1, FOXO1, NR5A1, HSF1, SMAD2, HEY1, NFE2L2, ESR2, PPARA, NFKB2, POU5F1, HDAC1, FOXP3, STAT4, SMAD4, TWIST1, TP63, KLF10, GATA6, USF2, KLF9, TBPL2, NANOG, GATA5, TBX21, MAF, CREB3L1 |
transcription factor activity, transcription factor binding | molecular_function | HMGA2, ARNT, HIF1A, FOXO1, TP63 |
transcription factor binding | molecular_function | GSK3B, BCL2, GATA3, CCND1, STAT3, HMGA2, PPARG, MAPK1, HMGB1, PIK3R1, GPX3, CTNNB1, ATF2, NFKB1, HMGA1, AR, AHR, ID1, AGTR2, GATA2, ARNT, ZEB1, ESR1, JUN, TP53, MYC, RB1, FOS, PSMD10, C1QBP, HDAC2, SMAD3, RELA, PARK7, HIF1A, HES5, FOXO1, SMAD2, HEY1, POU5F1, KAT2B, HDAC1, SIRT1, TWIST1, NR0B2, CDKN2A, GATA6, PAX2, PPRC1 |
transcription regulatory region DNA binding | molecular_function | EGR1, GATA3, YAP1, STAT3, CDX1, WNT5A, PPARG, CTNNB1, BRCA1, NFKB1, AR, AHR, WT1, HNF1B, SOX2, JUN, TP53, TNF, SMAD7, NR5A2, KLF11, FOS, WNT1, SMAD3, RELA, NFE2L2, POU5F1, HDAC1, SMAD4, TP63, GATA6, PAX2, DLX5, GATA5, TBX21, CREB3L1 |
transcription regulatory region sequence-specific DNA binding | molecular_function | EGR1, GATA3, NFKB1, SOX2, SUV39H1, NR5A2, NR5A1, NFE2L2, POU5F1, HDAC1, SUV39H2 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular_function | EGR1, GATA3, STAT3, HMGA2, ATF2, AR, GATA2, HOXA10, WT1, SOX2, ESR1, JUN, MYC, MEIS1, NR5A2, FOS, NR3C1, PGR, YBX1, RELA, FOXL2, HIF1A, SMAD2, PPARA, NFKB2, SMAD4, TP63, DLX5, CREB3L1 |
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | molecular_function | CDX1, NFKB1, HMGA1, RELA, NFE2L2 |
transcriptional activator activity, RNA polymerase II transcription factor binding | molecular_function | NOTCH1, JUN, CLOCK, PPARA |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular_function | GATA3, STAT3, ATF2, GATA2, TP53, HIF1A, SMAD4, GATA6, GATA5, MAF |
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular_function | GATA3, HMGA2, SNAI1, PRDM1, RELA, HES5, FOXO1, HSF1, PPARA |
transcriptional repressor activity, RNA polymerase II transcription factor binding | molecular_function | AHRR |
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular_function | BCL6, NFKB1, ZEB1, SNAI1, FOXO1, POU5F1 |
transferase activity | molecular_function | GSK3B, FGFR1, SRC, MET, DNMT1, MAPK1, FGFR2, KIT, AKT1, ATF2, ERBB3, NME1, KDR, FLT4, BRAF, PDGFRA, AXL, JAK1, TYK2, FLT1, GSTP1, GSTM1, NAT2, TYMP, PIK3CA, COMT, FLT3, MTOR, GSTT1, MAT2A, CHEK2, GSTZ1, AURKA, INSR, EGFR, CLOCK, MAP3K7, IGF1R, PRKCB, SUV39H1, TERT, ERBB2, LATS1, FYN, SGK1, BMPR1B, MAP2K7, KALRN, PRDM1, PAK4, PNP, CSF1R, GALT, PLK1, PTK2, DNMT3A, NTRK2, TYRO3, TEK, PAK1, ACLY, XYLT2, KAT2B, MST1R, EZH2, ATM, LIMK1, EHMT2, DAPK1, DNMT3B, PIM2, AMHR2, SUV39H2, DAD1, GBGT1, CHST6, CHST2, SULT1E1, PEMT |
transferase activity, transferring acyl groups | molecular_function | LIPC, NAT2, CLOCK, KAT2B |
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | molecular_function | ACLY |
transferase activity, transferring glycosyl groups | molecular_function | TYMP, PNP, XYLT2, DAD1, GBGT1 |
transferase activity, transferring hexosyl groups | molecular_function | GBGT1 |
transferase activity, transferring pentosyl groups | molecular_function | TYMP, PNP |
transferrin receptor binding | molecular_function | TF |
transforming growth factor beta binding | molecular_function | CD36, ENG, ITGAV, THBS1 |
transforming growth factor beta receptor activity, type I | molecular_function | BMPR1B |
transforming growth factor beta receptor activity, type II | molecular_function | AMHR2 |
transforming growth factor beta receptor binding | molecular_function | INHBA, BMP4, BMP6, TGFB1, INHA, MSTN, GDF9, AMH, TGFB2, SMAD3, SMAD2, NODAL, GDF15 |
