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A repository for genes associated with endometriosis

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Gene id 8850
Gene Summary        Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed references    

Gene Summary

Gene Symbol KAT2B   Gene   UCSC   Ensembl
Aliases CAF, P/CAF, PCAF
Gene name lysine acetyltransferase 2B
Alternate names histone acetyltransferase KAT2B, CREBBP-associated factor, K(lysine) acetyltransferase 2B, histone acetylase PCAF, histone acetyltransferase PCAF, p300/CBP-associated factor,
Gene location 3p24.3 (20040031: 20154403)     Exons: 19     NC_000003.12
Gene summary(Entrez) CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
OMIM 602303

Protein Summary

Protein general information Q92831  

Name: Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP associated factor) (P/CAF)

Length: 832  Mass: 93,013

Tissue specificity: Ubiquitously expressed but most abundant in heart and skeletal muscle. {ECO

Sequence MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARI
AVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHL
ENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGV
NNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR
YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSR
TSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIP
MELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQ
LPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH
DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIE
RKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFME
PVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIK
EAGLIDK
Structural information
Protein Domains
N-acetyltransferase. (503-651)
Bromo. (740-810)
Interpro:  IPR016181 IPR001487 IPR018359 IPR016376 IPR000182 IPR009464
Prosite:   PS00633 PS50014 PS51186

Pfam:  
PF00583 PF00439 PF06466

PDB:  
1CM0 1JM4 1N72 1WUG 1WUM 1ZS5 2RNW 2RNX 3GG3 4NSQ 5FDZ 5FE0 5FE1 5FE2 5FE3 5FE4 5FE5 5FE6 5FE7 5FE8 5FE9 5LVQ 5LVR
PDBsum:   1CM0 1JM4 1N72 1WUG 1WUM 1ZS5 2RNW 2RNX 3GG3 4NSQ 5FDZ 5FE0 5FE1 5FE2 5FE3 5FE4 5FE5 5FE6 5FE7 5FE8 5FE9 5LVQ 5LVR

DIP:  
29778
MINT:   150079
STRING:   ENSP00000263754;
Other Databases GeneCards:  KAT2B;  Malacards:  KAT2B

