Results
| PMID | 11605057 |
| Gene Name | PTGS2 |
| Condition | Endometriosis |
| Association |
Associated |
| Sex | Female |
| Associated genes | VEGF, COX-2 |
| Other associated phenotypes |
Endometriosis |
|
Oncol Rep. 2001 Nov-Dec;8(6):1317-9. Deguchi, M| Ishiko, O| Sumi, T| Yoshida, H| Yamamoto, K| Ogita, S Department of Obstetrics and Gynecology, Osaka City General Hospital, Osaka 534-0021, Japan. The expression of vascular endothelial growth factor (VEGF) and cyclooxygenase-2 (COX-2) were immunohistochemically examined in both pelvic and extrapelvic endometriotic lesions. Different expressions of VEGF and COX-2 were observed in both lesions. VEGF immunoreactivity was distributed mainly in the cytoplasm of the adenocytes in inguinal tumors, but was not seen in ovarian tumors. COX-2 showed the same findings. These results suggest that angiogenesis may be involved in the pathogenesis of extrapelvic endometriosis. Mesh Terms: Abdominal Neoplasms/diagnosis/*metabolism/*pathology| Adult| Cyclooxygenase 2| Endometriosis/diagnosis/*metabolism/*pathology| Endothelial Growth Factors/*metabolism| Female| Humans| Immunohistochemistry| Inguinal Canal| Isoenzymes/*metabolism| |
|