Endometriosis Knowledgebase


A repository for genes associated with endometriosis

Results


PMID 19230253
Gene Name SAA1
Condition Endometriosis
Association Associated
Population size 50
Population details 50 (15 women without endometriosis, as confirmed by laparoscopy (group A), 35 patients with pelvic endometriosis)
Sex Female
Associated genes Ca 125 II, C-reactive protein (CRP), serum amyloid A (SAA), anticardiolipin antibody (aCL)
Other associated phenotypes Endometriosis
[The use of biochemical markers in diagnosis of endometriosis].

Akush Ginekol (Sofiia). 2008;47(4):19-22.

Nalbanski, A| Kiurkchiev, D



The aim of this study was to evaluate Ca 125 II, C-reactive protein (CRP) and serum amyloid A (SAA) and anticardiolipin antibody (aCL) concentrations for the diagnosis of pelvic endometriosis. The study population consisted of 15 women without endometriosis, as confirmed by laparoscopy (group A), and 35 patients with pelvic endometriosis. All of them were diagnosed by laparoscopy or laparotomy. Group B patients were divided into those at stages I and II of the disease (B I/II) and those at stages III and IV (B III/IV). Blood samples were obtained twice during the menstrual cycle: on day 1-3 of the cycle and on day 8-10 of the cycle. Our results claim that the measurement of these molecules may therefore provide a valuable tool in the diagnosis and management of endometriosis.

Mesh Terms: Adult| Antibodies, Anticardiolipin/blood| Biomarkers/blood| C-Reactive Protein/analysis| CA-125 Antigen/*blood| Case-Control Studies| Endometriosis/blood/*diagnosis| Female| Humans| Sensitivity and Specificity| Serum Amyloid A Protein/*analysis|