Endometriosis Knowledgebase

PMID	20378112
Gene Name	MMP9
Condition	Endometriosis
Association	Associated
Sex	Female
Associated genes	MMP-9, MMP-2, MMP-9/neutrophil gelatinase-associated lipocalin
Other associated phenotypes	Endometriosis
Matrix metalloproteinases are elevated in the urine of patients with endometriosis. Fertil Steril. 2010 Nov;94(6):2343-6. doi: 10.1016/j.fertnstert.2010.02.040. Epub Becker, Christian M\| Louis, Gwendolyn\| Exarhopoulos, Alexis\| Mechsner, Sylvia\| Ebert, Andreas D\| Zurakowski, David\| Moses, Marsha A Frauenklinik und Geburtshilfe, Charite, Universitatsklinikum Benjamin Franklin, Berlin, Germany. christian.becker@obs-gyn.ox.ac.uk In a prospective, blinded, longitudinal study MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin were significantly more likely to be detected in the urine of patients with endometriosis than in controls. Mesh Terms: Adult\| Biomarkers/metabolism/urine\| Case-Control Studies\| Endometriosis/enzymology/metabolism/urine\| Female\| Humans\| Matrix Metalloproteinase 2/urine\| Matrix Metalloproteinase 9/urine\| Matrix Metalloproteinases/metabolism/urine\| Up-Regulation\|