Endometriosis Knowledgebase


A repository for genes associated with endometriosis

Results


PMID 19931079
Gene Name GDF9
Condition Endometriosis
Association Associated
Sex Female
Infertility type Female infertility
Associated genes GDF-9
Other associated phenotypes Endometriosis
Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis.

Fertil Steril. 2010 Jul;94(2):758-60. doi: 10.1016/j.fertnstert.2009.10.011. Epub

Hendarto, Hendy| Prabowo, Prajitno| Moeloek, Farid Anfasa| Soetjipto, Soetjipto

Department of Obstetrics and Gynecology, Dr. Soetomo Hospital, Faculty of Medicine, University of Airlangga, Surabaya, Indonesia. hndhendy@yahoo.com

This study evaluated the level of growth differentiation factor 9 (GDF-9) in the follicular fluid of infertile women with endometriosis. The presence of GDF-9 in follicular fluid of preovulatory follicle was confirmed by Western blotting method in the band of 53 kDa, and GDF-9 concentration in women with severe endometriosis was lower than in those without.

Mesh Terms: Adult| Endometriosis/*metabolism| Female| Follicular Fluid/*metabolism| Follicular Phase/metabolism| Growth Differentiation Factor 9/*metabolism| Humans| Infertility, Female/*metabolism| Ovarian Follicle/metabolism| Severity of Illness Index| Yo