Gene id
173
Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed references
Gene Summary
Gene Symbol
AFM Gene UCSC Ensembl
Aliases
ALB2, ALBA, ALF
Gene name
afamin
Alternate names
afamin, alpha-Alb, alpha-albumin,
Gene location
4q13.3 (73481739: 73504000) Exons: 15 NC_000004.12
Gene summary(Entrez)
This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream. [provided by RefSeq, Jul 2008]
OMIM
104145
Protein Summary
Protein general information
P43652 Name: Afamin (Alpha albumin) (Alpha Alb)Length: 599 Mass: 69,069 Tissue specificity: High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level). {ECOSequence
MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKD RCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQA YESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCG ALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIK ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQ IYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSL GEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFS QDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN Structural information
Other Databases
GeneCards: AFM;   Malacards: AFM
Gene ontology
Expand/Collapse
GO accession Term name Evidence code Go category
GO:0005576
extracellular region
TAS
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0008431
vitamin E binding
IPI
molecular_function
GO:0008431
vitamin E binding
IDA
molecular_function
GO:0051180
vitamin transport
IDA
biological_process
GO:0051180
vitamin transport
IDA
biological_process
GO:0070062
extracellular exosome
IDA
cellular_component
GO:0070062
extracellular exosome
IDA
cellular_component
GO:0072562
blood microparticle
IDA
cellular_component
GO:0005576
extracellular region
IEA
cellular_component
GO:0005576
extracellular region
IEA
cellular_component
GO:0005576
extracellular region
TAS
cellular_component
GO:0005615
extracellular space
IEA
cellular_component
GO:0005615
extracellular space
IEA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0006810
transport
IEA
biological_process
GO:0006810
transport
IEA
biological_process
GO:0008431
vitamin E binding
IPI
molecular_function
GO:0008431
vitamin E binding
IDA
molecular_function
GO:0051180
vitamin transport
IDA
biological_process
GO:0051180
vitamin transport
IDA
biological_process
GO:0070062
extracellular exosome
IDA
cellular_component
GO:0070062
extracellular exosome
IDA
cellular_component
GO:0072562
blood microparticle
IDA
cellular_component
GO:0005576
extracellular region
TAS
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0005615
extracellular space
IDA
cellular_component
GO:0008431
vitamin E binding
IPI
molecular_function
GO:0008431
vitamin E binding
IDA
molecular_function
GO:0051180
vitamin transport
IDA
biological_process
GO:0051180
vitamin transport
IDA
biological_process
GO:0070062
extracellular exosome
IDA
cellular_component
GO:0070062
extracellular exosome
IDA
cellular_component
GO:0072562
blood microparticle
IDA
cellular_component
Diseases
Associated diseases
References
Endometriosis PMID: 20858448
Endometriosis INFBASE20858448
PubMed references
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PMID
Condition
Mutation
Ethnicity
Population details
Infertility_type
Associated_genes
Abstract
20858448
Endometrio sis
242 reproducti ve-age women wa s to determine the concentrati on of afamin in the serum and peritoneal flui d of women with and without en dometriosis
afamin
Show abstract