Endometriosis Knowledgebase


A repository for genes associated with endometriosis

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Gene id 406966
Gene Summary                KEGG pathways    Diseases    PubMed references    

Gene Summary

Gene Symbol MIR191   Gene   UCSC   Ensembl
Aliases MIRN191, miR-191
Gene name microRNA 191
Alternate names hsa-mir-191,
Gene location 3p21.31 (87497227: 87708633)     Exons: 30     NC_000009.12
Gene summary(Entrez) microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
OMIM 615150

Diseases

Associated diseases References
Endometriosis INFBASE26191186

PubMed references


PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
26191186 Endometrio
sis


MIR191
DAPK1
Show abstract