Results
| PMID | 21122834 |
| Gene Name | SERPINF1 |
| Condition | Endometriosis |
| Association |
Associated |
| Population size | 72 |
| Population details | 72 (42 patients with endometriosis, 30 patients without endometriosis) |
| Sex | Female |
| Associated genes | PEDF |
| Other associated phenotypes |
Endometriosis |
|
Fertil Steril. 2011 Apr;95(5):1798-800. doi: 10.1016/j.fertnstert.2010.10.042. Chen, Liqing| Fan, Ruijia| Huang, Xiufeng| Xu, Hong| Zhang, Xinmei Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China. To determine whether patients with endometriosis have altered levels of pigment epithelium-derived factor (PEDF) in peritoneal fluid, concentrations of PEDF in peritoneal fluid collected from 42 patients with endometriosis and 30 patients without endometriosis were measured with enzyme-linked immunosorbent assay. We detected significantly lower levels of peritoneal fluid PEDF in patients with endometriosis compared with patients without endometriosis, suggesting that peritoneal fluid PEDF plays a role in the pathogenesis of this disorder. Mesh Terms: Adult| Ascitic Fluid/*chemistry/metabolism/pathology| Case-Control Studies| Endometriosis/*metabolism/pathology| Eye Proteins/*analysis/metabolism| Female| Humans| Nerve Growth Factors/*analysis/metabolism| Osmolar Concentration| Peritoneal Disea |
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