Endometriosis Knowledgebase

PMID	18722603
Gene Name	WT1
Condition	Endometriosis
Association	Associated
Sex	Female
Associated genes	WT1
Other associated phenotypes	Deep endometriosis
Wilms' tumor gene 1 (WT1) overexpression in neurons in deep endometriosis: a pilot study. Fertil Steril. 2009 Apr;91(4 Suppl):1441-4. doi: Coosemans, An\| Moerman, Philippe\| Vergote, Ignace\| Koninckx, Philippe R\| Van Gool, Stefaan W\| Amant, Frederic Department of Obstetrics and Gynaecology, Experimental Laboratory of Gynaecology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium. Innervation of deep endometriosis has recently been linked to its severe pain symptoms. We demonstrated for the first time that the Wilms' tumor gene 1 is overexpressed in part of these nerves. Mesh Terms: Endometriosis/metabolism/pathology\| Female\| Gene Expression Regulation/physiology\| Genes, Wilms Tumor/physiology\| Humans\| Nerve Growth Factor/metabolism\| Neurons/metabolism/pathology\| Pilot Projects\| Receptor, trkA/metabolism\| S100 Proteins/m