Results
PMID | 21640343 |
Gene Name | IHH |
Condition | Endometriosis |
Association |
Associated |
Population size | 56 |
Population details | 56 (26 healthy volunteers, 30 women with endometriosis) |
Sex | Female |
Infertility type | Female infertility |
Associated genes | Hedgehog protein |
Other associated phenotypes |
Endometriosis |
Fertil Steril. 2011 Jun 30;95(8):2738-41.e1-3. doi: Smith, Kathryn| Alnifaidy, Redab| Wei, Qingxiang| Nieman, Lynnette K Program on Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1109, USA. Nuclear and cytoplasmic endometrial expression of Indian hedgehog increased from the late proliferative to mid and late secretory phases in 26 healthy volunteers compared with 30 women with endometriosis. The abnormal expression of Indian hedgehog protein in women with endometriosis suggests a resistance to P action. Mesh Terms: Adult| Biopsy| Case-Control Studies| Cell Nucleus/metabolism| Cytoplasm/metabolism| Down-Regulation| Endometriosis/*metabolism| Endometrium/*metabolism| Female| Hedgehog Proteins/*metabolism| Humans| Immunohistochemistry| Laparoscopy| Marylan |