Results
| PMID | 20655530 |
| Gene Name | RLN1 |
| Condition | Endometriosis |
| Association |
Associated |
| Sex | Female |
| Associated genes | relaxin |
| Other associated phenotypes |
Endometriosis |
|
Fertil Steril. 2010 Dec;94(7):2885-7. doi: 10.1016/j.fertnstert.2010.06.051. Epub Morelli, Sara S| Petraglia, Felice| Weiss, Gerson| Luisi, Stefano| Florio, Pasquale| Wojtczuk, Andrea| Goldsmith, Laura T Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA. morellsa@umdnj.edu Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls. These data suggest that in normal and eutopic endometrium, relaxin may exert a protective effect against endometriosis. Mesh Terms: Adult| Case-Control Studies| Endometriosis/*genetics/metabolism/pathology| Endometrium/*metabolism/pathology| Female| Gene Expression/physiology| Humans| Menstrual Cycle/genetics/metabolism/physiology| Ovarian Diseases/*genetics/metabolism/patholo |
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