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity | molecular_function | SMAD4 |
transforming growth factor beta receptor, cytoplasmic mediator activity | molecular_function | CDKN1B, ENG |
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity | molecular_function | SMAD7 |
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | molecular_function | SMAD3, SMAD2 |
transforming growth factor beta-activated receptor activity | molecular_function | ENG |
translation initiation factor activity | molecular_function | COPS5, EIF3E |
translation initiation factor binding | molecular_function | EIF4EBP1 |
translation repressor activity | molecular_function | EIF4EBP1 |
transmembrane receptor protein serine/threonine kinase activity | molecular_function | BMPR1B, AMHR2 |
transmembrane receptor protein tyrosine kinase activator activity | molecular_function | GREM1, EGF, NRG1 |
transmembrane receptor protein tyrosine kinase activity | molecular_function | FGFR1, MET, FGFR2, KIT, KDR, FLT4, PDGFRA, AXL, FLT1, FLT3, INSR, EGFR, IGF1R, ERBB2, CSF1R, NTRK2, TYRO3, TEK, MST1R |
transmembrane receptor protein tyrosine kinase adaptor activity | molecular_function | PIK3R1, SHC1 |
transmembrane receptor protein tyrosine phosphatase activity | molecular_function | PTPRR |
transmembrane signaling receptor activity | molecular_function | CRHR1, ERBB3, ENG, IL1R1, CD79A, FAS, LEPR, KLRC1, SELE, MRC1, FCER1G, EGFR, LGR5, TLR2, TLR4, ERBB2, CD4, CLDN4, TLR3, CLDN3, ICAM1, TLR9, AGER, KLRD1, TRPV1, CD69, CRHR2, IL11RA |
transmembrane transporter activity | molecular_function | ATP5A1, GJA1, ATP5B, SLC22A23 |
transporter activity | molecular_function | PTGDS, IGF2R, RBP1, AQP2, ATP5B, SLC22A23, AQP8, ABCB1, SYP, SCARB1, ABCG2, AQP5, SLCO2A1, SLCO4A1 |
triacyl lipopeptide binding | molecular_function | TLR2 |
triglyceride binding | molecular_function | CETP |
triglyceride lipase activity | molecular_function | LIPC |
tripeptidyl-peptidase activity | molecular_function | ACE |
tRNA binding | molecular_function | TERT |
tropomyosin binding | molecular_function | S100A6, TMOD3, CALD1 |
tryptophan 2,3-dioxygenase activity | molecular_function | IDO1 |
tubulin binding | molecular_function | BRCA1, MAP2, STMN1, BIRC5, FYN |
tumor necrosis factor binding | molecular_function | TNFRSF1A, A2M |
tumor necrosis factor receptor binding | molecular_function | CD40LG, TNFSF10, FASLG, TNF, LTA, TNFSF13B |
tumor necrosis factor receptor superfamily binding | molecular_function | TNFSF10 |
tumor necrosis factor-activated receptor activity | molecular_function | TNFRSF1A, TNFRSF1B, CD40, FAS, TNFRSF11B, TNFRSF21 |
type 1 angiotensin receptor binding | molecular_function | TYK2 |
type 1 metabotropic glutamate receptor binding | molecular_function | ESR1 |
type I activin receptor binding | molecular_function | NODAL |
type I transforming growth factor beta receptor binding | molecular_function | ENG, TGFB1, SMAD7, SMAD2 |
type II activin receptor binding | molecular_function | INHBA |
type II transforming growth factor beta receptor binding | molecular_function | ENG, TGFB1, TGFB2 |
type III transforming growth factor beta receptor binding | molecular_function | TGFB1, TGFB2 |
tyrosine 3-monooxygenase activator activity | molecular_function | PARK7 |
U1 snRNA binding | molecular_function | ISG20 |
U2 snRNA binding | molecular_function | ISG20 |
U3 snoRNA binding | molecular_function | ISG20 |
ubiquitin binding | molecular_function | UCHL1, HSPB1, SMAD3, CXCR4 |
ubiquitin conjugating enzyme binding | molecular_function | FOXL2, PPARA |
ubiquitin protein ligase activity | molecular_function | CDC42 |