Gene ontology


GO accessionTerm nameEvidence codeGo category
GO:0000125 PCAF complex
NAS cellular_component
GO:0000776 kinetochore
IEA cellular_component
GO:0000790 nuclear chromatin
IEA cellular_component
GO:0000977 RNA polymerase II regulat
ory region sequence-speci
fic DNA binding
IEA molecular_function
GO:0003682 chromatin binding
ISS molecular_function
GO:0003712 transcription cofactor ac
tivity
IPI molecular_function
GO:0003713 transcription coactivator
activity
IDA molecular_function
GO:0003713 transcription coactivator
activity
IDA molecular_function
GO:0004402 histone acetyltransferase
activity
IDA molecular_function
GO:0004402 histone acetyltransferase
activity
IMP molecular_function
GO:0004402 histone acetyltransferase
activity
EXP molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
ISS molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004861 cyclin-dependent protein
serine/threonine kinase i
nhibitor activity
ISS molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005634 nucleus
ISS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005671 Ada2/Gcn5/Ada3 transcript
ion activator complex
IDA cellular_component
GO:0005829 cytosol
IEA cellular_component
GO:0006338 chromatin remodeling
NAS biological_process
GO:0006338 chromatin remodeling
IDA biological_process
GO:0006367 transcription initiation
from RNA polymerase II pr
omoter
TAS biological_process
GO:0006367 transcription initiation
from RNA polymerase II pr
omoter
TAS biological_process
GO:0006473 protein acetylation
TAS biological_process
GO:0007050 cell cycle arrest
TAS biological_process
GO:0007219 Notch signaling pathway
TAS biological_process
GO:0007613 memory
IEA biological_process
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008285 negative regulation of ce
ll proliferation
IDA biological_process
GO:0010835 regulation of protein ADP
-ribosylation
IDA biological_process
GO:0010976 positive regulation of ne
uron projection developme
nt
IEA biological_process
GO:0016032 viral process
IEA biological_process
GO:0016407 acetyltransferase activit
y
IDA molecular_function
GO:0016407 acetyltransferase activit
y
IDA molecular_function
GO:0018076 N-terminal peptidyl-lysin
e acetylation
IDA biological_process
GO:0018393 internal peptidyl-lysine
acetylation
IDA biological_process
GO:0018394 peptidyl-lysine acetylati
on
IDA biological_process
GO:0018394 peptidyl-lysine acetylati
on
IDA biological_process
GO:0019901 protein kinase binding
ISS molecular_function
GO:0031672 A band
IEA cellular_component
GO:0031674 I band
IEA cellular_component
GO:0032403 protein complex binding
IDA molecular_function
GO:0032869 cellular response to insu
lin stimulus
IDA biological_process
GO:0034599 cellular response to oxid
ative stress
IEA biological_process
GO:0035035 histone acetyltransferase
binding
IEA molecular_function
GO:0035563 positive regulation of ch
romatin binding
IEA biological_process
GO:0035948 positive regulation of gl
uconeogenesis by positive
regulation of transcript
ion from RNA polymerase I
I promoter
IEA biological_process
GO:0042641 actomyosin
IEA cellular_component
GO:0042826 histone deacetylase bindi
ng
IPI molecular_function
GO:0043966 histone H3 acetylation
IDA biological_process
GO:0043970 histone H3-K9 acetylation
IEA biological_process
GO:0045736 negative regulation of cy
clin-dependent protein se
rine/threonine kinase act
ivity
IEA biological_process
GO:0045815 positive regulation of ge
ne expression, epigenetic
TAS biological_process
GO:0045909 positive regulation of va
sodilation
IEA biological_process
GO:0045944 positive regulation of tr
anscription from RNA poly
merase II promoter
IDA biological_process
GO:0048511 rhythmic process
IEA biological_process
GO:0071374 cellular response to para
thyroid hormone stimulus
IEA biological_process
GO:0071442 positive regulation of hi
stone H3-K14 acetylation
IEA biological_process
GO:2000617 positive regulation of hi
stone H3-K9 acetylation
IEA biological_process
GO:0000123 histone acetyltransferase
complex
IEA cellular_component
GO:0000125 PCAF complex
NAS cellular_component
GO:0000776 kinetochore
IEA cellular_component
GO:0000790 nuclear chromatin
IEA cellular_component
GO:0000977 RNA polymerase II regulat
ory region sequence-speci
fic DNA binding
IEA molecular_function
GO:0003682 chromatin binding
IEA molecular_function
GO:0003682 chromatin binding
