Endometriosis Knowledgebase


A repository for genes associated with endometriosis

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PMID 17261287
Gene Name CCR1
Condition Endometriosis
Association Associated
Sex Female
Associated genes CCR1
Other associated phenotypes Endometriosis
Cognate chemokine receptor 1 messenger ribonucleic acid expression in peripheral blood as a diagnostic test for endometriosis.

Fertil Steril. 2007 Apr;87(4):982-4. Epub 2007 Jan 29.

Agic, Admir| Xu, Hong| Rehbein, Mirka| Wolfler, Monika M| Ebert, Andreas D| Hornung, Daniela



We investigated the expression of the cognate chemokine receptor 1 (CCR1) messenger ribonucleic acid, a G-protein-coupled cognate chemokine receptor with high affinity for RANTES (Regulated upon Activation, Normal T cells Expressed and Secreted), in peripheral blood leukocytes of women with and without endometriosis, and its potential use as a diagnostic test for endometriosis. Because patients with an earlier diagnosis of this disease have a better treatment outcome and a reduced recurrence rate, CCR1 mRNA measurement in the peripheral blood of patients with suspected endometriosis might give us a new perspective in diagnosing and treating this disease earlier and better.

Mesh Terms: CA-125 Antigen/blood| Endometriosis/blood/*diagnosis| Female| Humans| Leukocytes/*metabolism| Pregnancy| RNA, Messenger/*blood| Receptors, CCR1| Receptors, Chemokine/*genetics| Sensitivity and Specificity|DA 2007/05/02 09:00