ubiquitin protein ligase binding | molecular_function | GSK3B, BCL2, HSPD1, PRDX6, CLU, BRCA1, UCHL1, CDKN1A, TNFRSF1B, CD40, JAK1, CHEK2, AURKA, EGFR, TP53, SMAD7, RB1, SMAD3, RELA, HIF1A, FOXO1, CXCR4, SMAD2, POU5F1, GABARAPL1, PTPN22, FHIT |
ubiquitin-like protein conjugating enzyme binding | molecular_function | PARK7 |
ubiquitin-protein transferase activity | molecular_function | BRCA1, BIRC5, TRIM36 |
ubiquitin-protein transferase inhibitor activity | molecular_function | CDKN2A |
ubiquitin-specific protease binding | molecular_function | PARK7 |
UDP-glucose:hexose-1-phosphate uridylyltransferase activity | molecular_function | GALT |
unfolded protein binding | molecular_function | HSPD1, HSPA6, HSP90AA1, CRYAB, APCS |
unmethylated CpG binding | molecular_function | DNMT1, DNMT3A, DNMT3B |
uracil DNA N-glycosylase activity | molecular_function | APEX1 |
urokinase plasminogen activator receptor activity | molecular_function | PLAUR |
UTP binding | molecular_function | HSP90AA1 |
vascular endothelial growth factor binding | molecular_function | KDR, PDGFRA, PTN, NRP1 |
vascular endothelial growth factor receptor 1 binding | molecular_function | VEGFA |
vascular endothelial growth factor receptor 2 binding | molecular_function | VEGFA, GREM1, ITGB3 |
vascular endothelial growth factor receptor 3 binding | molecular_function | VEGFC, FIGF |
vascular endothelial growth factor receptor binding | molecular_function | VEGFA, FIGF |
vascular endothelial growth factor-activated receptor activity | molecular_function | KDR, FLT4, PDGFRA, FLT1, FLT3, NRP1, NRP2 |
vasopressin receptor activity | molecular_function | OXTR |
VEGF-A-activated receptor activity | molecular_function | FLT1 |
VEGF-B-activated receptor activity | molecular_function | FLT1 |
very-low-density lipoprotein particle receptor binding | molecular_function | APOE |
vinculin binding | molecular_function | CTNNA1 |
virion binding | molecular_function | PTX3, CRP, APCS, NECTIN1 |
virus receptor activity | molecular_function | CCR5, AXL, ITGA2, ITGB5, NCAM1, ITGB6, MRC1, ITGB3, ITGB1, ITGAV, CD4, ICAM1, TYRO3, CXCR4, NECTIN1, SCARB1, NECTIN4 |
vitamin D 24-hydroxylase activity | molecular_function | CYP1A1 |
vitamin D binding | molecular_function | GC |
vitamin D response element binding | molecular_function | VDR |
vitamin E binding | molecular_function | AFM |
vitamin transporter activity | molecular_function | GC |
voltage-gated calcium channel activity | molecular_function | OPRM1, ITGAV, GAS6 |
voltage-gated chloride channel activity | molecular_function | CLCN3 |
voltage-gated ion channel activity | molecular_function | CLCN3 |
volume-sensitive chloride channel activity | molecular_function | CLCN3 |
water channel activity | molecular_function | AQP2, AQP8, AQP5 |
water transmembrane transporter activity | molecular_function | AQP2 |
Wnt-activated receptor activity | molecular_function | EGF, SFRP4 |
Wnt-protein binding | molecular_function | EGF, SFRP4 |
WW domain binding | molecular_function | TP63 |
xanthine dehydrogenase activity | molecular_function | XDH |
xanthine oxidase activity | molecular_function | XDH |
xenobiotic-transporting ATPase activity | molecular_function | ABCB1, ABCG2 |
Y-form DNA binding | molecular_function | MSH2 |
zinc ion binding | molecular_function | GATA3, NR2F2, DNMT1, MME, PPARG, MMP13, MMP9, BRCA1, AR, ACE, VDR, GATA2, MMP7, MMP10, MMP14, WT1, MMP11, ZEB1, MMP12, ESR1, CA2, SOD1, PRKCB, S100A6, TP53, SUV39H1, BIRC5, CD4, NR5A2, TGFB1I1, NR3C1, PGR, ADA, MMP1, GALT, MMP2, MMP3, SMAD3, S100A13, NR5A1, ESR2, PPARA, ADAM17, LIMK1, EHMT2, TRIM36, ADAM8, ADAM22, GATA6, SUV39H2, PAPPA, CHD5, CPB2, GATA5, MMP24, TET2, TET1, PIAS3 |