ISS molecular_function
GO:0003712 transcription cofactor ac
tivity
IPI molecular_function
GO:0003713 transcription coactivator
activity
IEA molecular_function
GO:0003713 transcription coactivator
activity
IDA molecular_function
GO:0003713 transcription coactivator
activity
IDA molecular_function
GO:0004402 histone acetyltransferase
activity
IEA molecular_function
GO:0004402 histone acetyltransferase
activity
IEA molecular_function
GO:0004402 histone acetyltransferase
activity
IEA molecular_function
GO:0004402 histone acetyltransferase
activity
IDA molecular_function
GO:0004402 histone acetyltransferase
activity
IMP molecular_function
GO:0004402 histone acetyltransferase
activity
EXP molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IEA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
ISS molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004861 cyclin-dependent protein
serine/threonine kinase i
nhibitor activity
IEA molecular_function
GO:0004861 cyclin-dependent protein
serine/threonine kinase i
nhibitor activity
ISS molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005634 nucleus
IEA cellular_component
GO:0005634 nucleus
IEA cellular_component
GO:0005634 nucleus
ISS cellular_component
GO:0005634 nucleus
IEA cellular_component
GO:0005634 nucleus
IEA cellular_component
GO:0005634 nucleus
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005671 Ada2/Gcn5/Ada3 transcript
ion activator complex
IEA cellular_component
GO:0005671 Ada2/Gcn5/Ada3 transcript
ion activator complex
IDA cellular_component
GO:0005829 cytosol
IEA cellular_component
GO:0006338 chromatin remodeling
NAS biological_process
GO:0006338 chromatin remodeling
IDA biological_process
GO:0006338 chromatin remodeling
TAS biological_process
GO:0006351 transcription, DNA-templa
ted
IEA biological_process
GO:0006355 regulation of transcripti
on, DNA-templated
IEA biological_process
GO:0006355 regulation of transcripti
on, DNA-templated
IEA biological_process
GO:0006367 transcription initiation
from RNA polymerase II pr
omoter
TAS biological_process
GO:0006367 transcription initiation
from RNA polymerase II pr
omoter
TAS biological_process
GO:0006473 protein acetylation
IEA biological_process
GO:0006473 protein acetylation
TAS biological_process
GO:0007049 cell cycle
IEA biological_process
GO:0007050 cell cycle arrest
TAS biological_process
GO:0007219 Notch signaling pathway
TAS biological_process
GO:0007613 memory
IEA biological_process
GO:0008080 N-acetyltransferase activ
ity
IEA molecular_function
GO:0008134 transcription factor bind
ing
IEA molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008285 negative regulation of ce
ll proliferation
IDA biological_process
GO:0010835 regulation of protein ADP
-ribosylation
IDA biological_process
GO:0010976 positive regulation of ne
uron projection developme
nt
IEA biological_process
GO:0016032 viral process
IEA biological_process
GO:0016407 acetyltransferase activit
y
IDA molecular_function
GO:0016407 acetyltransferase activit
y
IDA molecular_function
GO:0016573 histone acetylation
IEA biological_process
GO:0016573 histone acetylation
IEA biological_process
GO:0016740 transferase activity
IEA molecular_function
GO:0016746 transferase activity, tra
nsferring acyl groups
IEA molecular_function
GO:0018076 N-terminal peptidyl-lysin
e acetylation
IDA biological_process
GO:0018393 internal peptidyl-lysine
acetylation
IEA biological_process
GO:0018393 internal peptidyl-lysine
acetylation
IDA biological_process
GO:0018394 peptidyl-lysine acetylati
on
IDA biological_process
GO:0018394 peptidyl-lysine acetylati
on
IDA biological_process
GO:0019901 protein kinase binding
IEA molecular_function
GO:0019901 protein kinase binding
ISS molecular_function
GO:0031672 A band
IEA cellular_component
GO:0031674 I band
IEA cellular_component
GO:0032403 protein complex binding
IDA molecular_function
GO:0032869 cellular response to insu
lin stimulus
IDA biological_process
GO:0034599 cellular response to oxid
ative stress
IEA biological_process
GO:0035035 histone acetyltransferase
binding
IEA molecular_function
GO:0035563 positive regulation of ch
romatin binding
IEA biological_process
GO:0035948 positive regulation of gl
uconeogenesis by positive
regulation of transcript
ion from RNA polymerase I
I promoter
IEA biological_process
GO:0042641 actomyosin
IEA cellular_component
