Results
| PMID | 20817169 |
| Gene Name | FSHR |
| Condition | Endometriosis |
| Association |
Associated |
| Mutation | A/G polymorphism of FSH receptor gene (Asn680Ser) |
| Population size | 637 |
| Population details | 637 (300 patients with endometriosis, 337 controls without endometriosis) |
| Sex | Female |
| Associated genes | FSHR |
| Other associated phenotypes |
Endometriosis |
|
Fertil Steril. 2011 Jan;95(1):455-7. doi: 10.1016/j.fertnstert.2010.07.1092. Wang, Hsin-Shih| Cheng, Bi-Hwa| Wu, Hsien-Ming| Yen, Chih-Feng| Liu, Chun-Ting| Chao, Angel| Wang, Tzu-Hao Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Lin-Kou Medical Center, Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. Six hundred thirty-seven Taiwanese Chinese women including 300 patients with endometriosis and 337 controls without endometriosis were enrolled to investigate the association between nonsynonymous single nucleotide polymorphism of the FSH receptor gene and the risk of endometriosis. For the A/G polymorphism of FSH receptor gene (Asn680Ser), a univariate analysis for women with endometriosis demonstrated that both the GG genotype (680Ser/Ser) and GA genotype (680Ser/Asn) were associated with a significantly lower risk of endometriosis. Mesh Terms: Adult| Asian Continental Ancestry Group/genetics/statistics & numerical data| Endometriosis/*epidemiology/*genetics| Female| Genetic Predisposition to Disease/epidemiology| Genotype| Humans| Middle Aged| *Polymorphism, Single Nucleotide| Receptor |
|