Results
| PMID | 8073433 |
| Gene Name | CSF1 |
| Condition | Endometriosis |
| Association |
Associated |
| Population size | 44 |
| Population details | 44 infertile patients |
| Sex | Female |
| Infertility type | Female infertility |
| Associated genes | M-CSF |
| Other associated phenotypes |
Endometriosis associated infertility |
|
Tohoku J Exp Med. 1994 Mar;172(3):221-6. Fukaya, T| Sugawara, J| Yoshida, H| Yajima, A Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan. Macrophage colony stimulating factor (M-CSF) concentrations in the peritoneal fluid of 44 infertile patients were measured. The concentration of M-CSF was significantly higher in the patients with endometriosis than in those without endometriosis. There was no significant difference between the M-CSF concentration and stage of endometriosis classified by revised American Fertility Society (rAFS) classification in the 44 patients. However, in primary infertility patients with endometriosis there was a significant correlation between peritoneal M-CSF levels and rAFS points of endometriosis. We speculate that there is some relationship between the increased levels of M-CSF in the peritoneal cavity and the primary infertility associated with endometriosis especially progression of endometriosis. Mesh Terms: Ascitic Fluid/*metabolism| Endometriosis/complications/*metabolism| Enzyme-Linked Immunosorbent Assay| Female| Humans| Infertility, Female/complications/*metabolism| Macrophage Colony-Stimulating Factor/*metabolism|DA 1994/03/01 00:01 |
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