GO:0042826 histone deacetylase bindi
ng
IEA molecular_function
GO:0042826 histone deacetylase bindi
ng
IPI molecular_function
GO:0043966 histone H3 acetylation
IDA biological_process
GO:0043970 histone H3-K9 acetylation
IEA biological_process
GO:0045736 negative regulation of cy
clin-dependent protein se
rine/threonine kinase act
ivity
IEA biological_process
GO:0045815 positive regulation of ge
ne expression, epigenetic
TAS biological_process
GO:0045893 positive regulation of tr
anscription, DNA-template
d
IEA biological_process
GO:0045909 positive regulation of va
sodilation
IEA biological_process
GO:0045944 positive regulation of tr
anscription from RNA poly
merase II promoter
IEA biological_process
GO:0045944 positive regulation of tr
anscription from RNA poly
merase II promoter
IDA biological_process
GO:0048511 rhythmic process
IEA biological_process
GO:0071374 cellular response to para
thyroid hormone stimulus
IEA biological_process
GO:0071442 positive regulation of hi
stone H3-K14 acetylation
IEA biological_process
GO:2000617 positive regulation of hi
stone H3-K9 acetylation
IEA biological_process
GO:0000125 PCAF complex
NAS cellular_component
GO:0003682 chromatin binding
ISS molecular_function
GO:0003712 transcription cofactor ac
tivity
IPI molecular_function
GO:0003713 transcription coactivator
activity
IDA molecular_function
GO:0003713 transcription coactivator
activity
IDA molecular_function
GO:0004402 histone acetyltransferase
activity
IDA molecular_function
GO:0004402 histone acetyltransferase
activity
IMP molecular_function
GO:0004402 histone acetyltransferase
activity
EXP molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
ISS molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004468 lysine N-acetyltransferas
e activity, acting on ace
tyl phosphate as donor
IDA molecular_function
GO:0004861 cyclin-dependent protein
serine/threonine kinase i
nhibitor activity
ISS molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005515 protein binding
IPI molecular_function
GO:0005634 nucleus
ISS cellular_component
GO:0005634 nucleus
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005654 nucleoplasm
TAS cellular_component
GO:0005671 Ada2/Gcn5/Ada3 transcript
ion activator complex
IDA cellular_component
GO:0006338 chromatin remodeling
NAS biological_process
GO:0006338 chromatin remodeling
IDA biological_process
GO:0006338 chromatin remodeling
TAS biological_process
GO:0006367 transcription initiation
from RNA polymerase II pr
omoter
TAS biological_process
GO:0006367 transcription initiation
from RNA polymerase II pr
omoter
TAS biological_process
GO:0006473 protein acetylation
TAS biological_process
GO:0007050 cell cycle arrest
TAS biological_process
GO:0007219 Notch signaling pathway
TAS biological_process
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008134 transcription factor bind
ing
IPI molecular_function
GO:0008285 negative regulation of ce
ll proliferation
IDA biological_process
GO:0010835 regulation of protein ADP
-ribosylation
IDA biological_process
GO:0016407 acetyltransferase activit
y
IDA molecular_function
GO:0016407 acetyltransferase activit
y
IDA molecular_function
GO:0018076 N-terminal peptidyl-lysin
e acetylation
IDA biological_process
GO:0018393 internal peptidyl-lysine
acetylation
IDA biological_process
GO:0018394 peptidyl-lysine acetylati
on
IDA biological_process
GO:0018394 peptidyl-lysine acetylati
on
IDA biological_process
GO:0019901 protein kinase binding
ISS molecular_function
GO:0032403 protein complex binding
IDA molecular_function
GO:0032869 cellular response to insu
lin stimulus
IDA biological_process
GO:0042826 histone deacetylase bindi
ng
IPI molecular_function
GO:0043966 histone H3 acetylation
IDA biological_process
GO:0045815 positive regulation of ge
ne expression, epigenetic
TAS biological_process
GO:0045944 positive regulation of tr
anscription from RNA poly
merase II promoter
IDA biological_process

KEGG pathways

hsa05166  HTLV-I infection
hsa05203  Viral carcinogenesis
hsa04919  Thyroid hormone signaling pathway
hsa04330  Notch signaling pathway

Diseases

Associated diseases References
Cancer PMID: 19950226
Endometriosis PMID: 23080547
Endometriosis INFBASE23080547

PubMed references


PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
23080547 Endometrio
sis

15 patients wit
h endometriosis
SIRT1
HDAC1
SUV39H1
SUV39H2
HDAC2
G9a
Show abstract